Genome-wide linkage analysis and tumoral characterization reveal heterogeneity in familial colorectal cancer type X

Journal of Gastroenterology

Volumn 50, Issue 6, 2015, Pages 657-666

  Sanchez Tome E ^a   Rivera, B ^a   Perea, J ^b   Pita, G ^a   Rueda, D ^b   Mercadillo, F ^a   Canal, A ^b   Gonzalez Neira, A ^a   Benitez, J ^a,c   Urioste, M ^a,c  

^a Structural Biology and Biocomputing Programme   (Spain)

^b HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

Author keywords

Chromosomal instability (CIN); CpG island methylator phenotype (CIMP); Familial colorectal cancer type X (FCCTX); Linkage analysis; Tissue microarray (TMA)

Indexed keywords

B RAF KINASE; BETA CATENIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN; MUCIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6; PROTEIN P21; PROTEIN P53; SMAD4 PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; UVOMORULIN; BRAF PROTEIN, HUMAN; KRAS PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CHROMOSOMAL INSTABILITY; COLORECTAL TUMOR; CONTROLLED STUDY; CPG ISLAND; FAMILIAL COLORECTAL CANCER TYPE X; GENE MUTATION; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENOTYPE; HEREDITARY COLORECTAL CANCER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE MICROARRAY; WNT SIGNALING PATHWAY; GENETIC LINKAGE; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; MIDDLE AGED; MUTATION; PATHOLOGY; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; CHROMOSOMAL INSTABILITY; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; CPG ISLANDS; GENETIC LINKAGE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MIDDLE AGED; MUTATION; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS P21(RAS); YOUNG ADULT;

EID: 84930757295     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-014-1009-0     Document Type: Article

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