메뉴 건너뛰기




Volumn 147, Issue 3, 2014, Pages

Roles for chemokines in liver disease

Author keywords

HCV; Immune Regulation; Inflammatory Response; NASH

Indexed keywords

CCL1 CHEMOKINE; CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR5; CHEMOKINE RECEPTOR CXCR7; CXCL1 CHEMOKINE; CXCL11 CHEMOKINE; CXCL13 CHEMOKINE; CXCL16 CHEMOKINE; CXCL2 CHEMOKINE; CXCL9 CHEMOKINE; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; FRACTALKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE CHEMOTACTIC PROTEIN 2; INTERLEUKIN 8; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 4; RANTES; SECONDARY LYMPHOID TISSUE CHEMOKINE; STROMAL CELL DERIVED FACTOR 1; THYMUS AND ACTIVATION REGULATED CHEMOKINE;

EID: 84906535982     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2014.06.043     Document Type: Review
Times cited : (653)

References (170)
  • 1
    • 81155123815 scopus 로고    scopus 로고
    • Modification of chemokine pathways and immune cell infiltration as a novel therapeutic approach in liver inflammation and fibrosis
    • H.W. Zimmermann, and F. Tacke Modification of chemokine pathways and immune cell infiltration as a novel therapeutic approach in liver inflammation and fibrosis Inflamm Allergy Drug Targets 10 2011 509 536
    • (2011) Inflamm Allergy Drug Targets , vol.10 , pp. 509-536
    • Zimmermann, H.W.1    Tacke, F.2
  • 2
    • 32144454172 scopus 로고    scopus 로고
    • Mechanisms of disease: The many roles of chemokines and chemokine receptors in inflammation
    • DOI 10.1056/NEJMra052723
    • I.F. Charo, and R.M. Ransohoff The many roles of chemokines and chemokine receptors in inflammation N Engl J Med 354 2006 610 621 (Pubitemid 43209108)
    • (2006) New England Journal of Medicine , vol.354 , Issue.6 , pp. 610-621
    • Charo, I.F.1    Ransohoff, R.M.2
  • 3
    • 0034144269 scopus 로고    scopus 로고
    • Chemokines: A new classification system and their role in immunity
    • A. Zlotnik, and O. Yoshie Chemokines: a new classification system and their role in immunity Immunity 12 2000 121 127 (Pubitemid 30398626)
    • (2000) Immunity , vol.12 , Issue.2 , pp. 121-127
    • Zlotnik, A.1    Yoshie, O.2
  • 4
    • 0035063938 scopus 로고    scopus 로고
    • Chemokine signaling and functional responses: The role of receptor dimerization and TK pathway activation
    • DOI 10.1146/annurev.immunol.19.1.397
    • M. Mellado, J.M. Rodriguez-Frade, and S. Manes et al. Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation Annu Rev Immunol 19 2001 397 421 (Pubitemid 32368041)
    • (2001) Annual Review of Immunology , vol.19 , pp. 397-421
    • Mellado, M.1    Rodriguez-Frade, J.M.2    Manes, S.3    Martinez, A.C.4
  • 5
    • 77952566640 scopus 로고    scopus 로고
    • The role of chemokines in the recruitment of lymphocytes to the liver
    • Y.H. Oo, S. Shetty, and D.H. Adams The role of chemokines in the recruitment of lymphocytes to the liver Dig Dis 28 2010 31 44
    • (2010) Dig Dis , vol.28 , pp. 31-44
    • Oo, Y.H.1    Shetty, S.2    Adams, D.H.3
  • 7
    • 77954983463 scopus 로고    scopus 로고
    • Chemokines in liver inflammation and fibrosis
    • H.E. Wasmuth, F. Tacke, and C. Trautwein Chemokines in liver inflammation and fibrosis Semin Liver Dis 30 2010 215 225
    • (2010) Semin Liver Dis , vol.30 , pp. 215-225
    • Wasmuth, H.E.1    Tacke, F.2    Trautwein, C.3
  • 8
    • 79955476625 scopus 로고    scopus 로고
    • Overcoming hurdles in developing successful drugs targeting chemokine receptors
    • T.J. Schall, and A.E. Proudfoot Overcoming hurdles in developing successful drugs targeting chemokine receptors Nat Rev Immunol 11 2011 355 363
    • (2011) Nat Rev Immunol , vol.11 , pp. 355-363
    • Schall, T.J.1    Proudfoot, A.E.2
  • 9
    • 84857538593 scopus 로고    scopus 로고
    • Disease tolerance as a defense strategy
    • R. Medzhitov, D.S. Schneider, and M.P. Soares Disease tolerance as a defense strategy Science 335 2012 936 941
    • (2012) Science , vol.335 , pp. 936-941
    • Medzhitov, R.1    Schneider, D.S.2    Soares, M.P.3
  • 10
    • 84866148172 scopus 로고    scopus 로고
    • Innate immune cells in liver inflammation
    • E. Liaskou, D.V. Wilson, and Y.H. Oo Innate immune cells in liver inflammation Mediators Inflamm 2012 2012 949157
    • (2012) Mediators Inflamm , vol.2012 , pp. 949157
    • Liaskou, E.1    Wilson, D.V.2    Oo, Y.H.3
  • 11
    • 0036242256 scopus 로고    scopus 로고
    • Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse
    • DOI 10.1053/jhep.2002.33162
    • D.M. Dambach, L.M. Watson, and K.R. Gray et al. Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse Hepatology 35 2002 1093 1103 (Pubitemid 34454006)
    • (2002) Hepatology , vol.35 , Issue.5 , pp. 1093-1103
    • Dambach, D.M.1    Watson, L.M.2    Gray, K.R.3    Durham, S.K.4    Laskin, D.L.5
  • 13
    • 67651174837 scopus 로고    scopus 로고
    • Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis
    • K.R. Karlmark, R. Weiskirchen, and H.W. Zimmermann et al. Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis Hepatology 50 2009 261 274
    • (2009) Hepatology , vol.50 , pp. 261-274
    • Karlmark, K.R.1    Weiskirchen, R.2    Zimmermann, H.W.3
  • 14
    • 33645902493 scopus 로고    scopus 로고
    • Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
    • N.V. Serbina, and E.G. Pamer Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2 Nat Immunol 7 2006 311 317
    • (2006) Nat Immunol , vol.7 , pp. 311-317
    • Serbina, N.V.1    Pamer, E.G.2
  • 15
    • 84857444883 scopus 로고    scopus 로고
    • Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice
    • F. Heymann, L. Hammerich, and D. Storch et al. Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice Hepatology 55 2012 898 909
    • (2012) Hepatology , vol.55 , pp. 898-909
    • Heymann, F.1    Hammerich, L.2    Storch, D.3
  • 16
    • 84856170838 scopus 로고    scopus 로고
    • CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis
    • N. Nakamoto, H. Ebinuma, and T. Kanai et al. CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis Gastroenterology 142 2012 366 376
    • (2012) Gastroenterology , vol.142 , pp. 366-376
    • Nakamoto, N.1    Ebinuma, H.2    Kanai, T.3
  • 17
    • 78049492110 scopus 로고    scopus 로고
    • The fractalkine receptor CX(3)CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes
    • K.R. Karlmark, H.W. Zimmermann, and C. Roderburg et al. The fractalkine receptor CX(3)CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes Hepatology 52 2010 1769 1782
    • (2010) Hepatology , vol.52 , pp. 1769-1782
    • Karlmark, K.R.1    Zimmermann, H.W.2    Roderburg, C.3
  • 18
    • 33644544110 scopus 로고    scopus 로고
    • The liver as an immunological organ
    • V. Racanelli, and B. Rehermann The liver as an immunological organ Hepatology 43 2006 S54 S62
    • (2006) Hepatology , vol.43
    • Racanelli, V.1    Rehermann, B.2
  • 19
    • 0036486763 scopus 로고    scopus 로고
    • Role of chemokines in the biology of natural killer cells
    • M.J. Robertson Role of chemokines in the biology of natural killer cells J Leukoc Biol 71 2002 173 183
    • (2002) J Leukoc Biol , vol.71 , pp. 173-183
    • Robertson, M.J.1
  • 20
    • 34447338611 scopus 로고    scopus 로고
    • CCR5 deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis
    • DOI 10.2353/ajpath.2007.060690
    • M.N. Ajuebor, Z. Wondimu, and C.M. Hogaboam et al. CCR5 deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis Am J Pathol 170 2007 1975 1988 (Pubitemid 47339271)
    • (2007) American Journal of Pathology , vol.170 , Issue.6 , pp. 1975-1988
    • Ajuebor, M.N.1    Wondimu, Z.2    Hogaboam, C.M.3    Le, T.4    Proudfoot, A.E.I.5    Swain, M.G.6
  • 21
    • 19344371631 scopus 로고    scopus 로고
    • Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids
    • F. Geissmann, T.O. Cameron, and S. Sidobre et al. Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids PLoS Biol 3 2005 e113
    • (2005) PLoS Biol , vol.3 , pp. 113
    • Geissmann, F.1    Cameron, T.O.2    Sidobre, S.3
  • 22
    • 84877794003 scopus 로고    scopus 로고
    • Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis
    • A. Wehr, C. Baeck, and F. Heymann et al. Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis J Immunol 190 2013 5226 5236
    • (2013) J Immunol , vol.190 , pp. 5226-5236
    • Wehr, A.1    Baeck, C.2    Heymann, F.3
  • 23
    • 84867577705 scopus 로고    scopus 로고
    • CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver
    • Y.H. Oo, V. Banz, and D. Kavanagh et al. CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver J Hepatol 57 2012 1044 1051
    • (2012) J Hepatol , vol.57 , pp. 1044-1051
    • Oo, Y.H.1    Banz, V.2    Kavanagh, D.3
  • 24
    • 84893650001 scopus 로고    scopus 로고
    • Chemokine receptor CCR6-dependent accumulation of gammadelta T cells in injured liver restricts hepatic inflammation and fibrosis
    • L. Hammerich, J.M. Bangen, and O. Govaere et al. Chemokine receptor CCR6-dependent accumulation of gammadelta T cells in injured liver restricts hepatic inflammation and fibrosis Hepatology 59 2014 630 642
    • (2014) Hepatology , vol.59 , pp. 630-642
    • Hammerich, L.1    Bangen, J.M.2    Govaere, O.3
  • 25
    • 52649134580 scopus 로고    scopus 로고
    • GammadeltaT cells initiate acute inflammation and injury in adenovirus-infected liver via cytokine-chemokine cross talk
    • M.N. Ajuebor, Y. Jin, and G.L. Gremillion et al. GammadeltaT cells initiate acute inflammation and injury in adenovirus-infected liver via cytokine-chemokine cross talk J Virol 82 2008 9564 9576
    • (2008) J Virol , vol.82 , pp. 9564-9576
    • Ajuebor, M.N.1    Jin, Y.2    Gremillion, G.L.3
  • 26
    • 84880276248 scopus 로고    scopus 로고
    • Pathogenesis of chronic viral hepatitis: Differential roles of T cells and NK cells
    • B. Rehermann Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells Nat Med 19 2013 859 868
    • (2013) Nat Med , vol.19 , pp. 859-868
    • Rehermann, B.1
  • 27
    • 79251575277 scopus 로고    scopus 로고
    • Role of IL-17 and Th17 cells in liver diseases
    • L. Hammerich, F. Heymann, and F. Tacke Role of IL-17 and Th17 cells in liver diseases Clin Dev Immunol 2011 2011 345803
    • (2011) Clin Dev Immunol , vol.2011 , pp. 345803
    • Hammerich, L.1    Heymann, F.2    Tacke, F.3
  • 28
    • 58649089811 scopus 로고    scopus 로고
    • Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver
    • A.P. Holt, E.L. Haughton, and P.F. Lalor et al. Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver Gastroenterology 136 2009 705 714
    • (2009) Gastroenterology , vol.136 , pp. 705-714
    • Holt, A.P.1    Haughton, E.L.2    Lalor, P.F.3
  • 29
    • 84891754161 scopus 로고    scopus 로고
    • The role of chemokines in acute and chronic hepatitis C infection
    • S. Fahey, E. Dempsey, and A. Long The role of chemokines in acute and chronic hepatitis C infection Cell Mol Immunol 11 2014 25 40
    • (2014) Cell Mol Immunol , vol.11 , pp. 25-40
    • Fahey, S.1    Dempsey, E.2    Long, A.3
  • 30
    • 84896334634 scopus 로고    scopus 로고
    • Positioning of leukocyte subsets in the portal and lobular compartments of hepatitis C virus-infected liver correlates with local chemokine expression
    • N. Nguyen, C. de Esch, and B. Cameron et al. Positioning of leukocyte subsets in the portal and lobular compartments of hepatitis C virus-infected liver correlates with local chemokine expression J Gastroenterol Hepatol 29 2014 860 869
    • (2014) J Gastroenterol Hepatol , vol.29 , pp. 860-869
    • Nguyen, N.1    De Esch, C.2    Cameron, B.3
  • 33
    • 80755130163 scopus 로고    scopus 로고
    • CCL5: A double-edged sword in host defense against the hepatitis C virus
    • A. Katsounas, J.F. Schlaak, and R.A. Lempicki CCL5: a double-edged sword in host defense against the hepatitis C virus Int Rev Immunol 30 2011 366 378
    • (2011) Int Rev Immunol , vol.30 , pp. 366-378
    • Katsounas, A.1    Schlaak, J.F.2    Lempicki, R.A.3
  • 34
    • 77950975669 scopus 로고    scopus 로고
    • The role of CCR5 in HCV infection
    • M. Coenen, and J. Nattermann The role of CCR5 in HCV infection Eur J Med Res 15 2010 97 101
    • (2010) Eur J Med Res , vol.15 , pp. 97-101
    • Coenen, M.1    Nattermann, J.2
  • 36
    • 84155175629 scopus 로고    scopus 로고
    • Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression
    • J. Jiao, D. Sastre, and M.I. Fiel et al. Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression Hepatology 55 2012 244 255
    • (2012) Hepatology , vol.55 , pp. 244-255
    • Jiao, J.1    Sastre, D.2    Fiel, M.I.3
  • 37
    • 0036938925 scopus 로고    scopus 로고
    • Expression of a full-length hepatitis C virus cDNA up-regulates the expression of CC chemokines MCP-1 and RANTES
    • DOI 10.1006/viro.2002.1617
    • H.M. Soo, A. Garzino-Demo, and W. Hong et al. Expression of a full-length hepatitis C virus cDNA up-regulates the expression of CC chemokines MCP-1 and RANTES Virology 303 2002 253 277 (Pubitemid 36069190)
    • (2002) Virology , vol.303 , Issue.2 , pp. 253-277
    • Soo, H.M.1    Garzino-Demo, A.2    Hong, W.3    Tan, Y.H.4    Tan, Y.J.5    Goh, P.-Y.6    Lim, S.G.7    Lim, S.P.8
  • 38
    • 84860389820 scopus 로고    scopus 로고
    • Induction of CXCR3- and CCR5-associated chemokines during acute hepatitis C virus infection
    • M. Zeremski, G. Hooker, and M.A. Shu et al. Induction of CXCR3- and CCR5-associated chemokines during acute hepatitis C virus infection J Hepatol 55 2011 545 553
    • (2011) J Hepatol , vol.55 , pp. 545-553
    • Zeremski, M.1    Hooker, G.2    Shu, M.A.3
  • 39
    • 80051521537 scopus 로고    scopus 로고
    • Delayed induction, not impaired recruitment, of specific CD8(+) T cells causes the late onset of acute hepatitis C
    • 695 e1
    • E.C. Shin, S.H. Park, and M. Demino et al. Delayed induction, not impaired recruitment, of specific CD8(+) T cells causes the late onset of acute hepatitis C Gastroenterology 141 2011 686 695 695 e1
    • (2011) Gastroenterology , vol.141 , pp. 686-695
    • Shin, E.C.1    Park, S.H.2    Demino, M.3
  • 40
    • 79951680384 scopus 로고    scopus 로고
    • Hepatitis C virus induces the expression of CCL17 and CCL22 chemokines that attract regulatory T cells to the site of infection
    • J.I. Riezu-Boj, E. Larrea, and R. Aldabe et al. Hepatitis C virus induces the expression of CCL17 and CCL22 chemokines that attract regulatory T cells to the site of infection J Hepatol 54 2011 422 431
    • (2011) J Hepatol , vol.54 , pp. 422-431
    • Riezu-Boj, J.I.1    Larrea, E.2    Aldabe, R.3
  • 41
    • 77951910350 scopus 로고    scopus 로고
    • Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver
    • Y.H. Oo, C.J. Weston, and P.F. Lalor et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver J Immunol 184 2010 2886 2898
    • (2010) J Immunol , vol.184 , pp. 2886-2898
    • Oo, Y.H.1    Weston, C.J.2    Lalor, P.F.3
  • 42
    • 84873287621 scopus 로고    scopus 로고
    • Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes
    • H. Sahin, E. Borkham-Kamphorst, and N.T. do O et al. Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes Hepatology 57 2013 797 805
    • (2013) Hepatology , vol.57 , pp. 797-805
    • Sahin, H.1    Borkham-Kamphorst, E.2    Do, O.N.T.3
  • 43
    • 72849128563 scopus 로고    scopus 로고
    • Peripheral CXCR3-associated chemokines as biomarkers of fibrosis in chronic hepatitis C virus infection
    • M. Zeremski, R. Dimova, and Q. Brown et al. Peripheral CXCR3-associated chemokines as biomarkers of fibrosis in chronic hepatitis C virus infection J Infect Dis 200 2009 1774 1780
    • (2009) J Infect Dis , vol.200 , pp. 1774-1780
    • Zeremski, M.1    Dimova, R.2    Brown, Q.3
  • 44
    • 56149085947 scopus 로고    scopus 로고
    • Intrahepatic levels of CXCR3-associated chemokines correlate with liver inflammation and fibrosis in chronic hepatitis C
    • M. Zeremski, L.M. Petrovic, and L. Chiriboga et al. Intrahepatic levels of CXCR3-associated chemokines correlate with liver inflammation and fibrosis in chronic hepatitis C Hepatology 48 2008 1440 1450
    • (2008) Hepatology , vol.48 , pp. 1440-1450
    • Zeremski, M.1    Petrovic, L.M.2    Chiriboga, L.3
  • 46
    • 79958073303 scopus 로고    scopus 로고
    • Serum chemokine receptor CXCR3 ligands are associated with progression, organ dysfunction and complications of chronic liver diseases
    • F. Tacke, H.W. Zimmermann, and M.L. Berres et al. Serum chemokine receptor CXCR3 ligands are associated with progression, organ dysfunction and complications of chronic liver diseases Liver Int 31 2011 840 849
    • (2011) Liver Int , vol.31 , pp. 840-849
    • Tacke, F.1    Zimmermann, H.W.2    Berres, M.L.3
  • 47
    • 80052247715 scopus 로고    scopus 로고
    • CXCL9 and CXCL10 chemokines as predictors of liver fibrosis in a cohort of primarily African-American injection drug users with chronic hepatitis C
    • M. Zeremski, R. Dimova, and J. Astemborski et al. CXCL9 and CXCL10 chemokines as predictors of liver fibrosis in a cohort of primarily African-American injection drug users with chronic hepatitis C J Infect Dis 204 2011 832 836
    • (2011) J Infect Dis , vol.204 , pp. 832-836
    • Zeremski, M.1    Dimova, R.2    Astemborski, J.3
  • 48
    • 79251527204 scopus 로고    scopus 로고
    • Serum chemokine CXC ligand 10 (CXCL10) predicts fibrosis progression after liver transplantation for hepatitis C infection
    • M.L. Berres, C. Trautwein, and M. Schmeding et al. Serum chemokine CXC ligand 10 (CXCL10) predicts fibrosis progression after liver transplantation for hepatitis C infection Hepatology 53 2011 596 603
    • (2011) Hepatology , vol.53 , pp. 596-603
    • Berres, M.L.1    Trautwein, C.2    Schmeding, M.3
  • 49
    • 78650962504 scopus 로고    scopus 로고
    • Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV
    • A. Casrouge, J. Decalf, and M. Ahloulay et al. Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV J Clin Invest 121 2011 308 317
    • (2011) J Clin Invest , vol.121 , pp. 308-317
    • Casrouge, A.1    Decalf, J.2    Ahloulay, M.3
  • 50
    • 84863615340 scopus 로고    scopus 로고
    • The CXCR3(+)CD56Bright phenotype characterizes a distinct NK cell subset with anti-fibrotic potential that shows dys-regulated activity in hepatitis C
    • M. Eisenhardt, A. Glassner, and B. Kramer et al. The CXCR3(+)CD56Bright phenotype characterizes a distinct NK cell subset with anti-fibrotic potential that shows dys-regulated activity in hepatitis C PLoS One 7 2012 e38846
    • (2012) PLoS One , vol.7 , pp. 38846
    • Eisenhardt, M.1    Glassner, A.2    Kramer, B.3
  • 51
    • 78449275107 scopus 로고    scopus 로고
    • Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses
    • S. Paust, H.S. Gill, B.Z. Wang, and M.P. Flynn et al. Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses Nat Immunol 11 2010 1127 1135
    • (2010) Nat Immunol , vol.11 , pp. 1127-1135
    • Paust, S.1    Gill, H.S.2    Wang, B.Z.3    Flynn, M.P.4
  • 52
    • 0035905411 scopus 로고    scopus 로고
    • Blocking chemokine responsive to γ-2/interferon (IFN)-γ inducible protein and monokine induced by IFN-γ activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes
    • DOI 10.1084/jem.194.12.1755
    • K. Kakimi, T.E. Lane, and S. Wieland et al. Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes J Exp Med 194 2001 1755 1766 (Pubitemid 34028655)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.12 , pp. 1755-1766
    • Kakimi, K.1    Lane, T.E.2    Wieland, S.3    Asensio, V.C.4    Campbell, I.L.5    Chisari, F.V.6    Guidotti, L.G.7
  • 53
    • 84895737359 scopus 로고    scopus 로고
    • Cytokine and chemokine responses in the acute phase of hepatitis B virus replication in naive and previously vaccinated blood and plasma donors
    • S.M. Keating, J.D. Heitman, and S. Wu et al. Cytokine and chemokine responses in the acute phase of hepatitis B virus replication in naive and previously vaccinated blood and plasma donors J Infect Dis 209 2014 845 854
    • (2014) J Infect Dis , vol.209 , pp. 845-854
    • Keating, S.M.1    Heitman, J.D.2    Wu, S.3
  • 55
    • 77249098281 scopus 로고    scopus 로고
    • A longitudinal analysis of innate and adaptive immune profile during hepatic flares in chronic hepatitis B
    • A.T. Tan, S. Koh, and W. Goh et al. A longitudinal analysis of innate and adaptive immune profile during hepatic flares in chronic hepatitis B J Hepatol 52 2010 330 339
    • (2010) J Hepatol , vol.52 , pp. 330-339
    • Tan, A.T.1    Koh, S.2    Goh, W.3
  • 56
    • 77951222181 scopus 로고    scopus 로고
    • Hepatitis B virus protein X-induced expression of the CXC chemokine IP-10 is mediated through activation of NF-kappaB and increases migration of leukocytes
    • Y. Zhou, S. Wang, and J.W. Ma et al. Hepatitis B virus protein X-induced expression of the CXC chemokine IP-10 is mediated through activation of NF-kappaB and increases migration of leukocytes J Biol Chem 285 2010 12159 12168
    • (2010) J Biol Chem , vol.285 , pp. 12159-12168
    • Zhou, Y.1    Wang, S.2    Ma, J.W.3
  • 57
    • 80052957789 scopus 로고    scopus 로고
    • Hepatitis B surface antigen (HBsAg) decrease and serum interferon-inducible protein-10 levels as predictive markers for HBsAg loss during treatment with nucleoside/nucleotide analogues
    • J. Jaroszewicz, H. Ho, and A. Markova et al. Hepatitis B surface antigen (HBsAg) decrease and serum interferon-inducible protein-10 levels as predictive markers for HBsAg loss during treatment with nucleoside/nucleotide analogues Antivir Ther 16 2011 915 924
    • (2011) Antivir Ther , vol.16 , pp. 915-924
    • Jaroszewicz, J.1    Ho, H.2    Markova, A.3
  • 58
    • 84876284069 scopus 로고    scopus 로고
    • Serum levels of interferon-gamma-inducible protein 10 and response to peginterferon therapy in HBeAg-positive chronic hepatitis B
    • M.J. Sonneveld, P. Arends, and A. Boonstra et al. Serum levels of interferon-gamma-inducible protein 10 and response to peginterferon therapy in HBeAg-positive chronic hepatitis B J Hepatol 58 2013 898 903
    • (2013) J Hepatol , vol.58 , pp. 898-903
    • Sonneveld, M.J.1    Arends, P.2    Boonstra, A.3
  • 60
    • 79958822254 scopus 로고    scopus 로고
    • Enhanced B-cell differentiation and reduced proliferative capacity in chronic hepatitis C and chronic hepatitis B virus infections
    • B. Oliviero, A. Cerino, and S. Varchetta et al. Enhanced B-cell differentiation and reduced proliferative capacity in chronic hepatitis C and chronic hepatitis B virus infections J Hepatol 55 2011 53 60
    • (2011) J Hepatol , vol.55 , pp. 53-60
    • Oliviero, B.1    Cerino, A.2    Varchetta, S.3
  • 61
    • 84884979909 scopus 로고    scopus 로고
    • Circulating chemokine (C-X-C Motif) receptor 5(+) CD4(+) T cells benefit hepatitis B e antigen seroconversion through IL-21 in patients with chronic hepatitis B virus infection
    • Y. Li, S. Ma, and L. Tang et al. Circulating chemokine (C-X-C Motif) receptor 5(+) CD4(+) T cells benefit hepatitis B e antigen seroconversion through IL-21 in patients with chronic hepatitis B virus infection Hepatology 58 2013 1277 1286
    • (2013) Hepatology , vol.58 , pp. 1277-1286
    • Li, Y.1    Ma, S.2    Tang, L.3
  • 62
    • 84864118287 scopus 로고    scopus 로고
    • Immunological complications of obesity
    • T.D. Kanneganti, and V.D. Dixit Immunological complications of obesity Nat Immunol 13 2012 707 712
    • (2012) Nat Immunol , vol.13 , pp. 707-712
    • Kanneganti, T.D.1    Dixit, V.D.2
  • 64
    • 33745216724 scopus 로고    scopus 로고
    • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
    • H. Kanda, S. Tateya, and Y. Tamori et al. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity J Clin Invest 116 2006 1494 1505
    • (2006) J Clin Invest , vol.116 , pp. 1494-1505
    • Kanda, H.1    Tateya, S.2    Tamori, Y.3
  • 65
    • 34548434020 scopus 로고    scopus 로고
    • Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue
    • DOI 10.2337/db07-0425
    • K.E. Inouye, H. Shi, and J.K. Howard et al. Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue Diabetes 56 2007 2242 2250 (Pubitemid 47358231)
    • (2007) Diabetes , vol.56 , Issue.9 , pp. 2242-2250
    • Inouye, K.E.1    Shi, H.2    Howard, J.K.3    Daly, C.H.4    Lord, G.M.5    Rollins, B.J.6    Flier, J.S.7
  • 66
    • 48449102722 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein deficiency fails to restrain macrophage infiltration into adipose tissue [corrected]
    • E.A. Kirk, Z.K. Sagawa, and T.O. McDonald et al. Monocyte chemoattractant protein deficiency fails to restrain macrophage infiltration into adipose tissue [corrected] Diabetes 57 2008 1254 1261
    • (2008) Diabetes , vol.57 , pp. 1254-1261
    • Kirk, E.A.1    Sagawa, Z.K.2    McDonald, T.O.3
  • 67
    • 77149154977 scopus 로고    scopus 로고
    • An increase in the circulating concentration of monocyte chemoattractant protein-1 elicits systemic insulin resistance irrespective of adipose tissue inflammation in mice
    • S. Tateya, Y. Tamori, and T. Kawaguchi et al. An increase in the circulating concentration of monocyte chemoattractant protein-1 elicits systemic insulin resistance irrespective of adipose tissue inflammation in mice Endocrinology 151 2010 971 979
    • (2010) Endocrinology , vol.151 , pp. 971-979
    • Tateya, S.1    Tamori, Y.2    Kawaguchi, T.3
  • 70
    • 77951160365 scopus 로고    scopus 로고
    • C-C chemokine receptor 2 inhibitor improves diet-induced development of insulin resistance and hepatic steatosis in mice
    • Y. Tamura, M. Sugimoto, and T. Murayama et al. C-C chemokine receptor 2 inhibitor improves diet-induced development of insulin resistance and hepatic steatosis in mice J Atheroscler Thromb 17 2010 219 228
    • (2010) J Atheroscler Thromb , vol.17 , pp. 219-228
    • Tamura, Y.1    Sugimoto, M.2    Murayama, T.3
  • 71
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • DOI 10.1172/JCI29881
    • C.N. Lumeng, J.L. Bodzin, and A.R. Saltiel Obesity induces a phenotypic switch in adipose tissue macrophage polarization J Clin Invest 117 2007 175 184 (Pubitemid 46048464)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.1 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 72
    • 84863223829 scopus 로고    scopus 로고
    • CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 status
    • H. Kitade, K. Sawamoto, and M. Nagashimada et al. CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 status Diabetes 61 2012 1680 1690
    • (2012) Diabetes , vol.61 , pp. 1680-1690
    • Kitade, H.1    Sawamoto, K.2    Nagashimada, M.3
  • 73
    • 76049100165 scopus 로고    scopus 로고
    • The role of chemokines in recruitment of immune cells to the artery wall and adipose tissue
    • B.K. Surmi, and A.H. Hasty The role of chemokines in recruitment of immune cells to the artery wall and adipose tissue Vascul Pharmacol 52 2010 27 36
    • (2010) Vascul Pharmacol , vol.52 , pp. 27-36
    • Surmi, B.K.1    Hasty, A.H.2
  • 74
    • 49249116067 scopus 로고    scopus 로고
    • CC chemokine and CC chemokine receptor profiles in visceral and subcutaneous adipose tissue are altered in human obesity
    • J. Huber, F.W. Kiefer, and M. Zeyda et al. CC chemokine and CC chemokine receptor profiles in visceral and subcutaneous adipose tissue are altered in human obesity J Clin Endocrinol Metab 93 2008 3215 3221
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3215-3221
    • Huber, J.1    Kiefer, F.W.2    Zeyda, M.3
  • 75
    • 84874596950 scopus 로고    scopus 로고
    • Roles of chemokine ligand-2 (CXCL2) and neutrophils in influencing endothelial cell function and inflammation of human adipose tissue
    • C. Rouault, V. Pellegrinelli, and R. Schilch et al. Roles of chemokine ligand-2 (CXCL2) and neutrophils in influencing endothelial cell function and inflammation of human adipose tissue Endocrinology 154 2013 1069 1079
    • (2013) Endocrinology , vol.154 , pp. 1069-1079
    • Rouault, C.1    Pellegrinelli, V.2    Schilch, R.3
  • 76
    • 70349563430 scopus 로고    scopus 로고
    • Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators
    • C. Duffaut, A. Zakaroff-Girard, and V. Bourlier et al. Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators Arterioscler Thromb Vasc Biol 29 2009 1608 1614
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1608-1614
    • Duffaut, C.1    Zakaroff-Girard, A.2    Bourlier, V.3
  • 77
    • 77449117735 scopus 로고    scopus 로고
    • Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance
    • W. Huang, A. Metlakunta, and N. Dedousis et al. Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance Diabetes 59 2010 347 357
    • (2010) Diabetes , vol.59 , pp. 347-357
    • Huang, W.1    Metlakunta, A.2    Dedousis, N.3
  • 78
    • 82655181355 scopus 로고    scopus 로고
    • Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet
    • N. Lanthier, O. Molendi-Coste, and P.D. Cani et al. Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet FASEB J 25 2011 4301 4311
    • (2011) FASEB J , vol.25 , pp. 4301-4311
    • Lanthier, N.1    Molendi-Coste, O.2    Cani, P.D.3
  • 79
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: In vivo veritas
    • A. Sica, and A. Mantovani Macrophage plasticity and polarization: in vivo veritas J Clin Invest 122 2012 787 795
    • (2012) J Clin Invest , vol.122 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 80
    • 77953891627 scopus 로고    scopus 로고
    • Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice
    • K. Miura, Y. Kodama, and S. Inokuchi et al. Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice Gastroenterology 139 2010 323 334.e7
    • (2010) Gastroenterology , vol.139
    • Miura, K.1    Kodama, Y.2    Inokuchi, S.3
  • 81
    • 75449101395 scopus 로고    scopus 로고
    • Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity
    • R. Stienstra, F. Saudale, and C. Duval et al. Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity Hepatology 51 2010 511 522
    • (2010) Hepatology , vol.51 , pp. 511-522
    • Stienstra, R.1    Saudale, F.2    Duval, C.3
  • 82
    • 84868202269 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 (MCP-1) deficiency enhances alternatively activated M2 macrophages and ameliorates insulin resistance and fatty liver in lipoatrophic diabetic A-ZIP transgenic mice
    • Y. Nio, T. Yamauchi, and M. Iwabu et al. Monocyte chemoattractant protein-1 (MCP-1) deficiency enhances alternatively activated M2 macrophages and ameliorates insulin resistance and fatty liver in lipoatrophic diabetic A-ZIP transgenic mice Diabetologia 55 2012 3350 3358
    • (2012) Diabetologia , vol.55 , pp. 3350-3358
    • Nio, Y.1    Yamauchi, T.2    Iwabu, M.3
  • 83
    • 64149125118 scopus 로고    scopus 로고
    • Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy
    • S.J. Yang, H.B. IglayReger, and H.C. Kadouh et al. Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy Diabetologia 52 2009 972 981
    • (2009) Diabetologia , vol.52 , pp. 972-981
    • Yang, S.J.1    Iglayreger, H.B.2    Kadouh, H.C.3
  • 84
    • 84856533216 scopus 로고    scopus 로고
    • Increased macrophage migration into adipose tissue in obese mice
    • D.Y. Oh, H. Morinaga, and S. Talukdar et al. Increased macrophage migration into adipose tissue in obese mice Diabetes 61 2012 346 354
    • (2012) Diabetes , vol.61 , pp. 346-354
    • Oh, D.Y.1    Morinaga, H.2    Talukdar, S.3
  • 85
    • 33646161443 scopus 로고    scopus 로고
    • Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2
    • J.W. Haukeland, J.K. Damas, and Z. Konopski et al. Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2 J Hepatol 44 2006 1167 1174
    • (2006) J Hepatol , vol.44 , pp. 1167-1174
    • Haukeland, J.W.1    Damas, J.K.2    Konopski, Z.3
  • 86
    • 77951146612 scopus 로고    scopus 로고
    • C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis
    • A.E. Obstfeld, E. Sugaru, and M. Thearle et al. C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis Diabetes 59 2010 916 925
    • (2010) Diabetes , vol.59 , pp. 916-925
    • Obstfeld, A.E.1    Sugaru, E.2    Thearle, M.3
  • 87
    • 84861872575 scopus 로고    scopus 로고
    • Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2
    • K. Miura, L. Yang, and N. van Rooijen et al. Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2 Am J Physiol Gastrointest Liver Physiol 302 2012 G1310 G1321
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.302
    • Miura, K.1    Yang, L.2    Van Rooijen, N.3
  • 88
    • 84857055199 scopus 로고    scopus 로고
    • Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury
    • C. Baeck, A. Wehr, and K.R. Karlmark et al. Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury Gut 61 2012 416 426
    • (2012) Gut , vol.61 , pp. 416-426
    • Baeck, C.1    Wehr, A.2    Karlmark, K.R.3
  • 89
    • 84862669638 scopus 로고    scopus 로고
    • Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis
    • A. Leroux, G. Ferrere, and V. Godie et al. Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis J Hepatol 57 2012 141 149
    • (2012) J Hepatol , vol.57 , pp. 141-149
    • Leroux, A.1    Ferrere, G.2    Godie, V.3
  • 90
    • 51349151813 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes
    • S. Clement, C. Juge-Aubry, and A. Sgroi et al. Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes Hepatology 48 2008 799 807
    • (2008) Hepatology , vol.48 , pp. 799-807
    • Clement, S.1    Juge-Aubry, C.2    Sgroi, A.3
  • 91
    • 78649681353 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient diet
    • K.M. Kassel, G.L. Guo, and O. Tawfik et al. Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient diet Lab Invest 90 2010 1794 1804
    • (2010) Lab Invest , vol.90 , pp. 1794-1804
    • Kassel, K.M.1    Guo, G.L.2    Tawfik, O.3
  • 92
    • 84864017250 scopus 로고    scopus 로고
    • Lack of CC chemokine ligand 2 differentially affects inflammation and fibrosis according to the genetic background in a murine model of steatohepatitis
    • S. Galastri, E. Zamara, and S. Milani et al. Lack of CC chemokine ligand 2 differentially affects inflammation and fibrosis according to the genetic background in a murine model of steatohepatitis Clin Sci (Lond) 123 2012 459 471
    • (2012) Clin Sci (Lond) , vol.123 , pp. 459-471
    • Galastri, S.1    Zamara, E.2    Milani, S.3
  • 93
    • 84878752311 scopus 로고    scopus 로고
    • CCR2 and CD44 promote inflammatory cell recruitment during fatty liver formation in a lithogenic diet fed mouse model
    • C.E. Egan, E.K. Daugherity, and A.B. Rogers et al. CCR2 and CD44 promote inflammatory cell recruitment during fatty liver formation in a lithogenic diet fed mouse model PLoS One 8 2013 e65247
    • (2013) PLoS One , vol.8 , pp. 65247
    • Egan, C.E.1    Daugherity, E.K.2    Rogers, A.B.3
  • 94
    • 77956093740 scopus 로고    scopus 로고
    • Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation
    • G. Kirovski, E. Gabele, and C. Dorn et al. Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation Int J Clin Exp Pathol 3 2010 675 680
    • (2010) Int J Clin Exp Pathol , vol.3 , pp. 675-680
    • Kirovski, G.1    Gabele, E.2    Dorn, C.3
  • 95
    • 42949095985 scopus 로고    scopus 로고
    • Obesity-induced lymphocyte hyperresponsiveness to chemokines: A new mechanism of Fatty liver inflammation in obese mice
    • A.E. Bigorgne, L. Bouchet-Delbos, and S. Naveau et al. Obesity-induced lymphocyte hyperresponsiveness to chemokines: a new mechanism of Fatty liver inflammation in obese mice Gastroenterology 134 2008 1459 1469
    • (2008) Gastroenterology , vol.134 , pp. 1459-1469
    • Bigorgne, A.E.1    Bouchet-Delbos, L.2    Naveau, S.3
  • 96
    • 0027294661 scopus 로고
    • Circulating and tissue levels of the neutrophil chemotaxin interleukin-8 are elevated in severe acute alcoholic hepatitis, and tissue levels correlate with neutrophil infiltration
    • DOI 10.1016/0270-9139(93)90504-G
    • N. Sheron, G. Bird, and J. Koskinas et al. Circulating and tissue levels of the neutrophil chemotaxin interleukin-8 are elevated in severe acute alcoholic hepatitis, and tissue levels correlate with neutrophil infiltration Hepatology 18 1993 41 46 (Pubitemid 23193615)
    • (1993) Hepatology , vol.18 , Issue.1 , pp. 41-46
    • Sheron, N.1    Bird, G.2    Koskinas, J.3    Portmann, B.4    Ceska, M.5    Lindley, I.6    Williams, R.7
  • 97
    • 0028883637 scopus 로고
    • Rat hepatocytes and Kupffer cells interact to produce interleukin-8 (CINC) in the setting of ethanol
    • J.J. Maher Rat hepatocytes and Kupffer cells interact to produce interleukin-8 (CINC) in the setting of ethanol Am J Physiol 269 1995 G518 G523
    • (1995) Am J Physiol , vol.269
    • Maher, J.J.1
  • 99
    • 0031685777 scopus 로고    scopus 로고
    • Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis
    • DOI 10.1002/(SICI)1096-9896(199809)186:1<82::AID-PATH151>3.0.CO;2-D
    • S.C. Afford, N.C. Fisher, and D.A. Neil et al. Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis J Pathol 186 1998 82 89 (Pubitemid 28407492)
    • (1998) Journal of Pathology , vol.186 , Issue.1 , pp. 82-89
    • Afford, S.C.1    Fisher, N.C.2    Neil, D.A.H.3    Fear, J.4    Brun, P.5    Hubscher, S.G.6    Adams, D.H.7
  • 101
    • 65249087414 scopus 로고    scopus 로고
    • Hepatic expression of CXC chemokines predicts portal hypertension and survival in patients with alcoholic hepatitis
    • M. Dominguez, R. Miquel, and J. Colmenero et al. Hepatic expression of CXC chemokines predicts portal hypertension and survival in patients with alcoholic hepatitis Gastroenterology 136 2009 1639 1650
    • (2009) Gastroenterology , vol.136 , pp. 1639-1650
    • Dominguez, M.1    Miquel, R.2    Colmenero, J.3
  • 102
    • 84892469998 scopus 로고    scopus 로고
    • CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis
    • [Epub ahead of print]
    • S. Affo, O. Morales-Ibanez, and D. Rodrigo-Torres et al. CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis Gut 2014 Jan 20 [Epub ahead of print]
    • (2014) Gut
    • Affo, S.1    Morales-Ibanez, O.2    Rodrigo-Torres, D.3
  • 103
    • 84864740260 scopus 로고    scopus 로고
    • Hepatic expression of CCL2 in alcoholic liver disease is associated with disease severity and neutrophil infiltrates
    • D. Degre, A. Lemmers, and T. Gustot et al. Hepatic expression of CCL2 in alcoholic liver disease is associated with disease severity and neutrophil infiltrates Clin Exp Immunol 169 2012 302 310
    • (2012) Clin Exp Immunol , vol.169 , pp. 302-310
    • Degre, D.1    Lemmers, A.2    Gustot, T.3
  • 104
    • 82455167937 scopus 로고    scopus 로고
    • An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: Regulation of proinflammatory cytokines and hepatic steatosis in mice
    • P. Mandrekar, A. Ambade, and A. Lim et al. An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice Hepatology 54 2011 2185 2197
    • (2011) Hepatology , vol.54 , pp. 2185-2197
    • Mandrekar, P.1    Ambade, A.2    Lim, A.3
  • 105
    • 84883218984 scopus 로고    scopus 로고
    • Cellular basis of hepatic fibrosis and its role in inflammation and cancer
    • P. Kocabayoglu, and S.L. Friedman Cellular basis of hepatic fibrosis and its role in inflammation and cancer Front Biosci (Schol Ed) 5 2013 217 230
    • (2013) Front Biosci (Schol Ed) , vol.5 , pp. 217-230
    • Kocabayoglu, P.1    Friedman, S.L.2
  • 107
    • 84888339170 scopus 로고    scopus 로고
    • Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology
    • I. Mederacke, C.C. Hsu, and J.S. Troeger et al. Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology Nat Commun 4 2013 2823
    • (2013) Nat Commun , vol.4 , pp. 2823
    • Mederacke, I.1    Hsu, C.C.2    Troeger, J.S.3
  • 108
    • 72949124641 scopus 로고    scopus 로고
    • Chemokine (C-C motif) receptors in fibrogenesis and hepatic regeneration following acute and chronic liver disease
    • G.A. Ramm Chemokine (C-C motif) receptors in fibrogenesis and hepatic regeneration following acute and chronic liver disease Hepatology 50 2009 1664 1668
    • (2009) Hepatology , vol.50 , pp. 1664-1668
    • Ramm, G.A.1
  • 110
    • 70349538626 scopus 로고    scopus 로고
    • Monocytes and macrophages as cellular targets in liver fibrosis
    • F. Heymann, C. Trautwein, and F. Tacke Monocytes and macrophages as cellular targets in liver fibrosis Inflamm Allergy Drug Targets 8 2009 307 318
    • (2009) Inflamm Allergy Drug Targets , vol.8 , pp. 307-318
    • Heymann, F.1    Trautwein, C.2    Tacke, F.3
  • 111
    • 0027360267 scopus 로고
    • Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines
    • F. Marra, A.J. Valente, and M. Pinzani et al. Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines J Clin Invest 92 1993 1674 1680 (Pubitemid 23304529)
    • (1993) Journal of Clinical Investigation , vol.92 , Issue.4 , pp. 1674-1680
    • Marra, F.1    Valente, A.J.2    Pinzani, M.3    Abboud, H.E.4
  • 113
    • 65649094468 scopus 로고    scopus 로고
    • Dual role of CCR2 in the constitution and the resolution of liver fibrosis in mice
    • C. Mitchell, D. Couton, and J.P. Couty et al. Dual role of CCR2 in the constitution and the resolution of liver fibrosis in mice Am J Pathol 174 2009 1766 1775
    • (2009) Am J Pathol , vol.174 , pp. 1766-1775
    • Mitchell, C.1    Couton, D.2    Couty, J.P.3
  • 114
    • 67651156353 scopus 로고    scopus 로고
    • CCR2 promotes hepatic fibrosis in mice
    • E. Seki, S. de Minicis, and S. Inokuchi et al. CCR2 promotes hepatic fibrosis in mice Hepatology 50 2009 185 197
    • (2009) Hepatology , vol.50 , pp. 185-197
    • Seki, E.1    De Minicis, S.2    Inokuchi, S.3
  • 115
    • 84894072682 scopus 로고    scopus 로고
    • CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis
    • [Epub ahead of print]
    • J. Ehling, M. Bartneck, and X. Wei et al. CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis Gut 2014 Feb 21 [Epub ahead of print]
    • (2014) Gut
    • Ehling, J.1    Bartneck, M.2    Wei, X.3
  • 116
    • 84884984479 scopus 로고    scopus 로고
    • Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice
    • J.P. Pradere, J. Kluwe, and S. De Minicis et al. Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice Hepatology 58 2013 1461 1473
    • (2013) Hepatology , vol.58 , pp. 1461-1473
    • Pradere, J.P.1    Kluwe, J.2    De Minicis, S.3
  • 117
    • 84872159959 scopus 로고    scopus 로고
    • Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics
    • E. Liaskou, H.W. Zimmermann, and K.K. Li et al. Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics Hepatology 57 2013 385 398
    • (2013) Hepatology , vol.57 , pp. 385-398
    • Liaskou, E.1    Zimmermann, H.W.2    Li, K.K.3
  • 118
    • 77955096540 scopus 로고    scopus 로고
    • Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis
    • H.W. Zimmermann, S. Seidler, and J. Nattermann et al. Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis PLoS One 5 2010 e11049
    • (2010) PLoS One , vol.5 , pp. 11049
    • Zimmermann, H.W.1    Seidler, S.2    Nattermann, J.3
  • 119
    • 84879605804 scopus 로고    scopus 로고
    • C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice
    • P.S. Chu, N. Nakamoto, and H. Ebinuma et al. C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice Hepatology 58 2013 337 350
    • (2013) Hepatology , vol.58 , pp. 337-350
    • Chu, P.S.1    Nakamoto, N.2    Ebinuma, H.3
  • 120
    • 79959382649 scopus 로고    scopus 로고
    • Interleukin-8 is activated in patients with chronic liver diseases and associated with hepatic macrophage accumulation in human liver fibrosis
    • H.W. Zimmermann, S. Seidler, and N. Gassler et al. Interleukin-8 is activated in patients with chronic liver diseases and associated with hepatic macrophage accumulation in human liver fibrosis PLoS One 6 2011 e21381
    • (2011) PLoS One , vol.6 , pp. 21381
    • Zimmermann, H.W.1    Seidler, S.2    Gassler, N.3
  • 122
    • 84896405331 scopus 로고    scopus 로고
    • A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse
    • A. Moles, L. Murphy, and C.L. Wilson et al. A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse J Hepatol 60 2014 782 791
    • (2014) J Hepatol , vol.60 , pp. 782-791
    • Moles, A.1    Murphy, L.2    Wilson, C.L.3
  • 123
    • 68849118799 scopus 로고    scopus 로고
    • CCR1 and CCR5 promote hepatic fibrosis in mice
    • E. Seki, S. De Minicis, and G.Y. Gwak et al. CCR1 and CCR5 promote hepatic fibrosis in mice J Clin Invest 119 2009 1858 1870
    • (2009) J Clin Invest , vol.119 , pp. 1858-1870
    • Seki, E.1    De Minicis, S.2    Gwak, G.Y.3
  • 124
    • 78049415469 scopus 로고    scopus 로고
    • Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice
    • M.L. Berres, R.R. Koenen, and A. Rueland et al. Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice J Clin Invest 120 2010 4129 4140
    • (2010) J Clin Invest , vol.120 , pp. 4129-4140
    • Berres, M.L.1    Koenen, R.R.2    Rueland, A.3
  • 125
    • 84879174817 scopus 로고    scopus 로고
    • The chemokine CCL3 promotes experimental liver fibrosis in mice
    • D. Heinrichs, M.L. Berres, and A. Nellen et al. The chemokine CCL3 promotes experimental liver fibrosis in mice PLoS One 8 2013 e66106
    • (2013) PLoS One , vol.8 , pp. 66106
    • Heinrichs, D.1    Berres, M.L.2    Nellen, A.3
  • 126
    • 0142244129 scopus 로고    scopus 로고
    • Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration
    • R.F. Schwabe, R. Bataller, and D.A. Brenner Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration Am J Physiol Gastrointest Liver Physiol 285 2003 G949 G958
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.285
    • Schwabe, R.F.1    Bataller, R.2    Brenner, D.A.3
  • 127
    • 68949122522 scopus 로고    scopus 로고
    • Hepatic stellate cells express functional CXCR4: Role in stromal cell-derived factor-1alpha-mediated stellate cell activation
    • F. Hong, A. Tuyama, and T.F. Lee et al. Hepatic stellate cells express functional CXCR4: role in stromal cell-derived factor-1alpha-mediated stellate cell activation Hepatology 49 2009 2055 2067
    • (2009) Hepatology , vol.49 , pp. 2055-2067
    • Hong, F.1    Tuyama, A.2    Lee, T.F.3
  • 128
    • 77950814587 scopus 로고    scopus 로고
    • Gp120 modulates the biology of human hepatic stellate cells: A link between HIV infection and liver fibrogenesis
    • R. Bruno, S. Galastri, and P. Sacchi et al. gp120 modulates the biology of human hepatic stellate cells: a link between HIV infection and liver fibrogenesis Gut 59 2010 513 520
    • (2010) Gut , vol.59 , pp. 513-520
    • Bruno, R.1    Galastri, S.2    Sacchi, P.3
  • 129
    • 84858992663 scopus 로고    scopus 로고
    • X4 Human immunodeficiency virus type 1 gp120 promotes human hepatic stellate cell activation and collagen i expression through interactions with CXCR4
    • F. Hong, Y. Saiman, and C. Si et al. X4 Human immunodeficiency virus type 1 gp120 promotes human hepatic stellate cell activation and collagen I expression through interactions with CXCR4 PLoS One 7 2012 e33659
    • (2012) PLoS One , vol.7 , pp. 33659
    • Hong, F.1    Saiman, Y.2    Si, C.3
  • 130
    • 84892370936 scopus 로고    scopus 로고
    • Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis
    • B.S. Ding, Z. Cao, and R. Lis et al. Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis Nature 505 2014 97 102
    • (2014) Nature , vol.505 , pp. 97-102
    • Ding, B.S.1    Cao, Z.2    Lis, R.3
  • 131
    • 67649183610 scopus 로고    scopus 로고
    • Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans
    • 319 e1-e3
    • H.E. Wasmuth, F. Lammert, and M.M. Zaldivar et al. Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans Gastroenterology 137 2009 309 319 319 e1-e3
    • (2009) Gastroenterology , vol.137 , pp. 309-319
    • Wasmuth, H.E.1    Lammert, F.2    Zaldivar, M.M.3
  • 132
    • 84859969340 scopus 로고    scopus 로고
    • Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice
    • H. Sahin, E. Borkham-Kamphorst, and C. Kuppe et al. Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice Hepatology 55 2012 1610 1619
    • (2012) Hepatology , vol.55 , pp. 1610-1619
    • Sahin, H.1    Borkham-Kamphorst, E.2    Kuppe, C.3
  • 133
    • 77958154113 scopus 로고    scopus 로고
    • CXCL10 promotes liver fibrosis by prevention of NK cell mediated hepatic stellate cell inactivation
    • E. Hintermann, M. Bayer, and J.M. Pfeilschifter et al. CXCL10 promotes liver fibrosis by prevention of NK cell mediated hepatic stellate cell inactivation J Autoimmun 35 2010 424 435
    • (2010) J Autoimmun , vol.35 , pp. 424-435
    • Hintermann, E.1    Bayer, M.2    Pfeilschifter, J.M.3
  • 135
    • 84869208905 scopus 로고    scopus 로고
    • Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis
    • P. Ramachandran, A. Pellicoro, and M.A. Vernon et al. Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis Proc Natl Acad Sci U S A 109 2012 E3186 E3195
    • (2012) Proc Natl Acad Sci U S A , vol.109
    • Ramachandran, P.1    Pellicoro, A.2    Vernon, M.A.3
  • 136
    • 84866692545 scopus 로고    scopus 로고
    • Deactivation of hepatic stellate cells during liver fibrosis resolution in mice
    • J.S. Troeger, I. Mederacke, and G.Y. Gwak et al. Deactivation of hepatic stellate cells during liver fibrosis resolution in mice Gastroenterology 143 2012 1073 1083.e22
    • (2012) Gastroenterology , vol.143
    • Troeger, J.S.1    Mederacke, I.2    Gwak, G.Y.3
  • 137
    • 84862195154 scopus 로고    scopus 로고
    • Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
    • T. Kisseleva, M. Cong, and Y. Paik et al. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis Proc Natl Acad Sci U S A 109 2012 9448 9453
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 9448-9453
    • Kisseleva, T.1    Cong, M.2    Paik, Y.3
  • 138
    • 84898789996 scopus 로고    scopus 로고
    • Macrophage heterogeneity in liver injury and fibrosis
    • F. Tacke, and H.W. Zimmermann Macrophage heterogeneity in liver injury and fibrosis J Hepatol 60 2014 1090 1096
    • (2014) J Hepatol , vol.60 , pp. 1090-1096
    • Tacke, F.1    Zimmermann, H.W.2
  • 139
    • 84896707511 scopus 로고    scopus 로고
    • Pharmacological inhibition of the chemokine C-C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly-6C macrophage infiltration in mice
    • C. Baeck, X. Wei, and M. Bartneck et al. Pharmacological inhibition of the chemokine C-C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly-6C macrophage infiltration in mice Hepatology 59 2014 1060 1072
    • (2014) Hepatology , vol.59 , pp. 1060-1072
    • Baeck, C.1    Wei, X.2    Bartneck, M.3
  • 140
    • 84879189428 scopus 로고    scopus 로고
    • Met-CCL5 modifies monocyte subpopulations during liver fibrosis regression
    • M.K. Stock, L. Hammerich, and O.N. do et al. Met-CCL5 modifies monocyte subpopulations during liver fibrosis regression Int J Clin Exp Pathol 6 2013 678 685
    • (2013) Int J Clin Exp Pathol , vol.6 , pp. 678-685
    • Stock, M.K.1    Hammerich, L.2    Do, O.N.3
  • 141
    • 84875989422 scopus 로고    scopus 로고
    • The multifaceted role of the microenvironment in liver metastasis: Biology and clinical implications
    • G.G. Van den Eynden, A.W. Majeed, and M. Illemann et al. The multifaceted role of the microenvironment in liver metastasis: biology and clinical implications Cancer Res 73 2013 2031 2043
    • (2013) Cancer Res , vol.73 , pp. 2031-2043
    • Van Den Eynden, G.G.1    Majeed, A.W.2    Illemann, M.3
  • 142
    • 0033038824 scopus 로고    scopus 로고
    • Expression and function of CXC and CC chemokines in human malignant liver tumors: A role for human monokine induced by γ-interferon in lymphocyte recruitment to hepatocellular carcinoma
    • DOI 10.1002/hep.510300147
    • P. Aujla, S. Qin, and K. Price et al. Expression and function of CXC and CC chemokines in human malignant liver tumors: a role for human monokine induced by gamma-interferon in lymphocyte recruitment to hepatocellular carcinoma Hepatology 30 1999 100 111 (Pubitemid 29300575)
    • (1999) Hepatology , vol.30 , Issue.1 , pp. 100-111
    • Yoong, K.E.1    Afford, S.C.2    Jones, R.3    Aujla, P.4    Qin, S.5    Price, K.6    Hubscher, S.G.7    Adams, D.H.8
  • 143
    • 0346103807 scopus 로고    scopus 로고
    • Interleukin-8 Serum Levels in Patients with Hepatocellular Carcinoma: Correlations with Clinicopathological Features and Prognosis
    • Y. Ren, R.T. Poon, and H.T. Tsui et al. Interleukin-8 serum levels in patients with hepatocellular carcinoma: correlations with clinicopathological features and prognosis Clin Cancer Res 9 2003 5996 6001 (Pubitemid 38018086)
    • (2003) Clinical Cancer Research , vol.9 , Issue.16 , pp. 5996-6001
    • Ren, Y.1    Poon, R.T.-P.2    Tsui, H.-T.3    Chen, W.-H.4    Li, Z.5    Lau, C.6    Yu, W.-C.7    Fan, S.-T.8
  • 144
    • 79954657385 scopus 로고    scopus 로고
    • Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma
    • D.M. Kuang, Q. Zhao, and Y. Wu et al. Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma J Hepatol 54 2011 948 955
    • (2011) J Hepatol , vol.54 , pp. 948-955
    • Kuang, D.M.1    Zhao, Q.2    Wu, Y.3
  • 145
    • 84862777489 scopus 로고    scopus 로고
    • CD133(+) liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling
    • K.H. Tang, S. Ma, and T.K. Lee et al. CD133(+) liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling Hepatology 55 2012 807 820
    • (2012) Hepatology , vol.55 , pp. 807-820
    • Tang, K.H.1    Ma, S.2    Lee, T.K.3
  • 146
    • 84870514368 scopus 로고    scopus 로고
    • Overexpression of CXCL5 mediates neutrophil infiltration and indicates poor prognosis for hepatocellular carcinoma
    • S.L. Zhou, Z. Dai, and Z.J. Zhou et al. Overexpression of CXCL5 mediates neutrophil infiltration and indicates poor prognosis for hepatocellular carcinoma Hepatology 56 2012 2242 2254
    • (2012) Hepatology , vol.56 , pp. 2242-2254
    • Zhou, S.L.1    Dai, Z.2    Zhou, Z.J.3
  • 147
    • 33846985321 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1/chemokine (C-X-C motif) ligand 12 stimulates human hepatoma cell growth, migration, and invasion
    • A. Sutton, V. Friand, and S. Brule-Donneger et al. Stromal cell-derived factor-1/chemokine (C-X-C motif) ligand 12 stimulates human hepatoma cell growth, migration, and invasion Mol Cancer Res 5 2007 21 33
    • (2007) Mol Cancer Res , vol.5 , pp. 21-33
    • Sutton, A.1    Friand, V.2    Brule-Donneger, S.3
  • 148
    • 67650246591 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4 expression in hepatocellular carcinoma patients increases the risk of bone metastases and poor survival
    • Z.L. Xiang, Z.C. Zeng, and Z.Y. Tang et al. Chemokine receptor CXCR4 expression in hepatocellular carcinoma patients increases the risk of bone metastases and poor survival BMC Cancer 9 2009 176
    • (2009) BMC Cancer , vol.9 , pp. 176
    • Xiang, Z.L.1    Zeng, Z.C.2    Tang, Z.Y.3
  • 149
    • 82155188524 scopus 로고    scopus 로고
    • Urokinase induces stromal cell-derived factor-1 expression in human hepatocellular carcinoma cells
    • W.H. Hsu, C.N. Chen, and H.I. Huang et al. Urokinase induces stromal cell-derived factor-1 expression in human hepatocellular carcinoma cells J Cell Physiol 227 2012 697 704
    • (2012) J Cell Physiol , vol.227 , pp. 697-704
    • Hsu, W.H.1    Chen, C.N.2    Huang, H.I.3
  • 150
    • 80052316134 scopus 로고    scopus 로고
    • Osteopontin enhances the expression and activity of MMP-2 via the SDF-1/CXCR4 axis in hepatocellular carcinoma cell lines
    • R. Zhang, X. Pan, and Z. Huang et al. Osteopontin enhances the expression and activity of MMP-2 via the SDF-1/CXCR4 axis in hepatocellular carcinoma cell lines PLoS One 6 2011 e23831
    • (2011) PLoS One , vol.6 , pp. 23831
    • Zhang, R.1    Pan, X.2    Huang, Z.3
  • 151
    • 84857050018 scopus 로고    scopus 로고
    • Chemokine-driven lymphocyte infiltration: An early intratumoural event determining long-term survival in resectable hepatocellular carcinoma
    • V. Chew, J. Chen, and D. Lee et al. Chemokine-driven lymphocyte infiltration: an early intratumoural event determining long-term survival in resectable hepatocellular carcinoma Gut 61 2012 427 438
    • (2012) Gut , vol.61 , pp. 427-438
    • Chew, V.1    Chen, J.2    Lee, D.3
  • 152
    • 84888286377 scopus 로고    scopus 로고
    • Overactivation of the TGF-beta pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells
    • E. Bertran, E. Crosas-Molist, and P. Sancho et al. Overactivation of the TGF-beta pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells Hepatology 58 2013 2032 2044
    • (2013) Hepatology , vol.58 , pp. 2032-2044
    • Bertran, E.1    Crosas-Molist, E.2    Sancho, P.3
  • 153
    • 79954606458 scopus 로고    scopus 로고
    • CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: An emerging sensitizer for anticancer therapies?
    • D.G. Duda, S.V. Kozin, and N.D. Kirkpatrick et al. CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies? Clin Cancer Res 17 2011 2074 2080
    • (2011) Clin Cancer Res , vol.17 , pp. 2074-2080
    • Duda, D.G.1    Kozin, S.V.2    Kirkpatrick, N.D.3
  • 154
    • 84894456273 scopus 로고    scopus 로고
    • New nomenclature for atypical chemokine receptors
    • F. Bachelerie, G.J. Graham, and M. Locati et al. New nomenclature for atypical chemokine receptors Nat Immunol 15 2014 207 208
    • (2014) Nat Immunol , vol.15 , pp. 207-208
    • Bachelerie, F.1    Graham, G.J.2    Locati, M.3
  • 156
    • 33645242233 scopus 로고    scopus 로고
    • Essential contribution of a chemokine, CCL3, and its receptor, CCR1, to hepatocellular carcinoma progression
    • X. Yang, P. Lu, and C. Fujii et al. Essential contribution of a chemokine, CCL3, and its receptor, CCR1, to hepatocellular carcinoma progression Int J Cancer 118 2006 1869 1876
    • (2006) Int J Cancer , vol.118 , pp. 1869-1876
    • Yang, X.1    Lu, P.2    Fujii, C.3
  • 157
    • 84872245893 scopus 로고    scopus 로고
    • Maraviroc, a CCR5 antagonist, prevents development of hepatocellular carcinoma in a mouse model
    • L. Ochoa-Callejero, L. Perez-Martinez, and S. Rubio-Mediavilla et al. Maraviroc, a CCR5 antagonist, prevents development of hepatocellular carcinoma in a mouse model PLoS One 8 2013 e53992
    • (2013) PLoS One , vol.8 , pp. 53992
    • Ochoa-Callejero, L.1    Perez-Martinez, L.2    Rubio-Mediavilla, S.3
  • 158
    • 77955741107 scopus 로고    scopus 로고
    • Antitumor effect after radiofrequency ablation of murine hepatoma is augmented by an active variant of CC Chemokine ligand 3/macrophage inflammatory protein-1alpha
    • N. Iida, Y. Nakamoto, and T. Baba et al. Antitumor effect after radiofrequency ablation of murine hepatoma is augmented by an active variant of CC Chemokine ligand 3/macrophage inflammatory protein-1alpha Cancer Res 70 2010 6556 6565
    • (2010) Cancer Res , vol.70 , pp. 6556-6565
    • Iida, N.1    Nakamoto, Y.2    Baba, T.3
  • 160
    • 80052827580 scopus 로고    scopus 로고
    • Selective recruitment of regulatory T cell through CCR6-CCL20 in hepatocellular carcinoma fosters tumor progression and predicts poor prognosis
    • K.J. Chen, S.Z. Lin, and L. Zhou et al. Selective recruitment of regulatory T cell through CCR6-CCL20 in hepatocellular carcinoma fosters tumor progression and predicts poor prognosis PLoS One 6 2011 e24671
    • (2011) PLoS One , vol.6 , pp. 24671
    • Chen, K.J.1    Lin, S.Z.2    Zhou, L.3
  • 161
    • 84866018690 scopus 로고    scopus 로고
    • TGF-beta-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma
    • P. Yang, Q.J. Li, and Y. Feng et al. TGF-beta-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma Cancer Cell 22 2012 291 303
    • (2012) Cancer Cell , vol.22 , pp. 291-303
    • Yang, P.1    Li, Q.J.2    Feng, Y.3
  • 162
    • 84868706854 scopus 로고    scopus 로고
    • Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer
    • C. Schneider, A. Teufel, and T. Yevsa et al. Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer Gut 61 2012 1733 1743
    • (2012) Gut , vol.61 , pp. 1733-1743
    • Schneider, C.1    Teufel, A.2    Yevsa, T.3
  • 163
    • 84866399814 scopus 로고    scopus 로고
    • Role of the stromal-derived factor-1 (SDF-1)-CXCR4 axis in the interaction between hepatic stellate cells and cholangiocarcinoma
    • A. Gentilini, K. Rombouts, and S. Galastri et al. Role of the stromal-derived factor-1 (SDF-1)-CXCR4 axis in the interaction between hepatic
    • (2012) J Hepatol , vol.57 , pp. 813-820
    • Gentilini, A.1    Rombouts, K.2    Galastri, S.3
  • 164
    • 84867072533 scopus 로고    scopus 로고
    • Identification of CXCL5/ENA-78 as a factor involved in the interaction between cholangiocarcinoma cells and cancer-associated fibroblasts
    • H. Okabe, T. Beppu, and M. Ueda et al. Identification of CXCL5/ENA-78 as a factor involved in the interaction between cholangiocarcinoma cells and cancer-associated fibroblasts Int J Cancer 131 2012 2234 2241
    • (2012) Int J Cancer , vol.131 , pp. 2234-2241
    • Okabe, H.1    Beppu, T.2    Ueda, M.3
  • 165
    • 84906558405 scopus 로고    scopus 로고
    • Significant anti-fibrotic activity of cenicriviroc, a dual CCR2/CCR5 antagonist, in a rat model of thioacetamide-induced liver fibrosis and cirrhosis
    • F. Hong, H. Chou, and S.L. Friedman Significant anti-fibrotic activity of cenicriviroc, a dual CCR2/CCR5 antagonist, in a rat model of thioacetamide-induced liver fibrosis and cirrhosis Hepatology 58 suppl 6 2013 1381A
    • (2013) Hepatology , vol.58 , Issue.SUPPL. 6
    • Hong, F.1    Chou, H.2    Friedman, S.L.3
  • 166
    • 84874967707 scopus 로고    scopus 로고
    • CXCR3 axis in patients with primary biliary cirrhosis: A possible novel mechanism of the effect of ursodeoxycholic acid
    • P. Manousou, G. Kolios, and I. Drygiannakis et al. CXCR3 axis in patients with primary biliary cirrhosis: a possible novel mechanism of the effect of ursodeoxycholic acid Clin Exp Immunol 172 2013 9 15
    • (2013) Clin Exp Immunol , vol.172 , pp. 9-15
    • Manousou, P.1    Kolios, G.2    Drygiannakis, I.3
  • 167
    • 84875019579 scopus 로고    scopus 로고
    • CC chemokine receptors and chronic inflammation-therapeutic opportunities and pharmacological challenges
    • G.E. White, A.J. Iqbal, and D.R. Greaves CC chemokine receptors and chronic inflammation-therapeutic opportunities and pharmacological challenges Pharmacol Rev 65 2013 47 89
    • (2013) Pharmacol Rev , vol.65 , pp. 47-89
    • White, G.E.1    Iqbal, A.J.2    Greaves, D.R.3
  • 168
    • 84887006703 scopus 로고    scopus 로고
    • CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice
    • T. Sullivan, Z. Miao, and D.J. Dairaghi et al. CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice Am J Physiol Renal Physiol 305 2013 F1288 F1297
    • (2013) Am J Physiol Renal Physiol , vol.305
    • Sullivan, T.1    Miao, Z.2    Dairaghi, D.J.3
  • 169
    • 84877292439 scopus 로고    scopus 로고
    • The downstream regulation of chemokine receptor signalling: Implications for atherosclerosis
    • J. Patel, K.M. Channon, and E. McNeill The downstream regulation of chemokine receptor signalling: implications for atherosclerosis Mediators Inflamm 2013 2013 459520
    • (2013) Mediators Inflamm , vol.2013 , pp. 459520
    • Patel, J.1    Channon, K.M.2    McNeill, E.3
  • 170
    • 85011940682 scopus 로고    scopus 로고
    • Site-specific metastasis formation: Chemokines as regulators of tumor cell adhesion, motility and invasion
    • A. Ben-Baruch Site-specific metastasis formation: chemokines as regulators of tumor cell adhesion, motility and invasion Cell Adh Migr 3 2009 328 333
    • (2009) Cell Adh Migr , vol.3 , pp. 328-333
    • Ben-Baruch, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.