The effects of angiotensin blocking agents on the progression of liver fibrosis in the HALT-C Trial cohort

Digestive Diseases and Sciences

Volumn 56, Issue 2, 2011, Pages 564-568

  Abu Dayyeh, Barham K ^a   Yang, May ^b   Dienstag, Jules L ^a   Chung, Raymond T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NEW ENGLAND RESEARCH INSTITUTES   (United States)

Author keywords

ACE inhibitors; Angiotensin receptor blockers; Diabetes; Hypertension; Liver fibrosis; Renin angiotensin system

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; FEMALE; HEPATITIS C; HUMAN; LIVER BIOPSY; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCORING SYSTEM;

ADULT; ANGIOTENSIN RECEPTOR ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; FEMALE; HEPATITIS C, CHRONIC; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED;

EID: 79952453566     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-010-1507-8     Document Type: Article

References (22)

1. R Bataller P Gines JM Nicolas MN Gorbig E Garcia-Ramallo X Gasull 2000 Angiotensin II induces contraction and proliferation of human hepatic stellate cells Gastroenterology 118 1149 1156 1:CAS:528:DC%2BD3cXktlaiu7w%3D 10.1016/S0016-5085(00)70368-4 10833490 (Pubitemid 30346992)
2. R Bataller E Gabele R Schoonhoven T Morris M Lehnert L Yang 2003 Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liver Am J Physiol Gastrointest Liver Physiol 285 G642 G651 1:CAS:528:DC%2BD3sXnsVGmu7w%3D 12773299
3. R Bataller RF Schwabe YH Choi L Yang YH Paik J Lindquist 2003 Nadph oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis J Clin Invest 112 1383 1394 1:CAS:528: DC%2BD3sXovVGqs7s%3D 14597764 (Pubitemid 38057692)
4. R Bataller P Sancho-Bru P Gines JM Lora A Al-Garawi M Sole 2003 Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II Gastroenterology 125 117 125 1:CAS:528: DC%2BD3sXmtVWqur4%3D 10.1016/S0016-5085(03)00695-4 12851877 (Pubitemid 36799113)
5. S Yokohama Y Tokusashi K Nakamura Y Tamaki S Okamoto M Okada 2006 Inhibitory effect of angiotensin II receptor antagonist on hepatic stellate cell activation in non-alcoholic steatohepatitis World J Gastroenterol 12 322 326 1:CAS:528:DC%2BD28Xis1yitrY%3D 16482638 (Pubitemid 43336936)
6. HS Wei DG Li HM Lu YT Zhan ZR Wang X Huang 2000 Effects of AT1 receptor antagonist, losartan, on rat hepatic fibrosis induced by CCL(4) World J Gastroenterol 6 540 545 1:CAS:528:DC%2BD3cXmsVSqs7k%3D 11819643 (Pubitemid 30665265)
7. H Yoshiji S Kuriyama J Yoshii Y Ikenaka R Noguchi T Nakatani 2001 Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats Hepatology 34 745 750 1:CAS:528: DC%2BD3MXns1Kisrs%3D 10.1053/jhep.2001.28231 11584371 (Pubitemid 32927999)
8. JR Jonsson AD Clouston Y Ando LI Kelemen MJ Horn MD Adamson 2001 Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis Gastroenterology 121 148 155 1:CAS:528:DC%2BD3MXlt1yktL4%3D 10.1053/gast.2001.25480 11438504 (Pubitemid 32591525)
9. V Croquet F Moal N Veal J Wang F Oberti J Roux 2002 Hemodynamic and antifibrotic effects of losartan in rats with liver fibrosis and/or portal hypertension J Hepatol 37 773 780 1:CAS:528:DC%2BD38XoslCjtb4%3D 10.1016/S0168-8278(02)00307-0 12445418 (Pubitemid 35404216)
10. K Kanno S Tazuma K Chayama 2003 AT1A-deficient mice show less severe progression of liver fibrosis induced by CCL(4) Biochem Biophys Res Commun 308 177 183 1:CAS:528:DC%2BD3sXlvVCkurw%3D 10.1016/S0006-291X(03)01357-3 12890498 (Pubitemid 36904138)
11. YH Wei L Jun L Jun 2004 Effect of losartan, an angiotensin II antagonist, on hepatic fibrosis induced by CCL4 in rats Dig Dis Sci 49 1589 1594 1:CAS:528:DC%2BD2cXnvFGrtrw%3D 10.1023/B:DDAS.0000043369.88701.5b 15573910 (Pubitemid 39335540)
12. L Yang R Bataller J Dulyx TM Coffman P Gines RA Rippe 2005 Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice J Hepatol 43 317 323 1:CAS:528:DC%2BD2MXlvFalsL0%3D 10.1016/j.jhep.2005.02.034 15964094 (Pubitemid 40956886)
13. Y Terui T Saito H Watanabe H Togashi S Kawata Y Kamada 2002 Effect of angiotensin receptor antagonist on liver fibrosis in early stages of chronic hepatitis C Hepatology 36 1022 10.1053/jhep.2002.32679 12297856
14. W Debernardi-Venon S Martini F Biasi B Vizio A Termine G Poli 2007 AT1 receptor antagonist candesartan in selected cirrhotic patients: Effect on portal pressure and liver fibrosis markers J Hepatol 46 1026 1033 1:CAS:528: DC%2BD2sXkvFGjsLc%3D 10.1016/j.jhep.2007.01.017 17336417 (Pubitemid 46669730)
15. S Yokohama M Yoneda M Haneda S Okamoto M Okada K Aso 2004 Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis Hepatology 40 1222 1225 1:CAS:528:DC%2BD2cXhtVCgt7jK 10.1002/hep.20420 15382153 (Pubitemid 39425579)
16. A Rimola MC Londono G Guevara M Bruguera M Navasa X Forns 2004 Beneficial effect of angiotensin-blocking agents on graft fibrosis in hepatitis C recurrence after liver transplantation Transplantation 78 686 691 1:CAS:528:DC%2BD2cXnsFGqsrY%3D 10.1097/01.TP.0000128913.09774.CE 15371669 (Pubitemid 39244729)
17. H Yoshiji R Noguchi H Fukui 2005 Combined effect of an ace inhibitor, perindopril, and interferon on liver fibrosis markers in patients with chronic hepatitis C J Gastroenterol 40 215 216 10.1007/s00535-004-1523-6 15770410 (Pubitemid 40425214)
18. KE Corey N Shah J Misdraji BK Abu Dayyeh H Zheng AK Bhan 2009 The effect of angiotensin-blocking agents on liver fibrosis in patients with hepatitis C Liver Int 29 748 753 1:CAS:528:DC%2BD1MXlvFSjurw%3D 10.1111/j.1478-3231.2009. 01973.x 19220742
19. AM Di Bisceglie ML Shiffman GT Everson KL Lindsay JE Everhart EC Wright 2008 Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon N Engl J Med 359 2429 2441 1:CAS:528:DC%2BD1cXhsVGns7jN 10.1056/NEJMoa0707615 19052125
20. K Ishak A Baptista L Bianchi F Callea J De Groote F Gudat 1995 Histological grading and staging of chronic hepatitis J Hepatol 22 696 699 1:STN:280:DyaK28%2FjsFWntw%3D%3D 10.1016/0168-8278(95)80226-6 7560864
21. JE Everhart EC Wright ZD Goodman JL Dienstag JC Hoefs DE Kleiner 2010 Prognostic value of Ishak fibrosis stage: Findings from the hepatitis C antiviral long-term treatment against cirrhosis trial Hepatology 51 585 594 10.1002/hep.23659 20101752
22. E Cholongitas S Vibhakorn F Lodato AK Burroughs 2010 Angiotensin II antagonists in patients with recurrent hepatitis C virus infection after liver transplantation Liver Int 30 334 335 10.1111/j.1478-3231.2009.02059.x 19515217