Somatic hypermethylation of MSH2 is a frequent event in Lynch syndrome colorectal cancers

Cancer Research

Volumn 70, Issue 8, 2010, Pages 3098-3108

  Nagasaka, Takeshi ^a,b   Rhees, Jennifer ^a   Kloor, Matthias ^c   Gebert, Johannes ^c   Naomoto, Yoshio ^b   Boland, C Richard ^a   Goel, Ajay ^a  

^a BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^b OKAYAMA UNIVERSITY   (Japan)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; PROTEIN MSH2;

ALLELE; ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; CPG ISLAND; FAMILIAL CANCER; GENE; GENE DELETION; GENE MUTATION; HUMAN; HUMAN TISSUE; METHYLATION; MICROSATELLITE INSTABILITY; MSH2 GENE; ONCOGENE K RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOMATIC MUTATION;

COHORT STUDIES; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; GERM-LINE MUTATION; HUMANS; MICROSATELLITE REPEATS; MODELS, GENETIC; MUTATION; MUTS HOMOLOG 2 PROTEIN; PHENOTYPE; PROTO-ONCOGENE PROTEINS B-RAF;

EID: 77951049336     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-3290     Document Type: Article

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