Towards understanding promiscuity in multidrug efflux pumps

Trends in Biochemical Sciences

Volumn 39, Issue 1, 2014, Pages 8-16

  Wong, Kelvin ^a   Ma, Jerome ^b   Rothnie, Alice ^c   Biggin, Philip C ^b   Kerr, Ian D ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c ASTON UNIVERSITY   (United Kingdom)

Author keywords

ABC transporter; Antibiotic resistance; Chemotherapy; Drug resistance; MATE transporter; MFS transporter; P glycoprotein.; RND transporter; SMR transporter

Indexed keywords

ABC TRANSPORTER; BREAST CANCER RESISTANCE PROTEIN; CIMETIDINE; DOXORUBICIN; MEMBRANE PROTEIN; METFORMIN; MINOCYCLINE; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN; NORFLOXACIN; QUINOLONE DERIVATIVE;

ANTIBIOTIC RESISTANCE; BINDING SITE; CATALYSIS; DRUG BINDING SITE; DRUG MECHANISM; DRUG TRANSPORT; ENZYME SPECIFICITY; ENZYME STRUCTURE; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; REVIEW;

ABC TRANSPORTER; ANTIBIOTIC RESISTANCE; CHEMOTHERAPY; DRUG RESISTANCE; MATE TRANSPORTER; MFS TRANSPORTER; P-GLYCOPROTEIN.; RND TRANSPORTER; SMR TRANSPORTER;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL OUTER MEMBRANE PROTEINS; BIOLOGICAL TRANSPORT; DRUG RESISTANCE, BACTERIAL; DRUG RESISTANCE, NEOPLASM; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION;

EID: 84890859575     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2013.11.002     Document Type: Review

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