-
1
-
-
10744228014
-
Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong People's Republic of China, in February, 2003
-
Zhong, N. S. et al. Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003. Lancet 362, 1353-1358 (2003).
-
(2003)
Lancet
, vol.362
, pp. 1353-1358
-
-
Zhong, N.S.1
-
2
-
-
0013074820
-
A major outbreak of severe acute respiratory syndrome in Hong Kong
-
Lee, N. et al. A major outbreak of severe acute respiratory syndrome in Hong Kong. N. Engl. J. Med. 348, 1986-1994 (2003).
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1986-1994
-
-
Lee, N.1
-
3
-
-
9144249102
-
Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome
-
Guan, Y. et al. Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome. Lancet 363, 99-104 (2004).
-
(2004)
Lancet
, vol.363
, pp. 99-104
-
-
Guan, Y.1
-
4
-
-
0038523806
-
Identification of a novel coronavirus in patients with severe acute respiratory syndrome
-
Drosten, C. et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N. Engl. J. Med. 348, 1967-1976 (2003).
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1967-1976
-
-
Drosten, C.1
-
5
-
-
0038076030
-
A novel coronavirus associated with severe acute respiratory syndrome
-
Ksiazek, T. G. et al. A novel coronavirus associated with severe acute respiratory syndrome. N. Engl. J. Med. 348, 1953-1966 (2003).
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1953-1966
-
-
Ksiazek, T.G.1
-
6
-
-
0242717589
-
Coronavirus as a possible cause of severe acute respiratory syndrome
-
Peiris, J. S. et al. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet 361, 1319-1325 (2003).
-
(2003)
Lancet
, vol.361
, pp. 1319-1325
-
-
Peiris, J.S.1
-
8
-
-
33644819689
-
SARS-CoV infection in a restaurant from palm civet
-
Wang, M. et al. SARS-CoV infection in a restaurant from palm civet. Emerg. Infect. Dis. 11 , 1860-1865 (2005).
-
(2005)
Emerg. Infect. Dis.
, vol.11
, pp. 1860-1865
-
-
Wang, M.1
-
9
-
-
84889573658
-
Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor
-
Ge, X. Y. et al. Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor. Nature 503, 535-538 (2013).
-
(2013)
Nature
, vol.503
, pp. 535-538
-
-
Ge, X.Y.1
-
10
-
-
84949623850
-
A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
-
Menachery, V. D. et al. A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nat. Med. 21, 1508-1513 (2015).
-
(2015)
Nat. Med.
, vol.21
, pp. 1508-1513
-
-
Menachery, V.D.1
-
11
-
-
84868516062
-
Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia
-
Zaki, A. M., van Boheemen, S., Bestebroer, T. M., Osterhaus, A. D. & Fouchier, R. A. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N. Engl. J. Med. 367, 1814-1820 (2012).
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 1814-1820
-
-
Zaki, A.M.1
Van Boheemen, S.2
Bestebroer, T.M.3
Osterhaus, A.D.4
Fouchier, R.A.5
-
12
-
-
84940313968
-
Novel coronavirus infections in Jordan, April 2012: Epidemiological findings from a retrospective investigation
-
Hijawi, B. et al. Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation. East. Mediterr. Health J. 19 (Suppl. 1), S12-S18 (2013).
-
(2013)
East. Mediterr. Health J.
, vol.19
, pp. S12-S18
-
-
Hijawi, B.1
-
13
-
-
84871860149
-
Patient with new strain of coronavirus is treated in intensive care at London hospital
-
Wise, J. Patient with new strain of coronavirus is treated in intensive care at London hospital. BMJ 345, e6455 (2012).
-
(2012)
BMJ
, vol.345
, pp. e6455
-
-
Wise, J.1
-
14
-
-
84942198680
-
Middle East respiratory syndrome coronavirus outbreak in the Republic of Korea 2015
-
Korea Centers for Disease Control and Prevention. Middle East respiratory syndrome coronavirus outbreak in the Republic of Korea, 2015. Osong Public Health Res. Perspect. 6, 269-278 (2015).
-
(2015)
Osong Public Health Res. Perspect.
, vol.6
, pp. 269-278
-
-
-
16
-
-
33744789955
-
Nidovirus transcription: How to make sense?
-
Pasternak, A. O., Spaan, W J. & Snijder, E. J. Nidovirus transcription: how to make sense? J. Gen. Virol. 87, 1403-1421 (2006).
-
(2006)
J. Gen. Virol.
, vol.87
, pp. 1403-1421
-
-
Pasternak, A.O.1
Spaan, W.J.2
Snijder, E.J.3
-
17
-
-
67349158649
-
Coronaviruses post-SARS: Update on replication and pathogenesis
-
Perlman, S. & Netland, J. Coronaviruses post-SARS: update on replication and pathogenesis. Nat. Rev. Microbiol. 7, 439-450 (2009).
-
(2009)
Nat. Rev. Microbiol.
, vol.7
, pp. 439-450
-
-
Perlman, S.1
Netland, J.2
-
18
-
-
84924043245
-
Coronaviruses: An overview of their replication and pathogenesis
-
Fehr, A. R. & Perlman, S. Coronaviruses: an overview of their replication and pathogenesis. Methods Mol. Biol. 1282, 1-23 (2015).
-
(2015)
Methods Mol. Biol.
, vol.1282
, pp. 1-23
-
-
Fehr, A.R.1
Perlman, S.2
-
19
-
-
54749157085
-
SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum
-
Knoops, K. et al. SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum. PLoS Biol. 6, e226 (2008).
-
(2008)
PLoS Biol.
, vol.6
, pp. e226
-
-
Knoops, K.1
-
20
-
-
0042164218
-
Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage
-
Snijder, E. J. et al. Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage. J. Mol Biol. 331, 991-1004 (2003).
-
(2003)
J. Mol Biol.
, vol.331
, pp. 991-1004
-
-
Snijder, E.J.1
-
21
-
-
77954055072
-
Infidelity of SARS-CoV nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing
-
Eckerle, L. D. et al. Infidelity of SARS-CoV nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing. PLoS Pathog. 6, e1000896 (2010).
-
(2010)
PLoS Pathog.
, vol.6
, pp. e1000896
-
-
Eckerle, L.D.1
-
22
-
-
84920567563
-
Insights into RNA synthesis capping, and proofreading mechanisms of SARS-coronavirus
-
Sevajol, M., Subissi, L, Decroly, E., Canard, B. & Imbert, I. Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirus. Virus Res. 194, 90-99 (2014).
-
(2014)
Virus Res.
, vol.194
, pp. 90-99
-
-
Sevajol, M.1
Subissi, L.2
Decroly, E.3
Canard, B.4
Imbert, I.5
-
23
-
-
84874996988
-
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
-
Raj, V. S. et al. Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature 495, 251-254 (2013).
-
(2013)
Nature
, vol.495
, pp. 251-254
-
-
Raj, V.S.1
-
24
-
-
0004250834
-
-
(eds Knipe D. M. & Howley P. M.) Wolters Kluwer
-
Masters, P. S. & Perlman, S. in Fields Virology (eds Knipe, D. M. & Howley, P. M.) 825-858 (Wolters Kluwer, 2013).
-
(2013)
Fields Virology
, pp. 825-858
-
-
Masters, P.S.1
Perlman, S.2
-
25
-
-
0141889936
-
Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China
-
Guan, Y. et al. Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. Science 302, 276-278 (2003).
-
(2003)
Science
, vol.302
, pp. 276-278
-
-
Guan, Y.1
-
26
-
-
33845459178
-
Review of bats and SARS
-
Wang, L. F. et al. Review of bats and SARS. Emerg. Infect. Dis. 12, 1834-1840 (2006).
-
(2006)
Emerg. Infect. Dis.
, vol.12
, pp. 1834-1840
-
-
Wang, L.F.1
-
27
-
-
84888115990
-
Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS
-
Drexler, J. F. , Corman, V. M. & Drosten, C. Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS. Antiviral Res. 101, 45-56 (2014).
-
(2014)
Antiviral Res.
, vol.101
, pp. 45-56
-
-
Drexler, J.F.1
Corman, V.M.2
Drosten, C.3
-
28
-
-
84884377173
-
Middle East respiratory syndrome coronavirus neutralizing serum antibodies in dromedary camels: A comparative serological study
-
Reusken, C. B. et al. Middle East respiratory syndrome coronavirus neutralizing serum antibodies in dromedary camels: a comparative serological study. Lancet Infect. Dis. 13, 859-866 (2013).
-
(2013)
Lancet Infect. Dis.
, vol.13
, pp. 859-866
-
-
Reusken, C.B.1
-
29
-
-
84892538696
-
Middle East respiratory syndrome coronavirus in dromedary camels: An outbreak investigation
-
Haagmans, B. L. et al. Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation. Lancet Infect. Dis. 14, 140-145 (2014).
-
(2014)
Lancet Infect. Dis.
, vol.14
, pp. 140-145
-
-
Haagmans, B.L.1
-
30
-
-
84903435220
-
Evidence for camel-to-human transmission of MERS coronavirus
-
Azhar, E. I. et al. Evidence for camel-to-human transmission of MERS coronavirus. N. Engl. J. Med. 370, 2499-2505 (2014).
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 2499-2505
-
-
Azhar, E.I.1
-
31
-
-
84901443765
-
MERS coronavirus in dromedary camel herd, Saudi Arabia
-
Hemida, M. G. et al. MERS coronavirus in dromedary camel herd, Saudi Arabia. Emerg. Infect. Dis. 20, 1231-1234 (2014).
-
(2014)
Emerg. Infect. Dis.
, vol.20
, pp. 1231-1234
-
-
Hemida, M.G.1
-
32
-
-
84902277248
-
Isolation of MERS coronavirus from a dromedary camel, Qatar 2014
-
Raj, V. S. et al. Isolation of MERS coronavirus from a dromedary camel, Qatar, 2014. Emerg. Infect. Dis. 20, 1339-1342 (2014).
-
(2014)
Emerg. Infect. Dis.
, vol.20
, pp. 1339-1342
-
-
Raj, V.S.1
-
33
-
-
84922417149
-
MERS coronavirus neutralizing antibodies in camels, Eastern Africa 1983-1997
-
Muller, M. A. et al. MERS coronavirus neutralizing antibodies in camels, Eastern Africa, 1983-1997. Emerg. Infect. Dis. 20, 2093-2095 (2014).
-
(2014)
Emerg. Infect. Dis.
, vol.20
, pp. 2093-2095
-
-
Muller, M.A.1
-
34
-
-
84952951392
-
Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia
-
Sabir, J. S. et al. Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia. Science 351, 81-84 (2016).
-
(2016)
Science
, vol.351
, pp. 81-84
-
-
Sabir, J.S.1
-
35
-
-
84941261132
-
Transmission characteristics of MERS and SARS in the healthcare setting: A comparative study
-
Chowell, G. et al. Transmission characteristics of MERS and SARS in the healthcare setting: a comparative study. BMC Med. 13, 210 (2015).
-
(2015)
BMC Med.
, vol.13
, pp. 210
-
-
Chowell, G.1
-
36
-
-
84961210719
-
Transmission of Middle East respiratory syndrome coronavirus infections in healthcare settings, Abu Dhabi
-
Hunter, J. C. et al. Transmission of Middle East respiratory syndrome coronavirus infections in healthcare settings, Abu Dhabi. Emerg. Infect. Dis. 22, 647-656 (2016).
-
(2016)
Emerg. Infect. Dis.
, vol.22
, pp. 647-656
-
-
Hunter, J.C.1
-
37
-
-
3242732261
-
Epidemiology, transmission dynamics and control of SARS: The 2002-2003 epidemic
-
Anderson, R. M. et al. Epidemiology, transmission dynamics and control of SARS: the 2002-2003 epidemic. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 359, 1091-1105 (2004).
-
(2004)
Philos. Trans. R. Soc. Lond. B. Biol. Sci.
, vol.359
, pp. 1091-1105
-
-
Anderson, R.M.1
-
38
-
-
84934295654
-
Preliminary epidemiological assessment of MERS-CoV outbreak in South Korea, May to June 2015
-
Cowling, B. J. et al. Preliminary epidemiological assessment of MERS-CoV outbreak in South Korea, May to June 2015. Euro Surveill. 20, 7-13 (2015).
-
(2015)
Euro Surveill.
, vol.20
, pp. 7-13
-
-
Cowling, B.J.1
-
39
-
-
0038362701
-
Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: A prospective study
-
Peiris, J. S. et al. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet 361, 1767-1772 (2003).
-
(2003)
Lancet
, vol.361
, pp. 1767-1772
-
-
Peiris, J.S.1
-
40
-
-
84960194703
-
Environmental contamination and viral shedding in MERS patients during MERS-CoV outbreak in South Korea
-
Bin, S. Y. et al. Environmental contamination and viral shedding in MERS patients during MERS-CoV outbreak in South Korea. Clin. Infect. Dis. 62, 755-760 (2015).
-
(2015)
Clin. Infect. Dis.
, vol.62
, pp. 755-760
-
-
Bin, S.Y.1
-
41
-
-
84946207588
-
The role of superspreading in Middle East respiratory syndrome coronavirus (MERS-CoV) transmission
-
Kucharski, A. J. & Althaus, C. L. The role of superspreading in Middle East respiratory syndrome coronavirus (MERS-CoV) transmission. Euro Surveill. 20, 14-18 (2015).
-
(2015)
Euro Surveill.
, vol.20
, pp. 14-18
-
-
Kucharski, A.J.1
Althaus, C.L.2
-
42
-
-
84946209567
-
Middle East respiratory syndrome coronavirus superspreading event involving 81 persons Korea 2015
-
Oh, M. D. et al. Middle East respiratory syndrome coronavirus superspreading event involving 81 persons, Korea 2015. J. Korean Med. Sci. 30, 1701-1705 (2015).
-
(2015)
J. Korean Med. Sci.
, vol.30
, pp. 1701-1705
-
-
Oh, M.D.1
-
43
-
-
84944255470
-
MERS, SARS, and Ebola: The role of super-spreaders in infectious disease
-
Wong, G. et al. MERS, SARS, and Ebola: the role of super-spreaders in infectious disease. Cell Host Microbe 18, 398-401 (2015).
-
(2015)
Cell Host Microbe
, vol.18
, pp. 398-401
-
-
Wong, G.1
-
44
-
-
84958935377
-
Clinicopathologic immunohistochemical and ultrastructural findings of a fatal case of Middle East respiratory syndrome coronavirus infection in the United Arab Emirates April 2014
-
Ng, D. L. et al. Clinicopathologic, immunohistochemical, and ultrastructural findings of a fatal case of Middle East respiratory syndrome coronavirus infection in the United Arab Emirates, April 2014. Am. J. Pathol. 186, 652-658 (2016).
-
(2016)
Am J. Pathol.
, vol.186
, pp. 652-658
-
-
Ng, D.L.1
-
45
-
-
23844463115
-
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury
-
Kuba, K. et al. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat. Med. 11 , 875-879 (2005).
-
(2005)
Nat. Med.
, vol.11
, pp. 875-879
-
-
Kuba, K.1
-
46
-
-
21844460785
-
Angiotensin-converting enzyme 2 protects from severe acute lung failure
-
Imai, Y. et al. Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature 436, 112-116 (2005).
-
(2005)
Nature
, vol.436
, pp. 112-116
-
-
Imai, Y.1
-
47
-
-
4744370932
-
Temporal relationship of viral load, ribavirin, interleukin (IL)-6, IL-8, and clinical progression in patients with severe acute respiratory syndrome
-
Wang, W. K. et al. Temporal relationship of viral load, ribavirin, interleukin (IL)-6, IL-8, and clinical progression in patients with severe acute respiratory syndrome. Clin. Infect. Dis. 39, 1071-1075 (2004).
-
(2004)
Clin. Infect. Dis.
, vol.39
, pp. 1071-1075
-
-
Wang, W.K.1
-
48
-
-
84882614929
-
Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection
-
Drosten, C. et al. Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection. Lancet Infect. Dis. 13, 745-751 (2013).
-
(2013)
Lancet Infect. Dis.
, vol.13
, pp. 745-751
-
-
Drosten, C.1
-
49
-
-
84924021563
-
Kinetics and pattern of viral excretion in biological specimens of two MERS-CoV cases
-
Poissy, J. et al. Kinetics and pattern of viral excretion in biological specimens of two MERS-CoV cases. J. Clin. Virol. 61, 275-278 (2014).
-
(2014)
J. Clin. Virol.
, vol.61
, pp. 275-278
-
-
Poissy, J.1
-
50
-
-
84895069834
-
Biomarkers in acute respiratory distress syndrome
-
Binnie, A., Tsang, J. L. & dos Santos, C. C. Biomarkers in acute respiratory distress syndrome. Curr. Opin. Crit. Care 20, 47-55 (2014).
-
(2014)
Curr. Opin. Crit. Care
, vol.20
, pp. 47-55
-
-
Binnie, A.1
Tsang, J.L.2
Dos Santos, C.C.3
-
52
-
-
33744470331
-
SARS-CoV virus-host interactions and comparative etiologies of acute respiratory distress syndrome as determined by transcriptional and cytokine profiling of formalin-fixed paraffin-embedded tissues
-
Baas, T. , Taubenberger, J. K., Chong, P. Y., Chui, P. & Katze, M. G. SARS-CoV virus-host interactions and comparative etiologies of acute respiratory distress syndrome as determined by transcriptional and cytokine profiling of formalin-fixed paraffin-embedded tissues. J. Interferon Cytokine Res. 26, 309-317 (2006).
-
(2006)
J. Interferon Cytokine Res.
, vol.26
, pp. 309-317
-
-
Baas, T.1
Taubenberger, J.K.2
Chong, P.Y.3
Chui, P.4
Katze, M.G.5
-
53
-
-
84895823870
-
Distinct immune response in two MERS-CoV-infected patients: Can we go from bench to bedside?
-
Faure, E. et al. Distinct immune response in two MERS-CoV-infected patients: can we go from bench to bedside? PLoS ONE 9, e88716 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e88716
-
-
Faure, E.1
-
54
-
-
70349383903
-
Elucidating the molecular physiopathology of acute respiratory distress syndrome in severe acute respiratory syndrome patients
-
Kong, S. L., Chui, P., Lim, B. & Salto-Tellez, M. Elucidating the molecular physiopathology of acute respiratory distress syndrome in severe acute respiratory syndrome patients. Virus Res. 145, 260-269 (2009).
-
(2009)
Virus Res.
, vol.145
, pp. 260-269
-
-
Kong, S.L.1
Chui, P.2
Lim, B.3
Salto-Tellez, M.4
-
55
-
-
28044458937
-
Early enhanced expression of interferon-inducible protein-10 (CXCL-10) and other chemokines predicts adverse outcome in severe acute respiratory syndrome
-
Tang, N. L. et al. Early enhanced expression of interferon-inducible protein-10 (CXCL-10) and other chemokines predicts adverse outcome in severe acute respiratory syndrome. Clin. Chem. 51, 2333-2340 (2005).
-
(2005)
Clin. Chem.
, vol.51
, pp. 2333-2340
-
-
Tang, N.L.1
-
56
-
-
34547814128
-
Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome
-
Cameron, M. J. et al. Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome. J. Virol. 81, 8692-8706 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 8692-8706
-
-
Cameron, M.J.1
-
57
-
-
84946606810
-
Genome wide identification of SARS-CoV susceptibility loci using the Collaborative Cross
-
Gralinski, L. E. et al. Genome wide identification of SARS-CoV susceptibility loci using the Collaborative Cross. PLoS Genet. 11 , e1005504 (2015).
-
(2015)
PLoS Genet.
, vol.11
, pp. e1005504
-
-
Gralinski, L.E.1
-
58
-
-
84857969026
-
Sensing of RNA viruses: A review of innate immune receptors involved in recognizing RNA virus invasion
-
Jensen, S. & Thomsen, A. R. Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion. J. Virol. 86, 2900-2910 (2012).
-
(2012)
J. Virol.
, vol.86
, pp. 2900-2910
-
-
Jensen, S.1
Thomsen, A.R.2
-
59
-
-
77954066406
-
SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type i II and III interferon receptor independent mechanism
-
Frieman, M. B. et al. SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism. PLoS Pathog. 6, e1000849 (2010).
-
(2010)
PLoS Pathog.
, vol.6
, pp. e1000849
-
-
Frieman, M.B.1
-
60
-
-
58149234374
-
MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV
-
Sheahan, T. et al. MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV. PLoS Pathog. 4, e1000240 (2008).
-
(2008)
PLoS Pathog.
, vol.4
, pp. e1000240
-
-
Sheahan, T.1
-
61
-
-
84897480727
-
Rapid generation of a mouse model for Middle East respiratory syndrome
-
Zhao, J. et al. Rapid generation of a mouse model for Middle East respiratory syndrome. Proc. Natl Acad. Sci. USA 111 , 4970-4975 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 4970-4975
-
-
Zhao, J.1
-
62
-
-
84880177352
-
MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment
-
de Wilde, A. H. et al. MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment. J. Gen. Virol. 94, 1749-1760 (2013).
-
(2013)
J. Gen. Virol.
, vol.94
, pp. 1749-1760
-
-
De Wilde, A.H.1
-
63
-
-
33744928372
-
Ultrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complex
-
Snijder, E. J. et al. Ultrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complex. J. Virol. 80, 5927-5940 (2006).
-
(2006)
J. Virol.
, vol.80
, pp. 5927-5940
-
-
Snijder, E.J.1
-
64
-
-
77954053731
-
In vitro reconstitution of SARS-coronavirus mRNA cap methylation
-
Bouvet, M. et al. In vitro reconstitution of SARS-coronavirus mRNA cap methylation. PLoS Pathog. 6, e1000863 (2010).
-
(2010)
PLoS Pathog.
, vol.6
, pp. e1000863
-
-
Bouvet, M.1
-
65
-
-
84896981937
-
Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2′-O-methyltransferase activity
-
Menachery, V. D. et al. Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2′-O-methyltransferase activity. J. Virol. 88, 4251-4264 (2014).
-
(2014)
J. Virol.
, vol.88
, pp. 4251-4264
-
-
Menachery, V.D.1
-
66
-
-
84920574962
-
Coronavirus non-structural protein 16: Evasion, attenuation, and possible treatments
-
Menachery, V. D., Debbink, K. & Baric, R. S. Coronavirus non-structural protein 16: evasion, attenuation, and possible treatments. Virus Res. 194, 191-199 (2014).
-
(2014)
Virus Res.
, vol.194
, pp. 191-199
-
-
Menachery, V.D.1
Debbink, K.2
Baric, R.S.3
-
67
-
-
84938916581
-
The nucleocapsid protein of coronaviruses acts as a viral suppressor of RNA silencing in mammalian cells
-
Cui, L. et al. The nucleocapsid protein of coronaviruses acts as a viral suppressor of RNA silencing in mammalian cells. J. Virol. 89, 9029-9043 (2015).
-
(2015)
J. Virol.
, vol.89
, pp. 9029-9043
-
-
Cui, L.1
-
68
-
-
79960315021
-
SARS-CoV nucleocapsid protein antagonizes IFN-β response by targeting initial step of IFN-β induction pathway, and its C-terminal region is critical for the antagonism
-
Lu, X., Pan, J., Tao, J. & Guo, D. SARS-CoV nucleocapsid protein antagonizes IFN-β response by targeting initial step of IFN-β induction pathway, and its C-terminal region is critical for the antagonism. Virus Genes 42, 37-45 (2011).
-
(2011)
Virus Genes
, vol.42
, pp. 37-45
-
-
Lu, X.1
Pan, J.2
Tao, J.3
Guo, D.4
-
69
-
-
84886298565
-
Middle East respiratory syndrome coronavirus accessory protein 4a is a type i interferon antagonist
-
Niemeyer, D. et al. Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist. J. Virol. 87, 12489-12495 (2013).
-
(2013)
J. Virol.
, vol.87
, pp. 12489-12495
-
-
Niemeyer, D.1
-
70
-
-
84895534920
-
Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response
-
Siu, K. L. et al. Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response. J. Virol. 88, 4866-4876 (2014).
-
(2014)
J. Virol.
, vol.88
, pp. 4866-4876
-
-
Siu, K.L.1
-
71
-
-
84890049888
-
The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists
-
Yang, Y. et al. The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists. Protein Cell 4, 951-961 (2013).
-
(2013)
Protein Cell
, vol.4
, pp. 951-961
-
-
Yang, Y.1
-
72
-
-
84949257684
-
Middle East respiratory syndrome coronavirus ORF4b protein inhibits type i interferon production through both cytoplasmic and nuclear targets
-
Yang, Y. et al. Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets. Sci. Rep. 5, 17554 (2015).
-
(2015)
Sci. Rep.
, vol.5
, pp. 17554
-
-
Yang, Y.1
-
73
-
-
67449088510
-
Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-κB signaling
-
Frieman, M., Ratia, K., Johnston, R. E., Mesecar, A. D. & Baric, R. S. Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-κB signaling. J. Virol. 83, 6689-6705 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 6689-6705
-
-
Frieman, M.1
Ratia, K.2
Johnston, R.E.3
Mesecar, A.D.4
Baric, R.S.5
-
74
-
-
36148979683
-
Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus
-
Devaraj, S. G. et al. Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus. J. Biol. Chem. 282, 32208-32221 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 32208-32221
-
-
Devaraj, S.G.1
-
75
-
-
84938521107
-
The SARS coronavirus papain like protease can inhibit IRF3 at a post activation step that requires deubiquitination activity
-
Matthews, K., Schafer, A., Pham, A. & Frieman, M. The SARS coronavirus papain like protease can inhibit IRF3 at a post activation step that requires deubiquitination activity. Virol. J. 11 , 209 (2014).
-
(2014)
Virol. J.
, vol.11
, pp. 209
-
-
Matthews, K.1
Schafer, A.2
Pham, A.3
Frieman, M.4
-
76
-
-
84918528852
-
Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression
-
Bailey-Elkin, B. A. et al. Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression. J. Biol. Chem. 289, 34667-34682 (2014).
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 34667-34682
-
-
Bailey-Elkin, B.A.1
-
77
-
-
84855288589
-
SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: Viral mRNAs are resistant to nsp1-induced RNA cleavage
-
Huang, C. et al. SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage. PLoS Pathog. 7, e1002433 (2011).
-
(2011)
PLoS Pathog.
, vol.7
, pp. e1002433
-
-
Huang, C.1
-
78
-
-
70350768988
-
A two-pronged strategy to suppress host protein synthesis by SARS coronavirus nsp1 protein
-
Kamitani, W., Huang, C., Narayanan, K., Lokugamage, K. G. & Makino, S. A two-pronged strategy to suppress host protein synthesis by SARS coronavirus nsp1 protein. Nat. Struct. Mol. Biol. 16, 1134-1140 (2009).
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 1134-1140
-
-
Kamitani, W.1
Huang, C.2
Narayanan, K.3
Lokugamage, K.G.4
Makino, S.5
-
79
-
-
84869037184
-
Severe acute respiratory syndrome coronavirus nsp1 facilitates efficient propagation in cells through a specific translational shutoff of host mRNA
-
Tanaka, T. , Kamitani, W., DeDiego, M. L., Enjuanes, L. & Matsuura, Y. Severe acute respiratory syndrome coronavirus nsp1 facilitates efficient propagation in cells through a specific translational shutoff of host mRNA. J. Virol. 86, 11128-11137 (2012).
-
(2012)
J. Virol.
, vol.86
, pp. 11128-11137
-
-
Tanaka, T.1
Kamitani, W.2
DeDiego, M.L.3
Enjuanes, L.4
Matsuura, Y.5
-
80
-
-
35448939321
-
Severe acute respiratory syndrome coronavirus evades antiviral signaling: Role of nsp1 and rational design of an attenuated strain
-
Wathelet, M. G., Orr, M., Frieman, M. B. & Baric, R. S. Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain. J. Virol. 81, 11620-11633 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 11620-11633
-
-
Wathelet, M.G.1
Orr, M.2
Frieman, M.B.3
Baric, R.S.4
-
81
-
-
84945241899
-
Middle East respiratory syndrome coronavirus nsp1 inhibits host gene expression by selectively targeting mRNAs transcribed in the nucleus while sparing mRNAs of cytoplasmic origin
-
Lokugamage, K. G. et al. Middle East respiratory syndrome coronavirus nsp1 inhibits host gene expression by selectively targeting mRNAs transcribed in the nucleus while sparing mRNAs of cytoplasmic origin. J. Virol. 89, 10970-10981 (2015).
-
(2015)
J. Virol.
, vol.89
, pp. 10970-10981
-
-
Lokugamage, K.G.1
-
82
-
-
67449102609
-
Molecular determinants for subcellular localization of the severe acute respiratory syndrome coronavirus open reading frame 3b protein
-
Freundt, E. C., Yu, L., Park, E., Lenardo, M. J. & Xu, X. N. Molecular determinants for subcellular localization of the severe acute respiratory syndrome coronavirus open reading frame 3b protein. J. Virol. 83, 6631-6640 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 6631-6640
-
-
Freundt, E.C.1
Yu, L.2
Park, E.3
Lenardo, M.J.4
Xu, X.N.5
-
83
-
-
33846104528
-
Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b ORF 6 and nucleocapsid proteins function as interferon antagonists
-
Kopecky-Bromberg, S. A., Martinez-Sobrido, L., Frieman, M., Baric, R. A. & Palese, P. Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists. J. Virol. 81, 548-557 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 548-557
-
-
Kopecky-Bromberg, S.A.1
Martinez-Sobrido, L.2
Frieman, M.3
Baric, R.A.4
Palese, P.5
-
84
-
-
84875981860
-
MAVS-mediated apoptosis and its inhibition by viral proteins
-
Lei, Y. et al. MAVS-mediated apoptosis and its inhibition by viral proteins. PLoS ONE 4, e5466 (2009).
-
(2009)
PLoS ONE
, vol.4
, pp. e5466
-
-
Lei, Y.1
-
85
-
-
84904015653
-
Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses
-
Menachery, V. D. et al. Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses. mBio 5, e01174-14 (2014).
-
(2014)
MBio
, vol.5
, pp. e01174-e01214
-
-
Menachery, V.D.1
-
86
-
-
31144445870
-
Mechanisms of action of ribavirin against distinct viruses
-
Graci, J. D. & Cameron, C. E. Mechanisms of action of ribavirin against distinct viruses. Rev. Med. Virol. 16, 37-48 (2006).
-
(2006)
Rev. Med. Virol.
, vol.16
, pp. 37-48
-
-
Graci, J.D.1
Cameron, C.E.2
-
87
-
-
84896695450
-
Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: An observational study
-
Al-Tawfiq, J. A., Momattin, H., Dib, J. & Memish, Z. A. Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study. Int. J. Infect. Dis. 20, 42-46 (2014).
-
(2014)
Int. J. Infect. Dis.
, vol.20
, pp. 42-46
-
-
Al-Tawfiq, J.A.1
Momattin, H.2
Dib, J.3
Memish, Z.A.4
-
88
-
-
84947436351
-
Clinical analysis of the first patient with imported Middle East respiratory syndrome in China
-
Chinese
-
Ling, Y. , Qu, R. & Luo, Y. Clinical analysis of the first patient with imported Middle East respiratory syndrome in China. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 27, 630-634 (in Chinese) (2015).
-
(2015)
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
, vol.27
, pp. 630-634
-
-
Ling, Y.1
Qu, R.2
Luo, Y.3
-
89
-
-
0037976821
-
Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area
-
Booth, C. M. et al. Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area. JAMA 289, 2801-2809 (2003).
-
(2003)
JAMA
, vol.289
, pp. 2801-2809
-
-
Booth, C.M.1
-
90
-
-
0013165966
-
Identification of severe acute respiratory syndrome in Canada
-
Poutanen, S. M. et al. Identification of severe acute respiratory syndrome in Canada. N. Engl. J. Med. 348, 1995-2005 (2003).
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1995-2005
-
-
Poutanen, S.M.1
-
91
-
-
0038137600
-
Development of a standard treatment protocol for severe acute respiratory syndrome
-
So, L. K. et al. Development of a standard treatment protocol for severe acute respiratory syndrome. Lancet 361, 1615-1617 (2003).
-
(2003)
Lancet
, vol.361
, pp. 1615-1617
-
-
So, L.K.1
-
92
-
-
0013255608
-
A cluster of cases of severe acute respiratory syndrome in Hong Kong
-
Tsang, K. W. et al. A cluster of cases of severe acute respiratory syndrome in Hong Kong. N. Engl. J. Med. 348, 1977-1985 (2003).
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1977-1985
-
-
Tsang, K.W.1
-
93
-
-
0348136783
-
Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: A preliminary study
-
Loutfy, M. R. et al. Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study. JAMA 290, 3222-3228 (2003).
-
(2003)
JAMA
, vol.290
, pp. 3222-3228
-
-
Loutfy, M.R.1
-
94
-
-
0042354620
-
Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China
-
Zhao, Z. et al. Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China. J. Med. Microbiol. 52, 715-720 (2003).
-
(2003)
J. Med. Microbiol.
, vol.52
, pp. 715-720
-
-
Zhao, Z.1
-
95
-
-
0037783502
-
Severe acute respiratory syndrome (SARS) in Singapore: Clinical features of index patient and initial contacts
-
Hsu, L. Y. et al. Severe acute respiratory syndrome (SARS) in Singapore: clinical features of index patient and initial contacts. Emerg. Infect. Dis. 9, 713-717 (2003).
-
(2003)
Emerg. Infect. Dis.
, vol.9
, pp. 713-717
-
-
Hsu, L.Y.1
-
96
-
-
84883438898
-
Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: Evidence for proofreading and potential therapeutics
-
Smith, E. C., Blanc, H., Surdel, M. C., Vignuzzi, M. & Denison, M. R. Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics. PLoS Pathog. 9, e1003565 (2013).
-
(2013)
PLoS Pathog.
, vol.9
, pp. e1003565
-
-
Smith, E.C.1
Blanc, H.2
Surdel, M.C.3
Vignuzzi, M.4
Denison, M.R.5
-
97
-
-
84887019388
-
Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus
-
Chan, J. F. et al. Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus. J. Infect. 67, 606-616 (2013).
-
(2013)
J. Infect.
, vol.67
, pp. 606-616
-
-
Chan, J.F.1
-
98
-
-
84879840922
-
Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin
-
Falzarano, D. et al. Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin. Sci. Rep. 3, 1686 (2013).
-
(2013)
Sci. Rep.
, vol.3
, pp. 1686
-
-
Falzarano, D.1
-
99
-
-
84894028391
-
Interferon-β and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays
-
Hart, B. J. et al. Interferon-β and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays. J. Gen. Virol. 95, 571-577 (2014).
-
(2014)
J. Gen. Virol.
, vol.95
, pp. 571-577
-
-
Hart, B.J.1
-
100
-
-
10644274503
-
Ribavirin and interferon-β synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines
-
Morgenstern, B., Michaelis, M., Baer, P. C., Doerr, H. W. & Cinatl, J. Ribavirin and interferon-β synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines. Biochem. Biophys. Res. Commun. 326, 905-908 (2005).
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.326
, pp. 905-908
-
-
Morgenstern, B.1
Michaelis, M.2
Baer, P.C.3
Doerr, H.W.4
Cinatl, J.5
-
101
-
-
84887492222
-
Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques
-
Falzarano, D. et al. Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques. Nat. Med. 19, 1313-1317 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 1313-1317
-
-
Falzarano, D.1
-
102
-
-
84908285527
-
Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: A retrospective cohort study
-
Omrani, A. S. et al. Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study. Lancet Infect. Dis. 14, 1090-1095 (2014).
-
(2014)
Lancet Infect. Dis.
, vol.14
, pp. 1090-1095
-
-
Omrani, A.S.1
-
103
-
-
84936931504
-
IFN-α2a or IFN-β1a in combination with ribavirin to treat Middle East respiratory syndrome coronavirus pneumonia: A retrospective study
-
Shalhoub, S. et al. IFN-α2a or IFN-β1a in combination with ribavirin to treat Middle East respiratory syndrome coronavirus pneumonia: a retrospective study. J. Antimicrob. Chemother. 70, 2129-2132 (2015).
-
(2015)
J. Antimicrob. Chemother.
, vol.70
, pp. 2129-2132
-
-
Shalhoub, S.1
-
104
-
-
84927749252
-
Ribavirin and interferon-α2b as primary and preventive treatment for Middle East respiratory syndrome coronavirus: A preliminary report of two cases
-
Khalid, M. et al. Ribavirin and interferon-α2b as primary and preventive treatment for Middle East respiratory syndrome coronavirus: a preliminary report of two cases. Antivir. Ther. 20, 87-91 (2015).
-
(2015)
Antivir. Ther.
, vol.20
, pp. 87-91
-
-
Khalid, M.1
-
105
-
-
84955391557
-
Treatment with lopinavir/ritonavir or interferon-β1b improves outcome of MERS-CoV infection in a non-human primate model of common marmoset
-
Chan, J. F. et al. Treatment with lopinavir/ritonavir or interferon-β1b improves outcome of MERS-CoV infection in a non-human primate model of common marmoset. J. Infect. Dis. 212, 1904-1913 (2015).
-
(2015)
J. Infect. Dis.
, vol.212
, pp. 1904-1913
-
-
Chan, J.F.1
-
106
-
-
10744223243
-
Treatment of severe acute respiratory syndrome with lopinavir/ritonavir: A multicentre retrospective matched cohort study
-
Chan, K. S. et al. Treatment of severe acute respiratory syndrome with lopinavir/ritonavir: a multicentre retrospective matched cohort study. Hong Kong Med. J. 9, 399-406 (2003).
-
(2003)
Hong Kong Med. J.
, vol.9
, pp. 399-406
-
-
Chan, K.S.1
-
107
-
-
12144290587
-
Role of lopinavir/ritonavir in the treatment of SARS: Initial virological and clinical findings
-
Chu, C. M. et al. Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings. Thorax 59, 252-256 (2004).
-
(2004)
Thorax
, vol.59
, pp. 252-256
-
-
Chu, C.M.1
-
108
-
-
84911945010
-
Virological and serological analysis of a recent Middle East respiratory syndrome coronavirus infection case on a triple combination antiviral regimen
-
Spanakis, N. et al. Virological and serological analysis of a recent Middle East respiratory syndrome coronavirus infection case on a triple combination antiviral regimen. Int. J. Antimicrob. Agents 44, 528-532 (2014).
-
(2014)
Int. J. Antimicrob. Agents
, vol.44
, pp. 528-532
-
-
Spanakis, N.1
-
109
-
-
84964432678
-
Middle East respiratory syndrome-coronavirus infection: A case report of serial computed tomographic findings in a young male patient
-
Choi, W. J., Lee, K. N., Kang, E. J. & Lee, H. Middle East respiratory syndrome-coronavirus infection: a case report of serial computed tomographic findings in a young male patient. Korean J. Radiol 17, 166-170 (2016).
-
(2016)
Korean J. Radiol
, vol.17
, pp. 166-170
-
-
Choi, W.J.1
Lee, K.N.2
Kang, E.J.3
Lee, H.4
-
110
-
-
84991434329
-
Combination therapy with lopinavir/ ritonavir, ribavirin and interferon-α for Middle East respiratory syndrome: A case report
-
Kim, U. J., Won, E. J., Kee, S. J., Jung, S. I. & Jang, H. C. Combination therapy with lopinavir/ ritonavir, ribavirin and interferon-α for Middle East respiratory syndrome: a case report. Antivir. Ther. http://dx.doi.org/10.3851/IMP3002 (2015).
-
(2015)
Antivir. Ther.
-
-
Kim, U.J.1
Won, E.J.2
Kee, S.J.3
Jung, S.I.4
Jang, H.C.5
-
111
-
-
84988040398
-
Clinical implications of five cases of Middle East respiratory syndrome coronavirus infection in South Korea Outbreak
-
Rhee, J. Y., Hong, G. & Ryu, K. M. Clinical implications of five cases of Middle East respiratory syndrome coronavirus infection in South Korea Outbreak. Jpn J. Infect. Dis. http://dx.doi.org/10.7883/yoken. JJID.2015.445 (2016).
-
(2016)
Jpn J. Infect. Dis.
-
-
Rhee, J.Y.1
Hong, G.2
Ryu, K.M.3
-
112
-
-
84908867742
-
From SARS to MERS: Crystallographic studies on coronaviral proteases enable antiviral drug design
-
Hilgenfeld, R. From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design. FEBS J. 281, 4085-4096 (2014).
-
(2014)
FEBS J.
, vol.281
, pp. 4085-4096
-
-
Hilgenfeld, R.1
-
113
-
-
84920260798
-
Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus
-
Cheng, K. W. et al. Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus. Antiviral Res. 11 5 , 9-16 (2015).
-
(2015)
Antiviral Res.
, vol.11
, Issue.5
, pp. 9-16
-
-
Cheng, K.W.1
-
114
-
-
84939231634
-
pro): Implications for nsp5 regulation and the development of antivirals
-
pro): implications for nsp5 regulation and the development of antivirals. J. Biol. Chem. 290, 19403-19422 (2015).
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 19403-19422
-
-
Tomar, S.1
-
115
-
-
84905386648
-
Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture
-
de Wilde, A. H. et al. Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture. Antimicrob. Agents Chemother. 58, 4875-4884 (2014).
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 4875-4884
-
-
De Wilde, A.H.1
-
116
-
-
84978362736
-
Treatment of MERS-CoV: Decision support tool
-
updated 29 July 2013
-
International Severe Acute Respiratory & Emerging Infection Consortium. Treatment of MERS-CoV: decision support tool. International Severe Acute Respiratory & Emerging Infection Consortium, https:// isaric.tghn.org/site-media/media/articles/Decision- Support-Document-v1-1-20130729.pdf (updated 29 July 2013).
-
International Severe Acute Respiratory & Emerging Infection Consortium
-
-
-
117
-
-
84922440585
-
The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: A systematic review and exploratory meta-analysis
-
Mair-Jenkins, J. et al. The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis. J. Infect. Dis. 2 11 , 80-90 (2015).
-
(2015)
J. Infect. Dis.
, vol.2
, Issue.11
, pp. 80-90
-
-
Mair-Jenkins, J.1
-
118
-
-
84901303550
-
A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein
-
Du, L. et al. A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein. J. Virol. 88, 7045-7053 (2014).
-
(2014)
J. Virol.
, vol.88
, pp. 7045-7053
-
-
Du, L.1
-
119
-
-
84899797757
-
Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein
-
Jiang, L. et al. Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein. Sci. Transl Med. 6, 234ra59 (2014).
-
(2014)
Sci. Transl Med.
, vol.6
, pp. 234ra59
-
-
Jiang, L.1
-
120
-
-
84900515662
-
Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution
-
Tang, X. C. et al. Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution. Proc. Natl Acad. Sci. USA 111 , E2018-E2026 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. E2018-E2026
-
-
Tang, X.C.1
-
121
-
-
84904663317
-
Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies
-
Ying, T. et al. Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies. J. Virol. 88, 7796-7805 (2014).
-
(2014)
J. Virol.
, vol.88
, pp. 7796-7805
-
-
Ying, T.1
-
122
-
-
84929619188
-
Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection
-
Zhao, J. et al. Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection. J. Virol. 89, 6117-6120 (2015).
-
(2015)
J. Virol.
, vol.89
, pp. 6117-6120
-
-
Zhao, J.1
-
123
-
-
84973153410
-
Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo
-
Luke, T. et al. Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo. Sci. Transl Med. 8, 326ra21 (2016).
-
(2016)
Sci. Transl Med.
, vol.8
, pp. 326ra21
-
-
Luke, T.1
-
124
-
-
84946491594
-
A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein
-
Li, Y. et al. A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein. Cell Res. 25, 1237-1249 (2015).
-
(2015)
Cell Res.
, vol.25
, pp. 1237-1249
-
-
Li, Y.1
-
125
-
-
84939863145
-
Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
-
Corti, D. et al. Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus. Proc. Natl Acad. Sci. USA 11 2 , 10473-10478 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.11
, Issue.2
, pp. 10473-10478
-
-
Corti, D.1
-
126
-
-
84937107017
-
Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection
-
Pascal, K. E. et al. Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection. Proc. Natl Acad. Sci. USA 11 2 , 8738-8743 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.11
, Issue.2
, pp. 8738-8743
-
-
Pascal, K.E.1
-
127
-
-
84970027977
-
Prophylaxis with a MERS-CoV-specific human monoclonal antibody protects rabbits from MERS-CoV infection
-
Houser, K. V. et al. Prophylaxis with a MERS-CoV-specific human monoclonal antibody protects rabbits from MERS-CoV infection. J. Infect. Dis. 213, 1557-1561 (2016).
-
(2016)
J. Infect. Dis.
, vol.213
, pp. 1557-1561
-
-
Houser, K.V.1
-
128
-
-
84961381392
-
3B11-N a monoclonal antibody against MERS-CoV reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012
-
Johnson, R. F. et al. 3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012. Virology 490, 49-58 (2016).
-
(2016)
Virology
, vol.490
, pp. 49-58
-
-
Johnson, R.F.1
-
129
-
-
84888037046
-
Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody
-
Ohnuma, K. et al. Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody. J. Virol. 87, 13892-13899 (2013).
-
(2013)
J. Virol.
, vol.87
, pp. 13892-13899
-
-
Ohnuma, K.1
-
130
-
-
84896904424
-
Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola Hendra and Nipah viruses by using a novel high-throughput screening assay
-
Elshabrawy, H. A. et al. Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assay. J. Virol. 88, 4353-4365 (2014).
-
(2014)
J. Virol.
, vol.88
, pp. 4353-4365
-
-
Elshabrawy, H.A.1
-
131
-
-
79954628266
-
Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response
-
Glowacka, I. et al. Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response. J. Virol. 85, 4122-4134 (2011).
-
(2011)
J. Virol.
, vol.85
, pp. 4122-4134
-
-
Glowacka, I.1
-
132
-
-
84923219776
-
Protease inhibitors targeting coronavirus and filovirus entry
-
Zhou, Y. et al. Protease inhibitors targeting coronavirus and filovirus entry. Antiviral Res. 11 6 , 76-84 (2015).
-
(2015)
Antiviral Res.
, vol.11
, Issue.6
, pp. 76-84
-
-
Zhou, Y.1
-
133
-
-
84928879766
-
The role of C5a in acute lung injury induced by highly pathogenic viral infections
-
Wang, R., Xiao, H., Guo, R., Li, Y. & Shen, B. The role of C5a in acute lung injury induced by highly pathogenic viral infections. Emerg. Microbes Infect. 4, e28 (2015).
-
(2015)
Emerg. Microbes Infect.
, vol.4
, pp. e28
-
-
Wang, R.1
Xiao, H.2
Guo, R.3
Li, Y.4
Shen, B.5
-
134
-
-
84879571351
-
Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus
-
Josset, L. et al. Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus. mBio 4, e00165-13 (2013).
-
(2013)
MBio
, vol.4
, pp. e00165-e00213
-
-
Josset, L.1
-
135
-
-
84888011629
-
A decade after SARS: Strategies for controlling emerging coronaviruses
-
Graham, R. L., Donaldson, E. F. & Baric, R. S. A decade after SARS: strategies for controlling emerging coronaviruses. Nat. Rev. Microbiol. 11 , 836-848 (2013).
-
(2013)
Nat. Rev. Microbiol.
, vol.11
, pp. 836-848
-
-
Graham, R.L.1
Donaldson, E.F.2
Baric, R.S.3
-
136
-
-
67650462880
-
SARS vaccines: Where are we?
-
Roper, R. L. & Rehm, K. E. SARS vaccines: where are we? Expert Rev. Vaccines 8, 887-898 (2009).
-
(2009)
Expert Rev Vaccines
, vol.8
, pp. 887-898
-
-
Roper, R.L.1
Rehm, K.E.2
-
137
-
-
84946495956
-
Middle East respiratory syndrome: Current status and future prospects for vaccine development
-
Du, L. & Jiang, S. Middle East respiratory syndrome: current status and future prospects for vaccine development. Expert Opin. Biol. Ther. 15, 1647-1651 (2015).
-
(2015)
Expert Opin. Biol. Ther.
, vol.15
, pp. 1647-1651
-
-
Du, L.1
Jiang, S.2
-
138
-
-
84938149041
-
Evaluation of candidate vaccine approaches for MERS-CoV
-
Wang, L. et al. Evaluation of candidate vaccine approaches for MERS-CoV. Nat. Commun. 6, 7712 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 7712
-
-
Wang, L.1
-
139
-
-
84951906168
-
Recombinant receptor binding domain protein induces partial protective immunity in rhesus macaques against Middle East respiratory syndrome coronavirus challenge
-
Lan, J. et al. Recombinant receptor binding domain protein induces partial protective immunity in rhesus macaques against Middle East respiratory syndrome coronavirus challenge. EBioMedicine 2, 1438-1446 (2015).
-
(2015)
EBioMedicine
, vol.2
, pp. 1438-1446
-
-
Lan, J.1
-
140
-
-
84939810764
-
A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates
-
Muthumani, K. et al. A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates. Sci. Transl Med. 7, 301ra132 (2015).
-
(2015)
Sci. Transl Med.
, vol.7
, pp. 301ra132
-
-
Muthumani, K.1
-
141
-
-
84912003579
-
Immune efficacy of first and repeat trivalent influenza vaccine in healthy subjects and hemodialysis patients
-
Mastalerz-Migas, A., Bujnowska-Fedak, M. & Brydak, L. B. Immune efficacy of first and repeat trivalent influenza vaccine in healthy subjects and hemodialysis patients. Adv. Exp. Med. Biol. 836, 47-54 (2015).
-
(2015)
Adv. Exp. Med. Biol.
, vol.836
, pp. 47-54
-
-
Mastalerz-Migas, A.1
Bujnowska-Fedak, M.2
Brydak, L.B.3
-
142
-
-
84928213277
-
Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: A nationwide, cross-sectional, serological study
-
Muller, M. A. et al. Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study. Lancet Infect. Dis. 15, 629 (2015).
-
(2015)
Lancet Infect. Dis.
, vol.15
, pp. 629
-
-
Muller, M.A.1
-
143
-
-
84952932413
-
An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels
-
Haagmans, B. L. et al. An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels. Science 351, 77-81 (2016).
-
(2016)
Science
, vol.351
, pp. 77-81
-
-
Haagmans, B.L.1
-
144
-
-
84882598788
-
Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: A descriptive study
-
Assiri, A. et al. Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect. Dis. 13, 752-761 (2013).
-
(2013)
Lancet Infect. Dis.
, vol.13
, pp. 752-761
-
-
Assiri, A.1
-
145
-
-
3242687609
-
The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: An analysis of all 1755 patients
-
Leung, G. M. et al. The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: an analysis of all 1755 patients. Ann. Intern. Med. 141, 662-673 (2004).
-
(2004)
Ann. Intern. Med.
, vol.141
, pp. 662-673
-
-
Leung, G.M.1
-
146
-
-
84941413167
-
Middle East respiratory syndrome
-
Zumla, A., Hui, D. S. & Perlman, S. Middle East respiratory syndrome. Lancet 386, 995-1007 (2015).
-
(2015)
Lancet
, vol.386
, pp. 995-1007
-
-
Zumla, A.1
Hui, D.S.2
Perlman, S.3
-
147
-
-
84906939065
-
Hospital-associated outbreak of Middle East respiratory syndrome coronavirus: A serologic, epidemiologic, and clinical description
-
Al-Abdallat, M. M. et al. Hospital-associated outbreak of Middle East respiratory syndrome coronavirus: a serologic, epidemiologic, and clinical description. Clin. Infect. Dis. 59, 1225-1233 (2014).
-
(2014)
Clin. Infect. Dis.
, vol.59
, pp. 1225-1233
-
-
Al-Abdallat, M.M.1
-
148
-
-
84916891516
-
Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: A single-center experience in Saudi Arabia
-
Saad, M. et al. Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia. Int. J. Infect. Dis. 29, 301-306 (2014).
-
(2014)
Int. J. Infect. Dis.
, vol.29
, pp. 301-306
-
-
Saad, M.1
-
149
-
-
84901422841
-
Respiratory tract samples, viral load, and genome fraction yield in patients with Middle East respiratory syndrome
-
Memish, Z. A. et al. Respiratory tract samples, viral load, and genome fraction yield in patients with Middle East respiratory syndrome. J. Infect. Dis. 210, 1590-1594 (2014).
-
(2014)
J. Infect. Dis.
, vol.210
, pp. 1590-1594
-
-
Memish, Z.A.1
-
150
-
-
84944556317
-
Association of higher MERS-CoV virus load with severe disease and death, Saudi Arabia, 2014
-
Feikin, D. R. et al. Association of higher MERS-CoV virus load with severe disease and death, Saudi Arabia, 2014. Emerg. Infect. Dis. 21, 2029-2035 (2015).
-
(2015)
Emerg. Infect. Dis.
, vol.21
, pp. 2029-2035
-
-
Feikin, D.R.1
-
151
-
-
84944586565
-
Mortality risk factors for Middle East respiratory syndrome outbreak, South Korea, 2015
-
Majumder, M. S., Kluberg, S. A., Mekaru, S. R. & Brownstein, J. S. Mortality risk factors for Middle East respiratory syndrome outbreak, South Korea, 2015. Emerg. Infect. Dis. 21, 2088-2090 (2015).
-
(2015)
Emerg. Infect. Dis.
, vol.21
, pp. 2088-2090
-
-
Majumder, M.S.1
Kluberg, S.A.2
Mekaru, S.R.3
Brownstein, J.S.4
-
152
-
-
84937555298
-
Animal models for SARS and MERS coronaviruses
-
Gretebeck, L. M. & Subbarao, K. Animal models for SARS and MERS coronaviruses. Curr. Opin. Virol. 13, 123-129 (2015).
-
(2015)
Curr. Opin. Virol.
, vol.13
, pp. 123-129
-
-
Gretebeck, L.M.1
Subbarao, K.2
-
153
-
-
84959017698
-
Replication and shedding of MERS-CoV in Jamaican fruit bats (Artibeus jamaicensis)
-
Munster, V. J. et al. Replication and shedding of MERS-CoV in Jamaican fruit bats (Artibeus jamaicensis). Sci. Rep. 6, 21878 (2016).
-
(2016)
Sci. Rep.
, vol.6
, pp. 21878
-
-
Munster, V.J.1
-
154
-
-
25444531712
-
Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats
-
Lau, S. K. et al. Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. Proc. Natl Acad. Sci. USA 102, 14040-14045 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 14040-14045
-
-
Lau, S.K.1
-
155
-
-
27344438916
-
Bats are natural reservoirs of SARS-like coronaviruses
-
Li, W. et al. Bats are natural reservoirs of SARS-like coronaviruses. Science 310, 676-679 (2005).
-
(2005)
Science
, vol.310
, pp. 676-679
-
-
Li, W.1
-
156
-
-
13444282371
-
Civets are equally susceptible to experimental infection by two different severe acute respiratory syndrome coronavirus isolates
-
Wu, D. et al. Civets are equally susceptible to experimental infection by two different severe acute respiratory syndrome coronavirus isolates. J. Virol. 79, 2620-2625 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 2620-2625
-
-
Wu, D.1
-
157
-
-
84922417105
-
Replication and shedding of MERS-CoV in upper respiratory tract of inoculated dromedary camels
-
Adney, D. R. et al. Replication and shedding of MERS-CoV in upper respiratory tract of inoculated dromedary camels. Emerg. Infect. Dis. 20, 1999-2005 (2014).
-
(2014)
Emerg. Infect. Dis.
, vol.20
, pp. 1999-2005
-
-
Adney, D.R.1
-
158
-
-
58149398620
-
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice
-
Becker, M. M. et al. Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc. Natl Acad. Sci. USA 105, 19944-19949 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 19944-19949
-
-
Becker, M.M.1
-
159
-
-
84962487236
-
SARS-like WIV1-CoV poised for human emergence
-
Menachery, V. D. et al. SARS-like WIV1-CoV poised for human emergence. Proc. Natl Acad. Sci. USA 11 3 , 3048-3053 (2016).
-
(2016)
Proc. Natl Acad. Sci. USA
, vol.11
, Issue.3
, pp. 3048-3053
-
-
Menachery, V.D.1
|