메뉴 건너뛰기




Volumn 4, Issue 2, 2016, Pages

Direct delivery of antigens to dendritic cells via antibodies specific for endocytic receptors as a promising strategy for future therapies

Author keywords

Antigen targeting; Antigen targeting antibodies; Cancer; CLR; DC; DCIR; DEC205; Dendritic cell subsets; moDC; Vaccine

Indexed keywords

ANTIGEN; CD103 ANTIGEN; CD11B ANTIGEN; CELL RECEPTOR; DECTIN 1; ENDOCYTIC RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; LANGERIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PATHOGEN ASSOCIATED MOLECULAR PATTERN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 11; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

EID: 85009388464     PISSN: None     EISSN: 2076393X     Source Type: Journal    
DOI: 10.3390/vaccines4020008     Document Type: Review
Times cited : (66)

References (267)
  • 2
    • 36248965712 scopus 로고    scopus 로고
    • Dendritic cells: Understanding immunogenicity
    • Steinman, R.M. Dendritic cells: Understanding immunogenicity. Eur. J. Immunol. 2007.
    • (2007) Eur. J. Immunol
    • Steinman, R.M.1
  • 6
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
    • Steinman, R.M.; Nussenzweig, M.C. Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance. Proc. Nat. Acad. Sci. USA 2002, 99, 351–358.
    • (2002) Proc. Nat. Acad. Sci. USA , vol.99 , pp. 351-358
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 9
    • 79953756066 scopus 로고    scopus 로고
    • Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses
    • Hammad, H.; Lambrecht, B.N. Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses. Allergy 2011, 66, 579–587.
    • (2011) Allergy , vol.66 , pp. 579-587
    • Hammad, H.1    Lambrecht, B.N.2
  • 10
    • 58049209834 scopus 로고    scopus 로고
    • Inflammatory signals in dendritic cell activation and the induction of adaptive immunity
    • Joffre, O.; Nolte, M.A.; Sporri, R.; Reis e Sousa, C. Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol. Rev. 2009, 227, 234–247.
    • (2009) Immunol. Rev , vol.227 , pp. 234-247
    • Joffre, O.1    Nolte, M.A.2    Sporri, R.3    Reis E Sousa, C.4
  • 11
    • 84875528275 scopus 로고    scopus 로고
    • The dendritic cell lineage: Ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting
    • Merad, M.; Sathe, P.; Helft, J.; Miller, J.; Mortha, A. The dendritic cell lineage: Ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Ann. Rev. Immunol. 2013, 31, 563–604.
    • (2013) Ann. Rev. Immunol , vol.31 , pp. 563-604
    • Merad, M.1    Sathe, P.2    Helft, J.3    Miller, J.4    Mortha, A.5
  • 12
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J.; Steinman, R.M. Dendritic cells and the control of immunity. Nature 1998, 392, 245–252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 13
    • 0036518287 scopus 로고    scopus 로고
    • Mouse and human dendritic cell subtypes
    • Shortman, K.; Liu, Y.J. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2002, 2, 151–161.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 151-161
    • Shortman, K.1    Liu, Y.J.2
  • 14
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira, S.; Uematsu, S.; Takeuchi, O. Pathogen recognition and innate immunity. Cell 2006, 124, 783–801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 15
    • 0033861419 scopus 로고    scopus 로고
    • The interleukin-1 receptor/toll-like receptor superfamily: Signal generators for pro-inflammatory interleukins and microbial products
    • Bowie, A.; O’Neill, L.A. The interleukin-1 receptor/toll-like receptor superfamily: Signal generators for pro-inflammatory interleukins and microbial products. J. Leukoc. Biol. 2000, 67, 508–514.
    • (2000) J. Leukoc. Biol , vol.67 , pp. 508-514
    • Bowie, A.1    O’Neill, L.A.2
  • 16
    • 84889654582 scopus 로고    scopus 로고
    • Nucleic acids and endosomal pattern recognition: How to tell friend from foe?
    • Brencicova, E.; Diebold, S.S. Nucleic acids and endosomal pattern recognition: How to tell friend from foe? Front. Cell. Infect. Microbiol. 2013.
    • (2013) Front. Cell. Infect. Microbiol
    • Brencicova, E.1    Diebold, S.S.2
  • 17
    • 0141533076 scopus 로고    scopus 로고
    • Dual function of C-type lectin-like receptors in the immune system
    • Cambi, A.; Figdor, C.G. Dual function of C-type lectin-like receptors in the immune system. Curr. Opin. Cell Biol. 2003, 15, 539–546.
    • (2003) Curr. Opin. Cell Biol , vol.15 , pp. 539-546
    • Cambi, A.1    Figdor, C.G.2
  • 18
    • 0036481121 scopus 로고    scopus 로고
    • C-type lectin receptors on dendritic cells and langerhans cells
    • Figdor, C.G.; van Kooyk, Y.; Adema, G.J. C-type lectin receptors on dendritic cells and langerhans cells. Nat. Rev. Immunol. 2002, 2, 77–84.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 77-84
    • Figdor, C.G.1    Van Kooyk, Y.2    Adema, G.J.3
  • 20
    • 64049090893 scopus 로고    scopus 로고
    • Antigen presentation by dendritic cells in vivo
    • Segura, E.; Villadangos, J.A. Antigen presentation by dendritic cells in vivo. Curr. Opin. Immunol. 2009, 21, 105–110.
    • (2009) Curr. Opin. Immunol , vol.21 , pp. 105-110
    • Segura, E.1    Villadangos, J.A.2
  • 21
    • 84937967684 scopus 로고    scopus 로고
    • The multifaceted biology of plasmacytoid dendritic cells
    • Swiecki, M.; Colonna, M. The multifaceted biology of plasmacytoid dendritic cells. Nat. Rev. Immunol. 2015, 15, 471–485.
    • (2015) Nat. Rev. Immunol , vol.15 , pp. 471-485
    • Swiecki, M.1    Colonna, M.2
  • 22
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi, O.; Akira, S. Pattern recognition receptors and inflammation. Cell 2010, 140, 805–820.
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 24
    • 49649109586 scopus 로고    scopus 로고
    • Dual signaling of MyD88 and trif is critical for maximal TLR4-induced dendritic cell maturation
    • Shen, H.; Tesar, B.M.; Walker, W.E.; Goldstein, D.R. Dual signaling of MyD88 and trif is critical for maximal TLR4-induced dendritic cell maturation. J. Immunol. 2008, 181, 1849–1858.
    • (2008) J. Immunol , vol.181 , pp. 1849-1858
    • Shen, H.1    Tesar, B.M.2    Walker, W.E.3    Goldstein, D.R.4
  • 25
    • 0038491296 scopus 로고    scopus 로고
    • Presentation of exogenous antigens on major histocompatibility complex (MHC) class I andMHCclass II molecules is differentially regulated during dendritic cell maturation
    • Delamarre, L.; Holcombe, H.; Mellman, I. Presentation of exogenous antigens on major histocompatibility complex (MHC) class I andMHCclass II molecules is differentially regulated during dendritic cell maturation. J. Exp. Med. 2003, 198, 111–122.
    • (2003) J. Exp. Med , vol.198 , pp. 111-122
    • Delamarre, L.1    Holcombe, H.2    Mellman, I.3
  • 26
    • 34250347630 scopus 로고    scopus 로고
    • The contribution of immunology to the rational design of novel antibacterial vaccines. Nat
    • Kaufmann, S.H. The contribution of immunology to the rational design of novel antibacterial vaccines. Nat. Rev. Microbiol. 2007, 5, 491–504.
    • (2007) Rev. Microbiol , vol.5 , pp. 491-504
    • Kaufmann, S.H.1
  • 27
    • 56749133272 scopus 로고    scopus 로고
    • Viral evasion and subversion of pattern-recognition receptor signalling
    • Bowie, A.G.; Unterholzner, L. Viral evasion and subversion of pattern-recognition receptor signalling. Nat. Rev. Immunol. 2008, 8, 911–922.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 911-922
    • Bowie, A.G.1    Unterholzner, L.2
  • 28
    • 70449590867 scopus 로고    scopus 로고
    • Discovery and classification of glycan-binding proteins
    • 2nd ed.; Varki, A., Cummings, R.D., Esko, J.D., Freeze, H.H., Stanley, P., Bertozzi, C.R., Hart, G.W., Etzler, M.E., Eds.; Cold Spring Harbor: New York, NY, USA
    • Varki, A.; Etzler, M.E.; Cummings, R.D.; Esko, J.D. Discovery and classification of glycan-binding proteins. In Essentials of Glycobiology, 2nd ed.; Varki, A., Cummings, R.D., Esko, J.D., Freeze, H.H., Stanley, P., Bertozzi, C.R., Hart, G.W., Etzler, M.E., Eds.; Cold Spring Harbor: New York, NY, USA, 2009.
    • (2009) Essentials of Glycobiology
    • Varki, A.1    Etzler, M.E.2    Cummings, R.D.3    Esko, J.D.4
  • 29
    • 67649840704 scopus 로고    scopus 로고
    • Signalling through C-type lectin receptors: Shaping immune responses. Nat
    • Geijtenbeek, T.B.; Gringhuis, S.I. Signalling through C-type lectin receptors: Shaping immune responses. Nat. Rev. Immunol. 2009, 9, 465–479.
    • (2009) Rev. Immunol , vol.9 , pp. 465-479
    • Geijtenbeek, T.B.1    Gringhuis, S.I.2
  • 30
    • 44049095632 scopus 로고    scopus 로고
    • Protein-glycan interactions in the control of innate and adaptive immune responses
    • Van Kooyk, Y.; Rabinovich, G.A. Protein-glycan interactions in the control of innate and adaptive immune responses. Nat. Immunol. 2008, 9, 593–601.
    • (2008) Nat. Immunol , vol.9 , pp. 593-601
    • Van Kooyk, Y.1    Rabinovich, G.A.2
  • 32
    • 84859037979 scopus 로고    scopus 로고
    • Sterile inflammatory response in acute pancreatitis
    • Hoque, R.; Malik, A.F.; Gorelick, F.; Mehal, W.Z. Sterile inflammatory response in acute pancreatitis. Pancreas 2012, 41, 353–357.
    • (2012) Pancreas , vol.41 , pp. 353-357
    • Hoque, R.1    Malik, A.F.2    Gorelick, F.3    Mehal, W.Z.4
  • 33
    • 84862835766 scopus 로고    scopus 로고
    • Degraded mitochondrial DNA is a newly identified subtype of the damage associated molecular pattern (DAMP) family and possible trigger of neurodegeneration
    • Mathew, A.; Lindsley, T.A.; Sheridan, A.; Bhoiwala, D.L.; Hushmendy, S.F.; Yager, E.J.; Ruggiero, E.A.; Crawford, D.R. Degraded mitochondrial DNA is a newly identified subtype of the damage associated molecular pattern (DAMP) family and possible trigger of neurodegeneration. J. Alzheimers Dis. 2012, 30, 617–627.
    • (2012) J. Alzheimers Dis , vol.30 , pp. 617-627
    • Mathew, A.1    Lindsley, T.A.2    Sheridan, A.3    Bhoiwala, D.L.4    Hushmendy, S.F.5    Yager, E.J.6    Ruggiero, E.A.7    Crawford, D.R.8
  • 35
    • 84899883247 scopus 로고    scopus 로고
    • Translating drips: MHC class I immunosurveillance of pathogens and tumors
    • Anton, L.C.; Yewdell, J.W. Translating drips: MHC class I immunosurveillance of pathogens and tumors. J. Leukoc. Biol. 2014, 95, 551–562.
    • (2014) J. Leukoc. Biol , vol.95 , pp. 551-562
    • Anton, L.C.1    Yewdell, J.W.2
  • 36
    • 0036715411 scopus 로고    scopus 로고
    • Immature, semi-mature and fully mature dendritic cells: Which signals induce tolerance or immunity?
    • Lutz, M.B.; Schuler, G. Immature, semi-mature and fully mature dendritic cells: Which signals induce tolerance or immunity? Trends Immunol. 2002, 23, 445–449.
    • (2002) Trends Immunol , vol.23 , pp. 445-449
    • Lutz, M.B.1    Schuler, G.2
  • 37
    • 0024372111 scopus 로고
    • Acquisition of immunologic self-tolerance
    • Schwartz, R.H. Acquisition of immunologic self-tolerance. Cell 1989, 57, 1073–1081.
    • (1989) Cell , vol.57 , pp. 1073-1081
    • Schwartz, R.H.1
  • 38
    • 79953834363 scopus 로고    scopus 로고
    • Current status and future applications of cellular therapies for cancer
    • Copier, J.; Bodman-Smith, M.; Dalgleish, A. Current status and future applications of cellular therapies for cancer. Immunotherapy 2011, 3, 507–516.
    • (2011) Immunotherapy , vol.3 , pp. 507-516
    • Copier, J.1    Bodman-Smith, M.2    Dalgleish, A.3
  • 40
    • 84928468391 scopus 로고    scopus 로고
    • Precision cancer immunotherapy: Optimizing dendritic cell-based strategies to induce tumor antigen-specific t-cell responses against individual patient tumors
    • Osada, T.; Nagaoka, K.; Takahara, M.; Yang, X.Y.; Liu, C.X.; Guo, H.; Roy Choudhury, K.; Hobeika, A.; Hartman, Z.; Morse, M.A.; et al. Precision cancer immunotherapy: Optimizing dendritic cell-based strategies to induce tumor antigen-specific t-cell responses against individual patient tumors. J. Immunother. 2015, 38, 155–164.
    • (2015) J. Immunother , vol.38 , pp. 155-164
    • Osada, T.1    Nagaoka, K.2    Takahara, M.3    Yang, X.Y.4    Liu, C.X.5    Guo, H.6    Roy Choudhury, K.7    Hobeika, A.8    Hartman, Z.9    Morse, M.A.10
  • 41
    • 84858780815 scopus 로고    scopus 로고
    • Cancer immunotherapy via dendritic cells
    • Palucka, K.; Banchereau, J. Cancer immunotherapy via dendritic cells. Nat. Rev. Cancer 2012, 12, 265–277.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 265-277
    • Palucka, K.1    Banchereau, J.2
  • 43
    • 79952440284 scopus 로고    scopus 로고
    • Targeted antigen delivery and activation of dendritic cells in vivo: Steps towards cost effective vaccines
    • Tacken, P.J.; Figdor, C.G. Targeted antigen delivery and activation of dendritic cells in vivo: Steps towards cost effective vaccines. Semin. Immunol. 2011, 23, 12–20.
    • (2011) Semin. Immunol , vol.23 , pp. 12-20
    • Tacken, P.J.1    Figdor, C.G.2
  • 44
    • 34848837386 scopus 로고    scopus 로고
    • Taking dendritic cells into medicine
    • Steinman, R.M.; Banchereau, J. Taking dendritic cells into medicine. Nature 2007, 449, 419–426.
    • (2007) Nature , vol.449 , pp. 419-426
    • Steinman, R.M.1    Banchereau, J.2
  • 45
    • 2642631750 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions
    • Jonuleit, H.; Kuhn, U.; Muller, G.; Steinbrink, K.; Paragnik, L.; Schmitt, E.; Knop, J.; Enk, A.H. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur. J. Immunol. 1997, 27, 3135–3142.
    • (1997) Eur. J. Immunol , vol.27 , pp. 3135-3142
    • Jonuleit, H.1    Kuhn, U.2    Muller, G.3    Steinbrink, K.4    Paragnik, L.5    Schmitt, E.6    Knop, J.7    Enk, A.H.8
  • 46
    • 0024549594 scopus 로고
    • Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal langerhans cells
    • Romani, N.; Koide, S.; Crowley, M.; Witmer-Pack, M.; Livingstone, A.M.; Fathman, C.G.; Inaba, K.; Steinman, R.M. Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal langerhans cells. J. Exp. Med. 1989, 169, 1169–1178.
    • (1989) J. Exp. Med , vol.169 , pp. 1169-1178
    • Romani, N.1    Koide, S.2    Crowley, M.3    Witmer-Pack, M.4    Livingstone, A.M.5    Fathman, C.G.6    Inaba, K.7    Steinman, R.M.8
  • 47
    • 0029148878 scopus 로고
    • Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: Downregulation by cytokines and bacterial products
    • Sallusto, F.; Cella, M.; Danieli, C.; Lanzavecchia, A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: Downregulation by cytokines and bacterial products. J. Exp. Med. 1995, 182, 389–400.
    • (1995) J. Exp. Med , vol.182 , pp. 389-400
    • Sallusto, F.1    Cella, M.2    Danieli, C.3    Lanzavecchia, A.4
  • 48
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
    • Sallusto, F.; Lanzavecchia, A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 1994, 179, 1109–1118.
    • (1994) J. Exp. Med. , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 49
    • 0037141023 scopus 로고    scopus 로고
    • Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells
    • Schuler-Thurner, B.; Schultz, E.S.; Berger, T.G.; Weinlich, G.; Ebner, S.; Woerl, P.; Bender, A.; Feuerstein, B.; Fritsch, P.O.; Romani, N.; et al. Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells. J. Exp. Med. 2002, 195, 1279–1288.
    • (2002) J. Exp. Med. , vol.195 , pp. 1279-1288
    • Schuler-Thurner, B.1    Schultz, E.S.2    Berger, T.G.3    Weinlich, G.4    Ebner, S.5    Woerl, P.6    Bender, A.7    Feuerstein, B.8    Fritsch, P.O.9    Romani, N.10
  • 52
    • 0034023485 scopus 로고    scopus 로고
    • Mature dendritic cells boost functionally superior CD8(+) t-cell in humans without foreign helper epitopes
    • Dhodapkar, M.V.; Krasovsky, J.; Steinman, R.M.; Bhardwaj, N. Mature dendritic cells boost functionally superior CD8(+) t-cell in humans without foreign helper epitopes. J. Clin. Investig. 2000, 105, 9–14.
    • (2000) J. Clin. Investig , vol.105 , pp. 9-14
    • Dhodapkar, M.V.1    Krasovsky, J.2    Steinman, R.M.3    Bhardwaj, N.4
  • 53
    • 0036378101 scopus 로고    scopus 로고
    • Immature, but not inactive: The tolerogenic function of immature dendritic cells
    • Mahnke, K.; Schmitt, E.; Bonifaz, L.; Enk, A.H.; Jonuleit, H. Immature, but not inactive: The tolerogenic function of immature dendritic cells. Immunol. Cell Biol. 2002, 80, 477–483.
    • (2002) Immunol. Cell Biol , vol.80 , pp. 477-483
    • Mahnke, K.1    Schmitt, E.2    Bonifaz, L.3    Enk, A.H.4    Jonuleit, H.5
  • 54
    • 77956122616 scopus 로고    scopus 로고
    • Dendritic cells in cancer immunotherapy
    • Schuler, G. Dendritic cells in cancer immunotherapy. Eur. J. Immunol. 2010, 40, 2123–2130.
    • (2010) Eur. J. Immunol , vol.40 , pp. 2123-2130
    • Schuler, G.1
  • 55
    • 0035869523 scopus 로고    scopus 로고
    • Dendritic cells injected via different routes induce immunity in cancer patients
    • Fong, L.; Brockstedt, D.; Benike, C.; Wu, L.; Engleman, E.G. Dendritic cells injected via different routes induce immunity in cancer patients. J. Immunol. 2001, 166, 4254–4259.
    • (2001) J. Immunol , vol.166 , pp. 4254-4259
    • Fong, L.1    Brockstedt, D.2    Benike, C.3    Wu, L.4    Engleman, E.G.5
  • 58
    • 84867765852 scopus 로고    scopus 로고
    • Phase I/II study of immunotherapy using tumor antigen-pulsed dendritic cells in patients with hepatocellular carcinoma
    • Tada, F.; Abe, M.; Hirooka, M.; Ikeda, Y.; Hiasa, Y.; Lee, Y.; Jung, N.C.; Lee, W.B.; Lee, H.S.; Bae, Y.S.; et al. Phase I/II study of immunotherapy using tumor antigen-pulsed dendritic cells in patients with hepatocellular carcinoma. Int. J. Oncol. 2012, 41, 1601–1609.
    • (2012) Int. J. Oncol. , vol.41 , pp. 1601-1609
    • Tada, F.1    Abe, M.2    Hirooka, M.3    Ikeda, Y.4    Hiasa, Y.5    Lee, Y.6    Jung, N.C.7    Lee, W.B.8    Lee, H.S.9    Bae, Y.S.10
  • 59
    • 84870985481 scopus 로고    scopus 로고
    • Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma: Results of the HGG-2006 phase I/II trial
    • Ardon, H.; Van Gool, S.W.; Verschuere, T.; Maes, W.; Fieuws, S.; Sciot, R.; Wilms, G.; Demaerel, P.; Goffin, J.; Van Calenbergh, F.; et al. Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma: Results of the HGG-2006 phase I/II trial. Cancer Immunol. Immunother. 2012, 61, 2033–2044.
    • (2012) Cancer Immunol. Immunother , vol.61 , pp. 2033-2044
    • Ardon, H.1    Van Gool, S.W.2    Verschuere, T.3    Maes, W.4    Fieuws, S.5    Sciot, R.6    Wilms, G.7    Demaerel, P.8    Goffin, J.9    Van Calenbergh, F.10
  • 60
    • 0032036433 scopus 로고    scopus 로고
    • Physical interaction between dendritic cells and tumor cells results in an immunogen that induces protective and therapeutic tumor rejection
    • Celluzzi, C.M.; Falo, L.D., Jr. Physical interaction between dendritic cells and tumor cells results in an immunogen that induces protective and therapeutic tumor rejection. J. Immunol. 1998, 160, 3081–3085.
    • (1998) J. Immunol , vol.160 , pp. 3081-3085
    • Celluzzi, C.M.1    Falo, L.D.2
  • 63
    • 84899116386 scopus 로고    scopus 로고
    • Autologous tumor lysate-pulsed dendritic cell immunotherapy with cytokine-induced killer cells improves survival in gastric and colorectal cancer patients
    • Gao, D.; Li, C.; Xie, X.; Zhao, P.; Wei, X.; Sun, W.; Liu, H.C.; Alexandrou, A.T.; Jones, J.; Zhao, R.; et al. Autologous tumor lysate-pulsed dendritic cell immunotherapy with cytokine-induced killer cells improves survival in gastric and colorectal cancer patients. PLoS ONE 2014, 9, e93886.
    • (2014) Plos ONE , vol.9
    • Gao, D.1    Li, C.2    Xie, X.3    Zhao, P.4    Wei, X.5    Sun, W.6    Liu, H.C.7    Alexandrou, A.T.8    Jones, J.9    Zhao, R.10
  • 66
    • 0034292406 scopus 로고    scopus 로고
    • Dendritic cells capture killed tumor cells and present their antigens to elicit tumor-specific immune responses
    • Nouri-Shirazi, M.; Banchereau, J.; Bell, D.; Burkeholder, S.; Kraus, E.T.; Davoust, J.; Palucka, K.A. Dendritic cells capture killed tumor cells and present their antigens to elicit tumor-specific immune responses. J. Immunol. 2000, 165, 3797–3803.
    • (2000) J. Immunol , vol.165 , pp. 3797-3803
    • Nouri-Shirazi, M.1    Banchereau, J.2    Bell, D.3    Burkeholder, S.4    Kraus, E.T.5    Davoust, J.6    Palucka, K.A.7
  • 70
    • 0036203164 scopus 로고    scopus 로고
    • Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-transfected dendritic cells
    • Nair, S.K.; Morse, M.; Boczkowski, D.; Cumming, R.I.; Vasovic, L.; Gilboa, E.; Lyerly, H.K. Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-transfected dendritic cells. Ann. Surg. 2002, 235, 540–549.
    • (2002) Ann. Surg , vol.235 , pp. 540-549
    • Nair, S.K.1    Morse, M.2    Boczkowski, D.3    Cumming, R.I.4    Vasovic, L.5    Gilboa, E.6    Lyerly, H.K.7
  • 71
    • 84890321725 scopus 로고    scopus 로고
    • CD8(+) T-cell priming and boosting: More antigen-presenting DC, or more antigen per DC?
    • Schaft, N.; Wellner, V.; Wohn, C.; Schuler, G.; Dorrie, J. CD8(+) T-cell priming and boosting: More antigen-presenting DC, or more antigen per DC? Cancer Immunol. Immunother. 2013, 62, 1769–1780.
    • (2013) Cancer Immunol. Immunother , vol.62 , pp. 1769-1780
    • Schaft, N.1    Wellner, V.2    Wohn, C.3    Schuler, G.4    Dorrie, J.5
  • 73
    • 84920265123 scopus 로고    scopus 로고
    • Induction of cytomegalovirus-specific T cell responses in healthy volunteers and allogeneic stem cell recipients using vaccination with messenger RNA-transfected dendritic cells
    • Van Craenenbroeck, A.H.; Smits, E.L.; Anguille, S.; Van de Velde, A.; Stein, B.; Braeckman, T.; Van Camp, K.; Nijs, G.; Ieven, M.; Goossens, H.; et al. Induction of cytomegalovirus-specific T cell responses in healthy volunteers and allogeneic stem cell recipients using vaccination with messenger RNA-transfected dendritic cells. Transplantation 2015, 99, 120–127.
    • (2015) Transplantation , vol.99 , pp. 120-127
    • Van Craenenbroeck, A.H.1    Smits, E.L.2    Anguille, S.3    Van De Velde, A.4    Stein, B.5    Braeckman, T.6    Van Camp, K.7    Nijs, G.8    Ieven, M.9    Goossens, H.10
  • 74
    • 79957986558 scopus 로고    scopus 로고
    • Adjuvant activity of the catalytic a1 domain of cholera toxin for retroviral antigens delivered by genegun
    • Bagley, K.C.; Lewis, G.K.; Fouts, T.R. Adjuvant activity of the catalytic a1 domain of cholera toxin for retroviral antigens delivered by genegun. Clin. Vaccine Immunol. 2011, 18, 922–930.
    • (2011) Clin. Vaccine Immunol , vol.18 , pp. 922-930
    • Bagley, K.C.1    Lewis, G.K.2    Fouts, T.R.3
  • 75
    • 0029820526 scopus 로고    scopus 로고
    • DNA-based immunization by in vivo transfection of dendritic cells
    • Condon, C.; Watkins, S.C.; Celluzzi, C.M.; Thompson, K.; Falo, L.D., Jr. DNA-based immunization by in vivo transfection of dendritic cells. Nat. Med. 1996, 2, 1122–1128.
    • (1996) Nat. Med , vol.2 , pp. 1122-1128
    • Condon, C.1    Watkins, S.C.2    Celluzzi, C.M.3    Thompson, K.4    Falo, L.D.5
  • 76
    • 0037086695 scopus 로고    scopus 로고
    • Simultaneous genegun immunisation with plasmids encoding antigen and GM-CSF: Significant enhancement of murine antivenom IgG1 titres
    • Harrison, R.A.; Richards, A.; Laing, G.D.; Theakston, R.D. Simultaneous genegun immunisation with plasmids encoding antigen and GM-CSF: Significant enhancement of murine antivenom IgG1 titres. Vaccine 2002, 20, 1702–1706.
    • (2002) Vaccine , vol.20 , pp. 1702-1706
    • Harrison, R.A.1    Richards, A.2    Laing, G.D.3    Theakston, R.D.4
  • 77
    • 0037047047 scopus 로고    scopus 로고
    • Human tumor-derived genomic DNA transduced into a recipient cell induces tumor-specific immune responses ex vivo
    • Whiteside, T.L.; Gambotto, A.; Albers, A.; Stanson, J.; Cohen, E.P. Human tumor-derived genomic DNA transduced into a recipient cell induces tumor-specific immune responses ex vivo. Proc. Nat. Acad. Sci. USA 2002, 99, 9415–9420.
    • (2002) Proc. Nat. Acad. Sci. USA , vol.99 , pp. 9415-9420
    • Whiteside, T.L.1    Gambotto, A.2    Albers, A.3    Stanson, J.4    Cohen, E.P.5
  • 79
    • 40049088465 scopus 로고    scopus 로고
    • Dendritic cells and epithelial cells: Linking innate and adaptive immunity in asthma
    • Hammad, H.; Lambrecht, B.N. Dendritic cells and epithelial cells: Linking innate and adaptive immunity in asthma. Nat. Rev. Immunol. 2008, 8, 193–204.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 193-204
    • Hammad, H.1    Lambrecht, B.N.2
  • 80
    • 84936112179 scopus 로고    scopus 로고
    • The role of active vaccination in cancer immunotherapy: Lessons from clinical trials
    • Kissick, H.T.; Sanda, M.G. The role of active vaccination in cancer immunotherapy: Lessons from clinical trials. Curr. Opin. Immunol. 2015, 35, 15–22.
    • (2015) Curr. Opin. Immunol , vol.35 , pp. 15-22
    • Kissick, H.T.1    Sanda, M.G.2
  • 81
    • 0034918104 scopus 로고    scopus 로고
    • Dendritic cells: On the move from bench to bedside
    • Nestle, F.O.; Banchereau, J.; Hart, D. Dendritic cells: On the move from bench to bedside. Nat. Med. 2001, 7, 761–765.
    • (2001) Nat. Med , vol.7 , pp. 761-765
    • Nestle, F.O.1    Banchereau, J.2    Hart, D.3
  • 82
    • 84928057119 scopus 로고    scopus 로고
    • Phase I pilot study of wilms tumor gene 1 peptide-pulsed dendritic cell vaccination combined with gemcitabine in pancreatic cancer
    • Mayanagi, S.; Kitago, M.; Sakurai, T.; Matsuda, T.; Fujita, T.; Higuchi, H.; Taguchi, J.; Takeuchi, H.; Itano, O.; Aiura, K.; et al. Phase I pilot study of wilms tumor gene 1 peptide-pulsed dendritic cell vaccination combined with gemcitabine in pancreatic cancer. Cancer Sci. 2015, 106, 397–406.
    • (2015) Cancer Sci , vol.106 , pp. 397-406
    • Mayanagi, S.1    Kitago, M.2    Sakurai, T.3    Matsuda, T.4    Fujita, T.5    Higuchi, H.6    Taguchi, J.7    Takeuchi, H.8    Itano, O.9    Aiura, K.10
  • 84
    • 84899731823 scopus 로고    scopus 로고
    • Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma
    • Chodon, T.; Comin-Anduix, B.; Chmielowski, B.; Koya, R.C.; Wu, Z.; Auerbach, M.; Ng, C.; Avramis, E.; Seja, E.; Villanueva, A.; et al. Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma. Clin. Cancer Res. 2014, 20, 2457–2465.
    • (2014) Clin. Cancer Res , vol.20 , pp. 2457-2465
    • Chodon, T.1    Comin-Anduix, B.2    Chmielowski, B.3    Koya, R.C.4    Wu, Z.5    Auerbach, M.6    Ng, C.7    Avramis, E.8    Seja, E.9    Villanueva, A.10
  • 88
    • 0033405438 scopus 로고    scopus 로고
    • Vaccination with MAGE-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma
    • Thurner, B.; Haendle, I.; Roder, C.; Dieckmann, D.; Keikavoussi, P.; Jonuleit, H.; Bender, A.; Maczek, C.; Schreiner, D.; von den Driesch, P.; et al. Vaccination with MAGE-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J. Exp. Med. 1999, 190, 1669–1678.
    • (1999) J. Exp. Med , vol.190 , pp. 1669-1678
    • Thurner, B.1    Haendle, I.2    Roder, C.3    Dieckmann, D.4    Keikavoussi, P.5    Jonuleit, H.6    Bender, A.7    Maczek, C.8    Schreiner, D.9    Von Den Driesch, P.10
  • 90
    • 54849437711 scopus 로고    scopus 로고
    • Review of clinical studies on dendritic cell-based vaccination of patients with malignant melanoma: Assessment of correlation between clinical response and vaccine parameters
    • Engell-Noerregaard, L.; Hansen, T.H.; Andersen, M.H.; Thor Straten, P.; Svane, I.M. Review of clinical studies on dendritic cell-based vaccination of patients with malignant melanoma: Assessment of correlation between clinical response and vaccine parameters. Cancer Immunol. Immunother. 2009, 58, 1–14.
    • (2009) Cancer Immunol. Immunother , vol.58 , pp. 1-14
    • Engell-Noerregaard, L.1    Hansen, T.H.2    Andersen, M.H.3    Thor Straten, P.4    Svane, I.M.5
  • 92
    • 70350532950 scopus 로고    scopus 로고
    • Clinical considerations in developing dendritic cell vaccine based immunotherapy protocols in cancer
    • Murthy, V.; Moiyadi, A.; Sawant, R.; Sarin, R. Clinical considerations in developing dendritic cell vaccine based immunotherapy protocols in cancer. Curr. Mol. Med. 2009, 9, 725–731.
    • (2009) Curr. Mol. Med , vol.9 , pp. 725-731
    • Murthy, V.1    Moiyadi, A.2    Sawant, R.3    Sarin, R.4
  • 94
    • 84938350452 scopus 로고    scopus 로고
    • Combination cancer immunotherapy and new immunomodulatory targets
    • Mahoney, K.M.; Rennert, P.D.; Freeman, G.J. Combination cancer immunotherapy and new immunomodulatory targets. Nat. Rev. Drug Discov. 2015, 14, 561–584.
    • (2015) Nat. Rev. Drug Discov , vol.14 , pp. 561-584
    • Mahoney, K.M.1    Rennert, P.D.2    Freeman, G.J.3
  • 95
    • 84926629603 scopus 로고    scopus 로고
    • Dendritic cell-based vaccine efficacy: Aiming for hot spots
    • Pizzurro, G.A.; Barrio, M.M. Dendritic cell-based vaccine efficacy: Aiming for hot spots. Front. Immunol. 2015.
    • (2015) Front. Immunol
    • Pizzurro, G.A.1    Barrio, M.M.2
  • 98
    • 84951828193 scopus 로고    scopus 로고
    • Randomized, placebo-controlled, phase III trial of yeast-derived granulocyte-macrophage colony-stimulating factor (GM-CSF) versus peptide vaccination versus GM-CSF plus peptide vaccination versus placebo in patients with no evidence of disease after complete surgical resection of locally advanced and/or stage IV melanoma: A trial of the eastern cooperative oncology group-american college of radiology imaging network cancer research group (e4697)
    • Lawson, D.H.; Lee, S.; Zhao, F.; Tarhini, A.A.; Margolin, K.A.; Ernstoff, M.S.; Atkins, M.B.; Cohen, G.I.; Whiteside, T.L.; Butterfield, L.H.; et al. Randomized, placebo-controlled, phase III trial of yeast-derived granulocyte-macrophage colony-stimulating factor (GM-CSF) versus peptide vaccination versus GM-CSF plus peptide vaccination versus placebo in patients with no evidence of disease after complete surgical resection of locally advanced and/or stage IV melanoma: A trial of the eastern cooperative oncology group-american college of radiology imaging network cancer research group (e4697). J. Clin. Oncol. 2015, 33, 4066–4076.
    • (2015) J. Clin. Oncol. , vol.33 , pp. 4066-4076
    • Lawson, D.H.1    Lee, S.2    Zhao, F.3    Tarhini, A.A.4    Margolin, K.A.5    Ernstoff, M.S.6    Atkins, M.B.7    Cohen, G.I.8    Whiteside, T.L.9    Butterfield, L.H.10
  • 99
    • 84860347746 scopus 로고    scopus 로고
    • Phase II study of personalized peptide vaccination for castration-resistant prostate cancer patients who failed in docetaxel-based chemotherapy
    • Noguchi, M.; Moriya, F.; Suekane, S.; Matsuoka, K.; Arai, G.; Matsueda, S.; Sasada, T.; Yamada, A.; Itoh, K. Phase II study of personalized peptide vaccination for castration-resistant prostate cancer patients who failed in docetaxel-based chemotherapy. Prostate 2012, 72, 834–845.
    • (2012) Prostate , vol.72 , pp. 834-845
    • Noguchi, M.1    Moriya, F.2    Suekane, S.3    Matsuoka, K.4    Arai, G.5    Matsueda, S.6    Sasada, T.7    Yamada, A.8    Itoh, K.9
  • 106
    • 84908308856 scopus 로고    scopus 로고
    • Effective induction of anti-tumor immunity using p5 HER-2/neu derived peptide encapsulated in fusogenic DOTAP cationic liposomes co-administrated with CpG-ODN
    • Mansourian, M.; Badiee, A.; Jalali, S.A.; Shariat, S.; Yazdani, M.; Amin, M.; Jaafari, M.R. Effective induction of anti-tumor immunity using p5 HER-2/neu derived peptide encapsulated in fusogenic DOTAP cationic liposomes co-administrated with CpG-ODN. Immunol. Lett. 2014, 162, 87–93.
    • (2014) Immunol. Lett , vol.162 , pp. 87-93
    • Mansourian, M.1    Badiee, A.2    Jalali, S.A.3    Shariat, S.4    Yazdani, M.5    Amin, M.6    Jaafari, M.R.7
  • 107
    • 84925467063 scopus 로고    scopus 로고
    • Cationic liposomes loaded with a synthetic long peptide and poly(I: C): A defined adjuvanted vaccine for induction of antigen-specific T cell cytotoxicity
    • Varypataki, E.M.; van der Maaden, K.; Bouwstra, J.; Ossendorp, F.; Jiskoot, W. Cationic liposomes loaded with a synthetic long peptide and poly(i: C): A defined adjuvanted vaccine for induction of antigen-specific T cell cytotoxicity. AAPS J. 2015, 17, 216–226.
    • (2015) AAPS J , vol.17 , pp. 216-226
    • Varypataki, E.M.1    Van Der Maaden, K.2    Bouwstra, J.3    Ossendorp, F.4    Jiskoot, W.5
  • 108
    • 80053479472 scopus 로고    scopus 로고
    • Inspire: A phase III study of the BLP25 liposome vaccine (l-BLP25) in asian patients with unresectable stage III non-small cell lung cancer
    • Wu, Y.L.; Park, K.; Soo, R.A.; Sun, Y.; Tyroller, K.; Wages, D.; Ely, G.; Yang, J.C.; Mok, T. Inspire: A phase III study of the BLP25 liposome vaccine (l-BLP25) in asian patients with unresectable stage III non-small cell lung cancer. BMC Cancer 2011.
    • (2011) BMC Cancer
    • Wu, Y.L.1    Park, K.2    Soo, R.A.3    Sun, Y.4    Tyroller, K.5    Wages, D.6    Ely, G.7    Yang, J.C.8    Mok, T.9
  • 109
    • 7444242049 scopus 로고    scopus 로고
    • Vax: An autologous, hapten-modified vaccine for human cancer
    • Berd, D. M-vax: An autologous, hapten-modified vaccine for human cancer. Expert Rev. Vaccines 2004, 3, 521–527.
    • (2004) Expert Rev. Vaccines , vol.3 , pp. 521-527
    • Berd, D.M.1
  • 111
    • 0037089687 scopus 로고    scopus 로고
    • Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: Overall results of a randomized trial of the southwest oncology group
    • Sondak, V.K.; Liu, P.Y.; Tuthill, R.J.; Kempf, R.A.; Unger, J.M.; Sosman, J.A.; Thompson, J.A.; Weiss, G.R.; Redman, B.G.; Jakowatz, J.G.; et al. Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: Overall results of a randomized trial of the southwest oncology group. J. Clin. Oncol. 2002, 20, 2058–2066.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 2058-2066
    • Sondak, V.K.1    Liu, P.Y.2    Tuthill, R.J.3    Kempf, R.A.4    Unger, J.M.5    Sosman, J.A.6    Thompson, J.A.7    Weiss, G.R.8    Redman, B.G.9    Jakowatz, J.G.10
  • 112
    • 34548035780 scopus 로고    scopus 로고
    • Design and development of synthetic peptide vaccines: Past, present and future. Expert
    • Bijker, M.S.; Melief, C.J.; Offringa, R.; van der Burg, S.H. Design and development of synthetic peptide vaccines: Past, present and future. Expert Rev. Vaccines 2007, 6, 591–603.
    • (2007) Rev. Vaccines , vol.6 , pp. 591-603
    • Bijker, M.S.1    Melief, C.J.2    Offringa, R.3    Van Der Burg, S.H.4
  • 114
    • 77958482764 scopus 로고    scopus 로고
    • Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytes
    • Kamphorst, A.O.; Guermonprez, P.; Dudziak, D.; Nussenzweig, M.C. Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytes. J. Immunol. 2010, 185, 3426–3435.
    • (2010) J. Immunol , vol.185 , pp. 3426-3435
    • Kamphorst, A.O.1    Guermonprez, P.2    Dudziak, D.3    Nussenzweig, M.C.4
  • 116
    • 84879208415 scopus 로고    scopus 로고
    • Dendritic cell-based nanovaccines for cancer immunotherapy
    • Paulis, L.E.; Mandal, S.; Kreutz, M.; Figdor, C.G. Dendritic cell-based nanovaccines for cancer immunotherapy. Curr. Opin. Immunol. 2013, 25, 389–395.
    • (2013) Curr. Opin. Immunol , vol.25 , pp. 389-395
    • Paulis, L.E.1    Mandal, S.2    Kreutz, M.3    Figdor, C.G.4
  • 117
    • 33750728433 scopus 로고    scopus 로고
    • Targeting dendritic cells with biomaterials: Developing the next generation of vaccines
    • Reddy, S.T.; Swartz, M.A.; Hubbell, J.A. Targeting dendritic cells with biomaterials: Developing the next generation of vaccines. Trends Immunol. 2006, 27, 573–579.
    • (2006) Trends Immunol , vol.27 , pp. 573-579
    • Reddy, S.T.1    Swartz, M.A.2    Hubbell, J.A.3
  • 118
    • 84863480395 scopus 로고    scopus 로고
    • Molecular engineering of antibodies for therapeutic and diagnostic purposes
    • Ducancel, F.; Muller, B.H. Molecular engineering of antibodies for therapeutic and diagnostic purposes. MAbs 2012, 4, 445–457.
    • (2012) Mabs , vol.4 , pp. 445-457
    • Ducancel, F.1    Muller, B.H.2
  • 119
    • 84907887830 scopus 로고    scopus 로고
    • Principles and engineering of antibody folding and assembly. Biochim. Biophys
    • Feige, M.J.; Buchner, J. Principles and engineering of antibody folding and assembly. Biochim. Biophys. Acta 2014, 1844, 2024–2031.
    • (2014) Acta , vol.1844 , pp. 2024-2031
    • Feige, M.J.1    Buchner, J.2
  • 121
    • 80051885494 scopus 로고    scopus 로고
    • Inhibitory fcgamma receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies
    • Li, F.; Ravetch, J.V. Inhibitory fcgamma receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies. Science 2011, 333, 1030–1034.
    • (2011) Science , vol.333 , pp. 1030-1034
    • Li, F.1    Ravetch, J.V.2
  • 122
    • 80053578013 scopus 로고    scopus 로고
    • Impact of differential glycosylation on IgG activity
    • Lux, A.; Nimmerjahn, F. Impact of differential glycosylation on IgG activity. Adv. Exp. Med. Biol. 2011, 780, 113–124.
    • (2011) Adv. Exp. Med. Biol , vol.780 , pp. 113-124
    • Lux, A.1    Nimmerjahn, F.2
  • 123
    • 84862245287 scopus 로고    scopus 로고
    • Translating basic mechanisms of IgG effector activity into next generation cancer therapies
    • Nimmerjahn, F.; Ravetch, J.V. Translating basic mechanisms of IgG effector activity into next generation cancer therapies. Cancer Immun. 2012, 12, 13.
    • (2012) Cancer Immun , vol.12 , pp. 13
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 124
    • 34548229364 scopus 로고    scopus 로고
    • Fcrn: The neonatal fc receptor comes of age
    • Roopenian, D.C.; Akilesh, S. Fcrn: The neonatal fc receptor comes of age. Nat. Rev. Immunol. 2007, 7, 715–725.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 715-725
    • Roopenian, D.C.1    Akilesh, S.2
  • 125
    • 84939254457 scopus 로고    scopus 로고
    • Targeting fcrn for the modulation of antibody dynamics
    • Ward, E.S.; Devanaboyina, S.C.; Ober, R.J. Targeting fcrn for the modulation of antibody dynamics. Mol. Immunol. 2015, 67, 131–141.
    • (2015) Mol. Immunol , vol.67 , pp. 131-141
    • Ward, E.S.1    Devanaboyina, S.C.2    Ober, R.J.3
  • 126
    • 84876404526 scopus 로고    scopus 로고
    • Induction of protective immunity against mycobacterium tuberculosis by delivery of esx antigens into airway dendritic cells
    • Dong, H.; Stanek, O.; Salvador, F.R.; Langer, U.; Morillon, E.; Ung, C.; Sebo, P.; Leclerc, C.; Majlessi, L. Induction of protective immunity against mycobacterium tuberculosis by delivery of esx antigens into airway dendritic cells. Mucosal Immunol. 2013, 6, 522–534.
    • (2013) Mucosal Immunol , vol.6 , pp. 522-534
    • Dong, H.1    Stanek, O.2    Salvador, F.R.3    Langer, U.4    Morillon, E.5    Ung, C.6    Sebo, P.7    Leclerc, C.8    Majlessi, L.9
  • 127
    • 77349095894 scopus 로고    scopus 로고
    • Origin and functional heterogeneity of non-lymphoid tissue dendritic cells in mice
    • Helft, J.; Ginhoux, F.; Bogunovic, M.; Merad, M. Origin and functional heterogeneity of non-lymphoid tissue dendritic cells in mice. Immunol. Rev. 2010, 234, 55–75.
    • (2010) Immunol. Rev , vol.234 , pp. 55-75
    • Helft, J.1    Ginhoux, F.2    Bogunovic, M.3    Merad, M.4
  • 128
    • 54549096767 scopus 로고    scopus 로고
    • CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease
    • Hadeiba, H.; Sato, T.; Habtezion, A.; Oderup, C.; Pan, J.; Butcher, E.C. CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease. Nat. Immunol. 2008, 9, 1253–1260.
    • (2008) Nat. Immunol , vol.9 , pp. 1253-1260
    • Hadeiba, H.1    Sato, T.2    Habtezion, A.3    Oderup, C.4    Pan, J.5    Butcher, E.C.6
  • 130
    • 0142166682 scopus 로고    scopus 로고
    • Origin, precursors and differentiation of mouse dendritic cells
    • Ardavin, C. Origin, precursors and differentiation of mouse dendritic cells. Nat. Rev. Immunol. 2003, 3, 582–590.
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 582-590
    • Ardavin, C.1
  • 131
    • 0032773794 scopus 로고    scopus 로고
    • Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon
    • Cella, M.; Jarrossay, D.; Facchetti, F.; Alebardi, O.; Nakajima, H.; Lanzavecchia, A.; Colonna, M. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nat. Med. 1999, 5, 919–923.
    • (1999) Nat. Med , vol.5 , pp. 919-923
    • Cella, M.1    Jarrossay, D.2    Facchetti, F.3    Alebardi, O.4    Nakajima, H.5    Lanzavecchia, A.6    Colonna, M.7
  • 132
    • 48749085127 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: Sensing nucleic acids in viral infection and autoimmune diseases
    • Gilliet, M.; Cao, W.; Liu, Y.J. Plasmacytoid dendritic cells: Sensing nucleic acids in viral infection and autoimmune diseases. Nat. Rev. Immunol. 2008, 8, 594–606.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 594-606
    • Gilliet, M.1    Cao, W.2    Liu, Y.J.3
  • 134
    • 77950490375 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of toll-like receptor 7 agonists
    • Rajagopal, D.; Paturel, C.; Morel, Y.; Uematsu, S.; Akira, S.; Diebold, S.S. Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of toll-like receptor 7 agonists. Blood 2010, 115, 1949–1957.
    • (2010) Blood , vol.115 , pp. 1949-1957
    • Rajagopal, D.1    Paturel, C.2    Morel, Y.3    Uematsu, S.4    Akira, S.5    Diebold, S.S.6
  • 135
    • 68149167760 scopus 로고    scopus 로고
    • Cutting edge: B220+CCR9αdendritic cells are not plasmacytoid dendritic cells but are precursors of conventional dendritic cells
    • Segura, E.; Wong, J.; Villadangos, J.A. Cutting edge: B220+CCR9α dendritic cells are not plasmacytoid dendritic cells but are precursors of conventional dendritic cells. J. Immunol. 2009, 183, 1514–1517.
    • (2009) J. Immunol , vol.183 , pp. 1514-1517
    • Segura, E.1    Wong, J.2    Villadangos, J.A.3
  • 139
    • 73349104434 scopus 로고    scopus 로고
    • Dominant expression of the inhibitory fcgammariib prevents antigen presentation by murine plasmacytoid dendritic cells
    • Flores, M.; Desai, D.D.; Downie, M.; Liang, B.; Reilly, M.P.; McKenzie, S.E.; Clynes, R. Dominant expression of the inhibitory fcgammariib prevents antigen presentation by murine plasmacytoid dendritic cells. J. Immunol. 2009, 183, 7129–7139.
    • (2009) J. Immunol , vol.183 , pp. 7129-7139
    • Flores, M.1    Desai, D.D.2    Downie, M.3    Liang, B.4    Reilly, M.P.5    McKenzie, S.E.6    Clynes, R.7
  • 141
    • 83755173163 scopus 로고    scopus 로고
    • Antigen targeting to plasmacytoid dendritic cells via Siglec-H inhibits Th cell-dependent autoimmunity
    • Loschko, J.; Heink, S.; Hackl, D.; Dudziak, D.; Reindl, W.; Korn, T.; Krug, A.B. Antigen targeting to plasmacytoid dendritic cells via Siglec-H inhibits Th cell-dependent autoimmunity. J. Immunol. 2011, 187, 6346–6356.
    • (2011) J. Immunol , vol.187 , pp. 6346-6356
    • Loschko, J.1    Heink, S.2    Hackl, D.3    Dudziak, D.4    Reindl, W.5    Korn, T.6    Krug, A.B.7
  • 143
    • 43249130188 scopus 로고    scopus 로고
    • Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production
    • Meyer-Wentrup, F.; Benitez-Ribas, D.; Tacken, P.J.; Punt, C.J.; Figdor, C.G.; de Vries, I.J.; Adema, G.J. Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production. Blood 2008, 111, 4245–4253.
    • (2008) Blood , vol.111 , pp. 4245-4253
    • Meyer-Wentrup, F.1    Benitez-Ribas, D.2    Tacken, P.J.3    Punt, C.J.4    Figdor, C.G.5    De Vries, I.J.6    Adema, G.J.7
  • 144
    • 55749092126 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation
    • Mouries, J.; Moron, G.; Schlecht, G.; Escriou, N.; Dadaglio, G.; Leclerc, C. Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation. Blood 2008, 112, 3713–3722.
    • (2008) Blood , vol.112 , pp. 3713-3722
    • Mouries, J.1    Moron, G.2    Schlecht, G.3    Escriou, N.4    Dadaglio, G.5    Leclerc, C.6
  • 145
    • 79953059788 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: Recent progress and open questions
    • Reizis, B.; Bunin, A.; Ghosh, H.S.; Lewis, K.L.; Sisirak, V. Plasmacytoid dendritic cells: Recent progress and open questions. Ann. Rev. Immunol. 2011, 29, 163–183.
    • (2011) Ann. Rev. Immunol , vol.29 , pp. 163-183
    • Reizis, B.1    Bunin, A.2    Ghosh, H.S.3    Lewis, K.L.4    Sisirak, V.5
  • 146
    • 34250893815 scopus 로고    scopus 로고
    • Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo
    • Villadangos, J.A.; Schnorrer, P. Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo. Nat. Rev. Immunol. 2007, 7, 543–555.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 543-555
    • Villadangos, J.A.1    Schnorrer, P.2
  • 147
    • 84926631436 scopus 로고    scopus 로고
    • Mouse conventional dendritic cells can be universally classified based on the mutually exclusive expression of XCR1 and sirpalpha
    • Gurka, S.; Hartung, E.; Becker, M.; Kroczek, R.A. Mouse conventional dendritic cells can be universally classified based on the mutually exclusive expression of XCR1 and sirpalpha. Front. Immunol. 2015.
    • (2015) Front. Immunol
    • Gurka, S.1    Hartung, E.2    Becker, M.3    Kroczek, R.A.4
  • 149
    • 84901368457 scopus 로고    scopus 로고
    • The origins and functions of dendritic cells and macrophages in the skin
    • Malissen, B.; Tamoutounour, S.; Henri, S. The origins and functions of dendritic cells and macrophages in the skin. Nat. Rev. Immunol. 2014, 14, 417–428.
    • (2014) Nat. Rev. Immunol , vol.14 , pp. 417-428
    • Malissen, B.1    Tamoutounour, S.2    Henri, S.3
  • 150
    • 84856826706 scopus 로고    scopus 로고
    • CD64 expression distinguishes monocyte-derived and conventional dendritic cells and reveals their distinct role during intramuscular immunization
    • Langlet, C.; Tamoutounour, S.; Henri, S.; Luche, H.; Ardouin, L.; Gregoire, C.; Malissen, B.; Guilliams, M. CD64 expression distinguishes monocyte-derived and conventional dendritic cells and reveals their distinct role during intramuscular immunization. J. Immunol. 2012, 188, 1751–1760.
    • (2012) J. Immunol , vol.188 , pp. 1751-1760
    • Langlet, C.1    Tamoutounour, S.2    Henri, S.3    Luche, H.4    Ardouin, L.5    Gregoire, C.6    Malissen, B.7    Guilliams, M.8
  • 151
    • 84926659434 scopus 로고    scopus 로고
    • The known unknowns of the human dendritic cell network
    • Durand, M.; Segura, E. The known unknowns of the human dendritic cell network. Front. Immunol. 2015.
    • (2015) Front. Immunol
    • Durand, M.1    Segura, E.2
  • 154
    • 84880721353 scopus 로고    scopus 로고
    • Dendritic-cell-based therapeutic cancer vaccines
    • Palucka, K.; Banchereau, J. Dendritic-cell-based therapeutic cancer vaccines. Immunity 2013, 39, 38–48.
    • (2013) Immunity , vol.39 , pp. 38-48
    • Palucka, K.1    Banchereau, J.2
  • 155
    • 84935119898 scopus 로고    scopus 로고
    • Human and mouse mononuclear phagocyte networks: A tale of two species?
    • Reynolds, G.; Haniffa, M. Human and mouse mononuclear phagocyte networks: A tale of two species? Front. Immunol. 2015.
    • (2015) Front. Immunol
    • Reynolds, G.1    Haniffa, M.2
  • 161
    • 0029009977 scopus 로고
    • The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
    • Jiang, W.; Swiggard, W.J.; Heufler, C.; Peng, M.; Mirza, A.; Steinman, R.M.; Nussenzweig, M.C. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 1995, 375, 151–155.
    • (1995) Nature , vol.375 , pp. 151-155
    • Jiang, W.1    Swiggard, W.J.2    Heufler, C.3    Peng, M.4    Mirza, A.5    Steinman, R.M.6    Nussenzweig, M.C.7
  • 162
    • 0029051182 scopus 로고
    • Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. I. Expression on dendritic cells and other subsets of mouse leukocytes
    • Inaba, K.; Swiggard, W.J.; Inaba, M.; Meltzer, J.; Mirza, A.; Sasagawa, T.; Nussenzweig, M.C.; Steinman, R.M. Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. I. Expression on dendritic cells and other subsets of mouse leukocytes. Cell. Immunol. 1995, 163, 148–156.
    • (1995) Cell. Immunol. , vol.163 , pp. 148-156
    • Inaba, K.1    Swiggard, W.J.2    Inaba, M.3    Meltzer, J.4    Mirza, A.5    Sasagawa, T.6    Nussenzweig, M.C.7    Steinman, R.M.8
  • 163
    • 0022511898 scopus 로고
    • Langerhans’ cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody
    • Kraal, G.; Breel, M.; Janse, M.; Bruin, G. Langerhans’ cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody. J. Exp. Med. 1986, 163, 981–997.
    • (1986) J. Exp. Med , vol.163 , pp. 981-997
    • Kraal, G.1    Breel, M.2    Janse, M.3    Bruin, G.4
  • 164
    • 0029062409 scopus 로고
    • Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. II. Expression in situ in lymphoid and nonlymphoid tissues
    • Witmer-Pack, M.D.; Swiggard, W.J.; Mirza, A.; Inaba, K.; Steinman, R.M. Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. II. Expression in situ in lymphoid and nonlymphoid tissues. Cell. Immunol. 1995, 163, 157–162.
    • (1995) Cell. Immunol , vol.163 , pp. 157-162
    • Witmer-Pack, M.D.1    Swiggard, W.J.2    Mirza, A.3    Inaba, K.4    Steinman, R.M.5
  • 165
    • 0038792101 scopus 로고    scopus 로고
    • Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells
    • Mahnke, K.; Qian, Y.; Knop, J.; Enk, A.H. Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells. Blood 2003, 101, 4862–4869.
    • (2003) Blood , vol.101 , pp. 4862-4869
    • Mahnke, K.1    Qian, Y.2    Knop, J.3    Enk, A.H.4
  • 168
  • 169
    • 57649137960 scopus 로고    scopus 로고
    • Plasminogen activator Pla of Yersinia pestis utilizes murine DEC-205 (CD205) as a receptor to promote dissemination
    • Zhang, S.S.; Park, C.G.; Zhang, P.; Bartra, S.S.; Plano, G.V.; Klena, J.D.; Skurnik, M.; Hinnebusch, B.J.; Chen, T. Plasminogen activator Pla of Yersinia pestis utilizes murine DEC-205 (CD205) as a receptor to promote dissemination. J. Biol. Chem. 2008, 283, 31511–31521.
    • (2008) J. Biol. Chem , vol.283 , pp. 31511-31521
    • Zhang, S.S.1    Park, C.G.2    Zhang, P.3    Bartra, S.S.4    Plano, G.V.5    Klena, J.D.6    Skurnik, M.7    Hinnebusch, B.J.8    Chen, T.9
  • 170
    • 77955012706 scopus 로고    scopus 로고
    • Efficient generation of a monoclonal antibody against the human C-type lectin receptor DCIR by targeting murine dendritic cells
    • Heidkamp, G.F.; Neubert, K.; Haertel, E.; Nimmerjahn, F.; Nussenzweig, M.C.; Dudziak, D. Efficient generation of a monoclonal antibody against the human C-type lectin receptor DCIR by targeting murine dendritic cells. Immunol. Lett. 2010, 132, 69–78.
    • (2010) Immunol. Lett , vol.132 , pp. 69-78
    • Heidkamp, G.F.1    Neubert, K.2    Haertel, E.3    Nimmerjahn, F.4    Nussenzweig, M.C.5    Dudziak, D.6
  • 176
    • 84899860613 scopus 로고    scopus 로고
    • DC-SIGN plays a stronger role than DCIR in mediating HIV-1 capture and transfer
    • Jin, W.; Li, C.; Du, T.; Hu, K.; Huang, X.; Hu, Q. DC-SIGN plays a stronger role than DCIR in mediating HIV-1 capture and transfer. Virology 2014.
    • (2014) Virology
    • Jin, W.1    Li, C.2    Du, T.3    Hu, K.4    Huang, X.5    Hu, Q.6
  • 177
    • 51649113484 scopus 로고    scopus 로고
    • The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans-and cis-infection pathways
    • Lambert, A.A.; Gilbert, C.; Richard, M.; Beaulieu, A.D.; Tremblay, M.J. The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans-and cis-infection pathways. Blood 2008, 112, 1299–1307.
    • (2008) Blood , vol.112 , pp. 1299-1307
    • Lambert, A.A.1    Gilbert, C.2    Richard, M.3    Beaulieu, A.D.4    Tremblay, M.J.5
  • 178
    • 44049103003 scopus 로고    scopus 로고
    • Cutting edge: Langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo
    • Idoyaga, J.; Cheong, C.; Suda, K.; Suda, N.; Kim, J.Y.; Lee, H.; Park, C.G.; Steinman, R.M. Cutting edge: Langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo. J. Immunol. 2008, 180, 3647–3650.
    • (2008) J. Immunol , vol.180 , pp. 3647-3650
    • Idoyaga, J.1    Cheong, C.2    Suda, K.3    Suda, N.4    Kim, J.Y.5    Lee, H.6    Park, C.G.7    Steinman, R.M.8
  • 181
    • 84904246019 scopus 로고    scopus 로고
    • Targeted delivery of α -galactosylceramide to CD8 α + dendritic cells optimizes type I NKT cell-based antitumor responses
    • Macho-Fernandez, E.; Cruz, L.J.; Ghinnagow, R.; Fontaine, J.; Bialecki, E.; Frisch, B.; Trottein, F.; Faveeuw, C. Targeted delivery of α -galactosylceramide to CD8 α + dendritic cells optimizes type I NKT cell-based antitumor responses. J. Immunol. 2014, 193, 961–969.
    • (2014) J. Immunol , vol.193 , pp. 961-969
    • Macho-Fernandez, E.1    Cruz, L.J.2    Ghinnagow, R.3    Fontaine, J.4    Bialecki, E.5    Frisch, B.6    Trottein, F.7    Faveeuw, C.8
  • 182
    • 77957131592 scopus 로고    scopus 로고
    • Targeting of LCRV virulence protein from yersinia pestis to dendritic cells protects mice against pneumonic plague
    • Do, Y.; Koh, H.; Park, C.G.; Dudziak, D.; Seo, P.; Mehandru, S.; Choi, J.H.; Cheong, C.; Park, S.; Perlin, D.S.; et al. Targeting of LCRV virulence protein from yersinia pestis to dendritic cells protects mice against pneumonic plague. Eur. J. Immunol. 2010, 40, 2791–2796.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 2791-2796
    • Do, Y.1    Koh, H.2    Park, C.G.3    Dudziak, D.4    Seo, P.5    Mehandru, S.6    Choi, J.H.7    Cheong, C.8    Park, S.9    Perlin, D.S.10
  • 185
    • 67650445798 scopus 로고    scopus 로고
    • Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
    • Longhi, M.P.; Trumpfheller, C.; Idoyaga, J.; Caskey, M.; Matos, I.; Kluger, C.; Salazar, A.M.; Colonna, M.; Steinman, R.M. Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant. J. Exp. Med. 2009, 206, 1589–1602.
    • (2009) J. Exp. Med , vol.206 , pp. 1589-1602
    • Longhi, M.P.1    Trumpfheller, C.2    Idoyaga, J.3    Caskey, M.4    Matos, I.5    Kluger, C.6    Salazar, A.M.7    Colonna, M.8    Steinman, R.M.9
  • 186
    • 84961155452 scopus 로고    scopus 로고
    • Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses
    • Ruane, D.; Chorny, A.; Lee, H.; Faith, J.; Pandey, G.; Shan, M.; Simchoni, N.; Rahman, A.; Garg, A.; Weinstein, E.G.; et al. Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses. J. Exp. Med. 2016, 213, 53–73.
    • (2016) J. Exp. Med. , vol.213 , pp. 53-73
    • Ruane, D.1    Chorny, A.2    Lee, H.3    Faith, J.4    Pandey, G.5    Shan, M.6    Simchoni, N.7    Rahman, A.8    Garg, A.9    Weinstein, E.G.10
  • 188
    • 84879478989 scopus 로고    scopus 로고
    • Targeting antigens to dendritic cells in vivo induces protective immunity
    • Matos, I.; Mizenina, O.; Lubkin, A.; Steinman, R.M.; Idoyaga, J. Targeting antigens to dendritic cells in vivo induces protective immunity. PLoS ONE 2013, 8, e67453.
    • (2013) Plos ONE , vol.8
    • Matos, I.1    Mizenina, O.2    Lubkin, A.3    Steinman, R.M.4    Idoyaga, J.5
  • 189
    • 84862777557 scopus 로고    scopus 로고
    • Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice
    • Wang, B.; Zaidi, N.; He, L.Z.; Zhang, L.; Kuroiwa, J.M.; Keler, T.; Steinman, R.M. Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice. Breast Cancer Res. 2012.
    • (2012) Breast Cancer Res
    • Wang, B.1    Zaidi, N.2    He, L.Z.3    Zhang, L.4    Kuroiwa, J.M.5    Keler, T.6    Steinman, R.M.7
  • 190
    • 84923013834 scopus 로고    scopus 로고
    • Antigen targeting to dendritic cells allows the identification of a CD4 T-cell epitope within an immunodominant trypanosoma cruzi antigen
    • Rampazo, E.V.; Amorim, K.N.; Yamamoto, M.M.; Panatieri, R.H.; Rodrigues, M.M.; Boscardin, S.B. Antigen targeting to dendritic cells allows the identification of a CD4 T-cell epitope within an immunodominant trypanosoma cruzi antigen. PLoS ONE 2015, 10, e0117778.
    • (2015) Plos ONE , vol.10
    • Rampazo, E.V.1    Amorim, K.N.2    Yamamoto, M.M.3    Panatieri, R.H.4    Rodrigues, M.M.5    Boscardin, S.B.6
  • 192
    • 79952116856 scopus 로고    scopus 로고
    • Kretschmer, K. Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice
    • Petzold, C.; Riewaldt, J.; Koenig, T.; Schallenberg, S.; Kretschmer, K. Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice. Rev Diabet. Stud. 2010, 7, 47–61.
    • (2010) Rev Diabet. Stud , vol.7 , pp. 47-61
    • Petzold, C.1    Riewaldt, J.2    Koenig, T.3    Schallenberg, S.4
  • 193
    • 33845425072 scopus 로고    scopus 로고
    • Dendritic cell targeting of surviving protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin
    • Charalambous, A.; Oks, M.; Nchinda, G.; Yamazaki, S.; Steinman, R.M. Dendritic cell targeting of surviving protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin. J. Immunol. 2006, 177, 8410–8421.
    • (2006) J. Immunol , vol.177 , pp. 8410-8421
    • Charalambous, A.1    Oks, M.2    Nchinda, G.3    Yamazaki, S.4    Steinman, R.M.5
  • 194
    • 84886440668 scopus 로고    scopus 로고
    • DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8(+) T cells independently of PD-1 and PD-L1
    • Mukherjee, G.; Geliebter, A.; Babad, J.; Santamaria, P.; Serreze, D.V.; Freeman, G.J.; Tarbell, K.V.; Sharpe, A.; DiLorenzo, T.P. DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8(+) T cells independently of PD-1 and PD-L1. Int. Immunol. 2013, 25, 651–660.
    • (2013) Int. Immunol , vol.25 , pp. 651-660
    • Mukherjee, G.1    Geliebter, A.2    Babad, J.3    Santamaria, P.4    Serreze, D.V.5    Freeman, G.J.6    Tarbell, K.V.7    Sharpe, A.8    Dilorenzo, T.P.9
  • 197
    • 84884216197 scopus 로고    scopus 로고
    • Targeting of autoantigens to DEC205(+) dendritic cells in vivo suppresses experimental allergic encephalomyelitis in mice
    • Ring, S.; Maas, M.; Nettelbeck, D.M.; Enk, A.H.; Mahnke, K. Targeting of autoantigens to DEC205(+) dendritic cells in vivo suppresses experimental allergic encephalomyelitis in mice. J. Immunol. 2013, 191, 2938–2947.
    • (2013) J. Immunol , vol.191 , pp. 2938-2947
    • Ring, S.1    Maas, M.2    Nettelbeck, D.M.3    Enk, A.H.4    Mahnke, K.5
  • 199
    • 3042523520 scopus 로고    scopus 로고
    • Targeting dendritic cells with antigen-containing liposomes: A highly effective procedure for induction of antitumor immunity and for tumor immunotherapy
    • van Broekhoven, C.L.; Parish, C.R.; Demangel, C.; Britton, W.J.; Altin, J.G. Targeting dendritic cells with antigen-containing liposomes: A highly effective procedure for induction of antitumor immunity and for tumor immunotherapy. Cancer Res. 2004, 64, 4357–4365.
    • (2004) Cancer Res , vol.64 , pp. 4357-4365
    • Van Broekhoven, C.L.1    Parish, C.R.2    Demangel, C.3    Britton, W.J.4    Altin, J.G.5
  • 200
    • 0037122011 scopus 로고    scopus 로고
    • Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance
    • Bonifaz, L.; Bonnyay, D.; Mahnke, K.; Rivera, M.; Nussenzweig, M.C.; Steinman, R.M. Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J. Exp. Med. 2002, 196, 1627–1638.
    • (2002) J. Exp. Med. , vol.196 , pp. 1627-1638
    • Bonifaz, L.1    Bonnyay, D.2    Mahnke, K.3    Rivera, M.4    Nussenzweig, M.C.5    Steinman, R.M.6
  • 201
    • 84857487963 scopus 로고    scopus 로고
    • Skin langerin+ dendritic cells transport intradermally injected anti-DEC-205 antibodies but are not essential for subsequent cytotoxic CD8+ T cell responses
    • Flacher, V.; Tripp, C.H.; Haid, B.; Kissenpfennig, A.; Malissen, B.; Stoitzner, P.; Idoyaga, J.; Romani, N. Skin langerin+ dendritic cells transport intradermally injected anti-DEC-205 antibodies but are not essential for subsequent cytotoxic CD8+ T cell responses. J. Immunol. 2012, 188, 2146–2155.
    • (2012) J. Immunol , vol.188 , pp. 2146-2155
    • Flacher, V.1    Tripp, C.H.2    Haid, B.3    Kissenpfennig, A.4    Malissen, B.5    Stoitzner, P.6    Idoyaga, J.7    Romani, N.8
  • 204
    • 51649112493 scopus 로고    scopus 로고
    • Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses
    • Gurer, C.; Strowig, T.; Brilot, F.; Pack, M.; Trumpfheller, C.; Arrey, F.; Park, C.G.; Steinman, R.M.; Munz, C. Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. Blood 2008, 112, 1231–1239.
    • (2008) Blood , vol.112 , pp. 1231-1239
    • Gurer, C.1    Strowig, T.2    Brilot, F.3    Pack, M.4    Trumpfheller, C.5    Arrey, F.6    Park, C.G.7    Steinman, R.M.8    Munz, C.9
  • 207
  • 210
    • 77951737543 scopus 로고    scopus 로고
    • Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A
    • Joffre, O.P.; Sancho, D.; Zelenay, S.; Keller, A.M.; Reis e Sousa, C. Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A. Eur. J. Immunol. 2010, 40, 1255–1265.
    • (2010) Eur. J. Immunol , vol.40 , pp. 1255-1265
    • Joffre, O.P.1    Sancho, D.2    Zelenay, S.3    Keller, A.M.4    Reis E Sousa, C.5
  • 212
    • 79960544931 scopus 로고    scopus 로고
    • Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype
    • Lahoud, M.H.; Ahmet, F.; Kitsoulis, S.; Wan, S.S.; Vremec, D.; Lee, C.N.; Phipson, B.; Shi, W.; Smyth, G.K.; Lew, A.M.; et al. Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype. J. Immunol. 2011, 187, 842–850.
    • (2011) J. Immunol , vol.187 , pp. 842-850
    • Lahoud, M.H.1    Ahmet, F.2    Kitsoulis, S.3    Wan, S.S.4    Vremec, D.5    Lee, C.N.6    Phipson, B.7    Shi, W.8    Smyth, G.K.9    Lew, A.M.10
  • 214
    • 67649184779 scopus 로고    scopus 로고
    • The C-type lectin clec12a present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses
    • Lahoud, M.H.; Proietto, A.I.; Ahmet, F.; Kitsoulis, S.; Eidsmo, L.; Wu, L.; Sathe, P.; Pietersz, S.; Chang, H.W.; Walker, I.D.; et al. The C-type lectin clec12a present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses. J. Immunol. 2009, 182, 7587–7594.
    • (2009) J. Immunol , vol.182 , pp. 7587-7594
    • Lahoud, M.H.1    Proietto, A.I.2    Ahmet, F.3    Kitsoulis, S.4    Eidsmo, L.5    Wu, L.6    Sathe, P.7    Pietersz, S.8    Chang, H.W.9    Walker, I.D.10
  • 215
    • 33746864909 scopus 로고    scopus 로고
    • Preferential induction of CD4+ T cell responses through in vivo targeting of antigen to dendritic cell-associated C-type lectin-1
    • Carter, R.W.; Thompson, C.; Reid, D.M.; Wong, S.Y.; Tough, D.F. Preferential induction of CD4+ T cell responses through in vivo targeting of antigen to dendritic cell-associated C-type lectin-1. J. Immunol. 2006, 177, 2276–2284.
    • (2006) J. Immunol , vol.177 , pp. 2276-2284
    • Carter, R.W.1    Thompson, C.2    Reid, D.M.3    Wong, S.Y.4    Tough, D.F.5
  • 216
    • 84902130691 scopus 로고    scopus 로고
    • Induction and activation of human Th17 by targeting antigens to dendritic cells via Dectin-1
    • Duluc, D.; Joo, H.; Ni, L.; Yin, W.; Upchurch, K.; Li, D.; Xue, Y.; Klucar, P.; Zurawski, S.; Zurawski, G.; et al. Induction and activation of human Th17 by targeting antigens to dendritic cells via Dectin-1. J. Immunol. 2014, 192, 5776–5788.
    • (2014) J. Immunol , vol.192 , pp. 5776-5788
    • Duluc, D.1    Joo, H.2    Ni, L.3    Yin, W.4    Upchurch, K.5    Li, D.6    Xue, Y.7    Klucar, P.8    Zurawski, S.9    Zurawski, G.10
  • 217
    • 78649902080 scopus 로고    scopus 로고
    • Concomitant activation and antigen uptake via human Dectin-1 results in potent antigen-specific CD8+ T cell responses
    • Ni, L.; Gayet, I.; Zurawski, S.; Duluc, D.; Flamar, A.L.; Li, X.H.; O’Bar, A.; Clayton, S.; Palucka, A.K.; Zurawski, G.; et al. Concomitant activation and antigen uptake via human Dectin-1 results in potent antigen-specific CD8+ T cell responses. J. Immunol. 2010, 185, 3504–3513.
    • (2010) J. Immunol , vol.185 , pp. 3504-3513
    • Ni, L.1    Gayet, I.2    Zurawski, S.3    Duluc, D.4    Flamar, A.L.5    Li, X.H.6    O’Bar, A.7    Clayton, S.8    Palucka, A.K.9    Zurawski, G.10
  • 218
    • 84918531042 scopus 로고    scopus 로고
    • Murine langerin+ dermal dendritic cells prime CD8+ T cells while langerhans cells induce cross-tolerance. EMBO Mol
    • Flacher, V.; Tripp, C.H.; Mairhofer, D.G.; Steinman, R.M.; Stoitzner, P.; Idoyaga, J.; Romani, N. Murine langerin+ dermal dendritic cells prime CD8+ T cells while langerhans cells induce cross-tolerance. EMBO Mol. Med. 2014, 6, 1191–1204.
    • (2014) Med , vol.6 , pp. 1191-1204
    • Flacher, V.1    Tripp, C.H.2    Mairhofer, D.G.3    Steinman, R.M.4    Stoitzner, P.5    Idoyaga, J.6    Romani, N.7
  • 219
    • 23744481998 scopus 로고    scopus 로고
    • Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody
    • Tacken, P.J.; de Vries, I.J.; Gijzen, K.; Joosten, B.; Wu, D.; Rother, R.P.; Faas, S.J.; Punt, C.J.; Torensma, R.; Adema, G.J.; et al. Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody. Blood 2005, 106, 1278–1285.
    • (2005) Blood , vol.106 , pp. 1278-1285
    • Tacken, P.J.1    De Vries, I.J.2    Gijzen, K.3    Joosten, B.4    Wu, D.5    Rother, R.P.6    Faas, S.J.7    Punt, C.J.8    Torensma, R.9    Adema, G.J.10
  • 221
    • 80054117550 scopus 로고    scopus 로고
    • Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation
    • Tacken, P.J.; Ginter, W.; Berod, L.; Cruz, L.J.; Joosten, B.; Sparwasser, T.; Figdor, C.G.; Cambi, A. Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation. Blood 2011, 118, 4111–4119.
    • (2011) Blood , vol.118 , pp. 4111-4119
    • Tacken, P.J.1    Ginter, W.2    Berod, L.3    Cruz, L.J.4    Joosten, B.5    Sparwasser, T.6    Figdor, C.G.7    Cambi, A.8
  • 223
    • 34748840807 scopus 로고    scopus 로고
    • In vivo targeting of antigens to human dendritic cells through DC-SIGN elicits stimulatory immune responses and inhibits tumor growth in grafted mouse models
    • Kretz-Rommel, A.; Qin, F.; Dakappagari, N.; Torensma, R.; Faas, S.; Wu, D.; Bowdish, K.S. In vivo targeting of antigens to human dendritic cells through DC-SIGN elicits stimulatory immune responses and inhibits tumor growth in grafted mouse models. J. Immunother. 2007, 30, 715–726.
    • (2007) J. Immunother , vol.30 , pp. 715-726
    • Kretz-Rommel, A.1    Qin, F.2    Dakappagari, N.3    Torensma, R.4    Faas, S.5    Wu, D.6    Bowdish, K.S.7
  • 225
    • 10744226740 scopus 로고    scopus 로고
    • Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma T cell responses via multiple HLA molecules
    • Ramakrishna, V.; Treml, J.F.; Vitale, L.; Connolly, J.E.; O’Neill, T.; Smith, P.A.; Jones, C.L.; He, L.Z.; Goldstein, J.; Wallace, P.K.; et al. Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma T cell responses via multiple HLA molecules. J. Immunol. 2004, 172, 2845–2852.
    • (2004) J. Immunol , vol.172 , pp. 2845-2852
    • Ramakrishna, V.1    Treml, J.F.2    Vitale, L.3    Connolly, J.E.4    O’Neill, T.5    Smith, P.A.6    Jones, C.L.7    He, L.Z.8    Goldstein, J.9    Wallace, P.K.10
  • 226
    • 33846987932 scopus 로고    scopus 로고
    • Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells
    • Ramakrishna, V.; Vasilakos, J.P.; Tario, J.D., Jr.; Berger, M.A.; Wallace, P.K.; Keler, T. Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells. J. Transl. Med. 2007.
    • (2007) J. Transl. Med
    • Ramakrishna, V.1    Vasilakos, J.P.2    Tario, J.D.3    Berger, M.A.4    Wallace, P.K.5    Keler, T.6
  • 227
  • 228
    • 68049111686 scopus 로고    scopus 로고
    • Targeted delivery of tumor antigens to activated dendritic cells via CD11c molecules induces potent antitumor immunity in mice
    • Wei, H.; Wang, S.; Zhang, D.; Hou, S.; Qian, W.; Li, B.; Guo, H.; Kou, G.; He, J.; Wang, H.; et al. Targeted delivery of tumor antigens to activated dendritic cells via CD11c molecules induces potent antitumor immunity in mice. Clin. Cancer Res. 2009, 15, 4612–4621.
    • (2009) Clin. Cancer Res , vol.15 , pp. 4612-4621
    • Wei, H.1    Wang, S.2    Zhang, D.3    Hou, S.4    Qian, W.5    Li, B.6    Guo, H.7    Kou, G.8    He, J.9    Wang, H.10
  • 234
    • 33644755502 scopus 로고    scopus 로고
    • Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors
    • Zhang, J.; Raper, A.; Sugita, N.; Hingorani, R.; Salio, M.; Palmowski, M.J.; Cerundolo, V.; Crocker, P.R. Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors. Blood 2006, 107, 3600–3608.
    • (2006) Blood , vol.107 , pp. 3600-3608
    • Zhang, J.1    Raper, A.2    Sugita, N.3    Hingorani, R.4    Salio, M.5    Palmowski, M.J.6    Cerundolo, V.7    Crocker, P.R.8
  • 235
    • 34547809370 scopus 로고    scopus 로고
    • Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cells
    • Sapoznikov, A.; Fischer, J.A.; Zaft, T.; Krauthgamer, R.; Dzionek, A.; Jung, S. Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cells. J. Exp. Med. 2007, 204, 1923–1933.
    • (2007) J. Exp. Med , vol.204 , pp. 1923-1933
    • Sapoznikov, A.1    Fischer, J.A.2    Zaft, T.3    Krauthgamer, R.4    Dzionek, A.5    Jung, S.6
  • 236
    • 84935100535 scopus 로고    scopus 로고
    • The role of dendritic cell subsets and innate immunity in the pathogenesis of type 1 diabetes and other autoimmune diseases
    • Price, J.D.; Tarbell, K.V. The role of dendritic cell subsets and innate immunity in the pathogenesis of type 1 diabetes and other autoimmune diseases. Front. Immunol. 2015.
    • (2015) Front. Immunol
    • Price, J.D.1    Tarbell, K.V.2
  • 239
    • 33745728738 scopus 로고    scopus 로고
    • Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: A role for capturing hepatitis C virus particles
    • Lai, W.K.; Sun, P.J.; Zhang, J.; Jennings, A.; Lalor, P.F.; Hubscher, S.; McKeating, J.A.; Adams, D.H. Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: A role for capturing hepatitis C virus particles. Am. J. Pathol. 2006, 169, 200–208.
    • (2006) Am. J. Pathol. , vol.169 , pp. 200-208
    • Lai, W.K.1    Sun, P.J.2    Zhang, J.3    Jennings, A.4    Lalor, P.F.5    Hubscher, S.6    McKeating, J.A.7    Adams, D.H.8
  • 241
    • 84884812281 scopus 로고    scopus 로고
    • The physiological role of DC-SIGN: A tale of mice and men
    • Garcia-Vallejo, J.J.; van Kooyk, Y. The physiological role of DC-SIGN: A tale of mice and men. Trends Immunol. 2013, 34, 482–486.
    • (2013) Trends Immunol , vol.34 , pp. 482-486
    • Garcia-Vallejo, J.J.1    Van Kooyk, Y.2
  • 243
    • 33745988599 scopus 로고    scopus 로고
    • Widely divergent biochemical properties of the complete set of mouse DC-SIGN-related proteins
    • Powlesland, A.S.; Ward, E.M.; Sadhu, S.K.; Guo, Y.; Taylor, M.E.; Drickamer, K. Widely divergent biochemical properties of the complete set of mouse DC-SIGN-related proteins. J. Biol. Chem. 2006, 281, 20440–20449.
    • (2006) J. Biol. Chem. , vol.281 , pp. 20440-20449
    • Powlesland, A.S.1    Ward, E.M.2    Sadhu, S.K.3    Guo, Y.4    Taylor, M.E.5    Drickamer, K.6
  • 246
    • 77953522371 scopus 로고    scopus 로고
    • Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells
    • Bachem, A.; Guttler, S.; Hartung, E.; Ebstein, F.; Schaefer, M.; Tannert, A.; Salama, A.; Movassaghi, K.; Opitz, C.; Mages, H.W.; et al. Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells. J. Exp. Med. 2010, 207, 1273–1281.
    • (2010) J. Exp. Med. , vol.207 , pp. 1273-1281
    • Bachem, A.1    Guttler, S.2    Hartung, E.3    Ebstein, F.4    Schaefer, M.5    Tannert, A.6    Salama, A.7    Movassaghi, K.8    Opitz, C.9    Mages, H.W.10
  • 247
    • 77349086110 scopus 로고    scopus 로고
    • Comparative genomics as a tool to reveal functional equivalences between human and mouse dendritic cell subsets
    • Crozat, K.; Guiton, R.; Guilliams, M.; Henri, S.; Baranek, T.; Schwartz-Cornil, I.; Malissen, B.; Dalod, M. Comparative genomics as a tool to reveal functional equivalences between human and mouse dendritic cell subsets. Immunol. Rev. 2010, 234, 177–198.
    • (2010) Immunol. Rev , vol.234 , pp. 177-198
    • Crozat, K.1    Guiton, R.2    Guilliams, M.3    Henri, S.4    Baranek, T.5    Schwartz-Cornil, I.6    Malissen, B.7    Dalod, M.8
  • 249
    • 84899109357 scopus 로고    scopus 로고
    • Human blood dendritic cell subsets exhibit discriminative pattern recognition receptor profiles
    • Lundberg, K.; Rydnert, F.; Greiff, L.; Lindstedt, M. Human blood dendritic cell subsets exhibit discriminative pattern recognition receptor profiles. Immunology 2014, 142, 279–288.
    • (2014) Immunology , vol.142 , pp. 279-288
    • Lundberg, K.1    Rydnert, F.2    Greiff, L.3    Lindstedt, M.4
  • 251
    • 84890987173 scopus 로고    scopus 로고
    • Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice
    • Watchmaker, P.B.; Lahl, K.; Lee, M.; Baumjohann, D.; Morton, J.; Kim, S.J.; Zeng, R.; Dent, A.; Ansel, K.M.; Diamond, B.; et al. Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice. Nat. Immunol. 2014, 15, 98–108.
    • (2014) Nat. Immunol , vol.15 , pp. 98-108
    • Watchmaker, P.B.1    Lahl, K.2    Lee, M.3    Baumjohann, D.4    Morton, J.5    Kim, S.J.6    Zeng, R.7    Dent, A.8    Ansel, K.M.9    Diamond, B.10
  • 252
    • 84866178367 scopus 로고    scopus 로고
    • Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells
    • Chatterjee, B.; Smed-Sorensen, A.; Cohn, L.; Chalouni, C.; Vandlen, R.; Lee, B.C.; Widger, J.; Keler, T.; Delamarre, L.; Mellman, I. Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells. Blood 2012, 120, 2011–2020.
    • (2012) Blood , vol.120 , pp. 2011-2020
    • Chatterjee, B.1    Smed-Sorensen, A.2    Cohn, L.3    Chalouni, C.4    Vandlen, R.5    Lee, B.C.6    Widger, J.7    Keler, T.8    Delamarre, L.9    Mellman, I.10
  • 254
    • 84884776453 scopus 로고    scopus 로고
    • Signalling C-type lectins in antimicrobial immunity
    • Drummond, R.A.; Brown, G.D. Signalling C-type lectins in antimicrobial immunity. PLoS Pathog. 2013, 9.
    • (2013) Plos Pathog , pp. 9
    • Drummond, R.A.1    Brown, G.D.2
  • 256
    • 18844412640 scopus 로고    scopus 로고
    • The human beta-glucan receptor is widely expressed and functionally equivalent to murine Dectin-1 on primary cells
    • Willment, J.A.; Marshall, A.S.; Reid, D.M.; Williams, D.L.; Wong, S.Y.; Gordon, S.; Brown, G.D. The human beta-glucan receptor is widely expressed and functionally equivalent to murine Dectin-1 on primary cells. Eur. J. Immunol. 2005, 35, 1539–1547.
    • (2005) Eur. J. Immunol , vol.35 , pp. 1539-1547
    • Willment, J.A.1    Marshall, A.S.2    Reid, D.M.3    Williams, D.L.4    Wong, S.Y.5    Gordon, S.6    Brown, G.D.7
  • 257
    • 56549104117 scopus 로고    scopus 로고
    • CARD9 signaling in the innate immune response
    • Ruland, J. CARD9 signaling in the innate immune response. Ann. N. Y. Acad. Sci. 2008, 1143, 35–44.
    • (2008) Ann. N. Y. Acad. Sci , vol.1143 , pp. 35-44
    • Ruland, J.1
  • 259
    • 3042818861 scopus 로고    scopus 로고
    • Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions
    • Reid, D.M.; Montoya, M.; Taylor, P.R.; Borrow, P.; Gordon, S.; Brown, G.D.; Wong, S.Y. Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions. J. Leukoc. Biol. 2004, 76, 86–94.
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 86-94
    • Reid, D.M.1    Montoya, M.2    Taylor, P.R.3    Borrow, P.4    Gordon, S.5    Brown, G.D.6    Wong, S.Y.7
  • 260
    • 77349112874 scopus 로고    scopus 로고
    • Langerhans cells and more: Langerin-expressing dendritic cell subsets in the skin
    • Romani, N.; Clausen, B.E.; Stoitzner, P. Langerhans cells and more: Langerin-expressing dendritic cell subsets in the skin. Immunol. Rev. 2010, 234, 120–141.
    • (2010) Immunol. Rev , vol.234 , pp. 120-141
    • Romani, N.1    Clausen, B.E.2    Stoitzner, P.3
  • 263
    • 0034681178 scopus 로고    scopus 로고
    • Rapid antibody responses by low-dose, single-step, dendritic cell-targeted immunization
    • Wang, H.; Griffiths, M.N.; Burton, D.R.; Ghazal, P. Rapid antibody responses by low-dose, single-step, dendritic cell-targeted immunization. Proc. Nat. Acad. Sci. USA 2000, 97, 847–852.
    • (2000) Proc. Nat. Acad. Sci. USA , vol.97 , pp. 847-852
    • Wang, H.1    Griffiths, M.N.2    Burton, D.R.3    Ghazal, P.4
  • 265
    • 33747803946 scopus 로고    scopus 로고
    • Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation
    • Blasius, A.L.; Giurisato, E.; Cella, M.; Schreiber, R.D.; Shaw, A.S.; Colonna, M. Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation. J. Immunol. 2006, 177, 3260–3265.
    • (2006) J. Immunol , vol.177 , pp. 3260-3265
    • Blasius, A.L.1    Giurisato, E.2    Cella, M.3    Schreiber, R.D.4    Shaw, A.S.5    Colonna, M.6
  • 266
    • 84945273111 scopus 로고    scopus 로고
    • Enhanced humoral responses induced by targeting of antigen to murine dendritic cells. Scand
    • Pugholm, L.H.; Petersen, L.R.; Sondergaard, E.K.; Varming, K.; Agger, R. Enhanced humoral responses induced by targeting of antigen to murine dendritic cells. Scand. J. Immunol. 2015, 82, 515–522.
    • (2015) J. Immunol , vol.82 , pp. 515-522
    • Pugholm, L.H.1    Petersen, L.R.2    Sondergaard, E.K.3    Varming, K.4    Agger, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.