The PIGRET assay, a method for measuring Pig-a gene mutation in reticulocytes, is reliable as a short-term in vivo genotoxicity test: Summary of the MMS/JEMS-collaborative study across 16 laboratories using 24 chemicals

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 811, Issue , 2016, Pages 3-15

  Kimoto, Takafumi ^a   Horibata, Katsuyoshi ^b   Miura, Daishiro ^a   Chikura, Satsuki ^a   Okada, Yuki ^a   Ukai, Akiko ^b   Itoh, Satoru ^c   Nakayama, Shiho ^c   Sanada, Hisakazu ^d   Koyama, Naomi ^d   Muto, Shigeharu ^e   Uno, Yoshifumi ^e   Yamamoto, Mika ^f   Suzuki, Yuta ^g   Fukuda, Takayuki ^g   Goto, Ken ^g   Wada, Kunio ^h   Kyoya, Takahiro ⁱ   Shigano, Miyuki ^j   Takasawa, Hironao ^j   Hamada, Shuichi ^j   Adachi, Hideki ^k   Uematsu, Yasuaki ^k   Tsutsumi, Eri ^l   Hori, Hisako ^l   Kikuzuki, Ryuta ^m   Ogiwara, Yosuke ^m   Yoshida, Ikuma ⁿ   Maeda, Akihisa ^o   Narumi, Kazunori ^p   Fujiishi, Yohei ^p   Morita, Takeshi ^b   Yamada, Masami ^b   Honma, Masamitsu ^b   more..

^a TEIJIN PHARMA LIMITED   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c DAIICHI SANKYO CO   (Japan)

^d KAKEN PHARMACEUTICAL CO LTD   (Japan)

^e MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^f ASTELLAS PHARMA INC   (Japan)

^g Research Center Inc   (Japan)

^h INSTITUTE OF ENVIRONMENTAL TOXICOLOGY   (Japan)

ⁱ KUMIAI CHEMICAL INDUSTRY CO LTD   (Japan)

^j LSI MEDIENCE CORPORATION   (Japan)

^k DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^l SUNTORY LTD   (Japan)

^m TAISHO PHARMACEUTICAL CO LTD   (Japan)

ⁿ TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^o TORAY INDUSTRIES INC   (Japan)

^p YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

more..

Author keywords

Gene mutation; Pig a assay; PIGRET; Reticulocyte

Indexed keywords

1,2 DIMETHYLHYDRAZINE; ACRYLAMIDE; ARISTOLOCHIC ACID; AZATHIOPRINE; BENZO[A]PYRENE; CHLORAMBUCIL; CISPLATIN; DIETHYLNITROSAMINE; ETHYLNITROSOUREA; ETOPOSIDE; GLYCAN DERIVATIVE; HYDROXYUREA; MELAMINE; MELPHALAN; MESYLIC ACID ETHYL ESTER; METHYLNITROSOUREA; N (2 FLUORENYL)ACETAMIDE; PARACETAMOL; PROPANESULTONE; PYRENE; TEMOZOLOMIDE; THIOTEPA; UNCLASSIFIED DRUG; URETHAN; X LINKED PHOSPHATIDYLINOSITOL GLYCAN CLASS A; ZIDOVUDINE; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL GLYCAN-CLASS A PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CELL ASSAY; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROPOIESIS; GENE FREQUENCY; GENE MUTATION; GENOTOXICITY; GENOTOXICITY ASSAY; IN VIVO STUDY; MALE; MUTAGENICITY; NONHUMAN; PIGRET ASSAY; PRIORITY JOURNAL; RAT; RELIABILITY; RETICULOCYTE; DRUG EFFECTS; GENETICS; HUMAN; LABORATORY; MUTAGEN TESTING; MUTATION; ORGANIZATION AND MANAGEMENT; PROCEDURES; PUBLIC RELATIONS; REPRODUCIBILITY;

ERYTHROCYTES; ETHYLNITROSOUREA; HUMANS; INTERINSTITUTIONAL RELATIONS; LABORATORIES; MEMBRANE PROTEINS; MUTAGENICITY TESTS; MUTATION; REPRODUCIBILITY OF RESULTS; RETICULOCYTES;

EID: 85000893385     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2016.10.003     Document Type: Article

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