Germline hypermethylation of the APC promoter is not a frequent cause of familial adenomatous polyposis in APC/MUTYH mutation negative families

International Journal of Cancer

Volumn 122, Issue 6, 2008, Pages 1422-1425

  Romero Giménez, Jordi ^a   Dopeso, Higinio ^a   Blanco, Ignacio ^b   Guerra Moreno, Angel ^a   Gonzalez, Sara ^b   Vogt, Stefanie ^c   Aretz, Stefan ^c   Schwartz Jr , Simo ^a   Capella, Gabriel ^b   Arango, Diego ^a  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^c UNIVERSITY OF BONN   (Germany)

Author keywords

AFAP; APC; Colorectal cancer; FAP; Promoter methylation

Indexed keywords

APC; BISULFITE; DINUCLEOTIDE; DNA GLYCOSYLASE MUTY;

ADENOMATOUS POLYP; ADULT; AGED; ARTICLE; CANCER SUSCEPTIBILITY; COLON CARCINOGENESIS; COLORECTAL TUMOR; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; DNA METHYLATION; EPIGENETICS; FAMILIAL CANCER; FEMALE; GENE LOSS; GENE MUTATION; GENE SEQUENCE; GENE SILENCING; GENETIC SUSCEPTIBILITY; GERM LINE; HUMAN; INHERITANCE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; TUMOR SUPPRESSOR GENE;

ADENOMATOUS POLYPOSIS COLI; BASE SEQUENCE; CPG ISLANDS; DNA GLYCOSYLASES; DNA METHYLATION; DNA PRIMERS; GENES, APC; GERM-LINE MUTATION; HUMANS; PROMOTER REGIONS (GENETICS);

EID: 39649123486     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23247     Document Type: Article

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