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Volumn 987, Issue , 2003, Pages 15-25

Dendritic cell function in Vivo during the steady state: A role in peripheral tolerance

Author keywords

Antigen presentation; DEC 205; Dendritic cells; Endocytosis; Peripheral tolerance

Indexed keywords

ANTIGEN PRESENTATION; AUTOIMMUNITY; CELL DEATH; CELL FUNCTION; CELL MATURATION; CELLULAR IMMUNITY; CONFERENCE PAPER; GENE SILENCING; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; IN VIVO STUDY; INFECTION; INFLAMMATION; MOLECULAR RECOGNITION; NONHUMAN; PHAGOCYTOSIS; REGULATORY MECHANISM; STEADY STATE; SUPPRESSOR CELL; T LYMPHOCYTE; THYMUS;

EID: 0037565445     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2003.tb06029.x     Document Type: Conference Paper
Times cited : (399)

References (66)
  • 1
    • 0024571804 scopus 로고
    • Does T-cell tolerance require a dedicated antigen-presenting cell?
    • MATZINGER, P. & S. GUERDER. 1989. Does T-cell tolerance require a dedicated antigen-presenting cell? Nature 338: 74-76.
    • (1989) Nature , vol.338 , pp. 74-76
    • Matzinger, P.1    Guerder, S.2
  • 2
    • 0027940262 scopus 로고
    • Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen
    • ZAL, T., A. VOLKMANN & B. STOCKINGER. 1994. Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen. J. Exp. Med. 180: 2089-2099.
    • (1994) J. Exp. Med. , vol.180 , pp. 2089-2099
    • Zal, T.1    Volkmann, A.2    Stockinger, B.3
  • 3
    • 0031568068 scopus 로고    scopus 로고
    • Antigen-presenting cells in thymus that can negatively select MHC class II-restricted T cells recognizing a circulating self antigen
    • VOLKMANN, A., T. ZAL & B. STOCKINGER. 1997. Antigen-presenting cells in thymus that can negatively select MHC class II-restricted T cells recognizing a circulating self antigen. J. Immunol. 158: 693-706.
    • (1997) J. Immunol. , vol.158 , pp. 693-706
    • Volkmann, A.1    Zal, T.2    Stockinger, B.3
  • 4
    • 0034507693 scopus 로고    scopus 로고
    • Impact of negative selection on the T cell repertoire reactive to a self-peptide: A large fraction of T cell clones escapes clonal detection
    • BOUNEAUD, C., P. KOURILSKY & P. BOUSSO. 2000. Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal detection. Immunity 13: 829-840.
    • (2000) Immunity , vol.13 , pp. 829-840
    • Bouneaud, C.1    Kourilsky, P.2    Bousso, P.3
  • 5
    • 0035899359 scopus 로고    scopus 로고
    • A purgative mastery
    • NOSSAL, G.J.V. 2001. A purgative mastery. Nature 412: 685-686.
    • (2001) Nature , vol.412 , pp. 685-686
    • Nossal, G.J.V.1
  • 6
    • 0028466130 scopus 로고
    • Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
    • KEARNEY, E.R., K.A. PAPE, D.Y. LOH, et al. 1994. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1: 327-339.
    • (1994) Immunity , vol.1 , pp. 327-339
    • Kearney, E.R.1    Pape, K.A.2    Loh, D.Y.3
  • 7
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and fas in T cell apoptosis and peripheral tolerance
    • PARIJS, L.V., A. IBRAGHIMOV & A.K. ABBAS. 1996. The roles of costimulation and fas in T cell apoptosis and peripheral tolerance. Immunity 4: 321-328.
    • (1996) Immunity , vol.4 , pp. 321-328
    • Parijs, L.V.1    Ibraghimov, A.2    Abbas, A.K.3
  • 8
    • 0029006188 scopus 로고
    • T cell priming versus T cell tolerance induced by synthetic peptides
    • AICHELE, P., K. BRDUSCHA-RIEM, R.M. ZINKERNAGEL, et al. 1995. T cell priming versus T cell tolerance induced by synthetic peptides. J. Exp. Med. 182: 261-266.
    • (1995) J. Exp. Med. , vol.182 , pp. 261-266
    • Aichele, P.1    Brduscha-Riem, K.2    Zinkernagel, R.M.3
  • 9
    • 0030745938 scopus 로고    scopus 로고
    • Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody
    • DADAGLIO, G., C.A. NELSON, M.B. DECK, et al. 1997. Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody. Immunity 6: 727-738.
    • (1997) Immunity , vol.6 , pp. 727-738
    • Dadaglio, G.1    Nelson, C.A.2    Deck, M.B.3
  • 10
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
    • STEINMAN, R.M. & M.C. NUSSENZWEIG. 2002. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc. Natl. Acad. Sci. USA 99: 351-358.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 351-358
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 11
    • 0028360611 scopus 로고
    • Origin and steady-state turnover of class II MHC-bearing dendritic cells in the epithelium of the conducting airways
    • HOLT, P.G., S. HAINING, D.J. NELSON, et al. 1994. Origin and steady-state turnover of class II MHC-bearing dendritic cells in the epithelium of the conducting airways. J. Immunol. 153: 256-261.
    • (1994) J. Immunol. , vol.153 , pp. 256-261
    • Holt, P.G.1    Haining, S.2    Nelson, D.J.3
  • 12
    • 0034672034 scopus 로고    scopus 로고
    • The development, maturation, and turnover rate of mouse spleen dendritic cell populations
    • KAMATH, A.T., J. POOLEY, M.A. O'KEEFFE, et al. 2000. The development, maturation, and turnover rate of mouse spleen dendritic cell populations. J. Immunol. 165: 6762-6770.
    • (2000) J. Immunol. , vol.165 , pp. 6762-6770
    • Kamath, A.T.1    Pooley, J.2    O'Keeffe, M.A.3
  • 13
    • 0022491032 scopus 로고
    • The immunologic properties of purified Langerhans cells: Distinct requirements for the stimulation of unprimed and sensitized T lymphocytes
    • INABA, K., G. SCHULER, M.D. WITMER, et al. 1986. The immunologic properties of purified Langerhans cells: distinct requirements for the stimulation of unprimed and sensitized T lymphocytes. J. Exp. Med. 164: 605-613.
    • (1986) J. Exp. Med. , vol.164 , pp. 605-613
    • Inaba, K.1    Schuler, G.2    Witmer, M.D.3
  • 14
    • 0024549594 scopus 로고
    • Presentation of exogenous protein antigens by dendritic cells to T cell clones: Intact protein is presented best by immature, epidermal Langerhans cells
    • ROMANI, N., S. KOIDE, M. CROWLEY, et al. 1989. Presentation of exogenous protein antigens by dendritic cells to T cell clones: intact protein is presented best by immature, epidermal Langerhans cells. J. Exp. Med. 169: 1169-1178.
    • (1989) J. Exp. Med. , vol.169 , pp. 1169-1178
    • Romani, N.1    Koide, S.2    Crowley, M.3
  • 15
    • 0024600415 scopus 로고
    • A small number of anti-CD3 molecules on dendritic cells stimulate DNA synthesis in mouse T lymphocytes
    • ROMANI, N., K. INABA, E. PURE, et al. 1989. A small number of anti-CD3 molecules on dendritic cells stimulate DNA synthesis in mouse T lymphocytes. J. Exp. Med. 169: 1153-1168.
    • (1989) J. Exp. Med. , vol.169 , pp. 1153-1168
    • Romani, N.1    Inaba, K.2    Pure, E.3
  • 16
    • 0032754286 scopus 로고    scopus 로고
    • Rapid generation of broad T-cell immunity in humans after single injection of mature dendritic cells
    • DHODAPKAR, M., R.M. STEINMAN, M. SAPP, et al. 1999. Rapid generation of broad T-cell immunity in humans after single injection of mature dendritic cells. J. Clin. Invest. 104: 173-180.
    • (1999) J. Clin. Invest. , vol.104 , pp. 173-180
    • Dhodapkar, M.1    Steinman, R.M.2    Sapp, M.3
  • 17
    • 0034023485 scopus 로고    scopus 로고
    • Mature dendritic cells boost functionally superior T cells in humans without foreign helper epitopes
    • DHODAPKAR, M.V., J. KRASOVSKY, R.M. STEINMAN, et al. 2000. Mature dendritic cells boost functionally superior T cells in humans without foreign helper epitopes. J. Clin. Invest. 105: R9-R14.
    • (2000) J. Clin. Invest. , vol.105
    • Dhodapkar, M.V.1    Krasovsky, J.2    Steinman, R.M.3
  • 18
    • 0034665304 scopus 로고    scopus 로고
    • Mage-3 and influenza-matrix peptide-specific cytotoxic T cells are inducible in terminal stage HLA-A2.1+ melanoma patients by mature monocyte-derived dendritic cells
    • SCHULER-THURNER, B., D. DIECKMANN, P. KEIKAVOUSSI, et al. 2000. Mage-3 and influenza-matrix peptide-specific cytotoxic T cells are inducible in terminal stage HLA-A2.1+ melanoma patients by mature monocyte-derived dendritic cells. J. Immunol. 165: 3492-3496.
    • (2000) J. Immunol. , vol.165 , pp. 3492-3496
    • Schuler-Thurner, B.1    Dieckmann, D.2    Keikavoussi, P.3
  • 19
    • 0035417932 scopus 로고    scopus 로고
    • Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine
    • BANCHEREAU, J., A.K. PALUCKA, M. DHODAPKAR, et al. 2001. Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine. Cancer Res. 61: 6451-6458.
    • (2001) Cancer Res. , vol.61 , pp. 6451-6458
    • Banchereau, J.1    Palucka, A.K.2    Dhodapkar, M.3
  • 21
    • 0034695889 scopus 로고    scopus 로고
    • Salmonella-induced apoptosis of infected macrophages results in presentation of a bacteria-encoded antigen after uptake by bystander dendritic cells
    • YRLID, U. & M.J. WICK. 2000. Salmonella-induced apoptosis of infected macrophages results in presentation of a bacteria-encoded antigen after uptake by bystander dendritic cells. J. Exp. Med. 191: 613-623.
    • (2000) J. Exp. Med. , vol.191 , pp. 613-623
    • Yrlid, U.1    Wick, M.J.2
  • 22
    • 0035177431 scopus 로고    scopus 로고
    • Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes
    • VERMAELEN, K.Y., I. CARRO-MUINO, B.N. LAMBRECHT, et al. 2001. Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. J. Exp. Med. 193: 51-60.
    • (2001) J. Exp. Med. , vol.193 , pp. 51-60
    • Vermaelen, K.Y.1    Carro-Muino, I.2    Lambrecht, B.N.3
  • 23
    • 0027218703 scopus 로고
    • Small amounts of superantigen, when presented on dendritic cells, are sufficient to initiate T cell responses
    • BHARDWAJ, N., J.W. YOUNG, A.J. NISANIAN, et al. 1993. Small amounts of superantigen, when presented on dendritic cells, are sufficient to initiate T cell responses. J. Exp. Med. 178: 633-642.
    • (1993) J. Exp. Med. , vol.178 , pp. 633-642
    • Bhardwaj, N.1    Young, J.W.2    Nisanian, A.J.3
  • 24
    • 0034614886 scopus 로고    scopus 로고
    • The induction of tolerance by dendritic cells that have captured apoptotic cells
    • STEINMAN, R.M., S. TURLEY, I. MELLMAN, et al. 2000. The induction of tolerance by dendritic cells that have captured apoptotic cells. J. Exp. Med. 191: 411-416.
    • (2000) J. Exp. Med. , vol.191 , pp. 411-416
    • Steinman, R.M.1    Turley, S.2    Mellman, I.3
  • 25
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • HAWIGER, D., K. INABA, Y. DORSETT, et al. 2001. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J. Exp. Med. 194: 769-780.
    • (2001) J. Exp. Med. , vol.194 , pp. 769-780
    • Hawiger, D.1    Inaba, K.2    Dorsett, Y.3
  • 27
    • 0037152164 scopus 로고    scopus 로고
    • Immune tolerance after delivery of dying cells to dendritic cells in situ
    • LIU, K., T. IYODA, M. SATERNUS, et al. 2002. Immune tolerance after delivery of dying cells to dendritic cells in situ. J. Exp. Med. 196: 1091-1097.
    • (2002) J. Exp. Med. , vol.196 , pp. 1091-1097
    • Liu, K.1    Iyoda, T.2    Saternus, M.3
  • 28
    • 0036659913 scopus 로고    scopus 로고
    • + regulatory T cells in vivo in humans
    • + regulatory T cells in vivo in humans. Blood 100: 174-177.
    • (2002) Blood , vol.100 , pp. 174-177
    • Dhodapkar, M.V.1    Steinman, R.M.2
  • 29
    • 0037033427 scopus 로고    scopus 로고
    • Repetitive injections of dendritic cells matured with tumor necrosis factor α induce antigen-specific protection of mice from autoimmunity
    • MENGES, M., S. ROSSNER, C. VOIGTLANDER, et al. 2002. Repetitive injections of dendritic cells matured with tumor necrosis factor α induce antigen-specific protection of mice from autoimmunity. J. Exp. Med. 195: 15-22.
    • (2002) J. Exp. Med. , vol.195 , pp. 15-22
    • Menges, M.1    Rossner, S.2    Voigtlander, C.3
  • 30
    • 0022578348 scopus 로고
    • Intrathymic presentation of circulating non-MHC antigens by medullary dendritic cells. An antigen-dependent microenviroment for T cell differentiation
    • KYEWSKI, B.A., C.G. FATHMAN & R.V. ROUSE. 1986. Intrathymic presentation of circulating non-MHC antigens by medullary dendritic cells. An antigen-dependent microenviroment for T cell differentiation. J. Exp. Med. 163: 231-246.
    • (1986) J. Exp. Med. , vol.163 , pp. 231-246
    • Kyewski, B.A.1    Fathman, C.G.2    Rouse, R.V.3
  • 31
    • 0023865277 scopus 로고
    • MHC class II antigen-bearing dendritic cells in pulmonary tissues of the rat. Regulation of antigen presentation activity by endogenous macrophage populations
    • HOLT, P.G., M.A. SCHON-HEGRAD & J. OLIVER. 1987. MHC class II antigen-bearing dendritic cells in pulmonary tissues of the rat. Regulation of antigen presentation activity by endogenous macrophage populations. J. Exp. Med. 167: 262-274.
    • (1987) J. Exp. Med. , vol.167 , pp. 262-274
    • Holt, P.G.1    Schon-Hegrad, M.A.2    Oliver, J.3
  • 32
    • 0024422064 scopus 로고
    • Characterization of sheep afferent lymph dendritic cells and their role in antigen carriage
    • BUJDOSO, R., J. HOPKINS, B.M. DUTIA, et al. 1989. Characterization of sheep afferent lymph dendritic cells and their role in antigen carriage. J. Exp. Med. 170: 1285-1302.
    • (1989) J. Exp. Med. , vol.170 , pp. 1285-1302
    • Bujdoso, R.1    Hopkins, J.2    Dutia, B.M.3
  • 33
    • 0027410872 scopus 로고
    • Antigen acquisition by dendritic cells: Intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo
    • LIU, L.M. & G.G. MACPHERSON. 1993. Antigen acquisition by dendritic cells: intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo. J. Exp. Med. 177: 1299-1307.
    • (1993) J. Exp. Med. , vol.177 , pp. 1299-1307
    • Liu, L.M.1    Macpherson, G.G.2
  • 34
    • 0025283350 scopus 로고
    • Dendritic cells are the principal cells in mouse spleen beating immunogenic fragments of foreign proteins
    • CROWLEY, M., K. INABA & R.M. STEINMAN. 1990. Dendritic cells are the principal cells in mouse spleen beating immunogenic fragments of foreign proteins. J. Exp. Med. 172: 383-386.
    • (1990) J. Exp. Med. , vol.172 , pp. 383-386
    • Crowley, M.1    Inaba, K.2    Steinman, R.M.3
  • 35
    • 0034614894 scopus 로고    scopus 로고
    • A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes
    • HUANG, F.-P., N. PLATT, M. WYKES, et al. 2000. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J. Exp. Med. 191: 435-442.
    • (2000) J. Exp. Med. , vol.191 , pp. 435-442
    • Huang, F.-P.1    Platt, N.2    Wykes, M.3
  • 36
    • 0022511898 scopus 로고
    • Langerhans cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody
    • KRAAL, G., M. BREEL, M. JANSE, et al. 1986. Langerhans cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody. J. Exp. Med. 163: 981-997.
    • (1986) J. Exp. Med. , vol.163 , pp. 981-997
    • Kraal, G.1    Breel, M.2    Janse, M.3
  • 37
    • 0028892479 scopus 로고
    • DEC-205, a 205 kDa protein abundant on mouse dendritic cells and thymic epithelium that is detected by the monoclonal antibody NLDC-145: Purification, characterization and N-terminal amino acid sequence
    • SWIGGARD, W.J., A. MIRZA, M.C. NUSSENZWEIG, et al. 1995. DEC-205, a 205 kDa protein abundant on mouse dendritic cells and thymic epithelium that is detected by the monoclonal antibody NLDC-145: purification, characterization and N-terminal amino acid sequence. Cell. Immunol. 165: 302-311.
    • (1995) Cell. Immunol. , vol.165 , pp. 302-311
    • Swiggard, W.J.1    Mirza, A.2    Nussenzweig, M.C.3
  • 38
    • 0029009977 scopus 로고
    • The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
    • JIANG, W., W.J. SWIGGARD, C. HEUFLER, et al. 1995. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 375: 151-155.
    • (1995) Nature , vol.375 , pp. 151-155
    • Jiang, W.1    Swiggard, W.J.2    Heufler, C.3
  • 39
    • 0034735552 scopus 로고    scopus 로고
    • The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments
    • MAHNKE, K., M. GUO, S. LEE, et al. 2000. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J. Cell Biol. 151: 673-683.
    • (2000) J. Cell Biol. , vol.151 , pp. 673-683
    • Mahnke, K.1    Guo, M.2    Lee, S.3
  • 40
    • 0019474658 scopus 로고
    • Studies on the capacity of B cells to serve as antigen-presenting cells
    • CHESNUT, R.W. & H.M. GREY. 1981. Studies on the capacity of B cells to serve as antigen-presenting cells. J. Immunol. 126: 1075-1079.
    • (1981) J. Immunol. , vol.126 , pp. 1075-1079
    • Chesnut, R.W.1    Grey, H.M.2
  • 41
    • 0033984930 scopus 로고    scopus 로고
    • Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules
    • VALLADEAU, J., O. RAVEL, C. DEZUTTER-DAMBUYANT, et al. 2000. Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules. Immunity 12: 71-81.
    • (2000) Immunity , vol.12 , pp. 71-81
    • Valladeau, J.1    Ravel, O.2    Dezutter-Dambuyant, C.3
  • 42
    • 0035889925 scopus 로고    scopus 로고
    • Immature human dendritic cells express asialoglycoprotein receptor isoforms for efficient receptor-mediated endocytosis
    • VALLADEAU, J., V. DUVERT-FRANCES, J.-J. PIN, et al. 2001. Immature human dendritic cells express asialoglycoprotein receptor isoforms for efficient receptor-mediated endocytosis. J. Immunol. 167: 5767-5774.
    • (2001) J. Immunol. , vol.167 , pp. 5767-5774
    • Valladeau, J.1    Duvert-Frances, V.2    Pin, J.-J.3
  • 43
    • 0036172314 scopus 로고    scopus 로고
    • DC-SIGN mediated internalization of HIV is required for trans-enhancement of T cell infection
    • KWON, D.S., G. GREGARIO, N. BITTON, et al. 2002. DC-SIGN mediated internalization of HIV is required for trans-enhancement of T cell infection. Immunity 16: 135-144.
    • (2002) Immunity , vol.16 , pp. 135-144
    • Kwon, D.S.1    Gregario, G.2    Bitton, N.3
  • 44
    • 0036499125 scopus 로고    scopus 로고
    • The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells
    • ENGERING, A., T.B. GEIJTENBEEK, S.J. VAN VLIET, et al. 2002. The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells. J. Immunol. 168: 2118-2126.
    • (2002) J. Immunol. , vol.168 , pp. 2118-2126
    • Engering, A.1    Geijtenbeek, T.B.2    Van Vliet, S.J.3
  • 45
    • 0035905321 scopus 로고    scopus 로고
    • BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen-capture and is a potent inhibitor of interferon-α/β induction
    • DZIONEK, A., Y. SOHMA, J. NAGAFUNE, et al. 2001. BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen-capture and is a potent inhibitor of interferon-α/β induction. J. Exp. Med. 194: 1823-1834.
    • (2001) J. Exp. Med. , vol.194 , pp. 1823-1834
    • Dzionek, A.1    Sohma, Y.2    Nagafune, J.3
  • 46
    • 0037141105 scopus 로고    scopus 로고
    • + dendritic cell subset selectively endocytoses dying cells in culture and in vivo
    • + dendritic cell subset selectively endocytoses dying cells in culture and in vivo. J. Exp. Med. 195: 1289-1302.
    • (2002) J. Exp. Med. , vol.195 , pp. 1289-1302
    • Iyoda, T.1    Shimoyama, S.2    Liu, K.3
  • 47
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • SAKAGUCHI, S. 2000. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101: 455-458.
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1
  • 48
    • 0029659056 scopus 로고    scopus 로고
    • The physiological role of regulatory T cells in the prevention of autoimmunity: The function of the thymus in the generation of the regulatory T cell subset
    • SAOUDI, A., B. SEDDON, V. HEATH, et al. 1996. The physiological role of regulatory T cells in the prevention of autoimmunity: the function of the thymus in the generation of the regulatory T cell subset. Immunol. Rev. 149: 195-216.
    • (1996) Immunol. Rev. , vol.149 , pp. 195-216
    • Saoudi, A.1    Seddon, B.2    Heath, V.3
  • 49
    • 0035806290 scopus 로고    scopus 로고
    • Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
    • JONULEIT, H., E. SCHMITT, M. STASSEN, et al. 2001. Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J. Exp. Med. 193: 1285-1294.
    • (2001) J. Exp. Med. , vol.193 , pp. 1285-1294
    • Jonuleit, H.1    Schmitt, E.2    Stassen, M.3
  • 50
    • 0035806323 scopus 로고    scopus 로고
    • Human CD25(+) CD4(+) T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
    • LEVINGS, M.K., R. SANGREGORIO & M.G. RONCAROLO. 2001. Human CD25(+) CD4(+) T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J. Exp. Med. 193: 1295-1302.
    • (2001) J. Exp. Med. , vol.193 , pp. 1295-1302
    • Levings, M.K.1    Sangregorio, R.2    Roncarolo, M.G.3
  • 51
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4(+) CD25(+) T cells with regulatory properties from human blood
    • DIECKMANN, D., H. PLOTTNER, S. BERCHTOLD, et al. 2001. Ex vivo isolation and characterization of CD4(+) CD25(+) T cells with regulatory properties from human blood. J. Exp. Med. 193: 1303-1310.
    • (2001) J. Exp. Med. , vol.193 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3
  • 52
    • 0035525739 scopus 로고    scopus 로고
    • Human CD4(+) CD25(+) cells: A naturally occurring population of regulatory T cells
    • NG, W.F., P.J. DUGGAN, F. PONCHEL, et al. 2001. Human CD4(+) CD25(+) cells: a naturally occurring population of regulatory T cells. Blood 98: 2736-2744.
    • (2001) Blood , vol.98 , pp. 2736-2744
    • Ng, W.F.1    Duggan, P.J.2    Ponchel, F.3
  • 54
    • 0028158319 scopus 로고
    • High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells
    • BACCHETTA, R., M. BIGLER, J.-L. TOURAINE, et al. 1994. High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells. J. Exp. Med. 179: 493-502.
    • (1994) J. Exp. Med. , vol.179 , pp. 493-502
    • Bacchetta, R.1    Bigler, M.2    Touraine, J.-L.3
  • 56
    • 0034613767 scopus 로고    scopus 로고
    • Induction of human IL-10-producing, non-proliferating CD4+ T cells with regulatory properties by repetitive stimulation with allogeneic immature dendritic cells
    • JONULEIT, H., E. SCHMITT, G. SCHULER, et al. 2000. Induction of human IL-10-producing, non-proliferating CD4+ T cells with regulatory properties by repetitive stimulation with allogeneic immature dendritic cells. J. Exp. Med. 192: 1213-1222.
    • (2000) J. Exp. Med. , vol.192 , pp. 1213-1222
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3
  • 57
    • 0035862333 scopus 로고    scopus 로고
    • Antigen specific inhibition of effector T cell function in humans after injection of immature dendritic cells
    • DHODAPKAR, M.V., R.M. STEINMAN, J. KRASOVSKY, et al. 2001. Antigen specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J. Exp. Med. 193: 233-238.
    • (2001) J. Exp. Med. , vol.193 , pp. 233-238
    • Dhodapkar, M.V.1    Steinman, R.M.2    Krasovsky, J.3
  • 58
    • 0034890907 scopus 로고    scopus 로고
    • Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
    • AKBARI, O., R.H. DEKRUYFF & D.T. UMETSU. 2001. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat. Immunol. 2: 725-731.
    • (2001) Nat. Immunol. , vol.2 , pp. 725-731
    • Akbari, O.1    Dekruyff, R.H.2    Umetsu, D.T.3
  • 59
    • 0035339884 scopus 로고    scopus 로고
    • IFN-α and IL-10 induce the differentiation of human type 1 T regulatory cells
    • LEVINGS, M.K., R. SANGREGORIO, F. GALBIATI, et al. 2001. IFN-α and IL-10 induce the differentiation of human type 1 T regulatory cells. J. Immunol. 166: 5530-5539.
    • (2001) J. Immunol. , vol.166 , pp. 5530-5539
    • Levings, M.K.1    Sangregorio, R.2    Galbiati, F.3
  • 60
    • 0035900481 scopus 로고    scopus 로고
    • Induction of dendritic cell differentiation by IFN-α in systemic lupus erythematosus
    • BLANCO, P., A.K. PALUCKA, M. GILL, et al. 2001. Induction of dendritic cell differentiation by IFN-α in systemic lupus erythematosus. Science 294: 1540-1543.
    • (2001) Science , vol.294 , pp. 1540-1543
    • Blanco, P.1    Palucka, A.K.2    Gill, M.3
  • 61
    • 0035801477 scopus 로고    scopus 로고
    • Overexpression of CD40 ligand in murine epidermis results in chronic skin inflammation and systemic autoimmunity
    • MEHLING, A., K. LOSER, G. VARGA, et al. 2001. Overexpression of CD40 ligand in murine epidermis results in chronic skin inflammation and systemic autoimmunity. J. Exp. Med. 194: 615-628.
    • (2001) J. Exp. Med. , vol.194 , pp. 615-628
    • Mehling, A.1    Loser, K.2    Varga, G.3
  • 62
    • 0027248719 scopus 로고
    • Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen-specific T cells
    • MOLL, H., H. FUCHS, C. BLANK, et al. 1993. Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen-specific T cells. Eur. J. Immunol. 23: 1595-1601.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1595-1601
    • Moll, H.1    Fuchs, H.2    Blank, C.3
  • 63
    • 0032547859 scopus 로고    scopus 로고
    • Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: Implications for the initiation of anti-Leishmania immunity
    • VON STEBUT, E., Y. BELKAID, T. JAKOB, et al. 1998. Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity. J. Exp. Med. 188: 1547-1552.
    • (1998) J. Exp. Med. , vol.188 , pp. 1547-1552
    • Von Stebut, E.1    Belkaid, Y.2    Jakob, T.3
  • 64
    • 0018887160 scopus 로고
    • Immunological regulation of experimental cutaneous leishmaniasis. III. Nature and significance of specific suppression of cell-mediated immunity in mice highly susceptible to Leishmania tropica
    • HOWARD, J.G., C. HALE & F.Y. LIEW. 1980. Immunological regulation of experimental cutaneous leishmaniasis. III. Nature and significance of specific suppression of cell-mediated immunity in mice highly susceptible to Leishmania tropica. J. Exp. Med. 152: 594-607.
    • (1980) J. Exp. Med. , vol.152 , pp. 594-607
    • Howard, J.G.1    Hale, C.2    Liew, F.Y.3
  • 65
    • 0022404444 scopus 로고
    • Prophylactic immunization against experimental leishmaniasis. V. Mechanism of the anti-protective blocking effect induced by subcutaneous immunization against Leishmania major infection
    • LIEW, F.Y., A. SINGLETON, E. CILLARI, et al. 1985. Prophylactic immunization against experimental leishmaniasis. V. Mechanism of the anti-protective blocking effect induced by subcutaneous immunization against Leishmania major infection. J. Immunol. 135: 2102-2107.
    • (1985) J. Immunol. , vol.135 , pp. 2102-2107
    • Liew, F.Y.1    Singleton, A.2    Cillari, E.3
  • 66
    • 0036789934 scopus 로고    scopus 로고
    • T cells from the tumor microenvironment of patients with progressive myeloma can generate strong, tumor-specific cytolytic responses to autologous, tumor-loaded dendritic cells
    • DHODAPKAR, M.V., J. KRASOVSKY & K. OLSON. 2002. T cells from the tumor microenvironment of patients with progressive myeloma can generate strong, tumor-specific cytolytic responses to autologous, tumor-loaded dendritic cells. Proc. Natl. Acad. Sci. USA 99: 13009-13013.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13009-13013
    • Dhodapkar, M.V.1    Krasovsky, J.2    Olson, K.3


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