-
1
-
-
0022541957
-
‘Acute’ autoimmune hepatitis
-
COI: 1:STN:280:DyaL2s%2FgsFKltA%3D%3D, PID: 3758517
-
Crapper RM, Bhathal PS, Mackay IR, Frazer IH. ‘Acute’ autoimmune hepatitis. Digestion. 1986;34:216–225.
-
(1986)
Digestion
, vol.34
, pp. 216-225
-
-
Crapper, R.M.1
Bhathal, P.S.2
Mackay, I.R.3
Frazer, I.H.4
-
2
-
-
0028027857
-
The nature and prognostic implications of autoimmune hepatitis with an acute presentation
-
COI: 1:STN:280:DyaK2M7pslyiug%3D%3D, PID: 7890904
-
Nikias GA, Batts KP, Czaja AJ. The nature and prognostic implications of autoimmune hepatitis with an acute presentation. J Hepatol. 1994;21:866–871.
-
(1994)
J Hepatol
, vol.21
, pp. 866-871
-
-
Nikias, G.A.1
Batts, K.P.2
Czaja, A.J.3
-
3
-
-
0029057518
-
Recent-onset autoimmune hepatitis. Biopsy findings and clinical correlations
-
COI: 1:STN:280:DyaK2M3nsVOqsQ%3D%3D, PID: 7755156
-
Burgart LJ, Batts KP, Ludwig J, Nikias GA, Czaja AJ. Recent-onset autoimmune hepatitis. Biopsy findings and clinical correlations. Am J Surg Pathol. 1995;19:699–708.
-
(1995)
Am J Surg Pathol
, vol.19
, pp. 699-708
-
-
Burgart, L.J.1
Batts, K.P.2
Ludwig, J.3
Nikias, G.A.4
Czaja, A.J.5
-
4
-
-
73149085031
-
Autoimmune hepatitis with acute presentation in Japan
-
COI: 1:CAS:528:DC%2BC3cXnsF2jurY%3D, PID: 19473895
-
Miyake Y, Iwasaki Y, Kobashi H, et al. Autoimmune hepatitis with acute presentation in Japan. Dig Liver Dis. 2010;42:51–54.
-
(2010)
Dig Liver Dis
, vol.42
, pp. 51-54
-
-
Miyake, Y.1
Iwasaki, Y.2
Kobashi, H.3
-
5
-
-
84876691081
-
Acute and acute severe (fulminant) autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BC3sXlslShtbw%3D, PID: 23090425
-
Czaja AJ. Acute and acute severe (fulminant) autoimmune hepatitis. Dig Dis Sci. 2013;58:897–914.
-
(2013)
Dig Dis Sci
, vol.58
, pp. 897-914
-
-
Czaja, A.J.1
-
6
-
-
3042535422
-
Fulminant hepatic failure as the initial presentation of acute autoimmune hepatitis
-
PID: 15224287
-
Kessler WR, Cummings OW, Eckert G, et al. Fulminant hepatic failure as the initial presentation of acute autoimmune hepatitis. Clin Gastroenterol Hepatol. 2004;2:625–631.
-
(2004)
Clin Gastroenterol Hepatol
, vol.2
, pp. 625-631
-
-
Kessler, W.R.1
Cummings, O.W.2
Eckert, G.3
-
7
-
-
79954414704
-
Clinicopathological features of severe and fulminant forms of autoimmune hepatitis
-
PID: 20821236
-
Yasui S, Fujiwara K, Yonemitsu Y, et al. Clinicopathological features of severe and fulminant forms of autoimmune hepatitis. J Gastroenterol. 2011;46:378–390.
-
(2011)
J Gastroenterol
, vol.46
, pp. 378-390
-
-
Yasui, S.1
Fujiwara, K.2
Yonemitsu, Y.3
-
8
-
-
79251531139
-
Autoimmune fulminant liver failure in adults: experience in a Japanese center
-
PID: 21269383
-
Fujiwara K, Yasui S, Tawada A, et al. Autoimmune fulminant liver failure in adults: experience in a Japanese center. Hepatol Res. 2011;41:133–141.
-
(2011)
Hepatol Res
, vol.41
, pp. 133-141
-
-
Fujiwara, K.1
Yasui, S.2
Tawada, A.3
-
9
-
-
0025183812
-
Auto-immune (lupoid) hepatitis: an entity in the spectrum of chronic active liver disease
-
COI: 1:STN:280:DyaK3MzlsFyjsg%3D%3D, PID: 2103416
-
Mackay IR. Auto-immune (lupoid) hepatitis: an entity in the spectrum of chronic active liver disease. J Gastroenterol Hepatol. 1990;5:352–359.
-
(1990)
J Gastroenterol Hepatol
, vol.5
, pp. 352-359
-
-
Mackay, I.R.1
-
10
-
-
2542572604
-
Progressive fibrosis during corticosteroid therapy of autoimmune hepatitis
-
PID: 15185304
-
Czaja AJ, Carpenter HA. Progressive fibrosis during corticosteroid therapy of autoimmune hepatitis. Hepatology. 2004;39:1631–1638.
-
(2004)
Hepatology
, vol.39
, pp. 1631-1638
-
-
Czaja, A.J.1
Carpenter, H.A.2
-
11
-
-
67349145925
-
Rapidity of treatment response and outcome in type 1 autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BD1MXntVKgurs%3D, PID: 19446908
-
Czaja AJ. Rapidity of treatment response and outcome in type 1 autoimmune hepatitis. J Hepatol. 2009;51:161–167.
-
(2009)
J Hepatol
, vol.51
, pp. 161-167
-
-
Czaja, A.J.1
-
12
-
-
84896826716
-
Hepatic inflammation and progressive liver fibrosis in chronic liver disease
-
COI: 1:CAS:528:DC%2BC2cXhtlOnsLvK, PID: 24627588
-
Czaja AJ. Hepatic inflammation and progressive liver fibrosis in chronic liver disease. World J Gastroenterol. 2014;20:2515–2532.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 2515-2532
-
-
Czaja, A.J.1
-
13
-
-
0029039362
-
Histological grading and staging of chronic hepatitis
-
COI: 1:STN:280:DyaK28%2FjsFWntw%3D%3D, PID: 7560864
-
Ishak K, Baptista A, Bianchi L, et al. Histological grading and staging of chronic hepatitis. J Hepatol. 1995;22:696–699.
-
(1995)
J Hepatol
, vol.22
, pp. 696-699
-
-
Ishak, K.1
Baptista, A.2
Bianchi, L.3
-
14
-
-
0021749087
-
Development and prognosis of histologic cirrhosis in corticosteroid-treated hepatitis B surface antigen-negative chronic active hepatitis
-
COI: 1:STN:280:DyaL2M%2FivVamuw%3D%3D, PID: 6489694
-
Davis GL, Czaja AJ, Ludwig J. Development and prognosis of histologic cirrhosis in corticosteroid-treated hepatitis B surface antigen-negative chronic active hepatitis. Gastroenterology. 1984;87:1222–1227.
-
(1984)
Gastroenterology
, vol.87
, pp. 1222-1227
-
-
Davis, G.L.1
Czaja, A.J.2
Ludwig, J.3
-
15
-
-
0030065386
-
Prognosis of histological cirrhosis in type 1 autoimmune hepatitis
-
COI: 1:STN:280:DyaK287nslOguw%3D%3D, PID: 8608895
-
Roberts SK, Therneau TM, Czaja AJ. Prognosis of histological cirrhosis in type 1 autoimmune hepatitis. Gastroenterology. 1996;110:848–857.
-
(1996)
Gastroenterology
, vol.110
, pp. 848-857
-
-
Roberts, S.K.1
Therneau, T.M.2
Czaja, A.J.3
-
16
-
-
0026571063
-
Prognostic features and role of liver transplantation in severe corticosteroid-treated autoimmune chronic active hepatitis
-
COI: 1:STN:280:DyaK387jslyqtA%3D%3D, PID: 1735524
-
Sanchez-Urdazpal L, Czaja AJ, van Hoek B, Krom RA, Wiesner RH. Prognostic features and role of liver transplantation in severe corticosteroid-treated autoimmune chronic active hepatitis. Hepatology. 1992;15:215–221.
-
(1992)
Hepatology
, vol.15
, pp. 215-221
-
-
Sanchez-Urdazpal, L.1
Czaja, A.J.2
van Hoek, B.3
Krom, R.A.4
Wiesner, R.H.5
-
17
-
-
0031049137
-
Autoimmune hepatitis in childhood: a 20-year experience
-
COI: 1:STN:280:DyaK2s3gtFCjuw%3D%3D, PID: 9049195
-
Gregorio GV, Portmann B, Reid F, et al. Autoimmune hepatitis in childhood: a 20-year experience. Hepatology. 1997;25:541–547.
-
(1997)
Hepatology
, vol.25
, pp. 541-547
-
-
Gregorio, G.V.1
Portmann, B.2
Reid, F.3
-
18
-
-
36349017310
-
Features associated with treatment failure in type 1 autoimmune hepatitis and predictive value of the model of end-stage liver disease
-
COI: 1:CAS:528:DC%2BD2sXht1aksrrI, PID: 17668882
-
Montano-Loza AJ, Carpenter HA, Czaja AJ. Features associated with treatment failure in type 1 autoimmune hepatitis and predictive value of the model of end-stage liver disease. Hepatology. 2007;46:1138–1145.
-
(2007)
Hepatology
, vol.46
, pp. 1138-1145
-
-
Montano-Loza, A.J.1
Carpenter, H.A.2
Czaja, A.J.3
-
19
-
-
70350523350
-
Risk factors for recurrence of autoimmune hepatitis after liver transplantation
-
PID: 19790153
-
Montano-Loza AJ, Mason AL, Ma M, et al. Risk factors for recurrence of autoimmune hepatitis after liver transplantation. Liver Transpl. 2009;15:1254–1261.
-
(2009)
Liver Transpl
, vol.15
, pp. 1254-1261
-
-
Montano-Loza, A.J.1
Mason, A.L.2
Ma, M.3
-
20
-
-
77952711598
-
Diagnosis and management of autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BC3cXnslyqtbc%3D, PID: 20513004
-
Manns MP, Czaja AJ, Gorham JD, et al. Diagnosis and management of autoimmune hepatitis. Hepatology. 2010;51:2193–2213.
-
(2010)
Hepatology
, vol.51
, pp. 2193-2213
-
-
Manns, M.P.1
Czaja, A.J.2
Gorham, J.D.3
-
21
-
-
49349095701
-
Predictive factors for hepatocellular carcinoma in type 1 autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BD1cXhtFGhur3E, PID: 18564111
-
Montano-Loza AJ, Carpenter HA, Czaja AJ. Predictive factors for hepatocellular carcinoma in type 1 autoimmune hepatitis. Am J Gastroenterol. 2008;103:1944–1951.
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 1944-1951
-
-
Montano-Loza, A.J.1
Carpenter, H.A.2
Czaja, A.J.3
-
22
-
-
51349099034
-
Evaluation of risk factors in the development of hepatocellular carcinoma in autoimmune hepatitis: implications for follow-up and screening
-
PID: 18752332
-
Yeoman AD, Al-Chalabi T, Karani JB, et al. Evaluation of risk factors in the development of hepatocellular carcinoma in autoimmune hepatitis: implications for follow-up and screening. Hepatology. 2008;48:863–870.
-
(2008)
Hepatology
, vol.48
, pp. 863-870
-
-
Yeoman, A.D.1
Al-Chalabi, T.2
Karani, J.B.3
-
23
-
-
1642285767
-
Decreased fibrosis during corticosteroid therapy of autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BD2cXitFKhsLg%3D, PID: 15030981
-
Czaja AJ, Carpenter HA. Decreased fibrosis during corticosteroid therapy of autoimmune hepatitis. J Hepatol. 2004;40:646–652.
-
(2004)
J Hepatol
, vol.40
, pp. 646-652
-
-
Czaja, A.J.1
Carpenter, H.A.2
-
24
-
-
0027269438
-
Survival and histological resolution of fibrosis in patients with autoimmune chronic active hepatitis
-
COI: 1:STN:280:DyaK3szktVCgsQ%3D%3D, PID: 7688011
-
Schvarcz R, Glaumann H, Weiland O. Survival and histological resolution of fibrosis in patients with autoimmune chronic active hepatitis. J Hepatol. 1993;18:15–23.
-
(1993)
J Hepatol
, vol.18
, pp. 15-23
-
-
Schvarcz, R.1
Glaumann, H.2
Weiland, O.3
-
25
-
-
0030692704
-
Reversibility of hepatic fibrosis in autoimmune hepatitis
-
COI: 1:STN:280:DyaK1c%2FjtF2ltQ%3D%3D, PID: 9412303
-
Dufour JF, DeLellis R, Kaplan MM. Reversibility of hepatic fibrosis in autoimmune hepatitis. Ann Intern Med. 1997;127:981–985.
-
(1997)
Ann Intern Med
, vol.127
, pp. 981-985
-
-
Dufour, J.F.1
DeLellis, R.2
Kaplan, M.M.3
-
26
-
-
0035040359
-
Resolution of cirrhosis in autoimmune hepatitis with corticosteroid therapy
-
COI: 1:STN:280:DC%2BD3M3jtFSksw%3D%3D, PID: 11319316
-
Cotler SJ, Jakate S, Jensen DM. Resolution of cirrhosis in autoimmune hepatitis with corticosteroid therapy. J Clin Gastroenterol. 2001;32:428–430.
-
(2001)
J Clin Gastroenterol
, vol.32
, pp. 428-430
-
-
Cotler, S.J.1
Jakate, S.2
Jensen, D.M.3
-
27
-
-
17444393210
-
Impact of immunosuppressive treatment on liver fibrosis in autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BD2MXisFKhtro%3D, PID: 15810640
-
Mohamadnejad M, Malekzadeh R, Nasseri-Moghaddam S, et al. Impact of immunosuppressive treatment on liver fibrosis in autoimmune hepatitis. Dig Dis Sci. 2005;50:547–551.
-
(2005)
Dig Dis Sci
, vol.50
, pp. 547-551
-
-
Mohamadnejad, M.1
Malekzadeh, R.2
Nasseri-Moghaddam, S.3
-
28
-
-
0026631757
-
Reversibility of secondary biliary fibrosis by biliodigestive anastomosis in the rat
-
COI: 1:STN:280:DyaK38zjvFygtA%3D%3D, PID: 1634077
-
Zimmermann H, Reichen J, Zimmermann A, et al. Reversibility of secondary biliary fibrosis by biliodigestive anastomosis in the rat. Gastroenterology. 1992;103:579–589.
-
(1992)
Gastroenterology
, vol.103
, pp. 579-589
-
-
Zimmermann, H.1
Reichen, J.2
Zimmermann, A.3
-
29
-
-
0028349842
-
Reversal of advanced liver fibrosis in rabbits with Schistosomiasis japonica
-
COI: 1:STN:280:DyaK2c3hvFOjuw%3D%3D, PID: 8166357
-
Dunn MA, Cheever AW, Paglia LM, et al. Reversal of advanced liver fibrosis in rabbits with Schistosomiasis japonica. Am J Trop Med Hyg. 1994;50:499–505.
-
(1994)
Am J Trop Med Hyg
, vol.50
, pp. 499-505
-
-
Dunn, M.A.1
Cheever, A.W.2
Paglia, L.M.3
-
30
-
-
0015185248
-
Observer error and sampling variability tested in evaluation of hepatitis and cirrhosis by liver biopsy
-
COI: 1:STN:280:DyaE38%2FoslCksg%3D%3D, PID: 5135770
-
Soloway RD, Baggenstoss AH, Schoenfield LJ, Summerskill WH. Observer error and sampling variability tested in evaluation of hepatitis and cirrhosis by liver biopsy. Am J Dig Dis. 1971;16:1082–1086.
-
(1971)
Am J Dig Dis
, vol.16
, pp. 1082-1086
-
-
Soloway, R.D.1
Baggenstoss, A.H.2
Schoenfield, L.J.3
Summerskill, W.H.4
-
31
-
-
0018976635
-
Observer variation in assessment of liver biopsies including analysis by kappa statistics
-
COI: 1:STN:280:DyaL3c3kslentg%3D%3D, PID: 7399228
-
Theodossi A, Skene AM, Portmann B, et al. Observer variation in assessment of liver biopsies including analysis by kappa statistics. Gastroenterology. 1980;79:232–241.
-
(1980)
Gastroenterology
, vol.79
, pp. 232-241
-
-
Theodossi, A.1
Skene, A.M.2
Portmann, B.3
-
32
-
-
33644499498
-
Reversal of hepatic fibrosis—fact or fantasy?
-
COI: 1:CAS:528:DC%2BD28XhvVSktL8%3D, PID: 16447275
-
Friedman SL, Bansal MB. Reversal of hepatic fibrosis—fact or fantasy? Hepatology. 2006;43:S82–S88.
-
(2006)
Hepatology
, vol.43
, pp. S82-S88
-
-
Friedman, S.L.1
Bansal, M.B.2
-
33
-
-
42949163491
-
Mechanisms of hepatic fibrogenesis
-
COI: 1:CAS:528:DC%2BD1cXntF2gs7o%3D, PID: 18471545
-
Friedman SL. Mechanisms of hepatic fibrogenesis. Gastroenterology. 2008;134:1655–1669.
-
(2008)
Gastroenterology
, vol.134
, pp. 1655-1669
-
-
Friedman, S.L.1
-
35
-
-
80054758173
-
Current status of novel antifibrotic therapies in patients with chronic liver disease
-
COI: 1:CAS:528:DC%2BC3MXhsVGgtrzK, PID: 22043231
-
Cohen-Naftaly M, Friedman SL. Current status of novel antifibrotic therapies in patients with chronic liver disease. Therap Adv Gastroenterol. 2011;4:391–417.
-
(2011)
Therap Adv Gastroenterol
, vol.4
, pp. 391-417
-
-
Cohen-Naftaly, M.1
Friedman, S.L.2
-
36
-
-
84862162169
-
Fibrogenic cell reversion underlies fibrosis regression in liver
-
COI: 1:CAS:528:DC%2BC38Xptlait7k%3D, PID: 22645354
-
Friedman SL. Fibrogenic cell reversion underlies fibrosis regression in liver. Proc Natl Acad Sci USA. 2012;109:9230–9231.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 9230-9231
-
-
Friedman, S.L.1
-
37
-
-
84892883803
-
Review article: prevention and reversal of hepatic fibrosis in autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BC2cXhtlaks74%3D, PID: 24387318
-
Czaja AJ. Review article: prevention and reversal of hepatic fibrosis in autoimmune hepatitis. Aliment Pharmacol Ther. 2014;39:385–406.
-
(2014)
Aliment Pharmacol Ther
, vol.39
, pp. 385-406
-
-
Czaja, A.J.1
-
38
-
-
84901194707
-
Pathogenic role of oxidative and nitrosative stress in primary biliary cirrhosis
-
COI: 1:CAS:528:DC%2BC2cXhsVSgurvL, PID: 24914336
-
Grattagliano I, Calamita G, Cocco T, Wang DQ, Portincasa P. Pathogenic role of oxidative and nitrosative stress in primary biliary cirrhosis. World J Gastroenterol. 2014;20:5746–5759.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 5746-5759
-
-
Grattagliano, I.1
Calamita, G.2
Cocco, T.3
Wang, D.Q.4
Portincasa, P.5
-
39
-
-
84912528717
-
Targeting apoptosis in autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BC2cXht1Slt73K, PID: 25038736
-
Czaja AJ. Targeting apoptosis in autoimmune hepatitis. Dig Dis Sci. 2014;59:2890–2904.
-
(2014)
Dig Dis Sci
, vol.59
, pp. 2890-2904
-
-
Czaja, A.J.1
-
40
-
-
84904055092
-
Review article: chemokines as orchestrators of autoimmune hepatitis and potential therapeutic targets
-
COI: 1:CAS:528:DC%2BC2cXhtFCks7jI, PID: 24890045
-
Czaja AJ. Review article: chemokines as orchestrators of autoimmune hepatitis and potential therapeutic targets. Aliment Pharmacol Ther. 2014;40:261–279.
-
(2014)
Aliment Pharmacol Ther
, vol.40
, pp. 261-279
-
-
Czaja, A.J.1
-
42
-
-
84923482955
-
Hepatic inflammation and fibrosis: functional links and key pathways
-
PID: 25066777
-
Seki E, Schwabe RF. Hepatic inflammation and fibrosis: functional links and key pathways. Hepatology. 2015;61:1066–1079.
-
(2015)
Hepatology
, vol.61
, pp. 1066-1079
-
-
Seki, E.1
Schwabe, R.F.2
-
43
-
-
84940483315
-
Redox-fibrosis: impact of TGFbeta1 on ROS generators, mediators and functional consequences
-
COI: 1:CAS:528:DC%2BC2MXhsVajs77I, PID: 26335400
-
Richter K, Konzack A, Pihlajaniemi T, Heljasvaara R, Kietzmann T. Redox-fibrosis: impact of TGFbeta1 on ROS generators, mediators and functional consequences. Redox Biol. 2015;6:344–352.
-
(2015)
Redox Biol
, vol.6
, pp. 344-352
-
-
Richter, K.1
Konzack, A.2
Pihlajaniemi, T.3
Heljasvaara, R.4
Kietzmann, T.5
-
44
-
-
84921497292
-
Vitamin D inhibits development of liver fibrosis in an animal model but cannot ameliorate established cirrhosis
-
COI: 1:CAS:528:DC%2BC2MXis12ktbk%3D, PID: 25214398
-
Abramovitch S, Sharvit E, Weisman Y, et al. Vitamin D inhibits development of liver fibrosis in an animal model but cannot ameliorate established cirrhosis. Am J Physiol Gastrointest Liver Physiol. 2015;308:G112–G120.
-
(2015)
Am J Physiol Gastrointest Liver Physiol
, vol.308
, pp. G112-G120
-
-
Abramovitch, S.1
Sharvit, E.2
Weisman, Y.3
-
45
-
-
84925500322
-
1,25-(OH)(2)-vitamin D(3) prevents activation of hepatic stellate cells in vitro and ameliorates inflammatory liver damage but not fibrosis in the Abcb4(−/−) model
-
COI: 1:CAS:528:DC%2BC2MXjsleqt7g%3D, PID: 25712522
-
Reiter FP, Hohenester S, Nagel JM, et al. 1,25-(OH)(2)-vitamin D(3) prevents activation of hepatic stellate cells in vitro and ameliorates inflammatory liver damage but not fibrosis in the Abcb4(−/−) model. Biochem Biophys Res Commun. 2015;459:227–233.
-
(2015)
Biochem Biophys Res Commun
, vol.459
, pp. 227-233
-
-
Reiter, F.P.1
Hohenester, S.2
Nagel, J.M.3
-
46
-
-
84928883882
-
Vitamin D counteracts fibrogenic TGF-beta signalling in human hepatic stellate cells both receptor-dependently and independently
-
COI: 1:CAS:528:DC%2BC2MXotFKku78%3D, PID: 25134788
-
Beilfuss A, Sowa JP, Sydor S, et al. Vitamin D counteracts fibrogenic TGF-beta signalling in human hepatic stellate cells both receptor-dependently and independently. Gut. 2015;64:791–799.
-
(2015)
Gut
, vol.64
, pp. 791-799
-
-
Beilfuss, A.1
Sowa, J.P.2
Sydor, S.3
-
47
-
-
84942095322
-
1,25(OH)2D3 downregulates the Toll-like receptor 4-mediated inflammatory pathway and ameliorates liver injury in diabetic rats
-
COI: 1:CAS:528:DC%2BC28XhvFSju7k%3D, PID: 25906757
-
Wang H, Zhang Q, Chai Y, et al. 1,25(OH)2D3 downregulates the Toll-like receptor 4-mediated inflammatory pathway and ameliorates liver injury in diabetic rats. J Endocrinol Invest. 2015;38:1083–1091.
-
(2015)
J Endocrinol Invest
, vol.38
, pp. 1083-1091
-
-
Wang, H.1
Zhang, Q.2
Chai, Y.3
-
48
-
-
84930378011
-
Cell Mediators of autoimmune hepatitis and their therapeutic implications
-
PID: 25487192
-
Montano-Loza AJ, Czaja AJ. Cell Mediators of autoimmune hepatitis and their therapeutic implications. Dig Dis Sci. 2014;60:1528–1542.
-
(2014)
Dig Dis Sci
, vol.60
, pp. 1528-1542
-
-
Montano-Loza, A.J.1
Czaja, A.J.2
-
49
-
-
84942191608
-
Transitioning from idiopathic to explainable autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BC2MXovV2lsro%3D, PID: 25999246
-
Czaja AJ. Transitioning from idiopathic to explainable autoimmune hepatitis. Dig Dis Sci. 2015;60:2881–2900.
-
(2015)
Dig Dis Sci
, vol.60
, pp. 2881-2900
-
-
Czaja, A.J.1
-
50
-
-
38049120126
-
Apoptosis-associated antigens recognized by autoantibodies in patients with the autoimmune liver disease primary biliary cirrhosis
-
COI: 1:CAS:528:DC%2BD1cXjt12hu7o%3D, PID: 18060504
-
Berg CP, Stein GM, Keppeler H, et al. Apoptosis-associated antigens recognized by autoantibodies in patients with the autoimmune liver disease primary biliary cirrhosis. Apoptosis. 2008;13:63–75.
-
(2008)
Apoptosis
, vol.13
, pp. 63-75
-
-
Berg, C.P.1
Stein, G.M.2
Keppeler, H.3
-
51
-
-
35948958955
-
TLR4 enhances TGF-beta signaling and hepatic fibrosis
-
COI: 1:CAS:528:DC%2BD2sXht1Kmtr3O, PID: 17952090
-
Seki E, De Minicis S, Osterreicher CH, et al. TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nat Med. 2007;13:1324–1332.
-
(2007)
Nat Med
, vol.13
, pp. 1324-1332
-
-
Seki, E.1
De Minicis, S.2
Osterreicher, C.H.3
-
52
-
-
47149105036
-
Toll-like receptors and adaptor molecules in liver disease: update
-
COI: 1:CAS:528:DC%2BD1cXptFemu7o%3D, PID: 18506843
-
Seki E, Brenner DA. Toll-like receptors and adaptor molecules in liver disease: update. Hepatology. 2008;48:322–335.
-
(2008)
Hepatology
, vol.48
, pp. 322-335
-
-
Seki, E.1
Brenner, D.A.2
-
53
-
-
0038185316
-
Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
-
COI: 1:CAS:528:DC%2BD3sXktVWns7Y%3D, PID: 12717385
-
Paik YH, Schwabe RF, Bataller R, et al. Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology. 2003;37:1043–1055.
-
(2003)
Hepatology
, vol.37
, pp. 1043-1055
-
-
Paik, Y.H.1
Schwabe, R.F.2
Bataller, R.3
-
54
-
-
84896754721
-
Transcriptional repression of the transforming growth factor beta (TGF-beta) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor kappaB (NF-kappaB) p50 enhances TGF-beta signaling in hepatic stellate cells
-
COI: 1:CAS:528:DC%2BC2cXjvVyktrc%3D, PID: 24448807
-
Liu C, Chen X, Yang L, et al. Transcriptional repression of the transforming growth factor beta (TGF-beta) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor kappaB (NF-kappaB) p50 enhances TGF-beta signaling in hepatic stellate cells. J Biol Chem. 2014;289:7082–7091.
-
(2014)
J Biol Chem
, vol.289
, pp. 7082-7091
-
-
Liu, C.1
Chen, X.2
Yang, L.3
-
55
-
-
84856350648
-
Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut
-
COI: 1:CAS:528:DC%2BC38Xislemtb8%3D, PID: 22124143
-
Seki E, Schnabl B. Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut. J Physiol. 2012;590:447–458.
-
(2012)
J Physiol
, vol.590
, pp. 447-458
-
-
Seki, E.1
Schnabl, B.2
-
56
-
-
84858702708
-
Intestinal decontamination inhibits TLR4 dependent fibronectin-mediated cross-talk between stellate cells and endothelial cells in liver fibrosis in mice
-
COI: 1:CAS:528:DC%2BC38XktlaqtLw%3D, PID: 22173161
-
Zhu Q, Zou L, Jagavelu K, et al. Intestinal decontamination inhibits TLR4 dependent fibronectin-mediated cross-talk between stellate cells and endothelial cells in liver fibrosis in mice. J Hepatol. 2012;56:893–899.
-
(2012)
J Hepatol
, vol.56
, pp. 893-899
-
-
Zhu, Q.1
Zou, L.2
Jagavelu, K.3
-
57
-
-
84873966954
-
Role of gut microbiota in liver diseases
-
COI: 1:CAS:528:DC%2BC3sXos1yqsbc%3D, PID: 22970713
-
Miyake Y, Yamamoto K. Role of gut microbiota in liver diseases. Hepatol Res. 2013;43:139–146.
-
(2013)
Hepatol Res
, vol.43
, pp. 139-146
-
-
Miyake, Y.1
Yamamoto, K.2
-
58
-
-
84949555568
-
Interaction of intestinal microorganisms with the human host in the framework of autoimmune diseases
-
PID: 26635808
-
Sanchez B, Hevia A, Gonzalez S, Margolles A. Interaction of intestinal microorganisms with the human host in the framework of autoimmune diseases. Front Immunol. 2015;6:594.
-
(2015)
Front Immunol
, vol.6
, pp. 594
-
-
Sanchez, B.1
Hevia, A.2
Gonzalez, S.3
Margolles, A.4
-
59
-
-
84886284340
-
Role of the intestinal microbiome in liver disease
-
COI: 1:CAS:528:DC%2BC3sXhsFeqt73M, PID: 24075647
-
Henao-Mejia J, Elinav E, Thaiss CA, Licona-Limon P, Flavell RA. Role of the intestinal microbiome in liver disease. J Autoimmun. 2013;46:66–73.
-
(2013)
J Autoimmun
, vol.46
, pp. 66-73
-
-
Henao-Mejia, J.1
Elinav, E.2
Thaiss, C.A.3
Licona-Limon, P.4
Flavell, R.A.5
-
60
-
-
84905166372
-
The interplay between the gut microbiota and the immune system
-
PID: 24922519
-
Geuking MB, Koller Y, Rupp S, McCoy KD. The interplay between the gut microbiota and the immune system. Gut Microbes. 2014;5:411–418.
-
(2014)
Gut Microbes
, vol.5
, pp. 411-418
-
-
Geuking, M.B.1
Koller, Y.2
Rupp, S.3
McCoy, K.D.4
-
61
-
-
84945466775
-
A novel “humanized mouse” model for autoimmune hepatitis and the association of gut microbiota with liver inflammation
-
COI: 1:CAS:528:DC%2BC2MXhslegt7nL, PID: 26185095
-
Yuksel M, Wang Y, Tai N, et al. A novel “humanized mouse” model for autoimmune hepatitis and the association of gut microbiota with liver inflammation. Hepatology. 2015;62:1536–1550.
-
(2015)
Hepatology
, vol.62
, pp. 1536-1550
-
-
Yuksel, M.1
Wang, Y.2
Tai, N.3
-
62
-
-
0018575527
-
The nature of piecemeal necrosis in chronic active hepatitis
-
COI: 1:STN:280:DyaL3c%2FjtFKmtg%3D%3D, PID: 90921
-
Kerr JF, Cooksley WG, Searle J, et al. The nature of piecemeal necrosis in chronic active hepatitis. Lancet. 1979;2:827–828.
-
(1979)
Lancet
, vol.2
, pp. 827-828
-
-
Kerr, J.F.1
Cooksley, W.G.2
Searle, J.3
-
63
-
-
0034919633
-
Apoptotic pathways in primary biliary cirrhosis and autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BD3MXmtVGnu7g%3D, PID: 11454191
-
Fox CK, Furtwaengler A, Nepomuceno RR, Martinez OM, Krams SM. Apoptotic pathways in primary biliary cirrhosis and autoimmune hepatitis. Liver. 2001;21:272–279.
-
(2001)
Liver
, vol.21
, pp. 272-279
-
-
Fox, C.K.1
Furtwaengler, A.2
Nepomuceno, R.R.3
Martinez, O.M.4
Krams, S.M.5
-
64
-
-
0041880709
-
Apoptosis and the liver: relation to autoimmunity and related conditions
-
PID: 12848974
-
Bai J, Odin JA. Apoptosis and the liver: relation to autoimmunity and related conditions. Autoimmun Rev. 2003;2:36–42.
-
(2003)
Autoimmun Rev
, vol.2
, pp. 36-42
-
-
Bai, J.1
Odin, J.A.2
-
65
-
-
0038476330
-
Apoptotic body engulfment by a human stellate cell line is profibrogenic
-
COI: 1:CAS:528:DC%2BD3sXjtlKjsL4%3D, PID: 12746475
-
Canbay A, Taimr P, Torok N, et al. Apoptotic body engulfment by a human stellate cell line is profibrogenic. Lab Invest. 2003;83:655–663.
-
(2003)
Lab Invest
, vol.83
, pp. 655-663
-
-
Canbay, A.1
Taimr, P.2
Torok, N.3
-
66
-
-
33645243410
-
Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo
-
COI: 1:CAS:528:DC%2BD28XjtVKqsLo%3D, PID: 16496318
-
Zhan SS, Jiang JX, Wu J, et al. Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo. Hepatology. 2006;43:435–443.
-
(2006)
Hepatology
, vol.43
, pp. 435-443
-
-
Zhan, S.S.1
Jiang, J.X.2
Wu, J.3
-
67
-
-
0024852111
-
Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors
-
COI: 1:CAS:528:DyaK3cXkvFCgsQ%3D%3D, PID: 2556445
-
Friedman SL, Arthur MJ. Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors. J Clin Invest. 1989;84:1780–1785.
-
(1989)
J Clin Invest
, vol.84
, pp. 1780-1785
-
-
Friedman, S.L.1
Arthur, M.J.2
-
68
-
-
84945733905
-
The role of thrombocytes in liver fibrogenesis: effects of platelet lysate and thrombocyte-derived growth factors on the mitogenic activity and glycosaminoglycan synthesis of cultured rat liver fat storing cells
-
COI: 1:CAS:528:DyaL1MXmtV2ksLg%3D, PID: 2607320
-
Bachem MG, Melchior R, Gressner AM. The role of thrombocytes in liver fibrogenesis: effects of platelet lysate and thrombocyte-derived growth factors on the mitogenic activity and glycosaminoglycan synthesis of cultured rat liver fat storing cells. J Clin Chem Clin Biochem. 1989;27:555–565.
-
(1989)
J Clin Chem Clin Biochem
, vol.27
, pp. 555-565
-
-
Bachem, M.G.1
Melchior, R.2
Gressner, A.M.3
-
69
-
-
0024314274
-
In vitro and in vivo association of transforming growth factor-beta 1 with hepatic fibrosis
-
COI: 1:CAS:528:DyaL1MXit12ntLg%3D, PID: 2500447
-
Czaja MJ, Weiner FR, Flanders KC, et al. In vitro and in vivo association of transforming growth factor-beta 1 with hepatic fibrosis. J Cell Biol. 1989;108:2477–2482.
-
(1989)
J Cell Biol
, vol.108
, pp. 2477-2482
-
-
Czaja, M.J.1
Weiner, F.R.2
Flanders, K.C.3
-
70
-
-
84864131030
-
Biological significance of local TGF-beta activation in liver diseases
-
COI: 1:CAS:528:DC%2BC38XjsVyhtbc%3D, PID: 22363291
-
Hayashi H, Sakai T. Biological significance of local TGF-beta activation in liver diseases. Front Physiol. 2012;3:12.
-
(2012)
Front Physiol
, vol.3
, pp. 12
-
-
Hayashi, H.1
Sakai, T.2
-
71
-
-
0034120267
-
Angiotensin II induces contraction and proliferation of human hepatic stellate cells
-
COI: 1:CAS:528:DC%2BD3cXktlaiu7w%3D, PID: 10833490
-
Bataller R, Gines P, Nicolas JM, et al. Angiotensin II induces contraction and proliferation of human hepatic stellate cells. Gastroenterology. 2000;118:1149–1156.
-
(2000)
Gastroenterology
, vol.118
, pp. 1149-1156
-
-
Bataller, R.1
Gines, P.2
Nicolas, J.M.3
-
72
-
-
0037772442
-
Activated human hepatic stellate cells express the renin–angiotensin system and synthesize angiotensin II
-
COI: 1:CAS:528:DC%2BD3sXmtVWqur4%3D, PID: 12851877
-
Bataller R, Sancho-Bru P, Gines P, et al. Activated human hepatic stellate cells express the renin–angiotensin system and synthesize angiotensin II. Gastroenterology. 2003;125:117–125.
-
(2003)
Gastroenterology
, vol.125
, pp. 117-125
-
-
Bataller, R.1
Sancho-Bru, P.2
Gines, P.3
-
73
-
-
36348997503
-
Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9
-
COI: 1:CAS:528:DC%2BD2sXhtlOiu7bL, PID: 17705260
-
Watanabe A, Hashmi A, Gomes DA, et al. Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology. 2007;46:1509–1518.
-
(2007)
Hepatology
, vol.46
, pp. 1509-1518
-
-
Watanabe, A.1
Hashmi, A.2
Gomes, D.A.3
-
74
-
-
84930625964
-
The dual role of Nrf2 in nonalcoholic fatty liver disease: regulation of antioxidant defenses and hepatic lipid metabolism
-
PID: 26120584
-
Chambel SS, Santos-Goncalves A, Duarte TL. The dual role of Nrf2 in nonalcoholic fatty liver disease: regulation of antioxidant defenses and hepatic lipid metabolism. Biomed Res Int. 2015;2015:597134.
-
(2015)
Biomed Res Int
, vol.2015
, pp. 597134
-
-
Chambel, S.S.1
Santos-Goncalves, A.2
Duarte, T.L.3
-
75
-
-
0035893937
-
The role of Kupffer cell oxidant production in early ethanol-induced liver disease
-
COI: 1:CAS:528:DC%2BD3MXptVahtLs%3D, PID: 11744328
-
Wheeler MD, Kono H, Yin M, et al. The role of Kupffer cell oxidant production in early ethanol-induced liver disease. Free Radic Biol Med. 2001;31:1544–1549.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 1544-1549
-
-
Wheeler, M.D.1
Kono, H.2
Yin, M.3
-
76
-
-
80052023895
-
NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation
-
COI: 1:CAS:528:DC%2BC3MXhtVOktrnO, PID: 21618578
-
Cui W, Matsuno K, Iwata K, et al. NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation. Hepatology. 2011;54:949–958.
-
(2011)
Hepatology
, vol.54
, pp. 949-958
-
-
Cui, W.1
Matsuno, K.2
Iwata, K.3
-
77
-
-
0033802236
-
NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease
-
COI: 1:CAS:528:DC%2BD3cXntVyiu7Y%3D, PID: 11018074
-
Kono H, Rusyn I, Yin M, et al. NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease. J Clin Invest. 2000;106:867–872.
-
(2000)
J Clin Invest
, vol.106
, pp. 867-872
-
-
Kono, H.1
Rusyn, I.2
Yin, M.3
-
79
-
-
79955091590
-
The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice
-
COI: 1:CAS:528:DC%2BC3MXltVygu7w%3D, PID: 21384410
-
Paik YH, Iwaisako K, Seki E, et al. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Hepatology. 2011;53:1730–1741.
-
(2011)
Hepatology
, vol.53
, pp. 1730-1741
-
-
Paik, Y.H.1
Iwaisako, K.2
Seki, E.3
-
80
-
-
84901056473
-
Role of NADPH oxidases in liver fibrosis
-
COI: 1:CAS:528:DC%2BC2cXotFGht70%3D, PID: 24040957
-
Paik YH, Kim J, Aoyama T, et al. Role of NADPH oxidases in liver fibrosis. Antioxid Redox Signal. 2014;20:2854–2872.
-
(2014)
Antioxid Redox Signal
, vol.20
, pp. 2854-2872
-
-
Paik, Y.H.1
Kim, J.2
Aoyama, T.3
-
81
-
-
84938093088
-
Hepatocyte nicotinamide adenine dinucleotide phosphate reduced oxidase 4 regulates stress signaling, fibrosis, and insulin sensitivity during development of steatohepatitis in mice
-
Bettaieb A, Jiang JX, Sasaki Y, et al. Hepatocyte nicotinamide adenine dinucleotide phosphate reduced oxidase 4 regulates stress signaling, fibrosis, and insulin sensitivity during development of steatohepatitis in mice. Gastroenterology. 2015;149:468 e410–480 e410.
-
(2015)
Gastroenterology
, vol.149
, pp. 468 e410-480 e410
-
-
Bettaieb, A.1
Jiang, J.X.2
Sasaki, Y.3
-
82
-
-
0142151769
-
Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression
-
COI: 1:CAS:528:DC%2BD3sXpsVOntrs%3D, PID: 14578857
-
Canbay A, Feldstein AE, Higuchi H, et al. Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression. Hepatology. 2003;38:1188–1198.
-
(2003)
Hepatology
, vol.38
, pp. 1188-1198
-
-
Canbay, A.1
Feldstein, A.E.2
Higuchi, H.3
-
83
-
-
1242336980
-
Apoptosis: the nexus of liver injury and fibrosis
-
PID: 14767974
-
Canbay A, Friedman S, Gores GJ. Apoptosis: the nexus of liver injury and fibrosis. Hepatology. 2004;39:273–278.
-
(2004)
Hepatology
, vol.39
, pp. 273-278
-
-
Canbay, A.1
Friedman, S.2
Gores, G.J.3
-
84
-
-
84861012202
-
Oxidative stress and benefits of antioxidant agents in acute and chronic hepatitis
-
PID: 22550523
-
Esrefoglu M. Oxidative stress and benefits of antioxidant agents in acute and chronic hepatitis. Hepat Mon. 2012;12:160–167.
-
(2012)
Hepat Mon
, vol.12
, pp. 160-167
-
-
Esrefoglu, M.1
-
85
-
-
0032171410
-
Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide
-
COI: 1:CAS:528:DyaK1cXlslKgsbw%3D, PID: 9741578
-
Squadrito GL, Pryor WA. Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide. Free Radic Biol Med. 1998;25:392–403.
-
(1998)
Free Radic Biol Med
, vol.25
, pp. 392-403
-
-
Squadrito, G.L.1
Pryor, W.A.2
-
86
-
-
0029037495
-
The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide
-
COI: 1:CAS:528:DyaK2MXlvVaisb4%3D, PID: 7762673
-
Pryor WA, Squadrito GL. The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am J Physiol. 1995;268:L699–L722.
-
(1995)
Am J Physiol
, vol.268
, pp. L699-L722
-
-
Pryor, W.A.1
Squadrito, G.L.2
-
87
-
-
33846863589
-
Nitric oxide and peroxynitrite in health and disease
-
COI: 1:CAS:528:DC%2BD2sXitVagsr8%3D, PID: 17237348
-
Pacher P, Beckman JS, Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol Rev. 2007;87:315–424.
-
(2007)
Physiol Rev
, vol.87
, pp. 315-424
-
-
Pacher, P.1
Beckman, J.S.2
Liaudet, L.3
-
88
-
-
0036893739
-
Enhanced intrahepatic inducible nitric oxide synthase expression and nitrotyrosine accumulation in primary biliary cirrhosis and autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BD38XoslCjtLg%3D, PID: 12445411
-
Sanz-Cameno P, Medina J, Garcia-Buey L, et al. Enhanced intrahepatic inducible nitric oxide synthase expression and nitrotyrosine accumulation in primary biliary cirrhosis and autoimmune hepatitis. J Hepatol. 2002;37:723–729.
-
(2002)
J Hepatol
, vol.37
, pp. 723-729
-
-
Sanz-Cameno, P.1
Medina, J.2
Garcia-Buey, L.3
-
89
-
-
33646788424
-
Nitrotyrosine and chlorotyrosine: clinical significance and biological functions in the vascular system
-
COI: 1:CAS:528:DC%2BD28XkvVGjurw%3D, PID: 16360172
-
Mohiuddin I, Chai H, Lin PH, et al. Nitrotyrosine and chlorotyrosine: clinical significance and biological functions in the vascular system. J Surg Res. 2006;133:143–149.
-
(2006)
J Surg Res
, vol.133
, pp. 143-149
-
-
Mohiuddin, I.1
Chai, H.2
Lin, P.H.3
-
90
-
-
14644401128
-
S-Nitrosothiols: cellular formation and transport
-
COI: 1:CAS:528:DC%2BD2MXitVCns7Y%3D, PID: 15749378
-
Zhang Y, Hogg N. S-Nitrosothiols: cellular formation and transport. Free Radic Biol Med. 2005;38:831–838.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 831-838
-
-
Zhang, Y.1
Hogg, N.2
-
91
-
-
84901379933
-
Functional roles of protein nitration in acute and chronic liver diseases
-
PID: 24876909
-
Abdelmegeed MA, Song BJ. Functional roles of protein nitration in acute and chronic liver diseases. Oxid Med Cell Longev. 2014;2014:149627.
-
(2014)
Oxid Med Cell Longev
, vol.2014
, pp. 149627
-
-
Abdelmegeed, M.A.1
Song, B.J.2
-
92
-
-
84918551836
-
Mitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modifications
-
COI: 1:CAS:528:DC%2BC2cXhvVGitL%2FE, PID: 25465468
-
Song BJ, Akbar M, Abdelmegeed MA, et al. Mitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modifications. Redox Biol. 2014;3:109–123.
-
(2014)
Redox Biol
, vol.3
, pp. 109-123
-
-
Song, B.J.1
Akbar, M.2
Abdelmegeed, M.A.3
-
93
-
-
84921345496
-
Nitric oxide is a potential mediator of hepatic inflammation and fibrogenesis in autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BC2MXht1KltL8%3D, PID: 25495215
-
Beyazit Y, Efe C, Tanoglu A, et al. Nitric oxide is a potential mediator of hepatic inflammation and fibrogenesis in autoimmune hepatitis. Scand J Gastroenterol. 2015;50:204–210.
-
(2015)
Scand J Gastroenterol
, vol.50
, pp. 204-210
-
-
Beyazit, Y.1
Efe, C.2
Tanoglu, A.3
-
94
-
-
84929505243
-
Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, is raised by health promoting factors
-
COI: 1:CAS:528:DC%2BC2MXhtVKrtb%2FI, PID: 25672622
-
Pall ML, Levine S. Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, is raised by health promoting factors. Sheng Li Xue Bao. 2015;67:1–18.
-
(2015)
Sheng Li Xue Bao
, vol.67
, pp. 1-18
-
-
Pall, M.L.1
Levine, S.2
-
95
-
-
77950994646
-
Autophagy: cellular and molecular mechanisms
-
COI: 1:CAS:528:DC%2BC3cXntFyjs7g%3D, PID: 20225336
-
Glick D, Barth S, Macleod KF. Autophagy: cellular and molecular mechanisms. J Pathol. 2010;221:3–12.
-
(2010)
J Pathol
, vol.221
, pp. 3-12
-
-
Glick, D.1
Barth, S.2
Macleod, K.F.3
-
96
-
-
84958854210
-
Alleviation mechanisms against hepatocyte oxidative stress in patients with chronic hepatic disorders
-
COI: 1:CAS:528:DC%2BC2MXhvVyiurnL, PID: 25581125
-
Hiura M, Honma Y, Miyagawa K, et al. Alleviation mechanisms against hepatocyte oxidative stress in patients with chronic hepatic disorders. Hepatol Res. 2015;45:1124–1135.
-
(2015)
Hepatol Res
, vol.45
, pp. 1124-1135
-
-
Hiura, M.1
Honma, Y.2
Miyagawa, K.3
-
97
-
-
22244446505
-
The mammalian unfolded protein response
-
PID: 15952902
-
Schroder M, Kaufman RJ. The mammalian unfolded protein response. Annu Rev Biochem. 2005;74:739–789.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 739-789
-
-
Schroder, M.1
Kaufman, R.J.2
-
98
-
-
84883387793
-
Targeting the unfolded protein response in disease
-
COI: 1:CAS:528:DC%2BC3sXhtlCgt7jL, PID: 23989796
-
Hetz C, Chevet E, Harding HP. Targeting the unfolded protein response in disease. Nat Rev Drug Discov. 2013;12:703–719.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 703-719
-
-
Hetz, C.1
Chevet, E.2
Harding, H.P.3
-
99
-
-
0029925880
-
Actions of cytokines on the immune response and viral interactions: an overview
-
COI: 1:CAS:528:DyaK28XisFygtLo%3D, PID: 8666349
-
Peters M. Actions of cytokines on the immune response and viral interactions: an overview. Hepatology. 1996;23:909–916.
-
(1996)
Hepatology
, vol.23
, pp. 909-916
-
-
Peters, M.1
-
100
-
-
31544469229
-
3. Cytokines and chemokines
-
COI: 1:CAS:528:DC%2BD28XhtV2ku7k%3D, PID: 16455343
-
Steinke JW, Borish L. 3. Cytokines and chemokines. J Allergy Clin Immunol. 2006;117:S441–S445.
-
(2006)
J Allergy Clin Immunol
, vol.117
, pp. S441-S445
-
-
Steinke, J.W.1
Borish, L.2
-
101
-
-
84862271549
-
Cytokines and HCV-related disorders
-
PID: 22611419
-
Fallahi P, Ferri C, Ferrari SM, et al. Cytokines and HCV-related disorders. Clin Dev Immunol. 2012;2012:468107.
-
(2012)
Clin Dev Immunol
, vol.2012
, pp. 468107
-
-
Fallahi, P.1
Ferri, C.2
Ferrari, S.M.3
-
102
-
-
0033874108
-
Proinflammatory cytokines
-
COI: 1:CAS:528:DC%2BD3cXmtlSms7s%3D, PID: 10936147
-
Dinarello CA. Proinflammatory cytokines. Chest. 2000;118:503–508.
-
(2000)
Chest
, vol.118
, pp. 503-508
-
-
Dinarello, C.A.1
-
103
-
-
31944433741
-
TGF-beta/Smad signaling in the injured liver
-
COI: 1:CAS:528:DC%2BD28XjtFentrs%3D, PID: 16397841
-
Breitkopf K, Godoy P, Ciuclan L, Singer MV, Dooley S. TGF-beta/Smad signaling in the injured liver. Z Gastroenterol. 2006;44:57–66.
-
(2006)
Z Gastroenterol
, vol.44
, pp. 57-66
-
-
Breitkopf, K.1
Godoy, P.2
Ciuclan, L.3
Singer, M.V.4
Dooley, S.5
-
104
-
-
84859445823
-
TGF-beta in progression of liver disease
-
COI: 1:CAS:528:DC%2BC38XkslCjsA%3D%3D, PID: 22006249
-
Dooley S, ten Dijke P. TGF-beta in progression of liver disease. Cell Tissue Res. 2012;347:245–256.
-
(2012)
Cell Tissue Res
, vol.347
, pp. 245-256
-
-
Dooley, S.1
ten Dijke, P.2
-
105
-
-
79953752559
-
Suppression of innate immunity (natural killer cell/interferon-gamma) in the advanced stages of liver fibrosis in mice
-
COI: 1:CAS:528:DC%2BC3MXktl2jt7Y%3D, PID: 21480338
-
Jeong WI, Park O, Suh YG, et al. Suppression of innate immunity (natural killer cell/interferon-gamma) in the advanced stages of liver fibrosis in mice. Hepatology. 2011;53:1342–1351.
-
(2011)
Hepatology
, vol.53
, pp. 1342-1351
-
-
Jeong, W.I.1
Park, O.2
Suh, Y.G.3
-
106
-
-
76049113956
-
The most severe forms of type I autoimmune hepatitis are associated with genetically determined levels of TGF-beta1
-
COI: 1:CAS:528:DC%2BC3cXitVOhu74%3D, PID: 19962351
-
Paladino N, Flores AC, Fainboim H, et al. The most severe forms of type I autoimmune hepatitis are associated with genetically determined levels of TGF-beta1. Clin Immunol. 2010;134:305–312.
-
(2010)
Clin Immunol
, vol.134
, pp. 305-312
-
-
Paladino, N.1
Flores, A.C.2
Fainboim, H.3
-
107
-
-
77953891627
-
Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice
-
COI: 1:CAS:528:DC%2BC3cXpsFaitb0%3D, PID: 20347818
-
Miura K, Kodama Y, Inokuchi S, et al. Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. Gastroenterology. 2010;139:323–334.
-
(2010)
Gastroenterology
, vol.139
, pp. 323-334
-
-
Miura, K.1
Kodama, Y.2
Inokuchi, S.3
-
108
-
-
84884984479
-
Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice
-
COI: 1:CAS:528:DC%2BC2MXhtl2mur%2FJ, PID: 23553591
-
Pradere JP, Kluwe J, De Minicis S, et al. Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice. Hepatology. 2013;58:1461–1473.
-
(2013)
Hepatology
, vol.58
, pp. 1461-1473
-
-
Pradere, J.P.1
Kluwe, J.2
De Minicis, S.3
-
109
-
-
84865461464
-
Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice
-
Meng F, Wang K, Aoyama T, et al. Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice. Gastroenterology. 2012;143:765–776 e761–763.
-
Gastroenterology. 2012;143
, vol.765-776
, pp. e761-e763
-
-
Meng, F.1
Wang, K.2
Aoyama, T.3
-
110
-
-
84906940502
-
IL-20 and IL-20R1 antibodies protect against liver fibrosis
-
COI: 1:CAS:528:DC%2BC2cXhsVGhtbvL, PID: 24763901
-
Chiu YS, Wei CC, Lin YJ, Hsu YH, Chang MS. IL-20 and IL-20R1 antibodies protect against liver fibrosis. Hepatology. 2014;60:1003–1014.
-
(2014)
Hepatology
, vol.60
, pp. 1003-1014
-
-
Chiu, Y.S.1
Wei, C.C.2
Lin, Y.J.3
Hsu, Y.H.4
Chang, M.S.5
-
111
-
-
84867176929
-
IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice
-
COI: 1:CAS:528:DC%2BC38XhsV2itrfO, PID: 22945633
-
Petrasek J, Bala S, Csak T, et al. IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice. J Clin Invest. 2012;122:3476–3489.
-
(2012)
J Clin Invest
, vol.122
, pp. 3476-3489
-
-
Petrasek, J.1
Bala, S.2
Csak, T.3
-
112
-
-
84865564349
-
Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice
-
COI: 1:CAS:528:DC%2BC38Xht1Kit7vO, PID: 22473749
-
Kong X, Feng D, Wang H, et al. Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice. Hepatology. 2012;56:1150–1159.
-
(2012)
Hepatology
, vol.56
, pp. 1150-1159
-
-
Kong, X.1
Feng, D.2
Wang, H.3
-
113
-
-
84866376202
-
The role of chemokines in acute liver injury
-
COI: 1:CAS:528:DC%2BC38XhtVenu7bN, PID: 22723782
-
Saiman Y, Friedman SL. The role of chemokines in acute liver injury. Front Physiol. 2012;3:213.
-
(2012)
Front Physiol
, vol.3
, pp. 213
-
-
Saiman, Y.1
Friedman, S.L.2
-
114
-
-
67651156353
-
CCR2 promotes hepatic fibrosis in mice
-
COI: 1:CAS:528:DC%2BD1MXpt1Shsbs%3D, PID: 19441102
-
Seki E, de Minicis S, Inokuchi S, et al. CCR2 promotes hepatic fibrosis in mice. Hepatology. 2009;50:185–197.
-
(2009)
Hepatology
, vol.50
, pp. 185-197
-
-
Seki, E.1
de Minicis, S.2
Inokuchi, S.3
-
115
-
-
78049415469
-
Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice
-
COI: 1:CAS:528:DC%2BC3cXhsVWgtbnO, PID: 20978355
-
Berres ML, Koenen RR, Rueland A, et al. Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice. J Clin Invest. 2010;120:4129–4140.
-
(2010)
J Clin Invest
, vol.120
, pp. 4129-4140
-
-
Berres, M.L.1
Koenen, R.R.2
Rueland, A.3
-
116
-
-
84960110717
-
Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR Phase 2b study design
-
PID: 26944023
-
Friedman S, Sanyal A, Goodman Z, et al. Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR Phase 2b study design. Contemp Clin Trials. 2016;47:356–365.
-
(2016)
Contemp Clin Trials
, vol.47
, pp. 356-365
-
-
Friedman, S.1
Sanyal, A.2
Goodman, Z.3
-
117
-
-
84943398334
-
The effects of Maraviroc on liver fibrosis in HIV/HCV co-infected patients
-
PID: 25394147
-
Gonzalez EO, Boix V, Deltoro MG, et al. The effects of Maraviroc on liver fibrosis in HIV/HCV co-infected patients. J Int AIDS Soc. 2014;17:19643.
-
(2014)
J Int AIDS Soc
, vol.17
, pp. 19643
-
-
Gonzalez, E.O.1
Boix, V.2
Deltoro, M.G.3
-
118
-
-
84943410555
-
Maraviroc: a review of its use in HIV infection and beyond
-
PID: 26491256
-
Woollard SM, Kanmogne GD. Maraviroc: a review of its use in HIV infection and beyond. Drug Des Devel Ther. 2015;9:5447–5468.
-
(2015)
Drug Des Devel Ther
, vol.9
, pp. 5447-5468
-
-
Woollard, S.M.1
Kanmogne, G.D.2
-
119
-
-
77956189184
-
Prevalence of vitamin D deficiency in chronic liver disease
-
COI: 1:CAS:528:DC%2BC3cXpslWrsLs%3D, PID: 19960254
-
Arteh J, Narra S, Nair S. Prevalence of vitamin D deficiency in chronic liver disease. Dig Dis Sci. 2010;55:2624–2628.
-
(2010)
Dig Dis Sci
, vol.55
, pp. 2624-2628
-
-
Arteh, J.1
Narra, S.2
Nair, S.3
-
120
-
-
84912532963
-
Low serum vitamin D levels are associated with severe histological features and poor response to therapy in patients with autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BC2cXhtFCqsbrL, PID: 25002309
-
Efe C, Kav T, Aydin C, et al. Low serum vitamin D levels are associated with severe histological features and poor response to therapy in patients with autoimmune hepatitis. Dig Dis Sci. 2014;59:3035–3042.
-
(2014)
Dig Dis Sci
, vol.59
, pp. 3035-3042
-
-
Efe, C.1
Kav, T.2
Aydin, C.3
-
121
-
-
84873731007
-
Vitamin D in chronic liver disease
-
COI: 1:CAS:528:DC%2BC3sXltV2ru7k%3D, PID: 23402606
-
Stokes CS, Volmer DA, Grunhage F, Lammert F. Vitamin D in chronic liver disease. Liver Int. 2013;33:338–352.
-
(2013)
Liver Int
, vol.33
, pp. 338-352
-
-
Stokes, C.S.1
Volmer, D.A.2
Grunhage, F.3
Lammert, F.4
-
122
-
-
84967224417
-
Correlation between vitamin D levels and apoptosis in geriatric patients infected with hepatitis C virus genotype 4
-
PID: 27217734
-
Gabr SA, Alghadir AH, Allam AA, et al. Correlation between vitamin D levels and apoptosis in geriatric patients infected with hepatitis C virus genotype 4. Clin Interv Aging. 2016;11:523–533.
-
(2016)
Clin Interv Aging
, vol.11
, pp. 523-533
-
-
Gabr, S.A.1
Alghadir, A.H.2
Allam, A.A.3
-
123
-
-
80655127773
-
Vitamin D inhibits proliferation and profibrotic marker expression in hepatic stellate cells and decreases thioacetamide-induced liver fibrosis in rats
-
COI: 1:CAS:528:DC%2BC38XmsFCktg%3D%3D, PID: 21816960
-
Abramovitch S, Dahan-Bachar L, Sharvit E, et al. Vitamin D inhibits proliferation and profibrotic marker expression in hepatic stellate cells and decreases thioacetamide-induced liver fibrosis in rats. Gut. 2011;60:1728–1737.
-
(2011)
Gut
, vol.60
, pp. 1728-1737
-
-
Abramovitch, S.1
Dahan-Bachar, L.2
Sharvit, E.3
-
124
-
-
84886946222
-
Vitamin D in autoimmune liver disease
-
COI: 1:CAS:528:DC%2BC3sXhtVOrt7nM, PID: 23845396
-
Smyk DS, Orfanidou T, Invernizzi P, Bogdanos DP, Lenzi M. Vitamin D in autoimmune liver disease. Clin Res Hepatol Gastroenterol. 2013;37:535–545.
-
(2013)
Clin Res Hepatol Gastroenterol
, vol.37
, pp. 535-545
-
-
Smyk, D.S.1
Orfanidou, T.2
Invernizzi, P.3
Bogdanos, D.P.4
Lenzi, M.5
-
125
-
-
84905584696
-
Vitamin D modulates biliary fibrosis in ABCB4-deficient mice
-
PID: 25191532
-
Hochrath K, Stokes CS, Geisel J, et al. Vitamin D modulates biliary fibrosis in ABCB4-deficient mice. Hepatol Int. 2014;8:443–452.
-
(2014)
Hepatol Int
, vol.8
, pp. 443-452
-
-
Hochrath, K.1
Stokes, C.S.2
Geisel, J.3
-
126
-
-
84928885304
-
Spontaneous liver fibrosis induced by long term dietary vitamin D deficiency in adult mice is related to chronic inflammation and enhanced apoptosis
-
COI: 1:CAS:528:DC%2BC2MXmslGgu7s%3D, PID: 25894394
-
Zhu L, Kong M, Han YP, et al. Spontaneous liver fibrosis induced by long term dietary vitamin D deficiency in adult mice is related to chronic inflammation and enhanced apoptosis. Can J Physiol Pharmacol. 2015;93:385–394.
-
(2015)
Can J Physiol Pharmacol
, vol.93
, pp. 385-394
-
-
Zhu, L.1
Kong, M.2
Han, Y.P.3
-
127
-
-
84876928036
-
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response
-
COI: 1:CAS:528:DC%2BC3sXmslehtrk%3D, PID: 23622244
-
Ding N, Yu RT, Subramaniam N, et al. A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response. Cell. 2013;153:601–613.
-
(2013)
Cell
, vol.153
, pp. 601-613
-
-
Ding, N.1
Yu, R.T.2
Subramaniam, N.3
-
128
-
-
74449083191
-
Vitamin D inhibition of pro-fibrotic effects of transforming growth factor beta1 in lung fibroblasts and epithelial cells
-
COI: 1:CAS:528:DC%2BC3cXhtVejsbo%3D, PID: 19931390
-
Ramirez AM, Wongtrakool C, Welch T, et al. Vitamin D inhibition of pro-fibrotic effects of transforming growth factor beta1 in lung fibroblasts and epithelial cells. J Steroid Biochem Mol Biol. 2010;118:142–150.
-
(2010)
J Steroid Biochem Mol Biol
, vol.118
, pp. 142-150
-
-
Ramirez, A.M.1
Wongtrakool, C.2
Welch, T.3
-
129
-
-
76749119362
-
1,25(OH)2vitamin D3 inhibits cell proliferation by promoting cell cycle arrest without inducing apoptosis and modifies cell morphology of mesenchymal multipotent cells
-
COI: 1:CAS:528:DC%2BC3cXitlSjur8%3D, PID: 20064609
-
Artaza JN, Sirad F, Ferrini MG, Norris KC. 1,25(OH)2vitamin D3 inhibits cell proliferation by promoting cell cycle arrest without inducing apoptosis and modifies cell morphology of mesenchymal multipotent cells. J Steroid Biochem Mol Biol. 2010;119:73–83.
-
(2010)
J Steroid Biochem Mol Biol
, vol.119
, pp. 73-83
-
-
Artaza, J.N.1
Sirad, F.2
Ferrini, M.G.3
Norris, K.C.4
-
130
-
-
84876087225
-
1,25-dihydroxyvitamin D3 and its nuclear receptor repress human alpha1 (I) collagen expression and type I collagen formation
-
COI: 1:CAS:528:DC%2BC3sXnsl2qtr0%3D, PID: 23413886
-
Potter JJ, Liu X, Koteish A, Mezey E. 1,25-dihydroxyvitamin D3 and its nuclear receptor repress human alpha1 (I) collagen expression and type I collagen formation. Liver Int. 2013;33:677–686.
-
(2013)
Liver Int
, vol.33
, pp. 677-686
-
-
Potter, J.J.1
Liu, X.2
Koteish, A.3
Mezey, E.4
-
131
-
-
67449150170
-
Vitamin D reduces the expression of collagen and key profibrotic factors by inducing an antifibrotic phenotype in mesenchymal multipotent cells
-
COI: 1:CAS:528:DC%2BD1MXjvVOguro%3D, PID: 19036760
-
Artaza JN, Norris KC. Vitamin D reduces the expression of collagen and key profibrotic factors by inducing an antifibrotic phenotype in mesenchymal multipotent cells. J Endocrinol. 2009;200:207–221.
-
(2009)
J Endocrinol
, vol.200
, pp. 207-221
-
-
Artaza, J.N.1
Norris, K.C.2
-
132
-
-
0036139687
-
Genetic association of vitamin D receptor polymorphisms with primary biliary cirrhosis and autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BD38XmvFaqtw%3D%3D, PID: 11786968
-
Vogel A, Strassburg CP, Manns MP. Genetic association of vitamin D receptor polymorphisms with primary biliary cirrhosis and autoimmune hepatitis. Hepatology. 2002;35:126–131.
-
(2002)
Hepatology
, vol.35
, pp. 126-131
-
-
Vogel, A.1
Strassburg, C.P.2
Manns, M.P.3
-
133
-
-
14844331387
-
Genetic association of vitamin D receptor polymorphisms with autoimmune hepatitis and primary biliary cirrhosis in the Chinese
-
COI: 1:CAS:528:DC%2BD2MXivFKlsrg%3D, PID: 15683428
-
Fan L, Tu X, Zhu Y, et al. Genetic association of vitamin D receptor polymorphisms with autoimmune hepatitis and primary biliary cirrhosis in the Chinese. J Gastroenterol Hepatol. 2005;20:249–255.
-
(2005)
J Gastroenterol Hepatol
, vol.20
, pp. 249-255
-
-
Fan, L.1
Tu, X.2
Zhu, Y.3
-
134
-
-
84986320302
-
Liganded vitamin D receptor through its interacting repressor inhibits the expression of type I collagen alpha1
-
Wan LY, Zhang YQ, Li JM, et al. Liganded vitamin D receptor through its interacting repressor inhibits the expression of type I collagen alpha1. DNA Cell Biol. 2016. doi:10.1089/dna.2016.3367.
-
(2016)
DNA Cell Biol
-
-
Wan, L.Y.1
Zhang, Y.Q.2
Li, J.M.3
-
135
-
-
0032146551
-
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
-
COI: 1:CAS:528:DyaK1cXlt1egur8%3D, PID: 9691091
-
Iredale JP, Benyon RC, Pickering J, et al. Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest. 1998;102:538–549.
-
(1998)
J Clin Invest
, vol.102
, pp. 538-549
-
-
Iredale, J.P.1
Benyon, R.C.2
Pickering, J.3
-
136
-
-
0035083958
-
Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors
-
COI: 1:CAS:528:DC%2BD3MXislyhurY%3D, PID: 11247901
-
Issa R, Williams E, Trim N, et al. Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors. Gut. 2001;48:548–557.
-
(2001)
Gut
, vol.48
, pp. 548-557
-
-
Issa, R.1
Williams, E.2
Trim, N.3
-
137
-
-
0033818244
-
Angiotensin II activates collagen I gene through a mechanism involving the MAP/ER kinase pathway
-
COI: 1:CAS:528:DC%2BD3cXntV2gsbc%3D, PID: 10988260
-
Tharaux PL, Chatziantoniou C, Fakhouri F, Dussaule JC. Angiotensin II activates collagen I gene through a mechanism involving the MAP/ER kinase pathway. Hypertension. 2000;36:330–336.
-
(2000)
Hypertension
, vol.36
, pp. 330-336
-
-
Tharaux, P.L.1
Chatziantoniou, C.2
Fakhouri, F.3
Dussaule, J.C.4
-
138
-
-
0033855572
-
Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells
-
COI: 1:CAS:528:DC%2BD3cXmtVWrurY%3D, PID: 10930382
-
Marra F, Efsen E, Romanelli RG, et al. Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells. Gastroenterology. 2000;119:466–478.
-
(2000)
Gastroenterology
, vol.119
, pp. 466-478
-
-
Marra, F.1
Efsen, E.2
Romanelli, R.G.3
-
139
-
-
77953806617
-
Peroxisome proliferator-activated receptors gamma reverses hepatic nutritional fibrosis in mice and suppresses activation of hepatic stellate cells in vitro
-
COI: 1:CAS:528:DC%2BC3cXlsFKmsb4%3D, PID: 20156580
-
Yu J, Zhang S, Chu ES, et al. Peroxisome proliferator-activated receptors gamma reverses hepatic nutritional fibrosis in mice and suppresses activation of hepatic stellate cells in vitro. Int J Biochem Cell Biol. 2010;42:948–957.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 948-957
-
-
Yu, J.1
Zhang, S.2
Chu, E.S.3
-
140
-
-
21344472982
-
Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C
-
COI: 1:CAS:528:DC%2BD2MXms12nsbg%3D, PID: 15892090
-
Hezode C, Roudot-Thoraval F, Nguyen S, et al. Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C. Hepatology. 2005;42:63–71.
-
(2005)
Hepatology
, vol.42
, pp. 63-71
-
-
Hezode, C.1
Roudot-Thoraval, F.2
Nguyen, S.3
-
141
-
-
15744388722
-
Antifibrogenic role of the cannabinoid receptor CB2 in the liver
-
COI: 1:CAS:528:DC%2BD2MXivFWntb8%3D, PID: 15765409
-
Julien B, Grenard P, Teixeira-Clerc F, et al. Antifibrogenic role of the cannabinoid receptor CB2 in the liver. Gastroenterology. 2005;128:742–755.
-
(2005)
Gastroenterology
, vol.128
, pp. 742-755
-
-
Julien, B.1
Grenard, P.2
Teixeira-Clerc, F.3
-
142
-
-
81255188391
-
Tissue inhibitors of metalloproteinases
-
COI: 1:CAS:528:DC%2BC3MXhs1KhsbfO, PID: 22078297
-
Murphy G. Tissue inhibitors of metalloproteinases. Genome Biol. 2011;12:233.
-
(2011)
Genome Biol
, vol.12
, pp. 233
-
-
Murphy, G.1
-
143
-
-
0030030039
-
Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver
-
COI: 1:CAS:528:DyaK28XhvFCmtbY%3D, PID: 8608892
-
Benyon RC, Iredale JP, Goddard S, Winwood PJ, Arthur MJ. Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver. Gastroenterology. 1996;110:821–831.
-
(1996)
Gastroenterology
, vol.110
, pp. 821-831
-
-
Benyon, R.C.1
Iredale, J.P.2
Goddard, S.3
Winwood, P.J.4
Arthur, M.J.5
-
144
-
-
0030947446
-
Extracellular matrix deposition, lysyl oxidase expression, and myofibroblastic differentiation during the initial stages of cholestatic fibrosis in the rat
-
COI: 1:CAS:528:DyaK2sXktlOku7c%3D, PID: 9194853
-
Desmouliere A, Darby I, Costa AM, et al. Extracellular matrix deposition, lysyl oxidase expression, and myofibroblastic differentiation during the initial stages of cholestatic fibrosis in the rat. Lab Invest. 1997;76:765–778.
-
(1997)
Lab Invest
, vol.76
, pp. 765-778
-
-
Desmouliere, A.1
Darby, I.2
Costa, A.M.3
-
145
-
-
0033858063
-
Metalloproteinases and their inhibitors in liver fibrosis
-
COI: 1:CAS:528:DC%2BD3cXmtFyjtLc%3D, PID: 10915630
-
Arthur MJ, Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis. Am J Physiol Gastrointest Liver Physiol. 2000;279:G245–G249.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
, pp. G245-G249
-
-
Arthur, M.J.1
Fibrogenesis, I.I.2
-
146
-
-
0037192866
-
Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis
-
COI: 1:CAS:528:DC%2BD38Xis1Khu74%3D, PID: 11796725
-
Murphy FR, Issa R, Zhou X, et al. Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis. J Biol Chem. 2002;277:11069–11076.
-
(2002)
J Biol Chem
, vol.277
, pp. 11069-11076
-
-
Murphy, F.R.1
Issa, R.2
Zhou, X.3
-
148
-
-
2942622398
-
Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking
-
COI: 1:CAS:528:DC%2BD2cXlsFaqs7s%3D, PID: 15188175
-
Issa R, Zhou X, Constandinou CM, et al. Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking. Gastroenterology. 2004;126:1795–1808.
-
(2004)
Gastroenterology
, vol.126
, pp. 1795-1808
-
-
Issa, R.1
Zhou, X.2
Constandinou, C.M.3
-
149
-
-
77956425361
-
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
-
COI: 1:CAS:528:DC%2BC3cXhtFWksrvF, PID: 20818376
-
Barry-Hamilton V, Spangler R, Marshall D, et al. Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment. Nat Med. 2010;16:1009–1017.
-
(2010)
Nat Med
, vol.16
, pp. 1009-1017
-
-
Barry-Hamilton, V.1
Spangler, R.2
Marshall, D.3
-
150
-
-
0031866404
-
Identification of a glucocorticoid response element in the human transforming growth factor beta 1 gene promoter
-
COI: 1:CAS:528:DyaK1cXks1Kluro%3D, PID: 9693962
-
Parrelli JM, Meisler N, Cutroneo KR. Identification of a glucocorticoid response element in the human transforming growth factor beta 1 gene promoter. Int J Biochem Cell Biol. 1998;30:623–627.
-
(1998)
Int J Biochem Cell Biol
, vol.30
, pp. 623-627
-
-
Parrelli, J.M.1
Meisler, N.2
Cutroneo, K.R.3
-
151
-
-
0033128865
-
Perspective article: transforming growth factor-beta: crossroad of glucocorticoid and bleomycin regulation of collagen synthesis in lung fibroblasts
-
COI: 1:STN:280:DyaK1MzkvVKgsg%3D%3D, PID: 10417748
-
Shukla A, Meisler N, Cutroneo KR. Perspective article: transforming growth factor-beta: crossroad of glucocorticoid and bleomycin regulation of collagen synthesis in lung fibroblasts. Wound Repair Regen. 1999;7:133–140.
-
(1999)
Wound Repair Regen
, vol.7
, pp. 133-140
-
-
Shukla, A.1
Meisler, N.2
Cutroneo, K.R.3
-
152
-
-
0025784444
-
Glucocorticoid regulation of transforming growth factor beta 1 activity and binding in osteoblast-enriched cultures from fetal rat bone
-
COI: 1:CAS:528:DyaK3MXlsFSqt7g%3D, PID: 1875934
-
Centrella M, McCarthy TL, Canalis E. Glucocorticoid regulation of transforming growth factor beta 1 activity and binding in osteoblast-enriched cultures from fetal rat bone. Mol Cell Biol. 1991;11:4490–4496.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 4490-4496
-
-
Centrella, M.1
McCarthy, T.L.2
Canalis, E.3
-
153
-
-
8844266275
-
Glucocorticoids decrease the bioavailability of TGF-beta which leads to a reduced TGF-beta signaling in hepatic stellate cells
-
COI: 1:CAS:528:DC%2BD2cXhtVSrsbzL, PID: 15555563
-
Bolkenius U, Hahn D, Gressner AM, et al. Glucocorticoids decrease the bioavailability of TGF-beta which leads to a reduced TGF-beta signaling in hepatic stellate cells. Biochem Biophys Res Commun. 2004;325:1264–1270.
-
(2004)
Biochem Biophys Res Commun
, vol.325
, pp. 1264-1270
-
-
Bolkenius, U.1
Hahn, D.2
Gressner, A.M.3
-
154
-
-
84867492451
-
Drug choices in autoimmune hepatitis: Part A - steroids
-
COI: 1:CAS:528:DC%2BC38XhsV2kurfO, PID: 23061711
-
Czaja AJ. Drug choices in autoimmune hepatitis: Part A - steroids. Expert Rev Gastroenterol Hepatol. 2012;6:603–615.
-
(2012)
Expert Rev Gastroenterol Hepatol
, vol.6
, pp. 603-615
-
-
Czaja, A.J.1
-
155
-
-
0029801742
-
Regulation of cytokine and cytokine receptor expression by glucocorticoids
-
COI: 1:CAS:528:DyaK28XntVCmt7k%3D, PID: 8929546
-
Almawi WY, Beyhum HN, Rahme AA, Rieder MJ. Regulation of cytokine and cytokine receptor expression by glucocorticoids. J Leukoc Biol. 1996;60:563–572.
-
(1996)
J Leukoc Biol
, vol.60
, pp. 563-572
-
-
Almawi, W.Y.1
Beyhum, H.N.2
Rahme, A.A.3
Rieder, M.J.4
-
156
-
-
0001853291
-
Molecular mechanisms of glucocorticoid effects
-
Almawi WY. Molecular mechanisms of glucocorticoid effects. Mod Asp Immunobiol. 2001;2:78–82.
-
(2001)
Mod Asp Immunobiol
, vol.2
, pp. 78-82
-
-
Almawi, W.Y.1
-
157
-
-
11844269814
-
Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids
-
COI: 1:CAS:528:DC%2BD2MXhsVeisLc%3D, PID: 15634032
-
Czock D, Keller F, Rasche FM, Haussler U. Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids. Clin Pharmacokinet. 2005;44:61–98.
-
(2005)
Clin Pharmacokinet
, vol.44
, pp. 61-98
-
-
Czock, D.1
Keller, F.2
Rasche, F.M.3
Haussler, U.4
-
158
-
-
0034284349
-
Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors
-
PID: 10969176
-
De Bosscher K, Vanden Berghe W, Haegeman G. Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors. J Neuroimmunol. 2000;109:16–22.
-
(2000)
J Neuroimmunol
, vol.109
, pp. 16-22
-
-
De Bosscher, K.1
Vanden Berghe, W.2
Haegeman, G.3
-
159
-
-
0031054279
-
Apoptosis induction in human peripheral blood T lymphocytes by high-dose steroid therapy
-
COI: 1:CAS:528:DyaK2sXhvFKru70%3D, PID: 9047155
-
Migita K, Eguchi K, Kawabe Y, et al. Apoptosis induction in human peripheral blood T lymphocytes by high-dose steroid therapy. Transplantation. 1997;63:583–587.
-
(1997)
Transplantation
, vol.63
, pp. 583-587
-
-
Migita, K.1
Eguchi, K.2
Kawabe, Y.3
-
161
-
-
79954780467
-
Oltipraz therapy in patients with liver fibrosis or cirrhosis: a randomized, double-blind, placebo-controlled phase II trial
-
COI: 1:CAS:528:DC%2BC3MXlvFKrtbw%3D, PID: 21492164
-
Kim SG, Kim YM, Choi JY, et al. Oltipraz therapy in patients with liver fibrosis or cirrhosis: a randomized, double-blind, placebo-controlled phase II trial. J Pharm Pharmacol. 2011;63:627–635.
-
(2011)
J Pharm Pharmacol
, vol.63
, pp. 627-635
-
-
Kim, S.G.1
Kim, Y.M.2
Choi, J.Y.3
-
162
-
-
85022157598
-
Validation of serum fibrosis panels in patients with primary sclerosing cholangitis (PSC) in a randomized trial of Simtuzumab (Abstract)
-
Bowlus CL, Patel K, Guha IH, et al. Validation of serum fibrosis panels in patients with primary sclerosing cholangitis (PSC) in a randomized trial of Simtuzumab (Abstract). Hepatology. 2015;62:519A.
-
(2015)
Hepatology
, vol.62
, pp. 519A
-
-
Bowlus, C.L.1
Patel, K.2
Guha, I.H.3
-
163
-
-
84885396184
-
Angiotensin II facilitates fibrogenic effect of TGF-beta1 through enhancing the down-regulation of BAMBI caused by LPS: a new pro-fibrotic mechanism of angiotensin II
-
COI: 1:CAS:528:DC%2BC3sXhs1KitbbL, PID: 24155898
-
Li YS, Ni SY, Meng Y, et al. Angiotensin II facilitates fibrogenic effect of TGF-beta1 through enhancing the down-regulation of BAMBI caused by LPS: a new pro-fibrotic mechanism of angiotensin II. PLoS One. 2013;8:e76289.
-
(2013)
PLoS One
, vol.8
-
-
Li, Y.S.1
Ni, S.Y.2
Meng, Y.3
-
164
-
-
84957617612
-
Angiotensin-converting enzyme for noninvasive assessment of liver fibrosis in autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BC2MXnsFOksb4%3D, PID: 25860719
-
Efe C, Cengiz M, Kahramanoglu-Aksoy E, et al. Angiotensin-converting enzyme for noninvasive assessment of liver fibrosis in autoimmune hepatitis. Eur J Gastroenterol Hepatol. 2015;27:649–654.
-
(2015)
Eur J Gastroenterol Hepatol
, vol.27
, pp. 649-654
-
-
Efe, C.1
Cengiz, M.2
Kahramanoglu-Aksoy, E.3
-
165
-
-
84949995737
-
Angiotensin-converting enzyme gene polymorphism (insertion/deletion) and liver fibrosis in Turkish patients from the western Black Sea region, Turkey
-
COI: 1:CAS:528:DC%2BC28XhtFals7nN, PID: 26681055
-
Turhan NK, Ilikhan SU, Hamamcioglu AC, et al. Angiotensin-converting enzyme gene polymorphism (insertion/deletion) and liver fibrosis in Turkish patients from the western Black Sea region, Turkey. Genet Mol Res. 2015;14:17079–17090.
-
(2015)
Genet Mol Res
, vol.14
, pp. 17079-17090
-
-
Turhan, N.K.1
Ilikhan, S.U.2
Hamamcioglu, A.C.3
-
166
-
-
0036906034
-
Biochemical markers of liver fibrosis in patients infected by hepatitis C virus: longitudinal validation in a randomized trial
-
COI: 1:STN:280:DC%2BD383ktFGrsA%3D%3D, PID: 11876795
-
Poynard T, Imbert-Bismut F, Ratziu V, et al. Biochemical markers of liver fibrosis in patients infected by hepatitis C virus: longitudinal validation in a randomized trial. J Viral Hepat. 2002;9:128–133.
-
(2002)
J Viral Hepat
, vol.9
, pp. 128-133
-
-
Poynard, T.1
Imbert-Bismut, F.2
Ratziu, V.3
-
167
-
-
0042265556
-
A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C
-
PID: 12883497
-
Wai CT, Greenson JK, Fontana RJ, et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology. 2003;38:518–526.
-
(2003)
Hepatology
, vol.38
, pp. 518-526
-
-
Wai, C.T.1
Greenson, J.K.2
Fontana, R.J.3
-
168
-
-
84884416525
-
Simple noninvasive systems predict long-term outcomes of patients with nonalcoholic fatty liver disease
-
PID: 23860502
-
Angulo P, Bugianesi E, Bjornsson ES, et al. Simple noninvasive systems predict long-term outcomes of patients with nonalcoholic fatty liver disease. Gastroenterology. 2013;145:782–789.
-
(2013)
Gastroenterology
, vol.145
, pp. 782-789
-
-
Angulo, P.1
Bugianesi, E.2
Bjornsson, E.S.3
-
169
-
-
33745547388
-
Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection
-
COI: 1:CAS:528:DC%2BD28XmsF2nur0%3D, PID: 16729309
-
Sterling RK, Lissen E, Clumeck N, et al. Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology. 2006;43:1317–1325.
-
(2006)
Hepatology
, vol.43
, pp. 1317-1325
-
-
Sterling, R.K.1
Lissen, E.2
Clumeck, N.3
-
170
-
-
34547483053
-
FIB-4: an inexpensive and accurate marker of fibrosis in HCV infection. Comparison with liver biopsy and fibrotest
-
COI: 1:CAS:528:DC%2BD2sXosVyltrg%3D, PID: 17567829
-
Vallet-Pichard A, Mallet V, Nalpas B, et al. FIB-4: an inexpensive and accurate marker of fibrosis in HCV infection. Comparison with liver biopsy and fibrotest. Hepatology. 2007;46:32–36.
-
(2007)
Hepatology
, vol.46
, pp. 32-36
-
-
Vallet-Pichard, A.1
Mallet, V.2
Nalpas, B.3
-
171
-
-
58149305616
-
The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B
-
COI: 1:STN:280:DC%2BD1M%2FlvFaisA%3D%3D, PID: 19035983
-
Mallet V, Dhalluin-Venier V, Roussin C, et al. The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B. Aliment Pharmacol Ther. 2009;29:409–415.
-
(2009)
Aliment Pharmacol Ther
, vol.29
, pp. 409-415
-
-
Mallet, V.1
Dhalluin-Venier, V.2
Roussin, C.3
-
172
-
-
70349546276
-
Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease
-
COI: 1:CAS:528:DC%2BD1MXhsFaqtbnK, PID: 19523535
-
Shah AG, Lydecker A, Murray K, et al. Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2009;7:1104–1112.
-
(2009)
Clin Gastroenterol Hepatol
, vol.7
, pp. 1104-1112
-
-
Shah, A.G.1
Lydecker, A.2
Murray, K.3
-
173
-
-
39549118158
-
Noninvasive markers of fibrosis in nonalcoholic fatty liver disease: validating the European Liver Fibrosis Panel and exploring simple markers
-
PID: 18038452
-
Guha IN, Parkes J, Roderick P, et al. Noninvasive markers of fibrosis in nonalcoholic fatty liver disease: validating the European Liver Fibrosis Panel and exploring simple markers. Hepatology. 2008;47:455–460.
-
(2008)
Hepatology
, vol.47
, pp. 455-460
-
-
Guha, I.N.1
Parkes, J.2
Roderick, P.3
-
174
-
-
77956110546
-
Enhanced liver fibrosis test can predict clinical outcomes in patients with chronic liver disease
-
COI: 1:CAS:528:DC%2BC3cXht1yhtr7I, PID: 20675693
-
Parkes J, Roderick P, Harris S, et al. Enhanced liver fibrosis test can predict clinical outcomes in patients with chronic liver disease. Gut. 2010;59:1245–1251.
-
(2010)
Gut
, vol.59
, pp. 1245-1251
-
-
Parkes, J.1
Roderick, P.2
Harris, S.3
-
175
-
-
77956111847
-
Enhanced Liver Fibrosis (ELF) test accurately identifies liver fibrosis in patients with chronic hepatitis C
-
COI: 1:STN:280:DC%2BC3M%2FmvFertg%3D%3D, PID: 20196799
-
Parkes J, Guha IN, Roderick P, et al. Enhanced Liver Fibrosis (ELF) test accurately identifies liver fibrosis in patients with chronic hepatitis C. J Viral Hepat. 2011;18:23–31.
-
(2011)
J Viral Hepat
, vol.18
, pp. 23-31
-
-
Parkes, J.1
Guha, I.N.2
Roderick, P.3
-
176
-
-
53849131691
-
Biomarkers of liver fibrosis
-
COI: 1:CAS:528:DC%2BD1cXhsVOqsLrL, PID: 19004189
-
Poynard T, Morra R, Ingiliz P, et al. Biomarkers of liver fibrosis. Adv Clin Chem. 2008;46:131–160.
-
(2008)
Adv Clin Chem
, vol.46
, pp. 131-160
-
-
Poynard, T.1
Morra, R.2
Ingiliz, P.3
-
177
-
-
79957467964
-
Noninvasive markers of hepatic fibrosis in chronic hepatitis B
-
PID: 21654911
-
Poynard T, Ngo Y, Munteanu M, Thabut D, Ratziu V. Noninvasive markers of hepatic fibrosis in chronic hepatitis B. Curr Hepat Rep. 2011;10:87–97.
-
(2011)
Curr Hepat Rep
, vol.10
, pp. 87-97
-
-
Poynard, T.1
Ngo, Y.2
Munteanu, M.3
Thabut, D.4
Ratziu, V.5
-
178
-
-
83155181614
-
FibroTest and Fibroscan performances revisited in patients with chronic hepatitis C. Impact of the spectrum effect and the applicability rate
-
PID: 21852224
-
Poynard T, de Ledinghen V, Zarski JP, et al. FibroTest and Fibroscan performances revisited in patients with chronic hepatitis C. Impact of the spectrum effect and the applicability rate. Clin Res Hepatol Gastroenterol. 2011;35:720–730.
-
(2011)
Clin Res Hepatol Gastroenterol
, vol.35
, pp. 720-730
-
-
Poynard, T.1
de Ledinghen, V.2
Zarski, J.P.3
-
179
-
-
84857360103
-
Relative performances of FibroTest, Fibroscan, and biopsy for the assessment of the stage of liver fibrosis in patients with chronic hepatitis C: a step toward the truth in the absence of a gold standard
-
PID: 21889468
-
Poynard T, de Ledinghen V, Zarski JP, et al. Relative performances of FibroTest, Fibroscan, and biopsy for the assessment of the stage of liver fibrosis in patients with chronic hepatitis C: a step toward the truth in the absence of a gold standard. J Hepatol. 2012;56:541–548.
-
(2012)
J Hepatol
, vol.56
, pp. 541-548
-
-
Poynard, T.1
de Ledinghen, V.2
Zarski, J.P.3
-
180
-
-
84865117303
-
Prognostic value of liver fibrosis biomarkers: a meta-analysis
-
Poynard T, Ngo Y, Perazzo H, et al. Prognostic value of liver fibrosis biomarkers: a meta-analysis. Gastroenterol Hepatol (NY). 2011;7:445–454.
-
(2011)
Gastroenterol Hepatol (NY)
, vol.7
, pp. 445-454
-
-
Poynard, T.1
Ngo, Y.2
Perazzo, H.3
-
181
-
-
84917677294
-
FibroScan (vibration-controlled transient elastography): where does it stand in the united states practice
-
PID: 24909907
-
Tapper EB, Castera L, Afdhal NH. FibroScan (vibration-controlled transient elastography): where does it stand in the united states practice. Clin Gastroenterol Hepatol. 2015;13:27–36.
-
(2015)
Clin Gastroenterol Hepatol
, vol.13
, pp. 27-36
-
-
Tapper, E.B.1
Castera, L.2
Afdhal, N.H.3
-
182
-
-
84874473244
-
Determination of reliability criteria for liver stiffness evaluation by transient elastography
-
PID: 22899556
-
Boursier J, Zarski JP, de Ledinghen V, et al. Determination of reliability criteria for liver stiffness evaluation by transient elastography. Hepatology. 2013;57:1182–1191.
-
(2013)
Hepatology
, vol.57
, pp. 1182-1191
-
-
Boursier, J.1
Zarski, J.P.2
de Ledinghen, V.3
-
183
-
-
34748845382
-
Ultrasound-based transient elastography for the detection of hepatic fibrosis: systematic review and meta-analysis
-
PID: 17916549
-
Talwalkar JA, Kurtz DM, Schoenleber SJ, West CP, Montori VM. Ultrasound-based transient elastography for the detection of hepatic fibrosis: systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2007;5:1214–1220.
-
(2007)
Clin Gastroenterol Hepatol
, vol.5
, pp. 1214-1220
-
-
Talwalkar, J.A.1
Kurtz, D.M.2
Schoenleber, S.J.3
West, C.P.4
Montori, V.M.5
-
184
-
-
41349094999
-
Performance of transient elastography for the staging of liver fibrosis: a meta-analysis
-
PID: 18395077
-
Friedrich-Rust M, Ong MF, Martens S, et al. Performance of transient elastography for the staging of liver fibrosis: a meta-analysis. Gastroenterology. 2008;134:960–974.
-
(2008)
Gastroenterology
, vol.134
, pp. 960-974
-
-
Friedrich-Rust, M.1
Ong, M.F.2
Martens, S.3
-
185
-
-
77649279553
-
A meta-analysis of transient elastography for the detection of hepatic fibrosis
-
PID: 19745758
-
Stebbing J, Farouk L, Panos G, et al. A meta-analysis of transient elastography for the detection of hepatic fibrosis. J Clin Gastroenterol. 2010;44:214–219.
-
(2010)
J Clin Gastroenterol
, vol.44
, pp. 214-219
-
-
Stebbing, J.1
Farouk, L.2
Panos, G.3
-
186
-
-
79952694689
-
Elastography for the diagnosis of severity of fibrosis in chronic liver disease: a meta-analysis of diagnostic accuracy
-
COI: 1:STN:280:DC%2BC3M3ns1KhtA%3D%3D, PID: 21146892
-
Tsochatzis EA, Gurusamy KS, Ntaoula S, et al. Elastography for the diagnosis of severity of fibrosis in chronic liver disease: a meta-analysis of diagnostic accuracy. J Hepatol. 2011;54:650–659.
-
(2011)
J Hepatol
, vol.54
, pp. 650-659
-
-
Tsochatzis, E.A.1
Gurusamy, K.S.2
Ntaoula, S.3
-
187
-
-
84887995212
-
Liver stiffness is associated with risk of decompensation, liver cancer, and death in patients with chronic liver diseases: a systematic review and meta-analysis
-
PID: 23954643
-
Singh S, Fujii LL, Murad MH, et al. Liver stiffness is associated with risk of decompensation, liver cancer, and death in patients with chronic liver diseases: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2013;11:1573–1584.
-
(2013)
Clin Gastroenterol Hepatol
, vol.11
, pp. 1573-1584
-
-
Singh, S.1
Fujii, L.L.2
Murad, M.H.3
-
188
-
-
39549105171
-
Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damage
-
COI: 1:CAS:528:DC%2BD1cXitF2lu74%3D, PID: 18098325
-
Sagir A, Erhardt A, Schmitt M, Haussinger D. Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damage. Hepatology. 2008;47:592–595.
-
(2008)
Hepatology
, vol.47
, pp. 592-595
-
-
Sagir, A.1
Erhardt, A.2
Schmitt, M.3
Haussinger, D.4
-
189
-
-
58149083313
-
Alanine aminotransferase-based algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B
-
PID: 18673426
-
Chan HL, Wong GL, Choi PC, et al. Alanine aminotransferase-based algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B. J Viral Hepat. 2009;16:36–44.
-
(2009)
J Viral Hepat
, vol.16
, pp. 36-44
-
-
Chan, H.L.1
Wong, G.L.2
Choi, P.C.3
-
190
-
-
75149148751
-
How can we enhance the performance of liver stiffness measurement using FibroScan in diagnosing liver cirrhosis in patients with chronic hepatitis B?
-
PID: 19609218
-
Kim SU, do Kim Y, Park JY, et al. How can we enhance the performance of liver stiffness measurement using FibroScan in diagnosing liver cirrhosis in patients with chronic hepatitis B? J Clin Gastroenterol. 2010;44:66–71.
-
(2010)
J Clin Gastroenterol
, vol.44
, pp. 66-71
-
-
Kim, S.U.1
do Kim, Y.2
Park, J.Y.3
-
191
-
-
84959322567
-
Usefulness of liver stiffness measurement during acute cellular rejection in liver transplantation
-
PID: 26609794
-
Crespo G, Castro-Narro G, Garcia-Juarez I, et al. Usefulness of liver stiffness measurement during acute cellular rejection in liver transplantation. Liver Transpl. 2016;22:298–304.
-
(2016)
Liver Transpl
, vol.22
, pp. 298-304
-
-
Crespo, G.1
Castro-Narro, G.2
Garcia-Juarez, I.3
-
192
-
-
48949086333
-
Disproportionally high results of transient elastography in patients with autoimmune hepatitis
-
PID: 18783552
-
Romanque P, Stickel F, Dufour JF. Disproportionally high results of transient elastography in patients with autoimmune hepatitis. Liver Int. 2008;28:1177–1178.
-
(2008)
Liver Int
, vol.28
, pp. 1177-1178
-
-
Romanque, P.1
Stickel, F.2
Dufour, J.F.3
-
193
-
-
84884532167
-
Acoustic radiation force impulse and supersonic shear imaging versus transient elastography for liver fibrosis assessment
-
PID: 23932281
-
Sporea I, Bota S, Jurchis A, et al. Acoustic radiation force impulse and supersonic shear imaging versus transient elastography for liver fibrosis assessment. Ultrasound Med Biol. 2013;39:1933–1941.
-
(2013)
Ultrasound Med Biol
, vol.39
, pp. 1933-1941
-
-
Sporea, I.1
Bota, S.2
Jurchis, A.3
-
194
-
-
44949148177
-
Safety issues in the management of autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BD1cXlsFCmurc%3D, PID: 18462189
-
Czaja AJ. Safety issues in the management of autoimmune hepatitis. Expert Opin Drug Saf. 2008;7:319–333.
-
(2008)
Expert Opin Drug Saf
, vol.7
, pp. 319-333
-
-
Czaja, A.J.1
-
195
-
-
70249130127
-
Liver fibrosis in viral hepatitis: noninvasive assessment with acoustic radiation force impulse imaging versus transient elastography
-
PID: 19703889
-
Friedrich-Rust M, Wunder K, Kriener S, et al. Liver fibrosis in viral hepatitis: noninvasive assessment with acoustic radiation force impulse imaging versus transient elastography. Radiology. 2009;252:595–604.
-
(2009)
Radiology
, vol.252
, pp. 595-604
-
-
Friedrich-Rust, M.1
Wunder, K.2
Kriener, S.3
-
196
-
-
79951473084
-
Acoustic Radiation Force Impulse (ARFI)—a new modality for the evaluation of liver fibrosis
-
PID: 21165451
-
Sporea I, Sirli R, Popescu A, Danila M. Acoustic Radiation Force Impulse (ARFI)—a new modality for the evaluation of liver fibrosis. Med Ultrason. 2010;12:26–31.
-
(2010)
Med Ultrason
, vol.12
, pp. 26-31
-
-
Sporea, I.1
Sirli, R.2
Popescu, A.3
Danila, M.4
-
197
-
-
84881552256
-
Meta-analysis: ARFI elastography versus transient elastography for the evaluation of liver fibrosis
-
PID: 23859217
-
Bota S, Herkner H, Sporea I, et al. Meta-analysis: ARFI elastography versus transient elastography for the evaluation of liver fibrosis. Liver Int. 2013;33:1138–1147.
-
(2013)
Liver Int
, vol.33
, pp. 1138-1147
-
-
Bota, S.1
Herkner, H.2
Sporea, I.3
-
198
-
-
84870236416
-
ARFI elastography in patients with chronic autoimmune liver diseases: a preliminary study
-
COI: 1:STN:280:DC%2BC3snptlWgtg%3D%3D, PID: 23730386
-
Righi S, Fiorini E, De Molo C, et al. ARFI elastography in patients with chronic autoimmune liver diseases: a preliminary study. J Ultrasound. 2012;15:226–231.
-
(2012)
J Ultrasound
, vol.15
, pp. 226-231
-
-
Righi, S.1
Fiorini, E.2
De Molo, C.3
-
199
-
-
84964694113
-
Acoustic Radiation Force Impulse (ARFI) for fibrosis staging in patients with autoimmune hepatitis
-
PID: 26897951
-
Efe C, Gungoren MS, Ozaslan E, Akbiyik F, Kav T. Acoustic Radiation Force Impulse (ARFI) for fibrosis staging in patients with autoimmune hepatitis. Hepatogastroenterology. 2015;62:670–672.
-
(2015)
Hepatogastroenterology
, vol.62
, pp. 670-672
-
-
Efe, C.1
Gungoren, M.S.2
Ozaslan, E.3
Akbiyik, F.4
Kav, T.5
-
200
-
-
84882249291
-
The influence of aminotransferase levels on liver stiffness assessed by Acoustic Radiation Force Impulse Elastography: a retrospective multicentre study
-
COI: 1:CAS:528:DC%2BC3sXktlGnsrY%3D, PID: 23510533
-
Bota S, Sporea I, Peck-Radosavljevic M, et al. The influence of aminotransferase levels on liver stiffness assessed by Acoustic Radiation Force Impulse Elastography: a retrospective multicentre study. Dig Liver Dis. 2013;45:762–768.
-
(2013)
Dig Liver Dis
, vol.45
, pp. 762-768
-
-
Bota, S.1
Sporea, I.2
Peck-Radosavljevic, M.3
-
201
-
-
84873527067
-
Factors which influence the accuracy of acoustic radiation force impulse (ARFI) elastography for the diagnosis of liver fibrosis in patients with chronic hepatitis C
-
PID: 23245820
-
Bota S, Sporea I, Sirli R, Popescu A, Jurchis A. Factors which influence the accuracy of acoustic radiation force impulse (ARFI) elastography for the diagnosis of liver fibrosis in patients with chronic hepatitis C. Ultrasound Med Biol. 2013;39:407–412.
-
(2013)
Ultrasound Med Biol
, vol.39
, pp. 407-412
-
-
Bota, S.1
Sporea, I.2
Sirli, R.3
Popescu, A.4
Jurchis, A.5
-
202
-
-
85027943357
-
Evaluation of liver fibrosis by transient elastography using acoustic radiation force impulse: comparison with Fibroscan((R))
-
PID: 21779759
-
Ebinuma H, Saito H, Komuta M, et al. Evaluation of liver fibrosis by transient elastography using acoustic radiation force impulse: comparison with Fibroscan((R)). J Gastroenterol. 2011;46:1238–1248.
-
(2011)
J Gastroenterol
, vol.46
, pp. 1238-1248
-
-
Ebinuma, H.1
Saito, H.2
Komuta, M.3
-
203
-
-
84863102127
-
Head-to-head comparison of transient elastography (TE), real-time tissue elastography (RTE), and acoustic radiation force impulse (ARFI) imaging in the diagnosis of liver fibrosis
-
PID: 22223175
-
Colombo S, Buonocore M, Del Poggio A, et al. Head-to-head comparison of transient elastography (TE), real-time tissue elastography (RTE), and acoustic radiation force impulse (ARFI) imaging in the diagnosis of liver fibrosis. J Gastroenterol. 2012;47:461–469.
-
(2012)
J Gastroenterol
, vol.47
, pp. 461-469
-
-
Colombo, S.1
Buonocore, M.2
Del Poggio, A.3
-
204
-
-
46049100990
-
Magnetic resonance elastography for the noninvasive staging of liver fibrosis
-
PID: 18471441
-
Huwart L, Sempoux C, Vicaut E, et al. Magnetic resonance elastography for the noninvasive staging of liver fibrosis. Gastroenterology. 2008;135:32–40.
-
(2008)
Gastroenterology
, vol.135
, pp. 32-40
-
-
Huwart, L.1
Sempoux, C.2
Vicaut, E.3
-
205
-
-
84874226671
-
Magnetic resonance elastography of liver: technique, analysis, and clinical applications
-
PID: 23423795
-
Venkatesh SK, Yin M, Ehman RL. Magnetic resonance elastography of liver: technique, analysis, and clinical applications. J Magn Reson Imaging. 2013;37:544–555.
-
(2013)
J Magn Reson Imaging
, vol.37
, pp. 544-555
-
-
Venkatesh, S.K.1
Yin, M.2
Ehman, R.L.3
-
206
-
-
84889061107
-
Magnetic resonance elastography of liver: clinical applications
-
PID: 24270110
-
Venkatesh SK, Yin M, Ehman RL. Magnetic resonance elastography of liver: clinical applications. J Comput Assist Tomogr. 2013;37:887–896.
-
(2013)
J Comput Assist Tomogr
, vol.37
, pp. 887-896
-
-
Venkatesh, S.K.1
Yin, M.2
Ehman, R.L.3
-
207
-
-
67650341226
-
Feasibility of in vivo MR elastographic splenic stiffness measurements in the assessment of portal hypertension
-
Talwalkar JA, Yin M, Venkatesh S, et al. Feasibility of in vivo MR elastographic splenic stiffness measurements in the assessment of portal hypertension. Am J Roentgenol. 2009;193:122–127.
-
(2009)
Am J Roentgenol
, vol.193
, pp. 122-127
-
-
Talwalkar, J.A.1
Yin, M.2
Venkatesh, S.3
-
209
-
-
80054757186
-
MR elastography for noninvasive assessment of hepatic fibrosis: experience from a tertiary center in Asia
-
PID: 21932355
-
Kim BH, Lee JM, Lee YJ, et al. MR elastography for noninvasive assessment of hepatic fibrosis: experience from a tertiary center in Asia. J Magn Reson Imaging. 2011;34:1110–1116.
-
(2011)
J Magn Reson Imaging
, vol.34
, pp. 1110-1116
-
-
Kim, B.H.1
Lee, J.M.2
Lee, Y.J.3
-
211
-
-
84911948591
-
Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study
-
COI: 1:CAS:528:DC%2BC2cXitVCis7%2FK, PID: 25103310
-
Loomba R, Wolfson T, Ang B, et al. Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study. Hepatology. 2014;60:1920–1928.
-
(2014)
Hepatology
, vol.60
, pp. 1920-1928
-
-
Loomba, R.1
Wolfson, T.2
Ang, B.3
-
212
-
-
84956713473
-
Magnetic resonance elastography is superior to acoustic radiation force impulse for the diagnosis of fibrosis in patients with biopsy-proven nonalcoholic fatty liver disease: a prospective study
-
PID: 26560734
-
Cui J, Heba E, Hernandez C, et al. Magnetic resonance elastography is superior to acoustic radiation force impulse for the diagnosis of fibrosis in patients with biopsy-proven nonalcoholic fatty liver disease: a prospective study. Hepatology. 2016;63:453–461.
-
(2016)
Hepatology
, vol.63
, pp. 453-461
-
-
Cui, J.1
Heba, E.2
Hernandez, C.3
-
213
-
-
84959449613
-
Magnetic resonance imaging more accurately classifies steatosis and fibrosis in patients with nonalcoholic fatty liver disease than transient elastography
-
Imajo K, Kessoku T, Honda Y, et al. Magnetic resonance imaging more accurately classifies steatosis and fibrosis in patients with nonalcoholic fatty liver disease than transient elastography. Gastroenterology. 2016;150:626–637 e627.
-
Gastroenterology. 2016;150
, vol.626-637
, pp. e627
-
-
Imajo, K.1
Kessoku, T.2
Honda, Y.3
-
214
-
-
84874574154
-
Translating an understanding of the pathogenesis of hepatic fibrosis to novel therapies
-
Rockey DC. Translating an understanding of the pathogenesis of hepatic fibrosis to novel therapies. Clin Gastroenterol Hepatol. 2013;11:224–231 e225.
-
Clin Gastroenterol Hepatol. 2013;11
, vol.224-231
, pp. e225
-
-
Rockey, D.C.1
-
216
-
-
84911126301
-
The role of oxidative stress in the development of alcoholic liver disease
-
COI: 1:STN:280:DC%2BC2cjmtVShug%3D%3D, PID: 24861526
-
Galicia-Moreno M, Gutierrez-Reyes G. The role of oxidative stress in the development of alcoholic liver disease. Rev Gastroenterol Mex. 2014;79:135–144.
-
(2014)
Rev Gastroenterol Mex
, vol.79
, pp. 135-144
-
-
Galicia-Moreno, M.1
Gutierrez-Reyes, G.2
-
217
-
-
84926420371
-
Alcoholic liver disease: mechanisms of injury and targeted treatment
-
PID: 25782093
-
Louvet A, Mathurin P. Alcoholic liver disease: mechanisms of injury and targeted treatment. Nat Rev Gastroenterol Hepatol. 2015;12:231–242.
-
(2015)
Nat Rev Gastroenterol Hepatol
, vol.12
, pp. 231-242
-
-
Louvet, A.1
Mathurin, P.2
-
218
-
-
79956301571
-
The role of oxidative stress in non-alcoholic steatohepatitis
-
COI: 1:CAS:528:DC%2BC3MXmslOltb0%3D, PID: 21514287
-
Koek GH, Liedorp PR, Bast A. The role of oxidative stress in non-alcoholic steatohepatitis. Clin Chim Acta. 2011;412:1297–1305.
-
(2011)
Clin Chim Acta
, vol.412
, pp. 1297-1305
-
-
Koek, G.H.1
Liedorp, P.R.2
Bast, A.3
-
219
-
-
84885945197
-
Involvement of free radicals and oxidative stress in NAFLD/NASH
-
COI: 1:CAS:528:DC%2BC3sXhs1SmurrO, PID: 24004441
-
Sumida Y, Niki E, Naito Y, Yoshikawa T. Involvement of free radicals and oxidative stress in NAFLD/NASH. Free Radic Res. 2013;47:869–880.
-
(2013)
Free Radic Res
, vol.47
, pp. 869-880
-
-
Sumida, Y.1
Niki, E.2
Naito, Y.3
Yoshikawa, T.4
-
220
-
-
84937590608
-
Antioxidant mechanisms in nonalcoholic fatty liver disease
-
COI: 1:CAS:528:DC%2BC2MXhslGitbbN, PID: 25915484
-
Liu W, Baker SS, Baker RD, Zhu L. Antioxidant mechanisms in nonalcoholic fatty liver disease. Curr Drug Targets. 2015;16:1301–1314.
-
(2015)
Curr Drug Targets
, vol.16
, pp. 1301-1314
-
-
Liu, W.1
Baker, S.S.2
Baker, R.D.3
Zhu, L.4
-
221
-
-
84936766624
-
Serum levels of nitrate, nitrite and advanced oxidation protein products (AOPP) in patients with nonalcoholic fatty liver disease
-
COI: 1:STN:280:DC%2BC28%2FgvF2jsQ%3D%3D, PID: 26151688
-
Ciftci A, Yilmaz B, Koklu S, et al. Serum levels of nitrate, nitrite and advanced oxidation protein products (AOPP) in patients with nonalcoholic fatty liver disease. Acta Gastroenterol Belg. 2015;78:201–205.
-
(2015)
Acta Gastroenterol Belg
, vol.78
, pp. 201-205
-
-
Ciftci, A.1
Yilmaz, B.2
Koklu, S.3
-
222
-
-
33645819203
-
Mechanisms of liver injury. III. Oxidative stress in the pathogenesis of hepatitis C virus
-
COI: 1:CAS:528:DC%2BD28XkvFKls7g%3D, PID: 16603728
-
Choi J, Ou JH. Mechanisms of liver injury. III. Oxidative stress in the pathogenesis of hepatitis C virus. Am J Physiol Gastrointest Liver Physiol. 2006;290:G847–G851.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
, pp. G847-G851
-
-
Choi, J.1
Ou, J.H.2
-
223
-
-
84901358645
-
Oxidative stress and hepatic Nox proteins in chronic hepatitis C and hepatocellular carcinoma
-
COI: 1:CAS:528:DC%2BC2cXpslOjt74%3D, PID: 24816297
-
Choi J, Corder NL, Koduru B, Wang Y. Oxidative stress and hepatic Nox proteins in chronic hepatitis C and hepatocellular carcinoma. Free Radic Biol Med. 2014;72:267–284.
-
(2014)
Free Radic Biol Med
, vol.72
, pp. 267-284
-
-
Choi, J.1
Corder, N.L.2
Koduru, B.3
Wang, Y.4
-
224
-
-
3242812768
-
Oxidant stress in type I autoimmune hepatitis: the link between necroinflammation and fibrogenesis?
-
COI: 1:CAS:528:DC%2BD2cXmtVSqtL4%3D, PID: 15276644
-
Pemberton PW, Aboutwerat A, Smith A, et al. Oxidant stress in type I autoimmune hepatitis: the link between necroinflammation and fibrogenesis? Biochim Biophys Acta. 2004;1689:182–189.
-
(2004)
Biochim Biophys Acta
, vol.1689
, pp. 182-189
-
-
Pemberton, P.W.1
Aboutwerat, A.2
Smith, A.3
-
225
-
-
1842584604
-
A murine model of type 2 autoimmune hepatitis: xenoimmunization with human antigens
-
COI: 1:CAS:528:DC%2BD2cXjtlCqs7o%3D, PID: 15057911
-
Lapierre P, Djilali-Saiah I, Vitozzi S, Alvarez F. A murine model of type 2 autoimmune hepatitis: xenoimmunization with human antigens. Hepatology. 2004;39:1066–1074.
-
(2004)
Hepatology
, vol.39
, pp. 1066-1074
-
-
Lapierre, P.1
Djilali-Saiah, I.2
Vitozzi, S.3
Alvarez, F.4
-
226
-
-
45149109642
-
Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection
-
COI: 1:CAS:528:DC%2BD1cXntFant74%3D, PID: 18474629
-
Holdener M, Hintermann E, Bayer M, et al. Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection. J Exp Med. 2008;205:1409–1422.
-
(2008)
J Exp Med
, vol.205
, pp. 1409-1422
-
-
Holdener, M.1
Hintermann, E.2
Bayer, M.3
-
227
-
-
77955257434
-
Animal models of autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BC3cXpsF2ltbw%3D, PID: 20678017
-
Czaja AJ. Animal models of autoimmune hepatitis. Expert Rev Gastroenterol Hepatol. 2010;4:429–443.
-
(2010)
Expert Rev Gastroenterol Hepatol
, vol.4
, pp. 429-443
-
-
Czaja, A.J.1
-
228
-
-
0344867846
-
S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial
-
COI: 1:CAS:528:DyaK1MXktFems7k%3D, PID: 10406187
-
Mato JM, Camara J, Fernandez de Paz J, et al. S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial. J Hepatol. 1999;30:1081–1089.
-
(1999)
J Hepatol
, vol.30
, pp. 1081-1089
-
-
Mato, J.M.1
Camara, J.2
Fernandez de Paz, J.3
-
229
-
-
79952311505
-
S-adenosyl methionine improves early viral responses and interferon-stimulated gene induction in hepatitis C nonresponders
-
COI: 1:CAS:528:DC%2BC3MXjs1Wks7g%3D, PID: 20854821
-
Feld JJ, Modi AA, El-Diwany R, et al. S-adenosyl methionine improves early viral responses and interferon-stimulated gene induction in hepatitis C nonresponders. Gastroenterology. 2011;140:830–839.
-
(2011)
Gastroenterology
, vol.140
, pp. 830-839
-
-
Feld, J.J.1
Modi, A.A.2
El-Diwany, R.3
-
230
-
-
0344742265
-
Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis
-
COI: 1:CAS:528:DC%2BD3sXpt1Sgu7k%3D, PID: 14638353
-
Harrison SA, Torgerson S, Hayashi P, Ward J, Schenker S. Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis. Am J Gastroenterol. 2003;98:2485–2490.
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 2485-2490
-
-
Harrison, S.A.1
Torgerson, S.2
Hayashi, P.3
Ward, J.4
Schenker, S.5
-
231
-
-
77951874018
-
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis
-
COI: 1:CAS:528:DC%2BC3cXls1Oltr4%3D, PID: 20427778
-
Sanyal AJ, Chalasani N, Kowdley KV, et al. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med. 2010;362:1675–1685.
-
(2010)
N Engl J Med
, vol.362
, pp. 1675-1685
-
-
Sanyal, A.J.1
Chalasani, N.2
Kowdley, K.V.3
-
232
-
-
23444439192
-
Effects of N-acetylcysteine on ethanol-induced hepatotoxicity in rats fed via total enteral nutrition
-
COI: 1:CAS:528:DC%2BD2MXns1Whsr8%3D, PID: 16085180
-
Ronis MJ, Butura A, Sampey BP, et al. Effects of N-acetylcysteine on ethanol-induced hepatotoxicity in rats fed via total enteral nutrition. Free Radic Biol Med. 2005;39:619–630.
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 619-630
-
-
Ronis, M.J.1
Butura, A.2
Sampey, B.P.3
-
233
-
-
33644882812
-
Antioxidants versus corticosteroids in the treatment of severe alcoholic hepatitis–a randomised clinical trial
-
COI: 1:CAS:528:DC%2BD28XisFyqtLk%3D, PID: 16469404
-
Phillips M, Curtis H, Portmann B, et al. Antioxidants versus corticosteroids in the treatment of severe alcoholic hepatitis–a randomised clinical trial. J Hepatol. 2006;44:784–790.
-
(2006)
J Hepatol
, vol.44
, pp. 784-790
-
-
Phillips, M.1
Curtis, H.2
Portmann, B.3
-
234
-
-
34347401402
-
A randomized trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis
-
COI: 1:CAS:528:DC%2BD2sXnsFKgurk%3D, PID: 17532088
-
Stewart S, Prince M, Bassendine M, et al. A randomized trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis. J Hepatol. 2007;47:277–283.
-
(2007)
J Hepatol
, vol.47
, pp. 277-283
-
-
Stewart, S.1
Prince, M.2
Bassendine, M.3
-
235
-
-
80955166935
-
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis
-
COI: 1:CAS:528:DC%2BC3MXhsF2ks7jM, PID: 22070475
-
Nguyen-Khac E, Thevenot T, Piquet MA, et al. Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. N Engl J Med. 2011;365:1781–1789.
-
(2011)
N Engl J Med
, vol.365
, pp. 1781-1789
-
-
Nguyen-Khac, E.1
Thevenot, T.2
Piquet, M.A.3
-
236
-
-
33847378451
-
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis
-
COI: 1:CAS:528:DC%2BD2sXisVSgt7o%3D, PID: 17327526
-
Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA. 2007;297:842–857.
-
(2007)
JAMA
, vol.297
, pp. 842-857
-
-
Bjelakovic, G.1
Nikolova, D.2
Gluud, L.L.3
Simonetti, R.G.4
Gluud, C.5
-
237
-
-
77954338198
-
Meta-analysis: antioxidant supplements for liver diseases—the Cochrane Hepato-Biliary Group
-
COI: 1:STN:280:DC%2BC3cnnvVWisw%3D%3D, PID: 20497142
-
Bjelakovic G, Gluud LL, Nikolova D, et al. Meta-analysis: antioxidant supplements for liver diseases—the Cochrane Hepato-Biliary Group. Aliment Pharmacol Ther. 2010;32:356–367.
-
(2010)
Aliment Pharmacol Ther
, vol.32
, pp. 356-367
-
-
Bjelakovic, G.1
Gluud, L.L.2
Nikolova, D.3
-
238
-
-
70349804297
-
Nox proteins in signal transduction
-
COI: 1:CAS:528:DC%2BD1MXht1yjtbjI, PID: 19628035
-
Brown DI, Griendling KK. Nox proteins in signal transduction. Free Radic Biol Med. 2009;47:1239–1253.
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 1239-1253
-
-
Brown, D.I.1
Griendling, K.K.2
-
239
-
-
84891811928
-
An inhibitor of NADPH oxidase-4 attenuates established pulmonary fibrosis in a rodent disease model
-
PID: 23977848
-
Jarman ER, Khambata VS, Cope C, et al. An inhibitor of NADPH oxidase-4 attenuates established pulmonary fibrosis in a rodent disease model. Am J Respir Cell Mol Biol. 2014;50:158–169.
-
(2014)
Am J Respir Cell Mol Biol
, vol.50
, pp. 158-169
-
-
Jarman, E.R.1
Khambata, V.S.2
Cope, C.3
-
240
-
-
84862290446
-
Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo
-
COI: 1:CAS:528:DC%2BC38XpvVOqur8%3D, PID: 22618020
-
Jiang JX, Chen X, Serizawa N, et al. Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo. Free Radic Biol Med. 2012;53:289–296.
-
(2012)
Free Radic Biol Med
, vol.53
, pp. 289-296
-
-
Jiang, J.X.1
Chen, X.2
Serizawa, N.3
-
241
-
-
33646593852
-
Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells
-
COI: 1:CAS:528:DC%2BD28Xks1Slurg%3D, PID: 16227320
-
Sturrock A, Cahill B, Norman K, et al. Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2006;290:L661–L673.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
, pp. L661-L673
-
-
Sturrock, A.1
Cahill, B.2
Norman, K.3
-
242
-
-
55549098874
-
Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity
-
COI: 1:CAS:528:DC%2BD1cXhtl2qu7bL, PID: 18845355
-
Carmona-Cuenca I, Roncero C, Sancho P, et al. Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity. J Hepatol. 2008;49:965–976.
-
(2008)
J Hepatol
, vol.49
, pp. 965-976
-
-
Carmona-Cuenca, I.1
Roncero, C.2
Sancho, P.3
-
243
-
-
0036082554
-
Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542
-
COI: 1:CAS:528:DC%2BD38Xlt1KqtLc%3D, PID: 12065755
-
Laping NJ, Grygielko E, Mathur A, et al. Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542. Mol Pharmacol. 2002;62:58–64.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 58-64
-
-
Laping, N.J.1
Grygielko, E.2
Mathur, A.3
-
244
-
-
30944466813
-
Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis
-
COI: 1:CAS:528:DC%2BD28Xos1Crsw%3D%3D, PID: 16290023
-
Roberts AB, Tian F, Byfield SD, et al. Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis. Cytokine Growth Factor Rev. 2006;17:19–27.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 19-27
-
-
Roberts, A.B.1
Tian, F.2
Byfield, S.D.3
-
245
-
-
0032133353
-
Design of isoform-selective inhibitors of nitric oxide synthase
-
COI: 1:CAS:528:DyaK1cXmtFWnsr0%3D, PID: 9736922
-
Babu BR, Griffith OW. Design of isoform-selective inhibitors of nitric oxide synthase. Curr Opin Chem Biol. 1998;2:491–500.
-
(1998)
Curr Opin Chem Biol
, vol.2
, pp. 491-500
-
-
Babu, B.R.1
Griffith, O.W.2
-
246
-
-
33646169337
-
Selective inhibitors of inducible nitric oxide synthase: potential agents for the treatment of inflammatory diseases?
-
COI: 1:CAS:528:DC%2BD28XitVantrw%3D, PID: 16454760
-
Tinker AC, Wallace AV. Selective inhibitors of inducible nitric oxide synthase: potential agents for the treatment of inflammatory diseases? Curr Top Med Chem. 2006;6:77–92.
-
(2006)
Curr Top Med Chem
, vol.6
, pp. 77-92
-
-
Tinker, A.C.1
Wallace, A.V.2
-
247
-
-
54249114838
-
Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase
-
COI: 1:CAS:528:DC%2BD1cXht1Kgs7nM, PID: 18849972
-
Garcin ED, Arvai AS, Rosenfeld RJ, et al. Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat Chem Biol. 2008;4:700–707.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 700-707
-
-
Garcin, E.D.1
Arvai, A.S.2
Rosenfeld, R.J.3
-
248
-
-
61449263657
-
Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping
-
COI: 1:CAS:528:DC%2BD1MXktVOhtg%3D%3D, PID: 19125620
-
Ji H, Li H, Martasek P, et al. Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping. J Med Chem. 2009;52:779–797.
-
(2009)
J Med Chem
, vol.52
, pp. 779-797
-
-
Ji, H.1
Li, H.2
Martasek, P.3
-
249
-
-
84867817981
-
Arginine-based inhibitors of nitric oxide synthase: therapeutic potential and challenges
-
PID: 22988346
-
Vitecek J, Lojek A, Valacchi G, Kubala L. Arginine-based inhibitors of nitric oxide synthase: therapeutic potential and challenges. Mediators Inflamm. 2012;2012:318087.
-
(2012)
Mediators Inflamm
, vol.2012
, pp. 318087
-
-
Vitecek, J.1
Lojek, A.2
Valacchi, G.3
Kubala, L.4
-
250
-
-
77955279350
-
A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders
-
COI: 1:CAS:528:DC%2BC3cXpsFOntrg%3D, PID: 19799917
-
Kim J, Cha YN, Surh YJ. A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders. Mutat Res. 2010;690:12–23.
-
(2010)
Mutat Res
, vol.690
, pp. 12-23
-
-
Kim, J.1
Cha, Y.N.2
Surh, Y.J.3
-
251
-
-
84879090781
-
Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model
-
COI: 1:CAS:528:DC%2BC3sXhtVajsbjJ, PID: 23592516
-
Shimozono R, Asaoka Y, Yoshizawa Y, et al. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol Pharmacol. 2013;84:62–70.
-
(2013)
Mol Pharmacol
, vol.84
, pp. 62-70
-
-
Shimozono, R.1
Asaoka, Y.2
Yoshizawa, Y.3
-
252
-
-
4644328941
-
Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis
-
COI: 1:CAS:528:DC%2BD2cXnsFOltLs%3D, PID: 15374950
-
Iida K, Itoh K, Kumagai Y, et al. Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis. Cancer Res. 2004;64:6424–6431.
-
(2004)
Cancer Res
, vol.64
, pp. 6424-6431
-
-
Iida, K.1
Itoh, K.2
Kumagai, Y.3
-
253
-
-
0036884409
-
Oltipraz regenerates cirrhotic liver through CCAAT/enhancer binding protein-mediated stellate cell inactivation
-
COI: 1:CAS:528:DC%2BD38Xps1Ojsbw%3D, PID: 12397085
-
Kang KW, Kim YG, Cho MK, et al. Oltipraz regenerates cirrhotic liver through CCAAT/enhancer binding protein-mediated stellate cell inactivation. FASEB J. 2002;16:1988–1990.
-
(2002)
FASEB J
, vol.16
, pp. 1988-1990
-
-
Kang, K.W.1
Kim, Y.G.2
Cho, M.K.3
-
254
-
-
68949146859
-
Therapeutic potential of dithiolethiones for hepatic diseases
-
COI: 1:CAS:528:DC%2BD1MXhtVegsLrF, PID: 19563826
-
Brooks SC 3rd, Brooks JS, Lee WH, Lee MG, Kim SG. Therapeutic potential of dithiolethiones for hepatic diseases. Pharmacol Ther. 2009;124:31–43.
-
(2009)
Pharmacol Ther
, vol.124
, pp. 31-43
-
-
Brooks, S.C.1
Brooks, J.S.2
Lee, W.H.3
Lee, M.G.4
Kim, S.G.5
-
255
-
-
0034843656
-
Antifibrotic effect of silymarin in rat secondary biliary fibrosis is mediated by downregulation of procollagen alpha1(I) and TIMP-1
-
COI: 1:CAS:528:DC%2BD3MXnslKrsbg%3D, PID: 11592601
-
Jia JD, Bauer M, Cho JJ, et al. Antifibrotic effect of silymarin in rat secondary biliary fibrosis is mediated by downregulation of procollagen alpha1(I) and TIMP-1. J Hepatol. 2001;35:392–398.
-
(2001)
J Hepatol
, vol.35
, pp. 392-398
-
-
Jia, J.D.1
Bauer, M.2
Cho, J.J.3
-
256
-
-
84955270536
-
Silymarin in the treatment of liver diseases: what is the clinical evidence?
-
Ferenci P. Silymarin in the treatment of liver diseases: what is the clinical evidence? Clin Liver Dis. 2016;7:8–10.
-
(2016)
Clin Liver Dis
, vol.7
, pp. 8-10
-
-
Ferenci, P.1
-
257
-
-
0030796417
-
Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats
-
COI: 1:CAS:528:DyaK2sXmt1Cksbk%3D, PID: 9303494
-
Boigk G, Stroedter L, Herbst H, et al. Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats. Hepatology. 1997;26:643–649.
-
(1997)
Hepatology
, vol.26
, pp. 643-649
-
-
Boigk, G.1
Stroedter, L.2
Herbst, H.3
-
258
-
-
0029879066
-
Inhibition of Kupffer cell functions as an explanation for the hepatoprotective properties of silibinin
-
COI: 1:CAS:528:DyaK28XisFygtr0%3D, PID: 8666328
-
Dehmlow C, Erhard J, de Groot H. Inhibition of Kupffer cell functions as an explanation for the hepatoprotective properties of silibinin. Hepatology. 1996;23:749–754.
-
(1996)
Hepatology
, vol.23
, pp. 749-754
-
-
Dehmlow, C.1
Erhard, J.2
de Groot, H.3
-
259
-
-
34247583381
-
Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized Silymarin
-
COI: 1:CAS:528:DC%2BD2sXmsVymsLk%3D, PID: 17484885
-
Polyak SJ, Morishima C, Shuhart MC, et al. Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized Silymarin. Gastroenterology. 2007;132:1925–1936.
-
(2007)
Gastroenterology
, vol.132
, pp. 1925-1936
-
-
Polyak, S.J.1
Morishima, C.2
Shuhart, M.C.3
-
260
-
-
77950540443
-
Identification of hepatoprotective flavonolignans from silymarin
-
COI: 1:CAS:528:DC%2BC3cXks1KktL8%3D, PID: 20231449
-
Polyak SJ, Morishima C, Lohmann V, et al. Identification of hepatoprotective flavonolignans from silymarin. Proc Natl Acad Sci USA. 2010;107:5995–5999.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5995-5999
-
-
Polyak, S.J.1
Morishima, C.2
Lohmann, V.3
-
261
-
-
0024321992
-
Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver
-
COI: 1:STN:280:DyaL1MzmtVChtg%3D%3D, PID: 2671116
-
Ferenci P, Dragosics B, Dittrich H, et al. Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. J Hepatol. 1989;9:105–113.
-
(1989)
J Hepatol
, vol.9
, pp. 105-113
-
-
Ferenci, P.1
Dragosics, B.2
Dittrich, H.3
-
262
-
-
84858959526
-
Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial
-
COI: 1:CAS:528:DC%2BC38XmtlWgsLY%3D, PID: 22343419
-
Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med. 2012;52:1658–1665.
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 1658-1665
-
-
Loguercio, C.1
Andreone, P.2
Brisc, C.3
-
263
-
-
0031960861
-
Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial
-
COI: 1:CAS:528:DyaK1cXmvVWhtLo%3D, PID: 9566830
-
Pares A, Planas R, Torres M, et al. Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial. J Hepatol. 1998;28:615–621.
-
(1998)
J Hepatol
, vol.28
, pp. 615-621
-
-
Pares, A.1
Planas, R.2
Torres, M.3
-
264
-
-
0036151676
-
Effects of silymarin MZ-80 on oxidative stress in patients with alcoholic cirrhosis. Results of a randomized, double-blind, placebo-controlled clinical study
-
COI: 1:CAS:528:DC%2BD38Xht1ylur0%3D, PID: 11841050
-
Lucena MI, Andrade RJ, de la Cruz JP, et al. Effects of silymarin MZ-80 on oxidative stress in patients with alcoholic cirrhosis. Results of a randomized, double-blind, placebo-controlled clinical study. Int J Clin Pharmacol Ther. 2002;40:2–8.
-
(2002)
Int J Clin Pharmacol Ther
, vol.40
, pp. 2-8
-
-
Lucena, M.I.1
Andrade, R.J.2
de la Cruz, J.P.3
-
265
-
-
85035392112
-
Liver fibrosis
-
COI: 1:CAS:528:DC%2BD2MXhtFyjs70%3D, PID: 15690074
-
Bataller R, Brenner DA. Liver fibrosis. J Clin Invest. 2005;115:209–218.
-
(2005)
J Clin Invest
, vol.115
, pp. 209-218
-
-
Bataller, R.1
Brenner, D.A.2
-
266
-
-
0034961836
-
Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis
-
COI: 1:CAS:528:DC%2BD3MXlt1yktL4%3D, PID: 11438504
-
Jonsson JR, Clouston AD, Ando Y, et al. Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis. Gastroenterology. 2001;121:148–155.
-
(2001)
Gastroenterology
, vol.121
, pp. 148-155
-
-
Jonsson, J.R.1
Clouston, A.D.2
Ando, Y.3
-
267
-
-
0042168915
-
An angiotensin II type 1 receptor antagonist, olmesartan medoxomil, improves experimental liver fibrosis by suppression of proliferation and collagen synthesis in activated hepatic stellate cells
-
COI: 1:CAS:528:DC%2BD3sXmtFemt70%3D, PID: 12871826
-
Kurikawa N, Suga M, Kuroda S, Yamada K, Ishikawa H. An angiotensin II type 1 receptor antagonist, olmesartan medoxomil, improves experimental liver fibrosis by suppression of proliferation and collagen synthesis in activated hepatic stellate cells. Br J Pharmacol. 2003;139:1085–1094.
-
(2003)
Br J Pharmacol
, vol.139
, pp. 1085-1094
-
-
Kurikawa, N.1
Suga, M.2
Kuroda, S.3
Yamada, K.4
Ishikawa, H.5
-
268
-
-
70349756901
-
Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C
-
COI: 1:CAS:528:DC%2BD1MXhtlentr7K, PID: 19628656
-
Colmenero J, Bataller R, Sancho-Bru P, et al. Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C. Am J Physiol Gastrointest Liver Physiol. 2009;297:G726–G734.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.297
, pp. G726-G734
-
-
Colmenero, J.1
Bataller, R.2
Sancho-Bru, P.3
-
269
-
-
84969766998
-
Angiotensin-(1–7) Improves liver fibrosis by regulating the NLRP3 inflammasome via redox balance modulation
-
COI: 1:CAS:528:DC%2BC28XnvVCqt7c%3D, PID: 26728324
-
Cai SM, Yang RQ, Li Y, et al. Angiotensin-(1–7) Improves liver fibrosis by regulating the NLRP3 inflammasome via redox balance modulation. Antioxid Redox Signal. 2016;24:795–812.
-
(2016)
Antioxid Redox Signal
, vol.24
, pp. 795-812
-
-
Cai, S.M.1
Yang, R.Q.2
Li, Y.3
-
270
-
-
77950608186
-
Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats
-
COI: 1:CAS:528:DC%2BC3cXks1SqsLw%3D, PID: 20044807
-
Moreno M, Gonzalo T, Kok RJ, et al. Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats. Hepatology. 2010;51:942–952.
-
(2010)
Hepatology
, vol.51
, pp. 942-952
-
-
Moreno, M.1
Gonzalo, T.2
Kok, R.J.3
-
271
-
-
64749115204
-
The effect of angiotensin-blocking agents on liver fibrosis in patients with hepatitis C
-
COI: 1:CAS:528:DC%2BD1MXlvFSjurw%3D, PID: 19220742
-
Corey KE, Shah N, Misdraji J, et al. The effect of angiotensin-blocking agents on liver fibrosis in patients with hepatitis C. Liver Int. 2009;29:748–753.
-
(2009)
Liver Int
, vol.29
, pp. 748-753
-
-
Corey, K.E.1
Shah, N.2
Misdraji, J.3
-
272
-
-
77950618056
-
Angiotensin II antagonists in patients with recurrent hepatitis C virus infection after liver transplantation
-
PID: 19515217
-
Cholongitas E, Vibhakorn S, Lodato F, Burroughs AK. Angiotensin II antagonists in patients with recurrent hepatitis C virus infection after liver transplantation. Liver Int. 2010;30:334–335.
-
(2010)
Liver Int
, vol.30
, pp. 334-335
-
-
Cholongitas, E.1
Vibhakorn, S.2
Lodato, F.3
Burroughs, A.K.4
-
273
-
-
79952453566
-
The effects of angiotensin blocking agents on the progression of liver fibrosis in the HALT-C Trial cohort
-
COI: 1:CAS:528:DC%2BC3MXht1SrtrY%3D, PID: 21136163
-
Abu Dayyeh BK, Yang M, Dienstag JL, Chung RT. The effects of angiotensin blocking agents on the progression of liver fibrosis in the HALT-C Trial cohort. Dig Dis Sci. 2011;56:564–568.
-
(2011)
Dig Dis Sci
, vol.56
, pp. 564-568
-
-
Abu Dayyeh, B.K.1
Yang, M.2
Dienstag, J.L.3
Chung, R.T.4
-
274
-
-
84896315255
-
Simtuzumab, an antifibrotic monoclonal antibody against lysyl-oxidase-like 2 (LOXL2) enzyme, appears safe and well tolerated in patients with liver disease of diverse etiology (Abstract)
-
Tahal AH, Feron-Rigodon M, Madere J, Subramanian GM, Bornstein JD. Simtuzumab, an antifibrotic monoclonal antibody against lysyl-oxidase-like 2 (LOXL2) enzyme, appears safe and well tolerated in patients with liver disease of diverse etiology (Abstract). J Hepatol. 2013;53:S532.
-
(2013)
J Hepatol
, vol.53
, pp. S532
-
-
Tahal, A.H.1
Feron-Rigodon, M.2
Madere, J.3
Subramanian, G.M.4
Bornstein, J.D.5
-
275
-
-
84883215493
-
The role of LOX and LOXL2 in scar formation after glaucoma surgery
-
PID: 23821193
-
Van Bergen T, Marshall D, Van de Veire S, et al. The role of LOX and LOXL2 in scar formation after glaucoma surgery. Invest Ophthalmol Vis Sci. 2013;54:5788–5796.
-
(2013)
Invest Ophthalmol Vis Sci
, vol.54
, pp. 5788-5796
-
-
Van Bergen, T.1
Marshall, D.2
Van de Veire, S.3
-
276
-
-
79955701910
-
Scraping fibrosis: expressway to the core of fibrosis
-
COI: 1:CAS:528:DC%2BC3MXls1Kgtb8%3D, PID: 21546973
-
Mehal WZ, Iredale J, Friedman SL. Scraping fibrosis: expressway to the core of fibrosis. Nat Med. 2011;17:552–553.
-
(2011)
Nat Med
, vol.17
, pp. 552-553
-
-
Mehal, W.Z.1
Iredale, J.2
Friedman, S.L.3
-
277
-
-
84977459436
-
Therapy of primary sclerosing cholangitis—today and tomorrow
-
PID: 26641242
-
Halilbasic E, Fuchs C, Hofer H, Paumgartner G, Trauner M. Therapy of primary sclerosing cholangitis—today and tomorrow. Dig Dis. 2015;33:149–163.
-
(2015)
Dig Dis
, vol.33
, pp. 149-163
-
-
Halilbasic, E.1
Fuchs, C.2
Hofer, H.3
Paumgartner, G.4
Trauner, M.5
-
278
-
-
1442301516
-
A pilot study of the safety and tolerability of etanercept in patients with alcoholic hepatitis
-
COI: 1:CAS:528:DC%2BD2cXitleisLs%3D, PID: 15046213
-
Menon KV, Stadheim L, Kamath PS, et al. A pilot study of the safety and tolerability of etanercept in patients with alcoholic hepatitis. Am J Gastroenterol. 2004;99:255–260.
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 255-260
-
-
Menon, K.V.1
Stadheim, L.2
Kamath, P.S.3
-
279
-
-
57249086241
-
A randomized, double-blinded, placebo-controlled multicenter trial of etanercept in the treatment of alcoholic hepatitis
-
COI: 1:CAS:528:DC%2BD1MXht1ertrw%3D, PID: 18848937
-
Boetticher NC, Peine CJ, Kwo P, et al. A randomized, double-blinded, placebo-controlled multicenter trial of etanercept in the treatment of alcoholic hepatitis. Gastroenterology. 2008;135:1953–1960.
-
(2008)
Gastroenterology
, vol.135
, pp. 1953-1960
-
-
Boetticher, N.C.1
Peine, C.J.2
Kwo, P.3
-
280
-
-
84874110062
-
Infliximab as a rescue treatment in difficult-to-treat autoimmune hepatitis
-
COI: 1:CAS:528:DC%2BC38XhvFWhtLvI, PID: 23178709
-
Weiler-Normann C, Schramm C, Quaas A, et al. Infliximab as a rescue treatment in difficult-to-treat autoimmune hepatitis. J Hepatol. 2013;58:529–534.
-
(2013)
J Hepatol
, vol.58
, pp. 529-534
-
-
Weiler-Normann, C.1
Schramm, C.2
Quaas, A.3
-
281
-
-
0034465251
-
Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial
-
COI: 1:CAS:528:DC%2BD3MXhtlKmsg%3D%3D, PID: 11113085
-
Akriviadis E, Botla R, Briggs W, et al. Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. Gastroenterology. 2000;119:1637–1648.
-
(2000)
Gastroenterology
, vol.119
, pp. 1637-1648
-
-
Akriviadis, E.1
Botla, R.2
Briggs, W.3
-
282
-
-
0033009509
-
Pentoxifylline inhibits TNF-alpha production from human alveolar macrophages
-
COI: 1:STN:280:DyaK1M7is1KksA%3D%3D, PID: 9927365
-
Marques LJ, Zheng L, Poulakis N, Guzman J, Costabel U. Pentoxifylline inhibits TNF-alpha production from human alveolar macrophages. Am J Respir Crit Care Med. 1999;159:508–511.
-
(1999)
Am J Respir Crit Care Med
, vol.159
, pp. 508-511
-
-
Marques, L.J.1
Zheng, L.2
Poulakis, N.3
Guzman, J.4
Costabel, U.5
-
283
-
-
45749153058
-
Insights into the regulation of TNF-alpha production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition
-
Deree J, Martins JO, Melbostad H, Loomis WH, Coimbra R. Insights into the regulation of TNF-alpha production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition. Clinics (Sao Paulo). 2008;63:321–328.
-
(2008)
Clinics (Sao Paulo)
, vol.63
, pp. 321-328
-
-
Deree, J.1
Martins, J.O.2
Melbostad, H.3
Loomis, W.H.4
Coimbra, R.5
-
284
-
-
77953552969
-
New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis
-
COI: 1:CAS:528:DC%2BC3cXntlajtro%3D, PID: 20447716
-
Wang Y, Gao J, Zhang D, et al. New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis. J Hepatol. 2010;53:132–144.
-
(2010)
J Hepatol
, vol.53
, pp. 132-144
-
-
Wang, Y.1
Gao, J.2
Zhang, D.3
-
285
-
-
84860390569
-
Inhibition of PDGF, TGF-beta, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib
-
COI: 1:CAS:528:DC%2BC3MXhtVGqurrM, PID: 21251937
-
Liu Y, Wang Z, Kwong SQ, et al. Inhibition of PDGF, TGF-beta, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib. J Hepatol. 2011;55:612–625.
-
(2011)
J Hepatol
, vol.55
, pp. 612-625
-
-
Liu, Y.1
Wang, Z.2
Kwong, S.Q.3
-
286
-
-
33644750470
-
Rimonabant: a selective blocker of the cannabinoid CB1 receptors for the management of obesity, smoking cessation and cardiometabolic risk factors
-
COI: 1:CAS:528:DC%2BD28XhvVKns7Y%3D, PID: 16503766
-
Gelfand EV, Cannon CP. Rimonabant: a selective blocker of the cannabinoid CB1 receptors for the management of obesity, smoking cessation and cardiometabolic risk factors. Expert Opin Investig Drugs. 2006;15:307–315.
-
(2006)
Expert Opin Investig Drugs
, vol.15
, pp. 307-315
-
-
Gelfand, E.V.1
Cannon, C.P.2
-
287
-
-
0036082703
-
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
-
COI: 1:CAS:528:DC%2BD38Xlt12gsLw%3D, PID: 12055599
-
Galli A, Crabb DW, Ceni E, et al. Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro. Gastroenterology. 2002;122:1924–1940.
-
(2002)
Gastroenterology
, vol.122
, pp. 1924-1940
-
-
Galli, A.1
Crabb, D.W.2
Ceni, E.3
-
288
-
-
84966340076
-
Effects of vitamin D supplementation on serum 25-hydroxyvitamin D concentrations in cirrhotic patients: a randomized controlled trial
-
PID: 27171112
-
Pilz S, Putz-Bankuti C, Gaksch M, et al. Effects of vitamin D supplementation on serum 25-hydroxyvitamin D concentrations in cirrhotic patients: a randomized controlled trial. Nutrients. 2016. doi:10.3390/nu8050278.
-
(2016)
Nutrients
-
-
Pilz, S.1
Putz-Bankuti, C.2
Gaksch, M.3
-
289
-
-
27644506926
-
TAK-652 inhibits CCR5-mediated human immunodeficiency virus type 1 infection in vitro and has favorable pharmacokinetics in humans
-
COI: 1:CAS:528:DC%2BD2MXht1Siu7zO, PID: 16251299
-
Baba M, Takashima K, Miyake H, et al. TAK-652 inhibits CCR5-mediated human immunodeficiency virus type 1 infection in vitro and has favorable pharmacokinetics in humans. Antimicrob Agents Chemother. 2005;49:4584–4591.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 4584-4591
-
-
Baba, M.1
Takashima, K.2
Miyake, H.3
-
290
-
-
84938271972
-
Improvements in APRI and FIB-4 fibrosis scores correlate with decreases in sCD14 in HIV-1 infected adults receiving cenicriviroc over 48 weeks (Abstract)
-
Thompson M, Chang W, Jenkins H, et al. Improvements in APRI and FIB-4 fibrosis scores correlate with decreases in sCD14 in HIV-1 infected adults receiving cenicriviroc over 48 weeks (Abstract). Hepatology. 2014;60:424A.
-
(2014)
Hepatology
, vol.60
, pp. 424A
-
-
Thompson, M.1
Chang, W.2
Jenkins, H.3
-
291
-
-
77950201652
-
Farglitazar lacks antifibrotic activity in patients with chronic hepatitis C infection
-
PID: 20004661
-
McHutchison J, Goodman Z, Patel K, et al. Farglitazar lacks antifibrotic activity in patients with chronic hepatitis C infection. Gastroenterology. 2010;138:1365–1373.
-
(2010)
Gastroenterology
, vol.138
, pp. 1365-1373
-
-
McHutchison, J.1
Goodman, Z.2
Patel, K.3
-
292
-
-
80055028155
-
Pentoxifylline improves nonalcoholic steatohepatitis: a randomized placebo-controlled trial
-
COI: 1:CAS:528:DC%2BC3MXhtlygsbrI, PID: 21748765
-
Zein CO, Yerian LM, Gogate P, et al. Pentoxifylline improves nonalcoholic steatohepatitis: a randomized placebo-controlled trial. Hepatology. 2011;54:1610–1619.
-
(2011)
Hepatology
, vol.54
, pp. 1610-1619
-
-
Zein, C.O.1
Yerian, L.M.2
Gogate, P.3
-
293
-
-
79959446947
-
Pentoxifylline for the treatment of non-alcoholic steatohepatitis: a randomized controlled trial
-
PID: 21677329
-
Van Wagner LB, Koppe SW, Brunt EM, et al. Pentoxifylline for the treatment of non-alcoholic steatohepatitis: a randomized controlled trial. Ann Hepatol. 2011;10:277–286.
-
(2011)
Ann Hepatol
, vol.10
, pp. 277-286
-
-
Van Wagner, L.B.1
Koppe, S.W.2
Brunt, E.M.3
-
294
-
-
84876732000
-
Liver injury from tumor necrosis factor-alpha antagonists: analysis of thirty-four cases
-
Ghabril M, Bonkovsky HL, Kum C, et al. Liver injury from tumor necrosis factor-alpha antagonists: analysis of thirty-four cases. Clin Gastroenterol Hepatol. 2013;11:558–564 e553.
-
Clin Gastroenterol Hepatol. 2013;11
, vol.558-564
, pp. e553
-
-
Ghabril, M.1
Bonkovsky, H.L.2
Kum, C.3
-
295
-
-
84884930937
-
The cardiovascular safety of diabetes drugs—insights from the rosiglitazone experience
-
COI: 1:CAS:528:DC%2BC3sXhsF2ksb7E, PID: 23992603
-
Hiatt WR, Kaul S, Smith RJ. The cardiovascular safety of diabetes drugs—insights from the rosiglitazone experience. N Engl J Med. 2013;369:1285–1287.
-
(2013)
N Engl J Med
, vol.369
, pp. 1285-1287
-
-
Hiatt, W.R.1
Kaul, S.2
Smith, R.J.3
-
296
-
-
84925308328
-
Risk of drug-induced liver injury from tumor necrosis factor antagonists
-
COI: 1:CAS:528:DC%2BC2cXhsFalsbfE, PID: 25131534
-
Bjornsson ES, Gunnarsson BI, Grondal G, et al. Risk of drug-induced liver injury from tumor necrosis factor antagonists. Clin Gastroenterol Hepatol. 2015;13:602–608.
-
(2015)
Clin Gastroenterol Hepatol
, vol.13
, pp. 602-608
-
-
Bjornsson, E.S.1
Gunnarsson, B.I.2
Grondal, G.3
-
297
-
-
0023812878
-
Features reflective of early prognosis in corticosteroid-treated severe autoimmune chronic active hepatitis
-
COI: 1:STN:280:DyaL1c3ntFyktw%3D%3D, PID: 3391372
-
Czaja AJ, Rakela J, Ludwig J. Features reflective of early prognosis in corticosteroid-treated severe autoimmune chronic active hepatitis. Gastroenterology. 1988;95:448–453.
-
(1988)
Gastroenterology
, vol.95
, pp. 448-453
-
-
Czaja, A.J.1
Rakela, J.2
Ludwig, J.3
-
298
-
-
79952203791
-
Early predictors of corticosteroid treatment failure in icteric presentations of autoimmune hepatitis
-
PID: 21374663
-
Yeoman AD, Westbrook RH, Zen Y, et al. Early predictors of corticosteroid treatment failure in icteric presentations of autoimmune hepatitis. Hepatology. 2011;53:926–934.
-
(2011)
Hepatology
, vol.53
, pp. 926-934
-
-
Yeoman, A.D.1
Westbrook, R.H.2
Zen, Y.3
-
299
-
-
84866393237
-
Systematic review: managing suboptimal treatment responses in autoimmune hepatitis with conventional and nonstandard drugs
-
COI: 1:CAS:528:DC%2BC38XhvVelu7zM, PID: 22973822
-
Selvarajah V, Montano-Loza AJ, Czaja AJ. Systematic review: managing suboptimal treatment responses in autoimmune hepatitis with conventional and nonstandard drugs. Aliment Pharmacol Ther. 2012;36:691–707.
-
(2012)
Aliment Pharmacol Ther
, vol.36
, pp. 691-707
-
-
Selvarajah, V.1
Montano-Loza, A.J.2
Czaja, A.J.3
-
300
-
-
84960495501
-
Diagnosis and management of autoimmune hepatitis: current status and future directions
-
PID: 26934884
-
Czaja AJ. Diagnosis and management of autoimmune hepatitis: current status and future directions. Gut Liver. 2016;10:177–203.
-
(2016)
Gut Liver
, vol.10
, pp. 177-203
-
-
Czaja, A.J.1
-
301
-
-
84861619812
-
MicroRNAs in liver disease
-
COI: 1:CAS:528:DC%2BC38XnslSnsrc%3D, PID: 22504185
-
Wang XW, Heegaard NH, Orum H. MicroRNAs in liver disease. Gastroenterology. 2012;142:1431–1443.
-
(2012)
Gastroenterology
, vol.142
, pp. 1431-1443
-
-
Wang, X.W.1
Heegaard, N.H.2
Orum, H.3
-
302
-
-
79953763871
-
Systematic review on the treatment of pentoxifylline in patients with nonalcoholic fatty liver disease
-
COI: 1:CAS:528:DC%2BC3MXltVWqsbk%3D, PID: 21477300
-
Li W, Zheng L, Sheng C, et al. Systematic review on the treatment of pentoxifylline in patients with nonalcoholic fatty liver disease. Lipids Health Dis. 2011;10:49.
-
(2011)
Lipids Health Dis
, vol.10
, pp. 49
-
-
Li, W.1
Zheng, L.2
Sheng, C.3
|