Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 6, 2011, Pages 2384-2389

  Idoyaga, Juliana ^a   Lubkin, Ashira ^a   Fiorese, Christopher ^a   Lahoud, Mireille H ^b,c   Caminschi, Irina ^b,c   Huang, Yaoxing ^d   Rodriguez, Anthony ^a   Clausen, Björn E ^e   Park, Chae Gyu ^a   Trumpfheller, Christine ^a   Steinmana, Ralph M ^a,b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d AARON DIAMOND AIDS RESEARCH CENTER   (United States)

^e ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Antigen presentation; C type lectins; Cross priming

Indexed keywords

CD205 ANTIGEN; CD8 ANTIGEN; CLEC9A RECEPTOR; GAG PROTEIN; LANGERIN; LYMPHOCYTE ANTIGEN; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN PRESENTATION; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CROSS PRESENTATION; DENDRITIC CELL; HEAVY CHAIN; IMMUNIZATION; IMMUNOGENICITY; IN VIVO STUDY; LYMPHOCYTE SUBPOPULATION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; PROTEIN TRANSPORT; TH1 CELL;

AIDS VACCINES; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD8; ANTIGENS, SURFACE; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; HIV CORE PROTEIN P24; IMMUNITY, CELLULAR; LECTINS, C-TYPE; MANNOSE-BINDING LECTINS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; TH1 CELLS;

MUS;

EID: 79952294318     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1019547108     Document Type: Article

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