-
1
-
-
70349459734
-
RIG- I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate
-
Ablasser, A., F. Bauernfeind, G. Hartmann, E. Latz, K.A. Fitzgerald, and V. Hornung. 2009. RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate. Nat. Immunol. 10:1065-1072. http://dx.doi.org/10.1038/ni.1779
-
(2009)
Nat. Immunol
, vol.10
, pp. 1065-1072
-
-
Ablasser, A.1
Bauernfeind, F.2
Hartmann, G.3
Latz, E.4
Fitzgerald, K.A.5
Hornung, V.6
-
2
-
-
11844278344
-
The HIN domain of IFI-200 proteins consists of two OB folds
-
Albrecht, M., D. Choubey, and T. Lengauer. 2005. The HIN domain of IFI-200 proteins consists of two OB folds. Biochem. Biophys. Res. Commun. 327:679-687. http://dx.doi.org/10.1016/j.bbrc.2004.12.056
-
(2005)
Biochem. Biophys. Res. Commun
, vol.327
, pp. 679-687
-
-
Albrecht, M.1
Choubey, D.2
Lengauer, T.3
-
3
-
-
79953062340
-
Nucleic acid recognition by the innate immune system
-
Barbalat, R., S.E. Ewald, M.L. Mouchess, and G.M. Barton. 2011. Nucleic acid recognition by the innate immune system. Annu. Rev. Immunol. 29:185-214. http://dx.doi.org/10.1146/annurev-immunol-031210-101340
-
(2011)
Annu. Rev. Immunol
, vol.29
, pp. 185-214
-
-
Barbalat, R.1
Ewald, S.E.2
Mouchess, M.L.3
Barton, G.M.4
-
4
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Bürckstümmer, T., C. Baumann, S. Blüml, E. Dixit, G. Dürnberger, H. Jahn, M. Planyavsky, M. Bilban, J. Colinge, K.L. Bennett, and G. Superti-Furga. 2009. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat. Immunol. 10:266-272. http://dx.doi.org/10.1038/ni.1702
-
(2009)
Nat. Immunol
, vol.10
, pp. 266-272
-
-
Bürckstümmer, T.1
Baumann, C.2
Blüml, S.3
Dixit, E.4
Dürnberger, G.5
Jahn, H.6
Planyavsky, M.7
Bilban, M.8
Colinge, J.9
Bennett, K.L.10
Superti-Furga, G.11
-
5
-
-
80054966913
-
STING is a direct innate immune sensor of cyclic di-GMP
-
Burdette, D.L., K.M. Monroe, K. Sotelo-Troha, J.S. Iwig, B. Eckert, M. Hyodo, Y. Hayakawa, and R.E. Vance. 2011. STING is a direct innate immune sensor of cyclic di-GMP. Nature. 478:515-518. http://dx.doi.org/10.1038/nature10429
-
(2011)
Nature
, vol.478
, pp. 515-518
-
-
Burdette, D.L.1
Monroe, K.M.2
Sotelo-Troha, K.3
Iwig, J.S.4
Eckert, B.5
Hyodo, M.6
Hayakawa, Y.7
Vance, R.E.8
-
6
-
-
68049092912
-
RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
-
Chiu, Y.H., J.B. Macmillan, and Z.J. Chen. 2009. RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell. 138:576-591. http://dx.doi.org/10.1016/j.cell.2009.06.015
-
(2009)
Cell
, vol.138
, pp. 576-591
-
-
Chiu, Y.H.1
Macmillan, J.B.2
Chen, Z.J.3
-
7
-
-
79956303498
-
Regulation of the antimicrobial response by NLR proteins
-
Elinav, E., T. Strowig, J. Henao-Mejia, and R.A. Flavell. 2011. Regulation of the antimicrobial response by NLR proteins. Immunity. 34:665-679. http://dx.doi.org/10.1016/j.immuni.2011.05.007
-
(2011)
Immunity
, vol.34
, pp. 665-679
-
-
Elinav, E.1
Strowig, T.2
Henao-Mejia, J.3
Flavell, R.A.4
-
8
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri, T., J.W. Yu, P. Datta, J. Wu, and E.S. Alnemri. 2009. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature. 458:509-513. http://dx.doi.org/10.1038/nature07710
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
9
-
-
77951263260
-
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
-
Fernandes-Alnemri, T., J.W. Yu, C. Juliana, L. Solorzano, S. Kang, J. Wu, P. Datta, M. McCormick, L. Huang, E. McDermott, et al. 2010. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat. Immunol. 11:385-393. http://dx.doi.org/10.1038/ni.1859
-
(2010)
Nat. Immunol
, vol.11
, pp. 385-393
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Juliana, C.3
Solorzano, L.4
Kang, S.5
Wu, J.6
Datta, P.7
McCormick, M.8
Huang, L.9
McDermott, E.10
-
10
-
-
84856301080
-
Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease
-
Gall, A., P. Treuting, K.B. Elkon, Y.M. Loo, M. Gale Jr., G.N. Barber, and D.B. Stetson. 2012. Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease. Immunity. 36:120-131. http://dx.doi.org/10.1016/j.immuni.2011.11.018
-
(2012)
Immunity
, vol.36
, pp. 120-131
-
-
Gall, A.1
Treuting, P.2
Elkon, K.B.3
Loo, Y.M.4
Gale Jr., M.5
Barber, G.N.6
Stetson, D.B.7
-
11
-
-
8544241736
-
Retroviral restriction by APOBEC proteins
-
Harris, R.S., and M.T. Liddament. 2004. Retroviral restriction by APOBEC proteins. Nat. Rev. Immunol. 4:868-877. http://dx.doi.org/10.1038/nri1489
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 868-877
-
-
Harris, R.S.1
Liddament, M.T.2
-
12
-
-
75649106430
-
Intracellular DNA recognition
-
Hornung, V., and E. Latz. 2010. Intracellular DNA recognition. Nat. Rev. Immunol. 10:123-130. http://dx.doi.org/10.1038/nri2690
-
(2010)
Nat. Rev. Immunol
, vol.10
, pp. 123-130
-
-
Hornung, V.1
Latz, E.2
-
13
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung, V., A. Ablasser, M. Charrel-Dennis, F. Bauernfeind, G. Horvath, D.R. Caffrey, E. Latz, and K.A. Fitzgerald. 2009. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature. 458:514-518. http://dx.doi.org/10.1038/nature07725
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
Latz, E.7
Fitzgerald, K.A.8
-
14
-
-
38649092410
-
Dendroscope: An interactive viewer for large phylogenetic trees
-
Huson, D.H., D.C. Richter, C. Rausch, T. Dezulian, M. Franz, and R. Rupp. 2007. Dendroscope: An interactive viewer for large phylogenetic trees. BMC Bioinformatics. 8:460. http://dx.doi.org/10.1186/1471-2105-8-460
-
(2007)
BMC Bioinformatics
, vol.8
, pp. 460
-
-
Huson, D.H.1
Richter, D.C.2
Rausch, C.3
Dezulian, T.4
Franz, M.5
Rupp, R.6
-
15
-
-
29244471275
-
A Tolllike receptor-independent antiviral response induced by double-stranded B-form DNA
-
Ishii, K.J., C. Coban, H. Kato, K. Takahashi, Y. Torii, F. Takeshita, H. Ludwig, G. Sutter, K. Suzuki, H. Hemmi, et al. 2006. A Tolllike receptor-independent antiviral response induced by double-stranded B-form DNA. Nat. Immunol. 7:40-48. http://dx.doi.org/10.1038/ni1282
-
(2006)
Nat. Immunol
, vol.7
, pp. 40-48
-
-
Ishii, K.J.1
Coban, C.2
Kato, H.3
Takahashi, K.4
Torii, Y.5
Takeshita, F.6
Ludwig, H.7
Sutter, G.8
Suzuki, K.9
Hemmi, H.10
-
16
-
-
38949093002
-
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
-
Ishii, K.J., T. Kawagoe, S. Koyama, K. Matsui, H. Kumar, T. Kawai, S. Uematsu, O. Takeuchi, F. Takeshita, C. Coban, and S. Akira. 2008. TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature. 451:725-729. http://dx.doi.org/10.1038/nature06537
-
(2008)
Nature
, vol.451
, pp. 725-729
-
-
Ishii, K.J.1
Kawagoe, T.2
Koyama, S.3
Matsui, K.4
Kumar, H.5
Kawai, T.6
Uematsu, S.7
Takeuchi, O.8
Takeshita, F.9
Coban, C.10
Akira, S.11
-
17
-
-
53349178089
-
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
-
Ishikawa, H., and G.N. Barber. 2008. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature. 455:674-678. http://dx.doi.org/10.1038/nature07317
-
(2008)
Nature
, vol.455
, pp. 674-678
-
-
Ishikawa, H.1
Barber, G.N.2
-
18
-
-
70349943834
-
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
-
Ishikawa, H., Z. Ma, and G.N. Barber. 2009. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature. 461:788-792. http://dx.doi.org/10.1038/nature08476
-
(2009)
Nature
, vol.461
, pp. 788-792
-
-
Ishikawa, H.1
Ma, Z.2
Barber, G.N.3
-
19
-
-
77953116282
-
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
-
Jones, J.W., N. Kayagaki, P. Broz, T. Henry, K. Newton, K. O'Rourke, S. Chan, J. Dong, Y. Qu, M. Roose-Girma, et al. 2010. Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. Proc. Natl. Acad. Sci. USA. 107:9771-9776. http://dx.doi.org/10.1073/pnas.1003738107
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 9771-9776
-
-
Jones, J.W.1
Kayagaki, N.2
Broz, P.3
Henry, T.4
Newton, K.5
O'Rourke, K.6
Chan, S.7
Dong, J.8
Qu, Y.9
Roose-Girma, M.10
-
20
-
-
46949097299
-
Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5
-
Kato, H., O. Takeuchi, E. Mikamo-Satoh, R. Hirai, T. Kawai, K. Matsushita, A. Hiiragi, T.S. Dermody, T. Fujita, and S. Akira. 2008. Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5. J. Exp. Med. 205:1601-1610. http://dx.doi.org/10.1084/jem.20080091
-
(2008)
J. Exp. Med
, vol.205
, pp. 1601-1610
-
-
Kato, H.1
Takeuchi, O.2
Mikamo-Satoh, E.3
Hirai, R.4
Kawai, T.5
Matsushita, K.6
Hiiragi, A.7
Dermody, T.S.8
Fujita, T.9
Akira, S.10
-
21
-
-
80052143412
-
RIG- I-like receptors: cytoplasmic sensors for non-self RNA
-
Kato, H., K. Takahasi, and T. Fujita. 2011. RIG-I-like receptors: cytoplasmic sensors for non-self RNA. Immunol. Rev. 243:91-98. http://dx.doi.org/10.1111/j.1600-065X.2011.01052.x
-
(2011)
Immunol. Rev
, vol.243
, pp. 91-98
-
-
Kato, H.1
Takahasi, K.2
Fujita, T.3
-
22
-
-
27144440523
-
IPS- 1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
Kawai, T., K. Takahashi, S. Sato, C. Coban, H. Kumar, H. Kato, K.J. Ishii, O. Takeuchi, and S. Akira. 2005. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 6:981-988. http://dx.doi.org/10.1038/ni1243
-
(2005)
Nat. Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
Kumar, H.5
Kato, H.6
Ishii, K.J.7
Takeuchi, O.8
Akira, S.9
-
23
-
-
0036079158
-
The human genome browser at UCSC
-
Kent, W.J., C.W. Sugnet, T.S. Furey, K.M. Roskin, T.H. Pringle, A.M. Zahler, and D. Haussler. 2002. The human genome browser at UCSC. Genome Res. 12:996-1006.
-
(2002)
Genome Res
, vol.12
, pp. 996-1006
-
-
Kent, W.J.1
Sugnet, C.W.2
Furey, T.S.3
Roskin, K.M.4
Pringle, T.H.5
Zahler, A.M.6
Haussler, D.7
-
24
-
-
79956061094
-
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection
-
Kerur, N., M.V. Veettil, N. Sharma-Walia, V. Bottero, S. Sadagopan, P. Otageri, and B. Chandran. 2011. IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection. Cell Host Microbe. 9:363-375. http://dx.doi.org/10.1016/j.chom.2011.04.008
-
(2011)
Cell Host Microbe
, vol.9
, pp. 363-375
-
-
Kerur, N.1
Veettil, M.V.2
Sharma-Walia, N.3
Bottero, V.4
Sadagopan, S.5
Otageri, P.6
Chandran, B.7
-
25
-
-
79955777383
-
A family of IFN-g-inducible 65-kD GTPases protects against bacterial infection
-
Kim, B.H., A.R. Shenoy, P. Kumar, R. Das, S. Tiwari, and J.D. MacMicking. 2011. A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection. Science. 332:717-721. http://dx.doi.org/10.1126/science.1201711
-
(2011)
Science
, vol.332
, pp. 717-721
-
-
Kim, B.H.1
Shenoy, A.R.2
Kumar, P.3
Das, R.4
Tiwari, S.5
MacMicking, J.D.6
-
26
-
-
0024420119
-
Physical mapping of a family of interferon-activated genes, serum amyloid P-component, and alpha-spectrin on mouse chromosome 1
-
Kingsmore, S.F., J. Snoddy, D. Choubey, P. Lengyel, and M.F. Seldin. 1989. Physical mapping of a family of interferon-activated genes, serum amyloid P-component, and alpha-spectrin on mouse chromosome 1. Immunogenetics. 30:169-174. http://dx.doi.org/10.1007/BF02421202
-
(1989)
Immunogenetics
, vol.30
, pp. 169-174
-
-
Kingsmore, S.F.1
Snoddy, J.2
Choubey, D.3
Lengyel, P.4
Seldin, M.F.5
-
27
-
-
67651125824
-
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
-
McWhirter, S.M., R. Barbalat, K.M. Monroe, M.F. Fontana, M. Hyodo, N.T. Joncker, K.J. Ishii, S. Akira, M. Colonna, Z.J. Chen, et al. 2009. A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP. J. Exp. Med. 206:1899-1911. http://dx.doi.org/10.1084/jem.20082874
-
(2009)
J. Exp. Med
, vol.206
, pp. 1899-1911
-
-
McWhirter, S.M.1
Barbalat, R.2
Monroe, K.M.3
Fontana, M.F.4
Hyodo, M.5
Joncker, N.T.6
Ishii, K.J.7
Akira, S.8
Colonna, M.9
Chen, Z.J.10
-
28
-
-
80055070300
-
Impacts of the Cretaceous Terrestrial Revolution and KPg extinction on mammal diversification
-
Meredith, R.W., J.E. Janečka, J. Gatesy, O.A. Ryder, C.A. Fisher, E.C. Teeling, A. Goodbla, E. Eizirik, T.L. Simão, T. Stadler, et al. 2011. Impacts of the Cretaceous Terrestrial Revolution and KPg extinction on mammal diversification. Science. 334:521-524. http://dx.doi.org/10.1126/science.1211028
-
(2011)
Science
, vol.334
, pp. 521-524
-
-
Meredith, R.W.1
Janecka, J.E.2
Gatesy, J.3
Ryder, O.A.4
Fisher, C.A.5
Teeling, E.C.6
Goodbla, A.7
Eizirik, E.8
Simão, T.L.9
Stadler, T.10
-
29
-
-
40449097257
-
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
-
Muruve, D.A., V. Pétrilli, A.K. Zaiss, L.R. White, S.A. Clark, P.J. Ross, R.J. Parks, and J. Tschopp. 2008. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature. 452:103-107. http://dx.doi.org/10.1038/nature06664
-
(2008)
Nature
, vol.452
, pp. 103-107
-
-
Muruve, D.A.1
Pétrilli, V.2
Zaiss, A.K.3
White, L.R.4
Clark, S.A.5
Ross, P.J.6
Parks, R.J.7
Tschopp, J.8
-
30
-
-
0024410525
-
Interferons as gene activators: a cluster of six interferon-activatable genes is linked to the erythroid alpha-spectrin locus on murine chromosome 1
-
Opdenakker, G., J. Snoddy, D. Choubey, E. Toniato, D.D. Pravtcheva, M.F. Seldin, F.H. Ruddle, and P. Lengyel. 1989. Interferons as gene activators: a cluster of six interferon-activatable genes is linked to the erythroid alpha-spectrin locus on murine chromosome 1. Virology. 171:568-578. http://dx.doi.org/10.1016/0042-6822(89)90626-0
-
(1989)
Virology
, vol.171
, pp. 568-578
-
-
Opdenakker, G.1
Snoddy, J.2
Choubey, D.3
Toniato, E.4
Pravtcheva, D.D.5
Seldin, M.F.6
Ruddle, F.H.7
Lengyel, P.8
-
31
-
-
84858077472
-
The Pfam protein families database
-
Punta, M., P.C. Coggill, R.Y. Eberhardt, J. Mistry, J. Tate, C. Boursnell, N. Pang, K. Forslund, G. Ceric, J. Clements, et al. 2012. The Pfam protein families database. Nucleic Acids Res. 40(Database issue):D290-D301. http://dx.doi.org/10.1093/nar/gkr1065
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.DATABASE ISSUE
-
-
Punta, M.1
Coggill, P.C.2
Eberhardt, R.Y.3
Mistry, J.4
Tate, J.5
Boursnell, C.6
Pang, N.7
Forslund, K.8
Ceric, G.9
Clements, J.10
-
32
-
-
77951269392
-
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
-
Rathinam, V.A., Z. Jiang, S.N. Waggoner, S. Sharma, L.E. Cole, L. Waggoner, S.K. Vanaja, B.G. Monks, S. Ganesan, E. Latz, et al. 2010. The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat. Immunol. 11:395-402. http://dx.doi.org/10.1038/ni.1864
-
(2010)
Nat. Immunol
, vol.11
, pp. 395-402
-
-
Rathinam, V.A.1
Jiang, Z.2
Waggoner, S.N.3
Sharma, S.4
Cole, L.E.5
Waggoner, L.6
Vanaja, S.K.7
Monks, B.G.8
Ganesan, S.9
Latz, E.10
-
33
-
-
34447330454
-
The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis
-
Roberts, Z.J., N. Goutagny, P.Y. Perera, H. Kato, H. Kumar, T. Kawai, S. Akira, R. Savan, D. van Echo, K.A. Fitzgerald, et al. 2007. The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis. J. Exp. Med. 204:1559-1569. http://dx.doi.org/10.1084/jem.20061845
-
(2007)
J. Exp. Med
, vol.204
, pp. 1559-1569
-
-
Roberts, Z.J.1
Goutagny, N.2
Perera, P.Y.3
Kato, H.4
Kumar, H.5
Kawai, T.6
Akira, S.7
Savan, R.8
Van Echo, D.9
Fitzgerald, K.A.10
-
34
-
-
60749104535
-
HIN- 200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts, T.L., A. Idris, J.A. Dunn, G.M. Kelly, C.M. Burnton, S. Hodgson, L.L. Hardy, V. Garceau, M.J. Sweet, I.L. Ross, et al. 2009. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science. 323:1057-1060. http://dx.doi.org/10.1126/science.1169841
-
(2009)
Science
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
Kelly, G.M.4
Burnton, C.M.5
Hodgson, S.6
Hardy, L.L.7
Garceau, V.8
Sweet, M.J.9
Ross, I.L.10
-
35
-
-
0034814052
-
Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus
-
Rozzo, S.J., J.D. Allard, D. Choubey, T.J. Vyse, S. Izui, G. Peltz, and B.L. Kotzin. 2001. Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus. Immunity. 15:435-443. http://dx.doi.org/10.1016/S1074-7613(01)00196-0
-
(2001)
Immunity
, vol.15
, pp. 435-443
-
-
Rozzo, S.J.1
Allard, J.D.2
Choubey, D.3
Vyse, T.J.4
Izui, S.5
Peltz, G.6
Kotzin, B.L.7
-
36
-
-
47949092573
-
Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA
-
Saito, T., D.M. Owen, F. Jiang, J. Marcotrigiano, and M. Gale Jr. 2008. Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA. Nature. 454:523-527. http://dx.doi.org/10.1038/nature07106
-
(2008)
Nature
, vol.454
, pp. 523-527
-
-
Saito, T.1
Owen, D.M.2
Jiang, F.3
Marcotrigiano, J.4
Gale Jr., M.5
-
37
-
-
79251506939
-
The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides
-
Sauer, J.D., K. Sotelo-Troha, J. von Moltke, K.M. Monroe, C.S. Rae, S.W. Brubaker, M. Hyodo, Y. Hayakawa, J.J. Woodward, D.A. Portnoy, and R.E. Vance. 2011. The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infect. Immun. 79:688-694. http://dx.doi.org/10.1128/IAI.00999-10
-
(2011)
Infect. Immun
, vol.79
, pp. 688-694
-
-
Sauer, J.D.1
Sotelo-Troha, K.2
von Moltke, J.3
Monroe, K.M.4
Rae, C.S.5
Brubaker, S.W.6
Hyodo, M.7
Hayakawa, Y.8
Woodward, J.J.9
Portnoy, D.A.10
Vance, R.E.11
-
38
-
-
80052152283
-
The PYHIN protein family as mediators of host defenses
-
Schattgen, S.A., and K.A. Fitzgerald. 2011. The PYHIN protein family as mediators of host defenses. Immunol. Rev. 243:109-118. http://dx.doi.org/10.1111/j.1600-065X.2011.01053.x
-
(2011)
Immunol. Rev
, vol.243
, pp. 109-118
-
-
Schattgen, S.A.1
Fitzgerald, K.A.2
-
39
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth, R.B., L. Sun, C.K. Ea, and Z.J. Chen. 2005. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell. 122:669-682. http://dx.doi.org/10.1016/j.cell.2005.08.012
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
40
-
-
80051880722
-
Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome
-
Sharma, S., R.B. DeOliveira, P. Kalantari, P. Parroche, N. Goutagny, Z. Jiang, J. Chan, D.C. Bartholomeu, F. Lauw, J.P. Hall, et al. 2011. Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome. Immunity. 35:194-207. http://dx.doi.org/10.1016/j.immuni.2011.05.016
-
(2011)
Immunity
, vol.35
, pp. 194-207
-
-
Sharma, S.1
DeOliveira, R.B.2
Kalantari, P.3
Parroche, P.4
Goutagny, N.5
Jiang, Z.6
Chan, J.7
Bartholomeu, D.C.8
Lauw, F.9
Hall, J.P.10
-
41
-
-
18644368714
-
The Bioperl toolkit: Perl modules for the life sciences
-
Stajich, J.E., D. Block, K. Boulez, S.E. Brenner, S.A. Chervitz, C. Dagdigian, G. Fuellen, J.G. Gilbert, I. Korf, H. Lapp, et al. 2002. The Bioperl toolkit: Perl modules for the life sciences. Genome Res. 12:1611-1618. http://dx.doi.org/10.1101/gr.361602
-
(2002)
Genome Res
, vol.12
, pp. 1611-1618
-
-
Stajich, J.E.1
Block, D.2
Boulez, K.3
Brenner, S.E.4
Chervitz, S.A.5
Dagdigian, C.6
Fuellen, G.7
Gilbert, J.G.8
Korf, I.9
Lapp, H.10
-
42
-
-
30444450839
-
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
-
Stetson, D.B., and R. Medzhitov. 2006. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity. 24:93-103. http://dx.doi.org/10.1016/j.immuni.2005.12.003
-
(2006)
Immunity
, vol.24
, pp. 93-103
-
-
Stetson, D.B.1
Medzhitov, R.2
-
43
-
-
49549100511
-
Trex1 prevents cell-intrinsic initiation of autoimmunity
-
Stetson, D.B., J.S. Ko, T. Heidmann, and R. Medzhitov. 2008. Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell. 134:587-598. http://dx.doi.org/10.1016/j.cell.2008.06.032
-
(2008)
Cell
, vol.134
, pp. 587-598
-
-
Stetson, D.B.1
Ko, J.S.2
Heidmann, T.3
Medzhitov, R.4
-
44
-
-
84855989829
-
Inflammasomes in health and disease
-
Strowig, T., J. Henao-Mejia, E. Elinav, and R. Flavell. 2012. Inflammasomes in health and disease. Nature. 481:278-286. http://dx.doi.org/10.1038/nature10759
-
(2012)
Nature
, vol.481
, pp. 278-286
-
-
Strowig, T.1
Henao-Mejia, J.2
Elinav, E.3
Flavell, R.4
-
45
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka, A., Z. Wang, M.K. Choi, H. Yanai, H. Negishi, T. Ban, Y. Lu, M. Miyagishi, T. Kodama, K. Honda, et al. 2007. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature. 448:501-505. http://dx.doi.org/10.1038/nature06013
-
(2007)
Nature
, vol.448
, pp. 501-505
-
-
Takaoka, A.1
Wang, Z.2
Choi, M.K.3
Yanai, H.4
Negishi, H.5
Ban, T.6
Lu, Y.7
Miyagishi, M.8
Kodama, T.9
Honda, K.10
-
46
-
-
80052259316
-
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations
-
Mexico City Childhood Asthma Study (MCAAS); Children's Health Study (CHS) and HARBORS study; Genetics of Asthma in Latino Americans (GALA) Study, Study of Genes-Environment and Admixture in Latino Americans (GALA2) and Study of African Americans, Asthma Genes & Environments (SAGE); Childhood Asthma Research and Education (CARE) Network; Childhood Asthma Management Program (CAMP); Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE); Genetic Research on Asthma in African Diaspora (GRAAD) Study.
-
Torgerson, D.G., E.J. Ampleford, G.Y. Chiu, W.J. Gauderman, C.R. Gignoux, P.E. Graves, B.E. Himes, A.M. Levin, R.A. Mathias, D.B. Hancock, et al. Mexico City Childhood Asthma Study (MCAAS); Children's Health Study (CHS) and HARBORS study; Genetics of Asthma in Latino Americans (GALA) Study, Study of Genes-Environment and Admixture in Latino Americans (GALA2) and Study of African Americans, Asthma, Genes & Environments (SAGE); Childhood Asthma Research and Education (CARE) Network; Childhood Asthma Management Program (CAMP); Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE); Genetic Research on Asthma in African Diaspora (GRAAD) Study. 2011. Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat. Genet. 43:887-892. http://dx.doi.org/10.1038/ng.888
-
(2011)
Nat. Genet
, vol.43
, pp. 887-892
-
-
Torgerson, D.G.1
Ampleford, E.J.2
Chiu, G.Y.3
Gauderman, W.J.4
Gignoux, C.R.5
Graves, P.E.6
Himes, B.E.7
Levin, A.M.8
Mathias, R.A.9
Hancock, D.B.10
-
47
-
-
77958140656
-
IFI16 is an innate immune sensor for intracellular DNA
-
Unterholzner, L., S.E. Keating, M. Baran, K.A. Horan, S.B. Jensen, S. Sharma, C.M. Sirois, T. Jin, E. Latz, T.S. Xiao, et al. 2010. IFI16 is an innate immune sensor for intracellular DNA. Nat. Immunol. 11:997-1004. http://dx.doi.org/10.1038/ni.1932
-
(2010)
Nat. Immunol
, vol.11
, pp. 997-1004
-
-
Unterholzner, L.1
Keating, S.E.2
Baran, M.3
Horan, K.A.4
Jensen, S.B.5
Sharma, S.6
Sirois, C.M.7
Jin, T.8
Latz, E.9
Xiao, T.S.10
-
48
-
-
77958114725
-
The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1
-
Yan, N., A.D. Regalado-Magdos, B. Stiggelbout, M.A. Lee-Kirsch, and J. Lieberman. 2010. The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1. Nat. Immunol. 11:1005-1013. http://dx.doi.org/10.1038/ni.1941
-
(2010)
Nat. Immunol
, vol.11
, pp. 1005-1013
-
-
Yan, N.1
Regalado-Magdos, A.D.2
Stiggelbout, B.3
Lee-Kirsch, M.A.4
Lieberman, J.5
-
49
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama, M., M. Kikuchi, T. Natsukawa, N. Shinobu, T. Imaizumi, M. Miyagishi, K. Taira, S. Akira, and T. Fujita. 2004. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5:730-737. http://dx.doi.org/10.1038/ni1087
-
(2004)
Nat. Immunol
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
Miyagishi, M.6
Taira, K.7
Akira, S.8
Fujita, T.9
-
50
-
-
0036501461
-
Different evolutionary processes shaped the mouse and human olfactory receptor gene families
-
Young, J.M., C. Friedman, E.M. Williams, J.A. Ross, L. Tonnes-Priddy, and B.J. Trask. 2002. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Hum. Mol. Genet. 11:535-546. http://dx.doi.org/10.1093/hmg/11.5.535
-
(2002)
Hum. Mol. Genet
, vol.11
, pp. 535-546
-
-
Young, J.M.1
Friedman, C.2
Williams, E.M.3
Ross, J.A.4
Tonnes-Priddy, L.5
Trask, B.J.6
-
51
-
-
80052969639
-
The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
-
Zhang, Z., B. Yuan, M. Bao, N. Lu, T. Kim, and Y.J. Liu. 2011. The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells. Nat. Immunol. 12:959-965. http://dx.doi.org/10.1038/ni.2091
-
(2011)
Nat. Immunol
, vol.12
, pp. 959-965
-
-
Zhang, Z.1
Yuan, B.2
Bao, M.3
Lu, N.4
Kim, T.5
Liu, Y.J.6
|