-
3
-
-
84882598788
-
Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: A descriptive study
-
Assiri, A. et al. Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect. Dis. 13, 752-761 (2013).
-
(2013)
Lancet Infect. Dis.
, vol.13
, pp. 752-761
-
-
Assiri, A.1
-
4
-
-
84882918127
-
Interhuman transmissibility of Middle East respiratory syndrome coronavirus: Estimation of pandemic risk
-
Breban, R., Riou, J. & Fontanet, A. Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk. Lancet 382, 694-699 (2013).
-
(2013)
Lancet
, vol.382
, pp. 694-699
-
-
Breban, R.1
Riou, J.2
Fontanet, A.3
-
5
-
-
84890433761
-
Middle East respiratory syndrome coronavirus: Quantification of the extent of the epidemic, surveillance biases, and transmissibility
-
Cauchemez, S. et al. Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility. Lancet Infect. Dis. 14, 50-56 (2014).
-
(2014)
Lancet Infect. Dis.
, vol.14
, pp. 50-56
-
-
Cauchemez, S.1
-
6
-
-
84899938536
-
Human infection with MERS coronavirus after exposure to infected camels, Saudi Arabia, 2013
-
Memish, Z. A. et al. Human infection with MERS coronavirus after exposure to infected camels, Saudi Arabia, 2013. Emerg. Infect. Dis. 20, 1012-1015 (2014).
-
(2014)
Emerg. Infect. Dis.
, vol.20
, pp. 1012-1015
-
-
Memish, Z.A.1
-
7
-
-
84888011629
-
A decade after SARS: Strategies for controlling emerging coronaviruses
-
Graham, R. L., Donaldson, E. F. & Baric, R. S. A decade after SARS: strategies for controlling emerging coronaviruses. Nat. Rev. Microbiol. 11, 836-848 (2013).
-
(2013)
Nat. Rev. Microbiol.
, vol.11
, pp. 836-848
-
-
Graham, R.L.1
Donaldson, E.F.2
Baric, R.S.3
-
8
-
-
0021021580
-
Coronavirus IBV: Structural characterization of the spike protein
-
Cavanagh, D. Coronavirus IBV: structural characterization of the spike protein. J. Gen. Virol. 64 Pt 12 2577-2583 (1983).
-
(1983)
J. Gen. Virol.
, vol.64
, pp. 2577-2583
-
-
Cavanagh, D.1
-
9
-
-
3042714194
-
Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity
-
Buchholz, U. J. et al. Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity. Proc. Natl Acad. Sci. USA 101, 9804-9809 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 9804-9809
-
-
Buchholz, U.J.1
-
10
-
-
84900416594
-
Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice
-
Coleman, C. M. et al. Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice. Vaccine 32, 3169-3174 (2014).
-
(2014)
Vaccine
, vol.32
, pp. 3169-3174
-
-
Coleman, C.M.1
-
11
-
-
84891885053
-
A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: Implication for developing therapeutics and vaccines
-
Du, L. et al. A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines. PLoS ONE 8, e81587 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Du, L.1
-
12
-
-
84896545485
-
Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines
-
Ma, C. et al. Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: implication for designing novel mucosal MERS vaccines. Vaccine 32, 2100-2108 (2014).
-
(2014)
Vaccine
, vol.32
, pp. 2100-2108
-
-
Ma, C.1
-
13
-
-
84881232247
-
The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies
-
Mou, H. et al. The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies. J. Virol. 87, 9379-9383 (2013).
-
(2013)
J. Virol.
, vol.87
, pp. 9379-9383
-
-
Mou, H.1
-
14
-
-
84901303550
-
A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in middle east respiratory syndrome coronavirus spike protein
-
Du, L. et al. A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in middle east respiratory syndrome coronavirus spike protein. J. Virol. 88, 7045-7053 (2014).
-
(2014)
J. Virol.
, vol.88
, pp. 7045-7053
-
-
Du, L.1
-
15
-
-
84888037046
-
Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody
-
Ohnuma, K. et al. Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody. J. Virol. 87, 13892-13899 (2013).
-
(2013)
J. Virol.
, vol.87
, pp. 13892-13899
-
-
Ohnuma, K.1
-
16
-
-
84904663317
-
Exceptionally potent neutralization of middle East respiratory syndrome coronavirus by human monoclonal antibodies
-
Ying, T. et al. Exceptionally potent neutralization of middle East respiratory syndrome coronavirus by human monoclonal antibodies. J. Virol. 88, 7796-7805 (2014).
-
(2014)
J. Virol.
, vol.88
, pp. 7796-7805
-
-
Ying, T.1
-
17
-
-
84899797757
-
Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein
-
Jiang, L. et al. Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein. Sci. Transl. Med. 6, 234ra259 (2014).
-
(2014)
Sci. Transl. Med.
, vol.6
, pp. 234ra259
-
-
Jiang, L.1
-
18
-
-
84903737162
-
Middle East respiratory syndrome coronavirus quasispecies that include homologues of human isolates revealed through whole-genome analysis and virus cultured from dromedary camels in Saudi Arabia
-
Briese, T. et al. Middle East respiratory syndrome coronavirus quasispecies that include homologues of human isolates revealed through whole-genome analysis and virus cultured from dromedary camels in Saudi Arabia. mBio 5, e01146-14 (2014).
-
(2014)
MBio
, vol.5
, pp. e01146-e01214
-
-
Briese, T.1
-
19
-
-
55749111036
-
A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase i clinical trial
-
Martin, J. E. et al. A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial. Vaccine 26, 6338-6343 (2008).
-
(2008)
Vaccine
, vol.26
, pp. 6338-6343
-
-
Martin, J.E.1
-
20
-
-
1842589262
-
A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice
-
Yang, Z. Y. et al. A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice. Nature 428, 561-564 (2004).
-
(2004)
Nature
, vol.428
, pp. 561-564
-
-
Yang, Z.Y.1
-
21
-
-
0029993858
-
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
-
Naldini, L., Blomer, U., Gage, F. H., Trono, D. & Verma, I. M. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc. Natl Acad. Sci. USA 93, 11382-11388 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 11382-11388
-
-
Naldini, L.1
Blomer, U.2
Gage, F.H.3
Trono, D.4
Verma, I.M.5
-
22
-
-
14144254155
-
Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses
-
Yang, Z. Y. et al. Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses. Proc. Natl Acad. Sci. USA 102, 797-801 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 797-801
-
-
Yang, Z.Y.1
-
23
-
-
0023733838
-
Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells
-
Stevens, T. L. et al. Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature 334, 255-258 (1988).
-
(1988)
Nature
, vol.334
, pp. 255-258
-
-
Stevens, T.L.1
-
24
-
-
0028864849
-
DNA-mediated immunization in mice induces a potent MHC class I-restricted cytotoxic T lymphocyte response to the hepatitis B envelope protein
-
Davis, H. L., Schirmbeck, R., Reimann, J. & Whalen, R. G. DNA-mediated immunization in mice induces a potent MHC class I-restricted cytotoxic T lymphocyte response to the hepatitis B envelope protein. Hum. Gene. Ther. 6, 1447-1456 (1995).
-
(1995)
Hum. Gene. Ther.
, vol.6
, pp. 1447-1456
-
-
Davis, H.L.1
Schirmbeck, R.2
Reimann, J.3
Whalen, R.G.4
-
25
-
-
0033664689
-
DNA vaccination: Antigen presentation and the induction of immunity
-
Shedlock, D. J. & Weiner, D. B. DNA vaccination: antigen presentation and the induction of immunity. J. Leukoc. Biol. 68, 793-806 (2000).
-
(2000)
J. Leukoc. Biol.
, vol.68
, pp. 793-806
-
-
Shedlock, D.J.1
Weiner, D.B.2
-
26
-
-
84878841571
-
Enhancement of Th1 immune responses to recombinant influenza nucleoprotein by Ribi adjuvant
-
Cargnelutti, D. E. et al. Enhancement of Th1 immune responses to recombinant influenza nucleoprotein by Ribi adjuvant. New Microbiol. 36, 145-151 (2013).
-
(2013)
New Microbiol.
, vol.36
, pp. 145-151
-
-
Cargnelutti, D.E.1
-
27
-
-
34648814055
-
Modulation of immune responses in mice to recombinant antigens from PE and PPE families of proteins of Mycobacterium tuberculosis by the Ribi adjuvant
-
Chaitra, M. G., Nayak, R. & Shaila, M. S. Modulation of immune responses in mice to recombinant antigens from PE and PPE families of proteins of Mycobacterium tuberculosis by the Ribi adjuvant. Vaccine 25, 7168-7176 (2007).
-
(2007)
Vaccine
, vol.25
, pp. 7168-7176
-
-
Chaitra, M.G.1
Nayak, R.2
Shaila, M.S.3
-
28
-
-
84881479703
-
Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
-
Lu, G. et al. Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature 500, 227-231 (2013).
-
(2013)
Nature
, vol.500
, pp. 227-231
-
-
Lu, G.1
-
29
-
-
33744910870
-
Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody
-
Prabakaran, P. et al. Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody. J. Biol. Chem. 281, 15829-15836 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15829-15836
-
-
Prabakaran, P.1
-
30
-
-
34547500771
-
Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies
-
Zhu, Z. et al. Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies. Proc. Natl Acad. Sci. USA 104, 12123-12128 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 12123-12128
-
-
Zhu, Z.1
-
31
-
-
84914162074
-
A generic approach to pathological lung segmentation
-
Mansoor, A. et al. A generic approach to pathological lung segmentation. IEEE Trans. Med. Imaging 33, 2293-2310 (2014).
-
(2014)
IEEE Trans. Med. Imaging
, vol.33
, pp. 2293-2310
-
-
Mansoor, A.1
-
32
-
-
84897480727
-
Rapid generation of a mouse model for Middle East respiratory syndrome
-
Zhao, J. et al. Rapid generation of a mouse model for Middle East respiratory syndrome. Proc. Natl Acad. Sci. USA 111, 4970-4975 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 4970-4975
-
-
Zhao, J.1
-
33
-
-
84879760362
-
The Middle East respiratory syndrome coronavirus (MERS-CoV) does not replicate in Syrian hamsters
-
de Wit, E. et al. The Middle East respiratory syndrome coronavirus (MERS-CoV) does not replicate in Syrian hamsters. PLoS ONE 8, e69127 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
De Wit, E.1
-
34
-
-
84900515662
-
Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution
-
Tang, X. C. et al. Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution. Proc. Natl Acad. Sci. USA 111, E2018-E2026 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. E2018-E2026
-
-
Tang, X.C.1
-
35
-
-
0036776650
-
Sustained peptide-specific gamma interferon T-cell response in rhesus macaques immunized with human immunodeficiency virus gag DNA vaccines
-
Caulfield, M. J. et al. Sustained peptide-specific gamma interferon T-cell response in rhesus macaques immunized with human immunodeficiency virus gag DNA vaccines. J. Virol. 76, 10038-10043 (2002).
-
(2002)
J. Virol.
, vol.76
, pp. 10038-10043
-
-
Caulfield, M.J.1
-
36
-
-
27644584129
-
Modulation of the immune response to the severe acute respiratory syndrome spike glycoprotein by gene-based and inactivated virus immunization
-
Kong, W. P. et al. Modulation of the immune response to the severe acute respiratory syndrome spike glycoprotein by gene-based and inactivated virus immunization. J. Virol. 79, 13915-13923 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 13915-13923
-
-
Kong, W.P.1
-
37
-
-
81855182191
-
DNA priming and influenza vaccine immunogenicity: Two phase 1 open label randomised clinical trials
-
Ledgerwood, J. E. et al. DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials. Lancet Infect. Dis. 11, 916-924 (2011).
-
(2011)
Lancet Infect. Dis.
, vol.11
, pp. 916-924
-
-
Ledgerwood, J.E.1
-
38
-
-
84880191764
-
Prime-boost interval matters: A randomized phase 1 study to identify the minimum interval necessary to observe the H5 DNA influenza vaccine priming effect
-
Ledgerwood, J. E. et al. Prime-boost interval matters: a randomized phase 1 study to identify the minimum interval necessary to observe the H5 DNA influenza vaccine priming effect. J. Infect. Dis. 208, 418-422 (2013).
-
(2013)
J. Infect. Dis.
, vol.208
, pp. 418-422
-
-
Ledgerwood, J.E.1
-
39
-
-
84880206390
-
DNA priming prior to inactivated influenza A(H5N1) vaccination expands the antibody epitope repertoire and increases affinity maturation in a boost-interval-dependent manner in adults
-
Khurana, S. et al. DNA priming prior to inactivated influenza A(H5N1) vaccination expands the antibody epitope repertoire and increases affinity maturation in a boost-interval-dependent manner in adults. J. Infect. Dis. 208, 413-417 (2013).
-
(2013)
J. Infect. Dis.
, vol.208
, pp. 413-417
-
-
Khurana, S.1
-
40
-
-
84911383558
-
Effects of human anti-spike protein receptor binding domain antibodies on SARS-coronavirus neutralization escape and fitness
-
Sui, J. et al. Effects of human anti-spike protein receptor binding domain antibodies on SARS-coronavirus neutralization escape and fitness. J. Virol. 88, 13769-13780 (2014).
-
(2014)
J. Virol.
, vol.88
, pp. 13769-13780
-
-
Sui, J.1
-
41
-
-
84887277978
-
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus
-
McLellan, J. S. et al. Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science 342, 592-598 (2013).
-
(2013)
Science
, vol.342
, pp. 592-598
-
-
McLellan, J.S.1
-
42
-
-
84878349946
-
Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody
-
McLellan, J. S. et al. Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science 340, 1113-1117 (2013).
-
(2013)
Science
, vol.340
, pp. 1113-1117
-
-
McLellan, J.S.1
-
43
-
-
21644475386
-
A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates
-
Barouch, D. H. et al. A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates. J. Virol. 79, 8828-8834 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 8828-8834
-
-
Barouch, D.H.1
-
44
-
-
34247201441
-
Phase i clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine
-
Catanzaro, A. T. et al. Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine. Vaccine 25, 4085-4092 (2007).
-
(2007)
Vaccine
, vol.25
, pp. 4085-4092
-
-
Catanzaro, A.T.1
-
45
-
-
33745158157
-
A simple method of estimating fifty per cent endpoints
-
Reed, L. J. & Muench, H. A simple method of estimating fifty per cent endpoints. Am. J. Epidemiol. 27, 493-497 (1938).
-
(1938)
Am. J. Epidemiol.
, vol.27
, pp. 493-497
-
-
Reed, L.J.1
Muench, H.2
-
46
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307-326 (1997).
-
(1997)
Methods Enzymol.
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
47
-
-
34447508216
-
Phaser crystallographic software
-
McCoy, A. J. et al. Phaser crystallographic software. J. Appl. Crystallogr. 40, 658-674 (2007).
-
(2007)
J. Appl. Crystallogr.
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
-
48
-
-
77949535720
-
Features and development of Coot
-
Emsley, P., Lohkamp, B., Scott, W. G. & Cowtan, K. Features and development of Coot. Acta Crystallogr. D Biol. Crystallogr. 66, 486-501 (2010).
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 486-501
-
-
Emsley, P.1
Lohkamp, B.2
Scott, W.G.3
Cowtan, K.4
-
49
-
-
14844321328
-
Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT
-
Blanc, E. et al. Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT. Acta Crystallogr. D Biol. Crystallogr. 60, 2210-2221 (2004).
-
(2004)
Acta Crystallogr. D Biol. Crystallogr.
, vol.60
, pp. 2210-2221
-
-
Blanc, E.1
-
50
-
-
0026468883
-
Three-dimensional structure of an Fv from a human IgM immunoglobulin
-
Fan, Z. C. et al. Three-dimensional structure of an Fv from a human IgM immunoglobulin. J. Mol. Biol. 228, 188-207 (1992).
-
(1992)
J. Mol. Biol.
, vol.228
, pp. 188-207
-
-
Fan, Z.C.1
-
51
-
-
67349103859
-
Structural insights into immune recognition of the severe acute respiratory syndrome coronavirus S protein receptor binding domain
-
Pak, J. E. et al. Structural insights into immune recognition of the severe acute respiratory syndrome coronavirus S protein receptor binding domain. J. Mol. Biol. 388, 815-823 (2009).
-
(2009)
J. Mol. Biol.
, vol.388
, pp. 815-823
-
-
Pak, J.E.1
-
52
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
Adams, P. D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta. Crystallogr. D Biol. Crystallogr. 66, 213-221 (2010).
-
(2010)
Acta. Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
-
53
-
-
74549178560
-
MolProbity: All-atom structure validation for macromolecular crystallography
-
Chen, V. B. et al. MolProbity: all-atom structure validation for macromolecular crystallography. Acta. Crystallogr. D Biol. Crystallogr. 66, 12-21 (2010).
-
(2010)
Acta. Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 12-21
-
-
Chen, V.B.1
-
54
-
-
84885038468
-
Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus
-
Scobey, T. et al. Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus. Proc. Natl Acad. Sci. USA 110, 16157-16162 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 16157-16162
-
-
Scobey, T.1
|