Detection of Pig-a gene mutants in rat peripheral blood following a single urethane treatment: A comparison of the RBC Pig-a and PIGRET assays

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 811, Issue , 2016, Pages 129-134

  Narumi, Kazunori ^a   Fujiishi, Yohei ^a   Okada, Emiko ^a   Ohyama, Wakako ^a  

^a YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

Author keywords

In vivo mutation assay; Peripheral blood; Pig a gene; Reticulocyte; Urethane

Indexed keywords

CARCINOGEN; URETHAN; MEMBRANE PROTEIN; MUTAGENIC AGENT; PHOSPHATIDYLINOSITOL GLYCAN-CLASS A PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD; BLOOD SAMPLING; CELL ASSAY; CONTROLLED STUDY; ERYTHROCYTE; FREQUENCY; GENE MUTATION; GENETIC SCREENING; GENOTOXICITY; IN VIVO STUDY; INTERMETHOD COMPARISON; JAPAN; MALE; MUTAGENICITY; MUTANT; NONHUMAN; PRIORITY JOURNAL; RAT; RED BLOOD CELL PIG A ASSAY; RETICULOCYTE COUNT; RISK ASSESSMENT; SCREENING TEST; WEIGHT CHANGE; ANIMAL; BODY WEIGHT; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; MUTAGEN TESTING; MUTATION; PROCEDURES; RETICULOCYTE; SPRAGUE DAWLEY RAT;

ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; MALE; MEMBRANE PROTEINS; MUTAGENICITY TESTS; MUTAGENS; MUTATION; RATS; RATS, SPRAGUE-DAWLEY; RETICULOCYTES; URETHANE;

EID: 84961223546     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2016.02.004     Document Type: Article

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