메뉴 건너뛰기




Volumn 19, Issue 15, 2013, Pages 2765-2770

Nuclear translocation of Heme oxygenase-1 confers resistance to imatinib in chronic myeloid leukemia cells

Author keywords

Chronic myeloid leukemia; Heme oxygenase; Imatinib; Nuclear traslocation

Indexed keywords

ACETYLCYSTEINE; BILIRUBIN; CARBON MONOXIDE; HEME OXYGENASE 1; HEMIN; IMATINIB; PROTEINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

EID: 84876712355     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612811319150012     Document Type: Article
Times cited : (90)

References (28)
  • 1
    • 0033614446 scopus 로고    scopus 로고
    • Chronic myeloid leukemia
    • Sawyers CL. Chronic myeloid leukemia. N Engl J Med 1999; 340: 1330-1340.
    • (1999) N Engl J Med , vol.340 , pp. 1330-1340
    • Sawyers, C.L.1
  • 2
    • 0032921194 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors in chronic myeloid leukemia
    • Sawyers CL, Druker B. Tyrosine kinase inhibitors in chronic myeloid leukemia. Cancer J Sci Am 1999; 5: 63-69.
    • (1999) Cancer J Sci Am , vol.5 , pp. 63-69
    • Sawyers, C.L.1    Druker, B.2
  • 3
    • 67349233062 scopus 로고    scopus 로고
    • Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia
    • Hochhaus A, O'Brien SG, Guilhot F, et al. Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia. Leukemia 2009; 23: 1054-1061.
    • (2009) Leukemia , vol.23 , pp. 1054-1061
    • Hochhaus, A.1    O'Brien, S.G.2    Guilhot, F.3
  • 4
    • 33646675638 scopus 로고    scopus 로고
    • Imatinib resistance: Obstacles and opportunities
    • Litzow MR. Imatinib resistance: obstacles and opportunities. Arch Pathol Lab Med 2006; 130: 669-679.
    • (2006) Arch Pathol Lab Med , vol.130 , pp. 669-679
    • Litzow, M.R.1
  • 5
    • 0035800507 scopus 로고    scopus 로고
    • Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
    • Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001; 293: 876-880.
    • (2001) Science , vol.293 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3
  • 6
    • 0036850514 scopus 로고    scopus 로고
    • Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy
    • Hochhaus A, Kreil S, Corbin AS, et al. Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy. Leukemia 2002; 16: 2190-2196.
    • (2002) Leukemia , vol.16 , pp. 2190-2196
    • Hochhaus, A.1    Kreil, S.2    Corbin, A.S.3
  • 7
    • 41349085365 scopus 로고    scopus 로고
    • Targeting of heat shock protein 32 (Hsp32)/heme oxygenase-1 (HO-1) in leukemic cells in chronic myeloid leukemia: A novel approach to overcome resistance against imatinib
    • Mayerhofer M, Gleixner KV, Mayerhofer J, et al. Targeting of heat shock protein 32 (Hsp32)/heme oxygenase-1 (HO-1) in leukemic cells in chronic myeloid leukemia: a novel approach to overcome resistance against imatinib. Blood 2008; 111: 2200-2210.
    • (2008) Blood , vol.111 , pp. 2200-2210
    • Mayerhofer, M.1    Gleixner, K.V.2    Mayerhofer, J.3
  • 8
    • 2342642883 scopus 로고    scopus 로고
    • Identification of heme oxygenase-1 as a novel BCR/ABL-dependent survival factor in chronic myeloid leukemia
    • Mayerhofer M, Florian S, Krauth MT, et al. Identification of heme oxygenase-1 as a novel BCR/ABL-dependent survival factor in chronic myeloid leukemia. Cancer Res 2004; 64: 3148-3154.
    • (2004) Cancer Res , vol.64 , pp. 3148-3154
    • Mayerhofer, M.1    Florian, S.2    Krauth, M.T.3
  • 10
    • 0141988655 scopus 로고    scopus 로고
    • Anti-inflammatory actions of the heme oxygenase-1 pathway
    • Alcaraz MJ, Fernandez P, Guillen MI. Anti-inflammatory actions of the heme oxygenase-1 pathway. Curr Pharm Des 2003; 9: 2541-2551.
    • (2003) Curr Pharm Des , vol.9 , pp. 2541-2551
    • Alcaraz, M.J.1    Fernandez, P.2    Guillen, M.I.3
  • 11
    • 0041630619 scopus 로고    scopus 로고
    • Differential expressions of heme oxygenase-1 gene in CD25- and CD25+ subsets of human CD4+ T cells
    • Pae HO, Oh GS, Choi BM, Chae SC, Chung HT. Differential expressions of heme oxygenase-1 gene in CD25- and CD25+ subsets of human CD4+ T cells. Biochem Biophys Res Commun 2003; 306: 701-705.
    • (2003) Biochem Biophys Res Commun , vol.306 , pp. 701-705
    • Pae, H.O.1    Oh, G.S.2    Choi, B.M.3    Chae, S.C.4    Chung, H.T.5
  • 12
    • 0038418359 scopus 로고    scopus 로고
    • In vivo antitumor activity of pegylated zinc protoporphyrin: Targeted inhibition of heme oxygenase in solid tumor
    • Fang J, Sawa T, Akaike T, et al. In vivo antitumor activity of pegylated zinc protoporphyrin: targeted inhibition of heme oxygenase in solid tumor. Cancer Res 2003; 63: 3567-3574.
    • (2003) Cancer Res , vol.63 , pp. 3567-3574
    • Fang, J.1    Sawa, T.2    Akaike, T.3
  • 13
    • 43549095276 scopus 로고    scopus 로고
    • HO-1 underlies resistance of AML cells to TNF-induced apoptosis
    • Rushworth SA, MacEwan DJ. HO-1 underlies resistance of AML cells to TNF-induced apoptosis. Blood 2008; 111: 3793-3801.
    • (2008) Blood , vol.111 , pp. 3793-3801
    • Rushworth, S.A.1    Macewan, D.J.2
  • 14
    • 0037464355 scopus 로고    scopus 로고
    • Antiapoptotic effect of haem oxygenase-1 induced by nitric oxide in experimental solid tumour
    • Tanaka S, Akaike T, Fang J, et al. Antiapoptotic effect of haem oxygenase-1 induced by nitric oxide in experimental solid tumour. Br J Cancer 2003; 88: 902-909.
    • (2003) Br J Cancer , vol.88 , pp. 902-909
    • Tanaka, S.1    Akaike, T.2    Fang, J.3
  • 15
    • 27744492554 scopus 로고    scopus 로고
    • Therapeutic applications of carbon monoxide-releasing molecules
    • Motterlini R, Mann BE, Foresti R. Therapeutic applications of carbon monoxide-releasing molecules. Expert Opin Investig Drugs 2005; 14: 1305-1318.
    • (2005) Expert Opin Investig Drugs , vol.14 , pp. 1305-1318
    • Motterlini, R.1    Mann, B.E.2    Foresti, R.3
  • 16
    • 53749098423 scopus 로고    scopus 로고
    • Targeting of heat-shock protein 32/heme oxygenase-1 in canine mastocytoma cells is associated with reduced growth and induction of apoptosis
    • Hadzijusufovic E, Rebuzzi L, Gleixner KV, et al. Targeting of heat-shock protein 32/heme oxygenase-1 in canine mastocytoma cells is associated with reduced growth and induction of apoptosis. Exp Hematol 2008; 36: 1461-1470.
    • (2008) Exp Hematol , vol.36 , pp. 1461-1470
    • Hadzijusufovic, E.1    Rebuzzi, L.2    Gleixner, K.V.3
  • 17
    • 84873414511 scopus 로고    scopus 로고
    • Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia
    • Singh MM, Irwin ME, Gao Y, et al. Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia. Cancer 2011.
    • (2011) Cancer
    • Singh, M.M.1    Irwin, M.E.2    Gao, Y.3
  • 18
    • 60649112626 scopus 로고    scopus 로고
    • N-acetyl cysteine enhances imatinib-induced apoptosis of Bcr-Abl+ cells by endothelial nitric oxide synthase-mediated production of nitric oxide
    • Rakshit S, Bagchi J, Mandal L, et al. N-acetyl cysteine enhances imatinib-induced apoptosis of Bcr-Abl+ cells by endothelial nitric oxide synthase-mediated production of nitric oxide. Apoptosis 2009; 14: 298-308.
    • (2009) Apoptosis , vol.14 , pp. 298-308
    • Rakshit, S.1    Bagchi, J.2    Mandal, L.3
  • 19
    • 67650917886 scopus 로고    scopus 로고
    • Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues
    • Juhasz A, Ge Y, Markel S, et al. Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues. Free Radic Res 2009; 43: 523-532.
    • (2009) Free Radic Res , vol.43 , pp. 523-532
    • Juhasz, A.1    Ge, Y.2    Markel, S.3
  • 20
    • 20844448882 scopus 로고    scopus 로고
    • Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species
    • Kim JH, Chu SC, Gramlich JL, et al. Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species. Blood 2005; 105: 1717-1723.
    • (2005) Blood , vol.105 , pp. 1717-1723
    • Kim, J.H.1    Chu, S.C.2    Gramlich, J.L.3
  • 21
    • 84860819704 scopus 로고    scopus 로고
    • Rac2-MRCcIII- generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors
    • Nieborowska-Skorska M, Kopinski PK, Ray R, et al. Rac2-MRCcIII- generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors. Blood 2012; 119: 4253-4263.
    • (2012) Blood , vol.119 , pp. 4253-4263
    • Nieborowska-Skorska, M.1    Kopinski, P.K.2    Ray, R.3
  • 22
    • 81255141176 scopus 로고    scopus 로고
    • BRIT1/MCPH1 expression in chronic myeloid leukemia and its regulation of the G2/M checkpoint
    • Giallongo C, Tibullo D, La Cava P, et al. BRIT1/MCPH1 expression in chronic myeloid leukemia and its regulation of the G2/M checkpoint. Acta Haematol 2011; 126: 205-210.
    • (2011) Acta Haematol , vol.126 , pp. 205-210
    • Giallongo, C.1    Tibullo, D.2    la Cava, P.3
  • 23
    • 2542500611 scopus 로고    scopus 로고
    • The biology of CML blast crisis
    • Calabretta B, Perrotti D. The biology of CML blast crisis. Blood 2004; 103: 4010-4022.
    • (2004) Blood , vol.103 , pp. 4010-4022
    • Calabretta, B.1    Perrotti, D.2
  • 24
    • 84868338894 scopus 로고    scopus 로고
    • Chronic myeloid leukemia stem cells display alterations in the expression of genes involved in oxidative phosphorylation
    • Flis K, Irvine D, Copland M, Bhatia R, Skorski T. Chronic myeloid leukemia stem cells display alterations in the expression of genes involved in oxidative phosphorylation. Leuk Lymphoma 2012.
    • (2012) Leuk Lymphoma
    • Flis, K.1    Irvine, D.2    Copland, M.3    Bhatia, R.4    Skorski, T.5
  • 25
    • 34547135735 scopus 로고    scopus 로고
    • Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress
    • Lin Q, Weis S, Yang G, et al. Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress. J Biol Chem 2007; 282: 20621-20633.
    • (2007) J Biol Chem , vol.282 , pp. 20621-20633
    • Lin, Q.1    Weis, S.2    Yang, G.3
  • 26
    • 33644826711 scopus 로고    scopus 로고
    • Resistance to imatinib: Mechanisms and management
    • Deininger M. Resistance to imatinib: mechanisms and management. J Natl Compr Canc Netw 2005; 3: 757-768.
    • (2005) J Natl Compr Canc Netw , vol.3 , pp. 757-768
    • Deininger, M.1
  • 27
    • 33745086350 scopus 로고    scopus 로고
    • Nilotinib in imatinibresistant CML and Philadelphia chromosome-positive ALL
    • Kantarjian H, Giles F, Wunderle L, et al. Nilotinib in imatinibresistant CML and Philadelphia chromosome-positive ALL. N Engl J Med 2006; 354: 2542-2551.
    • (2006) N Engl J Med , vol.354 , pp. 2542-2551
    • Kantarjian, H.1    Giles, F.2    Wunderle, L.3
  • 28
    • 33745102555 scopus 로고    scopus 로고
    • Dasatinib in imatinibresistant Philadelphia chromosome-positive leukemias
    • Talpaz M, Shah NP, Kantarjian H, et al. Dasatinib in imatinibresistant Philadelphia chromosome-positive leukemias. N Engl J Med 2006; 354: 2531-2541.
    • (2006) N Engl J Med , vol.354 , pp. 2531-2541
    • Talpaz, M.1    Shah, N.P.2    Kantarjian, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.