Evaluation of the mutagenicity of alkylating agents, methylnitrosourea and temozolomide, using the rat Pig-a assay with total red blood cells or reticulocytes

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 811, Issue , 2016, Pages 117-122

  Muto, Shigeharu ^a   Yamada, Katsuya ^a   Kato, Tatsuya ^a   Ando, Masamitsu ^a   Inoue, Yoshimi ^a   Iwase, Yumiko ^a   Uno, Yoshifumi ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Flow cytometry; Methylnitrosourea; Phosphatidylinositol glycan complementation class A gene; Pig a assay; Temozolomide

Indexed keywords

METHYLNITROSOUREA; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL GLYCAN CLASS A; TEMOZOLOMIDE; UNCLASSIFIED DRUG; ALKYLATING AGENT; DACARBAZINE; MEMBRANE PROTEIN; MUTAGENIC AGENT; PHOSPHATIDYLINOSITOL GLYCAN-CLASS A PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; BONE MARROW; CHROMOSOME ABERRATION; CLINICAL EVALUATION; CONTROLLED STUDY; ERYTHROCYTE; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MICRONUCLEUS TEST; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RETICULOCYTE; ANALOGS AND DERIVATIVES; ANIMAL; BODY WEIGHT; DRUG EFFECTS; EVALUATION STUDY; GENETICS; MUTAGEN TESTING; PROCEDURES; SPRAGUE DAWLEY RAT;

ALKYLATING AGENTS; ANIMALS; BODY WEIGHT; DACARBAZINE; ERYTHROCYTES; MALE; MEMBRANE PROTEINS; METHYLNITROSOUREA; MUTAGENICITY TESTS; MUTAGENS; RATS; RATS, SPRAGUE-DAWLEY; RETICULOCYTES;

EID: 84960155827     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2016.01.010     Document Type: Article

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