Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-xL in addition to Bax and p53 status

International Journal of Cancer

Volumn 98, Issue 4, 2002, Pages 498-504

  Violette, Sabine ^a   Poulain, Laurent ^b   Dussaulx, Elisabeth ^a   Pepin, Dominique ^c   Faussat, Anne Marie ^c   Chambaz, Jean ^a,c   Lacorte, Jean Marc ^a,c   Staedel, Cathy ^b   Lesuffleur, Thécla ^a  

^a INSERM   (France)

^b François Baclesse Anticancer Research Institute   (France)

^c HÔTEL DIEU   (France)

Author keywords

5 FU resistance; Bcl 2 and Bcl xLexpression; Colon cancer cells; p53 and bax status

Indexed keywords

BIOCHEMICAL MARKER; FLUOROURACIL; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53;

ACCURACY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL FUNCTION; CELL LEVEL; COLON CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EXPOSURE; GENOTYPE; HUMAN; HUMAN CELL; LONG TERM CARE; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION;

ANTIMETABOLITES, ANTINEOPLASTIC; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BLOTTING, WESTERN; COLONIC NEOPLASMS; DRUG RESISTANCE, NEOPLASM; FLUOROURACIL; GENOTYPE; HT29 CELLS; HUMANS; MUTATION; PHENOTYPE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TIME FACTORS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036533524     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10146     Document Type: Article

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