-
3
-
-
84862765955
-
Managing drug resistance in cancer: lessons from HIV therapy
-
Bock C and Lengauer T. Managing drug resistance in cancer: lessons from HIV therapy. Nature reviews Cancer. 2012; 12:494-501.
-
(2012)
Nature reviews Cancer.
, vol.12
, pp. 494-501
-
-
Bock, C.1
Lengauer, T.2
-
4
-
-
0036279279
-
E2F1 and c-Myc potentiate apoptosis through inhibition of NFkappaB activity that facilitates MnSOD-mediated ROS elimination
-
Tanaka H, Matsumura I, Ezoe S, Satoh Y, Sakamaki T, Albanese C, Machii T, Pestell RG and Kanakura Y. E2F1 and c-Myc potentiate apoptosis through inhibition of NFkappaB activity that facilitates MnSOD-mediated ROS elimination. Molecular cell. 2002; 9:1017-1029.
-
(2002)
Molecular cell.
, vol.9
, pp. 1017-1029
-
-
Tanaka, H.1
Matsumura, I.2
Ezoe, S.3
Satoh, Y.4
Sakamaki, T.5
Albanese, C.6
Machii, T.7
Pestell, R.G.8
Kanakura, Y.9
-
6
-
-
84876931396
-
Beyond oxidative stress: an immunologist's guide to reactive oxygen species
-
Nathan C and Cunningham-Bussel A. Beyond oxidative stress: an immunologist's guide to reactive oxygen species. Nature reviews Immunology. 2013; 13:349-361.
-
(2013)
Nature reviews Immunology.
, vol.13
, pp. 349-361
-
-
Nathan, C.1
Cunningham-Bussel, A.2
-
7
-
-
67650071137
-
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
-
Trachootham D, Alexandre J and Huang P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nature reviews Drug discovery. 2009; 8:579- 591.
-
(2009)
Nature reviews Drug discovery.
, vol.8
, pp. 579-591
-
-
Trachootham, D.1
Alexandre, J.2
Huang, P.3
-
8
-
-
84878711134
-
Role of glutathione in cancer progression and chemoresistance
-
Traverso N, Ricciarelli R, Nitti M, Marengo B, Furfaro AL, Pronzato MA, Marinari UM and Domenicotti C. Role of glutathione in cancer progression and chemoresistance. Oxidative medicine and cellular longevity. 2013; 2013:972913.
-
(2013)
Oxidative medicine and cellular longevity.
, vol.2013
, pp. 972913
-
-
Traverso, N.1
Ricciarelli, R.2
Nitti, M.3
Marengo, B.4
Furfaro, A.L.5
Pronzato, M.A.6
Marinari, U.M.7
Domenicotti, C.8
-
9
-
-
0032562527
-
Coordinate changes in expression of protective genes in drug-resistant cells
-
Tew KD, O'Brien M, Laing NM and Shen H. Coordinate changes in expression of protective genes in drug-resistant cells. Chemico-biological interactions. 1998; 111-112:199- 211.
-
(1998)
Chemico-biological interactions.
, vol.111-112
, pp. 199- 211
-
-
Tew, K.D.1
O'Brien, M.2
Laing, N.M.3
Shen, H.4
-
10
-
-
0036364467
-
Multidrug resistance in cancer: role of ATP-dependent transporters
-
Gottesman MM, Fojo T and Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nature reviews Cancer. 2002; 2:48-58.
-
(2002)
Nature reviews Cancer.
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
12
-
-
2342453921
-
Death receptors in chemotherapy and cancer
-
Debatin KM and Krammer PH. Death receptors in chemotherapy and cancer. Oncogene. 2004; 23:2950-2966.
-
(2004)
Oncogene.
, vol.23
, pp. 2950-2966
-
-
Debatin, K.M.1
Krammer, P.H.2
-
13
-
-
9244224723
-
Intrinsic tumour suppression
-
Lowe SW, Cepero E and Evan G. Intrinsic tumour suppression. Nature. 2004; 432:307-315.
-
(2004)
Nature.
, vol.432
, pp. 307-315
-
-
Lowe, S.W.1
Cepero, E.2
Evan, G.3
-
14
-
-
84890859575
-
Towards understanding promiscuity in multidrug efflux pumps
-
Wong K, Ma J, Rothnie A, Biggin PC and Kerr ID. Towards understanding promiscuity in multidrug efflux pumps. Trends in biochemical sciences. 2014; 39:8-16.
-
(2014)
Trends in biochemical sciences.
, vol.39
, pp. 8-16
-
-
Wong, K.1
Ma, J.2
Rothnie, A.3
Biggin, P.C.4
Kerr, I.D.5
-
15
-
-
0022534951
-
A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria
-
Higgins CF, Hiles ID, Salmond GP, Gill DR, Downie JA, Evans IJ, Holland IB, Gray L, Buckel SD, Bell AW, Hermodsend MA. A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria. Nature. 1986; 323:448-450.
-
(1986)
Nature.
, vol.323
, pp. 448-450
-
-
Higgins, C.F.1
Hiles, I.D.2
Salmond, G.P.3
Gill, D.R.4
Downie, J.A.5
Evans, I.J.6
Holland, I.B.7
Gray, L.8
Buckel, S.D.9
Bell, A.W.10
Hermodsend, M.A.11
-
16
-
-
34147214716
-
Multiple molecular mechanisms for multidrug resistance transporters
-
Higgins CF. Multiple molecular mechanisms for multidrug resistance transporters. Nature. 2007; 446:749-757.
-
(2007)
Nature.
, vol.446
, pp. 749-757
-
-
Higgins, C.F.1
-
18
-
-
0029121417
-
Covalent modification of human P-glycoprotein mutants containing a single cysteine in either nucleotide-binding fold abolishes drug-stimulated ATPase activity
-
Loo TW and Clarke DM. Covalent modification of human P-glycoprotein mutants containing a single cysteine in either nucleotide-binding fold abolishes drug-stimulated ATPase activity. The Journal of biological chemistry. 1995; 270:22957-22961.
-
(1995)
The Journal of biological chemistry.
, vol.270
, pp. 22957-22961
-
-
Loo, T.W.1
Clarke, D.M.2
-
19
-
-
84867883248
-
Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans
-
Jin MS, Oldham ML, Zhang Q and Chen J. Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans. Nature. 2012; 490:566-569.
-
(2012)
Nature.
, vol.490
, pp. 566-569
-
-
Jin, M.S.1
Oldham, M.L.2
Zhang, Q.3
Chen, J.4
-
20
-
-
84888581611
-
Targeting multidrug resistance protein 1 (MRP1, ABCC1): past, present, and future
-
Cole SP. Targeting multidrug resistance protein 1 (MRP1, ABCC1): past, present, and future. Annual review of pharmacology and toxicology. 2014; 54:95-117.
-
(2014)
Annual review of pharmacology and toxicology.
, vol.54
, pp. 95-117
-
-
Cole, S.P.1
-
21
-
-
33750046916
-
The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function
-
Chen Q, Yang Y, Li L and Zhang JT. The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function. The Journal of biological chemistry. 2006; 281:31152-31163.
-
(2006)
The Journal of biological chemistry.
, vol.281
, pp. 31152-31163
-
-
Chen, Q.1
Yang, Y.2
Li, L.3
Zhang, J.T.4
-
22
-
-
0037882044
-
Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1)
-
Leslie EM, Letourneau IJ, Deeley RG and Cole SP. Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1). Biochemistry. 2003; 42:5214-5224.
-
(2003)
Biochemistry.
, vol.42
, pp. 5214-5224
-
-
Leslie, E.M.1
Letourneau, I.J.2
Deeley, R.G.3
Cole, S.P.4
-
23
-
-
0037113970
-
Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein
-
Yang Y, Chen Q and Zhang JT. Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein The Journal of biological chemistry. 2002; 277:44268- 44277.
-
(2002)
The Journal of biological chemistry.
, vol.277
, pp. 44268-44277
-
-
Yang, Y.1
Chen, Q.2
Zhang, J.T.3
-
24
-
-
34247851070
-
Regulation of function by dimerization through the amino-terminal membrane-spanning domain of human ABCC1/MRP1
-
Yang Y, Liu Y, Dong Z, Xu J, Peng H, Liu Z and Zhang JT. Regulation of function by dimerization through the amino-terminal membrane-spanning domain of human ABCC1/MRP1. The Journal of biological chemistry. 2007; 282:8821-8830.
-
(2007)
The Journal of biological chemistry.
, vol.282
, pp. 8821-8830
-
-
Yang, Y.1
Liu, Y.2
Dong, Z.3
Xu, J.4
Peng, H.5
Liu, Z.6
Zhang, J.T.7
-
25
-
-
84863010960
-
Human ABCC1 interacts and colocalizes with ATP synthase alpha, revealed by interactive proteomics analysis
-
Yang Y, Li Z, Mo W, Ambadipudi R, Arnold RJ, Hrncirova P, Novotny MV, Georges E and Zhang JT. Human ABCC1 interacts and colocalizes with ATP synthase alpha, revealed by interactive proteomics analysis. Journal of proteome research. 2012; 11:1364-1372.
-
(2012)
Journal of proteome research.
, vol.11
, pp. 1364-1372
-
-
Yang, Y.1
Li, Z.2
Mo, W.3
Ambadipudi, R.4
Arnold, R.J.5
Hrncirova, P.6
Novotny, M.V.7
Georges, E.8
Zhang, J.T.9
-
26
-
-
80255129401
-
Genetic determinants of oxidative stressmediated sensitization of drug-resistant cancer cells
-
Maiti AK. Genetic determinants of oxidative stressmediated sensitization of drug-resistant cancer cells. International journal of cancer. 2012; 130:1-9.
-
(2012)
International journal of cancer.
, vol.130
, pp. 1-9
-
-
Maiti, A.K.1
-
27
-
-
33846304267
-
MRP1/GS-X pump ATPase expression: is this the explanation for the cytoprotection of the heart against oxidative stress-induced redox imbalance in comparison to skeletal muscle cells?
-
Krause MS, Oliveira LP, Jr., Silveira EM, Vianna DR, Rossato JS, Almeida BS, Rodrigues MF, Fernandes AJ, Costa JA, Curi R and de Bittencourt PI, Jr. MRP1/GS-X pump ATPase expression: is this the explanation for the cytoprotection of the heart against oxidative stress-induced redox imbalance in comparison to skeletal muscle cells? Cell biochemistry and function. 2007; 25:23-32.
-
(2007)
Cell biochemistry and function.
, vol.25
, pp. 23-32
-
-
Krause, M.S.1
Oliveira, L.P.2
Silveira, E.M.3
Vianna, D.R.4
Rossato, J.S.5
Almeida, B.S.6
Rodrigues, M.F.7
Fernandes, A.J.8
Costa, J.A.9
Curi, R.10
de Bittencourt, P.I.11
-
29
-
-
33746679778
-
Human ABC transporter ABCG2 in xenobiotic protection and redox biology
-
Wakabayashi K, Tamura A, Saito H, Onishi Y and Ishikawa T. Human ABC transporter ABCG2 in xenobiotic protection and redox biology. Drug metabolism reviews. 2006; 38:371-391.
-
(2006)
Drug metabolism reviews.
, vol.38
, pp. 371-391
-
-
Wakabayashi, K.1
Tamura, A.2
Saito, H.3
Onishi, Y.4
Ishikawa, T.5
-
30
-
-
0042068263
-
A functional study on polymorphism of the ATP-binding cassette transporter ABCG2: critical role of arginine-482 in methotrexate transport
-
Mitomo H, Kato R, Ito A, Kasamatsu S, Ikegami Y, Kii I, Kudo A, Kobatake E, Sumino Y and Ishikawa T. A functional study on polymorphism of the ATP-binding cassette transporter ABCG2: critical role of arginine-482 in methotrexate transport. The Biochemical journal. 2003; 373:767-774.
-
(2003)
The Biochemical journal.
, vol.373
, pp. 767-774
-
-
Mitomo, H.1
Kato, R.2
Ito, A.3
Kasamatsu, S.4
Ikegami, Y.5
Kii, I.6
Kudo, A.7
Kobatake, E.8
Sumino, Y.9
Ishikawa, T.10
-
31
-
-
27744459366
-
Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2
-
Henriksen U, Fog JU, Litman T and Gether U. Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2. The Journal of biological chemistry. 2005; 280:36926-36934.
-
(2005)
The Journal of biological chemistry.
, vol.280
, pp. 36926-36934
-
-
Henriksen, U.1
Fog, J.U.2
Litman, T.3
Gether, U.4
-
32
-
-
30344485123
-
Role of Cys-603 in dimer/oligomer formation of the breast cancer resistance protein BCRP/ABCG2
-
Kage K, Fujita T and Sugimoto Y. Role of Cys-603 in dimer/oligomer formation of the breast cancer resistance protein BCRP/ABCG2. Cancer science. 2005; 96:866-872.
-
(2005)
Cancer science.
, vol.96
, pp. 866-872
-
-
Kage, K.1
Fujita, T.2
Sugimoto, Y.3
-
33
-
-
33646703561
-
Identification of cysteine residues critically involved in homodimer formation and protein expression of human ATP-binding cassette transporter ABCG2: a new approach using the flp recombinase system
-
Wakabayashi K, Nakagawa H, Adachi T, Kii I, Kobatake E, Kudo A and Ishikawa T. Identification of cysteine residues critically involved in homodimer formation and protein expression of human ATP-binding cassette transporter ABCG2: a new approach using the flp recombinase system. Journal of experimental therapeutics & oncology. 2006; 5:205-222.
-
(2006)
Journal of experimental therapeutics & oncology.
, vol.5
, pp. 205-222
-
-
Wakabayashi, K.1
Nakagawa, H.2
Adachi, T.3
Kii, I.4
Kobatake, E.5
Kudo, A.6
Ishikawa, T.7
-
34
-
-
45749107106
-
Effect of cysteine mutagenesis on the function and disulfide bond formation of human ABCG2
-
Liu Y, Yang Y, Qi J, Peng H and Zhang JT. Effect of cysteine mutagenesis on the function and disulfide bond formation of human ABCG2. The Journal of pharmacology and experimental therapeutics. 2008; 326:33-40.
-
(2008)
The Journal of pharmacology and experimental therapeutics.
, vol.326
, pp. 33-40
-
-
Liu, Y.1
Yang, Y.2
Qi, J.3
Peng, H.4
Zhang, J.T.5
-
35
-
-
0037358040
-
Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting p-glycoprotein
-
Thomas H and Coley HM. Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting p-glycoprotein. Cancer control. 2003; 10:159-165.
-
(2003)
Cancer control.
, vol.10
, pp. 159-165
-
-
Thomas, H.1
Coley, H.M.2
-
36
-
-
77955488723
-
Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype
-
Singh A, Wu H, Zhang P, Happel C, Ma J and Biswal S. Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype. Molecular cancer therapeutics. 2010; 9:2365-2376.
-
(2010)
Molecular cancer therapeutics.
, vol.9
, pp. 2365-2376
-
-
Singh, A.1
Wu, H.2
Zhang, P.3
Happel, C.4
Ma, J.5
Biswal, S.6
-
37
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M and Talalay P. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proceedings of the National Academy of Sciences of the United States of America. 2002; 99:11908-11913.
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America.
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
Yamamoto, M.7
Talalay, P.8
-
38
-
-
33644856080
-
The double-edged sword of Nrf2: subversion of redox homeostasis during the evolution of cancer
-
Hayes JD and McMahon M. The double-edged sword of Nrf2: subversion of redox homeostasis during the evolution of cancer. Molecular cell. 2006; 21:732-734.
-
(2006)
Molecular cell.
, vol.21
, pp. 732-734
-
-
Hayes, J.D.1
McMahon, M.2
-
39
-
-
56649083534
-
Dual roles of Nrf2 in cancer
-
Lau A, Villeneuve NF, Sun Z, Wong PK and Zhang DD. Dual roles of Nrf2 in cancer. Pharmacological research. 2008; 58:262-270.
-
(2008)
Pharmacological research.
, vol.58
, pp. 262-270
-
-
Lau, A.1
Villeneuve, N.F.2
Sun, Z.3
Wong, P.K.4
Zhang, D.D.5
-
40
-
-
46949099638
-
Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2
-
Wang XJ, Sun Z, Villeneuve NF, Zhang S, Zhao F, Li Y, Chen W, Yi X, Zheng W, Wondrak GT, Wong PK and Zhang DD. Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2. Carcinogenesis. 2008; 29:1235-1243.
-
(2008)
Carcinogenesis.
, vol.29
, pp. 1235-1243
-
-
Wang, X.J.1
Sun, Z.2
Villeneuve, N.F.3
Zhang, S.4
Zhao, F.5
Li, Y.6
Chen, W.7
Yi, X.8
Zheng, W.9
Wondrak, G.T.10
Wong, P.K.11
Zhang, D.D.12
-
41
-
-
74049120454
-
Nrf2: friend or foe for chemoprevention?
-
Kensler TW and Wakabayashi N. Nrf2: friend or foe for chemoprevention? Carcinogenesis. 2010; 31:90-99.
-
(2010)
Carcinogenesis.
, vol.31
, pp. 90-99
-
-
Kensler, T.W.1
Wakabayashi, N.2
-
42
-
-
84883736109
-
Oncogenic functions of the transcription factor Nrf2
-
Ganan-Gomez I, Wei Y, Yang H, Boyano-Adanez MC and Garcia-Manero G. Oncogenic functions of the transcription factor Nrf2. Free radical biology & medicine. 2013; 65:750- 764.
-
(2013)
Free radical biology & medicine.
, vol.65
, pp. 750-764
-
-
Ganan-Gomez, I.1
Wei, Y.2
Yang, H.3
Boyano-Adanez, M.C.4
Garcia-Manero, G.5
-
43
-
-
84864348569
-
NRF2 and cancer: the good, the bad and the importance of context
-
Sporn MB and Liby KT. NRF2 and cancer: the good, the bad and the importance of context. Nature reviews Cancer. 2012; 12:564-571.
-
(2012)
Nature reviews Cancer.
, vol.12
, pp. 564-571
-
-
Sporn, M.B.1
Liby, K.T.2
-
44
-
-
46649112474
-
Increased expression of Nrf2/ ARE-dependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells
-
Kim SK, Yang JW, Kim MR, Roh SH, Kim HG, Lee KY, Jeong HG and Kang KW. Increased expression of Nrf2/ ARE-dependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells. Free radical biology & medicine. 2008; 45:537-546.
-
(2008)
Free radical biology & medicine.
, vol.45
, pp. 537-546
-
-
Kim, S.K.1
Yang, J.W.2
Kim, M.R.3
Roh, S.H.4
Kim, H.G.5
Lee, K.Y.6
Jeong, H.G.7
Kang, K.W.8
-
46
-
-
50849127129
-
Combined action and regulation of phase II enzymes and multidrug resistance proteins in multidrug resistance in cancer
-
Meijerman I, Beijnen JH and Schellens JH. Combined action and regulation of phase II enzymes and multidrug resistance proteins in multidrug resistance in cancer. Cancer treatment reviews. 2008; 34:505-520.
-
(2008)
Cancer treatment reviews.
, vol.34
, pp. 505-520
-
-
Meijerman, I.1
Beijnen, J.H.2
Schellens, J.H.3
-
47
-
-
85027913464
-
Oxidative stress, mammospheres and Nrf2-new implication for breast cancer therapy?
-
Wu T, Harder BG, Wong PK, Lang JE and Zhang DD. Oxidative stress, mammospheres and Nrf2-new implication for breast cancer therapy? Molecular carcinogenesis. 2014.
-
(2014)
Molecular carcinogenesis
-
-
Wu, T.1
Harder, B.G.2
Wong, P.K.3
Lang, J.E.4
Zhang, D.D.5
-
49
-
-
35548930209
-
The emerging roles of forkhead box (Fox) proteins in cancer
-
Myatt SS and Lam EW. The emerging roles of forkhead box (Fox) proteins in cancer. Nature reviews Cancer. 2007; 7:847-859.
-
(2007)
Nature reviews Cancer.
, vol.7
, pp. 847-859
-
-
Myatt, S.S.1
Lam, E.W.2
-
50
-
-
61349137083
-
A new fork for clinical application: targeting forkhead transcription factors in cancer
-
Yang JY and Hung MC. A new fork for clinical application: targeting forkhead transcription factors in cancer. Clinical cancer research. 2009; 15:752-757.
-
(2009)
Clinical cancer research.
, vol.15
, pp. 752-757
-
-
Yang, J.Y.1
Hung, M.C.2
-
52
-
-
84879810916
-
Role and regulation of the forkhead transcription factors FOXO3a and FOXM1 in carcinogenesis and drug resistance
-
Gomes AR, Zhao F and Lam EW. Role and regulation of the forkhead transcription factors FOXO3a and FOXM1 in carcinogenesis and drug resistance. Chinese journal of cancer. 2013; 32:365-370.
-
(2013)
Chinese journal of cancer.
, vol.32
, pp. 365-370
-
-
Gomes, A.R.1
Zhao, F.2
Lam, E.W.3
-
53
-
-
84879701384
-
SIRT1-mediated FoxO1 deacetylation is essential for multidrug resistance-associated protein 2 expression in tamoxifen-resistant breast cancer cells
-
Choi HK, Cho KB, Phuong NT, Han CY, Han HK, Hien TT, Choi HS and Kang KW. SIRT1-mediated FoxO1 deacetylation is essential for multidrug resistance-associated protein 2 expression in tamoxifen-resistant breast cancer cells. Molecular pharmaceutics. 2013; 10:2517-2527.
-
(2013)
Molecular pharmaceutics.
, vol.10
, pp. 2517-2527
-
-
Choi, H.K.1
Cho, K.B.2
Phuong, N.T.3
Han, C.Y.4
Han, H.K.5
Hien, T.T.6
Choi, H.S.7
Kang, K.W.8
-
54
-
-
51849147067
-
Role of FoxO1 activation in MDR1 expression in adriamycinresistant breast cancer cells
-
Han CY, Cho KB, Choi HS, Han HK and Kang KW. Role of FoxO1 activation in MDR1 expression in adriamycinresistant breast cancer cells. Carcinogenesis. 2008; 29:1837- 1844.
-
(2008)
Carcinogenesis.
, vol.29
, pp. 1837- 1844
-
-
Han, C.Y.1
Cho, K.B.2
Choi, H.S.3
Han, H.K.4
Kang, K.W.5
-
55
-
-
84874253916
-
Redoxdependent control of FOXO/DAF-16 by transportin-1
-
Putker M, Madl T, Vos HR, de Ruiter H, Visscher M, van den Berg MC, Kaplan M, Korswagen HC, Boelens R, Vermeulen M, Burgering BM and Dansen TB. Redoxdependent control of FOXO/DAF-16 by transportin-1. Molecular cell. 2013; 49:730-742.
-
(2013)
Molecular cell.
, vol.49
, pp. 730-742
-
-
Putker, M.1
Madl, T.2
Vos, H.R.3
de Ruiter, H.4
Visscher, M.5
van den Berg, M.C.6
Kaplan, M.7
Korswagen, H.C.8
Boelens, R.9
Vermeulen, M.10
Burgering, B.M.11
Dansen, T.B.12
-
56
-
-
84929959648
-
Thioredoxin 1 upregulates FOXO1 transcriptional activity in drug resistance in ovarian cancer cells
-
Wang J, Yang H, Li W, Xu H, Yang X and Gan L. Thioredoxin 1 upregulates FOXO1 transcriptional activity in drug resistance in ovarian cancer cells. Biochimica et biophysica acta. 2015; 1852:395-405.
-
(2015)
Biochimica et biophysica acta.
, vol.1852
, pp. 395-405
-
-
Wang, J.1
Yang, H.2
Li, W.3
Xu, H.4
Yang, X.5
Gan, L.6
-
57
-
-
77952476474
-
Transcriptional role of FOXO1 in drug resistance through antioxidant defense systems
-
Goto T and Takano M. Transcriptional role of FOXO1 in drug resistance through antioxidant defense systems. Advances in experimental medicine and biology. 2009; 665:171-179.
-
(2009)
Advances in experimental medicine and biology.
, vol.665
, pp. 171-179
-
-
Goto, T.1
Takano, M.2
-
58
-
-
84859104051
-
IKK-beta mediates chemoresistance by sequestering FOXO3; a critical factor for cell survival and death
-
Tezil T, Bodur C, Kutuk O and Basaga H. IKK-beta mediates chemoresistance by sequestering FOXO3; a critical factor for cell survival and death. Cellular signalling. 2012; 24:1361-1368.
-
(2012)
Cellular signalling.
, vol.24
, pp. 1361-1368
-
-
Tezil, T.1
Bodur, C.2
Kutuk, O.3
Basaga, H.4
-
59
-
-
77953208940
-
Foxo3a expression and acetylation regulate cancer cell growth and sensitivity to cisplatin
-
Shiota M, Yokomizo A, Kashiwagi E, Tada Y, Inokuchi J, Tatsugami K, Kuroiwa K, Uchiumi T, Seki N and Naito S. Foxo3a expression and acetylation regulate cancer cell growth and sensitivity to cisplatin. Cancer science. 2010; 101:1177-1185.
-
(2010)
Cancer science.
, vol.101
, pp. 1177-1185
-
-
Shiota, M.1
Yokomizo, A.2
Kashiwagi, E.3
Tada, Y.4
Inokuchi, J.5
Tatsugami, K.6
Kuroiwa, K.7
Uchiumi, T.8
Seki, N.9
Naito, S.10
-
60
-
-
84875423827
-
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
-
Shiloh Y and Ziv Y. The ATM protein kinase: regulating the cellular response to genotoxic stress, and more. Nature reviews Molecular cell biology. 2013; 14:197-210.
-
(2013)
Nature reviews Molecular cell biology.
, vol.14
, pp. 197-210
-
-
Shiloh, Y.1
Ziv, Y.2
-
61
-
-
77958191599
-
ATM activation by oxidative stress
-
Guo Z, Kozlov S, Lavin MF, Person MD and Paull TT. ATM activation by oxidative stress. Science. 2010; 330:517-521.
-
(2010)
Science.
, vol.330
, pp. 517-521
-
-
Guo, Z.1
Kozlov, S.2
Lavin, M.F.3
Person, M.D.4
Paull, T.T.5
-
62
-
-
78650378982
-
ATM activation in the presence of oxidative stress
-
Guo Z, Deshpande R and Paull TT. ATM activation in the presence of oxidative stress. Cell cycle. 2010; 9:4805-4811.
-
(2010)
Cell cycle.
, vol.9
, pp. 4805-4811
-
-
Guo, Z.1
Deshpande, R.2
Paull, T.T.3
-
63
-
-
84874588590
-
Camptothecin and cisplatin upregulate ABCG2 and MRP2 expression by activating the ATM/NF-kappaB pathway in lung cancer cells
-
Ke SZ, Ni XY, Zhang YH, Wang YN, Wu B and Gao FG. Camptothecin and cisplatin upregulate ABCG2 and MRP2 expression by activating the ATM/NF-kappaB pathway in lung cancer cells. International journal of oncology. 2013; 42:1289-1296.
-
(2013)
International journal of oncology.
, vol.42
, pp. 1289-1296
-
-
Ke, S.Z.1
Ni, X.Y.2
Zhang, Y.H.3
Wang, Y.N.4
Wu, B.5
Gao, F.G.6
-
64
-
-
0023508529
-
Phosphorylation of the multidrug resistance associated glycoprotein
-
Mellado W and Horwitz SB. Phosphorylation of the multidrug resistance associated glycoprotein. Biochemistry. 1987; 26:6900-6904.
-
(1987)
Biochemistry.
, vol.26
, pp. 6900-6904
-
-
Mellado, W.1
Horwitz, S.B.2
-
65
-
-
33746922414
-
Oxidant-induced activation of type I protein kinase A is mediated by RI subunit interprotein disulfide bond formation
-
Brennan JP, Bardswell SC, Burgoyne JR, Fuller W, Schroder E, Wait R, Begum S, Kentish JC and Eaton P. Oxidant-induced activation of type I protein kinase A is mediated by RI subunit interprotein disulfide bond formation. The Journal of biological chemistry. 2006; 281:21827-21836.
-
(2006)
The Journal of biological chemistry.
, vol.281
, pp. 21827-21836
-
-
Brennan, J.P.1
Bardswell, S.C.2
Burgoyne, J.R.3
Fuller, W.4
Schroder, E.5
Wait, R.6
Begum, S.7
Kentish, J.C.8
Eaton, P.9
-
66
-
-
77955916237
-
Redox control of protein kinase C: cell- and disease-specific aspects
-
Giorgi C, Agnoletto C, Baldini C, Bononi A, Bonora M, Marchi S, Missiroli S, Patergnani S, Poletti F, Rimessi A, Zavan B and Pinton P. Redox control of protein kinase C: cell- and disease-specific aspects. Antioxidants & redox signaling. 2010; 13:1051-1085.
-
(2010)
Antioxidants & redox signaling.
, vol.13
, pp. 1051-1085
-
-
Giorgi, C.1
Agnoletto, C.2
Baldini, C.3
Bononi, A.4
Bonora, M.5
Marchi, S.6
Missiroli, S.7
Patergnani, S.8
Poletti, F.9
Rimessi, A.10
Zavan, B.11
Pinton, P.12
-
67
-
-
0027439693
-
Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells
-
Blobe GC, Sachs CW, Khan WA, Fabbro D, Stabel S, Wetsel WC, Obeid LM, Fine RL and Hannun YA. Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha. The Journal of biological chemistry. 1993; 268:658-664.
-
(1993)
Functional significance of enhanced expression of PKC alpha. The Journal of biological chemistry.
, vol.268
, pp. 658-664
-
-
Blobe, G.C.1
Sachs, C.W.2
Khan, W.A.3
Fabbro, D.4
Stabel, S.5
Wetsel, W.C.6
Obeid, L.M.7
Fine, R.L.8
Hannun, Y.A.9
-
68
-
-
0027853682
-
Differential modulation of P-glycoprotein transport by protein kinase inhibition
-
Bates SE, Lee JS, Dickstein B, Spolyar M and Fojo AT. Differential modulation of P-glycoprotein transport by protein kinase inhibition. Biochemistry. 1993; 32:9156- 9164.
-
(1993)
Biochemistry.
, vol.32
, pp. 9156- 9164
-
-
Bates, S.E.1
Lee, J.S.2
Dickstein, B.3
Spolyar, M.4
Fojo, A.T.5
-
69
-
-
0033036722
-
Phosphorylation of P-glycoprotein by PKA and PKC modulates swelling-activated Cl- currents
-
Vanoye CG, Castro AF, Pourcher T, Reuss L and Altenberg GA. Phosphorylation of P-glycoprotein by PKA and PKC modulates swelling-activated Cl- currents. The American journal of physiology. 1999; 276:C370-378.
-
(1999)
The American journal of physiology.
, vol.276
, pp. C370-378
-
-
Vanoye, C.G.1
Castro, A.F.2
Pourcher, T.3
Reuss, L.4
Altenberg, G.A.5
-
70
-
-
84855270724
-
Expression and promoter methylation analysis of ATP-binding cassette genes in pancreatic cancer
-
Chen M, Xue X, Wang F, An Y, Tang D, Xu Y, Wang H, Yuan Z, Gao W, Wei J, Zhang J and Miao Y. Expression and promoter methylation analysis of ATP-binding cassette genes in pancreatic cancer. Oncology reports. 2012; 27:265- 269.
-
(2012)
Oncology reports.
, vol.27
, pp. 265- 269
-
-
Chen, M.1
Xue, X.2
Wang, F.3
An, Y.4
Tang, D.5
Xu, Y.6
Wang, H.7
Yuan, Z.8
Gao, W.9
Wei, J.10
Zhang, J.11
Miao, Y.12
-
71
-
-
18744411280
-
MDR1, chemotherapy and chromatin remodeling
-
Baker EK and El-Osta A. MDR1, chemotherapy and chromatin remodeling. Cancer biology & therapy. 2004; 3:819-824.
-
(2004)
Cancer biology & therapy.
, vol.3
, pp. 819-824
-
-
Baker, E.K.1
El-Osta, A.2
-
72
-
-
28544432478
-
Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs
-
Baker EK, Johnstone RW, Zalcberg JR and El-Osta A. Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs. Oncogene. 2005; 24:8061-8075.
-
(2005)
Oncogene.
, vol.24
, pp. 8061-8075
-
-
Baker, E.K.1
Johnstone, R.W.2
Zalcberg, J.R.3
El-Osta, A.4
-
73
-
-
84870175096
-
Inhibition of hepatic methionine adenosyltransferase by peroxides contaminating parenteral nutrition leads to a lower level of glutathione in newborn Guinea pigs
-
Elremaly W, Rouleau T and Lavoie JC. Inhibition of hepatic methionine adenosyltransferase by peroxides contaminating parenteral nutrition leads to a lower level of glutathione in newborn Guinea pigs. Free radical biology & medicine. 2012; 53:2250-2255.
-
(2012)
Free radical biology & medicine.
, vol.53
, pp. 2250-2255
-
-
Elremaly, W.1
Rouleau, T.2
Lavoie, J.C.3
-
75
-
-
33646517942
-
Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo
-
Alexandre J, Batteux F, Nicco C, Chereau C, Laurent A, Guillevin L, Weill B and Goldwasser F. Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo. International journal of cancer. 2006; 119:41-48.
-
(2006)
International journal of cancer.
, vol.119
, pp. 41-48
-
-
Alexandre, J.1
Batteux, F.2
Nicco, C.3
Chereau, C.4
Laurent, A.5
Guillevin, L.6
Weill, B.7
Goldwasser, F.8
-
76
-
-
37849018320
-
Antioxidants block proteasome inhibitor function in endometrial carcinoma cells
-
Llobet D, Eritja N, Encinas M, Sorolla A, Yeramian A, Schoenenberger JA, Llombart-Cussac A, Marti RM, Matias-Guiu X and Dolcet X. Antioxidants block proteasome inhibitor function in endometrial carcinoma cells. Anti-cancer drugs. 2008; 19:115-124.
-
(2008)
Anti-cancer drugs.
, vol.19
, pp. 115-124
-
-
Llobet, D.1
Eritja, N.2
Encinas, M.3
Sorolla, A.4
Yeramian, A.5
Schoenenberger, J.A.6
Llombart-Cussac, A.7
Marti, R.M.8
Matias-Guiu, X.9
Dolcet, X.10
-
77
-
-
24944500925
-
Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients
-
Bairati I, Meyer F, Gelinas M, Fortin A, Nabid A, Brochet F, Mercier JP, Tetu B, Harel F, Abdous B, Vigneault E, Vass S, Del Vecchio P and Roy J. Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients. Journal of clinical oncology. 2005; 23:5805-5813.
-
(2005)
Journal of clinical oncology.
, vol.23
, pp. 5805-5813
-
-
Bairati, I.1
Meyer, F.2
Gelinas, M.3
Fortin, A.4
Nabid, A.5
Brochet, F.6
Mercier, J.P.7
Tetu, B.8
Harel, F.9
Abdous, B.10
Vigneault, E.11
Vass, S.12
Del Vecchio, P.13
Roy, J.14
-
78
-
-
0027053057
-
Relationship of cellular glutathione to the cytotoxicity and resistance of seven platinum compounds
-
Meijer C, Mulder NH, Timmer-Bosscha H, Sluiter WJ, Meersma GJ and de Vries EG. Relationship of cellular glutathione to the cytotoxicity and resistance of seven platinum compounds. Cancer research. 1992; 52:6885- 6889.
-
(1992)
Cancer research.
, vol.52
, pp. 6885- 6889
-
-
Meijer, C.1
Mulder, N.H.2
Timmer-Bosscha, H.3
Sluiter, W.J.4
Meersma, G.J.5
de Vries, E.G.6
-
79
-
-
0022214278
-
Role of uridine phosphorylase in the anabolism of 5-fluorouracil
-
Schwartz PM, Moir RD, Hyde CM, Turek PJ and Handschumacher RE. Role of uridine phosphorylase in the anabolism of 5-fluorouracil. Biochemical pharmacology. 1985; 34:3585-3589.
-
(1985)
Biochemical pharmacology.
, vol.34
, pp. 3585-3589
-
-
Schwartz, P.M.1
Moir, R.D.2
Hyde, C.M.3
Turek, P.J.4
Handschumacher, R.E.5
-
80
-
-
0020563004
-
Elucidation of pathways of 5-fluorouracil metabolism in xenografts of human colorectal adenocarcinoma
-
Houghton JA and Houghton PJ. Elucidation of pathways of 5-fluorouracil metabolism in xenografts of human colorectal adenocarcinoma. European journal of cancer & clinical oncology. 1983; 19:807-815.
-
(1983)
European journal of cancer & clinical oncology.
, vol.19
, pp. 807-815
-
-
Houghton, J.A.1
Houghton, P.J.2
-
81
-
-
0036057596
-
Clinical studies of three oral prodrugs of 5-fluorouracil (capecitabine, UFT, S-1): a review
-
Malet-Martino M and Martino R. Clinical studies of three oral prodrugs of 5-fluorouracil (capecitabine, UFT, S-1): a review. The oncologist. 2002; 7:288-323.
-
(2002)
The oncologist.
, vol.7
, pp. 288-323
-
-
Malet-Martino, M.1
Martino, R.2
-
82
-
-
73949117352
-
An epigenetic mechanism for capecitabine resistance in mesothelioma
-
Kosuri KV, Wu X, Wang L, Villalona-Calero MA and Otterson GA. An epigenetic mechanism for capecitabine resistance in mesothelioma. Biochemical and biophysical research communications. 2010; 391:1465-1470.
-
(2010)
Biochemical and biophysical research communications.
, vol.391
, pp. 1465-1470
-
-
Kosuri, K.V.1
Wu, X.2
Wang, L.3
Villalona-Calero, M.A.4
Otterson, G.A.5
-
83
-
-
81255162523
-
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands
-
O'Hagan HM, Wang W, Sen S, Destefano Shields C, Lee SS, Zhang YW, Clements EG, Cai Y, Van Neste L, Easwaran H, Casero RA, Sears CL and Baylin SB. Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands. Cancer cell. 2011; 20:606-619.
-
(2011)
Cancer cell.
, vol.20
, pp. 606-619
-
-
O'Hagan, H.M.1
Wang, W.2
Sen, S.3
Destefano Shields, C.4
Lee, S.S.5
Zhang, Y.W.6
Clements, E.G.7
Cai, Y.8
Van Neste, L.9
Easwaran, H.10
Casero, R.A.11
Sears, C.L.12
Baylin, S.B.13
-
84
-
-
34247869082
-
Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice
-
Yueh MF and Tukey RH. Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice. The Journal of biological chemistry. 2007; 282:8749-8758.
-
(2007)
The Journal of biological chemistry.
, vol.282
, pp. 8749-8758
-
-
Yueh, M.F.1
Tukey, R.H.2
-
85
-
-
77649322609
-
Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells
-
Belanger AS, Tojcic J, Harvey M and Guillemette C. Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells. BMC molecular biology. 2010; 11:9.
-
(2010)
BMC molecular biology.
, vol.11
, pp. 9
-
-
Belanger, A.S.1
Tojcic, J.2
Harvey, M.3
Guillemette, C.4
-
86
-
-
77649210559
-
Genotype-driven phase I study of irinotecan administered in combination with fluorouracil/leucovorin in patients with metastatic colorectal cancer
-
Toffoli G, Cecchin E, Gasparini G, D'Andrea M, Azzarello G, Basso U, Mini E, Pessa S, De Mattia E, Lo Re G, Buonadonna A, Nobili S, De Paoli P and Innocenti F. Genotype-driven phase I study of irinotecan administered in combination with fluorouracil/leucovorin in patients with metastatic colorectal cancer. Journal of clinical oncology. 2010; 28:866-871.
-
(2010)
Journal of clinical oncology.
, vol.28
, pp. 866-871
-
-
Toffoli, G.1
Cecchin, E.2
Gasparini, G.3
D'Andrea, M.4
Azzarello, G.5
Basso, U.6
Mini, E.7
Pessa, S.8
De Mattia, E.9
Lo Re, G.10
Buonadonna, A.11
Nobili, S.12
De Paoli, P.13
Innocenti, F.14
-
89
-
-
84920973485
-
Human mutations in methylenetetrahydrofolate dehydrogenase 1 impair nuclear de novo thymidylate biosynthesis
-
Field MS, Kamynina E, Watkins D, Rosenblatt DS and Stover PJ. Human mutations in methylenetetrahydrofolate dehydrogenase 1 impair nuclear de novo thymidylate biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 2015; 112:400- 405.
-
(2015)
Proceedings of the National Academy of Sciences of the United States of America.
, vol.112
, pp. 400- 405
-
-
Field, M.S.1
Kamynina, E.2
Watkins, D.3
Rosenblatt, D.S.4
Stover, P.J.5
-
90
-
-
0344875508
-
Role of cysteine amino acid residues on the RNA binding activity of human thymidylate synthase
-
Lin X, Liu J, Maley F and Chu E. Role of cysteine amino acid residues on the RNA binding activity of human thymidylate synthase. Nucleic acids research. 2003; 31:4882-4887.
-
(2003)
Nucleic acids research.
, vol.31
, pp. 4882-4887
-
-
Lin, X.1
Liu, J.2
Maley, F.3
Chu, E.4
-
91
-
-
77950801864
-
Identification of hypermethylated genes associated with cisplatin resistance in human cancers
-
Chang X, Monitto CL, Demokan S, Kim MS, Chang SS, Zhong X, Califano JA and Sidransky D. Identification of hypermethylated genes associated with cisplatin resistance in human cancers. Cancer research. 2010; 70:2870-2879.
-
(2010)
Cancer research.
, vol.70
, pp. 2870-2879
-
-
Chang, X.1
Monitto, C.L.2
Demokan, S.3
Kim, M.S.4
Chang, S.S.5
Zhong, X.6
Califano, J.A.7
Sidransky, D.8
-
92
-
-
34249321653
-
Mechanisms of resistance to cisplatin and carboplatin
-
Stewart DJ. Mechanisms of resistance to cisplatin and carboplatin. Critical reviews in oncology/hematology. 2007; 63:12-31.
-
(2007)
Critical reviews in oncology/hematology.
, vol.63
, pp. 12-31
-
-
Stewart, D.J.1
-
93
-
-
0034326784
-
Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter
-
Plumb JA, Strathdee G, Sludden J, Kaye SB and Brown R. Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter. Cancer research. 2000; 60:6039- 6044.
-
(2000)
Cancer research.
, vol.60
, pp. 6039- 6044
-
-
Plumb, J.A.1
Strathdee, G.2
Sludden, J.3
Kaye, S.B.4
Brown, R.5
-
94
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D and Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011; 144:646-674.
-
(2011)
Cell.
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
96
-
-
84856762901
-
Redox-based regulation of apoptosis: S-glutathionylation as a regulatory mechanism to control cell death
-
Anathy V, Roberson EC, Guala AS, Godburn KE, Budd RC and Janssen-Heininger YM. Redox-based regulation of apoptosis: S-glutathionylation as a regulatory mechanism to control cell death. Antioxidants & redox signaling. 2012; 16:496-505.
-
(2012)
Antioxidants & redox signaling.
, vol.16
, pp. 496-505
-
-
Anathy, V.1
Roberson, E.C.2
Guala, A.S.3
Godburn, K.E.4
Budd, R.C.5
Janssen-Heininger, Y.M.6
-
97
-
-
33846809031
-
Glutathiolation regulates tumor necrosis factor-alpha-induced caspase-3 cleavage and apoptosis: key role for glutaredoxin in the death pathway
-
Pan S and Berk BC. Glutathiolation regulates tumor necrosis factor-alpha-induced caspase-3 cleavage and apoptosis: key role for glutaredoxin in the death pathway. Circulation research. 2007; 100:213-219.
-
(2007)
Circulation research.
, vol.100
, pp. 213-219
-
-
Pan, S.1
Berk, B.C.2
-
98
-
-
33644818614
-
Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine
-
Mitchell DA and Marletta MA. Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine. Nature chemical biology. 2005; 1:154-158.
-
(2005)
Nature chemical biology.
, vol.1
, pp. 154-158
-
-
Mitchell, D.A.1
Marletta, M.A.2
-
99
-
-
0033597449
-
Fas-induced caspase denitrosylation
-
Mannick JB, Hausladen A, Liu L, Hess DT, Zeng M, Miao QX, Kane LS, Gow AJ and Stamler JS. Fas-induced caspase denitrosylation. Science. 1999; 284:651-654.
-
(1999)
Science.
, vol.284
, pp. 651-654
-
-
Mannick, J.B.1
Hausladen, A.2
Liu, L.3
Hess, D.T.4
Zeng, M.5
Miao, Q.X.6
Kane, L.S.7
Gow, A.J.8
Stamler, J.S.9
-
100
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO. The biochemistry of apoptosis. Nature. 2000; 407:770-776.
-
(2000)
Nature.
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
101
-
-
34247536682
-
The CD95 receptor: apoptosis revisited
-
Peter ME, Budd RC, Desbarats J, Hedrick SM, Hueber AO, Newell MK, Owen LB, Pope RM, Tschopp J, Wajant H, Wallach D, Wiltrout RH, Zornig M and Lynch DH. The CD95 receptor: apoptosis revisited. Cell. 2007; 129:447- 450.
-
(2007)
Cell.
, vol.129
, pp. 447- 450
-
-
Peter, M.E.1
Budd, R.C.2
Desbarats, J.3
Hedrick, S.M.4
Hueber, A.O.5
Newell, M.K.6
Owen, L.B.7
Pope, R.M.8
Tschopp, J.9
Wajant, H.10
Wallach, D.11
Wiltrout, R.H.12
Zornig, M.13
Lynch, D.H.14
-
102
-
-
49149130029
-
The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation
-
Wang L, Azad N, Kongkaneramit L, Chen F, Lu Y, Jiang BH and Rojanasakul Y. The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation. Journal of immunology. 2008; 180:3072-3080.
-
(2008)
Journal of immunology.
, vol.180
, pp. 3072-3080
-
-
Wang, L.1
Azad, N.2
Kongkaneramit, L.3
Chen, F.4
Lu, Y.5
Jiang, B.H.6
Rojanasakul, Y.7
-
103
-
-
84877627415
-
The role of c-FLIP in cisplatin resistance of human bladder cancer cells
-
Lee S, Yoon CY, Byun SS, Lee E and Lee SE. The role of c-FLIP in cisplatin resistance of human bladder cancer cells. The Journal of urology. 2013; 189:2327-2334.
-
(2013)
The Journal of urology.
, vol.189
, pp. 2327-2334
-
-
Lee, S.1
Yoon, C.Y.2
Byun, S.S.3
Lee, E.4
Lee, S.E.5
-
104
-
-
84896778773
-
Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer
-
Turkington RC, Longley DB, Allen WL, Stevenson L, McLaughlin K, Dunne PD, Blayney JK, Salto-Tellez M, Van Schaeybroeck S and Johnston PG. Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer. Cell Death Dis. 2014; 5:e1046.
-
(2014)
Cell Death Dis.
, vol.5
-
-
Turkington, R.C.1
Longley, D.B.2
Allen, W.L.3
Stevenson, L.4
McLaughlin, K.5
Dunne, P.D.6
Blayney, J.K.7
Salto-Tellez, M.8
Van Schaeybroeck, S.9
Johnston, P.G.10
-
105
-
-
58149330604
-
Combined inhibition of FLIP and XIAP induces Baxindependent apoptosis in type II colorectal cancer cells
-
Wilson TR, McEwan M, McLaughlin K, Le Clorennec C, Allen WL, Fennell DA, Johnston PG and Longley DB. Combined inhibition of FLIP and XIAP induces Baxindependent apoptosis in type II colorectal cancer cells. Oncogene. 2009; 28:63-72.
-
(2009)
Oncogene.
, vol.28
, pp. 63-72
-
-
Wilson, T.R.1
McEwan, M.2
McLaughlin, K.3
Le Clorennec, C.4
Allen, W.L.5
Fennell, D.A.6
Johnston, P.G.7
Longley, D.B.8
-
106
-
-
65949102791
-
Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress
-
Kopetz S, Lesslie DP, Dallas NA, Park SI, Johnson M, Parikh NU, Kim MP, Abbruzzese JL, Ellis LM, Chandra J and Gallick GE. Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress. Cancer research. 2009; 69:3842-3849.
-
(2009)
Cancer research.
, vol.69
, pp. 3842-3849
-
-
Kopetz, S.1
Lesslie, D.P.2
Dallas, N.A.3
Park, S.I.4
Johnson, M.5
Parikh, N.U.6
Kim, M.P.7
Abbruzzese, J.L.8
Ellis, L.M.9
Chandra, J.10
Gallick, G.E.11
-
107
-
-
78650831662
-
DAMP-mediated autophagy contributes to drug resistance
-
Liu L, Yang M, Kang R, Wang Z, Zhao Y, Yu Y, Xie M, Yin X, Livesey KM, Loze MT, Tang D and Cao L. DAMP-mediated autophagy contributes to drug resistance. Autophagy. 2011; 7:112-114.
-
(2011)
Autophagy.
, vol.7
, pp. 112-114
-
-
Liu, L.1
Yang, M.2
Kang, R.3
Wang, Z.4
Zhao, Y.5
Yu, Y.6
Xie, M.7
Yin, X.8
Livesey, K.M.9
Loze, M.T.10
Tang, D.11
Cao, L.12
-
108
-
-
0033062872
-
Induction of CD95 ligand and apoptosis by doxorubicin is modulated by the redox state in chemosensitive- and drug-resistant tumor cells
-
Friesen C, Fulda S and Debatin KM. Induction of CD95 ligand and apoptosis by doxorubicin is modulated by the redox state in chemosensitive- and drug-resistant tumor cells. Cell death and differentiation. 1999; 6:471-480.
-
(1999)
Cell death and differentiation.
, vol.6
, pp. 471-480
-
-
Friesen, C.1
Fulda, S.2
Debatin, K.M.3
-
109
-
-
0029561598
-
The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
-
Hayes JD and Pulford DJ. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Critical reviews in biochemistry and molecular biology. 1995; 30:445-600.
-
(1995)
Critical reviews in biochemistry and molecular biology.
, vol.30
, pp. 445-600
-
-
Hayes, J.D.1
Pulford, D.J.2
-
110
-
-
84877323041
-
Autophagy and ER stress play an essential role in the mechanism of action and drug resistance of the cyclin-dependent kinase inhibitor flavopiridol
-
T Mahoney E, Byrd JC and Johnson AJ. Autophagy and ER stress play an essential role in the mechanism of action and drug resistance of the cyclin-dependent kinase inhibitor flavopiridol. Autophagy. 2013; 9:434-435.
-
(2013)
Autophagy.
, vol.9
, pp. 434-435
-
-
Mahoney, E.1
Byrd, J.C.2
Johnson, A.J.3
-
112
-
-
77954382142
-
Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation
-
Wu RF, Ma Z, Liu Z and Terada LS. Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation. Molecular and cellular biology. 2010; 30:3553- 3568.
-
(2010)
Molecular and cellular biology.
, vol.30
, pp. 3553- 3568
-
-
Wu, R.F.1
Ma, Z.2
Liu, Z.3
Terada, L.S.4
-
113
-
-
34247186472
-
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
-
Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L and Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. The EMBO journal. 2007; 26:1749-1760.
-
(2007)
The EMBO journal.
, vol.26
, pp. 1749-1760
-
-
Scherz-Shouval, R.1
Shvets, E.2
Fass, E.3
Shorer, H.4
Gil, L.5
Elazar, Z.6
-
114
-
-
58149086894
-
Dihydrocapsaicin (DHC), a saturated structural analog of capsaicin, induces autophagy in human cancer cells in a catalase-regulated manner
-
Oh SH, Kim YS, Lim SC, Hou YF, Chang IY and You HJ. Dihydrocapsaicin (DHC), a saturated structural analog of capsaicin, induces autophagy in human cancer cells in a catalase-regulated manner. Autophagy. 2008; 4:1009-1019.
-
(2008)
Autophagy.
, vol.4
, pp. 1009-1019
-
-
Oh, S.H.1
Kim, Y.S.2
Lim, S.C.3
Hou, Y.F.4
Chang, I.Y.5
You, H.J.6
-
115
-
-
77953541592
-
Selective induction of catalase-mediated autophagy by dihydrocapsaicin in lung cell lines
-
Choi CH, Jung YK and Oh SH. Selective induction of catalase-mediated autophagy by dihydrocapsaicin in lung cell lines. Free radical biology & medicine. 2010; 49:245- 257.
-
(2010)
Free radical biology & medicine.
, vol.49
, pp. 245- 257
-
-
Choi, C.H.1
Jung, Y.K.2
Oh, S.H.3
-
116
-
-
34447636066
-
Functional genomic approach to identify novel genes involved in the regulation of oxidative stress resistance and animal lifespan
-
Kim Y and Sun H. Functional genomic approach to identify novel genes involved in the regulation of oxidative stress resistance and animal lifespan. Aging cell. 2007; 6:489-503.
-
(2007)
Aging cell.
, vol.6
, pp. 489-503
-
-
Kim, Y.1
Sun, H.2
-
117
-
-
84866358168
-
The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance
-
Bouwman P and Jonkers J. The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance. Nature reviews Cancer. 2012; 12:587-598.
-
(2012)
Nature reviews Cancer.
, vol.12
, pp. 587-598
-
-
Bouwman, P.1
Jonkers, J.2
-
118
-
-
0031424866
-
Induction and repair inhibition of oxidative DNA damage by nickel(II) and cadmium(II) in mammalian cells
-
Dally H and Hartwig A. Induction and repair inhibition of oxidative DNA damage by nickel(II) and cadmium(II) in mammalian cells. Carcinogenesis. 1997; 18:1021-1026.
-
(1997)
Carcinogenesis.
, vol.18
, pp. 1021-1026
-
-
Dally, H.1
Hartwig, A.2
-
119
-
-
33749593461
-
Redox regulation of human OGG1 activity in response to cellular oxidative stress
-
Bravard A, Vacher M, Gouget B, Coutant A, de Boisferon FH, Marsin S, Chevillard S and Radicella JP. Redox regulation of human OGG1 activity in response to cellular oxidative stress. Molecular and cellular biology. 2006; 26:7430-7436.
-
(2006)
Molecular and cellular biology.
, vol.26
, pp. 7430-7436
-
-
Bravard, A.1
Vacher, M.2
Gouget, B.3
Coutant, A.4
de Boisferon, F.H.5
Marsin, S.6
Chevillard, S.7
Radicella, J.P.8
-
120
-
-
84455161816
-
Poly(ADP-ribose) polymerase 1 (PARP-1) binds to 8-oxoguanine-DNA glycosylase (OGG1)
-
Noren Hooten N, Kompaniez K, Barnes J, Lohani A and Evans MK. Poly(ADP-ribose) polymerase 1 (PARP-1) binds to 8-oxoguanine-DNA glycosylase (OGG1). The Journal of biological chemistry. 2011; 286:44679-44690.
-
(2011)
The Journal of biological chemistry.
, vol.286
, pp. 44679-44690
-
-
Noren Hooten, N.1
Kompaniez, K.2
Barnes, J.3
Lohani, A.4
Evans, M.K.5
-
121
-
-
35348971904
-
Stimulation of NEIL2- mediated oxidized base excision repair via YB-1 interaction during oxidative stress
-
Das S, Chattopadhyay R, Bhakat KK, Boldogh I, Kohno K, Prasad R, Wilson SH and Hazra TK. Stimulation of NEIL2- mediated oxidized base excision repair via YB-1 interaction during oxidative stress. The Journal of biological chemistry. 2007; 282:28474-28484.
-
(2007)
The Journal of biological chemistry.
, vol.282
, pp. 28474-28484
-
-
Das, S.1
Chattopadhyay, R.2
Bhakat, K.K.3
Boldogh, I.4
Kohno, K.5
Prasad, R.6
Wilson, S.H.7
Hazra, T.K.8
-
123
-
-
84855822330
-
APE1/Ref-role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1
-
Kelley MR, Georgiadis MM and Fishel ML. APE1/Ref-role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1. Current molecular pharmacology. 2012; 5:36-53.
-
(2012)
Current molecular pharmacology.
, vol.5
, pp. 36-53
-
-
Kelley, M.R.1
Georgiadis, M.M.2
Fishel, M.L.3
-
124
-
-
51349134457
-
Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1
-
Luo M, Delaplane S, Jiang A, Reed A, He Y, Fishel M, Nyland RL, 2nd, Borch RF, Qiao X, Georgiadis MM and Kelley MR. Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1. Antioxidants & redox signaling. 2008; 10:1853-1867.
-
(2008)
Antioxidants & redox signaling.
, vol.10
, pp. 1853-1867
-
-
Luo, M.1
Delaplane, S.2
Jiang, A.3
Reed, A.4
He, Y.5
Fishel, M.6
Nyland, R.L.7
Borch, R.F.8
Qiao, X.9
Georgiadis, M.M.10
Kelley, M.R.11
-
126
-
-
77954983910
-
Radiation resistance in glioma cells determined by DNA damage repair activity of Ape1/Ref-1
-
Naidu MD, Mason JM, Pica RV, Fung H and Pena LA. Radiation resistance in glioma cells determined by DNA damage repair activity of Ape1/Ref-1. Journal of radiation research. 2010; 51:393-404.
-
(2010)
Journal of radiation research.
, vol.51
, pp. 393-404
-
-
Naidu, M.D.1
Mason, J.M.2
Pica, R.V.3
Fung, H.4
Pena, L.A.5
-
127
-
-
0036718792
-
The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress
-
Silber JR, Bobola MS, Blank A, Schoeler KD, Haroldson PD, Huynh MB and Kolstoe DD. The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress. Clinical cancer research. 2002; 8:3008- 3018.
-
(2002)
Clinical cancer research.
, vol.8
, pp. 3008- 3018
-
-
Silber, J.R.1
Bobola, M.S.2
Blank, A.3
Schoeler, K.D.4
Haroldson, P.D.5
Huynh, M.B.6
Kolstoe, D.D.7
-
128
-
-
80052967569
-
Apurinic/ apyrimidinic endonuclease is inversely associated with response to radiotherapy in pediatric ependymoma
-
Bobola MS, Jankowski PP, Gross ME, Schwartz J, Finn LS, Blank A, Ellenbogen RG and Silber JR. Apurinic/ apyrimidinic endonuclease is inversely associated with response to radiotherapy in pediatric ependymoma. International journal of cancer. 2011; 129:2370-2379.
-
(2011)
International journal of cancer.
, vol.129
, pp. 2370-2379
-
-
Bobola, M.S.1
Jankowski, P.P.2
Gross, M.E.3
Schwartz, J.4
Finn, L.S.5
Blank, A.6
Ellenbogen, R.G.7
Silber, J.R.8
-
129
-
-
84874718458
-
Downregulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 enhances the sensitivity of human pancreatic cancer cells to radiotherapy in vitro
-
Chen S, Xiong G, Wu S and Mo J. Downregulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 enhances the sensitivity of human pancreatic cancer cells to radiotherapy in vitro. Cancer biotherapy & radiopharmaceuticals. 2013; 28:169-176.
-
(2013)
Cancer biotherapy & radiopharmaceuticals.
, vol.28
, pp. 169-176
-
-
Chen, S.1
Xiong, G.2
Wu, S.3
Mo, J.4
-
130
-
-
0032574770
-
Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals
-
Ramana CV, Boldogh I, Izumi T and Mitra S. Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals. Proceedings of the National Academy of Sciences of the United States of America. 1998; 95:5061-5066.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America.
, vol.95
, pp. 5061-5066
-
-
Ramana, C.V.1
Boldogh, I.2
Izumi, T.3
Mitra, S.4
-
131
-
-
23344435521
-
Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
-
Pines A, Perrone L, Bivi N, Romanello M, Damante G, Gulisano M, Kelley MR, Quadrifoglio F and Tell G. Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP. Nucleic acids research. 2005; 33:4379-4394.
-
(2005)
Nucleic acids research.
, vol.33
, pp. 4379-4394
-
-
Pines, A.1
Perrone, L.2
Bivi, N.3
Romanello, M.4
Damante, G.5
Gulisano, M.6
Kelley, M.R.7
Quadrifoglio, F.8
Tell, G.9
-
132
-
-
0035879047
-
Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation
-
Hsieh MM, Hegde V, Kelley MR and Deutsch WA. Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation. Nucleic acids research. 2001; 29:3116-3122.
-
(2001)
Nucleic acids research.
, vol.29
, pp. 3116-3122
-
-
Hsieh, M.M.1
Hegde, V.2
Kelley, M.R.3
Deutsch, W.A.4
-
134
-
-
15844394846
-
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
-
Falck J, Coates J and Jackson SP. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature. 2005; 434:605-611.
-
(2005)
Nature.
, vol.434
, pp. 605-611
-
-
Falck, J.1
Coates, J.2
Jackson, S.P.3
-
135
-
-
33744948987
-
Kinetic analysis of the Ku-DNA binding activity reveals a redox-dependent alteration in protein structure that stimulates dissociation of the Ku-DNA complex
-
Andrews BJ, Lehman JA and Turchi JJ. Kinetic analysis of the Ku-DNA binding activity reveals a redox-dependent alteration in protein structure that stimulates dissociation of the Ku-DNA complex. The Journal of biological chemistry. 2006; 281:13596-13603.
-
(2006)
The Journal of biological chemistry.
, vol.281
, pp. 13596-13603
-
-
Andrews, B.J.1
Lehman, J.A.2
Turchi, J.J.3
-
136
-
-
0037155915
-
Mutation in the glucose-6- phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress
-
Ayene IS, Stamato TD, Mauldin SK, Biaglow JE, Tuttle SW, Jenkins SF and Koch CJ. Mutation in the glucose-6- phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress. The Journal of biological chemistry. 2002; 277:9929-9935.
-
(2002)
The Journal of biological chemistry.
, vol.277
, pp. 9929-9935
-
-
Ayene, I.S.1
Stamato, T.D.2
Mauldin, S.K.3
Biaglow, J.E.4
Tuttle, S.W.5
Jenkins, S.F.6
Koch, C.J.7
-
137
-
-
79551580561
-
ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair
-
Cosentino C, Grieco D and Costanzo V. ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair. The EMBO journal. 2011; 30:546-555.
-
(2011)
The EMBO journal.
, vol.30
, pp. 546-555
-
-
Cosentino, C.1
Grieco, D.2
Costanzo, V.3
-
139
-
-
84876444486
-
Thioredoxin-mediated redox regulation of resistance to endocrine therapy in breast cancer
-
Penney RB and Roy D. Thioredoxin-mediated redox regulation of resistance to endocrine therapy in breast cancer. Biochimica et biophysica acta. 2013; 1836:60-79.
-
(2013)
Biochimica et biophysica acta.
, vol.1836
, pp. 60-79
-
-
Penney, R.B.1
Roy, D.2
-
140
-
-
0032588748
-
O6-methylguanine-DNA methyltransferasedeficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy
-
Silber JR, Blank A, Bobola MS, Ghatan S, Kolstoe DD and Berger MS. O6-methylguanine-DNA methyltransferasedeficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy. Clinical cancer research. 1999; 5:807-814.
-
(1999)
Clinical cancer research.
, vol.5
, pp. 807-814
-
-
Silber, J.R.1
Blank, A.2
Bobola, M.S.3
Ghatan, S.4
Kolstoe, D.D.5
Berger, M.S.6
-
141
-
-
84856233300
-
Balancing repair and tolerance of DNA damage caused by alkylating agents
-
Fu D, Calvo JA and Samson LD. Balancing repair and tolerance of DNA damage caused by alkylating agents. Nature reviews Cancer. 2012; 12:104-120.
-
(2012)
Nature reviews Cancer.
, vol.12
, pp. 104-120
-
-
Fu, D.1
Calvo, J.A.2
Samson, L.D.3
-
142
-
-
84862835220
-
Drug resistance in glioblastoma: a mini review
-
Haar CP, Hebbar P, Wallace GCt, Das A, Vandergrift WA, 3rd, Smith JA, Giglio P, Patel SJ, Ray SK and Banik NL. Drug resistance in glioblastoma: a mini review. Neurochemical research. 2012; 37:1192-1200.
-
(2012)
Neurochemical research.
, vol.37
, pp. 1192-1200
-
-
Haar, C.P.1
Hebbar, P.2
Wallace, G.C.3
Das, A.4
Vandergrift, W.A.5
Smith, J.A.6
Giglio, P.7
Patel, S.J.8
Ray, S.K.9
Banik, N.L.10
-
143
-
-
31544464704
-
Targeted modulation of MGMT: clinical implications
-
Liu L and Gerson SL. Targeted modulation of MGMT: clinical implications. Clinical cancer research. 2006; 12:328-331.
-
(2006)
Clinical cancer research.
, vol.12
, pp. 328-331
-
-
Liu, L.1
Gerson, S.L.2
-
144
-
-
84908251818
-
Poised epigenetic states and acquired drug resistance in cancer
-
Brown R, Curry E, Magnani L, Wilhelm-Benartzi CS and Borley J. Poised epigenetic states and acquired drug resistance in cancer. Nature reviews Cancer. 2014; 14:747- 753.
-
(2014)
Nature reviews Cancer.
, vol.14
, pp. 747- 753
-
-
Brown, R.1
Curry, E.2
Magnani, L.3
Wilhelm-Benartzi, C.S.4
Borley, J.5
-
146
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, Hamou MF, de Tribolet N, Weller M, Kros JM, Hainfellner JA, Mason W, Mariani L, Bromberg JE, Hau P, Mirimanoff RO, Cairncross JG, Janzer RC and Stupp R. MGMT gene silencing and benefit from temozolomide in glioblastoma. The New England journal of medicine. 2005; 352:997-1003.
-
(2005)
The New England journal of medicine.
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
Hamou, M.F.4
de Tribolet, N.5
Weller, M.6
Kros, J.M.7
Hainfellner, J.A.8
Mason, W.9
Mariani, L.10
Bromberg, J.E.11
Hau, P.12
Mirimanoff, R.O.13
Cairncross, J.G.14
Janzer, R.C.15
Stupp, R.16
-
147
-
-
33745263216
-
Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice
-
Reliene R and Schiestl RH. Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice. DNA repair. 2006; 5:852-859.
-
(2006)
DNA repair.
, vol.5
, pp. 852-859
-
-
Reliene, R.1
Schiestl, R.H.2
-
148
-
-
28644447272
-
The antioxidant function of the p53 tumor suppressor
-
Sablina AA, Budanov AV, Ilyinskaya GV, Agapova LS, Kravchenko JE and Chumakov PM. The antioxidant function of the p53 tumor suppressor. Nature medicine. 2005; 11:1306-1313.
-
(2005)
Nature medicine.
, vol.11
, pp. 1306-1313
-
-
Sablina, A.A.1
Budanov, A.V.2
Ilyinskaya, G.V.3
Agapova, L.S.4
Kravchenko, J.E.5
Chumakov, P.M.6
-
149
-
-
34548257176
-
HIF-dependent antitumorigenic effect of antioxidants in vivo
-
Gao P, Zhang H, Dinavahi R, Li F, Xiang Y, Raman V, Bhujwalla ZM, Felsher DW, Cheng L, Pevsner J, Lee LA, Semenza GL and Dang CV. HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer cell. 2007; 12:230- 238.
-
(2007)
Cancer cell.
, vol.12
, pp. 230- 238
-
-
Gao, P.1
Zhang, H.2
Dinavahi, R.3
Li, F.4
Xiang, Y.5
Raman, V.6
Bhujwalla, Z.M.7
Felsher, D.W.8
Cheng, L.9
Pevsner, J.10
Lee, L.A.11
Semenza, G.L.12
Dang, C.V.13
-
150
-
-
80053954605
-
Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
-
Klein EA, Thompson IM, Jr., Tangen CM, Crowley JJ, Lucia MS, Goodman PJ, Minasian LM, Ford LG, Parnes HL, Gaziano JM, Karp DD, Lieber MM, Walther PJ, Klotz L, Parsons JK, Chin JL, et al. Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). Jama. 2011; 306:1549-1556.
-
(2011)
Jama.
, vol.306
, pp. 1549-1556
-
-
Klein, E.A.1
Thompson, I.M.2
Tangen, C.M.3
Crowley, J.J.4
Lucia, M.S.5
Goodman, P.J.6
Minasian, L.M.7
Ford, L.G.8
Parnes, H.L.9
Gaziano, J.M.10
Karp, D.D.11
Lieber, M.M.12
Walther, P.J.13
Klotz, L.14
Parsons, J.K.15
Chin, J.L.16
-
151
-
-
9244262406
-
Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease
-
Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A, Keogh JP, Meyskens FL, Valanis B, Williams JH, Barnhart S and Hammar S. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. The New England journal of medicine. 1996; 334:1150-1155.
-
(1996)
The New England journal of medicine.
, vol.334
, pp. 1150-1155
-
-
Omenn, G.S.1
Goodman, G.E.2
Thornquist, M.D.3
Balmes, J.4
Cullen, M.R.5
Glass, A.6
Keogh, J.P.7
Meyskens, F.L.8
Valanis, B.9
Williams, J.H.10
Barnhart, S.11
Hammar, S.12
-
152
-
-
84946903513
-
Oxidative stress inhibits distant metastasis by human melanoma cells
-
Piskounova E, Agathocleous M, Murphy MM, Hu Z, Huddlestun SE, Zhao Z, Leitch AM, Johnson TM, DeBerardinis RJ and Morrison SJ. Oxidative stress inhibits distant metastasis by human melanoma cells. Nature. 2015; 527:186-191.
-
(2015)
Nature.
, vol.527
, pp. 186-191
-
-
Piskounova, E.1
Agathocleous, M.2
Murphy, M.M.3
Hu, Z.4
Huddlestun, S.E.5
Zhao, Z.6
Leitch, A.M.7
Johnson, T.M.8
DeBerardinis, R.J.9
Morrison, S.J.10
-
153
-
-
84943639915
-
Antioxidants can increase melanoma metastasis in mice
-
Le Gal K, Ibrahim MX, Wiel C, Sayin VI, Akula MK, Karlsson C, Dalin MG, Akyurek LM, Lindahl P, Nilsson J and Bergo MO. Antioxidants can increase melanoma metastasis in mice. Science translational medicine. 2015; 7:308re308.
-
(2015)
Science translational medicine.
, vol.7
-
-
Le Gal, K.1
Ibrahim, M.X.2
Wiel, C.3
Sayin, V.I.4
Akula, M.K.5
Karlsson, C.6
Dalin, M.G.7
Akyurek, L.M.8
Lindahl, P.9
Nilsson, J.10
Bergo, M.O.11
-
154
-
-
0028797079
-
Resistance to oxidants associated with elevated catalase activity in HL-60 leukemia cells that overexpress multidrug-resistance protein does not contribute to the resistance to daunorubicin manifested by these cells
-
Lenehan PF, Gutierrez PL, Wagner JL, Milak N, Fisher GR and Ross DD. Resistance to oxidants associated with elevated catalase activity in HL-60 leukemia cells that overexpress multidrug-resistance protein does not contribute to the resistance to daunorubicin manifested by these cells. Cancer chemotherapy and pharmacology. 1995; 35:377-386.
-
(1995)
Cancer chemotherapy and pharmacology.
, vol.35
, pp. 377-386
-
-
Lenehan, P.F.1
Gutierrez, P.L.2
Wagner, J.L.3
Milak, N.4
Fisher, G.R.5
Ross, D.D.6
-
155
-
-
14844310296
-
Changes in gene expression profiles of multiple myeloma cells induced by arsenic trioxide (ATO): possible mechanisms to explain ATO resistance in vivo
-
Zhou P, Kalakonda N and Comenzo RL. Changes in gene expression profiles of multiple myeloma cells induced by arsenic trioxide (ATO): possible mechanisms to explain ATO resistance in vivo. British journal of haematology. 2005; 128:636-644.
-
(2005)
British journal of haematology.
, vol.128
, pp. 636-644
-
-
Zhou, P.1
Kalakonda, N.2
Comenzo, R.L.3
-
156
-
-
24944486664
-
Resistance to paclitaxel is proportional to cellular total antioxidant capacity
-
Ramanathan B, Jan KY, Chen CH, Hour TC, Yu HJ and Pu YS. Resistance to paclitaxel is proportional to cellular total antioxidant capacity. Cancer research. 2005; 65:8455-8460.
-
(2005)
Cancer research.
, vol.65
, pp. 8455-8460
-
-
Ramanathan, B.1
Jan, K.Y.2
Chen, C.H.3
Hour, T.C.4
Yu, H.J.5
Pu, Y.S.6
-
157
-
-
34248183395
-
Gene expressions associated with chemosensitivity in human hepatoma cells
-
Hoshida Y, Moriyama M, Otsuka M, Kato N, Taniguchi H, Shiratori Y, Seki N and Omata M. Gene expressions associated with chemosensitivity in human hepatoma cells. Hepato-gastroenterology. 2007; 54:489-492.
-
(2007)
Hepato-gastroenterology.
, vol.54
, pp. 489-492
-
-
Hoshida, Y.1
Moriyama, M.2
Otsuka, M.3
Kato, N.4
Taniguchi, H.5
Shiratori, Y.6
Seki, N.7
Omata, M.8
-
158
-
-
0037926836
-
Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents
-
Zhou Y, Hileman EO, Plunkett W, Keating MJ and Huang P. Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents. Blood. 2003; 101:4098-4104.
-
(2003)
Blood.
, vol.101
, pp. 4098-4104
-
-
Zhou, Y.1
Hileman, E.O.2
Plunkett, W.3
Keating, M.J.4
Huang, P.5
-
159
-
-
0036896388
-
Feasibility and correlates of arsenic trioxide combined with ascorbic acidmediated depletion of intracellular glutathione for the treatment of relapsed/refractory multiple myeloma
-
Bahlis NJ, McCafferty-Grad J, Jordan-McMurry I, Neil J, Reis I, Kharfan-Dabaja M, Eckman J, Goodman M, Fernandez HF, Boise LH and Lee KP. Feasibility and correlates of arsenic trioxide combined with ascorbic acidmediated depletion of intracellular glutathione for the treatment of relapsed/refractory multiple myeloma. Clinical cancer research. 2002; 8:3658-3668.
-
(2002)
Clinical cancer research.
, vol.8
, pp. 3658-3668
-
-
Bahlis, N.J.1
McCafferty-Grad, J.2
Jordan-McMurry, I.3
Neil, J.4
Reis, I.5
Kharfan-Dabaja, M.6
Eckman, J.7
Goodman, M.8
Fernandez, H.F.9
Boise, L.H.10
Lee, K.P.11
-
160
-
-
84863069814
-
Mitochondrial dysfunction, a probable cause of persistent oxidative stress after exposure to ionizing radiation
-
Yoshida T, Goto S, Kawakatsu M, Urata Y and Li TS. Mitochondrial dysfunction, a probable cause of persistent oxidative stress after exposure to ionizing radiation. Free radical research. 2012; 46:147-153.
-
(2012)
Free radical research.
, vol.46
, pp. 147-153
-
-
Yoshida, T.1
Goto, S.2
Kawakatsu, M.3
Urata, Y.4
Li, T.S.5
-
161
-
-
84902208618
-
Estrogen-related receptor alpha confers methotrexate resistance via attenuation of reactive oxygen species production and P53 mediated apoptosis in osteosarcoma cells
-
Chen P, Wang H, Duan Z, Zou JX, Chen H, He W and Wang J. Estrogen-related receptor alpha confers methotrexate resistance via attenuation of reactive oxygen species production and P53 mediated apoptosis in osteosarcoma cells. BioMed research international. 2014; 2014:616025.
-
(2014)
BioMed research international.
, vol.2014
, pp. 616025
-
-
Chen, P.1
Wang, H.2
Duan, Z.3
Zou, J.X.4
Chen, H.5
He, W.6
Wang, J.7
-
163
-
-
84894094517
-
Premature senescence in human breast cancer and colon cancer cells by tamoxifenmediated reactive oxygen species generation
-
Lee YH, Kang BS and Bae YS. Premature senescence in human breast cancer and colon cancer cells by tamoxifenmediated reactive oxygen species generation. Life sciences. 2014; 97:116-122.
-
(2014)
Life sciences.
, vol.97
, pp. 116-122
-
-
Lee, Y.H.1
Kang, B.S.2
Bae, Y.S.3
-
164
-
-
84894184722
-
Cisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functions
-
Marullo R, Werner E, Degtyareva N, Moore B, Altavilla G, Ramalingam SS and Doetsch PW. Cisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functions. PloS one. 2013; 8:e81162.
-
(2013)
PloS one.
, vol.8
-
-
Marullo, R.1
Werner, E.2
Degtyareva, N.3
Moore, B.4
Altavilla, G.5
Ramalingam, S.S.6
Doetsch, P.W.7
-
165
-
-
84938206788
-
Lentinan exerts synergistic apoptotic effects with paclitaxel in A549 cells via activating ROS-TXNIP-NLRP3 inflammasome
-
Liu W, Gu J, Qi J, Zeng XN, Ji J, Chen ZZ and Sun XL. Lentinan exerts synergistic apoptotic effects with paclitaxel in A549 cells via activating ROS-TXNIP-NLRP3 inflammasome. Journal of cellular and molecular medicine. 2015; 19:1949-55.
-
(2015)
Journal of cellular and molecular medicine.
, vol.19
, pp. 1949-1955
-
-
Liu, W.1
Gu, J.2
Qi, J.3
Zeng, X.N.4
Ji, J.5
Chen, Z.Z.6
Sun, X.L.7
-
166
-
-
84901236437
-
Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling
-
Fan C, Zheng W, Fu X, Li X, Wong YS and Chen T. Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling. Oncotarget. 2014; 5:2853-2863. doi: 10.18632/ oncotarget.1854.
-
(2014)
Oncotarget.
, vol.5
, pp. 2853-2863
-
-
Fan, C.1
Zheng, W.2
Fu, X.3
Li, X.4
Wong, Y.S.5
Chen, T.6
-
167
-
-
84876712355
-
Nuclear translocation of heme oxygenase-1 confers resistance to imatinib in chronic myeloid leukemia cells
-
Tibullo D, Barbagallo I, Giallongo C, La Cava P, Parrinello N, Vanella L, Stagno F, Palumbo GA, Li Volti G and Di Raimondo F. Nuclear translocation of heme oxygenase-1 confers resistance to imatinib in chronic myeloid leukemia cells. Current pharmaceutical design. 2013; 19:2765-2770.
-
(2013)
Current pharmaceutical design.
, vol.19
, pp. 2765-2770
-
-
Tibullo, D.1
Barbagallo, I.2
Giallongo, C.3
La Cava, P.4
Parrinello, N.5
Vanella, L.6
Stagno, F.7
Palumbo, G.A.8
Li Volti, G.9
Di Raimondo, F.10
-
168
-
-
84909585862
-
Camptothecin sensitizes human hepatoma Hep3B cells to TRAIL-mediated apoptosis via ROS-dependent death receptor 5 upregulation with the involvement of MAPKs
-
Jayasooriya RG, Choi YH, Hyun JW and Kim GY. Camptothecin sensitizes human hepatoma Hep3B cells to TRAIL-mediated apoptosis via ROS-dependent death receptor 5 upregulation with the involvement of MAPKs. Environmental toxicology and pharmacology. 2014; 38:959-967.
-
(2014)
Environmental toxicology and pharmacology.
, vol.38
, pp. 959-967
-
-
Jayasooriya, R.G.1
Choi, Y.H.2
Hyun, J.W.3
Kim, G.Y.4
-
169
-
-
50449108847
-
Combinatorial antileukemic disruption of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide 2-(2,4-difluoro-phenyl)-4,5,6,7- tetrafluoro-1H-isoindole-1,3(2H)-dione (CPS49) and flavopiridol
-
Ge Y, Byun JS, De Luca P, Gueron G, Yabe IM, Sadiq-Ali SG, Figg WD, Quintero J, Haggerty CM, Li QQ, De Siervi A and Gardner K. Combinatorial antileukemic disruption of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide 2-(2,4-difluoro-phenyl)-4,5,6,7- tetrafluoro-1H-isoindole-1,3(2H)-dione (CPS49) and flavopiridol. Molecular pharmacology. 2008; 74:872-883.
-
(2008)
Molecular pharmacology.
, vol.74
, pp. 872-883
-
-
Ge, Y.1
Byun, J.S.2
De Luca, P.3
Gueron, G.4
Yabe, I.M.5
Sadiq-Ali, S.G.6
Figg, W.D.7
Quintero, J.8
Haggerty, C.M.9
Li, Q.Q.10
De Siervi, A.11
Gardner, K.12
-
170
-
-
84900838270
-
Protein oxidation and DNA repair inhibition by 6-thioguanine and UVA radiation
-
Gueranger Q, Li F, Peacock M, Larnicol-Fery A, Brem R, Macpherson P, Egly JM and Karran P. Protein oxidation and DNA repair inhibition by 6-thioguanine and UVA radiation. The Journal of investigative dermatology. 2014; 134:1408-1417.
-
(2014)
The Journal of investigative dermatology.
, vol.134
, pp. 1408-1417
-
-
Gueranger, Q.1
Li, F.2
Peacock, M.3
Larnicol-Fery, A.4
Brem, R.5
Macpherson, P.6
Egly, J.M.7
Karran, P.8
-
171
-
-
58149105356
-
Cancer cell killing via ROS: to increase or decrease, that is the question
-
Wang J and Yi J. Cancer cell killing via ROS: to increase or decrease, that is the question. Cancer biology & therapy. 2008; 7:1875-1884.
-
(2008)
Cancer biology & therapy.
, vol.7
, pp. 1875-1884
-
-
Wang, J.1
Yi, J.2
-
172
-
-
84857916510
-
Phase 2 study of neoadjuvant treatment with NOV-002 in combination with doxorubicin and cyclophosphamide followed by docetaxel in patients with HER-2 negative clinical stage II-IIIc breast cancer
-
Montero AJ, Diaz-Montero CM, Deutsch YE, Hurley J, Koniaris LG, Rumboldt T, Yasir S, Jorda M, Garret-Mayer E, Avisar E, Slingerland J, Silva O, Welsh C, Schuhwerk K, Seo P, Pegram MD, et al. Phase 2 study of neoadjuvant treatment with NOV-002 in combination with doxorubicin and cyclophosphamide followed by docetaxel in patients with HER-2 negative clinical stage II-IIIc breast cancer. Breast cancer research and treatment. 2012; 132:215-223.
-
(2012)
Breast cancer research and treatment.
, vol.132
, pp. 215-223
-
-
Montero, A.J.1
Diaz-Montero, C.M.2
Deutsch, Y.E.3
Hurley, J.4
Koniaris, L.G.5
Rumboldt, T.6
Yasir, S.7
Jorda, M.8
Garret-Mayer, E.9
Avisar, E.10
Slingerland, J.11
Silva, O.12
Welsh, C.13
Schuhwerk, K.14
Seo, P.15
Pegram, M.D.16
-
173
-
-
77953117152
-
Potential use of the anti-inflammatory drug, sulfasalazine, for targeted therapy of pancreatic cancer
-
Lo M, Ling V, Low C, Wang YZ and Gout PW. Potential use of the anti-inflammatory drug, sulfasalazine, for targeted therapy of pancreatic cancer. Current oncology. 2010; 17:9-16.
-
(2010)
Current oncology.
, vol.17
, pp. 9-16
-
-
Lo, M.1
Ling, V.2
Low, C.3
Wang, Y.Z.4
Gout, P.W.5
-
174
-
-
67349136816
-
The xc- cystine/ glutamate antiporter as a potential therapeutic target for small-cell lung cancer: use of sulfasalazine
-
Guan J, Lo M, Dockery P, Mahon S, Karp CM, Buckley AR, Lam S, Gout PW and Wang YZ. The xc- cystine/ glutamate antiporter as a potential therapeutic target for small-cell lung cancer: use of sulfasalazine. Cancer chemotherapy and pharmacology. 2009; 64:463-472.
-
(2009)
Cancer chemotherapy and pharmacology.
, vol.64
, pp. 463-472
-
-
Guan, J.1
Lo, M.2
Dockery, P.3
Mahon, S.4
Karp, C.M.5
Buckley, A.R.6
Lam, S.7
Gout, P.W.8
Wang, Y.Z.9
-
175
-
-
84863989495
-
Pancreatic tumor sensitivity to plasma L-asparagine starvation
-
Dufour E, Gay F, Aguera K, Scoazec JY, Horand F, Lorenzi PL and Godfrin Y. Pancreatic tumor sensitivity to plasma L-asparagine starvation. Pancreas. 2012; 41:940-948.
-
(2012)
Pancreas.
, vol.41
, pp. 940-948
-
-
Dufour, E.1
Gay, F.2
Aguera, K.3
Scoazec, J.Y.4
Horand, F.5
Lorenzi, P.L.6
Godfrin, Y.7
-
176
-
-
78650976352
-
L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase
-
Pieters R, Hunger SP, Boos J, Rizzari C, Silverman L, Baruchel A, Goekbuget N, Schrappe M and Pui CH. L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase. Cancer. 2011; 117:238- 249.
-
(2011)
Cancer.
, vol.117
, pp. 238-249
-
-
Pieters, R.1
Hunger, S.P.2
Boos, J.3
Rizzari, C.4
Silverman, L.5
Baruchel, A.6
Goekbuget, N.7
Schrappe, M.8
Pui, C.H.9
-
177
-
-
9044254931
-
Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer
-
O'Dwyer PJ, Hamilton TC, LaCreta FP, Gallo JM, Kilpatrick D, Halbherr T, Brennan J, Bookman MA, Hoffman J, Young RC, Comis RL and Ozols RF. Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer. Journal of clinical oncology. 1996; 14:249-256.
-
(1996)
Journal of clinical oncology.
, vol.14
, pp. 249-256
-
-
O'Dwyer, P.J.1
Hamilton, T.C.2
LaCreta, F.P.3
Gallo, J.M.4
Kilpatrick, D.5
Halbherr, T.6
Brennan, J.7
Bookman, M.A.8
Hoffman, J.9
Young, R.C.10
Comis, R.L.11
Ozols, R.F.12
-
178
-
-
63849267401
-
Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis
-
Lewis-Wambi JS, Kim HR, Wambi C, Patel R, Pyle JR, Klein-Szanto AJ and Jordan VC. Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis. Breast cancer research: BCR. 2008; 10:R104.
-
(2008)
Breast cancer research: BCR.
, vol.10
, pp. R104
-
-
Lewis-Wambi, J.S.1
Kim, H.R.2
Wambi, C.3
Patel, R.4
Pyle, J.R.5
Klein-Szanto, A.J.6
Jordan, V.C.7
-
179
-
-
84884526075
-
Endoplasmic reticulum stress is involved in the response of human laryngeal carcinoma cells to Carboplatin but is absent in Carboplatin-resistant cells
-
Brozovic A, Vukovic L, Polancac DS, Arany I, Koberle B, Fritz G, Fiket Z, Majhen D, Ambriovic-Ristov A and Osmak M. Endoplasmic reticulum stress is involved in the response of human laryngeal carcinoma cells to Carboplatin but is absent in Carboplatin-resistant cells. PloS one. 2013; 8:e76397.
-
(2013)
PloS one.
, vol.8
-
-
Brozovic, A.1
Vukovic, L.2
Polancac, D.S.3
Arany, I.4
Koberle, B.5
Fritz, G.6
Fiket, Z.7
Majhen, D.8
Ambriovic-Ristov, A.9
Osmak, M.10
-
180
-
-
84874038196
-
Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells
-
Yamaguchi H, Hsu JL, Chen CT, Wang YN, Hsu MC, Chang SS, Du Y, Ko HW, Herbst R and Hung MC. Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells. Clinical cancer research. 2013; 19:845-854.
-
(2013)
Clinical cancer research.
, vol.19
, pp. 845-854
-
-
Yamaguchi, H.1
Hsu, J.L.2
Chen, C.T.3
Wang, Y.N.4
Hsu, M.C.5
Chang, S.S.6
Du, Y.7
Ko, H.W.8
Herbst, R.9
Hung, M.C.10
-
181
-
-
33846331650
-
Oxidative stress and cancer: have we moved forward?
-
Halliwell B. Oxidative stress and cancer: have we moved forward? The Biochemical journal. 2007; 401:1-11.
-
(2007)
The Biochemical journal.
, vol.401
, pp. 1-11
-
-
Halliwell, B.1
-
182
-
-
84879611485
-
(-)-Xanthatin induces the prolonged expression of c-Fos through an N-acetyl-L-cysteine (NAC)-sensitive mechanism in human breast cancer MDA-MB-231 cells
-
Takeda S, Nishimura H, Koyachi K, Matsumoto K, Yoshida K, Okamoto Y, Amamoto T, Shindo M and Aramaki H. (-)-Xanthatin induces the prolonged expression of c-Fos through an N-acetyl-L-cysteine (NAC)-sensitive mechanism in human breast cancer MDA-MB-231 cells. The Journal of toxicological sciences. 2013; 38:547-557.
-
(2013)
The Journal of toxicological sciences.
, vol.38
, pp. 547-557
-
-
Takeda, S.1
Nishimura, H.2
Koyachi, K.3
Matsumoto, K.4
Yoshida, K.5
Okamoto, Y.6
Amamoto, T.7
Shindo, M.8
Aramaki, H.9
-
183
-
-
33748935959
-
Inhibition of Ca2+ influx is required for mitochondrial reactive oxygen species-induced endoplasmic reticulum Ca2+ depletion and cell death in leukemia cells
-
Zhang Y, Soboloff J, Zhu Z and Berger SA. Inhibition of Ca2+ influx is required for mitochondrial reactive oxygen species-induced endoplasmic reticulum Ca2+ depletion and cell death in leukemia cells. Molecular pharmacology. 2006; 70:1424-1434.
-
(2006)
Molecular pharmacology.
, vol.70
, pp. 1424-1434
-
-
Zhang, Y.1
Soboloff, J.2
Zhu, Z.3
Berger, S.A.4
-
184
-
-
33746353433
-
Bystander effects are induced by CENU treatment and associated with altered protein secretory activity of treated tumor cells: a relay for chemotherapy?
-
Demidem A, Morvan D and Madelmont JC. Bystander effects are induced by CENU treatment and associated with altered protein secretory activity of treated tumor cells: a relay for chemotherapy? International journal of cancer. 2006; 119:992-1004.
-
(2006)
International journal of cancer.
, vol.119
, pp. 992-1004
-
-
Demidem, A.1
Morvan, D.2
Madelmont, J.C.3
-
185
-
-
84862646896
-
Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells
-
Lin CJ, Lee CC, Shih YL, Lin CH, Wang SH, Chen TH and Shih CM. Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells. PloS one. 2012; 7:e38706.
-
(2012)
PloS one.
, vol.7
-
-
Lin, C.J.1
Lee, C.C.2
Shih, Y.L.3
Lin, C.H.4
Wang, S.H.5
Chen, T.H.6
Shih, C.M.7
-
186
-
-
0037021658
-
Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosisinducing agents
-
Zhu J, Song X, Lin HP, Young DC, Yan S, Marquez VE and Chen CS. Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosisinducing agents. Journal of the National Cancer Institute. 2002; 94:1745-1757.
-
(2002)
Journal of the National Cancer Institute.
, vol.94
, pp. 1745-1757
-
-
Zhu, J.1
Song, X.2
Lin, H.P.3
Young, D.C.4
Yan, S.5
Marquez, V.E.6
Chen, C.S.7
-
187
-
-
34548827350
-
Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo
-
Gills JJ, Lopiccolo J, Tsurutani J, Shoemaker RH, Best CJ, Abu-Asab MS, Borojerdi J, Warfel NA, Gardner ER, Danish M, Hollander MC, Kawabata S, Tsokos M, Figg WD, Steeg PS and Dennis PA. Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo. Clinical cancer research. 2007; 13:5183-5194.
-
(2007)
Clinical cancer research.
, vol.13
, pp. 5183-5194
-
-
Gills, J.J.1
Lopiccolo, J.2
Tsurutani, J.3
Shoemaker, R.H.4
Best, C.J.5
Abu-Asab, M.S.6
Borojerdi, J.7
Warfel, N.A.8
Gardner, E.R.9
Danish, M.10
Hollander, M.C.11
Kawabata, S.12
Tsokos, M.13
Figg, W.D.14
Steeg, P.S.15
Dennis, P.A.16
-
188
-
-
84881010613
-
Nuclear translocation of B-cell-specific transcription factor, BACH2, modulates ROS mediated cytotoxic responses in mantle cell lymphoma
-
Chen Z, Pittman EF, Romaguera J, Fayad L, Wang M, Neelapu SS, McLaughlin P, Kwak L and McCarty N. Nuclear translocation of B-cell-specific transcription factor, BACH2, modulates ROS mediated cytotoxic responses in mantle cell lymphoma. PloS one. 2013; 8:e69126.
-
(2013)
PloS one.
, vol.8
-
-
Chen, Z.1
Pittman, E.F.2
Romaguera, J.3
Fayad, L.4
Wang, M.5
Neelapu, S.S.6
McLaughlin, P.7
Kwak, L.8
McCarty, N.9
-
189
-
-
34848870352
-
Bortezomib for the treatment of mantle cell lymphoma
-
Kane RC, Dagher R, Farrell A, Ko CW, Sridhara R, Justice R and Pazdur R. Bortezomib for the treatment of mantle cell lymphoma. Clinical cancer research. 2007; 13:5291-5294.
-
(2007)
Clinical cancer research.
, vol.13
, pp. 5291-5294
-
-
Kane, R.C.1
Dagher, R.2
Farrell, A.3
Ko, C.W.4
Sridhara, R.5
Justice, R.6
Pazdur, R.7
-
190
-
-
66949171305
-
Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron
-
Simunek T, Sterba M, Popelova O, Adamcova M, Hrdina R and Gersl V. Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron. Pharmacological reports: PR. 2009; 61:154-171.
-
(2009)
Pharmacological reports: PR.
, vol.61
, pp. 154-171
-
-
Simunek, T.1
Sterba, M.2
Popelova, O.3
Adamcova, M.4
Hrdina, R.5
Gersl, V.6
-
191
-
-
84855457952
-
Hsp90 molecular chaperone inhibitors: are we there yet?
-
Neckers L and Workman P. Hsp90 molecular chaperone inhibitors: are we there yet? Clinical cancer research. 2012; 18:64-76.
-
(2012)
Clinical cancer research.
, vol.18
, pp. 64-76
-
-
Neckers, L.1
Workman, P.2
-
192
-
-
33750118400
-
Hemoglobin induces colon cancer cell proliferation by release of reactive oxygen species
-
Lee RA, Kim HA, Kang BY and Kim KH. Hemoglobin induces colon cancer cell proliferation by release of reactive oxygen species. World journal of gastroenterology. 2006; 12:5644-5650.
-
(2006)
World journal of gastroenterology.
, vol.12
, pp. 5644-5650
-
-
Lee, R.A.1
Kim, H.A.2
Kang, B.Y.3
Kim, K.H.4
-
193
-
-
0037099645
-
Mechanisms of action of arsenic trioxide
-
Miller WH, Jr., Schipper HM, Lee JS, Singer J and Waxman S. Mechanisms of action of arsenic trioxide. Cancer research. 2002; 62:3893-3903.
-
(2002)
Cancer research.
, vol.62
, pp. 3893-3903
-
-
Miller, W.H.1
Schipper, H.M.2
Lee, J.S.3
Singer, J.4
Waxman, S.5
-
194
-
-
82655187480
-
Involvement of reactive oxygen species in 2-methoxyestradiol-induced apoptosis in human neuroblastoma cells
-
Zhang Q, Ma Y, Cheng YF, Li WJ, Zhang Z and Chen SY. Involvement of reactive oxygen species in 2-methoxyestradiol-induced apoptosis in human neuroblastoma cells. Cancer letters. 2011; 313:201-210.
-
(2011)
Cancer letters.
, vol.313
, pp. 201-210
-
-
Zhang, Q.1
Ma, Y.2
Cheng, Y.F.3
Li, W.J.4
Zhang, Z.5
Chen, S.Y.6
-
195
-
-
19444370770
-
ROS mediates 4HPR-induced posttranscriptional expression of the Gadd153 gene
-
Lai WL and Wong NS. ROS mediates 4HPR-induced posttranscriptional expression of the Gadd153 gene. Free radical biology & medicine. 2005; 38:1585-1593.
-
(2005)
Free radical biology & medicine.
, vol.38
, pp. 1585-1593
-
-
Lai, W.L.1
Wong, N.S.2
-
196
-
-
84857891632
-
On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
-
Luo X and Kraus WL. On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1. Genes & development. 2012; 26:417-432.
-
(2012)
Genes & development.
, vol.26
, pp. 417-432
-
-
Luo, X.1
Kraus, W.L.2
-
197
-
-
84861541814
-
Ferroptosis: an iron-dependent form of nonapoptotic cell death
-
Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS, Morrison B, 3rd and Stockwell BR. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012; 149:1060-1072.
-
(2012)
Cell.
, vol.149
, pp. 1060-1072
-
-
Dixon, S.J.1
Lemberg, K.M.2
Lamprecht, M.R.3
Skouta, R.4
Zaitsev, E.M.5
Gleason, C.E.6
Patel, D.N.7
Bauer, A.J.8
Cantley, A.M.9
Yang, W.S.10
Morrison, B.11
Stockwell, B.R.12
-
198
-
-
34250372956
-
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels
-
Yagoda N, von Rechenberg M, Zaganjor E, Bauer AJ, Yang WS, Fridman DJ, Wolpaw AJ, Smukste I, Peltier JM, Boniface JJ, Smith R, Lessnick SL, Sahasrabudhe S and Stockwell BR. RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels. Nature. 2007; 447:864-868.
-
(2007)
Nature.
, vol.447
, pp. 864-868
-
-
Yagoda, N.1
von Rechenberg, M.2
Zaganjor, E.3
Bauer, A.J.4
Yang, W.S.5
Fridman, D.J.6
Wolpaw, A.J.7
Smukste, I.8
Peltier, J.M.9
Boniface, J.J.10
Smith, R.11
Lessnick, S.L.12
Sahasrabudhe, S.13
Stockwell, B.R.14
|