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Volumn 33, Issue 3, 2013, Pages 338-352

Vitamin D in chronic liver disease

Author keywords

25 hydroxyvitamin D; Bioavailability; Cholecalciferol; Epimers; Hepatic disease; Hepatic osteodystrophy; Vitamin D metabolites

Indexed keywords

25 HYDROXYVITAMIN D; CALCIUM; COLECALCIFEROL; ERGOCALCIFEROL; PEGINTERFERON; RIBAVIRIN; VITAMIN D;

EID: 84873731007     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12106     Document Type: Review
Times cited : (142)

References (87)
  • 2
    • 0041322965 scopus 로고    scopus 로고
    • AGA technical review on osteoporosis in hepatic disorders
    • Leslie W. AGA technical review on osteoporosis in hepatic disorders. Gastroenterology 2003; 125: 941-66.
    • (2003) Gastroenterology , vol.125 , pp. 941-966
    • Leslie, W.1
  • 3
    • 77956189184 scopus 로고    scopus 로고
    • Prevalence of vitamin D deficiency in chronic liver disease
    • Arteh J, Narra S, Nair S. Prevalence of vitamin D deficiency in chronic liver disease. Dig Dis Sci 2010; 55: 2624-8.
    • (2010) Dig Dis Sci , vol.55 , pp. 2624-2628
    • Arteh, J.1    Narra, S.2    Nair, S.3
  • 4
    • 18544394411 scopus 로고    scopus 로고
    • Guidelines on the management of osteoporosis associated with chronic liver disease
    • Collier JD, Ninkovic M, Compston JE. Guidelines on the management of osteoporosis associated with chronic liver disease. Gut 2002; 50(Suppl 1): i1-9.
    • (2002) Gut , vol.50 , Issue.SUPPL 1
    • Collier, J.D.1    Ninkovic, M.2    Compston, J.E.3
  • 5
    • 67649205149 scopus 로고    scopus 로고
    • EASL Clinical practice guidelines: Management of cholestatic liver diseases
    • EASL.
    • EASL. EASL Clinical practice guidelines: Management of cholestatic liver diseases. J Hepatol 2009; 51: 237-67.
    • (2009) J Hepatol , vol.51 , pp. 237-267
  • 6
    • 65549145901 scopus 로고    scopus 로고
    • Nuclear receptors as therapeutic targets in cholestatic liver diseases
    • Zollner G, Trauner M. Nuclear receptors as therapeutic targets in cholestatic liver diseases. Br J Pharmacol 2009; 156: 7-27.
    • (2009) Br J Pharmacol , vol.156 , pp. 7-27
    • Zollner, G.1    Trauner, M.2
  • 7
    • 78649697894 scopus 로고    scopus 로고
    • Vitamin D, disease and therapeutic opportunities
    • Plum LA, Deluca HF. Vitamin D, disease and therapeutic opportunities. Nat Rev Drug Discov 2010; 9: 941-55.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 941-955
    • Plum, L.A.1    Deluca, H.F.2
  • 8
    • 79953662213 scopus 로고    scopus 로고
    • The functional metabolism and molecular biology of vitamin D action
    • Plum L, Deluca H. The functional metabolism and molecular biology of vitamin D action. Clin Rev Bone Miner Metab 2009; 7: 20-41.
    • (2009) Clin Rev Bone Miner Metab , vol.7 , pp. 20-41
    • Plum, L.1    Deluca, H.2
  • 9
    • 77954846408 scopus 로고    scopus 로고
    • Novel biomarkers predict liver fibrosis in hepatitis C patients: alpha 2 macroglobulin, vitamin D binding protein and apolipoprotein AI
    • Ho A-S, Cheng C-C, Lee S-C, et al. Novel biomarkers predict liver fibrosis in hepatitis C patients: alpha 2 macroglobulin, vitamin D binding protein and apolipoprotein AI. J Biomed Sci 2010; 17: 58.
    • (2010) J Biomed Sci , vol.17 , pp. 58
    • Ho, A.-S.1    Cheng, C.-C.2    Lee, S.-C.3
  • 11
    • 4344665018 scopus 로고    scopus 로고
    • Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression
    • Wang TT, Nestel FP, Bourdeau V, et al. Cutting edge: 1, 25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J Immunol 2004; 173: 2909-12.
    • (2004) J Immunol , vol.173 , pp. 2909-2912
    • Wang, T.T.1    Nestel, F.P.2    Bourdeau, V.3
  • 13
    • 0345743611 scopus 로고    scopus 로고
    • The pleiotropic actions of vitamin D
    • Lin R, White JH. The pleiotropic actions of vitamin D. BioEssays 2004; 26: 21-8.
    • (2004) BioEssays , vol.26 , pp. 21-28
    • Lin, R.1    White, J.H.2
  • 14
    • 84858150326 scopus 로고    scopus 로고
    • Vitamin D metabolism and signaling in the immune system
    • White JH. Vitamin D metabolism and signaling in the immune system. Rev Endocr Metab Disord 2012; 13: 21-9.
    • (2012) Rev Endocr Metab Disord , vol.13 , pp. 21-29
    • White, J.H.1
  • 15
    • 58149385796 scopus 로고    scopus 로고
    • Nonclassic actions of vitamin D
    • Bikle D. Nonclassic actions of vitamin D. J Clin Endocrinol Metab 2009; 94: 26-34.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 26-34
    • Bikle, D.1
  • 16
    • 77950480477 scopus 로고    scopus 로고
    • Vitamin D and the magic mountain: The anti-infectious role of the vitamin
    • Chesney RW. Vitamin D and the magic mountain: The anti-infectious role of the vitamin. J Pediatr 2010; 156: 698-703.
    • (2010) J Pediatr , vol.156 , pp. 698-703
    • Chesney, R.W.1
  • 17
    • 3242762258 scopus 로고    scopus 로고
    • Candidate reference method for the quantification of circulating 25-hydroxyvitamin D3 by liquid chromatography-tandem mass spectrometry
    • Vogeser M, Kyriatsoulis A, Huber E, Kobold U. Candidate reference method for the quantification of circulating 25-hydroxyvitamin D3 by liquid chromatography-tandem mass spectrometry. Clin Chem 2004; 50: 1415-7.
    • (2004) Clin Chem , vol.50 , pp. 1415-1417
    • Vogeser, M.1    Kyriatsoulis, A.2    Huber, E.3    Kobold, U.4
  • 18
    • 77957885962 scopus 로고    scopus 로고
    • Quantitative determination of vitamin D metabolites in plasma using UHPLC-MS/MS
    • Ding S, Schoenmakers I, Jones K, et al. Quantitative determination of vitamin D metabolites in plasma using UHPLC-MS/MS. Anal Bioanal Chem 2010; 398: 779-89.
    • (2010) Anal Bioanal Chem , vol.398 , pp. 779-789
    • Ding, S.1    Schoenmakers, I.2    Jones, K.3
  • 19
    • 0035342672 scopus 로고    scopus 로고
    • Differential activities of 1alpha,25-dihydroxy-16-ene-vitamin D(3) analogs and their 3-epimers on human promyelocytic leukemia (HL-60) cell differentiation and apoptosis
    • Nakagawa K, Sowa Y, Kurobe M, et al. Differential activities of 1alpha, 25-dihydroxy-16-ene-vitamin D(3) analogs and their 3-epimers on human promyelocytic leukemia (HL-60) cell differentiation and apoptosis. Steroids 2001; 66: 327-37.
    • (2001) Steroids , vol.66 , pp. 327-337
    • Nakagawa, K.1    Sowa, Y.2    Kurobe, M.3
  • 20
    • 11144357719 scopus 로고    scopus 로고
    • C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation
    • Kamao M, Tatematsu S, Hatakeyama S, et al. C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation. J Biol Chem 2004; 279: 15897-907.
    • (2004) J Biol Chem , vol.279 , pp. 15897-15907
    • Kamao, M.1    Tatematsu, S.2    Hatakeyama, S.3
  • 21
    • 78650887156 scopus 로고    scopus 로고
    • Accuracy of 25-hydroxyvitamin D assays: Confronting the issues
    • Carter GD. Accuracy of 25-hydroxyvitamin D assays: Confronting the issues. Curr Drug Targets 2011; 12: 19-28.
    • (2011) Curr Drug Targets , vol.12 , pp. 19-28
    • Carter, G.D.1
  • 22
    • 84861331797 scopus 로고    scopus 로고
    • Variability in the analysis of 25-hydroxyvitamin D by liquid chromatography-tandem mass spectrometry: The devil is in the detail
    • Couchman L, Benton CM, Moniz CF. Variability in the analysis of 25-hydroxyvitamin D by liquid chromatography-tandem mass spectrometry: The devil is in the detail. Clin Chim Acta 2012; 413: 1239-43.
    • (2012) Clin Chim Acta , vol.413 , pp. 1239-1243
    • Couchman, L.1    Benton, C.M.2    Moniz, C.F.3
  • 23
    • 33747637729 scopus 로고    scopus 로고
    • C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status
    • Singh RJ. C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status. J Clin Endocrin Metab 2006; 91: 3055-61.
    • (2006) J Clin Endocrin Metab , vol.91 , pp. 3055-3061
    • Singh, R.J.1
  • 24
    • 79959214925 scopus 로고    scopus 로고
    • Misleading measures in Vitamin D analysis: A novel LC-MS/MS assay to account for epimers and isobars
    • Shah I, James R, Barker J, Petroczi A, Naughton DP. Misleading measures in Vitamin D analysis: A novel LC-MS/MS assay to account for epimers and isobars. Nutr J 2011; 10: 46.
    • (2011) Nutr J , vol.10 , pp. 46
    • Shah, I.1    James, R.2    Barker, J.3    Petroczi, A.4    Naughton, D.P.5
  • 26
    • 0015401959 scopus 로고
    • The distribution and storage of vitamin D and its metabolites in human tissues
    • Mawer EB, Backhouse J, Holman CA, Lumb GA, Stanbury SW. The distribution and storage of vitamin D and its metabolites in human tissues. Clin Sci 1972; 43: 413-31.
    • (1972) Clin Sci , vol.43 , pp. 413-431
    • Mawer, E.B.1    Backhouse, J.2    Holman, C.A.3    Lumb, G.A.4    Stanbury, S.W.5
  • 28
    • 85047676979 scopus 로고    scopus 로고
    • 24,25-Dihydroxyvitamin D-active metabolite or inactive catabolite?
    • St-Arnaud R, Glorieux FH. 24, 25-Dihydroxyvitamin D-active metabolite or inactive catabolite? Endocrinology 1998; 139: 3371-4.
    • (1998) Endocrinology , vol.139 , pp. 3371-3374
    • St-Arnaud, R.1    Glorieux, F.H.2
  • 30
    • 79960104336 scopus 로고    scopus 로고
    • Evaluation, treatment, and prevention of vitamin D deficiency: An endocrine society clinical practice guideline
    • Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: An endocrine society clinical practice guideline. J Clinical Endocrin Metab 2011; 96: 1911-30.
    • (2011) J Clinical Endocrin Metab , vol.96 , pp. 1911-1930
    • Holick, M.F.1    Binkley, N.C.2    Bischoff-Ferrari, H.A.3
  • 31
    • 79551504112 scopus 로고    scopus 로고
    • Meta-analysis of observational studies of serum 25-hydroxyvitamin D levels and colorectal, breast and prostate cancer and colorectal adenoma
    • Gandini S, Boniol M, Haukka J, et al. Meta-analysis of observational studies of serum 25-hydroxyvitamin D levels and colorectal, breast and prostate cancer and colorectal adenoma. Int J Cancer 2011; 128: 1414-24.
    • (2011) Int J Cancer , vol.128 , pp. 1414-1424
    • Gandini, S.1    Boniol, M.2    Haukka, J.3
  • 32
    • 34347266963 scopus 로고    scopus 로고
    • The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis
    • Pittas AG, Lau J, Hu FB, Dawson-Hughes B. The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. J Clin Endocrinol Metab 2007; 92: 2017-29.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 2017-2029
    • Pittas, A.G.1    Lau, J.2    Hu, F.B.3    Dawson-Hughes, B.4
  • 33
    • 27744533661 scopus 로고    scopus 로고
    • Relationship between serum parathyroid hormone levels, vitamin D sufficiency, and calcium intake
    • Steingrimsdottir L, Gunnarsson O, Indridason OS, Franzson L, Sigurdsson G. Relationship between serum parathyroid hormone levels, vitamin D sufficiency, and calcium intake. JAMA 2005; 294: 2336-41.
    • (2005) JAMA , vol.294 , pp. 2336-2341
    • Steingrimsdottir, L.1    Gunnarsson, O.2    Indridason, O.S.3    Franzson, L.4    Sigurdsson, G.5
  • 34
    • 0030817895 scopus 로고    scopus 로고
    • Prevalence of vitamin D insufficiency in an adult normal population
    • Chapuy MC, Preziosi P, Maamer M, et al. Prevalence of vitamin D insufficiency in an adult normal population. Osteoporos Int 1997; 7: 439-43.
    • (1997) Osteoporos Int , vol.7 , pp. 439-443
    • Chapuy, M.C.1    Preziosi, P.2    Maamer, M.3
  • 36
    • 78650918917 scopus 로고    scopus 로고
    • Institute of Medicine. Washington, DC: National Academies Press
    • Institute of Medicine. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: National Academies Press, 2011.
    • (2011) Dietary Reference Intakes for Calcium and Vitamin D
  • 37
    • 34147144615 scopus 로고    scopus 로고
    • Vitamin D and parathyroid hormone in outpatients with noncholestatic chronic liver disease
    • Fisher L, Fisher A. Vitamin D and parathyroid hormone in outpatients with noncholestatic chronic liver disease. Clin Gastroenterol Hepatol 2007; 5: 513-20.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 513-520
    • Fisher, L.1    Fisher, A.2
  • 38
    • 0030012271 scopus 로고    scopus 로고
    • Metabolic bone disease of liver cirrhosis: Is it parallel to the clinical severity of cirrhosis?
    • Chen CC, Wang SS, Jeng FS, Lee SD. Metabolic bone disease of liver cirrhosis: Is it parallel to the clinical severity of cirrhosis? J Gastroenterol Hepatol 1996; 11: 417-21.
    • (1996) J Gastroenterol Hepatol , vol.11 , pp. 417-421
    • Chen, C.C.1    Wang, S.S.2    Jeng, F.S.3    Lee, S.D.4
  • 39
    • 0031034507 scopus 로고    scopus 로고
    • Osteoporosis and bone mineral metabolism disorders in cirrhotic patients referred for orthotopic liver transplantation
    • Monegal A, Navasa M, Guanabens N, et al. Osteoporosis and bone mineral metabolism disorders in cirrhotic patients referred for orthotopic liver transplantation. Calcif Tissue Int 1997; 60: 148-54.
    • (1997) Calcif Tissue Int , vol.60 , pp. 148-154
    • Monegal, A.1    Navasa, M.2    Guanabens, N.3
  • 40
    • 84857362329 scopus 로고    scopus 로고
    • Review article: The extra-skeletal effects of vitamin D in chronic hepatitis C infection
    • Cholongitas E, Theocharidou E, Goulis J, et al. Review article: The extra-skeletal effects of vitamin D in chronic hepatitis C infection. Aliment Pharmacol Ther 2012; 35: 634-46.
    • (2012) Aliment Pharmacol Ther , vol.35 , pp. 634-646
    • Cholongitas, E.1    Theocharidou, E.2    Goulis, J.3
  • 41
    • 77958107912 scopus 로고    scopus 로고
    • Disturbances of parathyroid hormone-vitamin D axis in non-cholestatic chronic liver disease: a cross-sectional study
    • Miroliaee A, Nasiri-Toosi M, Khalilzadeh O, et al. Disturbances of parathyroid hormone-vitamin D axis in non-cholestatic chronic liver disease: a cross-sectional study. Hepatol Int 2010; 4: 634-40.
    • (2010) Hepatol Int , vol.4 , pp. 634-640
    • Miroliaee, A.1    Nasiri-Toosi, M.2    Khalilzadeh, O.3
  • 42
    • 78649450740 scopus 로고    scopus 로고
    • Oral vitamin D replacement is effective in chronic liver disease
    • Rode A, Fourlanos S, Nicoll A. Oral vitamin D replacement is effective in chronic liver disease. Gastroenterol Clin Biol 2010; 34: 618-20.
    • (2010) Gastroenterol Clin Biol , vol.34 , pp. 618-620
    • Rode, A.1    Fourlanos, S.2    Nicoll, A.3
  • 43
    • 84859461279 scopus 로고    scopus 로고
    • Association of 25-hydroxyvitamin D levels with liver dysfunction and mortality in chronic liver disease
    • Putz-Bankuti C, Pilz S, Stojakovic T, et al. Association of 25-hydroxyvitamin D levels with liver dysfunction and mortality in chronic liver disease. Liver Int 2012; 32: 845-51.
    • (2012) Liver Int , vol.32 , pp. 845-851
    • Putz-Bankuti, C.1    Pilz, S.2    Stojakovic, T.3
  • 44
    • 14844311841 scopus 로고    scopus 로고
    • The heterogeneity of bone disease in cirrhosis: A multi-variate analysis
    • Crawford BAL, Kam C, Donaghy AJ, Mccaughan GW. The heterogeneity of bone disease in cirrhosis: A multi-variate analysis. Osteoporos Int 2003; 14: 987-94.
    • (2003) Osteoporos Int , vol.14 , pp. 987-994
    • Crawford, B.A.L.1    Kam, C.2    Donaghy, A.J.3    Mccaughan, G.W.4
  • 45
    • 34547485376 scopus 로고    scopus 로고
    • Associations between serum 25-hydroxyvitamin D3 concentrations and liver histology in patients with non-alcoholic fatty liver disease
    • Targher G, Bertolini L, Scala L, et al. Associations between serum 25-hydroxyvitamin D3 concentrations and liver histology in patients with non-alcoholic fatty liver disease. Nutr Metab Cardiovasc Dis 2007; 17: 517-24.
    • (2007) Nutr Metab Cardiovasc Dis , vol.17 , pp. 517-524
    • Targher, G.1    Bertolini, L.2    Scala, L.3
  • 46
    • 79960152007 scopus 로고    scopus 로고
    • Strong association between non alcoholic fatty liver disease (NAFLD) and low 25(OH) vitamin D levels in an adult population with normal serum liver enzymes
    • Barchetta I, Angelico F, Ben M, et al. Strong association between non alcoholic fatty liver disease (NAFLD) and low 25(OH) vitamin D levels in an adult population with normal serum liver enzymes. BMC Medicine 2011; 9: 85.
    • (2011) BMC Medicine , vol.9 , pp. 85
    • Barchetta, I.1    Angelico, F.2    Ben, M.3
  • 47
    • 0033834502 scopus 로고    scopus 로고
    • Bone density and metabolism in patients with viral hepatitis and cholestatic liver diseases before and after liver transplantation
    • Trautwein C, Possienke M, Schlitt HJ, et al. Bone density and metabolism in patients with viral hepatitis and cholestatic liver diseases before and after liver transplantation. Am J Gastroenterol 2000; 95: 2343-51.
    • (2000) Am J Gastroenterol , vol.95 , pp. 2343-2351
    • Trautwein, C.1    Possienke, M.2    Schlitt, H.J.3
  • 48
    • 77950598712 scopus 로고    scopus 로고
    • Vitamin D and the risk of acute allograft rejection following human liver transplantation
    • Bitetto D, Fabris C, Falleti E, et al. Vitamin D and the risk of acute allograft rejection following human liver transplantation. Liver Int 2010; 30: 417-44.
    • (2010) Liver Int , vol.30 , pp. 417-444
    • Bitetto, D.1    Fabris, C.2    Falleti, E.3
  • 49
    • 84857129618 scopus 로고    scopus 로고
    • Serum vitamin D levels are not predictive of the progression of chronic liver disease in hepatitis C patients with advanced fibrosis
    • Corey KE, Zheng H, Mendez-Navarro J, et al. Serum vitamin D levels are not predictive of the progression of chronic liver disease in hepatitis C patients with advanced fibrosis. PLoS ONE 2012; 7: e27144.
    • (2012) PLoS ONE , vol.7
    • Corey, K.E.1    Zheng, H.2    Mendez-Navarro, J.3
  • 50
    • 0022461489 scopus 로고
    • Free 25-hydroxyvitamin D levels are normal in subjects with liver disease and reduced total 25-hydroxyvitamin D levels
    • Bikle DD, Halloran BP, Gee E, Ryzen E, Haddad JG. Free 25-hydroxyvitamin D levels are normal in subjects with liver disease and reduced total 25-hydroxyvitamin D levels. J Clin Invest 1986; 78: 748-52.
    • (1986) J Clin Invest , vol.78 , pp. 748-752
    • Bikle, D.D.1    Halloran, B.P.2    Gee, E.3    Ryzen, E.4    Haddad, J.G.5
  • 51
    • 0032918417 scopus 로고    scopus 로고
    • Osteopathy and resistance to vitamin D toxicity in mice null for vitamin D binding protein
    • Safadi FF, Thornton P, Magiera H, et al. Osteopathy and resistance to vitamin D toxicity in mice null for vitamin D binding protein. J Clin Invest 1999; 103: 239-51.
    • (1999) J Clin Invest , vol.103 , pp. 239-251
    • Safadi, F.F.1    Thornton, P.2    Magiera, H.3
  • 52
    • 46349085557 scopus 로고    scopus 로고
    • Vitamin D-binding protein influences total circulating levels of 1,25-dihydroxyvitamin D3 but does not directly modulate the bioactive levels of the hormone in vivo
    • Zella LA, Shevde NK, Hollis BW, Cooke NE, Pike JW. Vitamin D-binding protein influences total circulating levels of 1, 25-dihydroxyvitamin D3 but does not directly modulate the bioactive levels of the hormone in vivo. Endocrinology 2008; 149: 3656-67.
    • (2008) Endocrinology , vol.149 , pp. 3656-3667
    • Zella, L.A.1    Shevde, N.K.2    Hollis, B.W.3    Cooke, N.E.4    Pike, J.W.5
  • 53
    • 0022372863 scopus 로고
    • Metabolism of vitamin D in patients with primary biliary cirrhosis and alcoholic liver disease
    • Mawer EB, Klass HJ, Warnes TW, Berry JL. Metabolism of vitamin D in patients with primary biliary cirrhosis and alcoholic liver disease. Clin Sci(Lond) 1985; 69: 561-70.
    • (1985) Clin Sci(Lond) , vol.69 , pp. 561-570
    • Mawer, E.B.1    Klass, H.J.2    Warnes, T.W.3    Berry, J.L.4
  • 54
    • 0022544074 scopus 로고
    • Hepatic osteodystrophy: Vitamin D metabolism in patients with liver disease
    • Compston JE. Hepatic osteodystrophy: Vitamin D metabolism in patients with liver disease. Gut 1986; 27: 1073-90.
    • (1986) Gut , vol.27 , pp. 1073-1090
    • Compston, J.E.1
  • 55
    • 0023613052 scopus 로고
    • Main endocrine modulators of vitamin D hydroxylases in human pathophysiology
    • Caniggia A, Lore F, di Cairano G, Nuti R. Main endocrine modulators of vitamin D hydroxylases in human pathophysiology. J Steroid Biochem 1987; 27: 815-24.
    • (1987) J Steroid Biochem , vol.27 , pp. 815-824
    • Caniggia, A.1    Lore, F.2    di Cairano, G.3    Nuti, R.4
  • 56
    • 77955052903 scopus 로고    scopus 로고
    • Common genetic determinants of vitamin D insufficiency: A genome-wide association study
    • Wang TJ, Zhang F, Richards JB, et al. Common genetic determinants of vitamin D insufficiency: A genome-wide association study. Lancet 2010; 376: 180-8.
    • (2010) Lancet , vol.376 , pp. 180-188
    • Wang, T.J.1    Zhang, F.2    Richards, J.B.3
  • 57
    • 84868198010 scopus 로고    scopus 로고
    • Common genetic variation in vitamin D metabolism is associated with liver stiffness
    • Grünhage F, Hochrath K, Krawczyk M, et al. Common genetic variation in vitamin D metabolism is associated with liver stiffness. Hepatology 2012; 56: 1883-91.
    • (2012) Hepatology , vol.56 , pp. 1883-1891
    • Grünhage, F.1    Hochrath, K.2    Krawczyk, M.3
  • 58
    • 84858281844 scopus 로고    scopus 로고
    • Combined effect of 25-OH vitamin D plasma levels and genetic vitamin D receptor (NR 1I1) variants on fibrosis progression rate in HCV patients
    • Baur K, Mertens JC, Schmitt J, et al. Combined effect of 25-OH vitamin D plasma levels and genetic vitamin D receptor (NR 1I1) variants on fibrosis progression rate in HCV patients. Liver Int 2012; 32: 635-43.
    • (2012) Liver Int , vol.32 , pp. 635-643
    • Baur, K.1    Mertens, J.C.2    Schmitt, J.3
  • 59
    • 0036139687 scopus 로고    scopus 로고
    • Genetic association of vitamin D receptor polymorphisms with primary biliary cirrhosis and autoimmune hepatitis
    • Vogel A. Genetic association of vitamin D receptor polymorphisms with primary biliary cirrhosis and autoimmune hepatitis. Hepatology 2002; 35: 126-31.
    • (2002) Hepatology , vol.35 , pp. 126-131
    • Vogel, A.1
  • 60
    • 67349255018 scopus 로고    scopus 로고
    • Vitamin D receptor polymorphisms are associated with increased susceptibility to primary biliary cirrhosis in Japanese and Italian populations
    • Tanaka A, Nezu S, Uegaki S, et al. Vitamin D receptor polymorphisms are associated with increased susceptibility to primary biliary cirrhosis in Japanese and Italian populations. J Hepatol 2009; 50: 1202-9.
    • (2009) J Hepatol , vol.50 , pp. 1202-1209
    • Tanaka, A.1    Nezu, S.2    Uegaki, S.3
  • 61
    • 84862286979 scopus 로고    scopus 로고
    • Vitamin D receptor polymorphisms predispose to primary biliary cirrhosis and severity of the disease in polish population
    • Kempinska-Podhorecka A, Wunsch E, Jarowicz T, et al. Vitamin D receptor polymorphisms predispose to primary biliary cirrhosis and severity of the disease in polish population. Gastroenterol Res Pract 2012; 2012: 408723.
    • (2012) Gastroenterol Res Pract , vol.2012 , pp. 408723
    • Kempinska-Podhorecka, A.1    Wunsch, E.2    Jarowicz, T.3
  • 62
    • 77954546984 scopus 로고    scopus 로고
    • Vitamin D receptor gene polymorphisms and hepatocellular carcinoma in alcoholic cirrhosis
    • Falleti E. Vitamin D receptor gene polymorphisms and hepatocellular carcinoma in alcoholic cirrhosis. World J Gastroenterol 2010; 16: 3016.
    • (2010) World J Gastroenterol , vol.16 , pp. 3016
    • Falleti, E.1
  • 63
    • 77950624679 scopus 로고    scopus 로고
    • Low vitamin D serum level is related to severe fibrosis and low responsiveness to interferon-based therapy in genotype 1 chronic hepatitis C
    • Petta S, Camma C, Scazzone C, et al. Low vitamin D serum level is related to severe fibrosis and low responsiveness to interferon-based therapy in genotype 1 chronic hepatitis C. Hepatology 2010; 51: 1158-67.
    • (2010) Hepatology , vol.51 , pp. 1158-1167
    • Petta, S.1    Camma, C.2    Scazzone, C.3
  • 64
    • 79953733132 scopus 로고    scopus 로고
    • Complementary role of vitamin D deficiency and the interleukin-28B rs12979860 C/T polymorphism in predicting antiviral response in chronic hepatitis C
    • Bitetto D, Fattovich G, Fabris C, et al. Complementary role of vitamin D deficiency and the interleukin-28B rs12979860 C/T polymorphism in predicting antiviral response in chronic hepatitis C. Hepatology 2011; 53: 1118-26.
    • (2011) Hepatology , vol.53 , pp. 1118-1126
    • Bitetto, D.1    Fattovich, G.2    Fabris, C.3
  • 65
    • 79960445022 scopus 로고    scopus 로고
    • Impact of artificial sunlight therapy on the progress of non-alcoholic fatty liver disease in rats
    • Nakano T, Cheng YF, Lai CY, et al. Impact of artificial sunlight therapy on the progress of non-alcoholic fatty liver disease in rats. J Hepatol 2011; 55: 415-25.
    • (2011) J Hepatol , vol.55 , pp. 415-425
    • Nakano, T.1    Cheng, Y.F.2    Lai, C.Y.3
  • 67
    • 26044480987 scopus 로고    scopus 로고
    • Evaluation and management of osteoporosis in liver disease
    • Hay JE, Guichelaar MM. Evaluation and management of osteoporosis in liver disease. Clin Liver Dis 2005; 9: 747-66.
    • (2005) Clin Liver Dis , vol.9 , pp. 747-766
    • Hay, J.E.1    Guichelaar, M.M.2
  • 68
    • 2142708118 scopus 로고    scopus 로고
    • US and UK guidelines for glucocorticoid-induced osteoporosis: similarities and differences
    • Compston J. US and UK guidelines for glucocorticoid-induced osteoporosis: similarities and differences. Curr Rheumatol Rep 2004; 6: 66-9.
    • (2004) Curr Rheumatol Rep , vol.6 , pp. 66-69
    • Compston, J.1
  • 69
    • 82455162634 scopus 로고    scopus 로고
    • Effects of bilirubin and sera from jaundiced patients on osteoblasts: contribution to the development of osteoporosis in liver diseases
    • Ruiz-Gaspa S, Martinez-Ferrer A, Guanabens N, et al. Effects of bilirubin and sera from jaundiced patients on osteoblasts: contribution to the development of osteoporosis in liver diseases. Hepatology 2011; 54: 2104-13.
    • (2011) Hepatology , vol.54 , pp. 2104-2113
    • Ruiz-Gaspa, S.1    Martinez-Ferrer, A.2    Guanabens, N.3
  • 70
    • 79551544235 scopus 로고    scopus 로고
    • Bone disorders in chronic liver diseases
    • Luxon BA. Bone disorders in chronic liver diseases. Curr Gastroenterol Rep 2011; 13: 40-48.
    • (2011) Curr Gastroenterol Rep , vol.13 , pp. 40-48
    • Luxon, B.A.1
  • 72
    • 36348985084 scopus 로고    scopus 로고
    • Bone disorders in chronic liver disease
    • Collier J. Bone disorders in chronic liver disease. Hepatology 2007; 46: 1271-8.
    • (2007) Hepatology , vol.46 , pp. 1271-1278
    • Collier, J.1
  • 73
    • 0034844053 scopus 로고    scopus 로고
    • Bone disease in primary biliary cirrhosis: independent indicators and rate of progression
    • Menon KV, Angulo P, Weston S, Dickson ER, Lindor KD. Bone disease in primary biliary cirrhosis: independent indicators and rate of progression. J Hepatol 2001; 35: 316-23.
    • (2001) J Hepatol , vol.35 , pp. 316-323
    • Menon, K.V.1    Angulo, P.2    Weston, S.3    Dickson, E.R.4    Lindor, K.D.5
  • 74
    • 0027976130 scopus 로고
    • Hepatic osteodystrophy in primary biliary cirrhosis: effects of medical treatment
    • Crippin JS, Jorgensen RA, Dickson ER, Lindor KD. Hepatic osteodystrophy in primary biliary cirrhosis: effects of medical treatment. Am J Gastroenterol 1994; 89: 47-50.
    • (1994) Am J Gastroenterol , vol.89 , pp. 47-50
    • Crippin, J.S.1    Jorgensen, R.A.2    Dickson, E.R.3    Lindor, K.D.4
  • 75
    • 0032958717 scopus 로고    scopus 로고
    • Calcitriol for bone loss in patients with primary biliary cirrhosis
    • Shiomi S, Masaki K, Habu D, et al. Calcitriol for bone loss in patients with primary biliary cirrhosis. J Gastroenterol 1999; 34: 241-5.
    • (1999) J Gastroenterol , vol.34 , pp. 241-245
    • Shiomi, S.1    Masaki, K.2    Habu, D.3
  • 77
    • 0036788277 scopus 로고    scopus 로고
    • Fas enhances fibrogenesis in the bile duct ligated mouse: A link between apoptosis and fibrosis
    • Canbay A, Higuchi H, Bronk SF, et al. Fas enhances fibrogenesis in the bile duct ligated mouse: A link between apoptosis and fibrosis. Gastroenterology 2002; 123: 1323-30.
    • (2002) Gastroenterology , vol.123 , pp. 1323-1330
    • Canbay, A.1    Higuchi, H.2    Bronk, S.F.3
  • 78
    • 0034599681 scopus 로고    scopus 로고
    • In vitro and in vivo inhibition of liver cancer cells by 1,25-dihydroxyvitamin D3
    • Pourgholami MH, Akhter J, Lu Y, Morris DL. In vitro and in vivo inhibition of liver cancer cells by 1, 25-dihydroxyvitamin D3. Cancer Lett 2000; 151: 97-102.
    • (2000) Cancer Lett , vol.151 , pp. 97-102
    • Pourgholami, M.H.1    Akhter, J.2    Lu, Y.3    Morris, D.L.4
  • 79
    • 34250203601 scopus 로고    scopus 로고
    • Overexpression of vitamin D receptor indicates a good prognosis for cholangiocarcinoma
    • Seubwai W, Wongkham C, Puapairoj A, Khuntikeo N, Wongkham S. Overexpression of vitamin D receptor indicates a good prognosis for cholangiocarcinoma. Cancer 2007; 109: 2497-505.
    • (2007) Cancer , vol.109 , pp. 2497-2505
    • Seubwai, W.1    Wongkham, C.2    Puapairoj, A.3    Khuntikeo, N.4    Wongkham, S.5
  • 80
    • 79955931061 scopus 로고    scopus 로고
    • Vitamin D deficiency in cirrhosis relates to liver dysfunction rather than aetiology
    • Malham M. Vitamin D deficiency in cirrhosis relates to liver dysfunction rather than aetiology. World J Gastroenterol 2011; 17: 922.
    • (2011) World J Gastroenterol , vol.17 , pp. 922
    • Malham, M.1
  • 81
    • 79954669573 scopus 로고    scopus 로고
    • Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferon-alfa based therapy
    • Lange CM, Bojunga J, Ramos-Lopez E, et al. Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferon-alfa based therapy. J Hepatol 2011; 54: 887-93.
    • (2011) J Hepatol , vol.54 , pp. 887-893
    • Lange, C.M.1    Bojunga, J.2    Ramos-Lopez, E.3
  • 82
    • 78650008697 scopus 로고    scopus 로고
    • Vitamin D supplementation improves response to antiviral treatment for recurrent hepatitis C
    • Bitetto D, Fabris C, Fornasiere E, et al. Vitamin D supplementation improves response to antiviral treatment for recurrent hepatitis C. Transpl Int 2011; 24: 43-50.
    • (2011) Transpl Int , vol.24 , pp. 43-50
    • Bitetto, D.1    Fabris, C.2    Fornasiere, E.3
  • 83
    • 78650751326 scopus 로고    scopus 로고
    • Vitamin D supplement improves svr in chronic hepatitis C (genotype 1) naive patients treated with PEG interferon and ribavirin [Abstract]
    • Abu Mouch SFZ, Jarchovsky J, Assy N. Vitamin D supplement improves svr in chronic hepatitis C (genotype 1) naive patients treated with PEG interferon and ribavirin [Abstract]. J Hepatol 2010; 52: S23-41.
    • (2010) J Hepatol , vol.52
    • Abu Mouch, S.F.Z.1    Jarchovsky, J.2    Assy, N.3
  • 84
    • 77949873898 scopus 로고    scopus 로고
    • Vitamin D controls T cell antigen receptor signaling and activation of human T cells
    • Von Essen MR, Kongsbak M, Schjerling P, et al. Vitamin D controls T cell antigen receptor signaling and activation of human T cells. Nat Immunol 2010; 11: 344-9.
    • (2010) Nat Immunol , vol.11 , pp. 344-349
    • Von Essen, M.R.1    Kongsbak, M.2    Schjerling, P.3
  • 85
    • 80053923183 scopus 로고    scopus 로고
    • Effects of supplemental vitamin D and calcium on biomarkers of inflammation in colorectal adenoma patients: a randomized, controlled clinical trial
    • Hopkins MH, Owen J, Ahearn T, et al. Effects of supplemental vitamin D and calcium on biomarkers of inflammation in colorectal adenoma patients: a randomized, controlled clinical trial. Cancer Prev Res (Phila) 2011; 4: 1645-54.
    • (2011) Cancer Prev Res (Phila) , vol.4 , pp. 1645-1654
    • Hopkins, M.H.1    Owen, J.2    Ahearn, T.3
  • 86
    • 16544381338 scopus 로고    scopus 로고
    • Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease
    • Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 2004; 80(6 Suppl): 1678S-88S.
    • (2004) Am J Clin Nutr , vol.80 , Issue.6 SUPPL
    • Holick, M.F.1
  • 87
    • 70350094557 scopus 로고    scopus 로고
    • Prevalence of vitamin K and vitamin D deficiency in patients with hepatobiliary and pancreatic disorders
    • Fisher L, Byrnes E, Fisher AA. Prevalence of vitamin K and vitamin D deficiency in patients with hepatobiliary and pancreatic disorders. Nutr Res 2009; 29: 676-83.
    • (2009) Nutr Res , vol.29 , pp. 676-683
    • Fisher, L.1    Byrnes, E.2    Fisher, A.A.3


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