-
1
-
-
54849437711
-
Review of clinical studies on dendritic cell-based vaccination of patients with malignant melanoma: Assessment of correlation between clinical response and vaccine parameters
-
Overview of dendritic cell (DC) vaccines in melanoma patients, demonstrating both the achievable clinical efficacy and the variability in outcome of vaccination
-
Engell-Noerregaard L, Hansen TH, Andersen MH, Thor Straten P, Svane IM: Review of clinical studies on dendritic cell-based vaccination of patients with malignant melanoma: assessment of correlation between clinical response and vaccine parameters. Cancer Immunol. Immunother. 58, 1-14 (2009). Overview of dendritic cell (DC) vaccines in melanoma patients, demonstrating both the achievable clinical efficacy and the variability in outcome of vaccination.
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 1-14
-
-
Engell-Noerregaard, L.1
Hansen, T.H.2
Andersen, M.H.3
Thor Straten, P.4
Svane, I.M.5
-
5
-
-
77953265082
-
Dendritic cell preparation for immunotherapeutic interventions
-
Simon T, Fonteneau JF, Gregoire M: Dendritic cell preparation for immunotherapeutic interventions. Immunotherapy 1, 289-302 (2009).
-
(2009)
Immunotherapy
, vol.1
, pp. 289-302
-
-
Simon, T.1
Fonteneau, J.F.2
Gregoire, M.3
-
7
-
-
67349239049
-
T-regulatory cell modulation: The future of cancer immunotherapy?
-
Nizar S, Copier J, Meyer B et al.: T-regulatory cell modulation: the future of cancer immunotherapy? Br. J. Cancer 100, 1697-1703 (2009).
-
(2009)
Br. J. Cancer
, vol.100
, pp. 1697-1703
-
-
Nizar, S.1
Copier, J.2
Meyer, B.3
-
8
-
-
77958056009
-
Dendritic cell vaccination in combination with anti-CD25 monoclonal antibody treatment: A Phase I/II study in metastatic melanoma patients
-
Jacobs JF, Punt CJ, Lesterhuis WJ et al.: Dendritic cell vaccination in combination with anti-CD25 monoclonal antibody treatment: a Phase I/II study in metastatic melanoma patients. Clin. Cancer Res. 16, 5067-5078 (2010).
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 5067-5078
-
-
Jacobs, J.F.1
Punt, C.J.2
Lesterhuis, W.J.3
-
9
-
-
33847368549
-
+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
-
+ regulatory T cells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol. Immunother. 56, 641-648 (2007).
-
(2007)
Cancer Immunol. Immunother.
, vol.56
, pp. 641-648
-
-
Ghiringhelli, F.1
Menard, C.2
Puig, P.E.3
-
10
-
-
74349102406
-
Administration of cyclophosphamide changes the immune profile of tumor-bearing mice
-
Liu P, Jaffar J, Hellstrom I, Hellstrom KE: Administration of cyclophosphamide changes the immune profile of tumor-bearing mice. J. Immunother. 33, 53-59 (2010).
-
(2010)
J. Immunother.
, vol.33
, pp. 53-59
-
-
Liu, P.1
Jaffar, J.2
Hellstrom, I.3
Hellstrom, K.E.4
-
11
-
-
70249083099
-
What is the role of cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma?
-
Robert C, Ghiringhelli F: What is the role of cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma? Oncologist 14, 848-861 (2009).
-
(2009)
Oncologist
, vol.14
, pp. 848-861
-
-
Robert, C.1
Ghiringhelli, F.2
-
12
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF et al.: Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363, 711-723 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
13
-
-
77951637543
-
Blockade of programmed death ligand 1 enhances the therapeutic efficacy of combination immunotherapy against melanoma
-
Pilon-Thomas S, Mackay A, Vohra N, Mule JJ: Blockade of programmed death ligand 1 enhances the therapeutic efficacy of combination immunotherapy against melanoma. J. Immunol. 184, 3442-3449 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 3442-3449
-
-
Pilon-Thomas, S.1
Mackay, A.2
Vohra, N.3
Mule, J.J.4
-
14
-
-
77949718839
-
Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer
-
Nagaraj S, Youn JI, Weber H et al.: Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer. Clin. Cancer Res. 16, 1812-1823 (2010).
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 1812-1823
-
-
Nagaraj, S.1
Youn, J.I.2
Weber, H.3
-
15
-
-
74249120625
-
Pre-treatment with chemotherapy can enhance the antigenicity and immunogenicity of tumours by promoting adaptive immune responses
-
Liu WM, Fowler DW, Smith P, Dalgleish AG: Pre-treatment with chemotherapy can enhance the antigenicity and immunogenicity of tumours by promoting adaptive immune responses. Br. J. Cancer 102, 115-123 (2010).
-
(2010)
Br. J. Cancer
, vol.102
, pp. 115-123
-
-
Liu, W.M.1
Fowler, D.W.2
Smith, P.3
Dalgleish, A.G.4
-
16
-
-
43149098068
-
Anti-inflammatory pretreatment enables an efficient dendritic cell-based immunotherapy against established tumors
-
Chiarella P, Vulcano M, Bruzzo J et al.: Anti-inflammatory pretreatment enables an efficient dendritic cell-based immunotherapy against established tumors. Cancer Immunol. Immunother. 57, 701-718 (2008).
-
(2008)
Cancer Immunol. Immunother.
, vol.57
, pp. 701-718
-
-
Chiarella, P.1
Vulcano, M.2
Bruzzo, J.3
-
17
-
-
70349100093
-
Massive expansion of regulatory T-cells following interleukin 2 treatment during a Phase I-II dendritic cell-based immunotherapy of metastatic renal cancer
-
Lemoine FM, Cherai M, Giverne C et al.: Massive expansion of regulatory T-cells following interleukin 2 treatment during a Phase I-II dendritic cell-based immunotherapy of metastatic renal cancer. Int. J. Oncol. 35, 569-581 (2009).
-
(2009)
Int. J. Oncol.
, vol.35
, pp. 569-581
-
-
Lemoine, F.M.1
Cherai, M.2
Giverne, C.3
-
18
-
-
68049140780
-
Clinical and immunologic effects of intranodal autologous tumor lysate-dendritic cell vaccine with Aldesleukin (interleukin 2) and IFN-a2a therapy in metastatic renal cell carcinoma patients
-
Schwaab T, Schwarzer A, Wolf B et al.: Clinical and immunologic effects of intranodal autologous tumor lysate-dendritic cell vaccine with Aldesleukin (interleukin 2) and IFN-a2a therapy in metastatic renal cell carcinoma patients. Clin. Cancer Res. 15, 4986-4992 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 4986-4992
-
-
Schwaab, T.1
Schwarzer, A.2
Wolf, B.3
-
19
-
-
48649102654
-
Alterations in p53-specific T cells and other lymphocyte subsets in breast cancer patients during vaccination with p53-peptide loaded dendritic cells and low-dose interleukin-2
-
Svane IM, Pedersen AE, Nikolajsen K, Zocca MB: Alterations in p53-specific T cells and other lymphocyte subsets in breast cancer patients during vaccination with p53-peptide loaded dendritic cells and low-dose interleukin-2. Vaccine 26, 4716-4724 (2008).
-
(2008)
Vaccine
, vol.26
, pp. 4716-4724
-
-
Svane, I.M.1
Pedersen, A.E.2
Nikolajsen, K.3
Zocca, M.B.4
-
20
-
-
77957319524
-
Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: Results from a Phase I/II trial
-
Trepiakas R, Berntsen A, Hadrup SR et al.: Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: results from a Phase I/II trial. Cytotherapy 12, 721-734 (2010).
-
(2010)
Cytotherapy
, vol.12
, pp. 721-734
-
-
Trepiakas, R.1
Berntsen, A.2
Hadrup, S.R.3
-
21
-
-
68549135290
-
Integrated data from 2 randomized, double-blind, placebo-controlled, Phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
-
Higano CS, Schellhammer PF, Small EJ et al.: Integrated data from 2 randomized, double-blind, placebo-controlled, Phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 115, 3670-3679 (2009).
-
(2009)
Cancer
, vol.115
, pp. 3670-3679
-
-
Higano, C.S.1
Schellhammer, P.F.2
Small, E.J.3
-
22
-
-
66549098937
-
Improving the efficacy of cancer immunotherapy
-
Copier J, Dalgleish AG, Britten CM et al.: Improving the efficacy of cancer immunotherapy. Eur. J. Cancer 45, 1424-1431 (2009).
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 1424-1431
-
-
Copier, J.1
Dalgleish, A.G.2
Britten, C.M.3
-
23
-
-
33845993628
-
A clinical development paradigm for cancer vaccines and related biologics
-
Hoos A, Parmiani G, Hege K et al.: A clinical development paradigm for cancer vaccines and related biologics. J. Immunother. 30, 1-15 (2007).
-
(2007)
J. Immunother.
, vol.30
, pp. 1-15
-
-
Hoos, A.1
Parmiani, G.2
Hege, K.3
-
24
-
-
65249173447
-
Adoptive cell therapy for the treatment of patients with metastatic melanoma
-
Rosenberg SA, Dudley ME: Adoptive cell therapy for the treatment of patients with metastatic melanoma. Curr. Opin. Immunol. 21, 233-240 (2009).
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 233-240
-
-
Rosenberg, S.A.1
Dudley, M.E.2
-
25
-
-
0037174674
-
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
-
Dudley ME, Wunderlich JR, Robbins PF et al.: Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 298, 850-854 (2002).
-
(2002)
Science
, vol.298
, pp. 850-854
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Robbins, P.F.3
-
26
-
-
77958064837
-
Tumor infiltrating lymphocyte therapy for metastatic melanoma: Analysis of tumors resected for TIL
-
Data from Phase III clinical trials of sipuleucel-T, an autologous DC vaccine, which has recently been awarded a licence in the USA for the treatment of advanced prostate cancer
-
Goff SL, Smith FO, Klapper JA et al.: Tumor infiltrating lymphocyte therapy for metastatic melanoma: analysis of tumors resected for TIL. J. Immunother. 33, 840-847 (2010). Data from Phase III clinical trials of sipuleucel-T, an autologous DC vaccine, which has recently been awarded a licence in the USA for the treatment of advanced prostate cancer.
-
(2010)
J. Immunother.
, vol.33
, pp. 840-847
-
-
Goff, S.L.1
Smith, F.O.2
Klapper, J.A.3
-
28
-
-
0037829421
-
Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients
-
Dudley ME, Wunderlich JR, Shelton TE, Even J, Rosenberg SA: Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J. Immunother. 26, 332-342 (2003).
-
(2003)
J. Immunother.
, vol.26
, pp. 332-342
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Shelton, T.E.3
Even, J.4
Rosenberg, S.A.5
-
29
-
-
12744253307
-
Sinks, suppressors and antigen presenters: How lymphodepletion enhances T cell-mediated tumor immunotherapy
-
Klebanoff CA, Khong HT, Antony PA, Palmer DC, Restifo NP: Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy. Trends Immunol. 26, 111-117 (2005).
-
(2005)
Trends Immunol.
, vol.26
, pp. 111-117
-
-
Klebanoff, C.A.1
Khong, H.T.2
Antony, P.A.3
Palmer, D.C.4
Restifo, N.P.5
-
30
-
-
73349118752
-
Dendritic cell recovery post-lymphodepletion: A potential mechanism for anti-cancer adoptive T cell therapy and vaccination
-
Original study in melanoma patients showing that tumor-derived T cells could produce both clinical and immunological effects
-
Salem ML, Cole DJ: Dendritic cell recovery post-lymphodepletion: a potential mechanism for anti-cancer adoptive T cell therapy and vaccination. Cancer Immunol. Immunother. 59, 341-353 (2010). Original study in melanoma patients showing that tumor-derived T cells could produce both clinical and immunological effects.
-
(2010)
Cancer Immunol. Immunother.
, vol.59
, pp. 341-353
-
-
Salem, M.L.1
Cole, D.J.2
-
31
-
-
20244366111
-
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
-
Dudley ME, Wunderlich JR, Yang JC et al.: Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J. Clin. Oncol. 23, 2346-2357 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 2346-2357
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Yang, J.C.3
-
32
-
-
74349084455
-
Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells
-
Wrzesinski C, Paulos CM, Kaiser A et al.: Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells. J. Immunother. 33, 1-7 (2010).
-
(2010)
J. Immunother.
, vol.33
, pp. 1-7
-
-
Wrzesinski, C.1
Paulos, C.M.2
Kaiser, A.3
-
33
-
-
55949125601
-
Adoptive cell therapy for patients with metastatic melanoma: Evaluation of intensive myeloablative chemoradiation preparative regimens
-
Dudley ME, Yang JC, Sherry R et al.: Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. J. Clin. Oncol. 26, 5233-5239 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 5233-5239
-
-
Dudley, M.E.1
Yang, J.C.2
Sherry, R.3
-
34
-
-
62749185585
-
Fludarabine modulates immune response and extends in vivo survival of adoptively transferred CD8 T cells in patients with metastatic melanoma
-
Wallen H, Thompson JA, Reilly JZ et al.: Fludarabine modulates immune response and extends in vivo survival of adoptively transferred CD8 T cells in patients with metastatic melanoma. PLoS One 4, E4749 (2009).
-
(2009)
PLoS One
, vol.4
-
-
Wallen, H.1
Thompson, J.A.2
Reilly, J.Z.3
-
36
-
-
38149117105
-
+ T cells derived from central memory cells establishes persistent T cell memory in primates
-
+ T cells derived from central memory cells establishes persistent T cell memory in primates. J. Clin. Invest. 118, 294-305 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 294-305
-
-
Berger, C.1
Jensen, M.C.2
Lansdorp, P.M.3
-
37
-
-
34249819361
-
Detection and long-term in vivo monitoring of individual tumor-specific T cell clones in patients with metastatic melanoma
-
Michalek J, Kocak I, Fait V, Zaloudik J, Hajek R: Detection and long-term in vivo monitoring of individual tumor-specific T cell clones in patients with metastatic melanoma. J. Immunol. 178, 6789-6795 (2007).
-
(2007)
J. Immunol.
, vol.178
, pp. 6789-6795
-
-
Michalek, J.1
Kocak, I.2
Fait, V.3
Zaloudik, J.4
Hajek, R.5
-
38
-
-
70149114880
-
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
-
Differences in clinical outcome achievable through alteration of host environment prior to adoptive therapy. This was related to intensity of lymphodepletion
-
Johnson LA, Morgan RA, Dudley ME et al.: Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood 114, 535-546 (2009). Differences in clinical outcome achievable through alteration of host environment prior to adoptive therapy. This was related to intensity of lymphodepletion.
-
(2009)
Blood
, vol.114
, pp. 535-546
-
-
Johnson, L.A.1
Morgan, R.A.2
Dudley, M.E.3
-
40
-
-
77957305114
-
The interplay between Epstein-Barr virus and the immune system: A rationale for adoptive cell therapy of EBV-related disorders
-
Merlo A, Turrini R, Dolcetti R et al.: The interplay between Epstein-Barr virus and the immune system: a rationale for adoptive cell therapy of EBV-related disorders. Haematologica 95, 1769-1777 (2010).
-
(2010)
Haematologica
, vol.95
, pp. 1769-1777
-
-
Merlo, A.1
Turrini, R.2
Dolcetti, R.3
-
41
-
-
77958014713
-
Adoptive therapy using antigen-specific T-cell clones
-
Yee C: Adoptive therapy using antigen-specific T-cell clones. Cancer J. 16, 367-373 (2010).
-
(2010)
Cancer J.
, vol.16
, pp. 367-373
-
-
Yee, C.1
-
42
-
-
79959351392
-
Treatment of metastatic melanoma with autologous Melan-A/MART-1-specific cytotoxic T lymphocyte clones
-
Khammari A, Labarriere N, Vignard V et al.: Treatment of metastatic melanoma with autologous Melan-A/MART-1-specific cytotoxic T lymphocyte clones. J. Invest. Dermatol. 129, 2835-2842 (2009).
-
(2009)
J. Invest. Dermatol.
, vol.129
, pp. 2835-2842
-
-
Khammari, A.1
Labarriere, N.2
Vignard, V.3
-
43
-
-
77951257237
-
Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens
-
Warren EH, Fujii N, Akatsuka Y et al.: Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens. Blood 115, 3869-3878 (2010).
-
(2010)
Blood
, vol.115
, pp. 3869-3878
-
-
Warren, E.H.1
Fujii, N.2
Akatsuka, Y.3
-
44
-
-
77953457564
-
Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase
-
Frankel TL, Burns WR, Peng PD et al.: Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase. J. Immunol. 184, 5988-5998 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 5988-5998
-
-
Frankel, T.L.1
Burns, W.R.2
Peng, P.D.3
-
45
-
-
77955270629
-
+ T cells exhibit multifunctional effector and helper responses, in vitro
-
+ T cells exhibit multifunctional effector and helper responses, in vitro. Clin. Immunol. 136, 338-347 (2010).
-
(2010)
Clin. Immunol.
, vol.136
, pp. 338-347
-
-
Ray, S.1
Chhabra, A.2
Chakraborty, N.G.3
-
46
-
-
77956535599
-
Redirecting T-cell specificity by introducing a tumorspecific chimeric antigen receptor
-
Jena B, Dotti G, Cooper LJ: Redirecting T-cell specificity by introducing a tumorspecific chimeric antigen receptor. Blood 116, 1035-1044 (2010).
-
(2010)
Blood
, vol.116
, pp. 1035-1044
-
-
Jena, B.1
Dotti, G.2
Cooper, L.J.3
-
47
-
-
77951089216
-
A high molecular weight melanoma-associated antigen-specific chimeric antigen receptor redirects lymphocytes to target human melanomas
-
Burns WR, Zhao Y, Frankel TL et al.: A high molecular weight melanoma-associated antigen-specific chimeric antigen receptor redirects lymphocytes to target human melanomas. Cancer Res. 70, 3027-3033 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 3027-3033
-
-
Burns, W.R.1
Zhao, Y.2
Frankel, T.L.3
-
48
-
-
77950475517
-
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
-
Morgan RA, Yang JC, Kitano M et al.: Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol. Ther. 18, 843-851 (2010).
-
(2010)
Mol. Ther.
, vol.18
, pp. 843-851
-
-
Morgan, R.A.1
Yang, J.C.2
Kitano, M.3
-
49
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
Morgan RA, Dudley ME, Wunderlich JR et al.: Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 314, 126-129 (2006).
-
(2006)
Science
, vol.314
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
-
50
-
-
42649085033
-
Nonmyeloablative chemotherapy followed by T-cell adoptive transfer and dendritic cell-based vaccination results in rejection of established melanoma
-
Along with references [51] and [52] demonstrates the potential synergy between DC vaccination and T-cell therapy
-
Koike N, Pilon-Thomas S, Mule JJ: Nonmyeloablative chemotherapy followed by T-cell adoptive transfer and dendritic cell-based vaccination results in rejection of established melanoma. J. Immunother. 31, 402-412 (2008). Along with references [51] and [52] demonstrates the potential synergy between DC vaccination and T-cell therapy.
-
(2008)
J. Immunother.
, vol.31
, pp. 402-412
-
-
Koike, N.1
Pilon-Thomas, S.2
Mule, J.J.3
-
51
-
-
4644364500
-
Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo
-
Along with references [50] and [52] demonstrates the potential synergy between DC vaccination and T-cell therapy
-
Lou Y, Wang G, Lizee G et al.: Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo. Cancer Res. 64, 6783-6790 (2004). Along with references [50] and [52] demonstrates the potential synergy between DC vaccination and T-cell therapy.
-
(2004)
Cancer Res.
, vol.64
, pp. 6783-6790
-
-
Lou, Y.1
Wang, G.2
Lizee, G.3
-
52
-
-
77956500311
-
+ T cell/regulatory T cells in tumour
-
Along with references [50] and [51] demonstrates the potential synergy between DC vaccination and T-cell therapy
-
+ T cell/regulatory T cells in tumour. Clin. Exp. Immunol. 162, 75-83 (2010). Along with references [50] and [51] demonstrates the potential synergy between DC vaccination and T-cell therapy.
-
(2010)
Clin. Exp. Immunol.
, vol.162
, pp. 75-83
-
-
Song, S.1
Zhang, K.2
You, H.3
-
53
-
-
40549097760
-
Adoptive immunotherapy for pancreatic cancer using MUC1 peptide-pulsed dendritic cells and activated T lymphocytes
-
Kondo H, Hazama S, Kawaoka T et al.: Adoptive immunotherapy for pancreatic cancer using MUC1 peptide-pulsed dendritic cells and activated T lymphocytes. Anticancer Res. 28, 379-387 (2008).
-
(2008)
Anticancer Res.
, vol.28
, pp. 379-387
-
-
Kondo, H.1
Hazama, S.2
Kawaoka, T.3
-
54
-
-
33846813974
-
Safety profile and anti-tumor effects of adoptive immunotherapy using γ-δ T cells against advanced renal cell carcinoma: A pilot study
-
Kobayashi H, Tanaka Y, Yagi J et al.: Safety profile and anti-tumor effects of adoptive immunotherapy using γ-δ T cells against advanced renal cell carcinoma: a pilot study. Cancer Immunol. Immunother. 56, 469-476 (2007).
-
(2007)
Cancer Immunol. Immunother.
, vol.56
, pp. 469-476
-
-
Kobayashi, H.1
Tanaka, Y.2
Yagi, J.3
-
55
-
-
50649102839
-
Phase-I study of Innacell γδ, an autologous cell-therapy product highly enriched in γ9δ2 T lymphocytes, in combination with IL-2, in patients with metastatic renal cell carcinoma
-
Bennouna J, Bompas E, Neidhardt EM et al.: Phase-I study of Innacell γδ, an autologous cell-therapy product highly enriched in γ9δ2 T lymphocytes, in combination with IL-2, in patients with metastatic renal cell carcinoma. Cancer Immunol. Immunother. 57, 1599-1609 (2008).
-
(2008)
Cancer Immunol. Immunother.
, vol.57
, pp. 1599-1609
-
-
Bennouna, J.1
Bompas, E.2
Neidhardt, E.M.3
-
56
-
-
77951296062
-
A Phase I study of adoptive immunotherapy for recurrent non-small-cell lung cancer patients with autologous γδ T cells
-
Nakajima J, Murakawa T, Fukami T et al.: A Phase I study of adoptive immunotherapy for recurrent non-small-cell lung cancer patients with autologous γδ T cells. Eur. J. Cardiothorac. Surg. 37, 1191-1197 (2010).
-
(2010)
Eur. J. Cardiothorac. Surg.
, vol.37
, pp. 1191-1197
-
-
Nakajima, J.1
Murakawa, T.2
Fukami, T.3
-
57
-
-
78650386896
-
Zoledronate-activated Vγ9γδ T cell-based immunotherapy is feasible and restores the impairment of γδ T cells in patients with solid tumors
-
Noguchi A, Kaneko T, Kamigaki T et al.: Zoledronate-activated Vγ9γδ T cell-based immunotherapy is feasible and restores the impairment of γδ T cells in patients with solid tumors. Cytotherapy 13(1), 92-97 (2010).
-
(2010)
Cytotherapy
, vol.13
, Issue.1
, pp. 92-97
-
-
Noguchi, A.1
Kaneko, T.2
Kamigaki, T.3
-
58
-
-
0037968274
-
γδ T cells for immune therapy of patients with lymphoid malignancies
-
Wilhelm M, Kunzmann V, Eckstein S et al.: γδ T cells for immune therapy of patients with lymphoid malignancies. Blood 102, 200-206 (2003).
-
(2003)
Blood
, vol.102
, pp. 200-206
-
-
Wilhelm, M.1
Kunzmann, V.2
Eckstein, S.3
-
59
-
-
34547638252
-
Targeting human γδ T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer
-
Analysis of peripheral γδ T-cell activation and phenotype in patients treated with aminobisphosphonates. Demonstrates that it is possible to manipulate γδ T cells without the need for ex vivo culture
-
Dieli F, Vermijlen D, Fulfaro F et al.: Targeting human γδ T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer. Cancer Res. 67, 7450-7457 (2007). Analysis of peripheral γδ T-cell activation and phenotype in patients treated with aminobisphosphonates. Demonstrates that it is possible to manipulate γδ T cells without the need for ex vivo culture.
-
(2007)
Cancer Res.
, vol.67
, pp. 7450-7457
-
-
Dieli, F.1
Vermijlen, D.2
Fulfaro, F.3
-
60
-
-
79953819157
-
Adjuvant ovarian suppression combined with tamoxifen or anastrozole, alone or in combination with zoledronic acid, in premenopausal women with hormomeresponsive, stage I and II breast cancer: First efficacy results from ABCSG-12
-
Presented at
-
Gnant M, Mlineritsch B, Schippinger W et al.: Adjuvant ovarian suppression combined with tamoxifen or anastrozole, alone or in combination with zoledronic acid, in premenopausal women with hormomeresponsive, stage I and II breast cancer: first efficacy results from ABCSG-12. Presented at: ASCO Annual Meeting Chicago, IL, USA 30 May-3 June 2008.
-
ASCO Annual Meeting Chicago, IL, USA 30 May-3 June 2008
-
-
Gnant, M.1
Mlineritsch, B.2
Schippinger, W.3
-
61
-
-
54849441655
-
In vivo effects of zoledronic acid on peripheral γδ T lymphocytes in early breast cancer patients
-
Santini D, Martini F, Fratto ME et al.: In vivo effects of zoledronic acid on peripheral γδ T lymphocytes in early breast cancer patients. Cancer Immunol. Immunother. 58, 31-38 (2009).
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 31-38
-
-
Santini, D.1
Martini, F.2
Fratto, M.E.3
-
62
-
-
77954652637
-
In vivo manipulation of Vγ9Vδ2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients
-
Meraviglia S, Eberl M, Vermijlen D et al.: In vivo manipulation of Vγ9Vδ2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients. Clin. Exp. Immunol. 161, 290-297 (2010).
-
(2010)
Clin. Exp. Immunol.
, vol.161
, pp. 290-297
-
-
Meraviglia, S.1
Eberl, M.2
Vermijlen, D.3
-
63
-
-
67349188865
-
Regression of melanoma metastases following treatment with the N-bisphosphonate zoledronate and localised radiotherapy
-
Laggner U, Lopez JS, Perera G et al.: Regression of melanoma metastases following treatment with the N-bisphosphonate zoledronate and localised radiotherapy. Clin. Immunol. 131, 367-373 (2009).
-
(2009)
Clin. Immunol.
, vol.131
, pp. 367-373
-
-
Laggner, U.1
Lopez, J.S.2
Perera, G.3
-
64
-
-
77957958698
-
The potential of immunomodulatory drugs in the treatment of solid tumors
-
Dalgleish A, Galustian C: The potential of immunomodulatory drugs in the treatment of solid tumors. Future Oncol. 6, 1479-1484 (2010).
-
(2010)
Future Oncol.
, vol.6
, pp. 1479-1484
-
-
Dalgleish, A.1
Galustian, C.2
-
65
-
-
67349107194
-
The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells
-
Galustian C, Meyer B, Labarthe MC et al.: The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells. Cancer Immunol. Immunother. 58, 1033-1045 (2009).
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 1033-1045
-
-
Galustian, C.1
Meyer, B.2
Labarthe, M.C.3
-
66
-
-
68749095218
-
Immunotherapy for malignant melanoma - Tracing Ariadne's thread through the labyrinth
-
Grange JM, Krone B, Stanford JL: Immunotherapy for malignant melanoma - tracing Ariadne's thread through the labyrinth. Eur. J. Cancer 45, 2266-2273 (2009).
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 2266-2273
-
-
Grange, J.M.1
Krone, B.2
Stanford, J.L.3
-
67
-
-
38149032470
-
Successful immunotherapy with Mycobacterium vaccae in the treatment of adenocarcinoma of the lung
-
Stanford JL, Stanford CA, O'Brien ME, Grange JM: Successful immunotherapy with Mycobacterium vaccae in the treatment of adenocarcinoma of the lung. Eur. J. Cancer 44, 224-227 (2008).
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 224-227
-
-
Stanford, J.L.1
Stanford, C.A.2
O'Brien, M.E.3
Grange, J.M.4
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