Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1

Journal of Biological Chemistry

Volumn 277, Issue 46, 2002, Pages 44268-44277

  Yang, Youyun ^a   Chen, Qun ^a   Zhang, Jian Ting ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; AMINO ACIDS; BIOLOGICAL MEMBRANES; CONFORMATIONS;

MUTATION;

PROTEINS;

ABC TRANSPORTER; CYSTEINE; LEUKOTRIENE C4; MULTIDRUG RESISTANCE PROTEIN 1;

AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; ALANINE; AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL MEMBRANE; CELL SEPARATION; CELLS, CULTURED; COLCHICINE; CYSTEINE; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; ETOPOSIDE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GLYCOSYLATION; HUMANS; KINETICS; LEUKOTRIENE C4; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; TRANSFECTION; TRYPSIN; VINCRISTINE;

EID: 0037113970     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207003200     Document Type: Article

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