-
1
-
-
33745178831
-
Comparative overview of current international strategies and guidelines for genetic toxicology testing for regulatory purposes
-
Cimino MC. Comparative overview of current international strategies and guidelines for genetic toxicology testing for regulatory purposes. Environ Mol Mutagen. 2006; 47: 362-90.
-
(2006)
Environ Mol Mutagen.
, vol.47
, pp. 362-390
-
-
Cimino, M.C.1
-
2
-
-
0035012857
-
A review of the genotoxicity of marketed pharmaceuticals
-
Snyder RD, Green JW. A review of the genotoxicity of marketed pharmaceuticals. Mutat Res. 2001; 488: 151-69.
-
(2001)
Mutat Res.
, vol.488
, pp. 151-169
-
-
Snyder, R.D.1
Green, J.W.2
-
3
-
-
21544473568
-
Evaluation of the ability of battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity
-
Kirkland D, Aardema M, Henderson L., Muller L. Evaluation of the ability of battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity. Mutat Res. 2005; 584: 1-256.
-
(2005)
Mutat Res.
, vol.584
, pp. 1-256
-
-
Kirkland, D.1
Aardema, M.2
Henderson, L.3
Muller, L.4
-
4
-
-
0028046590
-
Molecular cloning of murine Pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function, and genetic locus
-
Kawagoe K, Takeda J, Endo Y, Kinoshita T. Molecular cloning of murine Pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function, and genetic locus. Genomics. 1994; 23: 566-74.
-
(1994)
Genomics
, vol.23
, pp. 566-574
-
-
Kawagoe, K.1
Takeda, J.2
Endo, Y.3
Kinoshita, T.4
-
5
-
-
0032481318
-
The first step of glycosyl-phosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1
-
Watanabe R, Inoue N, Westfall B, Taron CH, Orlean P, Takeda J, et al. The first step of glycosyl-phosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1. EMBO J. 1998; 17: 877-85.
-
(1998)
EMBO J.
, vol.17
, pp. 877-885
-
-
Watanabe, R.1
Inoue, N.2
Westfall, B.3
Taron, C.H.4
Orlean, P.5
Takeda, J.6
-
6
-
-
0032710713
-
Paroxysmal nocturnal hemoglobinuria: An acquired genetic disease
-
Nishimura J, Murakami Y, Kinoshita T. Paroxysmal nocturnal hemoglobinuria: An acquired genetic disease. Am J Hematol. 1999; 62: 175-82.
-
(1999)
Am J Hematol.
, vol.62
, pp. 175-182
-
-
Nishimura, J.1
Murakami, Y.2
Kinoshita, T.3
-
7
-
-
33747647412
-
PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesis
-
Brodsky RA, Hu R. PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesis. Leuk Lymphoma. 2006; 47: 1215-21.
-
(2006)
Leuk Lymphoma.
, vol.47
, pp. 1215-1221
-
-
Brodsky, R.A.1
Hu, R.2
-
8
-
-
0024316809
-
The glycosyl-phosphatidylinositol anchor of membrane proteins
-
Low MG. The glycosyl-phosphatidylinositol anchor of membrane proteins. Biochim Biophys Acta. 1989; 988: 427-54.
-
(1989)
Biochim Biophys Acta
, vol.988
, pp. 427-454
-
-
Low, M.G.1
-
9
-
-
0025203675
-
Glycolipid anchoring of plasma membrane proteins
-
Cross GA. Glycolipid anchoring of plasma membrane proteins. Annu Rev Cell Biol. 1990; 6: 1-39.
-
(1990)
Annu Rev Cell Biol.
, vol.6
, pp. 1-39
-
-
Cross, G.A.1
-
10
-
-
62149100368
-
Silencing of genes required for glycosyl-phosphatidylinositol anchor biosynthesis in burkitt lymphoma
-
Hu R, Mukhina GL, Lee SH, Jones RJ, Englund PT, Brown P, et al. Silencing of genes required for glycosyl-phosphatidylinositol anchor biosynthesis in Burkitt lymphoma. Exp Hematol. 2009; 37: 423-34.
-
(2009)
Exp Hematol.
, vol.37
, pp. 423-434
-
-
Hu, R.1
Mukhina, G.L.2
Lee, S.H.3
Jones, R.J.4
Englund, P.T.5
Brown, P.6
-
11
-
-
0027310539
-
Deficiency of the GPI anchor caused by somatic mutation of PIG-A gene in paroxysmal nocturnal hemoglobinuria
-
Takeda J, Miyata T, Kawagoe K, Iida Y, Endo Y, Fujita T, et al. Deficiency of the GPI anchor caused by somatic mutation of PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell. 1993; 72: 703-11.
-
(1993)
Cell
, vol.72
, pp. 703-711
-
-
Takeda, J.1
Miyata, T.2
Kawagoe, K.3
Iida, Y.4
Endo, Y.5
Fujita, T.6
-
12
-
-
0029981029
-
The use of monoclonal antibodies and flow cytometry in the diagnosis of paroxysmal nocturnal hemoglobinuria
-
Hall SE, Rosse WF. The use of monoclonal antibodies and flow cytometry in the diagnosis of paroxysmal nocturnal hemoglobinuria. Blood. 1996; 87: 5332-40.
-
(1996)
Blood
, vol.87
, pp. 5332-5340
-
-
Hall, S.E.1
Rosse, W.F.2
-
13
-
-
0033609114
-
Clonal population of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individual
-
Araten DJ, Nafa K, Pakdeesuwan K, Luzzatto L. Clonal population of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individual. Proc Natl Acad Sci USA. 1999; 96: 5209-14.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5209-5214
-
-
Araten, D.J.1
Nafa, K.2
Pakdeesuwan, K.3
Luzzatto, L.4
-
14
-
-
54249128207
-
Development of an in vivo gene mutation assay using the endogenous Pig-a gene: I. Flow cytometic detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat
-
Miura D, Dobrovolsky VN, Kasahara Y, Katsuura Y, Heflich RH. Development of an in vivo gene mutation assay using the endogenous Pig-A gene: I. Flow cytometic detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat. Environ Mol Mutagen. 2008; 49: 614-21.
-
(2008)
Environ Mol Mutagen.
, vol.49
, pp. 614-621
-
-
Miura, D.1
Dobrovolsky, V.N.2
Kasahara, Y.3
Katsuura, Y.4
Heflich, R.H.5
-
15
-
-
42949122947
-
In vivo mutation assay based on the endogenous Pig-a locus
-
Bryce S, Bemis J, Dertinger S. In vivo mutation assay based on the endogenous Pig-a locus. Environ Mol Mutagen. 2008; 49: 256-64.
-
(2008)
Environ Mol Mutagen.
, vol.49
, pp. 256-264
-
-
Bryce, S.1
Bemis, J.2
Dertinger, S.3
-
16
-
-
79957842103
-
Manifestation of Pig-a mutant bone marrow erythroids and peripheral blood erythrocytes in mice treated with N-ethyl-N-nitrosourea: Direct sequencing of Pig-a cDNA from bone marrow cells negative for GPI-anchored protein expression
-
Kimoto T, Suzuki K, Kobayashi XM, Dobrovolsky VN, Heflich RH, Miura D, et al. Manifestation of Pig-a mutant bone marrow erythroids and peripheral blood erythrocytes in mice treated with N-ethyl-N-nitrosourea: direct sequencing of Pig-a cDNA from bone marrow cells negative for GPI-anchored protein expression. Mutat Res. 2011; 723: 36-42.
-
(2011)
Mutat Res.
, vol.723
, pp. 36-42
-
-
Kimoto, T.1
Suzuki, K.2
Kobayashi, X.M.3
Dobrovolsky, V.N.4
Heflich, R.H.5
Miura, D.6
-
17
-
-
80155214466
-
Further development of the rat piga mutation assay: Measuring rat Pig-a mutant bone marrow erythroids and a high throughput assay for mutant peripheral blood reticulocytes
-
Kimoto T, Chikura S, Suzuki K, Kobayashi XM, Itano Y, Horibata K, et al. Further development of the rat Piga mutation assay: measuring rat Pig-a mutant bone marrow erythroids and a high throughput assay for mutant peripheral blood reticulocytes. Environ Mol Mutagen. 2011; 52: 774-83.
-
(2011)
Environ Mol Mutagen.
, vol.52
, pp. 774-783
-
-
Kimoto, T.1
Chikura, S.2
Suzuki, K.3
Kobayashi, X.M.4
Itano, Y.5
Horibata, K.6
-
18
-
-
54249134721
-
Development of an in vivo gene mutation assay using the endogenous Pig-a gene; II. Selection of Pig-a mutant rat spleen T-cells with proaerolysin and sequencing Pig-a cDNA from the mutants
-
Miura D, Dobrovolsky VN, Mittelstaedt RA, Kasahara Y, Katsuura Y, Heflich RH. Development of an in vivo gene mutation assay using the endogenous Pig-A gene; II. Selection of Pig-A mutant rat spleen T-cells with Proaerolysin and sequencing Pig-A cDNA from the mutants. Environ Mol Mutagen. 2008; 49: 622-30.
-
(2008)
Environ Mol Mutagen.
, vol.49
, pp. 622-630
-
-
Miura, D.1
Dobrovolsky, V.N.2
Mittelstaedt, R.A.3
Kasahara, Y.4
Katsuura, Y.5
Heflich, R.H.6
-
20
-
-
0033105696
-
Resistance of paroxysmal nocturnal hemoglobinuria cells to the glycosylphospha-tidylinositol-binding toxin aerolysin
-
Brodsky RA, Mukhina GL, Nelson KL, Lawrence RS, Jones RJ, Buckley JT. Resistance of paroxysmal nocturnal hemoglobinuria cells to the glycosylphospha-tidylinositol-binding toxin aerolysin. Blood. 1999; 93: 1749-56.
-
(1999)
Blood
, vol.93
, pp. 1749-1756
-
-
Brodsky, R.A.1
Mukhina, G.L.2
Nelson, K.L.3
Lawrence, R.S.4
Jones, R.J.5
Buckley, J.T.6
-
21
-
-
79957891346
-
Analysis of mutations in the Pig-a gene of spleen T-cell from N-ethyl-N-nitrosourea-treated fisher 344 rats
-
Miura D, Shaddock JG, Mittelstaedt RA, Dobrovolsky VN, Kimoto T, Kasahara Y, et al. Analysis of mutations in the Pig-a gene of spleen T-cell from N-ethyl-N-nitrosourea-treated Fisher 344 rats. Environ Mol Mutagen. 2011; 52: 419-23.
-
(2011)
Environ Mol Mutagen.
, vol.52
, pp. 419-423
-
-
Miura, D.1
Shaddock, J.G.2
Mittelstaedt, R.A.3
Dobrovolsky, V.N.4
Kimoto, T.5
Kasahara, Y.6
-
22
-
-
77951556618
-
Pig-a mutation: Kinetics in rat erythrocytes following exposure to five prototypical mutagens
-
Phonethepswath S, Franklin D, Torous DK, Bryce SM, Bemis JC, Raja S, et al. Pig-a mutation: Kinetics in rat erythrocytes following exposure to five prototypical mutagens. Toxicol Sci. 2010; 114: 59-70.
-
(2010)
Toxicol Sci.
, vol.114
, pp. 59-70
-
-
Phonethepswath, S.1
Franklin, D.2
Torous, D.K.3
Bryce, S.M.4
Bemis, J.C.5
Raja, S.6
-
25
-
-
67650021207
-
Accumulation and persistence of Pig-a mutant peripheral red blood cells following treatment of rats with single and split doses of N-ethyl-N-nitrosourea
-
Miura D, Dobrovolsky VN, Kimoto T, Kasahara Y, Heflich RH. Accumulation and persistence of Pig-A mutant peripheral red blood cells following treatment of rats with single and split doses of N-ethyl-N-nitrosourea. Mutat Res. 2009; 677: 86-92.
-
(2009)
Mutat Res.
, vol.677
, pp. 86-92
-
-
Miura, D.1
Dobrovolsky, V.N.2
Kimoto, T.3
Kasahara, Y.4
Heflich, R.H.5
-
26
-
-
0141785156
-
In vivo transgenic mutation assays
-
Thybaud V, Dean S, Nohmi T, de Boer J, Douglas GR, Glickman BW, et al. In vivo transgenic mutation assays. Mutat Res. 2003; 540: 141-51.
-
(2003)
Mutat Res.
, vol.540
, pp. 141-151
-
-
Thybaud, V.1
Dean, S.2
Nohmi, T.3
De Boer, J.4
Douglas, G.R.5
Glickman, B.W.6
-
27
-
-
0033594885
-
X inactivation and somatic cell selection rescue female mice carrying a piga-null mutation
-
Keller P, Tremml G, Rosti V, Bessler M. X inactivation and somatic cell selection rescue female mice carrying a Piga-null mutation. Proc Natl Acad Sci USA. 1999; 96: 7479-83.
-
(1999)
Proc Natl Acad Sci USA.
, vol.96
, pp. 7479-7483
-
-
Keller, P.1
Tremml, G.2
Rosti, V.3
Bessler, M.4
-
28
-
-
0036291105
-
Murine models of paroxysmal nocturnal hemoglobinuria
-
Rosti V. Murine models of paroxysmal nocturnal hemoglobinuria. Ann N Y Acad Sci. 2002; 963: 290-6.
-
(2002)
Ann N y Acad Sci.
, vol.963
, pp. 290-296
-
-
Rosti, V.1
-
29
-
-
80155153686
-
International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories
-
Dertinger SD, Phonethepswath S, Weller P, Nicolette J, Murray J, Sonders P, et al. International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories. Environ Mol Mutagen. 2011; 52: 690-8.
-
(2011)
Environ Mol Mutagen.
, vol.52
, pp. 690-698
-
-
Dertinger, S.D.1
Phonethepswath, S.2
Weller, P.3
Nicolette, J.4
Murray, J.5
Sonders, P.6
-
30
-
-
80155183489
-
International Pig-a gene mutation assay trial (Stage III): Results with N-methyl-N-nitrosourea
-
Lynch AM, Giddings A, Custer L, Gleason C, Henwood A, Aylott M, et al. International Pig-a gene mutation assay trial (Stage III): Results with N-methyl-N-nitrosourea. Environ Mol Mutagen. 2011; 52: 699-710.
-
(2011)
Environ Mol Mutagen.
, vol.52
, pp. 699-710
-
-
Lynch, A.M.1
Giddings, A.2
Custer, L.3
Gleason, C.4
Henwood, A.5
Aylott, M.6
-
31
-
-
80155163022
-
Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethylnitrosamine in the pig - A, micronucleus and comet assays integrated in 28-day repeat dose studies
-
Shi J, Krsmanovic L, Bruce S, Kelly T, Paranjpe M, Szabo K, et al. Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethylnitrosamine in the Pig-a, micronucleus and Comet assays integrated in 28-day repeat dose studies. Environ Mol Mutagen. 2011; 52: 711-20.
-
(2011)
Environ Mol Mutagen.
, vol.52
, pp. 711-720
-
-
Shi, J.1
Krsmanovic, L.2
Bruce, S.3
Kelly, T.4
Paranjpe, M.5
Szabo, K.6
-
32
-
-
80155154443
-
Report on stage III Pig-a mutation assays using N-ethyl-N-nitrosourea-comparison with other in vivo genotoxicity endpoints
-
Cammerer Z, Bhalli JA, Cao X, Coffing SL, Dickinson D, Dobo KL, et al. Report on Stage III Pig-a mutation assays using N-ethyl-N-nitrosourea-Comparison with other in vivo genotoxicity endpoints, Environ Mol Mutagen. 2011; 52: 721-30.
-
(2011)
Environ Mol Mutagen.
, vol.52
, pp. 721-730
-
-
Cammerer, Z.1
Bhalli, J.A.2
Cao, X.3
Coffing, S.L.4
Dickinson, D.5
Dobo, K.L.6
-
33
-
-
80155189057
-
Report on stage III Pig-a mutation assays using benzo[a]pyrene
-
Bhalli JA, Shaddock JG, Pearce MG, Dobrovolsky VN, Cao X, Heflich RH, et al. Report on Stage III Pig-a mutation assays using benzo[a]pyrene. Environ Mol Mutagen. 2011; 52: 731-7.
-
(2011)
Environ Mol Mutagen.
, vol.52
, pp. 731-737
-
-
Bhalli, J.A.1
Shaddock, J.G.2
Pearce, M.G.3
Dobrovolsky, V.N.4
Cao, X.5
Heflich, R.H.6
-
34
-
-
80155189083
-
Integration of pig - A, micronucleus, chromosome aberration, and comet assay endpoints in a 28-day rodent toxicity study with 4-nitro-quinoline-1-oxide
-
Stankowski Jr. LF, Roberts DJ, Chen H, Lawlor T, McKeon M, Murli H, et al. Integration of Pig-a, micronucleus, chromosome aberration, and Comet assay endpoints in a 28-day rodent toxicity study with 4-nitro-quinoline-1-oxide. Environ Mol Mutagen. 2011; 52: 738-47.
-
(2011)
Environ Mol Mutagen.
, vol.52
, pp. 738-747
-
-
Stankowski, L.F.1
Roberts, D.J.2
Chen, H.3
Lawlor, T.4
McKeon, M.5
Murli, H.6
-
35
-
-
80155178419
-
Interlaboratory Pig-a gene mutation assay trial: Studies of 1,3-propane sultone with immunomagnetic enrichment of mutant erythrocytes
-
Dertinger SD, Phonethepswath S, Weller P, Avlasevich S, Torous DK, Mereness JA, et al. Interlaboratory Pig-a gene mutation assay trial: Studies of 1,3-propane sultone with immunomagnetic enrichment of mutant erythrocytes. Environ Mol Mutagen. 2011; 52: 748-55.
-
(2011)
Environ Mol Mutagen.
, vol.52
, pp. 748-755
-
-
Dertinger, S.D.1
Phonethepswath, S.2
Weller, P.3
Avlasevich, S.4
Torous, D.K.5
Mereness, J.A.6
-
36
-
-
84881030430
-
Interlaboratory trial of the rat Pig-a mutation assay using an erythroid marker HIS49 antibody
-
Kimoto T, Horibata K, Chikura S, Hashimoto K, Itoh S, Sanada H, et al. Interlaboratory trial of the rat Pig-a mutation assay using an erythroid marker HIS49 antibody. Mutat Res. 2013; 755 126-34.
-
(2013)
Mutat Res.
, vol.755
, pp. 126-134
-
-
Kimoto, T.1
Horibata, K.2
Chikura, S.3
Hashimoto, K.4
Itoh, S.5
Sanada, H.6
-
37
-
-
0029417250
-
Analysis of in vivo mutation induced by N-ethyl-N-nitrosourea in the hprt gene of rat lymphocytes
-
Mittelstaedt RA, Smith BA, Heflich RH. Analysis of in vivo mutation induced by N-ethyl-N-nitrosourea in the hprt gene of rat lymphocytes. Environ Mol Mutagen. 1995; 26: 261-9.
-
(1995)
Environ Mol Mutagen.
, vol.26
, pp. 261-269
-
-
Mittelstaedt, R.A.1
Smith, B.A.2
Heflich, R.H.3
|