-
1
-
-
57649149094
-
The Legionella pneumophila replication vacuole: Making a cosy niche inside host cells
-
Isberg RR, O'Connor TJ, Heidtman M (2009) The Legionella pneumophila replication vacuole: Making a cosy niche inside host cells. Nat Rev Microbiol 7:13-24.
-
(2009)
Nat Rev Microbiol
, vol.7
, pp. 13-24
-
-
Isberg, R.R.1
O'Connor, T.J.2
Heidtman, M.3
-
2
-
-
0026738809
-
Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages
-
Marra A, Blander SJ, Horwitz MA, Shuman HA (1992) Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages. Proc Natl Acad Sci USA 89:9607-9611.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 9607-9611
-
-
Marra, A.1
Blander, S.J.2
Horwitz, M.A.3
Shuman, H.A.4
-
3
-
-
0027472133
-
Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila
-
DOI 10.1111/j.1365-2958.1993.tb01092.x
-
Berger KH, Isberg RR (1993) Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila. Mol Microbiol 7:7-19. (Pubitemid 23011091)
-
(1993)
Molecular Microbiology
, vol.7
, Issue.1
, pp. 7-19
-
-
Berger, K.H.1
Isberg, R.R.2
-
4
-
-
0032488861
-
Conjugative transfer by the virulence system of Legionella pneumophila
-
DOI 10.1126/science.279.5352.873
-
Vogel JP, Andrews HL, Wong SK, Isberg RR (1998) Conjugative transfer by the virulence system of Legionella pneumophila. Science 279:873-876. (Pubitemid 28106283)
-
(1998)
Science
, vol.279
, Issue.5352
, pp. 873-876
-
-
Vogel, J.P.1
Andrews, H.L.2
Wong, S.K.3
Isberg, R.R.4
-
5
-
-
78049370513
-
Modulation of host cell function by Legionella pneumophila type IV effectors
-
Hubber A, Roy CR (2010) Modulation of host cell function by Legionella pneumophila type IV effectors. Annu Rev Cell Dev Biol 26:261-283.
-
(2010)
Annu Rev Cell Dev Biol
, vol.26
, pp. 261-283
-
-
Hubber, A.1
Roy, C.R.2
-
6
-
-
81355138899
-
Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors
-
Ge J, Shao F (2011) Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors. Cell Microbiol 13:1870-1880.
-
(2011)
Cell Microbiol
, vol.13
, pp. 1870-1880
-
-
Ge, J.1
Shao, F.2
-
7
-
-
79952403625
-
Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila
-
Zhu W, et al. (2011) Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila. PLoS ONE 6:e17638.
-
(2011)
PLoS ONE
, vol.6
-
-
Zhu, W.1
-
8
-
-
0023620829
-
Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes
-
Horwitz MA (1987) Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes. J Exp Med 166:1310-1328. (Pubitemid 18051425)
-
(1987)
Journal of Experimental Medicine
, vol.166
, Issue.5
, pp. 1310-1328
-
-
Horwitz, M.A.1
-
9
-
-
77950362382
-
The inflammasomes
-
Schroder K, Tschopp J (2010) The inflammasomes. Cell 140:821-832.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
10
-
-
80053379974
-
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
-
Kofoed EM, Vance RE (2011) Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477:592-595.
-
(2011)
Nature
, vol.477
, pp. 592-595
-
-
Kofoed, E.M.1
Vance, R.E.2
-
11
-
-
80053349020
-
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
-
Zhao Y, et al. (2011) The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477:596-600.
-
(2011)
Nature
, vol.477
, pp. 596-600
-
-
Zhao, Y.1
-
12
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Bürckstümmer T, et al. (2009) An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 10:266-272.
-
(2009)
Nat Immunol
, vol.10
, pp. 266-272
-
-
Bürckstümmer, T.1
-
13
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES (2009) AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458:509-513.
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
14
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, et al. (2009) AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458:514-518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
-
15
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts TL, et al. (2009) HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science 323:1057-1060.
-
(2009)
Science
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
-
16
-
-
33845511552
-
A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death
-
DOI 10.1073/pnas.0609012103
-
Laguna RK, Creasey EA, Li Z, Valtz N, Isberg RR (2006) A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death. Proc Natl Acad Sci USA 103:18745-18750. (Pubitemid 44913481)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.49
, pp. 18745-18750
-
-
Laguna, R.K.1
Creasey, E.A.2
Li, Z.3
Valtz, N.4
Isberg, R.R.5
-
17
-
-
33846024748
-
Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf
-
DOI 10.1074/jbc.M604933200
-
Amer A, et al. (2006) Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf. J Biol Chem 281:35217-35223. (Pubitemid 46043249)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.46
, pp. 35217-35223
-
-
Amer, A.1
Franchi, L.2
Kanneganti, T.-D.3
Body-Malapel, M.4
Ozoren, N.5
Brady, G.6
Meshinchi, S.7
Jagirdar, R.8
Gewirtz, A.9
Akira, S.10
Nunez, G.11
-
18
-
-
33645843633
-
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
-
Molofsky AB, et al. (2006) Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection. J Exp Med 203:1093-1104.
-
(2006)
J Exp Med
, vol.203
, pp. 1093-1104
-
-
Molofsky, A.B.1
-
19
-
-
33645791082
-
Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity
-
Ren T, Zamboni DS, Roy CR, Dietrich WF, Vance RE (2006) Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity. PLoS Pathog 2:e18.
-
(2006)
PLoS Pathog
, vol.2
-
-
Ren, T.1
Zamboni, D.S.2
Roy, C.R.3
Dietrich, W.F.4
Vance, R.E.5
-
20
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
DOI 10.1038/sj.cdd.4402194, PII 4402194
-
Fernandes-Alnemri T, et al. (2007) The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ 14:1590-1604. (Pubitemid 47278845)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.9
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.-W.3
Datta, P.4
Miller, B.5
Jankowski, W.6
Rosenberg, S.7
Zhang, J.8
Alnemri, E.S.9
-
21
-
-
33845986012
-
Legionella pneumophila induces IFNβ in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication
-
DOI 10.1074/jbc.M604638200
-
Opitz B, et al. (2006) Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication. J Biol Chem 281:36173-36179. (Pubitemid 46041351)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.47
, pp. 36173-36179
-
-
Opitz, B.1
Vinzing, M.2
Van Laak, V.3
Schmeck, B.4
Heine, G.5
Gunther, S.6
Preissner, R.7
Slevogt, H.8
N'Guessan, P.D.9
Eitel, J.10
Goldmann, T.11
Flieger, A.12
Suttorp, N.13
Hippenstiel, S.14
-
22
-
-
30444450839
-
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
-
DOI 10.1016/j.immuni.2005.12.003, PII S1074761305004115
-
Stetson DB, Medzhitov R (2006) Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 24:93-103. (Pubitemid 43077203)
-
(2006)
Immunity
, vol.24
, Issue.1
, pp. 93-103
-
-
Stetson, D.B.1
Medzhitov, R.2
-
23
-
-
73549090166
-
Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila
-
Monroe KM, McWhirter SM, Vance RE (2009) Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila. PLoS Pathog 5:e1000665.
-
(2009)
PLoS Pathog
, vol.5
-
-
Monroe, K.M.1
McWhirter, S.M.2
Vance, R.E.3
-
24
-
-
68049092912
-
RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
-
Chiu YH, Macmillan JB, Chen ZJ (2009) RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell 138:576-591.
-
(2009)
Cell
, vol.138
, pp. 576-591
-
-
Chiu, Y.H.1
Macmillan, J.B.2
Chen, Z.J.3
-
25
-
-
84857128486
-
Innate immune recognition of francisella tularensis: Activation of type-I interferons and the inflammasome
-
Jones JW, Broz P, Monack DM (2011) Innate immune recognition of francisella tularensis: Activation of type-I interferons and the inflammasome. Front Microbiol 2:16.
-
(2011)
Front Microbiol
, vol.2
, pp. 16
-
-
Jones, J.W.1
Broz, P.2
Monack, D.M.3
-
26
-
-
77951263260
-
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
-
Fernandes-Alnemri T, et al. (2010) The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat Immunol 11:385-393.
-
(2010)
Nat Immunol
, vol.11
, pp. 385-393
-
-
Fernandes-Alnemri, T.1
-
27
-
-
77953116282
-
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
-
Jones JW, et al. (2010) Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. Proc Natl Acad Sci USA 107:9771-9776.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 9771-9776
-
-
Jones, J.W.1
-
28
-
-
0033535542
-
A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins
-
DOI 10.1016/S0960-9822(99)80168-7
-
Kjer-Nielsen L, Teasdale RD, van Vliet C, Gleeson PA (1999) A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins. Curr Biol 9:385-388. (Pubitemid 29194882)
-
(1999)
Current Biology
, vol.9
, Issue.7
, pp. 385-388
-
-
Kjer-Nielsen, L.1
Teasdale, R.D.2
Van Vliet, C.3
Gleeson, P.A.4
-
29
-
-
0033535585
-
The grip domain - A novel golgi-targeting domain found in several coiled-coil proteins
-
DOI 10.1016/S0960-9822(99)80166-3
-
Munro S, Nichols BJ (1999) The GRIP domain - a novel Golgi-targeting domain found in several coiled-coil proteins. Curr Biol 9:377-380. (Pubitemid 29194880)
-
(1999)
Current Biology
, vol.9
, Issue.7
, pp. 377-380
-
-
Munro, S.1
Nichols, B.J.2
-
30
-
-
33748522337
-
Multilayer interactions determine the Golgi localization of GRIP golgins
-
DOI 10.1111/j.1600-0854.2006.00473.x
-
Lu L, Tai G, Wu M, Song H, Hong W (2006) Multilayer interactions determine the Golgi localization of GRIP golgins. Traffic 7:1399-1407. (Pubitemid 44364177)
-
(2006)
Traffic
, vol.7
, Issue.10
, pp. 1399-1407
-
-
Lu, L.1
Tai, G.2
Wu, M.3
Song, H.4
Hong, W.5
-
31
-
-
77955294800
-
Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol
-
Sauer JD, et al. (2010) Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol. Cell Host Microbe 7:412-419.
-
(2010)
Cell Host Microbe
, vol.7
, pp. 412-419
-
-
Sauer, J.D.1
-
32
-
-
78449269290
-
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
-
Miao EA, et al. (2010) Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria. Nat Immunol 11:1136-1142.
-
(2010)
Nat Immunol
, vol.11
, pp. 1136-1142
-
-
Miao, E.A.1
-
33
-
-
70350454786
-
Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4
-
Fortier A, Doiron K, Saleh M, Grinstein S, Gros P (2009) Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4. Infect Immun 77:4794-4805.
-
(2009)
Infect Immun
, vol.77
, pp. 4794-4805
-
-
Fortier, A.1
Doiron, K.2
Saleh, M.3
Grinstein, S.4
Gros, P.5
-
34
-
-
71049179767
-
Interferons direct an effective innate response to Legionella pneumophila infection
-
Plumlee CR, et al. (2009) Interferons direct an effective innate response to Legionella pneumophila infection. J Biol Chem 284:30058-30066.
-
(2009)
J Biol Chem
, vol.284
, pp. 30058-30066
-
-
Plumlee, C.R.1
-
35
-
-
84857752089
-
The protein SdhA maintains the integrity of the Legionella-containing vacuole
-
Creasey EA, Isberg RR (2012) The protein SdhA maintains the integrity of the Legionella-containing vacuole. Proc Natl Acad Sci USA 109:3481-3486.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 3481-3486
-
-
Creasey, E.A.1
Isberg, R.R.2
-
36
-
-
80053337001
-
Biochemistry and cell signaling taught by bacterial effectors
-
Cui J, Shao F (2011) Biochemistry and cell signaling taught by bacterial effectors. Trends Biochem Sci 36:532-540.
-
(2011)
Trends Biochem Sci
, vol.36
, pp. 532-540
-
-
Cui, J.1
Shao, F.2
-
37
-
-
78649819208
-
Chemical probing reveals insights into the signaling mechanism of inflammasome activation
-
Gong YN, et al. (2010) Chemical probing reveals insights into the signaling mechanism of inflammasome activation. Cell Res 20:1289-1305.
-
(2010)
Cell Res
, vol.20
, pp. 1289-1305
-
-
Gong, Y.N.1
|