-
1
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
5
-
ER Fearon B Vogelstein 1990 A genetic model for colorectal tumorigenesis Cell 61 5 759 767
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
2
-
-
33745809820
-
Adenomatous polyposis coli (APC) differently regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells
-
26
-
J Yang W Zhang PM Evans 2006 Adenomatous polyposis coli (APC) differently regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells J Biol Chem 281 26 17751 17757
-
(2006)
J Biol Chem
, vol.281
, pp. 17751-17757
-
-
Yang, J.1
Zhang, W.2
Evans, P.M.3
-
3
-
-
34548174902
-
Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia
-
2
-
T Senda A Iizuka-Kogo T Onouchi 2007 Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia Med Mol Morphol 40 2 68 81
-
(2007)
Med Mol Morphol
, vol.40
, pp. 68-81
-
-
Senda, T.1
Iizuka-Kogo, A.2
Onouchi, T.3
-
5
-
-
0027535028
-
Identification of an alternative 5′ untranslated region of the adenomatous polyposis coli gene
-
6
-
S Lambertz WG Ballhausen 1993 Identification of an alternative 5′ untranslated region of the adenomatous polyposis coli gene Hum Genet 90 6 650 652
-
(1993)
Hum Genet
, vol.90
, pp. 650-652
-
-
Lambertz, S.1
Ballhausen, W.G.2
-
6
-
-
0028229809
-
Demonstration of promoter activity and alternative splicing in the region 5′ to exon 1 of the APC gene
-
11
-
A Thliveris W Samowitz N Matsunami 1994 Demonstration of promoter activity and alternative splicing in the region 5′ to exon 1 of the APC gene Cancer Res 54 11 2991 2995
-
(1994)
Cancer Res
, vol.54
, pp. 2991-2995
-
-
Thliveris, A.1
Samowitz, W.2
Matsunami, N.3
-
7
-
-
0034662626
-
Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer
-
16
-
M Esteller A Sparks M Toyota 2000 Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer Cancer Res 60 16 4366 4371
-
(2000)
Cancer Res
, vol.60
, pp. 4366-4371
-
-
Esteller, M.1
Sparks, A.2
Toyota, M.3
-
8
-
-
0034927849
-
Mismatch repair deficiency and CpG island hypermethylation in sporadic colon adenocarcinomas
-
7
-
Z Xiong AH Wu CM Bender 2001 Mismatch repair deficiency and CpG island hypermethylation in sporadic colon adenocarcinomas Cancer Epidemiol Biomarkers Prev 10 7 799 803
-
(2001)
Cancer Epidemiol Biomarkers Prev
, vol.10
, pp. 799-803
-
-
Xiong, Z.1
Wu, A.H.2
Bender, C.M.3
-
9
-
-
0034807280
-
Methylation and colorectal cancer
-
1
-
AM Jubb SM Bell P Quirke 2001 Methylation and colorectal cancer J Pathol 195 1 111 134
-
(2001)
J Pathol
, vol.195
, pp. 111-134
-
-
Jubb, A.M.1
Bell, S.M.2
Quirke, P.3
-
10
-
-
0027146559
-
Mutations of the APC (adenomatous polyposis coli) gene
-
6
-
H Nagase Y Nakamura 1993 Mutations of the APC (adenomatous polyposis coli) gene Hum Mutat 2 6 425 434
-
(1993)
Hum Mutat
, vol.2
, pp. 425-434
-
-
Nagase, H.1
Nakamura, Y.2
-
11
-
-
0027535407
-
Identification of APC gene mutations in Italian adenomatous polyposis coli patients by PCR-SSCP analysis
-
2
-
L Varesco V Gismondi R James 1993 Identification of APC gene mutations in Italian adenomatous polyposis coli patients by PCR-SSCP analysis Am J Hum Genet 52 2 280 285
-
(1993)
Am J Hum Genet
, vol.52
, pp. 280-285
-
-
Varesco, L.1
Gismondi, V.2
James, R.3
-
12
-
-
0032947835
-
Molecular analysis of the APC gene in 205 families: Extended genotype-phenotype correlations in FAP and evidence for the role of APC amino acid changes in colorectal cancer predisposition
-
1
-
YL Wallis DG Morton CM McKeown 1999 Molecular analysis of the APC gene in 205 families: extended genotype-phenotype correlations in FAP and evidence for the role of APC amino acid changes in colorectal cancer predisposition J Med Genet 36 1 14 20
-
(1999)
J Med Genet
, vol.36
, pp. 14-20
-
-
Wallis, Y.L.1
Morton, D.G.2
McKeown, C.M.3
-
13
-
-
33845373278
-
Colorectal cancer and genetic alterations in the Wnt pathway
-
57
-
S Segditsas I Tomlinson 2006 Colorectal cancer and genetic alterations in the Wnt pathway Oncogene 25 57 7531 7537
-
(2006)
Oncogene
, vol.25
, pp. 7531-7537
-
-
Segditsas, S.1
Tomlinson, I.2
-
14
-
-
0004136246
-
-
Cold Spring Harbor Laboratory New York, USA
-
Maniatis T, Fritsch EF, Sambrook J (1982) Molecular cloning, a laboratory manual. Cold Spring Harbor Laboratory, New York, USA
-
(1982)
Molecular Cloning, a Laboratory Manual
-
-
Maniatis, T.1
Fritsch, E.F.2
Sambrook, J.3
-
15
-
-
0026546877
-
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
-
5
-
M Frommer LE McDonald DS Millar 1992 A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands Proc Natl Acad Sci USA 89 5 1827 1831
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 1827-1831
-
-
Frommer, M.1
McDonald, L.E.2
Millar, D.S.3
-
16
-
-
0035870280
-
Epigenetic patterns in the progression of esophageal adenocarcinoma
-
8
-
CA Eads RV Lord K Wickramasinghe 2001 Epigenetic patterns in the progression of esophageal adenocarcinoma Cancer Res 61 8 3410 3418
-
(2001)
Cancer Res
, vol.61
, pp. 3410-3418
-
-
Eads, C.A.1
Lord, R.V.2
Wickramasinghe, K.3
-
18
-
-
0028231090
-
The 1993-94 Genethon human genetic linkage map
-
2 Spec No
-
G Gyapay J Morissette A Vignal 1994 The 1993-94 Genethon human genetic linkage map Nat Genet 7 2 Spec No 246 339
-
(1994)
Nat Genet
, vol.7
, pp. 246-339
-
-
Gyapay, G.1
Morissette, J.2
Vignal, A.3
-
19
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
3
-
J Groden A Thliveris W Samowitz 1991 Identification and characterization of the familial adenomatous polyposis coli gene Cell 66 3 589 600
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
-
20
-
-
11944252481
-
Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients
-
10
-
Y Miyoshi H Ando H Nagase 1992 Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients Proc Natl Acad Sci USA 89 10 4452 4456
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 4452-4456
-
-
Miyoshi, Y.1
Ando, H.2
Nagase, H.3
-
21
-
-
0043122919
-
SIFT: Predicting amino acid changes that affect protein function
-
13
-
PC Ng S Henikoff 2003 SIFT: predicting amino acid changes that affect protein function Nucleic Acids Res 31 13 3812 3814
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3812-3814
-
-
Ng, P.C.1
Henikoff, S.2
-
23
-
-
10344242920
-
Sequence-based prediction of pathological mutations
-
4
-
C Ferrer-Costa M Orozco X de la Cruz 2004 Sequence-based prediction of pathological mutations Proteins 57 4 811 819
-
(2004)
Proteins
, vol.57
, pp. 811-819
-
-
Ferrer-Costa, C.1
Orozco, M.2
De La Cruz, X.3
-
24
-
-
21244500864
-
APC promoter hypermethylation contributes to the loss of APC expression in colorectal cancers with allelic loss on 5q
-
10
-
CN Arnold A Goel D Niedzwiecki 2004 APC promoter hypermethylation contributes to the loss of APC expression in colorectal cancers with allelic loss on 5q Cancer Biol Ther 3 10 960 964
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 960-964
-
-
Arnold, C.N.1
Goel, A.2
Niedzwiecki, D.3
-
25
-
-
14644442314
-
Genetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instability
-
2
-
L Thorstensen GE Lind T Løvig 2005 Genetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instability Neoplasia 7 2 99 108
-
(2005)
Neoplasia
, vol.7
, pp. 99-108
-
-
Thorstensen, L.1
Lind, G.E.2
Løvig, T.3
-
26
-
-
0036022107
-
Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancers
-
1
-
T Furukawa F Konishi S Masubuchi 2002 Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancers Genes Chromosomes Cancer 35 1 1 10
-
(2002)
Genes Chromosomes Cancer
, vol.35
, pp. 1-10
-
-
Furukawa, T.1
Konishi, F.2
Masubuchi, S.3
-
27
-
-
33846525014
-
Phenotypes of invasion in sporadic colorectal carcinomas related to aberrations of the adenomatous polyposis coli (APC) gene
-
3
-
F Prall V Weirich C Ostwald 2007 Phenotypes of invasion in sporadic colorectal carcinomas related to aberrations of the adenomatous polyposis coli (APC) gene Histopathology 50 3 318 330
-
(2007)
Histopathology
, vol.50
, pp. 318-330
-
-
Prall, F.1
Weirich, V.2
Ostwald, C.3
-
28
-
-
0032823133
-
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: A new facet to Knudson's 'two-hit' hypothesis
-
9
-
H Lamlum M Ilyas A Rowan 1999 The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis Nat Med 5 9 1071 1075
-
(1999)
Nat Med
, vol.5
, pp. 1071-1075
-
-
Lamlum, H.1
Ilyas, M.2
Rowan, A.3
-
29
-
-
16944365288
-
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC
-
1
-
SJ Laken GM Petersen SB Gruber 1997 Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC Nat Genet 17 1 79 83
-
(1997)
Nat Genet
, vol.17
, pp. 79-83
-
-
Laken, S.J.1
Petersen, G.M.2
Gruber, S.B.3
-
30
-
-
26844479501
-
Rare mutations predisposing to familial adenomatous polyposis in Greek FAP patients
-
1
-
M Mihalatos A Apessos H Dauwerse 2005 Rare mutations predisposing to familial adenomatous polyposis in Greek FAP patients BMC Cancer 5 1 40 47
-
(2005)
BMC Cancer
, vol.5
, pp. 40-47
-
-
Mihalatos, M.1
Apessos, A.2
Dauwerse, H.3
-
31
-
-
0037389343
-
Genetic analysis of familial colorectal cancer in Israeli Arabs
-
4
-
R Chen-Shtoyerman L Theodor E Harmati 2003 Genetic analysis of familial colorectal cancer in Israeli Arabs Hum Mutat 21 4 446 447
-
(2003)
Hum Mutat
, vol.21
, pp. 446-447
-
-
Chen-Shtoyerman, R.1
Theodor, L.2
Harmati, E.3
-
32
-
-
19044395448
-
Molecular analysis of the APC gene in 71 Israeli families: 17 novel mutations
-
6
-
N Gavert Y Yaron T Naiman 2002 Molecular analysis of the APC gene in 71 Israeli families: 17 novel mutations Hum Mutat 19 6 664
-
(2002)
Hum Mutat
, vol.19
, pp. 664
-
-
Gavert, N.1
Yaron, Y.2
Naiman, T.3
-
33
-
-
0027320554
-
Identical APC exon 15 mutations result in a variable phenotype in familial adenomatous polyposis
-
7
-
P Paul T Letteboer L Gelbert 1993 Identical APC exon 15 mutations result in a variable phenotype in familial adenomatous polyposis Hum Mol Genet 2 7 925 931
-
(1993)
Hum Mol Genet
, vol.2
, pp. 925-931
-
-
Paul, P.1
Letteboer, T.2
Gelbert, L.3
-
34
-
-
33646147162
-
Novel germline mutations in the APC gene of Cypriot patients with familial and sporadic adenomatous polyposis
-
5
-
A Hadjisavvas T Papasavva M Loizidou 2006 Novel germline mutations in the APC gene of Cypriot patients with familial and sporadic adenomatous polyposis Clin Genet 69 5 404 409
-
(2006)
Clin Genet
, vol.69
, pp. 404-409
-
-
Hadjisavvas, A.1
Papasavva, T.2
Loizidou, M.3
-
35
-
-
34548472447
-
How the I1307K adenomatous polyposis coli gene variant contributes in the assessment of risk of colorectal cancer, but not stomach cancer, in a Turkish population
-
2
-
M Dundar AO Caglayan C Saatci 2007 How the I1307K adenomatous polyposis coli gene variant contributes in the assessment of risk of colorectal cancer, but not stomach cancer, in a Turkish population Cancer Genet Cytogenet 177 2 95 97
-
(2007)
Cancer Genet Cytogenet
, vol.177
, pp. 95-97
-
-
Dundar, M.1
Caglayan, A.O.2
Saatci, C.3
-
36
-
-
33845607724
-
Promoter methylation precedes chromosomal alterations in colorectal cancer development
-
5-6
-
S Derks C Postma PT Moerkerk 2006 Promoter methylation precedes chromosomal alterations in colorectal cancer development Cell Oncol 28 5-6 247 527
-
(2006)
Cell Oncol
, vol.28
, pp. 247-527
-
-
Derks, S.1
Postma, C.2
Moerkerk, P.T.3
-
37
-
-
33846192840
-
The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer
-
1
-
A Goel T Nagasaka CN Arnold 2007 The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer Gastroenterology 132 1 127 138
-
(2007)
Gastroenterology
, vol.132
, pp. 127-138
-
-
Goel, A.1
Nagasaka, T.2
Arnold, C.N.3
-
38
-
-
33947259556
-
APC mutations and other genetic and epigenetic changes in colon cancer
-
2
-
WS Samowitz ML Slattery C Sweeney 2007 APC mutations and other genetic and epigenetic changes in colon cancer Mol Cancer Res 5 2 165 170
-
(2007)
Mol Cancer Res
, vol.5
, pp. 165-170
-
-
Samowitz, W.S.1
Slattery, M.L.2
Sweeney, C.3
-
39
-
-
18644370130
-
Mutations of the APC gene in human sporadic colorectal cancers
-
9
-
C De Filippo C Luceri G Caderni 2002 Mutations of the APC gene in human sporadic colorectal cancers Scand J Gastroenterol 37 9 1048 1053
-
(2002)
Scand J Gastroenterol
, vol.37
, pp. 1048-1053
-
-
De Filippo, C.1
Luceri, C.2
Caderni, G.3
|