Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity

Journal of Virology

Volumn 88, Issue 8, 2014, Pages 4251-4264

  Menachery, Vineet D ^a   Yount, Boyd L ^a   Josset, Laurence ^c   Gralinski, Lisa E ^a   Scobey, Trevor ^a   Agnihothram, Sudhakar ^a   Katze, Michael G ^c,d   Baric, Ralph S ^a,b  

^a IL   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2' O METHYLTRANSFERASE; IFIT PROTEIN; INTERFERON; MDA5 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; VIRUS ENZYME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONAVIRUS INFECTION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; SARS CORONAVIRUS; SENSITIVITY ANALYSIS; VIRAL PHENOMENA AND FUNCTIONS; VIRAL RESTORATION; VIRUS ATTENUATION; VIRUS MUTANT; VIRUS REPLICATION; VIRUS VIRULENCE; WEIGHT REDUCTION;

AMINO ACID MOTIFS; ANIMALS; CARRIER PROTEINS; DEAD-BOX RNA HELICASES; FEMALE; HUMANS; MALE; METHYLTRANSFERASES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MUTATION; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; VIRAL NONSTRUCTURAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

EID: 84896981937     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03571-13     Document Type: Article

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