Evaluation of red blood cell Pig-a assay and PIGRET assay in rats using chlorambucil

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 811, Issue , 2016, Pages 91-96

  Maeda, Akihisa ^a   Takahashi, Kei ^a   Tsuchiyama, Hiromi ^a   Oshida, Keiyu ^a  

^a TORAY INDUSTRIES INC   (Japan)

Author keywords

Chlorambucil; Pig a assay; PIGRET assay; Rat; Single dose

Indexed keywords

CHLORAMBUCIL; MEMBRANE PROTEIN; MUTAGENIC AGENT; PHOSPHATIDYLINOSITOL GLYCAN-CLASS A PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CLINICAL EVALUATION; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DRUG DOSE INCREASE; DRUG MEGADOSE; ERYTHROCYTE; ERYTHROCYTE COUNT; GENOTOXICITY; GENOTOXICITY ASSAY; INTERMETHOD COMPARISON; LD50; LOW DRUG DOSE; MALE; MUTAGEN TESTING; MUTAGENICITY; MUTANT; MUTATION RATE; NONHUMAN; PIG A ASSAY; PIGRET ASSAY; PRIORITY JOURNAL; RAT; REPEATED DRUG DOSE; RETICULOCYTE; SINGLE DRUG DOSE; ANIMAL; DRUG EFFECTS; GENETICS; PROCEDURES; SPRAGUE DAWLEY RAT;

ANIMALS; CHLORAMBUCIL; ERYTHROCYTES; MALE; MEMBRANE PROTEINS; MUTAGENICITY TESTS; MUTAGENS; RATS; RATS, SPRAGUE-DAWLEY; RETICULOCYTES;

EID: 84953455295     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2015.12.006     Document Type: Article

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