Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion

Molecular Cancer

Volumn 12, Issue 1, 2013, Pages

  Sengupta, Neel ^a   Yau, Christopher ^b   Sakthianandeswaren, Anuratha ^c   Mouradov, Dmitri ^c   Gibbs, Peter ^c   Suraweera, Nirosha ^a   Cazier, Jean Baptiste ^d   Polanco Echeverry, Guadalupe ^a,d   Ghosh, Anil ^a   Thaha, Mohamed ^a,e   Ahmed, Shafi ^e   Feakins, Roger ^e   Propper, David ^f   Dorudi, Sina ^a   Sieber, Oliver ^c,g   Silver, Andrew ^a   Lai, Cecilia ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (Australia)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e ROYAL LONDON HOSPITAL   (United Kingdom)

^f ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^g UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

BRAF; British Bangladeshi; Colorectal cancer; Genome analysis; KRAS; RBFOX1

Indexed keywords

K RAS PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; RBFOX1 PROTEIN; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER STAGING; CHROMOSOME 16P; CHROMOSOME 17P; CHROMOSOME 18Q; CHROMOSOME 7; CHROMOSOME 8P; CHROMOSOME 8Q; CHROMOSOME ANALYSIS; CHROMOSOME DELETION; CHROMOSOME LOSS; CLINICAL ARTICLE; CLINICAL FEATURE; CODON; COLORECTAL CANCER; CONTROLLED STUDY; COPY NUMBER VARIATION; CORRELATION ANALYSIS; FEMALE; GENE DELETION; GENE IDENTIFICATION; GENOME ANALYSIS; GENOTYPE; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MICROSATELLITE INSTABILITY; MUTATIONAL ANALYSIS; ONSET AGE; PREVALENCE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADENOCARCINOMA, MUCINOUS; ADULT; AGED; AGED, 80 AND OVER; BANGLADESH; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE DELETION; GENE DOSAGE; GREAT BRITAIN; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; RAS PROTEINS; RNA-BINDING PROTEINS; YOUNG ADULT;

EID: 84871720551     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-12-1     Document Type: Article

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