Mechanisms of inactivation of MLH1 in hereditary nonpolyposis colorectal carcinoma: A novel approach

Oncogene

Volumn 26, Issue 31, 2007, Pages 4541-4549

  Ollikainen, M ^a   Hannelius, U ^b   Lindgren, C M ^b   Abdel Rahman, W M ^a   Kere, J ^a,b   Peltomaki P ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Colorectal cancer; Endometrial cancer; Hereditary nonpolyposis colorectal cancer; Loss of heterozygosity; Promoter methylation

Indexed keywords

PROTEIN MLH1;

ALLELE; ARTICLE; CANCER SUSCEPTIBILITY; COLORECTAL CARCINOMA; CONTROLLED STUDY; ENDOMETRIUM CANCER; GENE DELETION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METHYLATION; MISSENSE MUTATION; MUTATION; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; COHORT STUDIES; COLORECTAL NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; CPG ISLANDS; DNA METHYLATION; DNA MISMATCH REPAIR; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; LOSS OF HETEROZYGOSITY; MUTATION; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 34447132378     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210236     Document Type: Article

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