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Volumn 177, Issue 12, 2006, Pages 8410-8421

Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT; CD4 ANTIGEN; CD40 ANTIBODY; CELL RECEPTOR; CYTOKINE; DEC205 RECEPTOR ANTIBODY; DENDRITIC CELL VACCINE; DNA VACCINE; GAMMA INTERFERON; HUMAN SURVIVIN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; MOUSE SURVIVIN; PLASMID DNA; POLYINOSINIC POLYCYTIDYLIC ACID; RECEPTOR ANTIBODY; SURVIVIN; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA;

EID: 33845425072     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.12.8410     Document Type: Article
Times cited : (62)

References (89)
  • 1
    • 0141720783 scopus 로고    scopus 로고
    • Cancer vaccines: Between the idea and the reality
    • Finn, O. J. 2003. Cancer vaccines: between the idea and the reality. Nat. Rev. Immunol. 3: 630-641.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 630-641
    • Finn, O.J.1
  • 2
    • 0028127304 scopus 로고
    • Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma
    • Maloney, D. G., T. M. Liles, D. K. Czerwinski, C. Waldichuk, J. Rosenberg, A. Grillo-Lopez, and R. Levy. 1994. Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma. Blood 84: 2457-2466.
    • (1994) Blood , vol.84 , pp. 2457-2466
    • Maloney, D.G.1    Liles, T.M.2    Czerwinski, D.K.3    Waldichuk, C.4    Rosenberg, J.5    Grillo-Lopez, A.6    Levy, R.7
  • 3
    • 0037819344 scopus 로고    scopus 로고
    • An overview of the current clinical use of the anti-CD20 monoclonal antibody rituximab
    • Boye, J., T. Elter, and A. Engert. 2003. An overview of the current clinical use of the anti-CD20 monoclonal antibody rituximab. Ann. Oncol. 14: 520-535.
    • (2003) Ann. Oncol. , vol.14 , pp. 520-535
    • Boye, J.1    Elter, T.2    Engert, A.3
  • 10
    • 0028205094 scopus 로고
    • In vivo priming of two distinct antitumor effector populations: The role of MHC class I expression
    • Levitsky, H. I., A. Lazenby, R. J. Hayashi, and D. M. Pardoll. 1994. In vivo priming of two distinct antitumor effector populations: the role of MHC class I expression. J. Exp. Med. 179: 1215-1224.
    • (1994) J. Exp. Med. , vol.179 , pp. 1215-1224
    • Levitsky, H.I.1    Lazenby, A.2    Hayashi, R.J.3    Pardoll, D.M.4
  • 11
    • 0033662405 scopus 로고    scopus 로고
    • + T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN-γ receptor expression by nonhematopoietic cells
    • + T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN-γ receptor expression by nonhematopoietic cells. Immunity 12: 677-686.
    • (2000) Immunity , vol.12 , pp. 677-686
    • Qin, Z.1    Blankenstein, T.2
  • 15
    • 0035348175 scopus 로고    scopus 로고
    • Memory CD8+ T cell differentiation: Initial antigen encounter triggers a developmental program in naive cells
    • Kaech, S. M., and R. Ahmed. 2001. Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nat. Immunol. 2: 415-422.
    • (2001) Nat. Immunol. , vol.2 , pp. 415-422
    • Kaech, S.M.1    Ahmed, R.2
  • 16
    • 0035348246 scopus 로고    scopus 로고
    • Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation
    • van Stipdonk, M. J., E. E. Lemmens, and S. P. Schoenberger. 2001. Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation. Nat. Immunol. 2: 423-429.
    • (2001) Nat. Immunol. , vol.2 , pp. 423-429
    • Van Stipdonk, M.J.1    Lemmens, E.E.2    Schoenberger, S.P.3
  • 20
    • 0037267333 scopus 로고    scopus 로고
    • Validating survivin as a cancer therapeutic target
    • Altieri, D. C. 2003. Validating survivin as a cancer therapeutic target. Nat. Rev. Cancer 3: 46-54.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 46-54
    • Altieri, D.C.1
  • 21
    • 0035204883 scopus 로고    scopus 로고
    • The molecular basis and potential role of survivin in cancer diagnosis and therapy
    • Altieri, D. C. 2001. The molecular basis and potential role of survivin in cancer diagnosis and therapy. Trends Mol. Med. 7: 542-547.
    • (2001) Trends Mol. Med. , vol.7 , pp. 542-547
    • Altieri, D.C.1
  • 24
    • 0034597594 scopus 로고    scopus 로고
    • Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
    • Uren, A. G., L. Wong, M. Pakusch, K. J. Fowler, F. J. Burrows, D. L. Vaux, and K. H. Choo. 2000. Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr. Biol. 10: 1319-1328.
    • (2000) Curr. Biol. , vol.10 , pp. 1319-1328
    • Uren, A.G.1    Wong, L.2    Pakusch, M.3    Fowler, K.J.4    Burrows, F.J.5    Vaux, D.L.6    Choo, K.H.7
  • 25
    • 0032403126 scopus 로고    scopus 로고
    • IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs
    • Tamm, I., Y. Wang, E. Sausville, D. A. Scudiero, N. Vigna, T. Oltersdorf, and J. C. Reed. 1998. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res. 58: 5315-5320.
    • (1998) Cancer Res. , vol.58 , pp. 5315-5320
    • Tamm, I.1    Wang, Y.2    Sausville, E.3    Scudiero, D.A.4    Vigna, N.5    Oltersdorf, T.6    Reed, J.C.7
  • 28
    • 0342657718 scopus 로고    scopus 로고
    • A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy
    • Olie, R. A., A. P. Simoes-Wust, B. Baumann, S. H. Leech, D. Fabbro, R. A. Stahel, and U. Zangemeister-Wittke. 2000. A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Res. 60: 2805-2809.
    • (2000) Cancer Res. , vol.60 , pp. 2805-2809
    • Olie, R.A.1    Simoes-Wust, A.P.2    Baumann, B.3    Leech, S.H.4    Fabbro, D.5    Stahel, R.A.6    Zangemeister-Wittke, U.7
  • 29
    • 12344250640 scopus 로고    scopus 로고
    • Survivin antisense compound inhibits proliferation and promotes apoptosis in liver cancer cells
    • Dai, D. J., C. D. Lu, R. Y. Lai, J. M. Guo, H. Meng, W. S. Chen, and J. Gu. 2005. Survivin antisense compound inhibits proliferation and promotes apoptosis in liver cancer cells. World J. Gastraenterol. 11: 193-199.
    • (2005) World J. Gastraenterol. , vol.11 , pp. 193-199
    • Dai, D.J.1    Lu, C.D.2    Lai, R.Y.3    Guo, J.M.4    Meng, H.5    Chen, W.S.6    Gu, J.7
  • 30
    • 0037817310 scopus 로고    scopus 로고
    • Therapeutic targeting of the survivin pathway in cancer: Initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis
    • Blanc-Brude, O. P., M. Mesri, N. R. Wall, J. Plescia, T. Dohi, and D. C. Altieri. 2003. Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis. Clin. Cancer Res. 9: 2683-2692.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2683-2692
    • Blanc-Brude, O.P.1    Mesri, M.2    Wall, N.R.3    Plescia, J.4    Dohi, T.5    Altieri, D.C.6
  • 35
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
    • Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R. M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176: 1693-1702.
    • (1992) J. Exp. Med. , vol.176 , pp. 1693-1702
    • Inaba, K.1    Inaba, M.2    Romani, N.3    Aya, H.4    Deguchi, M.5    Ikehara, S.6    Muramatsu, S.7    Steinman, R.M.8
  • 36
    • 0028041170 scopus 로고
    • Monoclonal antibodies to murine CD40 define two distinct functional epitopes
    • Heath, A. W., W. W. Wu, and M. C. Howard. 1994. Monoclonal antibodies to murine CD40 define two distinct functional epitopes. Eur. J. Immunol. 24: 1828-1834.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1828-1834
    • Heath, A.W.1    Wu, W.W.2    Howard, M.C.3
  • 37
    • 0141763655 scopus 로고    scopus 로고
    • Induction of antitumour immunity using survivin peptide-pulsed dendritic cells in a murine lymphoma model
    • Siegel, S., A. Wagner, N. Schmitz, and M. Zeis. 2003. Induction of antitumour immunity using survivin peptide-pulsed dendritic cells in a murine lymphoma model. Br. J. Haematol 122: 911-914.
    • (2003) Br. J. Haematol , vol.122 , pp. 911-914
    • Siegel, S.1    Wagner, A.2    Schmitz, N.3    Zeis, M.4
  • 38
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor-anti-) monoclonal antibody
    • Onizuka, S., I. Tawara, J. Shimizu, S. Sakaguchi, T. Fujita, and E. Nakayama. 1999. Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor-anti-) monoclonal antibody. Cancer Res. 59: 3128-3133.
    • (1999) Cancer Res. , vol.59 , pp. 3128-3133
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3    Sakaguchi, S.4    Fujita, T.5    Nakayama, E.6
  • 39
    • 11844264031 scopus 로고    scopus 로고
    • Cutting edge: MHC class II-restricted killing in vivo during viral infection
    • Jellison, E. R., S. K. Kim, and R. M. Welsh. 2005. Cutting edge: MHC class II-restricted killing in vivo during viral infection. J. Immunol. 174: 614-618.
    • (2005) J. Immunol. , vol.174 , pp. 614-618
    • Jellison, E.R.1    Kim, S.K.2    Welsh, R.M.3
  • 40
    • 0031753867 scopus 로고    scopus 로고
    • Gene transfer into muscle by electroporation in vivo
    • Aihara, H., and J. Miyazaki. 1998. Gene transfer into muscle by electroporation in vivo. Nat. Biotechnol. 16: 867-870.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 867-870
    • Aihara, H.1    Miyazaki, J.2
  • 41
    • 18644379809 scopus 로고    scopus 로고
    • Electroporation as a "prime/boost" strategy for naked DNA vaccination against a tumor antigen
    • Buchan, S., E. Gronevik, I. Mathiesen, C. A. King, F. K. Stevenson, and J. Rice. 2005. Electroporation as a "prime/boost" strategy for naked DNA vaccination against a tumor antigen. J. Immunol. 174: 6292-6298.
    • (2005) J. Immunol. , vol.174 , pp. 6292-6298
    • Buchan, S.1    Gronevik, E.2    Mathiesen, I.3    King, C.A.4    Stevenson, F.K.5    Rice, J.6
  • 42
    • 0024571804 scopus 로고
    • Does T-cell tolerance require a dedicated antigen-presenting cell?
    • Matzinger, P., and S. Guerder. 1989. Does T-cell tolerance require a dedicated antigen-presenting cell? Nature 338: 74-76.
    • (1989) Nature , vol.338 , pp. 74-76
    • Matzinger, P.1    Guerder, S.2
  • 43
    • 0033571105 scopus 로고    scopus 로고
    • + T cells: A common basis between tumor immunity and autoimmunity
    • + T cells: a common basis between tumor immunity and autoimmunity. J. Immunol. 163: 5211-5218.
    • (1999) J. Immunol. , vol.163 , pp. 5211-5218
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 46
    • 0028328488 scopus 로고
    • Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity
    • Stalder, T., S. Hahn, and P. Erb. 1994. Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity. J. Immunol. 152: 1127-1133.
    • (1994) J. Immunol. , vol.152 , pp. 1127-1133
    • Stalder, T.1    Hahn, S.2    Erb, P.3
  • 47
    • 0030047314 scopus 로고    scopus 로고
    • + CTL that utilizes a perform- rather than a Fas ligand-dependent cytotoxic mechanism
    • + CTL that utilizes a perform- rather than a Fas ligand-dependent cytotoxic mechanism. J. Immunol. 156: 153-159.
    • (1996) J. Immunol. , vol.156 , pp. 153-159
    • Williams, N.S.1    Engelhard, V.H.2
  • 48
    • 23044450840 scopus 로고    scopus 로고
    • Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells
    • Spiotto, M. T., and H. Schreiber. 2005. Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells. Cancer Immun. 5: 8.
    • (2005) Cancer Immun. , vol.5 , pp. 8
    • Spiotto, M.T.1    Schreiber, H.2
  • 50
    • 0037627415 scopus 로고    scopus 로고
    • Genetic changes occurring in established tumors rapidly stimulate new antibody responses
    • Spiotto, M. T., M. A. Reth, and H. Schreiber. 2003. Genetic changes occurring in established tumors rapidly stimulate new antibody responses. Proc. Natl. Acad. Sci. USA 100: 5425-5430.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5425-5430
    • Spiotto, M.T.1    Reth, M.A.2    Schreiber, H.3
  • 53
    • 0035339389 scopus 로고    scopus 로고
    • Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC-1 transgenic mice with different potential for tumor rejection
    • Soares, M. M., V. Mehta, and O. J. Finn, 2001. Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC-1 transgenic mice with different potential for tumor rejection. J. Immunol. 166: 6555-6563.
    • (2001) J. Immunol. , vol.166 , pp. 6555-6563
    • Soares, M.M.1    Mehta, V.2    Finn, O.J.3
  • 54
    • 0033083229 scopus 로고    scopus 로고
    • Induction of protective host immunity to carcinoembryonic antigen (CEA), a self-antigen in CEA transgenic mice, by immunizing with a recombinant vaccinia-CEA virus
    • Kass, E., J. Schlom, J. Thompson, F. Guadagni, P. Graziano, and J. W. Greiner. 1999. Induction of protective host immunity to carcinoembryonic antigen (CEA), a self-antigen in CEA transgenic mice, by immunizing with a recombinant vaccinia-CEA virus. Cancer Res. 59: 676-683.
    • (1999) Cancer Res. , vol.59 , pp. 676-683
    • Kass, E.1    Schlom, J.2    Thompson, J.3    Guadagni, F.4    Graziano, P.5    Greiner, J.W.6
  • 55
    • 0035360260 scopus 로고    scopus 로고
    • Synergy of vaccine strategies to amplify antigen-specific immune responses and antitumor effects
    • Grosenbach, D. W., J. C. Barrientos, J. Schlom, and J. W. Hodge. 2001. Synergy of vaccine strategies to amplify antigen-specific immune responses and antitumor effects. Cancer Res. 61: 4497-4505.
    • (2001) Cancer Res. , vol.61 , pp. 4497-4505
    • Grosenbach, D.W.1    Barrientos, J.C.2    Schlom, J.3    Hodge, J.W.4
  • 56
    • 0034507693 scopus 로고    scopus 로고
    • Impact of negative selection on the T cell repertoire reactive to a self-peptide: A large fraction of T cell clones escapes clonal detection
    • Bouneaud, C., P. Kourilsky, and P. Bousso. 2000. Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal detection. Immunity 13: 829-840.
    • (2000) Immunity , vol.13 , pp. 829-840
    • Bouneaud, C.1    Kourilsky, P.2    Bousso, P.3
  • 57
    • 0036131962 scopus 로고    scopus 로고
    • Induction of immune tolerance toward tumor-associated-antigens enables growth of human hepatoma in mice
    • Gotsman, I., D. Israeli, R. Alper, E. Rabbani, D. Engelhardt, and Y. Ilan. 2002. Induction of immune tolerance toward tumor-associated-antigens enables growth of human hepatoma in mice. Int. J. Cancer 97: 52-57.
    • (2002) Int. J. Cancer , vol.97 , pp. 52-57
    • Gotsman, I.1    Israeli, D.2    Alper, R.3    Rabbani, E.4    Engelhardt, D.5    Ilan, Y.6
  • 58
    • 0025886953 scopus 로고
    • Adoptive T cell therapy of tumors: Mechanisms operative in the recognition and elimination of tumor cells
    • Greenberg, P. D. 1991. Adoptive T cell therapy of tumors: mechanisms operative in the recognition and elimination of tumor cells. Adv. Immunol. 49: 281-355.
    • (1991) Adv. Immunol. , vol.49 , pp. 281-355
    • Greenberg, P.D.1
  • 60
    • 2442563529 scopus 로고    scopus 로고
    • The ability of two Listeria monocytogenes vaccines targeting human papillomavirus-16 E7 to induce an antitumor response correlates with myeloid dendriitc cell function
    • Peng, X., S. F. Hussain, and Y. Paterson. 2004. The ability of two Listeria monocytogenes vaccines targeting human papillomavirus-16 E7 to induce an antitumor response correlates with myeloid dendriitc cell function. J. Immunol. 172: 6030-6038.
    • (2004) J. Immunol. , vol.172 , pp. 6030-6038
    • Peng, X.1    Hussain, S.F.2    Paterson, Y.3
  • 61
    • 2942559009 scopus 로고    scopus 로고
    • Cancer immunotherapy with mRNA-transfected dendritic cells
    • Gilboa, E., and J. Vieweg. 2004. Cancer immunotherapy with mRNA-transfected dendritic cells. Immunol. Rev. 199: 251-263.
    • (2004) Immunol. Rev. , vol.199 , pp. 251-263
    • Gilboa, E.1    Vieweg, J.2
  • 64
    • 0038744609 scopus 로고    scopus 로고
    • Dendritic cells transduced with TAT protein transduction domain-containing tyrosinase-related protein 2 vaccinate against murine melanoma
    • Shibagaki, N., and M. C. Udey. 2003. Dendritic cells transduced with TAT protein transduction domain-containing tyrosinase-related protein 2 vaccinate against murine melanoma. Eur. J. Immunol. 33: 850-860.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 850-860
    • Shibagaki, N.1    Udey, M.C.2
  • 65
    • 85044706059 scopus 로고    scopus 로고
    • Induction of autoantibodies against tyrosinase-related proteins following DNA vaccination: Unexpected reactivity to a protein paralogue
    • Srinivasan, R., A. N. Houghton, and J. D. Wolchok. 2002. Induction of autoantibodies against tyrosinase-related proteins following DNA vaccination: unexpected reactivity to a protein paralogue. Cancer Immun. 2: 8.
    • (2002) Cancer Immun. , vol.2 , pp. 8
    • Srinivasan, R.1    Houghton, A.N.2    Wolchok, J.D.3
  • 66
    • 0035113524 scopus 로고    scopus 로고
    • Therapeutic tumor immunity induced by polyimmunization with melanoma antigens gp100 and TRP-2
    • Mendiratta, S. K., G. Thai, N. K. Eslahi, N. M. Thull, M. Matar, V. Bronte, and F. Pericle. 2001. Therapeutic tumor immunity induced by polyimmunization with melanoma antigens gp100 and TRP-2. Cancer Res. 61: 859-863.
    • (2001) Cancer Res. , vol.61 , pp. 859-863
    • Mendiratta, S.K.1    Thai, G.2    Eslahi, N.K.3    Thull, N.M.4    Matar, M.5    Bronte, V.6    Pericle, F.7
  • 68
    • 0036098003 scopus 로고    scopus 로고
    • Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity
    • Knutson, K. L., K. Schiffman, M. A. Cheever, and M. L. Disis. 2002. Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity. Clin. Cancer Res. 8: 1014-1018.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 1014-1018
    • Knutson, K.L.1    Schiffman, K.2    Cheever, M.A.3    Disis, M.L.4
  • 70
    • 0033485764 scopus 로고    scopus 로고
    • Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression
    • Lee, K. H., E. Wang, M. B. Nielsen, J. Wunderlich, S. Migueles, M. Connors, S. M. Steinberg, S. A. Rosenberg, and F. M. Marincola. 1999. Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression. J. Immunol. 163: 6292-6300.
    • (1999) J. Immunol. , vol.163 , pp. 6292-6300
    • Lee, K.H.1    Wang, E.2    Nielsen, M.B.3    Wunderlich, J.4    Migueles, S.5    Connors, M.6    Steinberg, S.M.7    Rosenberg, S.A.8    Marincola, F.M.9
  • 71
    • 0033405438 scopus 로고    scopus 로고
    • Vaccination with Mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma
    • Thurner, B., I. Haendle, C. Rôder, D. Dieckmann, P. Keikavoussi, H. Jonuleit, A. Bender, C. Maczek, D. Schreiner, P. von den Driesch, et al. 1999. Vaccination with Mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J. Exp. Med. 190: 1669-1678.
    • (1999) J. Exp. Med. , vol.190 , pp. 1669-1678
    • Thurner, B.1    Haendle, I.2    Rôder, C.3    Dieckmann, D.4    Keikavoussi, P.5    Jonuleit, H.6    Bender, A.7    Maczek, C.8    Schreiner, D.9    Von Den Driesch, P.10
  • 74
    • 0034735552 scopus 로고    scopus 로고
    • The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments
    • Mahnke, K., M. Guo, S. Lee, H. Sepulveda, S. L. Swain, M. Nussenzweig, and R. M. Steinman. 2000. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J. Cell Biol. 151: 673-683.
    • (2000) J. Cell Biol. , vol.151 , pp. 673-683
    • Mahnke, K.1    Guo, M.2    Lee, S.3    Sepulveda, H.4    Swain, S.L.5    Nussenzweig, M.6    Steinman, R.M.7
  • 77
    • 0142157136 scopus 로고    scopus 로고
    • Human telomerase reverse transcriptase-specific T-helper responses induced by promiscuous major histocompatibility complex class II-restricted epitopes
    • Schroers, R., L. Shen, L. Rollins, C. M. Rooney, K. Slawin, G. Sonderstrup, X. F. Huang, and S. Y. Chen. 2003. Human telomerase reverse transcriptase-specific T-helper responses induced by promiscuous major histocompatibility complex class II-restricted epitopes. Clin. Cancer Res. 9: 4743-4755.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 4743-4755
    • Schroers, R.1    Shen, L.2    Rollins, L.3    Rooney, C.M.4    Slawin, K.5    Sonderstrup, G.6    Huang, X.F.7    Chen, S.Y.8
  • 79
    • 0037221289 scopus 로고    scopus 로고
    • Ablation of CD8 and CD4 T cell responses by high viral loads
    • Fuller, M. J., and A. J. Zajac. 2003. Ablation of CD8 and CD4 T cell responses by high viral loads. J. Immunol. 170: 477-486.
    • (2003) J. Immunol. , vol.170 , pp. 477-486
    • Fuller, M.J.1    Zajac, A.J.2
  • 80
    • 0035808786 scopus 로고    scopus 로고
    • + T cell responses during chronic virus infection prevents neutralizing antibody responses against virus escape mutants
    • + T cell responses during chronic virus infection prevents neutralizing antibody responses against virus escape mutants. J. Exp. Med. 193: 297-306.
    • (2001) J. Exp. Med. , vol.193 , pp. 297-306
    • Ciurea, A.1    Hunziker, L.2    Klenerman, P.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 87
    • 0025147364 scopus 로고
    • Evidence of a role for TNF-anti- in cytolysis by CD4+, class II MHC-restricted cytotoxic T cells
    • Tite, J. P. 1990. Evidence of a role for TNF-anti- in cytolysis by CD4+, class II MHC-restricted cytotoxic T cells. Immunol. 71: 208-212.
    • (1990) Immunol. , vol.71 , pp. 208-212
    • Tite, J.P.1
  • 89
    • 12544259115 scopus 로고    scopus 로고
    • A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication
    • Xiang, R., N. Mizutani, Y. Luo, C. Chiodoni, H. Zhou, M. Mizutani, Y. Ba, J. C. Becker, and R. A. Reisfeld. 2005. A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication. Cancer Res. 65: 553-561.
    • (2005) Cancer Res. , vol.65 , pp. 553-561
    • Xiang, R.1    Mizutani, N.2    Luo, Y.3    Chiodoni, C.4    Zhou, H.5    Mizutani, M.6    Ba, Y.7    Becker, J.C.8    Reisfeld, R.A.9


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