Development of an in vivo gene mutation assay using the endogenous Pig-A gene: II. Selection of Pig-A mutant rat spleen T-cells with proaerolysin and sequencing Pig-A cDNA from the mutants

Environmental and Molecular Mutagenesis

Volumn 49, Issue 8, 2008, Pages 622-630

  Miura, Daishiro ^a,b   Dobrovolsky, Vasily N ^a   Mittelstaedt, Roberta A ^a   Kasahara, Yoshinori ^b   Katsuura, Yasuhiro ^b   Heflich, Robert H ^a,c  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b TEIJIN PHARMA LIMITED   (Japan)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Aerolysin; CD48; F344 rats; Flow cytometry; Glycosylphosphatidylinositol; N ethyl N nitrosourea

Indexed keywords

AEROLYSIN; CD48 ANTIGEN; COMPLEMENTARY DNA; ETHYLNITROSOUREA; GLYCOSYLPHOSPHATIDYLINOSITOL; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE;

ANIMAL CELL; ARTICLE; BASE PAIRING; CELL ISOLATION; CONTROLLED STUDY; DILUTION; DNA SEQUENCE; EXON; FLOW CYTOMETRY; GENE; GENE DELETION; GENE MUTATION; GENE SEQUENCE; LYMPHOCYTE CULTURE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PIG A GENE; RAT; SPLEEN CELL; T LYMPHOCYTE;

ANIMALS; BACTERIAL TOXINS; BASE SEQUENCE; CELLS, CULTURED; DNA PRIMERS; DNA, COMPLEMENTARY; FLOW CYTOMETRY; MEMBRANE PROTEINS; MUTATION; PORE FORMING CYTOTOXIC PROTEINS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN; T-LYMPHOCYTES;

RATTUS; SUIDAE;

EID: 54249134721     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20413     Document Type: Article

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