메뉴 건너뛰기




Volumn 20, Issue 2, 2014, Pages 357-365

Autologous dendritic cell based adoptive immunotherapy of patients with colorectal cancer - A phase i-ii study

Author keywords

Autologous; Colorectal cancer; Dendritic cell; Vaccination

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; DENDRITIC CELL VACCINE; AUTOANTIGEN; TUMOR ANTIGEN;

EID: 84898782435     PISSN: 12194956     EISSN: 15322807     Source Type: Journal    
DOI: 10.1007/s12253-013-9704-3     Document Type: Article
Times cited : (21)

References (50)
  • 2
    • 0033572688 scopus 로고    scopus 로고
    • Report from the International Union Agaist Cancer (UICC) Tumor Biology Committee: UICC Workshop on the use of dendritic cells in cancer clinical trials
    • 10594863 10.1002/(SICI)1097-0142(19991215)86:12<2674: AID-CNCR12>3.0.CO;2-Z
    • Salgaller ML, Thurner M, Bartsch G, Boynton AL, Murphy GP (1999) Report from the International Union Agaist Cancer (UICC) Tumor Biology Committee: UICC Workshop on the use of dendritic cells in cancer clinical trials. Cancer 86:2674-2683
    • (1999) Cancer , vol.86 , pp. 2674-2683
    • Salgaller, M.L.1    Thurner, M.2    Bartsch, G.3    Boynton, A.L.4    Murphy, G.P.5
  • 3
    • 0033572718 scopus 로고    scopus 로고
    • The ongoing evolution of dendritic cell therapy
    • 10.1002/(SICI)1097-0142(19991215)86:12<2593: AID-CNCR2>3.3.CO;2-Z
    • Sokolof MH, Vogelzang N (1999) The ongoing evolution of dendritic cell therapy. Cancer 86:2593-2596
    • (1999) Cancer , vol.86 , pp. 2593-2596
    • Sokolof, M.H.1    Vogelzang, N.2
  • 4
    • 0344039007 scopus 로고
    • Cytolytic T-cell clones against an autologous human melanoma: Specificity study and definition of three antigens by immunoselection
    • 287007 2784858 10.1073/pnas.86.8.2804
    • Knuth A, Wölfel T, Klehmann E, Boon T, Büschenfelde KM (1989) Cytolytic T-cell clones against an autologous human melanoma: specificity study and definition of three antigens by immunoselection. Proc Natl Acad Sci U S A 86:2804-2808
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 2804-2808
    • Knuth, A.1    Wölfel, T.2    Klehmann, E.3    Boon, T.4    Büschenfelde, K.M.5
  • 5
    • 0037244743 scopus 로고    scopus 로고
    • Rational approaches to human cancer immunotherapy
    • 10.1189/jlb.0502261
    • Davis ID, Jefford M, Parente P, Cebon J (2003) Rational approaches to human cancer immunotherapy. J Leuk Biol 73:3-29
    • (2003) J Leuk Biol , vol.73 , pp. 3-29
    • Davis, I.D.1    Jefford, M.2    Parente, P.3    Cebon, J.4
  • 6
    • 0036322003 scopus 로고    scopus 로고
    • The role of CD8+ T cells in immune responses to colorectal cancer
    • 10.1007/s00262-002-0276-4
    • Liviu V, Titu E, John R, Monson E, Greenman J (2002) The role of CD8+ T cells in immune responses to colorectal cancer. Cancer Immunol Immunother 51:235-247
    • (2002) Cancer Immunol Immunother , vol.51 , pp. 235-247
    • Liviu, V.1    Titu, E.2    John, R.3    Monson, E.4    Greenman, J.5
  • 7
    • 0025030522 scopus 로고
    • Presentation of exogenous antigen with class i major histocompatibility complex molecules
    • 2392683 10.1126/science.2392683
    • Rock KL, Gamble S, Rothstein L (1990) Presentation of exogenous antigen with class I major histocompatibility complex molecules. Science 249:918-921
    • (1990) Science , vol.249 , pp. 918-921
    • Rock, K.L.1    Gamble, S.2    Rothstein, L.3
  • 9
    • 2642679384 scopus 로고    scopus 로고
    • Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro: Enhancement by co-transfection of genes encoding the Th1-biasing cytokines IL-12 and IFN alfa
    • Tuting T, Wilson CC, Martin DM, Kasamon YL, Rowles J, Ma DI, Slingluff CLJ, Wagner SN, Bruggen P, Baar J, Lotze MT, Storkus WJ (1998) Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro: enhancement by co-transfection of genes encoding the Th1-biasing cytokines IL-12 and IFN alfa. J Immunol Methods 160:1139-1147
    • (1998) J Immunol Methods , vol.160 , pp. 1139-1147
    • Tuting, T.1    Wilson, C.C.2    Martin, D.M.3    Kasamon, Y.L.4    Rowles, J.5    Ma, D.I.6    Slingluff, C.L.J.7    Wagner, S.N.8    Bruggen, P.9    Baar, J.10    Lotze, M.T.11    Storkus, W.J.12
  • 10
    • 0033514937 scopus 로고    scopus 로고
    • Systemic adminstration of interleukin 2 enhances the therapeutic effficacy of dendritic cell-based tumor vaccine
    • 26772 10051630 10.1073/pnas.96.5.2268
    • Shimizu K, Fields RC, Giedlin M, Mule JJ (1999) Systemic adminstration of interleukin 2 enhances the therapeutic effficacy of dendritic cell-based tumor vaccine. Proc Natl Acad Sci USA 96:2268-2273
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2268-2273
    • Shimizu, K.1    Fields, R.C.2    Giedlin, M.3    Mule, J.J.4
  • 11
    • 0033989932 scopus 로고    scopus 로고
    • Absence of CD83(+)-positive mature and activated dendritic cells at cancer nodules from patients with hepatocellular carcinoma: Relevance to hepatocarcinogenesis
    • 10680592 10.1016/S0304-3835(99)00312-2
    • Chen S, Akbar SM, Tanimoto K, Ninomiya T, Iuchi H, Michitaka K, Horiike N, Onji M (2000) Absence of CD83(+)-positive mature and activated dendritic cells at cancer nodules from patients with hepatocellular carcinoma: relevance to hepatocarcinogenesis. Cancer Lett 148:49-57
    • (2000) Cancer Lett , vol.148 , pp. 49-57
    • Chen, S.1    Akbar, S.M.2    Tanimoto, K.3    Ninomiya, T.4    Iuchi, H.5    Michitaka, K.6    Horiike, N.7    Onji, M.8
  • 12
    • 42149156663 scopus 로고    scopus 로고
    • Immunotherapy of hematological malignancies using dendritic cells
    • 18390412
    • Van-de-Velde AL, Berneman ZN, Van-Tendeloo VF (2008) Immunotherapy of hematological malignancies using dendritic cells. Bull Cancer 95:320-326
    • (2008) Bull Cancer , vol.95 , pp. 320-326
    • Van-De-Velde, A.L.1    Berneman, Z.N.2    Van-Tendeloo, V.F.3
  • 13
  • 16
    • 51349160589 scopus 로고    scopus 로고
    • Dendritic cell-based cancer vaccination: Quo vadis?
    • 18767953 10.1586/14760584.7.7.1041
    • Dauer M, Schnurr M, Eigler A (2008) Dendritic cell-based cancer vaccination: quo vadis? Expert Rev Vaccines 7:1041-1053
    • (2008) Expert Rev Vaccines. , vol.7 , pp. 1041-1053
    • Dauer, M.1    Schnurr, M.2    Eigler, A.3
  • 18
    • 36249013789 scopus 로고    scopus 로고
    • Dendritic cells in cancer immunotherapy
    • 18037410 10.1016/S0065-230X(07)99006-5
    • Vulink A, Radford KJ, Melief C, Hart DN (2008) Dendritic cells in cancer immunotherapy. Adv Cancer Res 99:363-407
    • (2008) Adv Cancer Res , vol.99 , pp. 363-407
    • Vulink, A.1    Radford, K.J.2    Melief, C.3    Hart, D.N.4
  • 19
    • 81855166109 scopus 로고    scopus 로고
    • Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer
    • 3170420 21909876 10.1007/s12307-010-0052-5
    • Erreni M, Mantovani A, Allavena P (2011) Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer. Cancer Microenviron 4:141-154
    • (2011) Cancer Microenviron , vol.4 , pp. 141-154
    • Erreni, M.1    Mantovani, A.2    Allavena, P.3
  • 20
    • 75149189004 scopus 로고    scopus 로고
    • Role of systemic inflammatory response in predicting survival in patients with primary operable cancer
    • 20021215 10.2217/fon.09.136
    • Roxburgh C, McMillan D (2010) Role of systemic inflammatory response in predicting survival in patients with primary operable cancer. Future Oncol 6:149-163
    • (2010) Future Oncol , vol.6 , pp. 149-163
    • Roxburgh, C.1    McMillan, D.2
  • 21
    • 84861194756 scopus 로고    scopus 로고
    • The role of the in situ local inflammatory response in predicting recurrence and survival in patients with primary operable colorectal cancer
    • 10.1016/j.ctrv.2011.09.001 21945823 10.1016/j.ctrv.2011.09.001 Epub 2011 Sep 25
    • Roxburgh C, McMillan D (2012) The role of the in situ local inflammatory response in predicting recurrence and survival in patients with primary operable colorectal cancer. Cancer Treat Rev 38(5):451-466. doi: 10.1016/j.ctrv.2011.09. 001, Epub 2011 Sep 25
    • (2012) Cancer Treat Rev , vol.38 , Issue.5 , pp. 451-466
    • Roxburgh, C.1    McMillan, D.2
  • 22
    • 84898815745 scopus 로고    scopus 로고
    • database-online Last Medical Review: 05/24/2012; Last Revised: 01/17/2013
    • database-online http://www.cancer.org/Cancer/ColonandRectumCancer/ DetailedGuide/colorectal-cancer-survival-rates. Last Medical Review: 05/24/2012; Last Revised: 01/17/2013
  • 23
    • 77958454596 scopus 로고    scopus 로고
    • Designing vaccines based on biology of human dendritic cell subsets
    • 2975953 21029958 10.1016/j.immuni.2010.10.007
    • Palucka K, Banchereau J, Mellman I (2010) Designing vaccines based on biology of human dendritic cell subsets. Immunity 33:464-478
    • (2010) Immunity , vol.33 , pp. 464-478
    • Palucka, K.1    Banchereau, J.2    Mellman, I.3
  • 24
    • 0034918104 scopus 로고    scopus 로고
    • Dendritic cells: On the move from bench to bedside
    • 11433329 10.1038/89863
    • Nestle F, Banchereau J, Hart D (2001) Dendritic cells: on the move from bench to bedside. Nat Med 7:761-765
    • (2001) Nat Med , vol.7 , pp. 761-765
    • Nestle, F.1    Banchereau, J.2    Hart, D.3
  • 25
    • 2442647551 scopus 로고    scopus 로고
    • Dendritic cell immunotherapy: Mapping the way
    • 15122249 10.1038/nm1039
    • Figdor C, Jd V, Lesterhuis W, Melief C (2004) Dendritic cell immunotherapy: mapping the way. Nat Med 10:475-480
    • (2004) Nat Med , vol.10 , pp. 475-480
    • Figdor, C.1    Jd, V.2    Lesterhuis, W.3    Melief, C.4
  • 26
    • 0034023485 scopus 로고    scopus 로고
    • Mature dendritic cells boost functionally superior CD8(+) T-cell in humans without foreign helper epitopes
    • 10.1172/JCI9051
    • Dhodapkar MV, Krasovsky J, Steinman RM, Bhardwaj N (2000) Mature dendritic cells boost functionally superior CD8(+) T-cell in humans without foreign helper epitopes. J Clin Invest 105:9-14
    • (2000) J Clin Invest , vol.105 , pp. 9-14
    • Dhodapkar, M.V.1    Krasovsky, J.2    Steinman, R.M.3    Bhardwaj, N.4
  • 29
    • 0037141023 scopus 로고    scopus 로고
    • Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature cryopreserved, peptide-loaded monocyte-derived dendritic cells
    • 10.1084/jem.20012100
    • Schuler-Thurnmer B, Schultz ES, Berger TG, Weinlich G, Ebner S, Woerl P, Bender A, Feuerstein B, Fritsch PO, Romani N, Schuler G (2002) Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature cryopreserved, peptide-loaded monocyte-derived dendritic cells. J Exp Med 195:1279-1288
    • (2002) J Exp Med , vol.195 , pp. 1279-1288
    • Schuler-Thurnmer, B.1    Schultz, E.S.2    Berger, T.G.3    Weinlich, G.4    Ebner, S.5    Woerl, P.6    Bender, A.7    Feuerstein, B.8    Fritsch, P.O.9    Romani, N.10    Schuler, G.11
  • 30
    • 0042922810 scopus 로고    scopus 로고
    • Regulation of dendritic cell migration to the draining lymph node: Impact on T lymphocyte traffic and priming
    • 2194169 12925677 10.1084/jem.20030448
    • Martin-Fontecha A, Sebastiani S, Höpken U, Uguccioni M, Lipp M, Lanzavecchia A, Sallusto F (2003) Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med 198:615-621
    • (2003) J Exp Med , vol.198 , pp. 615-621
    • Martin-Fontecha, A.1    Sebastiani, S.2    Höpken, U.3    Uguccioni, M.4    Lipp, M.5    Lanzavecchia, A.6    Sallusto, F.7
  • 31
    • 0039782448 scopus 로고    scopus 로고
    • The use of dendritic cells in cancer therapy
    • 11905751 10.1016/S1470-2045(00)00389-2
    • Jefford M, Maraskovsky E, Cebon J, Davies ID (2001) The use of dendritic cells in cancer therapy. Lancet Oncol 2(6):343-353
    • (2001) Lancet Oncol , vol.2 , Issue.6 , pp. 343-353
    • Jefford, M.1    Maraskovsky, E.2    Cebon, J.3    Davies, I.D.4
  • 32
    • 0035889647 scopus 로고    scopus 로고
    • Active immunization against cancer with dendritic cells: The near future
    • 11745430 10.1002/ijc.1503
    • Steinman RM, Dhodapkar M (2001) Active immunization against cancer with dendritic cells: the near future. Int J Cancer 94:459-473
    • (2001) Int J Cancer , vol.94 , pp. 459-473
    • Steinman, R.M.1    Dhodapkar, M.2
  • 33
    • 0345865089 scopus 로고    scopus 로고
    • Dendritic cells: A journey from laboratory to clinic
    • 14699398 10.1038/ni0104-7
    • Cerundolo V, Hermans I, Salio M (2004) Dendritic cells: a journey from laboratory to clinic. Nat Immunol 5:7-10
    • (2004) Nat Immunol , vol.5 , pp. 7-10
    • Cerundolo, V.1    Hermans, I.2    Salio, M.3
  • 34
    • 1642338349 scopus 로고    scopus 로고
    • Clinical applications of dendritic cell vaccination in the treatment of cancer
    • 14648069 10.1007/s00262-003-0432-5
    • Cranmer L, Trevor K, Hersh E (2004) Clinical applications of dendritic cell vaccination in the treatment of cancer. Cancer Immunol Immunother 53:275-306
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 275-306
    • Cranmer, L.1    Trevor, K.2    Hersh, E.3
  • 36
    • 9644303122 scopus 로고    scopus 로고
    • Colorectal cancer vaccines: Principles, results, and perspectives
    • 15578520 10.1053/j.gastro.2004.07.012
    • Mocellin S, Rossi C, Lise M, Nitti D (2004) Colorectal cancer vaccines: principles, results, and perspectives. Gastroenterology 127:1821-1837
    • (2004) Gastroenterology , vol.127 , pp. 1821-1837
    • Mocellin, S.1    Rossi, C.2    Lise, M.3    Nitti, D.4
  • 37
    • 21344459458 scopus 로고    scopus 로고
    • Therapeutic vaccination in patients with gastrointestinal malignancies. A review of immunological and clinical results
    • 15829493 10.1093/annonc/mdi192
    • Mosolits S, Ullenhag G, Mellstedt H (2005) Therapeutic vaccination in patients with gastrointestinal malignancies. A review of immunological and clinical results. Ann Oncol 16:847-862
    • (2005) Ann Oncol , vol.16 , pp. 847-862
    • Mosolits, S.1    Ullenhag, G.2    Mellstedt, H.3
  • 38
    • 33744815600 scopus 로고    scopus 로고
    • Clinical and immunologic responses to active specific cancer vaccines in human colorectal cancer
    • 16707603 10.1158/1078-0432.CCR-05-2788
    • Nagorsen D, Thiel E (2006) Clinical and immunologic responses to active specific cancer vaccines in human colorectal cancer. Clin Cancer Res 12:3064-3069
    • (2006) Clin Cancer Res , vol.12 , pp. 3064-3069
    • Nagorsen, D.1    Thiel, E.2
  • 39
    • 0346096827 scopus 로고    scopus 로고
    • The first 1000 dendritic cell vaccinees
    • 14735692 10.1081/CNV-120025091
    • Ridgway D (2003) The first 1000 dendritic cell vaccinees. Cancer Invest 21:873-886
    • (2003) Cancer Invest , vol.21 , pp. 873-886
    • Ridgway, D.1
  • 40
    • 2142646416 scopus 로고    scopus 로고
    • Development of effective immunotherapy for the treatment of patients with cancer
    • 1471995 15110801 10.1016/j.jamcollsurg.2004.01.025
    • Rosenberg S (2004) Development of effective immunotherapy for the treatment of patients with cancer. J Am Coll Surg 198:685-696
    • (2004) J Am Coll Surg , vol.198 , pp. 685-696
    • Rosenberg, S.1
  • 41
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • 1435696 15340416 10.1038/nm1100
    • Rosenberg S, Yang J, Restifo N (2004) Cancer immunotherapy: moving beyond current vaccines. Nat Med 10:909-915
    • (2004) Nat Med , vol.10 , pp. 909-915
    • Rosenberg, S.1    Yang, J.2    Restifo, N.3
  • 46
    • 84862126124 scopus 로고    scopus 로고
    • Regulation of suppressive function of myeloid-derived suppressor cells by CD4(+) T cells
    • 10.1016/j.semcancer.2012.01.010 3349790 22313876 10.1016/j.semcancer. 2012.01.010 Epub 2012 Jan 31
    • Nagaraj S, Gabrilovich DI (2012) Regulation of suppressive function of myeloid-derived suppressor cells by CD4(+) T cells. Semin Cancer Biol 22(4):282-288. doi: 10.1016/j.semcancer.2012.01.010, Epub 2012 Jan 31
    • (2012) Semin Cancer Biol , vol.22 , Issue.4 , pp. 282-288
    • Nagaraj, S.1    Gabrilovich, D.I.2
  • 47
    • 20144375359 scopus 로고    scopus 로고
    • CD4∈+∈CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice
    • 15899788 10.1158/0008-5472.CAN-04-3104
    • Erdman S, Sohn J, Rao V, Nambiar P, Ge Z, Fox J, Schauer D (2005) CD4∈+∈CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice. Cancer Res 65:3998-4004
    • (2005) Cancer Res , vol.65 , pp. 3998-4004
    • Erdman, S.1    Sohn, J.2    Rao, V.3    Nambiar, P.4    Ge, Z.5    Fox, J.6    Schauer, D.7
  • 49
    • 38649136919 scopus 로고    scopus 로고
    • Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: Relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival
    • Nagorsen D, Voigt S, Berg E, Stein H, Thiel E, Loddenkemper C (2007) Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival. J Transl Med 29:62
    • (2007) J Transl Med , vol.29 , pp. 62
    • Nagorsen, D.1    Voigt, S.2    Berg, E.3    Stein, H.4    Thiel, E.5    Loddenkemper, C.6
  • 50
    • 0035554675 scopus 로고    scopus 로고
    • The risk of autoimmunity asssociated with tumor immunotherapy
    • 11526387 10.1038/ni0901-789
    • Gilboa E (2001) The risk of autoimmunity asssociated with tumor immunotherapy. Nat Immunol 2:789-792
    • (2001) Nat Immunol , vol.2 , pp. 789-792
    • Gilboa, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.