Measuring reproducibility of dose response data for the Pig-a assay using covariate benchmark dose analysis

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 811, Issue , 2016, Pages 135-139

  Johnson, George E ^a   Yamamoto, Mika ^b   Suzuki, Yuta ^c   Adachi, Hideki ^d   Kyoya, Takahiro ^e   Takasawa, Hironao ^f   Horibata, Katsuyoshi ^g   Tsutsumi, Eri ^h   Wada, Kunio ⁱ   Kikuzuki, Ryuta ^j   Yoshida, Ikuma ^k   Kimoto, Takafumi ^l   Maeda, Akihisa ^m   Narumi, Kazunori ⁿ  

^a SWANSEA UNIVERSITY   (United Kingdom)

^b ASTELLAS PHARMA INC   (Japan)

^c Research Center Inc   (Japan)

^d DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^e KUMIAI CHEMICAL INDUSTRY CO LTD   (Japan)

^f LSI MEDIENCE CORPORATION   (Japan)

^g NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^h SUNTORY LTD   (Japan)

ⁱ INSTITUTE OF ENVIRONMENTAL TOXICOLOGY   (Japan)

^j TAISHO PHARMACEUTICAL CO LTD   (Japan)

^k TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^l TEIJIN PHARMA LIMITED   (Japan)

^m TORAY INDUSTRIES INC   (Japan)

ⁿ YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

more..

Author keywords

Benchmark dose; Dose response; In vivo; OECD; Pig a; Potency; Ring trial

Indexed keywords

BROXURIDINE; ETHYLNITROSOUREA; MEMBRANE PROTEIN; MUTAGENIC AGENT; PHOSPHATIDYLINOSITOL GLYCAN-CLASS A PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BENCHMARKING; CONFIDENCE INTERVAL; DOSE RESPONSE; ERYTHROCYTE; FLOW CYTOMETRY; GENE; GENE DOSAGE; GENE MUTATION; NONHUMAN; PIG-A GENE; PRIORITY JOURNAL; RAT; REPRODUCIBILITY; RETICULOCYTE; ANIMAL; DRUG EFFECTS; GENETICS; MUTAGEN TESTING; MUTATION; PROCEDURES;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; MEMBRANE PROTEINS; MUTAGENICITY TESTS; MUTAGENS; MUTATION; RATS; REPRODUCIBILITY OF RESULTS; RETICULOCYTES;

EID: 84964652597     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2016.04.004     Document Type: Article

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