Dendritic cell-targeted pancreatic β-cell antigen leads to conversion of self-reactive CD4+ T cells into regulatory T cells and promotes immunotolerance in NOD mice

Review of Diabetic Studies

Volumn 7, Issue 1, 2010, Pages 45-55

  Petzold, Cathleen ^a   Riewaldt, Julia ^a   Koenig, Tina ^a   Schallenberg, Sonja ^a   Kretschmer, Karsten ^a  

^a CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

Author keywords

Autoimmunity; BDC2.5 mimotope; DEC 205; Dendritic cell; FoxP3; Immune regulation; NOD mouse; Proinsulin; Regulatory T cell; Type 1 diabetes

Indexed keywords

CD205 ANTIBODY; CELL ANTIBODY; PROINSULIN; T LYMPHOCYTE ANTIGEN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; ANTIBODY; AUTOANTIGEN; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL TRANSFORMATION; CONTROLLED STUDY; DENDRITIC CELL; DISEASE COURSE; GENE EXPRESSION REGULATION; HYPERGLYCEMIA; IMMUNOLOGICAL TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; INCIDENCE; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; PROTEIN TARGETING; REGULATORY T LYMPHOCYTE; ANIMAL; FEMALE; GENETICS; IMMUNOLOGY; MALE;

ANIMALS; ANTIBODIES; AUTOANTIGENS; AUTOIMMUNITY; CD4-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 1; FEMALE; IMMUNE TOLERANCE; INSULIN-SECRETING CELLS; MALE; MICE; MICE, INBRED NOD; RECOMBINANT PROTEINS;

EID: 79952116856     PISSN: 16136071     EISSN: 16140575     Source Type: Journal    
DOI: 10.1900/RDS.2010.7.45     Document Type: Article

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