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Volumn 6, Issue MAR, 2015, Pages

Dendritic cell-based vaccine efficacy: Aiming for hot spots

Author keywords

Antitumor T cells; Cancer vaccines; Dendritic cells; Draining lymph nodes; Immunotherapy; Vaccine injection site

Indexed keywords

DENDRITIC CELL VACCINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

EID: 84926629603     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2015.00091     Document Type: Review
Times cited : (51)

References (107)
  • 1
    • 77957787538 scopus 로고    scopus 로고
    • Therapeutic cancer vaccines in prostate cancer: the paradox of improved survival without changes in time to progression
    • Madan RA, Gulley JL, Fojo T, Dahut WL. Therapeutic cancer vaccines in prostate cancer: the paradox of improved survival without changes in time to progression. Oncologist (2010) 15(9):969-75. doi: 10.1634/theoncologist.2010-0129.
    • (2010) Oncologist , vol.15 , Issue.9 , pp. 969-975
    • Madan, R.A.1    Gulley, J.L.2    Fojo, T.3    Dahut, W.L.4
  • 3
    • 77957989419 scopus 로고    scopus 로고
    • Dendritic cells: are they clinically relevant?
    • Palucka K, Ueno H, Roberts L, Fay J, Banchereau J. Dendritic cells: are they clinically relevant? Cancer J (2010) 16(4):318-24. doi:10.1097/PPO.0b013e3181eaca83.
    • (2010) Cancer J , vol.16 , Issue.4 , pp. 318-324
    • Palucka, K.1    Ueno, H.2    Roberts, L.3    Fay, J.4    Banchereau, J.5
  • 4
    • 84880721353 scopus 로고    scopus 로고
    • Dendritic-cell-based therapeutic cancer vaccines
    • Palucka K, Banchereau J. Dendritic-cell-based therapeutic cancer vaccines. Immunity (2013) 39(1):38-48. doi:10.1016/j.immuni.2013.07.004.
    • (2013) Immunity , vol.39 , Issue.1 , pp. 38-48
    • Palucka, K.1    Banchereau, J.2
  • 5
    • 84880706152 scopus 로고    scopus 로고
    • Oncology meets immunology: the cancer-immunity cycle
    • Chen DS, Mellman I. Oncology meets immunology: the cancer-immunity cycle. Immunity (2013) 39(1):1-10. doi:10.1016/j.immuni.2013.07.012.
    • (2013) Immunity , vol.39 , Issue.1 , pp. 1-10
    • Chen, D.S.1    Mellman, I.2
  • 6
    • 84892144534 scopus 로고    scopus 로고
    • Dendritic cells in cancer immunotherapy clinical trials: are we making progress?
    • Butterfield LH. Dendritic cells in cancer immunotherapy clinical trials: are we making progress? Front Immunol (2013) 4:454. doi:10.3389/fimmu.2013.00454.
    • (2013) Front Immunol , vol.4 , pp. 454
    • Butterfield, L.H.1
  • 8
    • 84890598769 scopus 로고    scopus 로고
    • A model of dendritic cell therapy for melanoma
    • Depillis L, Gallegos A, Radunskaya A. A model of dendritic cell therapy for melanoma. Front Oncol (2013) 3:56. doi:10.3389/fonc.2013.00056.
    • (2013) Front Oncol , vol.3 , pp. 56
    • Depillis, L.1    Gallegos, A.2    Radunskaya, A.3
  • 9
    • 79961170539 scopus 로고    scopus 로고
    • Dendritic cells in cancer immunotherapy: vaccines or autologous transplants?
    • Kalinski P, Edington H, Zeh HJ, Okada H, Butterfield LH, Kirkwood JM, et al. Dendritic cells in cancer immunotherapy: vaccines or autologous transplants? Immunol Res (2011) 50(2-3):235-47. doi:10.1007/s12026-011-8224-z.
    • (2011) Immunol Res , vol.50 , Issue.2-3 , pp. 235-247
    • Kalinski, P.1    Edington, H.2    Zeh, H.J.3    Okada, H.4    Butterfield, L.H.5    Kirkwood, J.M.6
  • 10
    • 29144508613 scopus 로고    scopus 로고
    • Dendritic cell dysfunction in cancer: a mechanism for immunosuppression
    • Pinzon-Charry A, Maxwell T, Lopez JA. Dendritic cell dysfunction in cancer: a mechanism for immunosuppression. Immunol Cell Biol (2005) 83(5):451-61. doi:10.1111/j.1440-1711.2005.01371.x.
    • (2005) Immunol Cell Biol , vol.83 , Issue.5 , pp. 451-461
    • Pinzon-Charry, A.1    Maxwell, T.2    Lopez, J.A.3
  • 12
    • 0032948701 scopus 로고    scopus 로고
    • IL-13 can substitute for IL-4 in the generation of dendritic cells for the induction of cytotoxic T lymphocytes and gene therapy
    • Alters SE, Gadea JR, Holm B, Lebkowski J, Philip R. IL-13 can substitute for IL-4 in the generation of dendritic cells for the induction of cytotoxic T lymphocytes and gene therapy. J Immunother (1999) 22(3):229-36. doi:10.1097/00002371-199905000-00005.
    • (1999) J Immunother , vol.22 , Issue.3 , pp. 229-236
    • Alters, S.E.1    Gadea, J.R.2    Holm, B.3    Lebkowski, J.4    Philip, R.5
  • 14
    • 84892426495 scopus 로고    scopus 로고
    • Dendritic cell-based vaccines: shining the spotlight on signal 3
    • Linette GP, Carreno BM. Dendritic cell-based vaccines: shining the spotlight on signal 3. Oncoimmunology (2013) 2(11):e26512. doi:10.4161/onci.26512.
    • (2013) Oncoimmunology , vol.2 , Issue.11
    • Linette, G.P.1    Carreno, B.M.2
  • 15
    • 79952438607 scopus 로고    scopus 로고
    • Harnessing dendritic cells for immunotherapy
    • Delamarre L, Mellman I. Harnessing dendritic cells for immunotherapy. Semin Immunol (2011) 23(1):2-11. doi:10.1016/j.smim.2011.02.001.
    • (2011) Semin Immunol , vol.23 , Issue.1 , pp. 2-11
    • Delamarre, L.1    Mellman, I.2
  • 16
    • 84855961831 scopus 로고    scopus 로고
    • Third generation dendritic cell vaccines for tumor immunotherapy
    • Frankenberger B, Schendel DJ. Third generation dendritic cell vaccines for tumor immunotherapy. Eur J Cell Biol (2012) 91(1):53-8. doi:10.1016/j.ejcb.2011.01.012.
    • (2012) Eur J Cell Biol , vol.91 , Issue.1 , pp. 53-58
    • Frankenberger, B.1    Schendel, D.J.2
  • 17
    • 2642631750 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions
    • Jonuleit H, Kuhn U, Muller G, Steinbrink K, Paragnik L, Schmitt E, et al. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur J Immunol (1997) 27(12):3135-42. doi:10.1002/eji.1830271209.
    • (1997) Eur J Immunol , vol.27 , Issue.12 , pp. 3135-3142
    • Jonuleit, H.1    Kuhn, U.2    Muller, G.3    Steinbrink, K.4    Paragnik, L.5    Schmitt, E.6
  • 18
    • 50649089811 scopus 로고    scopus 로고
    • Maturation of monocyte-derived dendritic cells with toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration
    • Boullart AC, Aarntzen EH, Verdijk P, Jacobs JF, Schuurhuis DH, Benitez-Ribas D, et al. Maturation of monocyte-derived dendritic cells with toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration. Cancer Immunol Immunother (2008) 57(11):1589-97. doi:10.1007/s00262-008-0489-2.
    • (2008) Cancer Immunol Immunother , vol.57 , Issue.11 , pp. 1589-1597
    • Boullart, A.C.1    Aarntzen, E.H.2    Verdijk, P.3    Jacobs, J.F.4    Schuurhuis, D.H.5    Benitez-Ribas, D.6
  • 19
    • 84885161067 scopus 로고    scopus 로고
    • ESAT-6 and HspX improve the effectiveness of BCG to induce human dendritic cells-dependent Th1 and NK cells activation
    • Marongiu L, Donini M, Toffali L, Zenaro E, Dusi S. ESAT-6 and HspX improve the effectiveness of BCG to induce human dendritic cells-dependent Th1 and NK cells activation. PLoS One (2013) 8(10):e75684. doi:10.1371/journal.pone.0075684.
    • (2013) PLoS One , vol.8 , Issue.10
    • Marongiu, L.1    Donini, M.2    Toffali, L.3    Zenaro, E.4    Dusi, S.5
  • 20
    • 84926643779 scopus 로고    scopus 로고
    • Enhanced dendritic cell-mediated antigen-specific CD4+ T cell responses: IFN-gamma aids TLR stimulation
    • 516749
    • Sheng KC, Day S, Wright MD, Stojanovska L, Apostolopoulos V. Enhanced dendritic cell-mediated antigen-specific CD4+ T cell responses: IFN-gamma aids TLR stimulation. J Drug Deliv (2013) 2013:516749. doi:10.1155/2013/516749.
    • (2013) J Drug Deliv , vol.2013
    • Sheng, K.C.1    Day, S.2    Wright, M.D.3    Stojanovska, L.4    Apostolopoulos, V.5
  • 21
    • 4344596051 scopus 로고    scopus 로고
    • Alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity
    • Mailliard RB, Wankowicz-Kalinska A, Cai Q, Wesa A, Hilkens CM, Kapsenberg ML, et al. Alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity. Cancer Res (2004) 64(17):5934-7. doi:10.1158/0008-5472.CAN-04-1261.
    • (2004) Cancer Res , vol.64 , Issue.17 , pp. 5934-5937
    • Mailliard, R.B.1    Wankowicz-Kalinska, A.2    Cai, Q.3    Wesa, A.4    Hilkens, C.M.5    Kapsenberg, M.L.6
  • 22
    • 84866697418 scopus 로고    scopus 로고
    • Cellular based cancer vaccines: type 1 polarization of dendritic cells
    • Hansen M, Met O, Svane IM, Andersen MH. Cellular based cancer vaccines: type 1 polarization of dendritic cells. Curr Med Chem (2012) 19(25):4239-46. doi:10.2174/092986712802884213.
    • (2012) Curr Med Chem , vol.19 , Issue.25 , pp. 4239-4246
    • Hansen, M.1    Met, O.2    Svane, I.M.3    Andersen, M.H.4
  • 23
    • 0037446537 scopus 로고    scopus 로고
    • Mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors
    • Dauer M, Obermaier B, Herten J, Haerle C, Pohl K, Rothenfusser S, et al. Mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors. J Immunol (2003) 170(8):4069-76. doi:10.4049/jimmunol.170.8.4069.
    • (2003) J Immunol , vol.170 , Issue.8 , pp. 4069-4076
    • Dauer, M.1    Obermaier, B.2    Herten, J.3    Haerle, C.4    Pohl, K.5    Rothenfusser, S.6
  • 24
    • 77956222584 scopus 로고    scopus 로고
    • Generation of Th1-polarizing dendritic cells using the TLR7/8 agonist CL075
    • Spranger S, Javorovic M, Burdek M, Wilde S, Mosetter B, Tippmer S, et al. Generation of Th1-polarizing dendritic cells using the TLR7/8 agonist CL075. J Immunol (2010) 185(1):738-47. doi:10.4049/jimmunol.1000060.
    • (2010) J Immunol , vol.185 , Issue.1 , pp. 738-747
    • Spranger, S.1    Javorovic, M.2    Burdek, M.3    Wilde, S.4    Mosetter, B.5    Tippmer, S.6
  • 25
    • 77955419468 scopus 로고    scopus 로고
    • Langerhans cells and dermal dendritic cells capture protein antigens in the skin: possible targets for vaccination through the skin
    • Sparber F, Tripp CH, Hermann M, Romani N, Stoitzner P. Langerhans cells and dermal dendritic cells capture protein antigens in the skin: possible targets for vaccination through the skin. Immunobiology (2010) 215(9-10):770-9. doi:10.1016/j.imbio.2010.05.014.
    • (2010) Immunobiology , vol.215 , Issue.9-10 , pp. 770-779
    • Sparber, F.1    Tripp, C.H.2    Hermann, M.3    Romani, N.4    Stoitzner, P.5
  • 26
    • 77958454596 scopus 로고    scopus 로고
    • Designing vaccines based on biology of human dendritic cell subsets
    • Palucka K, Banchereau J, Mellman I. Designing vaccines based on biology of human dendritic cell subsets. Immunity (2010) 33(4):464-78. doi:10.1016/j.immuni.2010.10.007.
    • (2010) Immunity , vol.33 , Issue.4 , pp. 464-478
    • Palucka, K.1    Banchereau, J.2    Mellman, I.3
  • 27
    • 84883806063 scopus 로고    scopus 로고
    • Skin-resident antigen-presenting cells: instruction manual for vaccine development
    • Fehres CM, Garcia-Vallejo JJ, Unger WW, van Kooyk Y. Skin-resident antigen-presenting cells: instruction manual for vaccine development. Front Immunol (2013) 4:157. doi:10.3389/fimmu.2013.00157.
    • (2013) Front Immunol , vol.4 , pp. 157
    • Fehres, C.M.1    Garcia-Vallejo, J.J.2    Unger, W.W.3    van Kooyk, Y.4
  • 28
    • 84905403296 scopus 로고    scopus 로고
    • Dendritic cell-targeted vaccines
    • Cohn L, Delamarre L. Dendritic cell-targeted vaccines. Front Immunol (2014) 5:255. doi:10.3389/fimmu.2014.00255.
    • (2014) Front Immunol , vol.5 , pp. 255
    • Cohn, L.1    Delamarre, L.2
  • 29
    • 84878469107 scopus 로고    scopus 로고
    • Persistent antigen at vaccination sites induces tumor-specific CD8(+) T cell sequestration, dysfunction and deletion
    • Hailemichael Y, Dai Z, Jaffarzad N, Ye Y, Medina MA, Huang XF, et al. Persistent antigen at vaccination sites induces tumor-specific CD8(+) T cell sequestration, dysfunction and deletion. Nat Med (2013) 19(4):465-72. doi:10.1038/nm.3105.
    • (2013) Nat Med , vol.19 , Issue.4 , pp. 465-472
    • Hailemichael, Y.1    Dai, Z.2    Jaffarzad, N.3    Ye, Y.4    Medina, M.A.5    Huang, X.F.6
  • 30
    • 77953622301 scopus 로고    scopus 로고
    • Adjuvants for cancer vaccines
    • Dubensky TW Jr, Reed SG. Adjuvants for cancer vaccines. Semin Immunol (2010) 22(3):155-61. doi:10.1016/j.smim.2010.04.007.
    • (2010) Semin Immunol , vol.22 , Issue.3 , pp. 155-161
    • Dubensky, T.W.1    Reed, S.G.2
  • 31
    • 0141993954 scopus 로고    scopus 로고
    • Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control
    • Mullins DW, Sheasley SL, Ream RM, Bullock TN, Fu YX, Engelhard VH. Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control. J Exp Med (2003) 198(7):1023-34. doi:10.1084/jem.20021348.
    • (2003) J Exp Med , vol.198 , Issue.7 , pp. 1023-1034
    • Mullins, D.W.1    Sheasley, S.L.2    Ream, R.M.3    Bullock, T.N.4    Fu, Y.X.5    Engelhard, V.H.6
  • 32
    • 80052439234 scopus 로고    scopus 로고
    • Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients
    • Lesterhuis WJ, de Vries IJ, Schreibelt G, Lambeck AJ, Aarntzen EH, Jacobs JF, et al. Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients. Clin Cancer Res (2011) 17(17):5725-35. doi:10.1158/1078-0432.CCR-11-1261.
    • (2011) Clin Cancer Res , vol.17 , Issue.17 , pp. 5725-5735
    • Lesterhuis, W.J.1    de Vries, I.J.2    Schreibelt, G.3    Lambeck, A.J.4    Aarntzen, E.H.5    Jacobs, J.F.6
  • 33
    • 0034735552 scopus 로고    scopus 로고
    • The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments
    • Mahnke K, Guo M, Lee S, Sepulveda H, Swain SL, Nussenzweig M, et al. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J Cell Biol (2000) 151(3):673-84. doi:10.1083/jcb.151.3.673.
    • (2000) J Cell Biol , vol.151 , Issue.3 , pp. 673-684
    • Mahnke, K.1    Guo, M.2    Lee, S.3    Sepulveda, H.4    Swain, S.L.5    Nussenzweig, M.6
  • 34
    • 0037122011 scopus 로고    scopus 로고
    • Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance
    • Bonifaz L, Bonnyay D, Mahnke K, Rivera M, Nussenzweig MC, Steinman RM. Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J Exp Med (2002) 196(12):1627-38. doi:10.1084/jem.20021598.
    • (2002) J Exp Med , vol.196 , Issue.12 , pp. 1627-1638
    • Bonifaz, L.1    Bonnyay, D.2    Mahnke, K.3    Rivera, M.4    Nussenzweig, M.C.5    Steinman, R.M.6
  • 35
    • 84863664792 scopus 로고    scopus 로고
    • Antibody-antigen-adjuvant conjugates enable co-delivery of antigen and adjuvant to dendritic cells in cis but only have partial targeting specificity
    • Kreutz M, Giquel B, Hu Q, Abuknesha R, Uematsu S, Akira S, et al. Antibody-antigen-adjuvant conjugates enable co-delivery of antigen and adjuvant to dendritic cells in cis but only have partial targeting specificity. PLoS One (2012) 7(7):e40208. doi:10.1371/journal.pone.0040208.
    • (2012) PLoS One , vol.7 , Issue.7
    • Kreutz, M.1    Giquel, B.2    Hu, Q.3    Abuknesha, R.4    Uematsu, S.5    Akira, S.6
  • 36
    • 84874462885 scopus 로고    scopus 로고
    • Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery
    • Bouvier I, Jusforgues-Saklani H, Lim A, Lemaitre F, Lemercier B, Auriau C, et al. Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery. Front Immunol (2011) 2:71. doi:10.3389/fimmu.2011.00071.
    • (2011) Front Immunol , vol.2 , pp. 71
    • Bouvier, I.1    Jusforgues-Saklani, H.2    Lim, A.3    Lemaitre, F.4    Lemercier, B.5    Auriau, C.6
  • 37
    • 79951813688 scopus 로고    scopus 로고
    • Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine
    • Hangalapura BN, Oosterhoff D, Gupta T, de Groot J, Wijnands PG, van Beusechem VW, et al. Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine. Vaccine (2011) 29(12):2313-21. doi:10.1016/j.vaccine.2011.01.022.
    • (2011) Vaccine , vol.29 , Issue.12 , pp. 2313-2321
    • Hangalapura, B.N.1    Oosterhoff, D.2    Gupta, T.3    de Groot, J.4    Wijnands, P.G.5    van Beusechem, V.W.6
  • 38
    • 77952369973 scopus 로고    scopus 로고
    • Selective and site-specific mobilization of dermal dendritic cells and Langerhans cells by Th1-and Th2-polarizing adjuvants
    • Sen D, Forrest L, Kepler TB, Parker I, Cahalan MD. Selective and site-specific mobilization of dermal dendritic cells and Langerhans cells by Th1-and Th2-polarizing adjuvants. Proc Natl Acad Sci U S A (2010) 107(18):8334-9. doi:10.1073/pnas.0912817107.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.18 , pp. 8334-8339
    • Sen, D.1    Forrest, L.2    Kepler, T.B.3    Parker, I.4    Cahalan, M.D.5
  • 39
    • 84863619846 scopus 로고    scopus 로고
    • Human macrophages and dendritic cells can equally present MART-1 antigen to CD8(+) T cells after phagocytosis of gamma-irradiated melanoma cells
    • Barrio MM, Abes R, Colombo M, Pizzurro G, Boix C, Roberti MP, et al. Human macrophages and dendritic cells can equally present MART-1 antigen to CD8(+) T cells after phagocytosis of gamma-irradiated melanoma cells. PLoS One (2012) 7(7):e40311. doi:10.1371/journal.pone.0040311.
    • (2012) PLoS One , vol.7 , Issue.7
    • Barrio, M.M.1    Abes, R.2    Colombo, M.3    Pizzurro, G.4    Boix, C.5    Roberti, M.P.6
  • 40
    • 84868206060 scopus 로고    scopus 로고
    • Microneedles for drug and vaccine delivery
    • Kim YC, Park JH, Prausnitz MR. Microneedles for drug and vaccine delivery. Adv Drug Deliv Rev (2012) 64(14):1547-68. doi:10.1016/j.addr.2012.04.005.
    • (2012) Adv Drug Deliv Rev , vol.64 , Issue.14 , pp. 1547-1568
    • Kim, Y.C.1    Park, J.H.2    Prausnitz, M.R.3
  • 41
    • 84911495682 scopus 로고    scopus 로고
    • Microneedle patches for vaccine delivery
    • Suh H, Shin J, Kim YC. Microneedle patches for vaccine delivery. Clin Exp Vaccine Res (2014) 3(1):42-9. doi:10.7774/cevr.2014.3.1.42.
    • (2014) Clin Exp Vaccine Res , vol.3 , Issue.1 , pp. 42-49
    • Suh, H.1    Shin, J.2    Kim, Y.C.3
  • 42
    • 84875674290 scopus 로고    scopus 로고
    • Skin dendritic cell targeting via microneedle arrays laden with antigen-encapsulated poly-D, L-lactide-co-glycolide nanoparticles induces efficient antitumor and antiviral immune responses
    • Zaric M, Lyubomska O, Touzelet O, Poux C, Al-Zahrani S, Fay F, et al. Skin dendritic cell targeting via microneedle arrays laden with antigen-encapsulated poly-D, L-lactide-co-glycolide nanoparticles induces efficient antitumor and antiviral immune responses. ACS Nano (2013) 7(3):2042-55. doi:10.1021/nn304235j.
    • (2013) ACS Nano , vol.7 , Issue.3 , pp. 2042-2055
    • Zaric, M.1    Lyubomska, O.2    Touzelet, O.3    Poux, C.4    Al-Zahrani, S.5    Fay, F.6
  • 43
    • 84872184215 scopus 로고    scopus 로고
    • Vaccine injection site matters: qualitative and quantitative defects in CD8 T cells primed as a function of proximity to the tumor in a murine glioma model
    • Ohlfest JR, Andersen BM, Litterman AJ, Xia J, Pennell CA, Swier LE, et al. Vaccine injection site matters: qualitative and quantitative defects in CD8 T cells primed as a function of proximity to the tumor in a murine glioma model. J Immunol (2013) 190(2):613-20. doi:10.4049/jimmunol.1201557.
    • (2013) J Immunol , vol.190 , Issue.2 , pp. 613-620
    • Ohlfest, J.R.1    Andersen, B.M.2    Litterman, A.J.3    Xia, J.4    Pennell, C.A.5    Swier, L.E.6
  • 44
    • 84880446912 scopus 로고    scopus 로고
    • IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation
    • Lindenberg JJ, Oosterhoff D, Sombroek CC, Lougheed SM, Hooijberg E, Stam AG, et al. IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation. PLoS One (2013) 8(7):e70237. doi:10.1371/journal.pone.0070237.
    • (2013) PLoS One , vol.8 , Issue.7
    • Lindenberg, J.J.1    Oosterhoff, D.2    Sombroek, C.C.3    Lougheed, S.M.4    Hooijberg, E.5    Stam, A.G.6
  • 45
    • 78649663452 scopus 로고    scopus 로고
    • Vaccination with dendritic cells charged with apoptotic/necrotic B16 melanoma induces the formation of subcutaneous lymphoid tissue
    • Mac Keon S, Gazzaniga S, Mallerman J, Bravo AI, Mordoh J, Wainstok R. Vaccination with dendritic cells charged with apoptotic/necrotic B16 melanoma induces the formation of subcutaneous lymphoid tissue. Vaccine (2010) 28(51):8162-8. doi:10.1016/j.vaccine.2010.09.095.
    • (2010) Vaccine , vol.28 , Issue.51 , pp. 8162-8168
    • Mac Keon, S.1    Gazzaniga, S.2    Mallerman, J.3    Bravo, A.I.4    Mordoh, J.5    Wainstok, R.6
  • 46
    • 84155163017 scopus 로고    scopus 로고
    • The vaccine-site microenvironment induced by injection of incomplete Freund's adjuvant, with or without melanoma peptides
    • Harris RC, Chianese-Bullock KA, Petroni GR, Schaefer JT, Brill LB II, Molhoek KR, et al. The vaccine-site microenvironment induced by injection of incomplete Freund's adjuvant, with or without melanoma peptides. J Immunother (2012) 35(1):78-88. doi:10.1097/CJI.0b013e31823731a4.
    • (2012) J Immunother , vol.35 , Issue.1 , pp. 78-88
    • Harris, R.C.1    Chianese-Bullock, K.A.2    Petroni, G.R.3    Schaefer, J.T.4    Brill, L.B.5    Molhoek, K.R.6
  • 47
    • 84907980704 scopus 로고    scopus 로고
    • In situ modulation of dendritic cells by injectable thermosensitive hydrogels for cancer vaccines in mice
    • Liu Y, Xiao L, Joo KI, Hu B, Fang J, Wang P. In situ modulation of dendritic cells by injectable thermosensitive hydrogels for cancer vaccines in mice. Biomacromolecules (2014) 15(10):3836-45. doi:10.1021/bm501166j.
    • (2014) Biomacromolecules , vol.15 , Issue.10 , pp. 3836-3845
    • Liu, Y.1    Xiao, L.2    Joo, K.I.3    Hu, B.4    Fang, J.5    Wang, P.6
  • 48
    • 84896404260 scopus 로고    scopus 로고
    • Engineering vaccines and niches for immune modulation
    • Purwada A, Roy K, Singh A. Engineering vaccines and niches for immune modulation. Acta Biomater (2014) 10(4):1728-40. doi:10.1016/j.actbio.2013.12.036.
    • (2014) Acta Biomater , vol.10 , Issue.4 , pp. 1728-1740
    • Purwada, A.1    Roy, K.2    Singh, A.3
  • 49
    • 84924367334 scopus 로고    scopus 로고
    • Chemokines as cancer vaccine adjuvants
    • Bobanga ID, Petrosiute A, Huang AY. Chemokines as cancer vaccine adjuvants. Vaccines (Basel) (2013) 1(4):444-62. doi:10.3390/vaccines1040444.
    • (2013) Vaccines (Basel) , vol.1 , Issue.4 , pp. 444-462
    • Bobanga, I.D.1    Petrosiute, A.2    Huang, A.Y.3
  • 50
    • 67449101536 scopus 로고    scopus 로고
    • Conditioning vaccination site with irradiated MIP-3alpha-transfected tumor cells enhances efficacy of dendritic cell-based cancer vaccine
    • Shih NY, Yang HY, Cheng HT, Hung YM, Yao YC, Zhu YH, et al. Conditioning vaccination site with irradiated MIP-3alpha-transfected tumor cells enhances efficacy of dendritic cell-based cancer vaccine. J Immunother (2009) 32(4):363-9. doi:10.1097/CJI.0b013e31819d29d8.
    • (2009) J Immunother , vol.32 , Issue.4 , pp. 363-369
    • Shih, N.Y.1    Yang, H.Y.2    Cheng, H.T.3    Hung, Y.M.4    Yao, Y.C.5    Zhu, Y.H.6
  • 51
    • 1342287192 scopus 로고    scopus 로고
    • MIP-1alpha antagonizes the effect of a GM-CSF-enhanced subcutaneous vaccine in a mouse glioma model
    • Herrlinger U, Aulwurm S, Strik H, Weit S, Naumann U, Weller M. MIP-1alpha antagonizes the effect of a GM-CSF-enhanced subcutaneous vaccine in a mouse glioma model. J Neurooncol (2004) 66(1-2):147-54. doi:10.1023/B:NEON.0000013497.04322.fc.
    • (2004) J Neurooncol , vol.66 , Issue.1-2 , pp. 147-154
    • Herrlinger, U.1    Aulwurm, S.2    Strik, H.3    Weit, S.4    Naumann, U.5    Weller, M.6
  • 52
    • 77957982756 scopus 로고    scopus 로고
    • Toll-like receptor agonists: are they good adjuvants?
    • Gnjatic S, Sawhney NB, Bhardwaj N. Toll-like receptor agonists: are they good adjuvants? Cancer J (2010) 16(4):382-91. doi:10.1097/PPO.0b013e3181eaca65.
    • (2010) Cancer J , vol.16 , Issue.4 , pp. 382-391
    • Gnjatic, S.1    Sawhney, N.B.2    Bhardwaj, N.3
  • 53
    • 84888347277 scopus 로고    scopus 로고
    • Adjuvants that improve the ratio of antigen-specific effector to regulatory T cells enhance tumor immunity
    • Perret R, Sierro SR, Botelho NK, Corgnac S, Donda A, Romero P. Adjuvants that improve the ratio of antigen-specific effector to regulatory T cells enhance tumor immunity. Cancer Res (2013) 73(22):6597-608. doi:10.1158/0008-5472.CAN-13-0875.
    • (2013) Cancer Res , vol.73 , Issue.22 , pp. 6597-6608
    • Perret, R.1    Sierro, S.R.2    Botelho, N.K.3    Corgnac, S.4    Donda, A.5    Romero, P.6
  • 54
    • 84868094428 scopus 로고    scopus 로고
    • Nano-particle vaccination combined with TLR-7 and-9 ligands triggers memory and effector CD8(+) T-cell responses in melanoma patients
    • Goldinger SM, Dummer R, Baumgaertner P, Mihic-Probst D, Schwarz K, Hammann-Haenni A, et al. Nano-particle vaccination combined with TLR-7 and-9 ligands triggers memory and effector CD8(+) T-cell responses in melanoma patients. Eur J Immunol (2012) 42(11):3049-61. doi:10.1002/eji.201142361.
    • (2012) Eur J Immunol , vol.42 , Issue.11 , pp. 3049-3061
    • Goldinger, S.M.1    Dummer, R.2    Baumgaertner, P.3    Mihic-Probst, D.4    Schwarz, K.5    Hammann-Haenni, A.6
  • 55
    • 84886944629 scopus 로고    scopus 로고
    • Injection site and regulatory T cells influence durable vaccine-induced tumor immunity to an over-expressed self tumor associated antigen
    • Bright JD, Schultz HN, Byrne JA, Bright RK. Injection site and regulatory T cells influence durable vaccine-induced tumor immunity to an over-expressed self tumor associated antigen. Oncoimmunology (2013) 2(7):e25049. doi:10.4161/onci.25049.
    • (2013) Oncoimmunology , vol.2 , Issue.7
    • Bright, J.D.1    Schultz, H.N.2    Byrne, J.A.3    Bright, R.K.4
  • 56
    • 84861787202 scopus 로고    scopus 로고
    • Dendritic cell-activating vaccine adjuvants differ in the ability to elicit antitumor immunity due to an adjuvant-specific induction of immunosuppressive cells
    • Dang Y, Wagner WM, Gad E, Rastetter L, Berger CM, Holt GE, et al. Dendritic cell-activating vaccine adjuvants differ in the ability to elicit antitumor immunity due to an adjuvant-specific induction of immunosuppressive cells. Clin Cancer Res (2012) 18(11):3122-31. doi:10.1158/1078-0432.CCR-12-0113.
    • (2012) Clin Cancer Res , vol.18 , Issue.11 , pp. 3122-3131
    • Dang, Y.1    Wagner, W.M.2    Gad, E.3    Rastetter, L.4    Berger, C.M.5    Holt, G.E.6
  • 57
    • 84906078348 scopus 로고    scopus 로고
    • Topical rather than intradermal application of the TLR7 ligand imiquimod leads to human dermal dendritic cell maturation and CD8+ T-cell cross-priming
    • Fehres CM, Bruijns SC, van Beelen AJ, Kalay H, Ambrosini M, Hooijberg E, et al. Topical rather than intradermal application of the TLR7 ligand imiquimod leads to human dermal dendritic cell maturation and CD8+ T-cell cross-priming. Eur J Immunol (2014) 44(8):2415-24. doi:10.1002/eji.201344094.
    • (2014) Eur J Immunol , vol.44 , Issue.8 , pp. 2415-2424
    • Fehres, C.M.1    Bruijns, S.C.2    van Beelen, A.J.3    Kalay, H.4    Ambrosini, M.5    Hooijberg, E.6
  • 58
    • 79960413988 scopus 로고    scopus 로고
    • ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells
    • Duewell P, Kisser U, Heckelsmiller K, Hoves S, Stoitzner P, Koernig S, et al. ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells. J Immunol (2011) 187(1):55-63. doi:10.4049/jimmunol.1004114.
    • (2011) J Immunol , vol.187 , Issue.1 , pp. 55-63
    • Duewell, P.1    Kisser, U.2    Heckelsmiller, K.3    Hoves, S.4    Stoitzner, P.5    Koernig, S.6
  • 59
    • 33645866471 scopus 로고    scopus 로고
    • Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction
    • Castellino F, Huang AY, Altan-Bonnet G, Stoll S, Scheinecker C, Germain RN. Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction. Nature (2006) 440(7086):890-5. doi:10.1038/nature04651.
    • (2006) Nature , vol.440 , Issue.7086 , pp. 890-895
    • Castellino, F.1    Huang, A.Y.2    Altan-Bonnet, G.3    Stoll, S.4    Scheinecker, C.5    Germain, R.N.6
  • 60
    • 84901823341 scopus 로고    scopus 로고
    • T cell migration in intact lymph nodes in vivo
    • Munoz MA, Biro M, Weninger W. T cell migration in intact lymph nodes in vivo. Curr Opin Cell Biol (2014) 30C:17-24. doi:10.1016/j.ceb.2014.05.002.
    • (2014) Curr Opin Cell Biol , vol.30 C , pp. 17-24
    • Munoz, M.A.1    Biro, M.2    Weninger, W.3
  • 61
    • 84899991702 scopus 로고    scopus 로고
    • Taking the lymphatic route: dendritic cell migration to draining lymph nodes
    • Teijeira A, Russo E, Halin C. Taking the lymphatic route: dendritic cell migration to draining lymph nodes. Semin Immunopathol (2014) 36(2):261-74. doi:10.1007/s00281-013-0410-8.
    • (2014) Semin Immunopathol , vol.36 , Issue.2 , pp. 261-274
    • Teijeira, A.1    Russo, E.2    Halin, C.3
  • 62
    • 34548654992 scopus 로고    scopus 로고
    • Controls for lung dendritic cell maturation and migration during respiratory viral infection
    • Grayson MH, Ramos MS, Rohlfing MM, Kitchens R, Wang HD, Gould A, et al. Controls for lung dendritic cell maturation and migration during respiratory viral infection. J Immunol (2007) 179(3):1438-48. doi:10.4049/jimmunol.179.3.1438.
    • (2007) J Immunol , vol.179 , Issue.3 , pp. 1438-1448
    • Grayson, M.H.1    Ramos, M.S.2    Rohlfing, M.M.3    Kitchens, R.4    Wang, H.D.5    Gould, A.6
  • 63
    • 0742323358 scopus 로고    scopus 로고
    • T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node
    • Miller MJ, Hejazi AS, Wei SH, Cahalan MD, Parker I. T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node. Proc Natl Acad Sci U S A (2004) 101(4):998-1003. doi:10.1073/pnas.0306407101.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.4 , pp. 998-1003
    • Miller, M.J.1    Hejazi, A.S.2    Wei, S.H.3    Cahalan, M.D.4    Parker, I.5
  • 64
    • 84868156968 scopus 로고    scopus 로고
    • Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naive CD4+ and CD8+ T cells
    • Mandl JN, Liou R, Klauschen F, Vrisekoop N, Monteiro JP, Yates AJ, et al. Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naive CD4+ and CD8+ T cells. Proc Natl Acad Sci U S A (2012) 109(44):18036-41. doi:10.1073/pnas.1211717109.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.44 , pp. 18036-18041
    • Mandl, J.N.1    Liou, R.2    Klauschen, F.3    Vrisekoop, N.4    Monteiro, J.P.5    Yates, A.J.6
  • 65
    • 23444441823 scopus 로고    scopus 로고
    • CC chemokine ligand 19 secreted by mature dendritic cells increases naive T cell scanning behavior and their response to rare cognate antigen
    • Kaiser A, Donnadieu E, Abastado JP, Trautmann A, Nardin A. CC chemokine ligand 19 secreted by mature dendritic cells increases naive T cell scanning behavior and their response to rare cognate antigen. J Immunol (2005) 175(4):2349-56. doi:10.4049/jimmunol.175.4.2349.
    • (2005) J Immunol , vol.175 , Issue.4 , pp. 2349-2356
    • Kaiser, A.1    Donnadieu, E.2    Abastado, J.P.3    Trautmann, A.4    Nardin, A.5
  • 66
    • 0037501371 scopus 로고    scopus 로고
    • Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes
    • Bousso P, Robey E. Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes. Nat Immunol (2003) 4(6):579-85. doi:10.1038/ni928.
    • (2003) Nat Immunol , vol.4 , Issue.6 , pp. 579-585
    • Bousso, P.1    Robey, E.2
  • 67
    • 34548131114 scopus 로고    scopus 로고
    • Dynamic imaging of chemokine-dependent CD8+ T cell help for CD8+ T cell responses
    • Hugues S, Scholer A, Boissonnas A, Nussbaum A, Combadiere C, Amigorena S, et al. Dynamic imaging of chemokine-dependent CD8+ T cell help for CD8+ T cell responses. Nat Immunol (2007) 8(9):921-30. doi:10.1038/ni1495.
    • (2007) Nat Immunol , vol.8 , Issue.9 , pp. 921-930
    • Hugues, S.1    Scholer, A.2    Boissonnas, A.3    Nussbaum, A.4    Combadiere, C.5    Amigorena, S.6
  • 68
    • 0037226599 scopus 로고    scopus 로고
    • Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state
    • de Vries IJ, Krooshoop DJ, Scharenborg NM, Lesterhuis WJ, Diepstra JH, Van Muijen GN, et al. Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res (2003) 63(1):12-7.
    • (2003) Cancer Res , vol.63 , Issue.1 , pp. 12-17
    • de Vries, I.J.1    Krooshoop, D.J.2    Scharenborg, N.M.3    Lesterhuis, W.J.4    Diepstra, J.H.5    Van Muijen, G.N.6
  • 69
    • 33645995745 scopus 로고    scopus 로고
    • The multiple personalities of the chemokine receptor CCR7 in dendritic cells
    • Sanchez-Sanchez N, Riol-Blanco L, Rodriguez-Fernandez JL. The multiple personalities of the chemokine receptor CCR7 in dendritic cells. J Immunol (2006) 176(9):5153-9. doi:10.4049/jimmunol.176.9.5153.
    • (2006) J Immunol , vol.176 , Issue.9 , pp. 5153-5159
    • Sanchez-Sanchez, N.1    Riol-Blanco, L.2    Rodriguez-Fernandez, J.L.3
  • 70
    • 84877785185 scopus 로고    scopus 로고
    • Co-transfection gene delivery of dendritic cells induced effective lymph node targeting and anti-tumor vaccination
    • Chen YZ, Ruan GX, Yao XL, Li LM, Hu Y, Tabata Y, et al. Co-transfection gene delivery of dendritic cells induced effective lymph node targeting and anti-tumor vaccination. Pharm Res (2013) 30(6):1502-12. doi:10.1007/s11095-013-0985-8.
    • (2013) Pharm Res , vol.30 , Issue.6 , pp. 1502-1512
    • Chen, Y.Z.1    Ruan, G.X.2    Yao, X.L.3    Li, L.M.4    Hu, Y.5    Tabata, Y.6
  • 71
    • 0042922810 scopus 로고    scopus 로고
    • Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming
    • MartIn-Fontecha A, Sebastiani S, Hopken UE, Uguccioni M, Lipp M, Lanzavecchia A, et al. Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med (2003) 198(4):615-21. doi:10.1084/jem.20030448.
    • (2003) J Exp Med , vol.198 , Issue.4 , pp. 615-621
    • MartIn-Fontecha, A.1    Sebastiani, S.2    Hopken, U.E.3    Uguccioni, M.4    Lipp, M.5    Lanzavecchia, A.6
  • 72
    • 84896532703 scopus 로고    scopus 로고
    • Lymphatic specific disruption in the fine structure of heparan sulfate inhibits dendritic cell traffic and functional T cell responses in the lymph node
    • Yin X, Johns SC, Kim D, Mikulski Z, Salanga CL, Handel TM, et al. Lymphatic specific disruption in the fine structure of heparan sulfate inhibits dendritic cell traffic and functional T cell responses in the lymph node. J Immunol (2014) 192(5):2133-42. doi:10.4049/jimmunol.1301286.
    • (2014) J Immunol , vol.192 , Issue.5 , pp. 2133-2142
    • Yin, X.1    Johns, S.C.2    Kim, D.3    Mikulski, Z.4    Salanga, C.L.5    Handel, T.M.6
  • 73
    • 0036568954 scopus 로고    scopus 로고
    • Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin
    • Ratzinger G, Stoitzner P, Ebner S, Lutz MB, Layton GT, Rainer C, et al. Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin. J Immunol (2002) 168(9):4361-71. doi:10.4049/jimmunol.168.9.4361.
    • (2002) J Immunol , vol.168 , Issue.9 , pp. 4361-4371
    • Ratzinger, G.1    Stoitzner, P.2    Ebner, S.3    Lutz, M.B.4    Layton, G.T.5    Rainer, C.6
  • 74
    • 84898905099 scopus 로고    scopus 로고
    • Control of dendritic cell trafficking in lymphatics by chemokines
    • Johnson LA, Jackson DG. Control of dendritic cell trafficking in lymphatics by chemokines. Angiogenesis (2014) 17(2):335-45. doi:10.1007/s10456-013-9407-0.
    • (2014) Angiogenesis , vol.17 , Issue.2 , pp. 335-345
    • Johnson, L.A.1    Jackson, D.G.2
  • 75
    • 84875183933 scopus 로고    scopus 로고
    • Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells
    • Aarntzen EH, Srinivas M, Bonetto F, Cruz LJ, Verdijk P, Schreibelt G, et al. Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells. Clin Cancer Res (2013) 19(6):1525-33. doi:10.1158/1078-0432.CCR-12-1879.
    • (2013) Clin Cancer Res , vol.19 , Issue.6 , pp. 1525-1533
    • Aarntzen, E.H.1    Srinivas, M.2    Bonetto, F.3    Cruz, L.J.4    Verdijk, P.5    Schreibelt, G.6
  • 78
    • 84878459627 scopus 로고    scopus 로고
    • Using magnetic resonance imaging to evaluate dendritic cell-based vaccination
    • Ferguson PM, Slocombe A, Tilley RD, Hermans IF. Using magnetic resonance imaging to evaluate dendritic cell-based vaccination. PLoS One (2013) 8(5):e65318. doi:10.1371/journal.pone.0065318.
    • (2013) PLoS One , vol.8 , Issue.5
    • Ferguson, P.M.1    Slocombe, A.2    Tilley, R.D.3    Hermans, I.F.4
  • 79
    • 33748750776 scopus 로고    scopus 로고
    • The tumor-draining lymph node as an immune-privileged site
    • Munn DH, Mellor AL. The tumor-draining lymph node as an immune-privileged site. Immunol Rev (2006) 213:146-58. doi:10.1111/j.1600-065X.2006.00444.x.
    • (2006) Immunol Rev , vol.213 , pp. 146-158
    • Munn, D.H.1    Mellor, A.L.2
  • 80
    • 79953870552 scopus 로고    scopus 로고
    • Immune response to cancer and its regulation in regional lymph nodes
    • Zheng R, Shu S. Immune response to cancer and its regulation in regional lymph nodes. J Surg Oncol (2011) 103(6):550-4. doi:10.1002/jso.21692.
    • (2011) J Surg Oncol , vol.103 , Issue.6 , pp. 550-554
    • Zheng, R.1    Shu, S.2
  • 81
    • 84908589994 scopus 로고    scopus 로고
    • Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes
    • Jeanbart L, Ballester M, de Titta A, Corthesy P, Romero P, Hubbell JA, et al. Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes. Cancer Immunol Res (2014) 2(5):436-47. doi:10.1158/2326-6066.CIR-14-0019-T.
    • (2014) Cancer Immunol Res , vol.2 , Issue.5 , pp. 436-447
    • Jeanbart, L.1    Ballester, M.2    de Titta, A.3    Corthesy, P.4    Romero, P.5    Hubbell, J.A.6
  • 82
    • 77149142263 scopus 로고    scopus 로고
    • Foxp3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes
    • Boissonnas A, Scholer-Dahirel A, Simon-Blancal V, Pace L, Valet F, Kissenpfennig A, et al. Foxp3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes. Immunity (2010) 32(2):266-78. doi:10.1016/j.immuni.2009.11.015.
    • (2010) Immunity , vol.32 , Issue.2 , pp. 266-278
    • Boissonnas, A.1    Scholer-Dahirel, A.2    Simon-Blancal, V.3    Pace, L.4    Valet, F.5    Kissenpfennig, A.6
  • 83
    • 84884796701 scopus 로고    scopus 로고
    • Spatial organization of dendritic cells within tumor draining lymph nodes impacts clinical outcome in breast cancer patients
    • Chang AY, Bhattacharya N, Mu J, Setiadi AF, Carcamo-Cavazos V, Lee GH, et al. Spatial organization of dendritic cells within tumor draining lymph nodes impacts clinical outcome in breast cancer patients. J Transl Med (2013) 11:242. doi:10.1186/1479-5876-11-242.
    • (2013) J Transl Med , vol.11 , pp. 242
    • Chang, A.Y.1    Bhattacharya, N.2    Mu, J.3    Setiadi, A.F.4    Carcamo-Cavazos, V.5    Lee, G.H.6
  • 84
    • 80052406212 scopus 로고    scopus 로고
    • Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation
    • van de Ven R, van den Hout MF, Lindenberg JJ, Sluijter BJ, van Leeuwen PA, Lougheed SM, et al. Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation. Blood (2011) 118(9):2502-10. doi:10.1182/blood-2011-03-344838.
    • (2011) Blood , vol.118 , Issue.9 , pp. 2502-2510
    • van de Ven, R.1    van den Hout, M.F.2    Lindenberg, J.J.3    Sluijter, B.J.4    van Leeuwen, P.A.5    Lougheed, S.M.6
  • 85
    • 84857257866 scopus 로고    scopus 로고
    • Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes
    • St John AL, Chan CY, Staats HF, Leong KW, Abraham SN. Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes. Nat Mater (2012) 11(3):250-7. doi:10.1038/nmat3222.
    • (2012) Nat Mater , vol.11 , Issue.3 , pp. 250-257
    • St John, A.L.1    Chan, C.Y.2    Staats, H.F.3    Leong, K.W.4    Abraham, S.N.5
  • 86
    • 77951639701 scopus 로고    scopus 로고
    • Activation of tolerogenic dendritic cells in the tumor draining lymph nodes by CD8+ T cells engineered to express CD40 ligand
    • Higham EM, Wittrup KD, Chen J. Activation of tolerogenic dendritic cells in the tumor draining lymph nodes by CD8+ T cells engineered to express CD40 ligand. J Immunol (2010) 184(7):3394-400. doi:10.4049/jimmunol.0903111.
    • (2010) J Immunol , vol.184 , Issue.7 , pp. 3394-3400
    • Higham, E.M.1    Wittrup, K.D.2    Chen, J.3
  • 87
    • 84896526831 scopus 로고    scopus 로고
    • NK cells are required for dendritic cell-based immunotherapy at the time of tumor challenge
    • Bouwer AL, Saunderson SC, Caldwell FJ, Damani TT, Pelham SJ, Dunn AC, et al. NK cells are required for dendritic cell-based immunotherapy at the time of tumor challenge. J Immunol (2014) 192(5):2514-21. doi:10.4049/jimmunol.1202797.
    • (2014) J Immunol , vol.192 , Issue.5 , pp. 2514-2521
    • Bouwer, A.L.1    Saunderson, S.C.2    Caldwell, F.J.3    Damani, T.T.4    Pelham, S.J.5    Dunn, A.C.6
  • 88
    • 84890258401 scopus 로고    scopus 로고
    • IL-18-based combinatorial adjuvants promote the intranodal production of CCL19 by NK cells and dendritic cells of cancer patients
    • Wong JL, Muthuswamy R, Bartlett DL, Kalinski P. IL-18-based combinatorial adjuvants promote the intranodal production of CCL19 by NK cells and dendritic cells of cancer patients. Oncoimmunology (2013) 2(9):e26245. doi:10.4161/onci.26245.
    • (2013) Oncoimmunology , vol.2 , Issue.9
    • Wong, J.L.1    Muthuswamy, R.2    Bartlett, D.L.3    Kalinski, P.4
  • 89
    • 84884311129 scopus 로고    scopus 로고
    • Antigen availability determines CD8(+) T cell-dendritic cell interaction kinetics and memory fate decisions
    • Henrickson SE, Perro M, Loughhead SM, Senman B, Stutte S, Quigley M, et al. Antigen availability determines CD8(+) T cell-dendritic cell interaction kinetics and memory fate decisions. Immunity (2013) 39(3):496-507. doi:10.1016/j.immuni.2013.08.034.
    • (2013) Immunity , vol.39 , Issue.3 , pp. 496-507
    • Henrickson, S.E.1    Perro, M.2    Loughhead, S.M.3    Senman, B.4    Stutte, S.5    Quigley, M.6
  • 90
    • 84885723472 scopus 로고    scopus 로고
    • Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation
    • Rosalia RA, Quakkelaar ED, Redeker A, Khan S, Camps M, Drijfhout JW, et al. Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation. Eur J Immunol (2013) 43(10):2554-65. doi:10.1002/eji.201343324.
    • (2013) Eur J Immunol , vol.43 , Issue.10 , pp. 2554-2565
    • Rosalia, R.A.1    Quakkelaar, E.D.2    Redeker, A.3    Khan, S.4    Camps, M.5    Drijfhout, J.W.6
  • 91
    • 84862777557 scopus 로고    scopus 로고
    • Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice
    • Wang B, Zaidi N, He LZ, Zhang L, Kuroiwa JM, Keler T, et al. Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice. Breast Cancer Res (2012) 14(2):R39. doi:10.1186/bcr3135.
    • (2012) Breast Cancer Res , vol.14 , Issue.2 , pp. R39
    • Wang, B.1    Zaidi, N.2    He, L.Z.3    Zhang, L.4    Kuroiwa, J.M.5    Keler, T.6
  • 93
    • 84887607771 scopus 로고    scopus 로고
    • TLR4 ligand formulation causes distinct effects on antigen-specific cell-mediated and humoral immune responses
    • Fox CB, Moutaftsi M, Vergara J, Desbien AL, Nana GI, Vedvick TS, et al. TLR4 ligand formulation causes distinct effects on antigen-specific cell-mediated and humoral immune responses. Vaccine (2013) 31(49):5848-55. doi:10.1016/j.vaccine.2013.09.069.
    • (2013) Vaccine , vol.31 , Issue.49 , pp. 5848-5855
    • Fox, C.B.1    Moutaftsi, M.2    Vergara, J.3    Desbien, A.L.4    Nana, G.I.5    Vedvick, T.S.6
  • 94
    • 77955411096 scopus 로고    scopus 로고
    • Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses
    • Welters MJ, Kenter GG, de Vos van Steenwijk PJ, Lowik MJ, Berends-van der Meer DM, Essahsah F, et al. Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses. Proc Natl Acad Sci U S A (2010) 107(26):11895-9. doi:10.1073/pnas.1006500107.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.26 , pp. 11895-11899
    • Welters, M.J.1    Kenter, G.G.2    de Vos van Steenwijk, P.J.3    Lowik, M.J.4    Berends-van der Meer, D.M.5    Essahsah, F.6
  • 95
    • 84906083222 scopus 로고    scopus 로고
    • Apoptotic cell capture by DCs induces unexpectedly robust autologous CD4+ T-cell responses
    • Valente M, Baey C, Louche P, Dutertre CA, Vimeux L, Maranon C, et al. Apoptotic cell capture by DCs induces unexpectedly robust autologous CD4+ T-cell responses. Eur J Immunol (2014) 44(8):2274-86. doi:10.1002/eji.201344191.
    • (2014) Eur J Immunol , vol.44 , Issue.8 , pp. 2274-2286
    • Valente, M.1    Baey, C.2    Louche, P.3    Dutertre, C.A.4    Vimeux, L.5    Maranon, C.6
  • 96
    • 84892461172 scopus 로고    scopus 로고
    • Tumor-specific CD4+ T cells maintain effector and memory tumor-specific CD8+ T cells
    • Church SE, Jensen SM, Antony PA, Restifo NP, Fox BA. Tumor-specific CD4+ T cells maintain effector and memory tumor-specific CD8+ T cells. Eur J Immunol (2014) 44(1):69-79. doi:10.1002/eji.201343718.
    • (2014) Eur J Immunol , vol.44 , Issue.1 , pp. 69-79
    • Church, S.E.1    Jensen, S.M.2    Antony, P.A.3    Restifo, N.P.4    Fox, B.A.5
  • 97
    • 77955375908 scopus 로고    scopus 로고
    • Antigen-experienced CD4(+) T cells limit naive T-cell priming in response to therapeutic vaccination in vivo
    • Schiering C, Guarnerio J, Basso V, Muzio L, Mondino A. Antigen-experienced CD4(+) T cells limit naive T-cell priming in response to therapeutic vaccination in vivo. Cancer Res (2010) 70(15):6161-70. doi:10.1158/0008-5472.CAN-09-4398.
    • (2010) Cancer Res , vol.70 , Issue.15 , pp. 6161-6170
    • Schiering, C.1    Guarnerio, J.2    Basso, V.3    Muzio, L.4    Mondino, A.5
  • 98
    • 84904402735 scopus 로고    scopus 로고
    • Selective antigen-specific CD4(+) T-cell, but not CD8(+) T-or B-cell, tolerance corrupts cancer immunotherapy
    • Snook AE, Magee MS, Schulz S, Waldman SA. Selective antigen-specific CD4(+) T-cell, but not CD8(+) T-or B-cell, tolerance corrupts cancer immunotherapy. Eur J Immunol (2014) 44(7):1956-66. doi:10.1002/eji.201444539.
    • (2014) Eur J Immunol , vol.44 , Issue.7 , pp. 1956-1966
    • Snook, A.E.1    Magee, M.S.2    Schulz, S.3    Waldman, S.A.4
  • 99
    • 84871943629 scopus 로고    scopus 로고
    • Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination
    • Aarntzen EH, De Vries IJ, Lesterhuis WJ, Schuurhuis D, Jacobs JF, Bol K, et al. Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination. Cancer Res (2013) 73(1):19-29. doi:10.1158/0008-5472.CAN-12-1127.
    • (2013) Cancer Res , vol.73 , Issue.1 , pp. 19-29
    • Aarntzen, E.H.1    De Vries, I.J.2    Lesterhuis, W.J.3    Schuurhuis, D.4    Jacobs, J.F.5    Bol, K.6
  • 100
    • 70349569569 scopus 로고    scopus 로고
    • Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
    • Ahmadzadeh M, Johnson LA, Heemskerk B, Wunderlich JR, Dudley ME, White DE, et al. Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood (2009) 114(8):1537-44. doi:10.1182/blood-2008-12-195792.
    • (2009) Blood , vol.114 , Issue.8 , pp. 1537-1544
    • Ahmadzadeh, M.1    Johnson, L.A.2    Heemskerk, B.3    Wunderlich, J.R.4    Dudley, M.E.5    White, D.E.6
  • 101
    • 84892171528 scopus 로고    scopus 로고
    • Clinical implications of co-inhibitory molecule expression in the tumor microenvironment for DC vaccination: a game of stop and go
    • Vasaturo A, Di Blasio S, Peeters DG, de Koning CC, de Vries JM, Figdor CG, et al. Clinical implications of co-inhibitory molecule expression in the tumor microenvironment for DC vaccination: a game of stop and go. Front Immunol (2013) 4:417. doi:10.3389/fimmu.2013.00417.
    • (2013) Front Immunol , vol.4 , pp. 417
    • Vasaturo, A.1    Di Blasio, S.2    Peeters, D.G.3    de Koning, C.C.4    de Vries, J.M.5    Figdor, C.G.6
  • 102
    • 84924922045 scopus 로고    scopus 로고
    • Correlation between frequencies of blood monocytic myeloid-derived suppressor cells, regulatory T cells and negative prognostic markers in patients with castration-resistant metastatic prostate cancer
    • Idorn M, Kollgaard T, Kongsted P, Sengelov L, Thor Straten P. Correlation between frequencies of blood monocytic myeloid-derived suppressor cells, regulatory T cells and negative prognostic markers in patients with castration-resistant metastatic prostate cancer. Cancer Immunol Immunother (2014) 63(11):1177-87. doi:10.1007/s00262-014-1591-2.
    • (2014) Cancer Immunol Immunother , vol.63 , Issue.11 , pp. 1177-1187
    • Idorn, M.1    Kollgaard, T.2    Kongsted, P.3    Sengelov, L.4    Thor Straten, P.5
  • 103
    • 38049129212 scopus 로고    scopus 로고
    • Circulating tumor antigen-specific regulatory T cells in patients with metastatic melanoma
    • Vence L, Palucka AK, Fay JW, Ito T, Liu YJ, Banchereau J, et al. Circulating tumor antigen-specific regulatory T cells in patients with metastatic melanoma. Proc Natl Acad Sci U S A (2007) 104(52):20884-9. doi:10.1073/pnas.0710557105.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.52 , pp. 20884-20889
    • Vence, L.1    Palucka, A.K.2    Fay, J.W.3    Ito, T.4    Liu, Y.J.5    Banchereau, J.6
  • 104
    • 84883466843 scopus 로고    scopus 로고
    • A dendritic cell vaccine pulsed with autologous hypochlorous acid-oxidized ovarian cancer lysate primes effective broad antitumor immunity: from bench to bedside
    • Chiang CL, Kandalaft LE, Tanyi J, Hagemann AR, Motz GT, Svoronos N, et al. A dendritic cell vaccine pulsed with autologous hypochlorous acid-oxidized ovarian cancer lysate primes effective broad antitumor immunity: from bench to bedside. Clin Cancer Res (2013) 19(17):4801-15. doi:10.1158/1078-0432.CCR-13-1185.
    • (2013) Clin Cancer Res , vol.19 , Issue.17 , pp. 4801-4815
    • Chiang, C.L.1    Kandalaft, L.E.2    Tanyi, J.3    Hagemann, A.R.4    Motz, G.T.5    Svoronos, N.6
  • 105
    • 77950829391 scopus 로고    scopus 로고
    • Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy
    • Takeshima T, Chamoto K, Wakita D, Ohkuri T, Togashi Y, Shirato H, et al. Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy. Cancer Res (2010) 70(7):2697-706. doi:10.1158/0008-5472.CAN-09-2982.
    • (2010) Cancer Res , vol.70 , Issue.7 , pp. 2697-2706
    • Takeshima, T.1    Chamoto, K.2    Wakita, D.3    Ohkuri, T.4    Togashi, Y.5    Shirato, H.6
  • 106
    • 84901598853 scopus 로고    scopus 로고
    • Accumulation of memory precursor CD8 T cells in regressing tumors following combination therapy with vaccine and anti-PD-1 antibody
    • Karyampudi L, Lamichhane P, Scheid AD, Kalli KR, Shreeder B, Krempski JW, et al. Accumulation of memory precursor CD8 T cells in regressing tumors following combination therapy with vaccine and anti-PD-1 antibody. Cancer Res (2014) 74(11):2974-85. doi:10.1158/0008-5472.CAN-13-2564.
    • (2014) Cancer Res , vol.74 , Issue.11 , pp. 2974-2985
    • Karyampudi, L.1    Lamichhane, P.2    Scheid, A.D.3    Kalli, K.R.4    Shreeder, B.5    Krempski, J.W.6
  • 107
    • 84864662070 scopus 로고    scopus 로고
    • Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
    • Walter S, Weinschenk T, Stenzl A, Zdrojowy R, Pluzanska A, Szczylik C, et al. Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med (2012) 18(8):1254-61. doi:10.1038/nm.2883.
    • (2012) Nat Med , vol.18 , Issue.8 , pp. 1254-1261
    • Walter, S.1    Weinschenk, T.2    Stenzl, A.3    Zdrojowy, R.4    Pluzanska, A.5    Szczylik, C.6


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