Report on the rat Pig-a assay using an anti-rat erythroid marker HIS49 antibody in a single dose study of 1,2-dimethylhydrazine

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 811, Issue , 2016, Pages 21-28

  Chikura, Satsuki ^a   Okada, Yuki ^a   Kimoto, Takafumi ^a   Kaneko, Hideshi ^a   Miura, Daishiro ^a   Kasahara, Yoshinori ^a  

^a TEIJIN PHARMA LIMITED   (Japan)

Author keywords

Comet assay; Flow cytometry; Micronucleus test; Pig a assay

Indexed keywords

1,2 DIMETHYLHYDRAZINE; ANTIBODY; DNA; HIS49 ANTIBODY; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL GLYCAN-CLASS A PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BONE MARROW TOXICITY; CLINICAL EVALUATION; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; ERYTHROCYTE; FLOW CYTOMETRY; FOLLOW UP; GENOTOXICITY; HEDGEHOG; IN VIVO STUDY; LIVER; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RETICULOCYTE; SINGLE DRUG DOSE; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; MUTAGEN TESTING; PROCEDURES; SPRAGUE DAWLEY RAT;

1,2-DIMETHYLHYDRAZINE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; MALE; MEMBRANE PROTEINS; MUTAGENICITY TESTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84992426925     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2016.02.008     Document Type: Article

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