메뉴 건너뛰기




Volumn 313, Issue 2, 2011, Pages 201-210

Involvement of reactive oxygen species in 2-methoxyestradiol-induced apoptosis in human neuroblastoma cells

Author keywords

2 Methoxyestradiol; Apoptosis; Neuroblastoma; Reactive oxygen species

Indexed keywords

2 METHOXYESTRADIOL; ANTIOXIDANT; APOPTOSIS INDUCING FACTOR; ASCORBIC ACID; CASPASE 3; CASPASE 9; GLUTATHIONE; MITOQ10; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 82655187480     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.09.005     Document Type: Article
Times cited : (47)

References (54)
  • 1
    • 0037366067 scopus 로고    scopus 로고
    • Neuroblastoma: biological insights into a clinical enigma
    • Brodeur G.M. Neuroblastoma: biological insights into a clinical enigma. Nat. Rev. Cancer 2003, 3:203-216.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 203-216
    • Brodeur, G.M.1
  • 2
    • 1842763596 scopus 로고    scopus 로고
    • Neuroblastoma: evolving therapies for a disease with many faces
    • Goldsby R.E., Matthay K.K. Neuroblastoma: evolving therapies for a disease with many faces. Paediatr. Drugs 2004, 6:107-122.
    • (2004) Paediatr. Drugs , vol.6 , pp. 107-122
    • Goldsby, R.E.1    Matthay, K.K.2
  • 8
    • 0000317180 scopus 로고    scopus 로고
    • Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis?
    • Zhu B.T., Conney A.H. Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis?. Cancer Res. 1998, 58:2269-2277.
    • (1998) Cancer Res. , vol.58 , pp. 2269-2277
    • Zhu, B.T.1    Conney, A.H.2
  • 10
    • 0028220858 scopus 로고
    • The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth
    • Fotsis T., Zhang Y., Pepper M.S., Adlercreutz H., Montesano R., Nawroth P.P., Schweigerer L. The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth. Nature 1994, 368:237-239.
    • (1994) Nature , vol.368 , pp. 237-239
    • Fotsis, T.1    Zhang, Y.2    Pepper, M.S.3    Adlercreutz, H.4    Montesano, R.5    Nawroth, P.P.6    Schweigerer, L.7
  • 11
    • 0742269867 scopus 로고    scopus 로고
    • New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent
    • Mooberry S.L. New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent. Curr. Opin. Oncol. 2003, 15:425-430.
    • (2003) Curr. Opin. Oncol. , vol.15 , pp. 425-430
    • Mooberry, S.L.1
  • 12
    • 70349473165 scopus 로고    scopus 로고
    • Potential vascular actions of 2-methoxyestradiol
    • Dubey R.K., Jackson E.K. Potential vascular actions of 2-methoxyestradiol. Trends Endocrinol. Metab. 2009, 20:374-379.
    • (2009) Trends Endocrinol. Metab. , vol.20 , pp. 374-379
    • Dubey, R.K.1    Jackson, E.K.2
  • 13
    • 78650246609 scopus 로고    scopus 로고
    • Additive growth inhibition after combined treatment of 2-methoxyestradiol and conventional chemotherapeutic agents in human pancreatic cancer cells
    • Fotopoulou C., Baumunk D., Schmidt S.C., Schumacher G. Additive growth inhibition after combined treatment of 2-methoxyestradiol and conventional chemotherapeutic agents in human pancreatic cancer cells. Anticancer. Res. 2010, 30:4619-4624.
    • (2010) Anticancer. Res. , vol.30 , pp. 4619-4624
    • Fotopoulou, C.1    Baumunk, D.2    Schmidt, S.C.3    Schumacher, G.4
  • 15
    • 78149240156 scopus 로고    scopus 로고
    • Estrogen metabolomics: a physiologist's perspective
    • Miller V.M. Estrogen metabolomics: a physiologist's perspective. Hypertension 2010, 56:816-818.
    • (2010) Hypertension , vol.56 , pp. 816-818
    • Miller, V.M.1
  • 16
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • Pelicano H., Carney D., Huang P. ROS stress in cancer cells and therapeutic implications. Drug Resist. Updates 2004, 7:97-110.
    • (2004) Drug Resist. Updates , vol.7 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 17
    • 33748165596 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer cells: live by the sword, die by the sword
    • Schumacker P.T. Reactive oxygen species in cancer cells: live by the sword, die by the sword. Cancer Cell 2006, 10:175-176.
    • (2006) Cancer Cell , vol.10 , pp. 175-176
    • Schumacker, P.T.1
  • 18
    • 33745265207 scopus 로고    scopus 로고
    • Reactive oxygen species: role in the development of cancer and various chronic conditions
    • Waris G., Ahsan H. Reactive oxygen species: role in the development of cancer and various chronic conditions. J. Carcinog 2006, 5:14.
    • (2006) J. Carcinog , vol.5 , pp. 14
    • Waris, G.1    Ahsan, H.2
  • 20
    • 0034699513 scopus 로고    scopus 로고
    • Superoxide dismutase as a target for the selective killing of cancer cells
    • Huang P., Feng L., Oldham E.A., Keating M.J., Plunkett W. Superoxide dismutase as a target for the selective killing of cancer cells. Nature 2000, 407:390-395.
    • (2000) Nature , vol.407 , pp. 390-395
    • Huang, P.1    Feng, L.2    Oldham, E.A.3    Keating, M.J.4    Plunkett, W.5
  • 23
    • 0032921582 scopus 로고    scopus 로고
    • A comparative study of the effects of genistein and 2-methoxyestradiol on the proteolytic balance and tumour cell proliferation
    • Fajardo I., Quesada A.R., Nunez de Castro I., Sanchez-Jimenez F., Medina M.A. A comparative study of the effects of genistein and 2-methoxyestradiol on the proteolytic balance and tumour cell proliferation. Brit. J. Cancer 1999, 80:17-24.
    • (1999) Brit. J. Cancer , vol.80 , pp. 17-24
    • Fajardo, I.1    Quesada, A.R.2    Nunez de Castro, I.3    Sanchez-Jimenez, F.4    Medina, M.A.5
  • 24
    • 77950844371 scopus 로고    scopus 로고
    • 2-methoxyestradiol induces morpho-functional changes and impairs the microtubular system in mouse neuroblastoma and rat glioma cells
    • Manca P., Chisu V. 2-methoxyestradiol induces morpho-functional changes and impairs the microtubular system in mouse neuroblastoma and rat glioma cells. Arch. Ital. Biol. 2010, 148:11-21.
    • (2010) Arch. Ital. Biol. , vol.148 , pp. 11-21
    • Manca, P.1    Chisu, V.2
  • 25
    • 0042731370 scopus 로고    scopus 로고
    • Angiostatic treatment of neuroblastoma
    • Wassberg E. Angiostatic treatment of neuroblastoma. Upsala J. Med. Sci. 1999, 104:1-24.
    • (1999) Upsala J. Med. Sci. , vol.104 , pp. 1-24
    • Wassberg, E.1
  • 26
    • 0029880479 scopus 로고    scopus 로고
    • The endogenous estrogen metabolite 2-methoxyestradiol induces apoptotic neuronal cell death in vitro
    • Nakagawa-Yagi Y., Ogane N., Inoki Y., Kitoh N. The endogenous estrogen metabolite 2-methoxyestradiol induces apoptotic neuronal cell death in vitro. Life Sci. 1996, 58:1461-1467.
    • (1996) Life Sci. , vol.58 , pp. 1461-1467
    • Nakagawa-Yagi, Y.1    Ogane, N.2    Inoki, Y.3    Kitoh, N.4
  • 27
    • 18144363210 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors induce DNA damage via reactive oxygen species in human cancer cells
    • Pan J., She M., Xu Z.X., Sun L., Yeung S.C. Farnesyltransferase inhibitors induce DNA damage via reactive oxygen species in human cancer cells. Cancer Res. 2005, 65:3671-3681.
    • (2005) Cancer Res. , vol.65 , pp. 3671-3681
    • Pan, J.1    She, M.2    Xu, Z.X.3    Sun, L.4    Yeung, S.C.5
  • 29
    • 33847679548 scopus 로고    scopus 로고
    • Comparative cytotoxicity and ROS generation by curcumin and tetrahydrocurcumin following visible-light irradiation or treatment with horseradish peroxidase
    • Atsumi T., Tonosaki K., Fujisawa S. Comparative cytotoxicity and ROS generation by curcumin and tetrahydrocurcumin following visible-light irradiation or treatment with horseradish peroxidase. Anticancer Res. 2007, 27:363-371.
    • (2007) Anticancer Res. , vol.27 , pp. 363-371
    • Atsumi, T.1    Tonosaki, K.2    Fujisawa, S.3
  • 30
    • 34548448874 scopus 로고    scopus 로고
    • Salvicine, a novel topoisomerase II inhibitor, exerts its potent anticancer activity by ROS generation
    • Meng L.H., Ding J. Salvicine, a novel topoisomerase II inhibitor, exerts its potent anticancer activity by ROS generation. Acta Pharmacol. Sin. 2007, 28:1460-1465.
    • (2007) Acta Pharmacol. Sin. , vol.28 , pp. 1460-1465
    • Meng, L.H.1    Ding, J.2
  • 31
    • 0034806972 scopus 로고    scopus 로고
    • Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress
    • Benhar M., Dalyot I., Engelberg D., Levitzki A. Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress. Mol. Cell. Biol. 2001, 21:6913-6926.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 6913-6926
    • Benhar, M.1    Dalyot, I.2    Engelberg, D.3    Levitzki, A.4
  • 32
    • 0037125040 scopus 로고    scopus 로고
    • Implication of mitochondria-derived ROS and cardiolipin peroxidation in N-(4-hydroxyphenyl)retinamide-induced apoptosis
    • Asumendi A., Morales M.C., Alvarez A., Arechaga J., Perez-Yarza G. Implication of mitochondria-derived ROS and cardiolipin peroxidation in N-(4-hydroxyphenyl)retinamide-induced apoptosis. Brit. J. Cancer 2002, 86:1951-1956.
    • (2002) Brit. J. Cancer , vol.86 , pp. 1951-1956
    • Asumendi, A.1    Morales, M.C.2    Alvarez, A.3    Arechaga, J.4    Perez-Yarza, G.5
  • 33
    • 0034283773 scopus 로고    scopus 로고
    • Comparison of 2-methoxyestradiol-induced, docetaxel-induced, and paclitaxel-induced apoptosis in hepatoma cells and its correlation with reactive oxygen species
    • Lin H.L., Liu T.Y., Chau G.Y., Lui W.Y., Chi C.W. Comparison of 2-methoxyestradiol-induced, docetaxel-induced, and paclitaxel-induced apoptosis in hepatoma cells and its correlation with reactive oxygen species. Cancer 2000, 89:983-994.
    • (2000) Cancer , vol.89 , pp. 983-994
    • Lin, H.L.1    Liu, T.Y.2    Chau, G.Y.3    Lui, W.Y.4    Chi, C.W.5
  • 34
    • 0343776197 scopus 로고    scopus 로고
    • Role of reactive oxygen species in apoptosis: implications for cancer therapy
    • Mates J.M., Sanchez-Jimenez F.M. Role of reactive oxygen species in apoptosis: implications for cancer therapy. Int. J. Biochem. Cell Biol. 2000, 32:157-170.
    • (2000) Int. J. Biochem. Cell Biol. , vol.32 , pp. 157-170
    • Mates, J.M.1    Sanchez-Jimenez, F.M.2
  • 35
    • 34347398891 scopus 로고    scopus 로고
    • Requirement of reactive oxygen species generation in apoptosis of leukemia cells induced by 2-methoxyestradiol
    • She M.R., Li J.G., Guo K.Y., Lin W., Du X., Niu X.Q. Requirement of reactive oxygen species generation in apoptosis of leukemia cells induced by 2-methoxyestradiol. Acta Pharmacol. Sin. 2007, 28:1037-1044.
    • (2007) Acta Pharmacol. Sin. , vol.28 , pp. 1037-1044
    • She, M.R.1    Li, J.G.2    Guo, K.Y.3    Lin, W.4    Du, X.5    Niu, X.Q.6
  • 36
    • 0037926836 scopus 로고    scopus 로고
    • Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents
    • Zhou Y., Hileman E.O., Plunkett W., Keating M.J., Huang P. Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents. Blood 2003, 101:4098-4104.
    • (2003) Blood , vol.101 , pp. 4098-4104
    • Zhou, Y.1    Hileman, E.O.2    Plunkett, W.3    Keating, M.J.4    Huang, P.5
  • 38
    • 19844369277 scopus 로고    scopus 로고
    • 2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process
    • Gao N., Rahmani M., Dent P., Grant S. 2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process. Oncogene 2005, 24:3797-3809.
    • (2005) Oncogene , vol.24 , pp. 3797-3809
    • Gao, N.1    Rahmani, M.2    Dent, P.3    Grant, S.4
  • 39
    • 0035423951 scopus 로고    scopus 로고
    • 2-Methoxyestradiol-induced caspase-3 activation and apoptosis occurs through G(2)/M arrest dependent and independent pathways in gastric carcinoma cells
    • Lin H.L., Liu T.Y., Wu C.W., Chi C.W. 2-Methoxyestradiol-induced caspase-3 activation and apoptosis occurs through G(2)/M arrest dependent and independent pathways in gastric carcinoma cells. Cancer 2001, 92:500-509.
    • (2001) Cancer , vol.92 , pp. 500-509
    • Lin, H.L.1    Liu, T.Y.2    Wu, C.W.3    Chi, C.W.4
  • 40
    • 74149083977 scopus 로고    scopus 로고
    • 2-Methoxyestradiol induces endoreduplication through the induction of mitochondrial oxidative stress and the activation of MAPK signaling pathways
    • Ting C.M., Lee Y.M., Wong C.K., Wong A.S., Lung H.L., Lung M.L., Lo K.W., Wong R.N., Mak N.K. 2-Methoxyestradiol induces endoreduplication through the induction of mitochondrial oxidative stress and the activation of MAPK signaling pathways. Biochem. Pharmacol. 2010, 79:825-841.
    • (2010) Biochem. Pharmacol. , vol.79 , pp. 825-841
    • Ting, C.M.1    Lee, Y.M.2    Wong, C.K.3    Wong, A.S.4    Lung, H.L.5    Lung, M.L.6    Lo, K.W.7    Wong, R.N.8    Mak, N.K.9
  • 41
    • 73949149189 scopus 로고    scopus 로고
    • Structure activity analysis of 2-methoxyestradiol analogues reveals targeting of microtubules as the major mechanism of antiproliferative and proapoptotic activity
    • Chua Y.S., Chua Y.L., Hagen T. Structure activity analysis of 2-methoxyestradiol analogues reveals targeting of microtubules as the major mechanism of antiproliferative and proapoptotic activity. Mol. Cancer Ther. 2010, 9:224-235.
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 224-235
    • Chua, Y.S.1    Chua, Y.L.2    Hagen, T.3
  • 42
    • 30344433284 scopus 로고    scopus 로고
    • Synergistic antileukemic interactions between 2-medroxyestradiol (2-ME) and histone deacetylase inhibitors involve Akt down-regulation and oxidative stress
    • Gao N., Rahmani M., Shi X., Dent P., Grant S. Synergistic antileukemic interactions between 2-medroxyestradiol (2-ME) and histone deacetylase inhibitors involve Akt down-regulation and oxidative stress. Blood 2006, 107:241-249.
    • (2006) Blood , vol.107 , pp. 241-249
    • Gao, N.1    Rahmani, M.2    Shi, X.3    Dent, P.4    Grant, S.5
  • 43
    • 0038531029 scopus 로고    scopus 로고
    • 2-Methoxyestradiol induces apoptosis in Ewing sarcoma cells through mitochondrial hydrogen peroxide production
    • Djavaheri-Mergny M., Wietzerbin J., Besancon F. 2-Methoxyestradiol induces apoptosis in Ewing sarcoma cells through mitochondrial hydrogen peroxide production. Oncogene 2003, 22:2558-2567.
    • (2003) Oncogene , vol.22 , pp. 2558-2567
    • Djavaheri-Mergny, M.1    Wietzerbin, J.2    Besancon, F.3
  • 44
    • 34347326310 scopus 로고    scopus 로고
    • Lung cancer screening: current situation and perspective
    • Guessous I., Cornuz J., Paccaud F. Lung cancer screening: current situation and perspective. Swiss Med. Wkly. 2007, 137:304-311.
    • (2007) Swiss Med. Wkly. , vol.137 , pp. 304-311
    • Guessous, I.1    Cornuz, J.2    Paccaud, F.3
  • 45
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green D.R., Reed J.C. Mitochondria and apoptosis. Science 1998, 281:1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 46
    • 0034068601 scopus 로고    scopus 로고
    • Mitochondrial control of cell death
    • Kroemer G., Reed J.C. Mitochondrial control of cell death. Nat. Med. 2000, 6:513-519.
    • (2000) Nat. Med. , vol.6 , pp. 513-519
    • Kroemer, G.1    Reed, J.C.2
  • 48
    • 33644663668 scopus 로고    scopus 로고
    • Essential roles of the Bcl-2 family of proteins in caspase-2-induced apoptosis
    • Gao Z., Shao Y., Jiang X. Essential roles of the Bcl-2 family of proteins in caspase-2-induced apoptosis. J. Biol. Chem. 2005, 280:38271-38275.
    • (2005) J. Biol. Chem. , vol.280 , pp. 38271-38275
    • Gao, Z.1    Shao, Y.2    Jiang, X.3
  • 50
    • 0346787534 scopus 로고    scopus 로고
    • 2-methoxyestradiol induces caspase-independent, mitochondria-centered apoptosis in DS-sarcoma cells
    • Lambert C., Apel K., Biesalski H.K., Frank J. 2-methoxyestradiol induces caspase-independent, mitochondria-centered apoptosis in DS-sarcoma cells. Int. J. Cancer 2004, 108:493-501.
    • (2004) Int. J. Cancer , vol.108 , pp. 493-501
    • Lambert, C.1    Apel, K.2    Biesalski, H.K.3    Frank, J.4
  • 52
    • 20444392739 scopus 로고    scopus 로고
    • Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools.
    • James A.M., Cocheme H.M., Smith R.A., Murphy M.P. Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J. Biol. Chem. 2005, 280:21295-21312.
    • (2005) J. Biol. Chem. , vol.280 , pp. 21295-21312
    • James, A.M.1    Cocheme, H.M.2    Smith, R.A.3    Murphy, M.P.4
  • 53
    • 0343986284 scopus 로고    scopus 로고
    • Drug delivery to mitochondria: the key to mitochondrial medicine
    • Murphy M.P., Smith R.A. Drug delivery to mitochondria: the key to mitochondrial medicine. Adv. Drug. Deliv. Rev. 2000, 41:235-250.
    • (2000) Adv. Drug. Deliv. Rev. , vol.41 , pp. 235-250
    • Murphy, M.P.1    Smith, R.A.2
  • 54
    • 0037965634 scopus 로고    scopus 로고
    • Drug delivery to mitochondria: the key to mitochondrial medicine, delivery of bioactive molecules to mitochondria in vivo
    • Smith R.A., Porteous C.M., Gane A.M., Murphy M.P. Drug delivery to mitochondria: the key to mitochondrial medicine, delivery of bioactive molecules to mitochondria in vivo. Proc. Natl. Acad. Sci. USA 2003, 100:5407-5412.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5407-5412
    • Smith, R.A.1    Porteous, C.M.2    Gane, A.M.3    Murphy, M.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.