메뉴 건너뛰기




Volumn 46, Issue , 2013, Pages 66-73

Role of the intestinal microbiome in liver disease

Author keywords

Innate immune system; Microbiota; Non alcoholic fatty liver disease; Primary biliary cirrhosis

Indexed keywords

INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; PATTERN RECOGNITION RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9;

EID: 84886284340     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2013.07.001     Document Type: Review
Times cited : (146)

References (108)
  • 1
    • 84874587195 scopus 로고    scopus 로고
    • Role of gut microbiota in liver diseases
    • Miyake Y., Yamamoto K. Role of gut microbiota in liver diseases. Hepatol Res 2012.
    • (2012) Hepatol Res
    • Miyake, Y.1    Yamamoto, K.2
  • 2
    • 84866167497 scopus 로고    scopus 로고
    • Reciprocal interactions of the intestinal microbiota and immune system
    • Maynard C.L., Elson C.O., Hatton R.D., Weaver C.T. Reciprocal interactions of the intestinal microbiota and immune system. Nature 2012, 489:231-241.
    • (2012) Nature , vol.489 , pp. 231-241
    • Maynard, C.L.1    Elson, C.O.2    Hatton, R.D.3    Weaver, C.T.4
  • 3
    • 84866168894 scopus 로고    scopus 로고
    • Functional interactions between the gut microbiota and host metabolism
    • Tremaroli V., Backhed F. Functional interactions between the gut microbiota and host metabolism. Nature 2012, 489:242-249.
    • (2012) Nature , vol.489 , pp. 242-249
    • Tremaroli, V.1    Backhed, F.2
  • 5
  • 7
    • 84857282231 scopus 로고    scopus 로고
    • Toll-like receptor-gut microbiota interactions: perturb at your own risk!
    • Carvalho F.A., Aitken J.D., Vijay-Kumar M., Gewirtz A.T. Toll-like receptor-gut microbiota interactions: perturb at your own risk!. Annu Rev Physiol 2012, 74:177-198.
    • (2012) Annu Rev Physiol , vol.74 , pp. 177-198
    • Carvalho, F.A.1    Aitken, J.D.2    Vijay-Kumar, M.3    Gewirtz, A.T.4
  • 8
    • 68149091349 scopus 로고    scopus 로고
    • Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism
    • Slack E., Hapfelmeier S., Stecher B., Velykoredko Y., Stoel M., Lawson M.A., et al. Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. Science 2009, 325:617-620.
    • (2009) Science , vol.325 , pp. 617-620
    • Slack, E.1    Hapfelmeier, S.2    Stecher, B.3    Velykoredko, Y.4    Stoel, M.5    Lawson, M.A.6
  • 9
    • 33845367541 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity in gut homeostasis and pathology
    • Michelsen K.S., Arditi M. Toll-like receptors and innate immunity in gut homeostasis and pathology. Curr Opin Hematol 2007, 14:48-54.
    • (2007) Curr Opin Hematol , vol.14 , pp. 48-54
    • Michelsen, K.S.1    Arditi, M.2
  • 10
    • 33846492518 scopus 로고    scopus 로고
    • Regulation of Toll-like receptor-2 expression in chronic hepatitis B by the precore protein
    • Visvanathan K., Skinner N.A., Thompson A.J., Riordan S.M., Sozzi V., Edwards R., et al. Regulation of Toll-like receptor-2 expression in chronic hepatitis B by the precore protein. Hepatology 2007, 45:102-110.
    • (2007) Hepatology , vol.45 , pp. 102-110
    • Visvanathan, K.1    Skinner, N.A.2    Thompson, A.J.3    Riordan, S.M.4    Sozzi, V.5    Edwards, R.6
  • 11
    • 84155178352 scopus 로고    scopus 로고
    • Toll-like receptor 2-mediated innate immune response in human nonparenchymal liver cells toward adeno-associated viral vectors
    • Hosel M., Broxtermann M., Janicki H., Esser K., Arzberger S., Hartmann P., et al. Toll-like receptor 2-mediated innate immune response in human nonparenchymal liver cells toward adeno-associated viral vectors. Hepatology 2012, 55:287-297.
    • (2012) Hepatology , vol.55 , pp. 287-297
    • Hosel, M.1    Broxtermann, M.2    Janicki, H.3    Esser, K.4    Arzberger, S.5    Hartmann, P.6
  • 12
    • 71549122264 scopus 로고    scopus 로고
    • Toll-like receptor activated human and murine hepatic stellate cells are potent regulators of hepatitis C virus replication
    • Wang B., Trippler M., Pei R., Lu M., Broering R., Gerken G., et al. Toll-like receptor activated human and murine hepatic stellate cells are potent regulators of hepatitis C virus replication. JHepatol 2009, 51:1037-1045.
    • (2009) JHepatol , vol.51 , pp. 1037-1045
    • Wang, B.1    Trippler, M.2    Pei, R.3    Lu, M.4    Broering, R.5    Gerken, G.6
  • 13
    • 33645741989 scopus 로고    scopus 로고
    • Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways
    • Yokoyama T., Komori A., Nakamura M., Takii Y., Kamihira T., Shimoda S., et al. Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways. Liver Int 2006, 26:467-476.
    • (2006) Liver Int , vol.26 , pp. 467-476
    • Yokoyama, T.1    Komori, A.2    Nakamura, M.3    Takii, Y.4    Kamihira, T.5    Shimoda, S.6
  • 14
    • 22444442654 scopus 로고    scopus 로고
    • Hepatic expression of toll-like receptor 4 in primary biliary cirrhosis
    • Wang A.P., Migita K., Ito M., Takii Y., Daikoku M., Yokoyama T., et al. Hepatic expression of toll-like receptor 4 in primary biliary cirrhosis. JAutoimmun 2005, 25:85-91.
    • (2005) JAutoimmun , vol.25 , pp. 85-91
    • Wang, A.P.1    Migita, K.2    Ito, M.3    Takii, Y.4    Daikoku, M.5    Yokoyama, T.6
  • 15
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
    • Kawai T., Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010, 11:373-384.
    • (2010) Nat Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 17
    • 49449083979 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intake
    • Thuy S., Ladurner R., Volynets V., Wagner S., Strahl S., Konigsrainer A., et al. Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intake. JNutr 2008, 138:1452-1455.
    • (2008) JNutr , vol.138 , pp. 1452-1455
    • Thuy, S.1    Ladurner, R.2    Volynets, V.3    Wagner, S.4    Strahl, S.5    Konigsrainer, A.6
  • 18
    • 80053991368 scopus 로고    scopus 로고
    • Enhanced innate immune responsiveness and intolerance to intestinal endotoxins in human biliary epithelial cells contributes to chronic cholangitis
    • Mueller T., Beutler C., Pico A.H., Shibolet O., Pratt D.S., Pascher A., et al. Enhanced innate immune responsiveness and intolerance to intestinal endotoxins in human biliary epithelial cells contributes to chronic cholangitis. Liver Int 2011, 31:1574-1588.
    • (2011) Liver Int , vol.31 , pp. 1574-1588
    • Mueller, T.1    Beutler, C.2    Pico, A.H.3    Shibolet, O.4    Pratt, D.S.5    Pascher, A.6
  • 19
    • 80055043169 scopus 로고    scopus 로고
    • Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice
    • Li L., Chen L., Hu L., Liu Y., Sun H.Y., Tang J., et al. Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice. Hepatology 2011, 54:1620-1630.
    • (2011) Hepatology , vol.54 , pp. 1620-1630
    • Li, L.1    Chen, L.2    Hu, L.3    Liu, Y.4    Sun, H.Y.5    Tang, J.6
  • 20
    • 34548301514 scopus 로고    scopus 로고
    • A7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C
    • Huang H., Shiffman M.L., Friedman S., Venkatesh R., Bzowej N., Abar O.T., et al. A7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C. Hepatology 2007, 46:297-306.
    • (2007) Hepatology , vol.46 , pp. 297-306
    • Huang, H.1    Shiffman, M.L.2    Friedman, S.3    Venkatesh, R.4    Bzowej, N.5    Abar, O.T.6
  • 21
    • 84860340474 scopus 로고    scopus 로고
    • The Asp299Gly polymorphism alters TLR4 signaling by interfering with recruitment of MyD88 and TRIF
    • Figueroa L., Xiong Y., Song C., Piao W., Vogel S.N., Medvedev A.E. The Asp299Gly polymorphism alters TLR4 signaling by interfering with recruitment of MyD88 and TRIF. JImmunol 2012, 188:4506-4515.
    • (2012) JImmunol , vol.188 , pp. 4506-4515
    • Figueroa, L.1    Xiong, Y.2    Song, C.3    Piao, W.4    Vogel, S.N.5    Medvedev, A.E.6
  • 22
    • 79251600358 scopus 로고    scopus 로고
    • Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice
    • e4
    • Petrasek J., Dolganiuc A., Csak T., Kurt-Jones E.A., Szabo G. Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice. Gastroenterology 2011, 140:697-708. e4.
    • (2011) Gastroenterology , vol.140 , pp. 697-708
    • Petrasek, J.1    Dolganiuc, A.2    Csak, T.3    Kurt-Jones, E.A.4    Szabo, G.5
  • 23
    • 79251482742 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells
    • Petrasek J., Dolganiuc A., Csak T., Nath B., Hritz I., Kodys K., et al. Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells. Hepatology 2011, 53:649-660.
    • (2011) Hepatology , vol.53 , pp. 649-660
    • Petrasek, J.1    Dolganiuc, A.2    Csak, T.3    Nath, B.4    Hritz, I.5    Kodys, K.6
  • 25
    • 84856957894 scopus 로고    scopus 로고
    • Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
    • Henao-Mejia J., Elinav E., Jin C., Hao L., Mehal W.Z., Strowig T., et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 2012, 482:179-185.
    • (2012) Nature , vol.482 , pp. 179-185
    • Henao-Mejia, J.1    Elinav, E.2    Jin, C.3    Hao, L.4    Mehal, W.Z.5    Strowig, T.6
  • 26
    • 84866180909 scopus 로고    scopus 로고
    • Gut-derived lipopolysaccharide promotes T-cell-mediated hepatitis in mice through Toll-like receptor 4
    • Lin Y., Yu L.X., Yan H.X., Yang W., Tang L., Zhang H.L., et al. Gut-derived lipopolysaccharide promotes T-cell-mediated hepatitis in mice through Toll-like receptor 4. Cancer Prev Res (Phila) 2012, 5:1090-1102.
    • (2012) Cancer Prev Res (Phila) , vol.5 , pp. 1090-1102
    • Lin, Y.1    Yu, L.X.2    Yan, H.X.3    Yang, W.4    Tang, L.5    Zhang, H.L.6
  • 29
    • 77249118801 scopus 로고    scopus 로고
    • The inflammasomes: mechanisms of activation and function
    • Latz E. The inflammasomes: mechanisms of activation and function. Curr Opin Immunol 2010, 22:28-33.
    • (2010) Curr Opin Immunol , vol.22 , pp. 28-33
    • Latz, E.1
  • 30
    • 79956303498 scopus 로고    scopus 로고
    • Regulation of the antimicrobial response by NLR proteins
    • Elinav E., Strowig T., Henao-Mejia J., Flavell R.A. Regulation of the antimicrobial response by NLR proteins. Immunity 2011, 34:665-679.
    • (2011) Immunity , vol.34 , pp. 665-679
    • Elinav, E.1    Strowig, T.2    Henao-Mejia, J.3    Flavell, R.A.4
  • 31
    • 84870062861 scopus 로고    scopus 로고
    • Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease
    • Boaru S.G., Borkham-Kamphorst E., Tihaa L., Haas U., Weiskirchen R. Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease. JInflamm (Lond) 2012, 9:49.
    • (2012) JInflamm (Lond) , vol.9 , pp. 49
    • Boaru, S.G.1    Borkham-Kamphorst, E.2    Tihaa, L.3    Haas, U.4    Weiskirchen, R.5
  • 33
    • 77955922658 scopus 로고    scopus 로고
    • Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injury
    • Williams C.D., Farhood A., Jaeschke H. Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injury. Toxicol Appl Pharmacol 2010, 247:169-178.
    • (2010) Toxicol Appl Pharmacol , vol.247 , pp. 169-178
    • Williams, C.D.1    Farhood, A.2    Jaeschke, H.3
  • 35
    • 79960371987 scopus 로고    scopus 로고
    • Gene silencing of NALP3 protects against liver ischemia-reperfusion injury in mice
    • Zhu P., Duan L., Chen J., Xiong A., Xu Q., Zhang H., et al. Gene silencing of NALP3 protects against liver ischemia-reperfusion injury in mice. Hum Gene Ther 2011, 22:853-864.
    • (2011) Hum Gene Ther , vol.22 , pp. 853-864
    • Zhu, P.1    Duan, L.2    Chen, J.3    Xiong, A.4    Xu, Q.5    Zhang, H.6
  • 36
    • 77954582426 scopus 로고    scopus 로고
    • The TLR4/TRIF-mediated activation of NLRP3 inflammasome underlies endotoxin-induced liver injury in mice
    • Tsutsui H., Imamura M., Fujimoto J., Nakanishi K. The TLR4/TRIF-mediated activation of NLRP3 inflammasome underlies endotoxin-induced liver injury in mice. Gastroenterol Res Pract 2010, 2010:641865.
    • (2010) Gastroenterol Res Pract , vol.2010 , pp. 641865
    • Tsutsui, H.1    Imamura, M.2    Fujimoto, J.3    Nakanishi, K.4
  • 37
    • 78650544477 scopus 로고    scopus 로고
    • Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses
    • Ritter M., Gross O., Kays S., Ruland J., Nimmerjahn F., Saijo S., et al. Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses. Proc Natl Acad Sci U S A 2010, 107:20459-20464.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 20459-20464
    • Ritter, M.1    Gross, O.2    Kays, S.3    Ruland, J.4    Nimmerjahn, F.5    Saijo, S.6
  • 38
    • 79959573042 scopus 로고    scopus 로고
    • Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
    • Csak T., Ganz M., Pespisa J., Kodys K., Dolganiuc A., Szabo G. Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells. Hepatology 2011, 54:133-144.
    • (2011) Hepatology , vol.54 , pp. 133-144
    • Csak, T.1    Ganz, M.2    Pespisa, J.3    Kodys, K.4    Dolganiuc, A.5    Szabo, G.6
  • 39
    • 82455205872 scopus 로고    scopus 로고
    • Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver
    • Ganz M., Csak T., Nath B., Szabo G. Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver. World J Gastroenterol 2011, 17:4772-4778.
    • (2011) World J Gastroenterol , vol.17 , pp. 4772-4778
    • Ganz, M.1    Csak, T.2    Nath, B.3    Szabo, G.4
  • 41
    • 84866461477 scopus 로고    scopus 로고
    • Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice
    • Ubeda C., Lipuma L., Gobourne A., Viale A., Leiner I., Equinda M., et al. Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice. JExp Med 2012, 209:1445-1456.
    • (2012) JExp Med , vol.209 , pp. 1445-1456
    • Ubeda, C.1    Lipuma, L.2    Gobourne, A.3    Viale, A.4    Leiner, I.5    Equinda, M.6
  • 42
    • 79957576718 scopus 로고    scopus 로고
    • NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
    • Elinav E., Strowig T., Kau A.L., Henao-Mejia J., Thaiss C.A., Booth C.J., et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 2011, 145:745-757.
    • (2011) Cell , vol.145 , pp. 745-757
    • Elinav, E.1    Strowig, T.2    Kau, A.L.3    Henao-Mejia, J.4    Thaiss, C.A.5    Booth, C.J.6
  • 43
    • 77953724339 scopus 로고    scopus 로고
    • The changing pattern of epidemiology in hepatocellular carcinoma
    • Nordenstedt H., White D.L., El-Serag H.B. The changing pattern of epidemiology in hepatocellular carcinoma. Dig Liver Dis 2010, 42(Suppl.3):S206-S214.
    • (2010) Dig Liver Dis , vol.42 , Issue.SUPPL.3
    • Nordenstedt, H.1    White, D.L.2    El-Serag, H.B.3
  • 45
    • 33644630329 scopus 로고    scopus 로고
    • Primary sclerosing cholangitis: epidemiology, natural history, and prognosis
    • Levy C., Lindor K.D. Primary sclerosing cholangitis: epidemiology, natural history, and prognosis. Semin Liver Dis 2006, 26:22-30.
    • (2006) Semin Liver Dis , vol.26 , pp. 22-30
    • Levy, C.1    Lindor, K.D.2
  • 47
    • 80051540039 scopus 로고    scopus 로고
    • Clinical characteristics of ulcerative colitis associated with primary sclerosing cholangitis in Korea
    • Ye B.D., Yang S.K., Boo S.J., Cho Y.K., Yang D.H., Yoon S.M., et al. Clinical characteristics of ulcerative colitis associated with primary sclerosing cholangitis in Korea. Inflamm Bowel Dis 2011, 17:1901-1906.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1901-1906
    • Ye, B.D.1    Yang, S.K.2    Boo, S.J.3    Cho, Y.K.4    Yang, D.H.5    Yoon, S.M.6
  • 48
    • 0027410478 scopus 로고
    • Prevalence of primary sclerosing cholangitis and other liver diseases in Japanese patients with chronic ulcerative colitis
    • Hashimoto E., Ideta M., Taniai M., Watanabe U., Okuda H., Nagasako K., et al. Prevalence of primary sclerosing cholangitis and other liver diseases in Japanese patients with chronic ulcerative colitis. JGastroenterol Hepatol 1993, 8:146-149.
    • (1993) JGastroenterol Hepatol , vol.8 , pp. 146-149
    • Hashimoto, E.1    Ideta, M.2    Taniai, M.3    Watanabe, U.4    Okuda, H.5    Nagasako, K.6
  • 49
    • 47949124659 scopus 로고    scopus 로고
    • Increased risk of primary sclerosing cholangitis and ulcerative colitis in first-degree relatives of patients with primary sclerosing cholangitis
    • Bergquist A., Montgomery S.M., Bahmanyar S., Olsson R., Danielsson A., Lindgren S., et al. Increased risk of primary sclerosing cholangitis and ulcerative colitis in first-degree relatives of patients with primary sclerosing cholangitis. Clin Gastroenterol Hepatol 2008, 6:939-943.
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 939-943
    • Bergquist, A.1    Montgomery, S.M.2    Bahmanyar, S.3    Olsson, R.4    Danielsson, A.5    Lindgren, S.6
  • 50
    • 0242490278 scopus 로고    scopus 로고
    • Incidence, clinical spectrum, and outcomes of primary sclerosing cholangitis in a United States community
    • Bambha K., Kim W.R., Talwalkar J., Torgerson H., Benson J.T., Therneau T.M., et al. Incidence, clinical spectrum, and outcomes of primary sclerosing cholangitis in a United States community. Gastroenterology 2003, 125:1364-1369.
    • (2003) Gastroenterology , vol.125 , pp. 1364-1369
    • Bambha, K.1    Kim, W.R.2    Talwalkar, J.3    Torgerson, H.4    Benson, J.T.5    Therneau, T.M.6
  • 51
    • 79959844176 scopus 로고    scopus 로고
    • Clinical characteristics of inflammatory bowel disease associated with primary sclerosing cholangitis
    • Sano H., Nakazawa T., Ando T., Hayashi K., Naitoh I., Okumura F., et al. Clinical characteristics of inflammatory bowel disease associated with primary sclerosing cholangitis. JHepatobiliary Pancreat Sci 2011, 18:154-161.
    • (2011) JHepatobiliary Pancreat Sci , vol.18 , pp. 154-161
    • Sano, H.1    Nakazawa, T.2    Ando, T.3    Hayashi, K.4    Naitoh, I.5    Okumura, F.6
  • 52
    • 67549107974 scopus 로고    scopus 로고
    • Pathologic features of ulcerative colitis in patients with primary sclerosing cholangitis: a case-control study
    • Joo M., Abreu-e-Lima P., Farraye F., Smith T., Swaroop P., Gardner L., et al. Pathologic features of ulcerative colitis in patients with primary sclerosing cholangitis: a case-control study. Am J Surg Pathol 2009, 33:854-862.
    • (2009) Am J Surg Pathol , vol.33 , pp. 854-862
    • Joo, M.1    Abreu-e-Lima, P.2    Farraye, F.3    Smith, T.4    Swaroop, P.5    Gardner, L.6
  • 53
    • 67349123124 scopus 로고    scopus 로고
    • Influence of dominant bile duct stenoses and biliary infections on outcome in primary sclerosing cholangitis
    • Rudolph G., Gotthardt D., Kloters-Plachky P., Kulaksiz H., Rost D., Stiehl A. Influence of dominant bile duct stenoses and biliary infections on outcome in primary sclerosing cholangitis. JHepatol 2009, 51:149-155.
    • (2009) JHepatol , vol.51 , pp. 149-155
    • Rudolph, G.1    Gotthardt, D.2    Kloters-Plachky, P.3    Kulaksiz, H.4    Rost, D.5    Stiehl, A.6
  • 54
  • 55
    • 0031879553 scopus 로고    scopus 로고
    • Atypical antineutrophil cytoplasmic antibodies with perinuclear fluorescence in chronic inflammatory bowel diseases and hepatobiliary disorders colocalize with nuclear lamina proteins
    • Terjung B., Herzog V., Worman H.J., Gestmann I., Bauer C., Sauerbruch T., et al. Atypical antineutrophil cytoplasmic antibodies with perinuclear fluorescence in chronic inflammatory bowel diseases and hepatobiliary disorders colocalize with nuclear lamina proteins. Hepatology 1998, 28:332-340.
    • (1998) Hepatology , vol.28 , pp. 332-340
    • Terjung, B.1    Herzog, V.2    Worman, H.J.3    Gestmann, I.4    Bauer, C.5    Sauerbruch, T.6
  • 56
    • 77953718694 scopus 로고    scopus 로고
    • P-ANCAs in autoimmune liver disorders recognise human beta-tubulin isotype 5 and cross-react with microbial protein FtsZ
    • Terjung B., Sohne J., Lechtenberg B., Gottwein J., Muennich M., Herzog V., et al. p-ANCAs in autoimmune liver disorders recognise human beta-tubulin isotype 5 and cross-react with microbial protein FtsZ. Gut 2010, 59:808-816.
    • (2010) Gut , vol.59 , pp. 808-816
    • Terjung, B.1    Sohne, J.2    Lechtenberg, B.3    Gottwein, J.4    Muennich, M.5    Herzog, V.6
  • 57
    • 34248376881 scopus 로고    scopus 로고
    • Autoimmune liver disease: overlap and outliers
    • Washington M.K. Autoimmune liver disease: overlap and outliers. Mod Pathol 2007, 20(Suppl.1):S15-S30.
    • (2007) Mod Pathol , vol.20 , Issue.SUPPL.1
    • Washington, M.K.1
  • 58
    • 0024843644 scopus 로고
    • Relation between Escherichia coli R(rough)-forms in gut, lipid A in liver, and primary biliary cirrhosis
    • Hopf U., Moller B., Stemerowicz R., Lobeck H., Rodloff A., Freudenberg M., et al. Relation between Escherichia coli R(rough)-forms in gut, lipid A in liver, and primary biliary cirrhosis. Lancet 1989, 2:1419-1422.
    • (1989) Lancet , vol.2 , pp. 1419-1422
    • Hopf, U.1    Moller, B.2    Stemerowicz, R.3    Lobeck, H.4    Rodloff, A.5    Freudenberg, M.6
  • 59
    • 0346689993 scopus 로고    scopus 로고
    • Microbial mimics are major targets of crossreactivity with human pyruvate dehydrogenase in primary biliary cirrhosis
    • Bogdanos D.P., Baum H., Grasso A., Okamoto M., Butler P., Ma Y., et al. Microbial mimics are major targets of crossreactivity with human pyruvate dehydrogenase in primary biliary cirrhosis. JHepatol 2004, 40:31-39.
    • (2004) JHepatol , vol.40 , pp. 31-39
    • Bogdanos, D.P.1    Baum, H.2    Grasso, A.3    Okamoto, M.4    Butler, P.5    Ma, Y.6
  • 60
    • 23044467085 scopus 로고    scopus 로고
    • Primary biliary cirrhosis is characterized by IgG3 antibodies cross-reactive with the major mitochondrial autoepitope and its Lactobacillus mimic
    • Bogdanos D.P., Baum H., Okamoto M., Montalto P., Sharma U.C., Rigopoulou E.I., et al. Primary biliary cirrhosis is characterized by IgG3 antibodies cross-reactive with the major mitochondrial autoepitope and its Lactobacillus mimic. Hepatology 2005, 42:458-465.
    • (2005) Hepatology , vol.42 , pp. 458-465
    • Bogdanos, D.P.1    Baum, H.2    Okamoto, M.3    Montalto, P.4    Sharma, U.C.5    Rigopoulou, E.I.6
  • 61
    • 0142182773 scopus 로고    scopus 로고
    • Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium
    • Selmi C., Balkwill D.L., Invernizzi P., Ansari A.A., Coppel R.L., Podda M., et al. Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium. Hepatology 2003, 38:1250-1257.
    • (2003) Hepatology , vol.38 , pp. 1250-1257
    • Selmi, C.1    Balkwill, D.L.2    Invernizzi, P.3    Ansari, A.A.4    Coppel, R.L.5    Podda, M.6
  • 63
    • 0019152816 scopus 로고
    • Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease
    • Ludwig J., Viggiano T.R., McGill D.B., Oh B.J. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980, 55:434-438.
    • (1980) Mayo Clin Proc , vol.55 , pp. 434-438
    • Ludwig, J.1    Viggiano, T.R.2    McGill, D.B.3    Oh, B.J.4
  • 65
    • 33847629709 scopus 로고    scopus 로고
    • Spectrum of liver disease in type 2 diabetes and management of patients with diabetes and liver disease
    • Tolman K.G., Fonseca V., Dalpiaz A., Tan M.H. Spectrum of liver disease in type 2 diabetes and management of patients with diabetes and liver disease. Diabetes Care 2007, 30:734-743.
    • (2007) Diabetes Care , vol.30 , pp. 734-743
    • Tolman, K.G.1    Fonseca, V.2    Dalpiaz, A.3    Tan, M.H.4
  • 68
    • 0035991455 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in patients with non-alcoholic steatohepatitis
    • Shimada M., Hashimoto E., Taniai M., Hasegawa K., Okuda H., Hayashi N., et al. Hepatocellular carcinoma in patients with non-alcoholic steatohepatitis. JHepatol 2002, 37:154-160.
    • (2002) JHepatol , vol.37 , pp. 154-160
    • Shimada, M.1    Hashimoto, E.2    Taniai, M.3    Hasegawa, K.4    Okuda, H.5    Hayashi, N.6
  • 70
    • 43949086923 scopus 로고    scopus 로고
    • Cirrhosis and liver failure in nonalcoholic fatty liver disease: molehill or mountain?
    • Charlton M. Cirrhosis and liver failure in nonalcoholic fatty liver disease: molehill or mountain?. Hepatology 2008, 47:1431-1433.
    • (2008) Hepatology , vol.47 , pp. 1431-1433
    • Charlton, M.1
  • 72
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: a tale of two "hits"?
    • Day C.P., James O.F. Steatohepatitis: a tale of two "hits"?. Gastroenterology 1998, 114:842-845.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 74
    • 79957449923 scopus 로고    scopus 로고
    • Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008
    • e1; quiz e60
    • Younossi Z.M., Stepanova M., Afendy M., Fang Y., Younossi Y., Mir H., et al. Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008. Clin Gastroenterol Hepatol 2011, 9:524-530. e1; quiz e60.
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 524-530
    • Younossi, Z.M.1    Stepanova, M.2    Afendy, M.3    Fang, Y.4    Younossi, Y.5    Mir, H.6
  • 75
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh P.J., Ley R.E., Mahowald M.A., Magrini V., Mardis E.R., Gordon J.I. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006, 444:1027-1031.
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 77
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley R.E., Turnbaugh P.J., Klein S., Gordon J.I. Microbial ecology: human gut microbes associated with obesity. Nature 2006, 444:1022-1023.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 78
    • 79956301905 scopus 로고    scopus 로고
    • Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans
    • Muegge B.D., Kuczynski J., Knights D., Clemente J.C., Gonzalez A., Fontana L., et al. Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans. Science 2011, 332:970-974.
    • (2011) Science , vol.332 , pp. 970-974
    • Muegge, B.D.1    Kuczynski, J.2    Knights, D.3    Clemente, J.C.4    Gonzalez, A.5    Fontana, L.6
  • 79
    • 84867074831 scopus 로고    scopus 로고
    • Ametagenome-wide association study of gut microbiota in type 2 diabetes
    • Qin J., Li Y., Cai Z., Li S., Zhu J., Zhang F., et al. Ametagenome-wide association study of gut microbiota in type 2 diabetes. Nature 2012, 490:55-60.
    • (2012) Nature , vol.490 , pp. 55-60
    • Qin, J.1    Li, Y.2    Cai, Z.3    Li, S.4    Zhu, J.5    Zhang, F.6
  • 82
    • 77957075815 scopus 로고    scopus 로고
    • Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
    • De Filippo C., Cavalieri D., Di Paola M., Ramazzotti M., Poullet J.B., Massart S., et al. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A 2010, 107:14691-14696.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 14691-14696
    • De Filippo, C.1    Cavalieri, D.2    Di Paola, M.3    Ramazzotti, M.4    Poullet, J.B.5    Massart, S.6
  • 83
    • 84887614976 scopus 로고    scopus 로고
    • Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice
    • Le Roy T., Llopis M., Lepage P., Bruneau A., Rabot S., Bevilacqua C., et al. Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice. Gut 2012.
    • (2012) Gut
    • Le Roy, T.1    Llopis, M.2    Lepage, P.3    Bruneau, A.4    Rabot, S.5    Bevilacqua, C.6
  • 85
    • 34548141726 scopus 로고    scopus 로고
    • Intestinal failure-associated liver disease: management and treatment strategies past, present, and future
    • Carter B.A., Karpen S.J. Intestinal failure-associated liver disease: management and treatment strategies past, present, and future. Semin Liver Dis 2007, 27:251-258.
    • (2007) Semin Liver Dis , vol.27 , pp. 251-258
    • Carter, B.A.1    Karpen, S.J.2
  • 86
    • 0024317284 scopus 로고
    • Non-alcoholic steatohepatitis associated with small intestinal diverticulosis and bacterial overgrowth
    • Nazim M., Stamp G., Hodgson H.J. Non-alcoholic steatohepatitis associated with small intestinal diverticulosis and bacterial overgrowth. Hepatogastroenterology 1989, 36:349-351.
    • (1989) Hepatogastroenterology , vol.36 , pp. 349-351
    • Nazim, M.1    Stamp, G.2    Hodgson, H.J.3
  • 87
    • 0021402762 scopus 로고
    • Jejunoileal bypass: change in the flora of the small intestine and its clinical impact
    • Corrodi P. Jejunoileal bypass: change in the flora of the small intestine and its clinical impact. Rev Infect Dis 1984, 6(Suppl.1):S80-S84.
    • (1984) Rev Infect Dis , vol.6 , Issue.SUPPL.1
    • Corrodi, P.1
  • 88
    • 0020026596 scopus 로고
    • Effect of antibiotics in the prevention of jejunoileal bypass-induced liver dysfunction
    • Vanderhoof J.A., Tuma D.J., Antonson D.L., Sorrell M.F. Effect of antibiotics in the prevention of jejunoileal bypass-induced liver dysfunction. Digestion 1982, 23:9-15.
    • (1982) Digestion , vol.23 , pp. 9-15
    • Vanderhoof, J.A.1    Tuma, D.J.2    Antonson, D.L.3    Sorrell, M.F.4
  • 89
    • 0026564262 scopus 로고
    • Polymyxin B reduces total parenteral nutrition-associated hepatic steatosis by its antibacterial activity and by blocking deleterious effects of lipopolysaccharide
    • Pappo I., Bercovier H., Berry E.M., Haviv Y., Gallily R., Freund H.R. Polymyxin B reduces total parenteral nutrition-associated hepatic steatosis by its antibacterial activity and by blocking deleterious effects of lipopolysaccharide. JParenter Enteral Nutr 1992, 16:529-532.
    • (1992) JParenter Enteral Nutr , vol.16 , pp. 529-532
    • Pappo, I.1    Bercovier, H.2    Berry, E.M.3    Haviv, Y.4    Gallily, R.5    Freund, H.R.6
  • 90
    • 43349107591 scopus 로고    scopus 로고
    • High prevalence of small intestinal bacterial overgrowth in patients with morbid obesity: a contributor to severe hepatic steatosis
    • Sabate J.M., Jouet P., Harnois F., Mechler C., Msika S., Grossin M., et al. High prevalence of small intestinal bacterial overgrowth in patients with morbid obesity: a contributor to severe hepatic steatosis. Obes Surg 2008, 18:371-377.
    • (2008) Obes Surg , vol.18 , pp. 371-377
    • Sabate, J.M.1    Jouet, P.2    Harnois, F.3    Mechler, C.4    Msika, S.5    Grossin, M.6
  • 91
    • 68949148889 scopus 로고    scopus 로고
    • Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease
    • Miele L., Valenza V., La Torre G., Montalto M., Cammarota G., Ricci R., et al. Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease. Hepatology 2009, 49:1877-1887.
    • (2009) Hepatology , vol.49 , pp. 1877-1887
    • Miele, L.1    Valenza, V.2    La Torre, G.3    Montalto, M.4    Cammarota, G.5    Ricci, R.6
  • 92
    • 23944514253 scopus 로고    scopus 로고
    • Ciprofloxacin suppresses bacterial overgrowth, increases fasting insulin but does not correct low acylated ghrelin concentration in non-alcoholic steatohepatitis
    • Sajjad A., Mottershead M., Syn W.K., Jones R., Smith S., Nwokolo C.U. Ciprofloxacin suppresses bacterial overgrowth, increases fasting insulin but does not correct low acylated ghrelin concentration in non-alcoholic steatohepatitis. Aliment Pharmacol Ther 2005, 22:291-299.
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 291-299
    • Sajjad, A.1    Mottershead, M.2    Syn, W.K.3    Jones, R.4    Smith, S.5    Nwokolo, C.U.6
  • 93
    • 0035125052 scopus 로고    scopus 로고
    • The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis
    • Wigg A.J., Roberts-Thomson I.C., Dymock R.B., McCarthy P.J., Grose R.H., Cummins A.G. The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis. Gut 2001, 48:206-211.
    • (2001) Gut , vol.48 , pp. 206-211
    • Wigg, A.J.1    Roberts-Thomson, I.C.2    Dymock, R.B.3    McCarthy, P.J.4    Grose, R.H.5    Cummins, A.G.6
  • 94
    • 0030902779 scopus 로고    scopus 로고
    • Ammonia and GABA-ergic neurotransmission: interrelated factors in the pathogenesis of hepatic encephalopathy
    • Basile A.S., Jones E.A. Ammonia and GABA-ergic neurotransmission: interrelated factors in the pathogenesis of hepatic encephalopathy. Hepatology 1997, 25:1303-1305.
    • (1997) Hepatology , vol.25 , pp. 1303-1305
    • Basile, A.S.1    Jones, E.A.2
  • 95
    • 0030922914 scopus 로고    scopus 로고
    • Spontaneous bacterial peritonitis
    • Guarner C., Soriano G. Spontaneous bacterial peritonitis. Semin Liver Dis 1997, 17:203-217.
    • (1997) Semin Liver Dis , vol.17 , pp. 203-217
    • Guarner, C.1    Soriano, G.2
  • 98
    • 25844517166 scopus 로고    scopus 로고
    • Bacterial infection and acute bleeding from upper gastrointestinal tract in patients with liver cirrhosis
    • Husova L., Lata J., Husa P., Senkyrik M., Jurankova J., Dite P. Bacterial infection and acute bleeding from upper gastrointestinal tract in patients with liver cirrhosis. Hepatogastroenterology 2005, 52:1488-1490.
    • (2005) Hepatogastroenterology , vol.52 , pp. 1488-1490
    • Husova, L.1    Lata, J.2    Husa, P.3    Senkyrik, M.4    Jurankova, J.5    Dite, P.6
  • 99
    • 0034794067 scopus 로고    scopus 로고
    • Small intestinal bacterial overgrowth in patients with cirrhosis: prevalence and relation with spontaneous bacterial peritonitis
    • Bauer T.M., Steinbruckner B., Brinkmann F.E., Ditzen A.K., Schwacha H., Aponte J.J., et al. Small intestinal bacterial overgrowth in patients with cirrhosis: prevalence and relation with spontaneous bacterial peritonitis. Am J Gastroenterol 2001, 96:2962-2967.
    • (2001) Am J Gastroenterol , vol.96 , pp. 2962-2967
    • Bauer, T.M.1    Steinbruckner, B.2    Brinkmann, F.E.3    Ditzen, A.K.4    Schwacha, H.5    Aponte, J.J.6
  • 100
    • 0038310856 scopus 로고    scopus 로고
    • Small intestinal motility disturbances and bacterial overgrowth in patients with liver cirrhosis and portal hypertension
    • Gunnarsdottir S.A., Sadik R., Shev S., Simren M., Sjovall H., Stotzer P.O., et al. Small intestinal motility disturbances and bacterial overgrowth in patients with liver cirrhosis and portal hypertension. Am J Gastroenterol 2003, 98:1362-1370.
    • (2003) Am J Gastroenterol , vol.98 , pp. 1362-1370
    • Gunnarsdottir, S.A.1    Sadik, R.2    Shev, S.3    Simren, M.4    Sjovall, H.5    Stotzer, P.O.6
  • 101
    • 0027436696 scopus 로고
    • Antibacterial activity of bile salts against common biliary pathogens. Effects of hydrophobicity of the molecule and in the presence of phospholipids
    • Sung J.Y., Shaffer E.A., Costerton J.W. Antibacterial activity of bile salts against common biliary pathogens. Effects of hydrophobicity of the molecule and in the presence of phospholipids. Dig Dis Sci 1993, 38:2104-2112.
    • (1993) Dig Dis Sci , vol.38 , pp. 2104-2112
    • Sung, J.Y.1    Shaffer, E.A.2    Costerton, J.W.3
  • 102
    • 75749105423 scopus 로고    scopus 로고
    • Review article: the modern management of hepatic encephalopathy
    • Bajaj J.S. Review article: the modern management of hepatic encephalopathy. Aliment Pharmacol Ther 2010, 31:537-547.
    • (2010) Aliment Pharmacol Ther , vol.31 , pp. 537-547
    • Bajaj, J.S.1
  • 103
    • 33846436400 scopus 로고    scopus 로고
    • Review article: bacterial flora and pathogenesis in hepatic encephalopathy
    • Williams R. Review article: bacterial flora and pathogenesis in hepatic encephalopathy. Aliment Pharmacol Ther 2007, 25(Suppl.1):17-22.
    • (2007) Aliment Pharmacol Ther , vol.25 , Issue.SUPPL.1 , pp. 17-22
    • Williams, R.1
  • 104
    • 79751499077 scopus 로고    scopus 로고
    • Rifaximin improves psychometric performance and health-related quality of life in patients with minimal hepatic encephalopathy (the RIME Trial)
    • Sidhu S.S., Goyal O., Mishra B.P., Sood A., Chhina R.S., Soni R.K. Rifaximin improves psychometric performance and health-related quality of life in patients with minimal hepatic encephalopathy (the RIME Trial). Am J Gastroenterol 2011, 106:307-316.
    • (2011) Am J Gastroenterol , vol.106 , pp. 307-316
    • Sidhu, S.S.1    Goyal, O.2    Mishra, B.P.3    Sood, A.4    Chhina, R.S.5    Soni, R.K.6
  • 105
    • 79251535022 scopus 로고    scopus 로고
    • Rifaximin improves driving simulator performance in a randomized trial of patients with minimal hepatic encephalopathy
    • e1
    • Bajaj J.S., Heuman D.M., Wade J.B., Gibson D.P., Saeian K., Wegelin J.A., et al. Rifaximin improves driving simulator performance in a randomized trial of patients with minimal hepatic encephalopathy. Gastroenterology 2011, 140:478-487. e1.
    • (2011) Gastroenterology , vol.140 , pp. 478-487
    • Bajaj, J.S.1    Heuman, D.M.2    Wade, J.B.3    Gibson, D.P.4    Saeian, K.5    Wegelin, J.A.6
  • 107
    • 79960714764 scopus 로고    scopus 로고
    • Characterization of fecal microbial communities in patients with liver cirrhosis
    • Chen Y., Yang F., Lu H., Wang B., Lei D., Wang Y., et al. Characterization of fecal microbial communities in patients with liver cirrhosis. Hepatology 2011, 54:562-572.
    • (2011) Hepatology , vol.54 , pp. 562-572
    • Chen, Y.1    Yang, F.2    Lu, H.3    Wang, B.4    Lei, D.5    Wang, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.