Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1)

Biochemistry

Volumn 42, Issue 18, 2003, Pages 5214-5224

  Leslie, Elaine M ^a   Létourneau, Isabelle J ^a   Deeley, Roger G ^a   Cole, Susan P C ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

NEGATIVE IONS; NITROGEN COMPOUNDS; SUBSTITUTION REACTIONS;

PLASMA MEMBRANES;

PROTEINS;

ALANINE; AMIDE; ARSENIC TRIOXIDE; CYSTEINE; MULTIDRUG RESISTANCE PROTEIN 1; MUTANT PROTEIN; NUCLEOTIDE BINDING PROTEIN; ORGANIC ANION TRANSPORTER; SERINE; TRYPSIN; VINCRISTINE;

AMINO ACID SUBSTITUTION; ARTICLE; CELL MEMBRANE; CONFOCAL MICROSCOPY; CONTACT SENSITIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; WILD TYPE;

ARSENITES; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CYSTEINE; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; IMMUNOBLOTTING; LEUKOTRIENE C4; LUMINESCENT PROTEINS; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY; TRANSFECTION; VINCRISTINE;

EID: 0037882044     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi027076n     Document Type: Article

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