Targeting of LcrV virulence protein from Yersinia pestis to dendritic cells protects mice against pneumonic plague

European Journal of Immunology

Volumn 40, Issue 10, 2010, Pages 2791-2796

  Do, Yoonkyung ^a,b   Koh, Hyein ^a   Park, Chae Gyu ^a   Dudziak, Diana ^c   Seo, Patrick ^a   Mehandru, S ^a   Choi, Jae Hoon ^a   Cheong, Cheolho ^a   Park, Steven ^d   Perlin, David S ^d   Powell, Bradford S ^e   Steinman, Ralph M ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Ulsan National Institute of Science and Technology   (South Korea)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^d PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

^e UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

CD205 DEC 205; DC; DCIR2; LcrV; Yersinia pestis

Indexed keywords

ALUMINUM HYDROXIDE; BACTERIAL PROTEIN; CD8ALPHA ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; LYMPHOCYTE ANTIGEN; MONOCLONAL ANTIBODY; PROTEIN DCIR2; PROTEIN DEC 205; PROTEIN LCRV; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; BACTERIAL VIRULENCE; CD4+ T LYMPHOCYTE; CELL SECRETION; CELLULAR IMMUNITY; COMPARATIVE STUDY; CONTROLLED STUDY; DENDRITIC CELL; EVALUATION; HUMORAL IMMUNITY; IMMUNE RESPONSE; MOUSE; NONHUMAN; PLAGUE; PRIORITY JOURNAL; TH1 CELL; TH2 CELL; VACCINATION; VIRULENCE; YERSINIA PESTIS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; CYTOKINES; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNIZATION; MICE; MICE, INBRED BALB C; PLAGUE; PLAGUE VACCINE; PORE FORMING CYTOTOXIC PROTEINS; SPECIFIC PATHOGEN-FREE ORGANISMS; SURVIVAL ANALYSIS; VACCINES, SYNTHETIC; VIRULENCE; YERSINIA PESTIS;

EID: 77957131592     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040511     Document Type: Article

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