Clinical Features and Short-term Outcomes of 144 Patients with SARS in the Greater Toronto Area

JAMA

Volumn 289, Issue 21, 2003, Pages 2801-2809

  Booth, Christopher M ^b   Matukas, Larissa M ^b   Tomlinson, George A ^a,b,f   Rachlis, Anita R ^b,c   Rose, David B ^b,d   Dwosh, Hy A ^b,e   Walmsley, Sharon L ^a,b,f   Mazzulli, Tony ^a,b   Avendano, Monica ^b,g   Derkach, Peter ^b,g   Ephtimios, Issa E ^b,h   Kitai, Ian ^b,i   Mederski, Barbara D ^b,j   Shadowitz, Steven B ^b,c   Gold, Wayne L ^b,f   Hawryluck, Laura A ^a,b,f   Rea, Elizabeth ^b,k   Chenkin, Jordan S ^b   Cescon, David W ^b   Poutanen, Susan M ^a,b   Detsky, Allan S ^a,b,f   more..

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^d SCARBOROUGH HOSPITAL   (Canada)

^e York Central Hospital Richmond Hill   (Canada)

^f UNIVERSITY HEALTH NETWORK   (Canada)

^g West Park Healthcare Centre   (Canada)

^h MARKHAM STOUFFVILLE HOSPITAL   (Canada)

ⁱ Rouge Valley Health System   (Canada)

^j NORTH YORK GENERAL HOSPITAL   (Canada)

^k TORONTO PUBLIC HEALTH   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

LACTATE DEHYDROGENASE; RIBAVIRIN; ANTIINFLAMMATORY AGENT; ANTIVIRUS AGENT; BIOLOGICAL MARKER; HYDROCORTISONE;

ADULT; ARTICLE; ARTIFICIAL VENTILATION; BRADYCARDIA; CANADA; CLINICAL FEATURE; COMORBIDITY; CONFIDENCE INTERVAL; COUGHING; DYSPNEA; FEMALE; FEVER; HEMOLYSIS; HUMAN; HYPOCALCEMIA; INTENSIVE CARE; LYMPHOCYTOPENIA; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; MYALGIA; PRIORITY JOURNAL; RHINORRHEA; SELF REPORT; SEVERE ACUTE RESPIRATORY SYNDROME; SIDE EFFECT; SORE THROAT; VIRUS PNEUMONIA; AGED; BLOOD; COMMUNICABLE DISEASE; DEMOGRAPHY; DISEASE COURSE; EPIDEMIC; HOSPITALIZATION; INFECTION CONTROL; INTENSIVE CARE UNIT; ISOLATION AND PURIFICATION; LUNG; MIDDLE AGED; NONPARAMETRIC TEST; PROPORTIONAL HAZARDS MODEL; RADIOGRAPHY; RETROSPECTIVE STUDY; SARS CORONAVIRUS; SURVIVAL;

ADULT; AGED; ANTI-INFLAMMATORY AGENTS; ANTIVIRAL AGENTS; BIOLOGICAL MARKERS; COMMUNICABLE DISEASES, EMERGING; COMORBIDITY; COUGH; DEMOGRAPHY; DISEASE OUTBREAKS; DISEASE PROGRESSION; DYSPNEA; FEMALE; FEVER; HOSPITALIZATION; HUMANS; HYDROCORTISONE; INFECTION CONTROL; INTENSIVE CARE UNITS; LUNG; MALE; MIDDLE AGED; ONTARIO; PROPORTIONAL HAZARDS MODELS; RESPIRATION, ARTIFICIAL; RETROSPECTIVE STUDIES; RIBAVIRIN; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; STATISTICS, NONPARAMETRIC; SURVIVAL ANALYSIS;

EID: 0037976821     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.289.21.JOC30885     Document Type: Article

References (24)

1. World Health Organization, WHO issues a global alert about cases of atypical pneumonia, Available at; http://www.who.int/csr/sarsarchive/2003_03_12 /en/. Accessed April 29, 2003.
2. World Health Organization, Cumulative number of reported probable cases of severe acute respiratory syndrome (SARS). Available at: http://www.who .int/csr/sarscountry/2003_04_28/en/. Accessed April 29, 2003.
3. World Health Organization. Case definitions for surveillance of severe acute respiratory syndrome (SARS). Available at: http://www.who.int/csr/sars /casedefinition/en. Accessed April 29, 2003.
4. Ksiazek TG, Erdman D, Goldsmith CS, et al. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med. Available at: http://content .nejm.org/cgi/reprint/NEJMoa030781v4.pdf. Accessed May 1, 2003.
5. Drosten C, Gunther S, Preiser W, et al. Identification of a novel virus in patients with severe acute respiratory syndrome. N Engl J Med. Available at: http: //content.nejm.org/cgi/reprint/NEJMoa030747v2 .pdf. Accessed May 1, 2003.
6. British Columbia Genome Sciences Centre. SARS associated coronavirus. Available at: http://www .bcgsc.ca/bioinfo/SARS/. Accessed April 29, 2003.
7. Centers for Disease Control and Prevention. SARS coronavirus sequencing. Available at: http://www .cdc.gov/ncidod/sars/sequence.htm. Accessed April 29, 2003.
8. Poutanen SM, Low DE, Henry B, et al. Identification of severe acute respiratory syndrome in Canada. N Engl J Med. Available at: http://content.nejm.org /cgi/reprint/NEJMoa030634v3.pdf. Accessed May 1, 2003.
9. Tsang KW, Ho PL, Ooi GC, et al. A cluster of cases of severe acute respiratory syndrome in Hong Kong. N Engl J Med. Available at: http://content.nejm.org/cgi /reprint/NEJMoa030666v3.pdf. Accessed May 1, 2003.
10. Lee N, Hui D, Wu A, et al. A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med. Available at: http://content.nejm.org /cgi/reprint/NEJMoa030685v2.pdf. Accessed May 1, 2003.
11. Centers for Disease Control and Prevention. Update: outbreak of severe acute respiratory syndrome-worldwide, 2003. Available at: http://www.cdc.gov /mmwr/preview/mmwrhtml/mm5212a1.htm. Accessed April 29, 2003.
12. Ontario Ministry of Health and Long-term Care. Severe acute respiratory syndrome-update, April 27, 2003. Available at: http://ogov.newswire.ca/ontario /GPOE/2003/04/27/c4792.html?lmatch=〈=_e .html. Accessed April 29, 2003.
13. Ontario Ministry of Health and Long-term Care. Severe acute respiratory syndrome-update, April 19, 2003. Available at: http://ogov.newswire.ca/ontario /GPOE/2003/04/19/c2529.html?lmatch=〈=_e .html. Accessed April 29, 2003.
14. Dwosh HA, Hong HH, Austgarden D, Herman S, Schabas R. Identification and containment of an outbreak of SARS in a community hospital. CMAJ. In press. Available at: http://www.cma.ca/cmaj/early_releases /identification.pdf. Accessed May 1, 2003.
15. Centers for Disease Control and Prevention. Updated interim US case definition of severe acute respiratory syndrome (SARS). Available at: http://www.cdc.gov/ncidod /sars/casedefinition.htm. Accessed April 29, 2003.
16. Cox DR, Oakes D. Analysis of Survival Data. London, England: Chapman & Hall; 1984.
17. Conover WJ. Practical Non-parametric Statistics. 2nd ed. New York, NY: John Wiley & Sons; 1980.
18. Tukey JW. Data-based graphics: visual display in the decades to come. Stat Sci. 1990;5:327-339.
19. Grambsch P, Therneau T. Proportional hazards tests and diagnostics based on weighted residuals. Biometrika. 1994;81:515-526.
20. Harrell FE. Regression Modeling Strategies With Applications to Linear Models, Logistic Regression, and Survival Analysis. New York, NY: Springer-Verlag; 2001.
21. Borio L, Inglesby T, Peters CJ, et al. Hemorrhagic fever viruses as biological weapons: medical and public health management. JAMA. 2002;287:2391-2405.
22. Health Canada. Severe acute respiratory syndrome case definitions. Available at: http://www.hc-sc .gc.ca/pphb-dgspsp/sars-sras/sarscasedef-0317_e .html. Accessed April 29, 2003.
23. Centers for Disease Control and Prevention. Severe acute respiratory syndrome and coronavirus testing-United States, 2003. Available at: http://www .cdc.gov/mmwr/preview/mmwrhtml/mm5214a1 .htm. Accessed April 29, 2003.
24. Mandell LA, Marrie TJ, Grossman RF, et al. Canadian guidelines for the initial management of community-acquired pneumonia. Clin Infect Dis. 2000; 31:383-421.