MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

Journal of General Virology

Volumn 94, Issue PART8, 2013, Pages 1749-1760

  de Wilde, Adriaan H ^a   Raj, V Stalin ^b   Oudshoorn, Diede ^a   Bestebroer, Theo M ^b   van Nieuwkoop, Stefan ^b   Limpens, Ronald W A L ^a   Posthuma, Clara C ^a   van der Meer, Yvonne ^a   Bárcena, Montserrat ^a   Haagmans, Bart L ^b   Snijder, Eric J ^a   van den Hoogen, Bernadette G ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CYCLOSPORIN A; VIRUS PROTEIN; VIRUS RNA;

ANIMAL CELL; ARTICLE; CELL CULTURE; CORONAVIRUS; CYTOPATHOLOGY; CYTOTOXICITY; DRUG SCREENING; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; NONHUMAN; PRIORITY JOURNAL; RNA SYNTHESIS; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; CORONAVIRUS; CYCLOSPORINE; CYTOPATHOGENIC EFFECT, VIRAL; DRUG EVALUATION, PRECLINICAL; HUMANS; INTERFERON-ALPHA; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON, TRANSMISSION; VIRUS REPLICATION;

EID: 84880177352     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.052910-0     Document Type: Article

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