-
1
-
-
78349292149
-
The in vivo Pig-a gene mutation assay, a potential tool for regulatory safety assessment
-
Dobrovolsky VN, Miura D, Heflich RH, Dertinger SD. The in vivo Pig-a gene mutation assay, a potential tool for regulatory safety assessment. Environ Mol Mutagen. 2010; 51: 825-35.
-
(2010)
Environ Mol Mutagen.
, vol.51
, pp. 825-835
-
-
Dobrovolsky, V.N.1
Miura, D.2
Heflich, R.H.3
Dertinger, S.D.4
-
3
-
-
54249128207
-
Development of an in vivo gene mutation assay using the endogenous Pig-a gene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat
-
Miura D, Dobrovolsky VN, Kasahara Y, Katsuura Y, Heflich RH. Development of an in vivo gene mutation assay using the endogenous Pig-A gene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat. Environ Mol Mutagen. 2008; 49: 614-21.
-
(2008)
Environ Mol Mutagen.
, vol.49
, pp. 614-621
-
-
Miura, D.1
Dobrovolsky, V.N.2
Kasahara, Y.3
Katsuura, Y.4
Heflich, R.H.5
-
4
-
-
54249134721
-
Development of an in vivo gene mutation assay using the endogenous Pig-a gene: II. Selection of Pig-a mutant rat spleen T-cells with proaerolysin and sequencing Pig-a cDNA from the mutants
-
Miura D, Dobrovolsky VN, Mittelstaedt RA, Kasahara Y, Katsuura Y, Heflich RH. Development of an in vivo gene mutation assay using the endogenous Pig-A gene: II. Selection of Pig-A mutant rat spleen T-cells with proaerolysin and sequencing Pig-A cDNA from the mutants. Environ Mol Mutagen. 2008; 49: 622-30.
-
(2008)
Environ Mol Mutagen.
, vol.49
, pp. 622-630
-
-
Miura, D.1
Dobrovolsky, V.N.2
Mittelstaedt, R.A.3
Kasahara, Y.4
Katsuura, Y.5
Heflich, R.H.6
-
5
-
-
80155178417
-
Need and potential value of the Pig-a in vivo mutation assay - A HESI perspective
-
Schuler M, Gollapudi BB, Thybaud V, Kim JH. Need and potential value of the Pig-a in vivo mutation assay - A HESI perspective, Environ Mol Mutagen. 2011; 52: 685-9.
-
(2011)
Environ Mol Mutagen.
, vol.52
, pp. 685-689
-
-
Schuler, M.1
Gollapudi, B.B.2
Thybaud, V.3
Kim, J.H.4
-
6
-
-
84869753046
-
Efficient monitoring of in vivo Pig-a gene mutation and chromosomal damage: Summary of 7 published studies and results from 11 new reference compounds
-
Dertinger SD, Phonethepswath S, Avlasevich S, Torous DK, Mereness J, Bryce SM, et al. Efficient monitoring of in vivo Pig-a gene mutation and chromosomal damage: Summary of 7 published studies and results from 11 new reference compounds, Toxicol Sci. 2012; 130: 328-48.
-
(2012)
Toxicol Sci.
, vol.130
, pp. 328-348
-
-
Dertinger, S.D.1
Phonethepswath, S.2
Avlasevich, S.3
Torous, D.K.4
Mereness, J.5
Bryce, S.M.6
-
7
-
-
77249096480
-
Flow cytometric detection of Pig-a mutant red blood cells using an erythroid-specific antibody: Application of the method for evaluating the in vivo genotoxicity of methylpheni-date in adolescent rats
-
Dobrovolsky VN, Boctor SY, Twaddle NC, Doerge DR, Bishop ME, Manjanatha MG, et al. Flow cytometric detection of Pig-A mutant red blood cells using an erythroid-specific antibody: application of the method for evaluating the in vivo genotoxicity of methylpheni-date in adolescent rats, Environ Mol Mutagen. 2010; 51: 138-45.
-
(2010)
Environ Mol Mutagen.
, vol.51
, pp. 138-145
-
-
Dobrovolsky, V.N.1
Boctor, S.Y.2
Twaddle, N.C.3
Doerge, D.R.4
Bishop, M.E.5
Manjanatha, M.G.6
-
8
-
-
0028046590
-
Molecular cloning of murine Pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function, and genetic locus
-
Kawagoe K, Takeda J, Endo Y, Kinoshita T. Molecular cloning of murine Pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function, and genetic locus. Genomics. 1994; 23: 566-74.
-
(1994)
Genomics
, vol.23
, pp. 566-574
-
-
Kawagoe, K.1
Takeda, J.2
Endo, Y.3
Kinoshita, T.4
-
9
-
-
0035801698
-
FES-cre targets phosphatidylinositol glycan class A (PIGA) inactivation to hematopoietic stem cells in the bone marrow
-
Keller P, Payne JL, Tremml G, Greer PA, Gaboli M, Pandolfi PP, et al. FES-Cre targets phosphatidylinositol glycan class A (PIGA) inactivation to hematopoietic stem cells in the bone marrow. J Exp Med. 2001; 194: 581-9.
-
(2001)
J Exp Med.
, vol.194
, pp. 581-589
-
-
Keller, P.1
Payne, J.L.2
Tremml, G.3
Greer, P.A.4
Gaboli, M.5
Pandolfi, P.P.6
-
10
-
-
56249145977
-
Erythrocyte-based Pig-a gene mutation assay: Demonstration of cross-species potential
-
Phonethepswath S, Bryce SM, Bemis JC, Dertinger SD. Erythrocyte-based Pig-a gene mutation assay: demonstration of cross-species potential. Mutat Res. 2008; 657: 122-6.
-
(2008)
Mutat Res.
, vol.657
, pp. 122-126
-
-
Phonethepswath, S.1
Bryce, S.M.2
Bemis, J.C.3
Dertinger, S.D.4
-
11
-
-
79957891346
-
Analysis of mutations in the Pig-a gene of spleen T-cells from N-ethyl-N-nitrosourea-treated fisher 344 rats
-
Miura D, Shaddock, JG, Mittelstaedt, RA, Dobrovolsky, VN, Kimoto, T, Kasahara Y, et al. Analysis of mutations in the Pig-a gene of spleen T-cells from N-ethyl-N-nitrosourea-treated Fisher 344 rats. Environ Mol Mutagen. 2011; 52: 419-23.
-
(2011)
Environ Mol Mutagen.
, vol.52
, pp. 419-423
-
-
Miura, D.1
Shaddock, J.G.2
Mittelstaedt, R.A.3
Dobrovolsky, V.N.4
Kimoto, T.5
Kasahara, Y.6
-
12
-
-
67650021207
-
Accumulation and persistence of Pig-a mutant peripheral red blood cells following treatment of rats with single and split doses of N-ethyl-N-nitrosourea
-
Miura D, Dobrovolsky VN, Kimoto T, Kasahara Y, Heflich RH. Accumulation and persistence of Pig-A mutant peripheral red blood cells following treatment of rats with single and split doses of N-ethyl-N-nitrosourea. Mutat Res. 2009; 677: 86-92.
-
(2009)
Mutat Res.
, vol.677
, pp. 86-92
-
-
Miura, D.1
Dobrovolsky, V.N.2
Kimoto, T.3
Kasahara, Y.4
Heflich, R.H.5
-
13
-
-
77954067514
-
Integration of mutation and chromosomal damage endpoints into 28-day repeated dose toxicology studies
-
Dertinger SD, Phonethepswath S, Franklin D, Weller P, Torous DK, Bryce SM, et al. Integration of mutation and chromosomal damage endpoints into 28-day repeated dose toxicology studies. Toxicol Sci. 2010; 115: 401-11.
-
(2010)
Toxicol Sci.
, vol.115
, pp. 401-411
-
-
Dertinger, S.D.1
Phonethepswath, S.2
Franklin, D.3
Weller, P.4
Torous, D.K.5
Bryce, S.M.6
-
14
-
-
84881030430
-
Interlaboratory trial of the rat Pig-a mutation assay using an erythroid marker HIS49 antibody
-
Kimoto T, Horibata K, Chikura S, Hashimoto K, Itoh S, Sanada H, et al. Interlaboratory trial of the rat Pig-a mutation assay using an erythroid marker HIS49 antibody. Mutat Res. 2013; 755: 126-34.
-
(2013)
Mutat Res.
, vol.755
, pp. 126-134
-
-
Kimoto, T.1
Horibata, K.2
Chikura, S.3
Hashimoto, K.4
Itoh, S.5
Sanada, H.6
-
15
-
-
84918783072
-
-
Document of Food and Drug Administration. Revised April 2012
-
Cyclophosphamide for Injection, USP/Cyclophosphamide Tablets, USP. Document of Food and Drug Administration. Revised April 2012. http://www.accessdata. fda.gov/drugsatfdadocs/label/2012/012141s089lbl.pdf
-
Cyclophosphamide for Injection, USP/Cyclophosphamide Tablets, USP
-
-
-
16
-
-
84881023095
-
Sensitivity of the Pig-a assay for detecting gene mutation in rats exposed acutely to strong clastogens
-
Bhalli JA, Shaddock JG, Pearce MG, Dobrovolsky VN. Sensitivity of the Pig-a assay for detecting gene mutation in rats exposed acutely to strong clastogens. Mutagenesis. 2013; 28: 447-55.
-
(2013)
Mutagenesis
, vol.28
, pp. 447-455
-
-
Bhalli, J.A.1
Shaddock, J.G.2
Pearce, M.G.3
Dobrovolsky, V.N.4
-
17
-
-
2542566599
-
Hprt mutant frequencies in splenic T-cells of male F344 rats exposed by inhalation to propylene
-
Walker DM, Seilkop SK, Scott BR, Walker VE. Hprt mutant frequencies in splenic T-cells of male F344 rats exposed by inhalation to propylene. Environ Mol Mutagen. 2004; 43: 265-72.
-
(2004)
Environ Mol Mutagen.
, vol.43
, pp. 265-272
-
-
Walker, D.M.1
Seilkop, S.K.2
Scott, B.R.3
Walker, V.E.4
-
18
-
-
84867875271
-
Effective use of the Pig-a gene mutation assay for mutagenicity screening: Measuring CD59-deficient red blood cells in rats treated with genotoxic chemicals
-
Kimoto T, Chikura S, Suzuki K, Kobayashi XM, Itano Y, Miura D, et al. Effective use of the Pig-a gene mutation assay for mutagenicity screening: measuring CD59-deficient red blood cells in rats treated with genotoxic chemicals. J Toxicol Sci. 2012; 37: 943-55.
-
(2012)
J Toxicol Sci.
, vol.37
, pp. 943-955
-
-
Kimoto, T.1
Chikura, S.2
Suzuki, K.3
Kobayashi, X.M.4
Itano, Y.5
Miura, D.6
|