SARS-like WIV1-CoV poised for human emergence

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 11, 2016, Pages 3048-3053

  Menachery, Vineet D ^a   Yount, Boyd L ^a   Sims, Amy C ^a   Debbink, Kari ^a,b   Agnihothram, Sudhakar S ^c   Gralinski, Lisa E ^a   Graham, Rachel L ^a   Scobey, Trevor ^a   Plante, Jessica A ^a   Royal, Scott R ^a   Swanstrom, Jesica ^a   Sheahan, Timothy P ^a   Pickles, Raymond J ^b,c   Corti, Davide ^d,e,f   Randell, Scott H ^b   Lanzavecchia, Antonio ^d,e   Marasco, Wayne A ^g   Baric, Ralph S ^a,c  

^a IL   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^d INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Switzerland)

^e ETH ZURICH   (Switzerland)

^f Harvard Medical School ^*  (Switzerland)

^g HARVARD MEDICAL SCHOOL   (United States)

Author keywords

CoV; Emergence; SARS; Spike; WIV1

Indexed keywords

MONOCLONAL ANTIBODY; REAGENT; ANGIOTENSIN CONVERTING ENZYME 2; CORONAVIRUS SPIKE GLYCOPROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE; HYBRID PROTEIN; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY; VIRUS RECEPTOR;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; CORONAVIRIDAE; EPIDEMIC; EPITHELIUM CELL; HUMAN; HUMAN CELL; METAGENOMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE GENETICS; SEVERE ACUTE RESPIRATORY SYNDROME; VACCINATION; VIRION; VIRUS STRAIN; VIRUS TRANSMISSION; WIV1 CORONAVIRUS; ANIMAL; BAGG ALBINO MOUSE; BAT; CELL CULTURE; CHLOROCEBUS AETHIOPS; COMMUNICABLE DISEASE; COMPARATIVE STUDY; CORONAVIRIDAE INFECTIONS; CROSS REACTION; CYTOLOGY; GENETICS; HOST RANGE; IMMUNOLOGY; ISOLATION AND PURIFICATION; LUNG; METABOLISM; MOLECULAR MODEL; PATHOGENICITY; PHYSIOLOGY; POINT MUTATION; PROTEIN CONFORMATION; SARS CORONAVIRUS; SPECIES DIFFERENCE; TRANSGENIC MOUSE; TRANSMISSION; VERO CELL LINE; VETERINARY; VIROLOGY; VIRUS ENCEPHALITIS; VIRUS REPLICATION; ZOONOSIS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CHIROPTERA; COMMUNICABLE DISEASES, EMERGING; CORONAVIRIDAE; CORONAVIRIDAE INFECTIONS; CROSS REACTIONS; ENCEPHALITIS, VIRAL; EPITHELIAL CELLS; HOST SPECIFICITY; HUMANS; LUNG; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MODELS, MOLECULAR; PEPTIDYL-DIPEPTIDASE A; POINT MUTATION; PROTEIN CONFORMATION; RECEPTORS, VIRUS; RECOMBINANT FUSION PROTEINS; SARS VIRUS; SPECIES SPECIFICITY; SPIKE GLYCOPROTEIN, CORONAVIRUS; VERO CELLS; VIRUS REPLICATION; ZOONOSES;

EID: 84962487236     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1517719113     Document Type: Article

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