Oxidative stress inhibits distant metastasis by human melanoma cells

Nature

Volumn 527, Issue 7577, 2015, Pages 186-191

  Piskounova, Elena ^a   Agathocleous, Michalis ^a   Murphy, Malea M ^a   Hu, Zeping ^a   Huddlestun, Sara E ^a   Zhao, Zhiyu ^a   Leitch, A Marilyn ^a   Johnson, Timothy M ^b   DeBerardinis, Ralph J ^a   Morrison, Sean J ^a,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; FOLIC ACID; GLUTATHIONE; METHOTREXATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; ALDH1L2 PROTEIN, HUMAN; METHYLENETETRAHYDROFOLATE DEHYDROGENASE; MTHFD1 PROTEIN, HUMAN; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXIDOREDUCTASE;

CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; HOMEOSTASIS; RODENT; SKIN; TUMOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; DISTANT METASTASIS; FOLATE METABOLISM; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LIQUID CHROMATOGRAPHY; LOW DRUG DOSE; MELANOMA; MELANOMA CELL; METASTATIC MELANOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; TANDEM MASS SPECTROMETRY; ANIMAL; BLOOD; CANCER TRANSPLANTATION; DEFICIENCY; FEMALE; MALE; METABOLISM; NEOPLASM METASTASIS; NONOBESE DIABETIC MOUSE; PATHOLOGY; SCID MOUSE;

MUS;

ANIMALS; ANTIOXIDANTS; FEMALE; FOLIC ACID; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALE; MELANOMA; METHOTREXATE; METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP); MICE; MICE, INBRED NOD; MICE, SCID; NADP; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; OXIDATIVE STRESS; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS;

EID: 84946903513     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature15726     Document Type: Article

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