메뉴 건너뛰기




Volumn 39, Issue 3, 2015, Pages 313-317

Sporadic microsatellite instability-high colon cancers rarely display immunohistochemical evidence of Wnt signaling activation

Author keywords

APC; BRAF; serrated neoplastic pathway; sessile serrated polyp; catenin

Indexed keywords

ADENOSINE TRIPHOSPHATASE; B RAF KINASE; BETA CATENIN; BRAF PROTEIN, HUMAN; CTNNB1 PROTEIN, HUMAN; DNA BINDING PROTEIN; MLH1 PROTEIN, HUMAN; NUCLEAR PROTEIN; PMS2 PROTEIN, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR MARKER;

EID: 84924049990     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0000000000000380     Document Type: Article
Times cited : (29)

References (21)
  • 1
    • 0027738023 scopus 로고
    • Association of the APC gene product with beta-catenin
    • Rubinfeld B, Souza B, Albert I, et al. Association of the APC gene product with beta-catenin. Science. 1993;262:1731-1734.
    • (1993) Science , vol.262 , pp. 1731-1734
    • Rubinfeld, B.1    Souza, B.2    Albert, I.3
  • 2
    • 0027756014 scopus 로고
    • Association of the APC tumor suppressor protein with catenins
    • Su LK, Vogelstein B, Kinzler KW. Association of the APC tumor suppressor protein with catenins. Science. 1993;262:1734-1737.
    • (1993) Science , vol.262 , pp. 1734-1737
    • Su, L.K.1    Vogelstein, B.2    Kinzler, K.W.3
  • 3
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • Morin PJ, Sparks AB, Korinek V, et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science. 1997;275:1787-1790.
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3
  • 4
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumor development
    • Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development.NEngl J Med. 1988;319:525-532.
    • (1988) NEngl J Med , vol.319 , pp. 525-532
    • Vogelstein, B.1    Fearon, E.R.2    Hamilton, S.R.3
  • 5
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • Muzny DM, Bainbridge MN, Chang K, et al. Comprehensive molecular characterization of human colon and rectal cancer. Nature. 2012;487:330-337.
    • (2012) Nature , vol.487 , pp. 330-337
    • Muzny, D.M.1    Bainbridge, M.N.2    Chang, K.3
  • 6
    • 13244264729 scopus 로고    scopus 로고
    • Progressive methylation during the serrated neoplasia pathway of the colorectum
    • Dong SM, Lee EJ, Jeon ES, et al. Progressive methylation during the serrated neoplasia pathway of the colorectum. Mod Pathol. 2005;18:170-178.
    • (2005) Mod Pathol , vol.18 , pp. 170-178
    • Dong, S.M.1    Lee, E.J.2    Jeon, E.S.3
  • 7
    • 2442568714 scopus 로고    scopus 로고
    • Molecular differences between sporadic serrated and conventional colorectal adenomas
    • Konishi K, Yamochi T, Makino R, et al. Molecular differences between sporadic serrated and conventional colorectal adenomas. Clin Cancer Res. 2004;10:3082-3090.
    • (2004) Clin Cancer Res , vol.10 , pp. 3082-3090
    • Konishi, K.1    Yamochi, T.2    Makino, R.3
  • 8
    • 0042941629 scopus 로고    scopus 로고
    • BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas
    • Chan TL, Zhao W, Leung SY, et al. BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas. Cancer Res. 2003;63:4878-4881.
    • (2003) Cancer Res , vol.63 , pp. 4878-4881
    • Chan, T.L.1    Zhao, W.2    Leung, S.Y.3
  • 9
    • 57349089198 scopus 로고    scopus 로고
    • Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps
    • Kim YH, Kakar S, Cun L, et al. Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps. Int J Cancer. 2008;123:2587-2593.
    • (2008) Int J Cancer , vol.123 , pp. 2587-2593
    • Kim, Y.H.1    Kakar, S.2    Cun, L.3
  • 10
    • 0035185894 scopus 로고    scopus 로고
    • Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: Parallel pathways of tumorigenesis
    • Young J, Simms LA, Biden KG, et al. Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis. Am J Pathol. 2001;159:2107-2116.
    • (2001) Am J Pathol , vol.159 , pp. 2107-2116
    • Young, J.1    Simms, L.A.2    Biden, K.G.3
  • 11
    • 1642535480 scopus 로고    scopus 로고
    • BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer
    • Deng G, Bell I, Crawley S, et al. BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer. Clin Cancer Res. 2004;10:191-195.
    • (2004) Clin Cancer Res , vol.10 , pp. 191-195
    • Deng, G.1    Bell, I.2    Crawley, S.3
  • 12
    • 0037372340 scopus 로고    scopus 로고
    • Frequent CpG island methylation in serrated adenomas of the colorectum
    • Park SJ, Rashid A, Lee JH, et al. Frequent CpG island methylation in serrated adenomas of the colorectum. Am J Pathol. 2003;162: 815-822.
    • (2003) Am J Pathol , vol.162 , pp. 815-822
    • Park, S.J.1    Rashid, A.2    Lee, J.H.3
  • 13
    • 33750682008 scopus 로고    scopus 로고
    • High prevalence of sessile serrated adenomas with BRAF mutations: A prospective study of patients undergoing colonoscopy
    • Spring KJ, Zhao ZZ, Karamatic R, et al. High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy. Gastroenterology. 2006;131: 1400-1407.
    • (2006) Gastroenterology , vol.131 , pp. 1400-1407
    • Spring, K.J.1    Zhao, Z.Z.2    Karamatic, R.3
  • 14
    • 41649102270 scopus 로고    scopus 로고
    • Frequent betacatenin nuclear labeling in sessile serrated polyps of the colorectum with neoplastic potential
    • Wu JM, Montgomery EA, Iacobuzio-Donahue CA. Frequent betacatenin nuclear labeling in sessile serrated polyps of the colorectum with neoplastic potential. Am J Clin Pathol. 2008;129:416-423.
    • (2008) Am J Clin Pathol , vol.129 , pp. 416-423
    • Wu, J.M.1    Montgomery, E.A.2    Iacobuzio-Donahue, C.A.3
  • 15
    • 73349134675 scopus 로고    scopus 로고
    • Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation
    • Yachida S, Mudali S, Martin SA, et al. Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation. Am J Surg Pathol. 2009;33:1823-1832.
    • (2009) Am J Surg Pathol , vol.33 , pp. 1823-1832
    • Yachida, S.1    Mudali, S.2    Martin, S.A.3
  • 18
    • 0037249071 scopus 로고    scopus 로고
    • APC mutation and tumour budding in colorectal cancer
    • Jass JR, Barker M, Fraser L, et al. APC mutation and tumour budding in colorectal cancer. J Clin Pathol. 2003;56:69-73.
    • (2003) J Clin Pathol , vol.56 , pp. 69-73
    • Jass, J.R.1    Barker, M.2    Fraser, L.3
  • 19
    • 33947259556 scopus 로고    scopus 로고
    • APC mutations and other genetic and epigenetic changes in colon cancer
    • Samowitz WS, Slattery ML, Sweeney C, et al. APC mutations and other genetic and epigenetic changes in colon cancer. Mol Cancer Res. 2007;5:165-170.
    • (2007) Mol Cancer Res , vol.5 , pp. 165-170
    • Samowitz, W.S.1    Slattery, M.L.2    Sweeney, C.3
  • 20
    • 0010945939 scopus 로고    scopus 로고
    • APC mutations in colorectal tumors with mismatch repair deficiency
    • Huang J, Papadopoulos N, McKinley AJ, et al. APC mutations in colorectal tumors with mismatch repair deficiency. Proc Natl Acad Sci USA. 1996;93:9049-9054.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9049-9054
    • Huang, J.1    Papadopoulos, N.2    McKinley, A.J.3
  • 21
    • 84872842789 scopus 로고    scopus 로고
    • MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes
    • Donehower LA, Creighton CJ, Schultz N, et al. MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes. J Pathol. 2013;229:99-110.
    • (2013) J Pathol , vol.229 , pp. 99-110
    • Donehower, L.A.1    Creighton, C.J.2    Schultz, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.