Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: A prospective study

Lancet

Volumn 361, Issue 9371, 2003, Pages 1767-1772

  Peiris, J S M ^a   Chu, C M ^b   Cheng, V C C ^a   Chan, K S ^b   Hung, I F N ^a   Poon, L L M ^a   Law, K I ^b   Tang, B S F ^a   Hon, T Y W ^b   Chan, C S ^b   Chan, K H ^a   Ng, J S C ^b   Zheng, B J ^a   Ng, W L ^b   Lai, R W M ^b   Guan, Y ^a   Yuen, K Y ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNITED CHRISTIAN HOSPITAL   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AZITHROMYCIN; CORTICOSTEROID; HYDROCORTISONE; LAMIVUDINE; LEVOFLOXACIN; MEPREDNISONE; PREDNISOLONE; RIBAVIRIN;

ADULT; ARTICLE; ASPIRATION; CLINICAL FEATURE; CLINICAL TRIAL; CORONAVIRUS; DIAGNOSTIC PROCEDURE; DISEASE ASSOCIATION; DISEASE COURSE; EPIDEMIC; FEMALE; FEVER; FOLLOW UP; HEPATITIS B; HOSPITAL ADMISSION; HUMAN; IMMUNOPATHOLOGY; LUNG INJURY; MAJOR CLINICAL STUDY; MALE; PATIENT CARE; PNEUMOMEDIASTINUM; PNEUMONIA; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; RADIOLOGICAL PROCEDURES; RECURRENT DISEASE; RESPIRATORY DISTRESS; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; SEROCONVERSION; SEVERE ACUTE RESPIRATORY SYNDROME; TREATMENT OUTCOME; VERNER MORRISON SYNDROME; VIRUS LOAD; VIRUS REPLICATION;

EID: 0038362701     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(03)13412-5     Document Type: Article

References (18)

1. Severe Acute Respiratory Syndrome (SARS): multi-country outbreak - update 34. http://www.who.int/csr/don/2003_04_19/en/ (accessed May 5, 2003).
2. Centers for Disease Control and Prevention. SARS coronavirus sequencing. http://www.cdc.gov/ncidod/sars/sequence.htm (accessed May 5, 2003).
3. Peiris J.S.M., Lai S.T., Poon L.L.M., et al. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet. 361:2003;1319-1325.
4. Ksiazek TG, Erdman D, Goldsmith CS, et al. A novel coronavirus associated with severe acute respiratory syndrome. http://content.nejm.org/cgi/reprint/NEJMoa030781v3.pdf (accessed at May 5, 2003).
5. Poutanen SM, Low DE, Henry B, et al. Identification of severe acute respiratory syndrome in Canada. http://content.nejm.org/cgi/reprint/NEJMoa030634v3.pdf (accessed May 5, 2003).
6. Lee N, Hui D, Wu A, et al. A major outbreak of severe acute respiratory syndrome in Hong Kong. http://content.nejm.org/cgi/reprint/NEJMoa030685v2.pdf (accessed May 5, 2003).
7. Tsang KW, Ho PL, Ooi GC, et al. A cluster of cases of severe acute respiratory syndrome in Hong Kong. http://content.nejm.org/cgi/reprint/NEJMoa030666v3.pdf (accessed May 5, 2003).
8. Atypical pneumonia. http://www.info.gov.hk/dh/ap.htm (accessed May 5, 2003).
9. Ho W. Guideline on management of severe acute respiratory syndrome (SARS). Lancet. 361:2003;1313-1315.
10. HA guidelines on severe acute respiratory syndrome. http://www.ha.org.hk/sars/guidelines/index.html (accessed May 5, 2003).
11. Bernard G.R., Artigas A., Brigham K.L., et al. The American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med. 149:1994;818-824.
12. Knaus W.A., Draper E.A., Wagner D.P., et al. APACHE II: a severity of disease classification system. Crit Care Med. 13:1985;818-829.
13. Poon LLM, Wong OK, Luk W, et al. Rapid diagnosis of a coronavirus associated with severe acute respiratory syndrome (SARS). http://www.clinchem.org/cgi/content/full/49/4/DC1 (accessed May 5, 2003).
14. Majeski E.I., Harley R.A., Bellum S.C., et al. Differential role for T cells in the development of fibrotic lesions associated with reovirus 1/L-induced bronchiolitis obliterans organizing pneumonia versus acute respiratory distress syndrome. Am J Respir Cell Mol Biol. 28:2003;208-217.
15. Ning Q., Brown D., Parodo J., et al. Ribavirin inhibits viral-induced macrophage production of TNF, IL-1, the procoagulant fgl2 prothrombinase and preserves Th1 cytokine production but inhibits Th2 cytokine response. J Immunol. 160:1998;3487-3493.
16. Turner R.B., Felton A., Kosak K., et al. Prevention of experimental coronavirus colds with intranasal alpha-2b interferon. J Infect Dis. 154:1986;443-447.
17. Olliff J.F., Williams M.P. Radiological appearances of cytomegalovirus infections. Clin Radiol. 40:1989;463-467.
18. Tutor J.D., Montgomery V.L., Eid N.S. A case of influenza bronchiolitis complicated by pneumomediastinum and subcutaneous emphysema. Pediatr Pulmonol. 19:1995;393-395.