Rapid generation of a mouse model for Middle East respiratory syndrome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 13, 2014, Pages 4970-4975

  Zhao, Jincun ^a   Li, Kun ^b   Wohlford Lenane, Christine ^b   Agnihothram, Sudhakar S ^c   Fett, Craig ^a   Zhao, Jingxian ^a   Gale Jr , Michael J ^d   Baric, Ralph S ^c   Enjuanes, Luis ^e   Gallagher, Tom ^f   McCray Jr , Paul B ^b   Perlman, Stanley ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^e CSIC   (Spain)

^f LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Emerging pathogen; Interferon; Sars

Indexed keywords

ADENOVIRUS VECTOR; DIPEPTIDYL PEPTIDASE IV; INTERFERON; MERS COV SPIKE PROTEIN; POLYINOSINIC POLYCYTIDYLIC ACID; SEVERE ACUTE RESPIRATORY SYNDROME VACCINE; UNCLASSIFIED DRUG; VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONAVIRUS INFECTION; CROSS REACTION; DISEASE SEVERITY; DRUG EFFICACY; GENE INDUCTION; HISTOPATHOLOGY; INFLAMMATORY INFILTRATE; LUNG INFILTRATE; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS INFECTION; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; REPLICON; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VENEZUELAN EQUINE ENCEPHALITIS; VIRAL CLEARANCE; VIRUS IMMUNITY; VIRUS PNEUMONIA;

EMERGING PATHOGEN; INTERFERON; SARS;

ANIMALS; ANTIBODIES, VIRAL; CD8-POSITIVE T-LYMPHOCYTES; CORONAVIRUS; CORONAVIRUS INFECTIONS; CROSS REACTIONS; DISEASE MODELS, ANIMAL; HUMANS; INTERFERON TYPE I; MICE; MICE, INBRED C57BL; MIDDLE EAST; RESPIRATORY TRACT INFECTIONS; SEVERE ACUTE RESPIRATORY SYNDROME; SIGNAL TRANSDUCTION;

EID: 84897480727     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1323279111     Document Type: Article

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