메뉴 건너뛰기




Volumn 31, Issue 6, 2016, Pages 617-626

Differential genotoxicity of acrylamide in the micronucleus and Pig - A gene mutation assays in F344 rats and B6C3F1 mice

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLAMIDE; DNA; DRINKING WATER; ETHYLNITROSOUREA; GLYCIDAMIDE; MUTANT PROTEIN; PIG A PROTEIN; UNCLASSIFIED DRUG;

EID: 84994476891     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gew028     Document Type: Article
Times cited : (25)

References (65)
  • 3
    • 85052875135 scopus 로고    scopus 로고
    • Scientifc Opinion on acrylamide in food. European Food Safety Authority (EFSA), Parma, Italy
    • EFSA. (2015) Scientifc Opinion on acrylamide in food. European Food Safety Authority (EFSA), Parma, Italy. EFSA J., 13, 4104.
    • (2015) EFSA J. , vol.13 , pp. 4104
    • EFSA1
  • 4
    • 0031023980 scopus 로고    scopus 로고
    • Hemoglobin adducts of acrylamide and acrylonitrile in laboratory workers, smokers and nonsmokers
    • Bergmark, E. (1997) Hemoglobin adducts of acrylamide and acrylonitrile in laboratory workers, smokers and nonsmokers. Chem. Res. Toxicol., 10, 78-84.
    • (1997) Chem. Res. Toxicol. , vol.10 , pp. 78-84
    • Bergmark, E.1
  • 5
    • 20044389658 scopus 로고    scopus 로고
    • NTP-CERHR expert panel report on the reproductive and developmental toxicity of acrylamide
    • Manson, J., Brabec, M. J., Buelke-Sam, J., et al. (2005) NTP-CERHR expert panel report on the reproductive and developmental toxicity of acrylamide. Birth Defects Res. B Dev. Reprod. Toxicol. 74, 17-113.
    • (2005) Birth Defects Res. B Dev. Reprod. Toxicol. , vol.74 , pp. 17-113
    • Manson, J.1    Brabec, M.J.2    Buelke-Sam, J.3
  • 6
    • 0029738247 scopus 로고    scopus 로고
    • Two case reports of neurological disease in coal mine preparation plant workers
    • Mulloy, K. B. (1996) Two case reports of neurological disease in coal mine preparation plant workers. Am. J. Ind. Med., 30, 56-61.
    • (1996) Am. J. Ind. Med. , vol.30 , pp. 56-61
    • Mulloy, K.B.1
  • 8
    • 84927537648 scopus 로고    scopus 로고
    • Dietary acrylamide and cancer risk: An updated meta-analysis
    • Pelucchi, C., Bosetti, C., Galeone, C. and La Vecchia, C. (2015) Dietary acrylamide and cancer risk: an updated meta-analysis. Int. J. Cancer, 136, 2912-2922.
    • (2015) Int. J. Cancer , vol.136 , pp. 2912-2922
    • Pelucchi, C.1    Bosetti, C.2    Galeone, C.3    La Vecchia, C.4
  • 9
    • 84903271808 scopus 로고    scopus 로고
    • Dietary acrylamide and human cancer: A systematic review of literature
    • Virk-Baker, M. K., Nagy, T. R., Barnes, S. and Groopman, J. (2014) Dietary acrylamide and human cancer: a systematic review of literature. Nutr. Cancer, 66, 774-790.
    • (2014) Nutr. Cancer , vol.66 , pp. 774-790
    • Virk-Baker, M.K.1    Nagy, T.R.2    Barnes, S.3    Groopman, J.4
  • 10
    • 0041802954 scopus 로고    scopus 로고
    • Chemistry, biochemistry, and safety of acrylamide. A review
    • Friedman, M. (2003) Chemistry, biochemistry, and safety of acrylamide. A review. J. Agric. Food Chem., 51, 4504-4526.
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 4504-4526
    • Friedman, M.1
  • 11
    • 84994472060 scopus 로고    scopus 로고
    • Toxicological Review of Acrylamide (CAS No. 79-06-1)
    • EPA/635/R-07/009F. U.S. Environmental Protection Agency, Washington, DC
    • EPA. 2010. Toxicological Review of Acrylamide (CAS No. 79-06-1). In Support of Summary Information on the Integrated Risk Information System (IRIS). EPA/635/R-07/009F. U.S. Environmental Protection Agency, Washington, DC.
    • (2010) Support of Summary Information on the Integrated Risk Information System (IRIS)
    • EPA1
  • 12
    • 84867416800 scopus 로고    scopus 로고
    • Carcinogenicity of acrylamide in B6C3F(1) mice and F344/N rats from a 2-year drinking water exposure
    • Beland, F. A., Mellick, P. W., Olson, G. R., Mendoza, M. C., Marques, M. M. and Doerge, D. R. (2013) Carcinogenicity of acrylamide in B6C3F(1) mice and F344/N rats from a 2-year drinking water exposure. Food Chem. Toxicol., 51, 149-159.
    • (2013) Food Chem. Toxicol. , vol.51 , pp. 149-159
    • Beland, F.A.1    Mellick, P.W.2    Olson, G.R.3    Mendoza, M.C.4    Marques, M.M.5    Doerge, D.R.6
  • 13
    • 77957179358 scopus 로고
    • A lifetime onco-genicity study in rats with acrylamide
    • Friedman, M. A., Dulak, L. H. and Stedham, M. A. (1995) A lifetime onco-genicity study in rats with acrylamide. Fund. Appl. Toxicol., 27, 95-105.
    • (1995) Fund. Appl. Toxicol. , vol.27 , pp. 95-105
    • Friedman, M.A.1    Dulak, L.H.2    Stedham, M.A.3
  • 15
    • 84940166780 scopus 로고    scopus 로고
    • Two-year carcino-genicity study of acrylamide in Wistar Han rats with in utero exposure
    • Maronpot, R. R., Thoolen, R. J. and Hansen, B. (2015) Two-year carcino-genicity study of acrylamide in Wistar Han rats with in utero exposure. Exp. Toxicol. Pathol., 67, 189-195.
    • (2015) Exp. Toxicol. Pathol. , vol.67 , pp. 189-195
    • Maronpot, R.R.1    Thoolen, R.J.2    Hansen, B.3
  • 17
    • 0029123223 scopus 로고
    • Acrylamide: A review of its genotoxicity and an assessment of heritable genetic risk
    • Dearfeld, K. L., Douglas, G. R., Ehling, U. H., Moore, M. M., Sega, G. A. and Brusick, D. J. (1995) Acrylamide: a review of its genotoxicity and an assessment of heritable genetic risk. Mutat. Res., 330, 71-99.
    • (1995) Mutat. Res. , vol.330 , pp. 71-99
    • Dearfeld, K.L.1    Douglas, G.R.2    Ehling, U.H.3    Moore, M.M.4    Sega, G.A.5    Brusick, D.J.6
  • 18
    • 77956448685 scopus 로고    scopus 로고
    • Collaborative study on ffteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies
    • Rothfuss, A., O'Donovan, M., De Boeck, M., et al. (2010) Collaborative study on ffteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies. Mutat. Res., 702, 40-69.
    • (2010) Mutat. Res. , vol.702 , pp. 40-69
    • Rothfuss, A.1    O'Donovan, M.2    De Boeck, M.3
  • 19
    • 77951662689 scopus 로고    scopus 로고
    • Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol
    • Recio, L., Hobbs, C., Caspary, W. and Witt, K. L. (2010) Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol. J. Toxicol. Sci., 35, 149- 162.
    • (2010) J. Toxicol. Sci. , vol.35 , pp. 149-162
    • Recio, L.1    Hobbs, C.2    Caspary, W.3    Witt, K.L.4
  • 20
    • 36848999800 scopus 로고    scopus 로고
    • Comparison of fow cytometry- and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and genotoxic chemicals
    • Witt, K. L., Livanos, E., Kissling, G. E., Torous, D. K., Caspary, W., Tice, R. R. and Recio, L. (2008) Comparison of fow cytometry- and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and genotoxic chemicals. Mutat. Res., 649, 101-113.
    • (2008) Mutat. Res. , vol.649 , pp. 101-113
    • Witt, K.L.1    Livanos, E.2    Kissling, G.E.3    Torous, D.K.4    Caspary, W.5    Tice, R.R.6    Recio, L.7
  • 21
    • 58049211931 scopus 로고    scopus 로고
    • Investigation of the low-dose response in the in vivo induction of micronuclei and adducts by acrylamide
    • Zeiger, E., Recio, L., Fennell, T. R., Haseman, J. K., Snyder, R. W. and Friedman, M. (2009) Investigation of the low-dose response in the in vivo induction of micronuclei and adducts by acrylamide. Toxicol. Sci., 107, 247-257.
    • (2009) Toxicol. Sci. , vol.107 , pp. 247-257
    • Zeiger, E.1    Recio, L.2    Fennell, T.R.3    Haseman, J.K.4    Snyder, R.W.5    Friedman, M.6
  • 23
    • 0027465185 scopus 로고
    • Detection of chemical mutagens using Muta Mouse: A transgenic mouse model
    • Hoorn, A. J., Custer, L. L., Myhr, B. C., Brusick, D., Gossen, J. and Vijg, J. (1993) Detection of chemical mutagens using Muta Mouse: a transgenic mouse model. Mutagenesis, 8, 7-10.
    • (1993) Mutagenesis , vol.8 , pp. 7-10
    • Hoorn, A.J.1    Custer, L.L.2    Myhr, B.C.3    Brusick, D.4    Gossen, J.5    Vijg, J.6
  • 24
    • 0030949309 scopus 로고    scopus 로고
    • Somatic and germ cell mutagenesis in lambda lacZ transgenic mice treated with acrylamide or ethylnitrosourea
    • Krebs, O. and Favor, J. (1997) Somatic and germ cell mutagenesis in lambda lacZ transgenic mice treated with acrylamide or ethylnitrosourea. Mutat. Res., 388, 239-248.
    • (1997) Mutat. Res. , vol.388 , pp. 239-248
    • Krebs, O.1    Favor, J.2
  • 25
    • 84931047985 scopus 로고    scopus 로고
    • Acrylamide-induced carcinogenicity in mouse lung involves mutagenicity: CII gene mutations in the lung of big blue mice exposed to acrylamide and glycidamide for up to 4 weeks
    • Manjanatha, M. G., Guo, L. W., Shelton, S. D. and Doerge, D. R. (2015) Acrylamide-induced carcinogenicity in mouse lung involves mutagenicity: cII gene mutations in the lung of big blue mice exposed to acrylamide and glycidamide for up to 4 weeks. Environ. Mol. Mutagen., 56, 446-456.
    • (2015) Environ. Mol. Mutagen. , vol.56 , pp. 446-456
    • Manjanatha, M.G.1    Guo, L.W.2    Shelton, S.D.3    Doerge, D.R.4
  • 26
    • 77954055901 scopus 로고    scopus 로고
    • The genotoxicity of acrylamide and glycidamide in big blue rats
    • Mei, N., McDaniel, L. P., Dobrovolsky, V. N., Guo, X., et al. (2010) The genotoxicity of acrylamide and glycidamide in big blue rats. Toxicol. Sci., 115, 412-421.
    • (2010) Toxicol. Sci. , vol.115 , pp. 412-421
    • Mei, N.1    McDaniel, L.P.2    Dobrovolsky, V.N.3    Guo, X.4
  • 28
    • 0023239912 scopus 로고
    • Mutagenicity and clastogenicity of acrylamide in L5178Y mouse lymphoma cells
    • Moore, M. M., Amtower, A., Doerr, C., Brock, K. H. and Dearfeld, K. L. (1987) Mutagenicity and clastogenicity of acrylamide in L5178Y mouse lymphoma cells. Environ. Mutagen., 9, 261-267.
    • (1987) Environ. Mutagen. , vol.9 , pp. 261-267
    • Moore, M.M.1    Amtower, A.2    Doerr, C.3    Brock, K.H.4    Dearfeld, K.L.5
  • 29
    • 0025000669 scopus 로고
    • Acrylamide is metabolized to glycidamide in the rat: Evidence from hemoglobin adduct formation
    • Calleman, C. J., Bergmark, E. and Costa, L. G. (1990) Acrylamide is metabolized to glycidamide in the rat: evidence from hemoglobin adduct formation. Chem. Res. Toxicol., 3, 406-412.
    • (1990) Chem. Res. Toxicol. , vol.3 , pp. 406-412
    • Calleman, C.J.1    Bergmark, E.2    Costa, L.G.3
  • 32
    • 0034102569 scopus 로고    scopus 로고
    • 1-Aminobenzotriazole inhibits acrylamide-induced dominant lethal effects in spermatids of male mice
    • Adler, I. D., Baumgartner, A., Gonda, H., Friedman, M. A. and Skerhut, M. (2000) 1-Aminobenzotriazole inhibits acrylamide-induced dominant lethal effects in spermatids of male mice. Mutagenesis, 15, 133-136.
    • (2000) Mutagenesis , vol.15 , pp. 133-136
    • Adler, I.D.1    Baumgartner, A.2    Gonda, H.3    Friedman, M.A.4    Skerhut, M.5
  • 34
    • 20444379609 scopus 로고    scopus 로고
    • Genotoxicity and toxicological effects of acrylamide on reproductive system in male rats
    • Yang, H. J., Lee, S. H., Jin, Y., Choi, J. H., Han, C. H. and Lee, M. H. (2005) Genotoxicity and toxicological effects of acrylamide on reproductive system in male rats. J. Vet. Sci., 6, 103-109.
    • (2005) J. Vet. Sci. , vol.6 , pp. 103-109
    • Yang, H.J.1    Lee, S.H.2    Jin, Y.3    Choi, J.H.4    Han, C.H.5    Lee, M.H.6
  • 36
    • 11844263934 scopus 로고    scopus 로고
    • Dose-response modeling of in vivo genotoxicity data for use in risk assessment: Some approaches illustrated by an analysis of acrylamide
    • Allen, B., Zeiger, E., Lawrence, G., Friedman, M. and Shipp, A. (2005) Dose-response modeling of in vivo genotoxicity data for use in risk assessment: some approaches illustrated by an analysis of acrylamide. Regul. Toxicol. Pharmacol., 41, 6-27.
    • (2005) Regul. Toxicol. Pharmacol. , vol.41 , pp. 6-27
    • Allen, B.1    Zeiger, E.2    Lawrence, G.3    Friedman, M.4    Shipp, A.5
  • 37
    • 84928810972 scopus 로고    scopus 로고
    • The in vivo Pig - A assay: A report of the International Workshop on Genotoxicity Testing (IWGT) Workgroup
    • Gollapudi, B. B., Lynch, A. M., Hefich, R. H., et al. (2015) The in vivo Pig - A assay: A report of the International Workshop On Genotoxicity Testing (IWGT) Workgroup. Mutat. Res. Genet. Toxicol. Environ. Mutagen. 783, 23-35.
    • (2015) Mutat. Res. Genet. Toxicol. Environ. Mutagen. , vol.783 , pp. 23-35
    • Gollapudi, B.B.1    Lynch, A.M.2    Hefich, R.H.3
  • 38
    • 84869753046 scopus 로고    scopus 로고
    • Eff-cient monitoring of in vivo pig - A gene mutation and chromosomal damage: Summary of 7 published studies and results from 11 new reference compounds
    • Dertinger, S. D., Phonethepswath, S., Avlasevich, S. L., et al. (2012) Eff-cient monitoring of in vivo pig - A gene mutation and chromosomal damage: summary of 7 published studies and results from 11 new reference compounds. Toxicol. Sci., 130, 328-348.
    • (2012) Toxicol. Sci. , vol.130 , pp. 328-348
    • Dertinger, S.D.1    Phonethepswath, S.2    Avlasevich, S.L.3
  • 39
    • 84863778329 scopus 로고    scopus 로고
    • In vivo fow cytometric Pig - A and micronucleus assays: Highly sensitive discrimination of the carcinogen/noncarcinogen pair benzo(a)pyrene and pyrene using acute and repeated-dose designs
    • Torous, D. K., Phonethepswath, S., Avlasevich, S. L., et al. (2012) In vivo fow cytometric Pig - A and micronucleus assays: highly sensitive discrimination of the carcinogen/noncarcinogen pair benzo(a)pyrene and pyrene using acute and repeated-dose designs. Environ. Mol. Mutagen., 53, 420- 428.
    • (2012) Environ. Mol. Mutagen. , vol.53 , pp. 420-428
    • Torous, D.K.1    Phonethepswath, S.2    Avlasevich, S.L.3
  • 40
    • 54249128207 scopus 로고    scopus 로고
    • Development of an in vivo gene mutation assay using the endogenous Pig-A gene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat
    • Miura, D., Dobrovolsky, V. N., Kasahara, Y., Katsuura, Y. and Hefich, R. H. (2008) Development of an in vivo gene mutation assay using the endogenous Pig-A gene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat. Environ. Mol. Mutagen., 49, 614-621.
    • (2008) Environ. Mol. Mutagen. , vol.49 , pp. 614-621
    • Miura, D.1    Dobrovolsky, V.N.2    Kasahara, Y.3    Katsuura, Y.4    Hefich, R.H.5
  • 41
    • 54249134721 scopus 로고    scopus 로고
    • Development of an in vivo gene mutation assay using the endogenous Pig-A gene: II. Selection of Pig-A mutant rat spleen T-cells with proaerolysin and sequencing Pig-A cDNA from the mutants
    • Miura, D., Dobrovolsky, V. N., Mittelstaedt, R. A., Kasahara, Y., Katsuura, Y. and Hefich, R. H. (2008) Development of an in vivo gene mutation assay using the endogenous Pig-A gene: II. Selection of Pig-A mutant rat spleen T-cells with proaerolysin and sequencing Pig-A cDNA from the mutants. Environ. Mol. Mutagen., 49, 622-630.
    • (2008) Environ. Mol. Mutagen. , vol.49 , pp. 622-630
    • Miura, D.1    Dobrovolsky, V.N.2    Mittelstaedt, R.A.3    Kasahara, Y.4    Katsuura, Y.5    Hefich, R.H.6
  • 42
    • 4744353878 scopus 로고    scopus 로고
    • Subchronic acrylamide treatment induces a tissue-specific increase in DNA synthesis in the rat
    • Lafferty, J. S., Kamendulis, L. M., Kaster, J., Jiang, J. and Klaunig, J. E. (2004) Subchronic acrylamide treatment induces a tissue-specific increase in DNA synthesis in the rat. Toxicol. Lett., 154, 95-103.
    • (2004) Toxicol. Lett. , vol.154 , pp. 95-103
    • Lafferty, J.S.1    Kamendulis, L.M.2    Kaster, J.3    Jiang, J.4    Klaunig, J.E.5
  • 45
    • 0031802905 scopus 로고    scopus 로고
    • An automated method for discriminating aneugen- vs. Clastogen-induced micronuclei
    • Torous, D. K., Dertinger, S. D., Hall, N. E. and Tometsko, C. R. (1998) An automated method for discriminating aneugen- vs. clastogen-induced micronuclei. Environ. Mol. Mutagen., 31, 340-344.
    • (1998) Environ. Mol. Mutagen. , vol.31 , pp. 340-344
    • Torous, D.K.1    Dertinger, S.D.2    Hall, N.E.3    Tometsko, C.R.4
  • 46
    • 78650658372 scopus 로고    scopus 로고
    • Miniaturized fow cytometry-based CHO-K1 micronucleus assay discriminates aneugenic and clastogenic modes of action
    • Bryce, S. M., Avlasevich, S. L., Bemis, J. C. and Dertinger, S. D. (2011) Miniaturized fow cytometry-based CHO-K1 micronucleus assay discriminates aneugenic and clastogenic modes of action. Environ. Mol. Muta-gen., 52, 280-286.
    • (2011) Environ. Mol. Muta-gen. , vol.52 , pp. 280-286
    • Bryce, S.M.1    Avlasevich, S.L.2    Bemis, J.C.3    Dertinger, S.D.4
  • 47
    • 84921486205 scopus 로고    scopus 로고
    • Integrating toxi-cogenomics into human health risk assessment: Lessons learned from the benzo[a]pyrene case study
    • Chepelev, N. L., Moffat, I. D., Labib, S., et al. (2015) Integrating toxi-cogenomics into human health risk assessment: lessons learned from the benzo[a]pyrene case study. Crit. Rev. Toxicol. 45, 44-52.
    • (2015) Crit. Rev. Toxicol. , vol.45 , pp. 44-52
    • Chepelev, N.L.1    Moffat, I.D.2    Labib, S.3
  • 48
    • 42949122947 scopus 로고    scopus 로고
    • In vivo mutation assay based on the endogenous Pig - A locus
    • Bryce, S. M., Bemis, J. C. and Dertinger, S. D. (2008) In vivo mutation assay based on the endogenous Pig - A locus. Environ. Mol. Mutagen., 49, 256-264.
    • (2008) Environ. Mol. Mutagen. , vol.49 , pp. 256-264
    • Bryce, S.M.1    Bemis, J.C.2    Dertinger, S.D.3
  • 50
    • 84928005033 scopus 로고    scopus 로고
    • Human erythrocyte PIG-A assay: An easily monitored index of gene mutation requiring low volume blood samples
    • Dertinger, S. D., Avlasevich, S. L., Bemis, J. C., Chen, Y. and MacGregor, J. T. (2015) Human erythrocyte PIG-A assay: an easily monitored index of gene mutation requiring low volume blood samples. Environ. Mol. Muta-gen., 56, 366-377.
    • (2015) Environ. Mol. Muta-gen. , vol.56 , pp. 366-377
    • Dertinger, S.D.1    Avlasevich, S.L.2    Bemis, J.C.3    Chen, Y.4    MacGregor, J.T.5
  • 51
    • 0028046590 scopus 로고
    • Molecular cloning of murine pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function, and genetic locus
    • Kawagoe, K., Takeda, J., Endo, Y. and Kinoshita, T. (1994) Molecular cloning of murine pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function, and genetic locus. Genomics, 23, 566-574.
    • (1994) Genomics , vol.23 , pp. 566-574
    • Kawagoe, K.1    Takeda, J.2    Endo, Y.3    Kinoshita, T.4
  • 53
    • 0028181694 scopus 로고
    • Molecular analysis of lacI mutants from bone marrow of B6C3F1 transgenic mice following inhalation exposure to 1,3-butadiene
    • Sisk, S. C., Pluta, L. J., Bond, J. A. and Recio, L. (1994) Molecular analysis of lacI mutants from bone marrow of B6C3F1 transgenic mice following inhalation exposure to 1,3-butadiene. Carcinogenesis, 15, 471-477.
    • (1994) Carcinogenesis , vol.15 , pp. 471-477
    • Sisk, S.C.1    Pluta, L.J.2    Bond, J.A.3    Recio, L.4
  • 54
    • 0032937876 scopus 로고    scopus 로고
    • Spontaneous mutation spectrum at the lambda cII locus in liver, lung, and spleen tissue of Big Blue transgenic mice
    • Harbach, P. R., Zimmer, D. M., Filipunas, A. L., Mattes, W. B. and Aaron, C. S. (1999) Spontaneous mutation spectrum at the lambda cII locus in liver, lung, and spleen tissue of Big Blue transgenic mice. Environ. Mol. Mutagen., 33, 132-143.
    • (1999) Environ. Mol. Mutagen. , vol.33 , pp. 132-143
    • Harbach, P.R.1    Zimmer, D.M.2    Filipunas, A.L.3    Mattes, W.B.4    Aaron, C.S.5
  • 58
    • 33750304696 scopus 로고    scopus 로고
    • Relationships between biomarkers of exposure and toxicokinetics in Fischer 344 rats and B6C3F1 mice administered single doses of acrylamide and glycidamide and multiple doses of acrylamide
    • Tareke, E., Twaddle, N. C., McDaniel, L. P., Churchwell, M. I., Young, J. F. and Doerge, D. R. (2006) Relationships between biomarkers of exposure and toxicokinetics in Fischer 344 rats and B6C3F1 mice administered single doses of acrylamide and glycidamide and multiple doses of acrylamide. Toxicol. Appl. Pharmacol., 217, 63-75.
    • (2006) Toxicol. Appl. Pharmacol. , vol.217 , pp. 63-75
    • Tareke, E.1    Twaddle, N.C.2    McDaniel, L.P.3    Churchwell, M.I.4    Young, J.F.5    Doerge, D.R.6
  • 60
  • 61
    • 84899639346 scopus 로고    scopus 로고
    • Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence
    • Meek, M. E., Palermo, C. M., Bachman, A. N., North, C. M. and Jeffrey Lewis, R. (2014) Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence. J. Appl. Toxicol., 34, 595-606.
    • (2014) J. Appl. Toxicol. , vol.34 , pp. 595-606
    • Meek, M.E.1    Palermo, C.M.2    Bachman, A.N.3    North, C.M.4    Jeffrey Lewis, R.5
  • 62
    • 0029028549 scopus 로고
    • Formation of N-7-(2-carbamoyl-2-hydroxyethyl)guanine in DNA of the mouse and the rat following intraperitoneal administration of [14C]acrylamide
    • Segerbäck, D., Calleman, C. J., Schroeder, J. L., Costa, L. G. and Faustman, E. M. (1995) Formation of N-7-(2-carbamoyl-2-hydroxyethyl)guanine in DNA of the mouse and the rat following intraperitoneal administration of [14C]acrylamide. Carcinogenesis, 16, 1161-1165.
    • (1995) Carcinogenesis , vol.16 , pp. 1161-1165
    • Segerbäck, D.1    Calleman, C.J.2    Schroeder, J.L.3    Costa, L.G.4    Faustman, E.M.5
  • 63
    • 33644868336 scopus 로고    scopus 로고
    • Mechanisms of acrylamide induced rodent carcinogenesis
    • Klaunig, J. E. and Kamendulis, L. M. (2005) Mechanisms of acrylamide induced rodent carcinogenesis. Adv. Exp. Med. Biol., 561, 49-62.
    • (2005) Adv. Exp. Med. Biol. , vol.561 , pp. 49-62
    • Klaunig, J.E.1    Kamendulis, L.M.2
  • 65
    • 34250744083 scopus 로고    scopus 로고
    • Acryla-mide effects on kinesin-related proteins of the mitotic/meiotic spindle
    • Sickles, D. W., Sperry, A. O., Testino, A. and Friedman, M. (2007) Acryla-mide effects on kinesin-related proteins of the mitotic/meiotic spindle. Toxicol. Appl. Pharmacol., 222, 111-121.
    • (2007) Toxicol. Appl. Pharmacol. , vol.222 , pp. 111-121
    • Sickles, D.W.1    Sperry, A.O.2    Testino, A.3    Friedman, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.