Differential antigen processing by dendritic cell subsets in vivo

Science

Volumn 315, Issue 5808, 2007, Pages 107-111

  Dudziak, Diana ^a   Kamphorst, Alice O ^a   Heidkamp, Gordon F ^a   Buchholz, Veit R ^a   Trumpfheller, Christine ^a   Yamazaki, Sayuri ^a   Cheong, Cheolho ^a   Liu, Kang ^a   Lee, Han Woong ^b   Chae, Gyu Park ^a   Steinman, Ralph M ^a   Nussenzweig, Michel C ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Yonsei University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD205 ANTIGEN; CD8 ANTIGEN; LECTIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; UNCLASSIFIED DRUG;

ANTIBODY; ANTIGEN; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNITY; MAJOR HISTOCOMPATIBILITY COMPLEX; PROTEIN;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DENDRITIC CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN PRESENTATION; ANTIGENS, CD; ANTIGENS, CD8; BASE SEQUENCE; DENDRITIC CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, CELL SURFACE; T-LYMPHOCYTES;

EID: 33846636409     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1136080     Document Type: Article

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29. We thank K. Velinzon for cell sorting; K.-H. Yao for technical assistance; H.-K. Lee, S. H. Park, and S. Y. Joe for help generating CD11c-hDEC205 mice; A. Flores-Langarica, S. Boscardin, A. Gazumyan, E. Besmer, and F. Nimmerjahn for helpful discussion; the MSKCC Monoclonal Antibody Core Facility for labeling of antibodies; and MSKCC Genomics Core Laboratory for performing the microarrays. Supported by grants from the NIH (to C.G.P., R.M.S., and M.C.N.). D.D. is a fellow of the Deutsche Forschungsgemeinschaft (DU 548/1-1), and V.R.B. was supported by the German National Academic Foundation. M.C.N. is an Investigator with the Howard Hughes Medical Institute. M.C.N. and R.M.S. are on the scientific advisory board of Celldex, a startup company interested in targeting dendritic cells.